| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 161 | ACAPSULAR P. MULTOCIDA HYAE DELETION MUTANTS | PCT/US2004/021274 | 2004-07-02 | WO2005003330A2 | 2005-01-13 | BRIGGS, Robert, E.; TATUM, Fred, M. |
A capsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent or reduce the severity of hemorrhagic septicemia or pneumonia in mammals, particularly livestock, ungulates, and companion animals, or fowl cholera in birds, particularly poultry. |
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| 162 | 卵胞同期化後の単回リコンビナントウシＦＳＨ | JP2015542272 | 2013-11-15 | JP2016502523A | 2016-01-28 | ソウザ，アレクサンドル; イサカ，ナオミ; キャリー，オード; ティボー，ドミニク |
| 本発明は、生物学的に活性なリコンビナント卵胞刺激ホルモン(rFSH)を使用して、非ヒト哺乳動物において繁殖成績を向上させるための方法及び組成物に関する。本発明はまた、rFSHを使用して、非ヒト哺乳動物において排卵又は胚生産又は妊娠を向上させるための方法に関する。本発明は、特にウシ又はウマなどの有蹄動物で使用され得る。 | ||||||
| 163 | ANTIBODIES SPECIFIC FOR UNGULATE PrP | US11419688 | 2006-05-22 | US20060239996A1 | 2006-10-26 | Stanley Prusiner; Jiri Safar; R. Williamson; Dennis Burton |
| The present invention provides antibodies that specifically bind with a high degree of binding affinity to a native ungulate PrPC and/or a denatured ungulate PrPSc, but not to a native ungulate PrPSc. Preferred antibodies find native bovine PrPC and treated PrPSc but not native bovine PrPSc and can be used in an assay to determine if a sample is infected with infectious prions, i.e. PrPSc. | ||||||
| 164 | DETERMINING IMMUNOGLOBULINS IN NON-BLOOD BODY FLUIDS OF NEONATAL UNGULATES | US14093574 | 2013-12-02 | US20140086902A1 | 2014-03-27 | Nathan L. Smith |
| Provided is a method for determining immunoglobulins in a neonatal ungulate. The method entails obtaining a sample of oral secretions from the neonatal ungulate and measuring an amount of immunoglobulins in the sample of oral secretions. The method is faster and more convenient than previously available methods for determining immunglobulins in neonatal ungulates, such as neonatal horses and cattle. | ||||||
| 165 | Determining Immunoglobulins In Non-Blood Body Fluids Of Neonatal Ungulates | US12610649 | 2009-11-02 | US20100111934A1 | 2010-05-06 | Nathan L. Smith |
| Provided is a method for determining immunoglobulins in a neonatal ungulate. The method entails obtaining a sample of oral secretions from the neonatal ungulate and measuring an amount of immunoglobulins in the sample of oral secretions. The method is faster and more convenient than previously available methods for determining immunglobulins in neonatal ungulates, such as neonatal horses and cattle. | ||||||
| 166 | Method for preventing and/or treating hairy wart disease | US14984655 | 2015-12-30 | US09603827B2 | 2017-03-28 | Keiji Okada; Yasushi Sekiyama |
| Provided is a novel method for preventing and/or treating hairy wart disease which is a hoof and leg disease of ungulates. The method is carried out by administering an isothiocyanic acid ester such as allyl isothiocyanate to a hoof of an ungulate. Examples of ungulates targeted for application of the present invention include cows such as dairy cows as well as sheep, pigs and horses. | ||||||
| 167 | METHOD FOR PREVENTING AND/OR TREATING HAIRY WART DISEASE | US14984655 | 2015-12-30 | US20160106701A1 | 2016-04-21 | Keiji OKADA; Yasushi SEKIYAMA |
| Provided is a novel method for preventing and/or treating hairy wart disease which is a hoof and leg disease of ungulates. The method is carried out by administering an isothiocyanic acid ester such as allyl isothiocyanate to a hoof of an ungulate. Examples of ungulates targeted for application of the present invention include cows such as dairy cows as well as sheep, pigs and horses. | ||||||
| 168 | Determining immunoglobulins in non-blood body fluids of neonatal ungulates | US14093574 | 2013-12-02 | US09012157B2 | 2015-04-21 | Nathan L. Smith |
| Provided is a method for determining immunoglobulins in a neonatal ungulate. The method entails obtaining a sample of oral secretions from the neonatal ungulate and measuring an amount of immunoglobulins in the sample of oral secretions. The method is faster and more convenient than previously available methods for determining immunglobulins in neonatal ungulates, such as neonatal horses and cattle. | ||||||
| 169 | Antibodies specific for ungulate PrP | US10355780 | 2003-01-30 | US07094553B2 | 2006-08-22 | Stanley B. Prusiner; Jiri G. Safar; R. Anthony Williamson; Dennis R. Burton |
| The present invention provides antibodies that specifically bind with a high degree of binding affinity to a native ungulate PrPC and/or a denatured ungulate PrPSc, but not to a native ungulate PrPSc. Preferred antibodies find native bovine PrPC and treated PrPSc but not native bovine PrPSc and can be used in an assay to determine if a sample is infected with infectious prions, i.e. PrPSc. | ||||||
| 170 | TRANSGENIC ANIMALS AND USES THEREOF | PCT/US2005013618 | 2005-04-21 | WO2005104835A3 | 2006-09-28 | ROBL JAMES; KUROIWA YOSHIMI; KASINATHAN POOTHAPPILLAI; ISHIDA ISAO; TOMIZUKA KAZUMA |
| In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and method of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein. | ||||||
| 171 | TRANSGENIC ANIMALS AND USES THEREOF | PCT/US2005/013618 | 2005-04-21 | WO2005104835A2 | 2005-11-10 | ROBL, James; KUROIWA, Yoshimi; KASINATHAN, Poothappillai; ISHIDA, Isao; TOMIZUKA, Kazuma |
In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and method of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein. |
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| 172 | Grazing method for controlling and/or eradicating noxious plants including invasive plant species | US11304476 | 2005-12-14 | US07536979B2 | 2009-05-26 | Mark A. Robbins |
| The present invention is a method of controlling noxious plant species. The method comprises identifying a target area in a foraging area, selecting a treatment period, selecting an ungulate specie, providing an animal feed supplement at a first deployment location in the target area, and introducing the selected ungulate specie to the animal feed supplement in the target area during the treatment period. The target is considered such because it includes a noxious plant specie. During the treatment period, the selected ungulate specie will interact with the noxious plant specie in the target area. For example, the ungulates interact with the noxious plant specie by eating the noxious plant specie and/or by trampling the noxious plant specie. The animal feed supplement is highly-palatable, portable, self-limiting, attracts the ungulate specie to the target area, and increases the length of stay of the ungulate specie in the target area. | ||||||
| 173 | LYSOZYME TRANSGENIC UNGULATES | PCT/US2004/000606 | 2004-01-08 | WO2004063349A2 | 2004-07-29 | MURRAY, James, D.; ANDERSON, Gary, B.; MAGA, Elizabeth, A. |
The present invention provides transgenic ungulates that include a transgene that encodes lysozyme, and further has an attenuated or non-functional β-lactoglobulin allele. The invention further provides methods for producing such animals. The invention further provides methods of producing a food product, such as milk, or a milk product, using a subject transgenic ungulate, as well as food products harvested from a subject transgenic ungulate. |
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| 174 | Antibodies specific for ungulate PrP | US09627218 | 2000-07-27 | US06537548B1 | 2003-03-25 | Stanley B. Prusiner; Jiri Safar; R. Anthony Williamson; Dennis R. Burton |
| The present invention provides antibodies that specifically bind with a high degree of binding affinity to a native ungulate PrPC and/or a denatured ungulate PrPSc, but not to a native ungulate PrPSc. Preferred antibodies find native bovine PrPC and treated PrPSc but not native bovine PrPSc and can be used in an assay to determine if a sample is infected with infectious prions, i.e. PrPSc. | ||||||
| 175 | Diagnostic, Therapeutic And A Vaccine Against Treponemes | US13433258 | 2012-03-28 | US20120251578A1 | 2012-10-04 | Hank (Henry) Michael Lefler |
| The development of a diagnostic, therapeutic and making and administering a vaccine against ungulate diseases which involves spirochete bacteria in particular, Treponemes. | ||||||
| 176 | Preconditioning a wildlife foraging area | US10626293 | 2003-07-24 | US20050081792A1 | 2005-04-21 | Mark Robbins |
| The present invention, in one embodiment, is a method of using a plurality of domestic ungulates to precondition a foraging area to enhance the attractiveness of the foraging area to a plurality of wild ungulates. The method comprises selecting the foraging area to be preconditioned, selecting a target period, selecting a preconditioning period, and providing at least one highly palatable, portable, self-limiting, animal feed supplement in the foraging area during the preconditioning period. The target period is when the plurality of wild ungulates uses the foraging area once it has been preconditioned. The preconditioning period is when the plurality of domesticated ungulates preconditions (i.e., forages) the foraging area for use by the wild ungulates during the target period. The highly palatable, portable, self-limiting, animal feed supplement attracts the plurality of domesticated ungulates to the foraging area and increases the length of stay of the plurality of domesticated ungulates in the foraging area. | ||||||
| 177 | Diagnostic, therapeutic and a vaccine against treponemes | US13433258 | 2012-03-28 | US09364526B2 | 2016-06-14 | Hank (Henry) Michael Lefler |
| The development of a diagnostic, therapeutic and making and administering a vaccine against ungulate diseases which involves spirochete bacteria in particular, Treponemes. | ||||||
| 178 | TRANSGENIC ANIMALS AND USES THEREOF | EP05738421.6 | 2005-04-21 | EP1749102A4 | 2009-02-25 | ROBL, James; KUROIWA, Yoshimi; KASINATHAN, Poothappillai; ISHIDA, Isao; TOMIZUKA, Kazuma |
| In general, the invention features genetically modified non-human mammals (e.g., bovines and other ungulates), and method of making these mammals. In particular, the invention features transgenic ungulates having reduced levels of endogenous IgM heavy chain and/or prion protein. | ||||||
| 179 | Cleaning water for ungulate and cleaning of ungulate by using the same water | JP19392899 | 1999-07-08 | JP2001017016A | 2001-01-23 | ACHINAMI NOBUO; MIYAJI MASATO |
| PROBLEM TO BE SOLVED: To obtain a cleaning water for an ungulate, having a bactericidal effect and bacteria-eradicating effect, increasing the preventing and treating effect toward a hoof disease and useful for the horse, cow, pig, etc., by using electrolytically produced water obtained by using a dilute aqueous solution of a chloride as the water to be electrolyzed. SOLUTION: This cleaning water is electrolytically produced water by using a dilute aqueous solution of a chloride such as table salt as the water to be electrolyzed. Further, the cleaning water for ungulate is an acid water produced at a cathode chamber 22b by an electrolysis using a diaphragm, or an alkaline water produced by an anode chamber 22a, and is preferable that it is a cleaning water for cleaning lower limbs of the ungulate, also for a preliminary cleaning, a first cleaning vessel 11 for storing the alkaline water is used, and for a post cleaning, a second cleaning vessel 12 for storing the acid water is used. It is preferable to clean the ungulate by passing the ungulate to be cleaned through the first cleaning vessel 11 and then passing through the second cleaning vessel 12. COPYRIGHT: (C)2001,JPO | ||||||
| 180 | ACAPSULAR i P. MULTOCIDA HYAE /i DELETION MUTANTS | EP04777430.2 | 2004-07-02 | EP1638598A2 | 2006-03-29 | BRIGGS, Robert, E.; TATUM, Fred, M. |
| A capsular hyaE deletion mutants of P. multocida can be administered to mammals, particularly ungulates, or birds to provide protective immunity against wild-type P. multocida, e.g., to prevent or reduce the severity of hemorrhagic septicemia or pneumonia in mammals, particularly livestock, ungulates, and companion animals, or fowl cholera in birds, particularly poultry. | ||||||
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