Method for the production of sheets of stratum corneum专利检索-细筛净化水处理专利检索查询-专利查询网

Method for the production of sheets of stratum corneum

阅读：463发布：2021-12-23

专利汇可以提供Method for the production of sheets of stratum corneum专利检索，专利查询，专利分析的服务。并且An intact sheet of stratum corneum is obtained by placing a piece of adhesive tape bearing stratum corneum which has been removed from the skin of a donor upon a fine screen with the stratum corneum in contact with the screen. The tape/stratum corneum composite is then continuously washed with a solvent which exerts a softening effect upon the tape adhesive. When the adhesive is sufficiently soft, the tape is removed from the stratum corneum.，下面是Method for the production of sheets of stratum corneum专利的具体信息内容。

权利要求

1. A method of producing a substantially intact sheet of stratum corneum comprising the steps of applying a tape, bearing a pressure-sensitive, solvent-softenable adhesive, to a selected area of the skin of a human donor under conditions of heat and pressure, maintaining said tape on the skin of the donor for a prolonged period and removing said tape from said skin bearing an intact, unfissured layer of stratum corneum supported thereon, placing the carrier tape/stratum corneum composite unit on a fine screen in such manner that an uncovered area of the screen entirely surrounds the composite and the stratum corneum is in contact with said screen, supplying a solvent fluid, which exerts a softening action on the pressure-sensitive adhesive, in a continuous Stream to the upper surface of said screen to maintain a covering of fluid over the composite unit and replace fluid passing through said screen, while lifting one edge of the composite to just raise the edge of the underlying stratum corneum from the screen to initiate separation of the carrier tape from the stratum corneum sheet and thereafter carefully peeling the carrier tape from the stratum corneum, removing the covering of fluid from the stratum corneum and drying the sheet of stratum corneum.

2. A method according to claim 1 further comprising removing the fluid from the underside of the screen by suction and recirculating the removed fluid to the upper side of the screen.

3. A method according to claim 1 further comprising feeding solvent fluid to said covering in a continuous stream extending around the whole periphery of said screen.

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Method for the production of sheets of stratum corneum

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