Aqueous solution containing fat-soluble drug
专利汇可以提供Aqueous solution containing fat-soluble drug专利检索，专利查询，专利分析的服务。并且PURPOSE: An aqueous solution containing a fat-soluble vitamin active substance or a ubiquinone useful as an injection, having improved stability, obtained by blending the aqueous solution with hydrogenated lecithin and a neutral amino acid, adjusting the blend to a specific pH.
CONSTITUTION: A fat-soluble vitamin active substance such as fat-soluble vitamin A, E, K active substance, etc., or a ubiquinone such as preferably ubidecarenone, and hydrogenated lecithin are added to a small amount of water, pressurized or treated with ultrasonic wave, etc. under heating preferably at 60W70°C, so that they are uniformly dispersed into water coarsely, a neutral amino acid such as glycine, alanine, etc. is added to the dispersion, which is adjusted to 5.5W8pH. The dispersion is blended with other components such as a germicide, an isotonizing agent, etc. and the rest of water, and dispersed uniformly, to give the desired aqueous solution. An amount of the hydrogenated lecithin is 0.1W15pts.wt. based on 1pt.wt. fat-soluble vitamin active substance or ubiquinone, and an amount of the neutral amino acid is preferably 0.05W6wt./vol% based on the aqueous solution.
COPYRIGHT: (C)1985,JPO&Japio，下面是Aqueous solution containing fat-soluble drug专利的具体信息内容。
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