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5(4)-amino-substituted imidazoles

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专利汇可以提供5(4)-amino-substituted imidazoles专利检索,专利查询,专利分析的服务。并且5(4)-amino-substituted imidazoles are disclosed which are useful as anthelmintics particularly against nematodes. Certain of these imidazole derivatives are novel per se. Pharmaceutical compositions comprising the 5(4)-amino-substituted imidazoles in combination with a pharmaceutically acceptable carrier, diluent or excipient are disclosed as well as methods of treating helminthiosis in animals utilizing these compositions.,下面是5(4)-amino-substituted imidazoles专利的具体信息内容。

  • 2. A compound according to claim 1 wherein R6 is lower alkyl.
  • 3. A compound according to claim 1 wherein R5 is ethoxycarbonyl.
  • 4. A compound according to claim 1 wherein the 5(4)-amino-substituted imidazole is 5-amino-4-ethoxycarbonyl-2-(3''-thienyl) imidazole.
  • 5. A compound according to claim 1 wherein R4 is 2-thienyl and R5 is ethoxycarbonyl and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 6. A compound according to claim 1 wherein R4 is 3-thienyl and R5 is ethoxycarbonyl and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 7. A compound according to claim 1 wherein R4 is 2-furyl and R5 is ethoxycarbonyl and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 8. A compound according to claim 1 wherein R4 is 3-thienyl and R5 is hydrogen and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 9. A compound according to claim 1 wherein R4 is 3-thienyl and R5 is phenyl and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 10. A compound according to claim 1 wherein R4 is 2-thienyl and R5 is phenyl and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 11. A compound according to claim 1 wherein R4 is 3-thienyl and R5 is benzyloxycarbonyl and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 12. A compound according to claim 1 wherein R4 is 3-thienyl and R5 is i-propoxycarbonyl and said 5(4)-amino-substituted imidazole is in the form of the free base or the hydrochloride salt.
  • 13. A compound according to claim 1, wherein R4 is 3-thienyl and R5 is ethoxycarbonyl.
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