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序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
181 LYSOZYME TRANSGENIC UNGULATES PCT/US2004000606 2004-01-08 WO2004063349A3 2004-11-11 MURRAY JAMES D; ANDERSON GARY B; MAGA ELIZABETH A
The present invention provides transgenic ungulates that include a transgene that encodes lysozyme, and further has an attenuated or non-functional beta-lactoglobulin allele. The invention further provides methods for producing such animals. The invention further provides methods of producing a food product, such as milk, or a milk product, using a subject transgenic ungulate, as well as food products harvested from a subject transgenic ungulate.
182 POWDER COMPOSITION FOR THE DISINFECTION OF UNGULATES' BATHS PCT/EP2012/074464 2012-12-05 WO2013083612A1 2013-06-13 GELMI, Fabio; VENTURINI, Maurizio

A powder composition for the disinfection of ungulates' baths is disclosed. In particular the present invention relates to the use of a powder composition as a disinfecting agent for the preparation of the baths suitable for ungulates' prophylaxis. It comprises at least one chlorinated organic compound, copper sulphate, EDTA, a natural gum and an inorganic carbonate at specific weight percentages.

183 프리온 단백질 활성이 감소된 트랜스제닉 유제동물 및 그의용도 KR1020057008140 2003-11-10 KR1020050093761A 2005-09-23 로블,제임스; 구로이와,요시미; 도미즈까,가즈마; 이시다,이사오
The invention provides cloned transgenic ungulates (e.g., bovines) in which prion protein activity is reduced by one or more genetically engineered mutations. Desirably, these transgenic bovines are also genetically modified to express xenogenous (e.g., human) antibodies. Because of their resistance to prion-related diseases such as bovine spongiform encephalopy (also known as mad cow disease), these bovines are a safer source of human antibodies for pharmaceutical uses and safer source of agricultural products.
184 SHOE AND SHOEING METHOD EP01948918.6 2001-02-01 EP1251733B1 2004-04-14 Poynton, Andrew Paul
A shoe for a hoofed animal, e.g. a horseshoe, is described which comprises a body made from a thermoplastic composition which comprises a matrix of a thermoplastic material which has a softening point of less than 100 DEG C, such as a polycaprolactone. A method of shoeing a hoofed animal, such as a horse, is also described.
185 SHOE AND SHOEING METHOD EP01948918.6 2001-02-01 EP1251733A1 2002-10-30 Poynton, Andrew Paul
A shoe for a hoofed animal, e.g. a horseshoe, is described which comprises a body made from a thermoplastic composition which comprises a matrix of a thermoplastic material which has a softening point of less than 100 °C, such as a polycaprolactone. A method of shoeing a hoofed animal, such as a horse, is also described.
186 Vaccines comprising acapsular P. multocida hyaE deletion mutants US10882666 2004-07-02 US20050106185A1 2005-05-19 Robert Briggs; Fred Tatum
Acapsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent or reduce the severity of hemorrhagic septicemia or pneumonia in mammals, particularly livestock, ungulates, and companion animals, or fowl cholera in birds, particularly poultry.
187 Vaccines comprising acapsular P. multocida hyaE deletion mutants US10882666 2004-07-02 US07351416B2 2008-04-01 Robert E. Briggs; Fred M. Tatum
Acapsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent or reduce the severity of hemorrhagic septicemia or pneumonia in mammals, particularly livestock, ungulates, and companion animals, or fowl cholera in birds, particularly poultry.
188 免疫組合物及方法 COMPOSITION AND METHOD FOR IMMUNIZATION TW097120955 2008-06-05 TW200918552A 2009-05-01 格蘭 湯瑪斯 瑞林 RAWLIN, GRANT THOMAS; 洛伊 邁可 羅冰斯 布朗 ROBINS-BROWNE, ROY MICHAEL; 希爾 羅森布格 ROSENBERG, ZEIL
本發明係有關一種包含多株抗體且用於個體被動免疫對抗EV71之口服製劑組合物;及一種於超免疫有類動物之初乳或者超免疫禽類蛋中產生對抗EV71抗原之多株抗體之方法。
189 ANIMAL REPELLING DEICER PCT/US2011/056698 2011-10-18 WO2013058738A1 2013-04-25 ROSENBURGH, Neil Alexander; DAUM, Michelle Lee; BAGLEY, Jason Louis; PANNELL, Dan; SHELITE, Kristopher

Deicing products designed to deter ungulates are provided, along with methods of using those products to treat iced surfaces. The deicing product comprises a mixture of a deicer along with an ungulate repellent. The repellent can repel based on conditioned avoidance, fear, chemical irritation, and/or bad taste. The deicer can be a salt or a deicer solution. The invention is useful for deterring any ungulate that might be attracted to a component of the deicing product (e.g., the salt), but it is particularly useful for deterring deer.

190 TRANSGENIC ANIMALS AND USES THEREOF US13080923 2011-04-06 US20110231943A1 2011-09-22 JAMES M. ROBL; YOSHIMI KUROIWA; POOTHAPPILLAI KASINATHAN; ISAO ISHIDA; KAZUMA TOMIZUKA
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
191 Method of producing xenogenous antibodies using a bovine US12215085 2008-06-25 US07928285B2 2011-04-19 James M. Robl; Yoshimi Kuroiwa; Poothappillai Kasinathan; Isao Ishida; Kazuma Tomizuka
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
192 Transgenic animals and uses thereof US11111310 2005-04-21 US07420099B2 2008-09-02 James M. Robl; Yoshimi Kuroiwa; Poothappillai Kasinathan; Isao Ishida; Kazuma Tomizuka
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
193 Transgenic animals and uses thereof US11111310 2005-04-21 US20060041945A1 2006-02-23 James Robl; Yoshimi Kuroiwa; Poothappillai Kasinathan; Isao Ishida; Kazuma Tomizuka
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
194 Transgenic animals and uses thereof US12215085 2008-06-25 US20090222935A1 2009-09-03 James M. Robl; Yoshimi Kuroiwa; Poothappillai Kasinathan; Isao Ishida; Kazuma Tomizuka
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and methods of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein.
195 VACCINE AGAINST PAPILLOMATOUS DIGITAL DERMATITIS (PDD) PCT/US1999/026537 1999-11-09 WO00027429A2 2000-05-18
This invention relates to the diagnosis and prevention of ungulate diseases caused by the spirochete bacteria Treponema. The invention specifically relates to isolated cultures of this spirochete and isolated nucleic acids and proteins.
196 EMBRYONIC STEM CELLS FOR MAKING CHIMERIC AND TRANSGENIC UNGULATES PCT/US1994005529 1994-05-16 WO1994026884A1 1994-11-24 BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION; WHEELER, Matthew, B.
Transgenic ungulates and compositions and methods for making and using same, are provided. Central to the invention are porcine, bovine, ovine and caprine embryonic stem cell lines and methods for establishing them. Cells of such lines are transformed with exogenous genetic material of interest and then used to provide chimeric ungulates which have germ cells comprising the exogenous genetic material. The chimeric ungulates are bred to provide transgenic ungulates. The transgenic animals of the invention may show improved qualities and can be used to provide human proteins or peptide hormones or can be used as xenograft donors.
197 Hoof protection agent and hoof protection composition JP2002303673 2002-10-18 JP2003199469A 2003-07-15 SANO TAKASHI; NARITA HIROKAZU
PROBLEM TO BE SOLVED: To provide a hoof-protection agent for ungulates composed mainly of a modified polyester, and provide a protection composition compounded with the agent. SOLUTION: The agent for the protection of the hoof of an ungulate is composed of a polymer produced by partially esterifying a polymer of acrylic acid, methacrylic acid or their mixture with a 4-8C alkyl group or a composition produced by dissolving the polymer in an alcohol. The polymer produced by partially esterifying a polymer of acrylic acid, methacrylic acid or their mixture with a 4-8C alkyl group and the composition containing the polymer are effective for remarkably increasing the strength of the hoof and have a moderate moisture permeability and, accordingly, these materials are useful for the protection of the hoof of ungulates. COPYRIGHT: (C)2003,JPO
198 VACCINE AGAINST PAPILLOMATOUS DIGITAL DERMATITIS (PDD) PCT/US9926537 1999-11-09 WO0027429A3 2000-11-23 WALKER RICHARD L; READ DERYCK H; HIRD DAVID W; LEFEBVRE RANCE B; BERRY STEVEN L; CULLOR JAMES S; LEFLER HANK M
This invention relates to the diagnosis and prevention of ungulate diseases caused by the spirochete bacteria Treponema. The invention specifically relates to isolated cultures of this spirochete and isolated nucleic acids and proteins.
199 Grazing method for controlling and/or eradicating noxious plants including invasive plant species US11304476 2005-12-14 US20060112889A1 2006-06-01 Mark Robbins
The present invention is a method of controlling noxious plant species. The method comprises identifying a target area in a foraging area, selecting a treatment period, selecting an ungulate specie, providing an animal feed supplement at a first deployment location in the target area, and introducing the selected ungulate specie to the animal feed supplement in the target area during the treatment period. The target is considered such because it includes a noxious plant specie. During the treatment period, the selected ungulate specie will interact with the noxious plant specie in the target area. For example, the ungulates interact with the noxious plant specie by eating the noxious plant specie and/or by trampling the noxious plant specie. The animal feed supplement is highly-palatable, portable, self-limiting, attracts the ungulate specie to the target area, and increases the length of stay of the ungulate specie in the target area.
200 Preconditioning a wildlife foraging area US10626293 2003-07-24 US07028639B2 2006-04-18 Mark A. Robbins
The present invention, in one embodiment, is a method of using a plurality of domestic ungulates to precondition a foraging area to enhance the attractiveness of the foraging area to a plurality of wild ungulates. The method comprises selecting the foraging area to be preconditioned, selecting a target period, selecting a preconditioning period, and providing at least one highly palatable, portable, self-limiting, animal feed supplement in the foraging area during the preconditioning period. The target period is when the plurality of wild ungulates uses the foraging area once it has been preconditioned. The preconditioning period is when the plurality of domesticated ungulates preconditions (i.e., forages) the foraging area for use by the wild ungulates during the target period. The highly palatable, portable, self-limiting, animal feed supplement attracts the plurality of domesticated ungulates to the foraging area and increases the length of stay of the plurality of domesticated ungulates in the foraging area.
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