| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 121 | Circular dichroism detection system | US10543803 | 2004-01-30 | US20060192959A1 | 2006-08-31 | Spyros Manolopoulos; David Clarke; Peter Read; Gareth Jones; Gareth Derbyshire |
| A detection system comprising modulation means for applying a circular polarisation modulation to an incident beam of radiation, sample holding means through which the modulated beam is passed, a grating to diffract the beam of radiation, an array of solid state detectors arranged to receive different wavelengths of the beam, and processing means arranged to synchronise detected signals with the modulation applied by the modulation means, in order to measure the spectral circular dichroism of the sample. | ||||||
| 122 | アライメント機構を備えた円偏光二色性分光光度計 | JP2012075506 | 2012-03-29 | JP5890719B2 | 2016-03-22 | 角南 哲志; 小勝負 純 |
| 123 | Infrared circular dichroism measuring apparatus and method | EP03013605.5 | 2003-06-16 | EP1376099B1 | 2005-10-05 | Akao, Kenichi; Koshoubu, Jun |
| 124 | 偏光解消板およびこれを用いた円二色性分光装置 | JP2011287105 | 2011-12-28 | JP5926953B2 | 2016-05-25 | 角南 哲志; 小勝負 純; 渡邉 敬祐 |
| 125 | Circular Dichroism Spectrophotometric Method And Circular Dichroism Spectrophotometry Apparatus Using ATR Method | US13114341 | 2011-05-24 | US20110292387A1 | 2011-12-01 | Yoshiro Kondo; Ettore Castiglioni |
| A simple method and apparatus for circular dichroism spectrophotometry are provided that allow a liquid, cream-type, and gel-type specimens having a low degree of transparency to be measured directly and nondestructively without passing light through the specimens. Right-handed or left-handed circularly polarized light enters a prism from an entrance face and hits a specimen mounting face of the prism, on which a specimen is placed, at an angle of 80°. Then, after being totally reflected by the specimen mounting face and going out from an exit face, the light is detected, and the absorbance is determined. | ||||||
| 126 | METHOD AND DEVICE FOR MEASURING CIRCULAR DICHROISM IN REAL TIME | EP08763869.8 | 2008-05-19 | EP2149040A2 | 2010-02-03 | CIPPARRONE, Gabriella; PAGLIUSI, Pasquale; PROVENZANO, Clementina; MAZZULLA, Alfredo |
| Method and device for measuring the circular dichroism of a sample in which a beam of light passes through the said sample, characterised by the fact that the said beam successively passes through a grating and that the diffracted beams are collected and the signals of the diffracted beams are sent to a computer that through a software calculates the value of the circular dichroism, carrying out the logarithm of the diffracted beams intensities ratio. | ||||||
| 127 | 원형이색성,광학회전및흡수스펙트럼측정방법및이색계 | KR1019950703076 | 1994-11-25 | KR1019960700448A | 1996-01-20 | 로코스,지리 |
| 128 | Depolarizer And Circular Dichroism Spectrometer Using The Same | US13727709 | 2012-12-27 | US20130169965A1 | 2013-07-04 | Tetsuji Sunami; Keisuke Watanabe; Jun Koshobu |
| A depolarizer includes a pair of wedge-shaped plates made of an optically isotropic material, laid one on top of another such that the total thickness is constant and wedge-plate holding means for holding the pair of wedge plates separately. The wedge-plate holding means includes a pressure-applying section for applying pressure to each of the pair of wedge plates in a direction perpendicular to the thickness direction of the pair of wedge plates. The pressure-applying direction for one of the pair of wedge plates and the pressure-applying direction for the other of the pair of wedge plates intersect at an angle of 45 degrees. | ||||||
| 129 | Circular dichroism and spectrophotometric absorption detection methods | US639222 | 1991-01-09 | US5246864A | 1993-09-21 | Neil Purdie |
| Spectrophotometric methods, including the use of convention spectroscopic absorption or circular dichroism, for clinical chemistry detection methods. More specifically, with the use of such spectrophotometric methods in the measurement of cholesterol levels and direct measurement of cholesterol subfractions in clinical samples, and in the measurement of lipoprotein levels in a clinical test sample, as well as in the detection of anabolic steroids and other steroid products. The invention is also concerned with providing certain CD and conventional spectrophotometric apparatus useful in each of the aforesaid chemical methods. | ||||||
| 130 | Continuous concentration monitoring by circular dichroism | US383717 | 1989-07-24 | US5036204A | 1991-07-30 | Donald E. Leyden |
| Circularly polarized monochromatic electromagnetic radiation of a wavelength correlating the maximum absorbance of a sample compound is directed through a flowing solution containing the sample compound, which exhibits circular dichroism activity, and a plurality of other compounds. Measurement of the circular dichroism effect and comparison of an alternating current signal corresponding to the circular dichroism absorption to a direct current component allows for the constant monitoring of the concentration of the sample compound in the flowing solution. The flowing solution may be under high temperature and pressure and may comprise a supercritical fluid. | ||||||
| 131 | Circular dichroism detector for HPLC | US188928 | 1998-11-09 | US6118536A | 2000-09-12 | Mitsunori Sakamoto; Hideki Konishi; Katsuji Wakabayashi; Norio Tagawa |
| A circular dichroism detector includes a light source having a large emission intensity in the ultraviolet region such as an HgXe lamp or Hg lamp, a diffraction grating for wavelength dispersing the light emitted from the light source, a polarizer for linearly polarizing the light emitted from the light source, a PEM for modulating wavelength dispersed linearly polarized light to alternately produce left-handed circularly polarized light and right-handed circularly polarized light, a flow cell through which the circularly polarized light will be passed, and a photodiode for detecting the circularly polarized light passing through the flow cell. | ||||||
| 132 | АНАЛИТИЧЕСКАЯ СИСТЕМА ДЛЯ ОПРЕДЕЛЕНИЯ В ЖИДКОСТЯХ, ГЕЛЯХ И ПЛЕНКАХ КОМПОНЕНТОВ, ПРОЯВЛЯЮЩИХ КРУГОВОЙ ДИХРОИЗМ, И ОПТИЧЕСКИЙ ДИФФУЗОМЕТР | PCT/RU2009/000635 | 2009-11-20 | WO2011062516A1 | 2011-05-26 | ГУСЕВ, Владимир Михайлович; КОЛЬЯКОВ, Сергей Федорович; КОМПАНЕЦ, Олег Николаевич; ПАВЛОВ, Михаил Алексеевич; ПАВЛОВ, Андрей Михайлович; ЕВДОКИМОВ, Юрий Михайлович; СКУРИДИН, Сергей Геннадьевич |
Настоящее изобретение представляет собой аналитическую систему для определения в жидкостях, гелях и пленках компонентов, проявляющих круговой дихроизм, содержащую размещенные последовательно оптически соединенные: источник широкополосного светового излучения, содержащий ксеноновую лампу, обеспечивающую расширенный в области УФ излучения диапазон длин волн с повышенным выходом УФ излучения; селектор на основе модифицированного монохроматора Черни-Тернера с компенсацией комы Фасти, содержащий шаговый привод поворота дифракционной решетки с микроконтроллером для управления им; спектральный фильтр для поглощения излучения второго порядка отражения дифракционной решетки селектора; поляризатор; модулятор поляризации; спектральную щель; устройство для размещения пробы, содержащей анализируемую жидкость в контакте с биодатчиком, в оптически проницаемой кювете, выполненной с возможностью размещения в горизонтальном положении с возможностью двухкоординатного перемещения в горизонтальной плоскости; фотоэлектронный умножитель; цифровую систему регистрации; средство обработки полученного электрического сигнала и вычисления концентрации биологически активного вещества. Система может быть выполнена в модульном исполнении, и управление работой системы обеспечивается с помощью встроенного или внешнего компьютера через микроконтроллеры модулей. Система приспособлена для размещения в портативном корпусе. |
||||||
| 133 | Registering apparatus for measuring circular dichroism | US11996361 | 1961-06-27 | US3257894A | 1966-06-28 | MARC GROSJEAN |
| 134 | CIRCULAR DICHROISM AND SPECTROPHOTOMETRIC ABSORPTION DETECTION METHODS AND APPARATUS | EP91902458 | 1991-01-10 | EP0510064A4 | 1992-12-09 | PURDIE, NEIL |
| The present invention is concerned with the use of spectrophotometric methods, including the use of convention spectroscopic absorption or circular dichroism for clinical chemistry detection methods. More specifically, with the use of such spectrophotometric methods in the measurement of cholesterol levels and direct measurement of cholesterol subfractions in clinical samples, and in the measurement of lipoprotein levels in a clinical test sample, as well as in the detection of anabolic steroids and other steroid products. The invention is also concerned with providing certain CD and conventional spectrophotometric apparatus useful in each of the aforesaid chemical methods. | ||||||
| 135 | Circular dichroism optical element, apparatus thereof, and liquid crystal polymer | US981043 | 1997-12-11 | US6103323A | 2000-08-15 | Hironori Motomura; Kyoko Izumi; Shusaku Nakano; Amane Mochizuki |
| A circular dichroism optical element having the solidified layer of a liquid crystal polymer comprising a Grandjean oriented cholesteric liquid crystal phase, a liquid crystal display apparatus using the optical element, and a liquid crystal polymer composed of, as the component, a copolymer comprising at least two kinds of specific acrylic monomer units. | ||||||
| 136 | Circular dichroism and spectrophotometric absorption detection methods and apparatus | US785998 | 1991-10-31 | US5252488A | 1993-10-12 | Neil Purdie |
| Spectrophotometric methods, including the use of circular dichroism, spectrophotometric absorption detection fluorescence and derivative spectrophotometric absorption methods for use in clinical chemistry detection methods. More specifically, with the use of such spectrophotometric methods in the measurement of cholesterol levels and direct measurement of cholesterol subfractions in test samples. The invention is also concerned with providing certain absorption detection spectrophotometric apparatus and spectrophotometric reagents useful in the aforesaid methods. | ||||||
| 137 | Solution Sample Holding Method, Sample Cell, And Circular Dichroism Measuring Apparatus | US13462856 | 2012-05-03 | US20130293887A1 | 2013-11-07 | Ettore Castiglioni; Yoshiro Kondo; Ichitaro Kohge |
| A solution sample holding method between two light-transmitting plate-like members for measuring light passing through a minute amount of solution sample, comprises a dripping step and a covering step. The dripping step is to drip a minute amount of solution sample in a drip area of a sample mounting face of a first light-transmitting member. The sample mounting face also includes a liquid-repellent area surrounding the drip area. The covering step is to cover the solution sample with a second light-transmitting member and to maintain a predetermined distance between the first light-transmitting member and the second light-transmitting member. The liquid-repellent area of the sample mounting face is covered with a liquid-repellent substance. The minute amount of solution sample is held in contact with the two light-transmitting members. | ||||||
| 138 | REACTION MONITORING OF CHIRAL MOLECULES USING FOURIER TRANSFORM INFRARED VIBRATIONAL CIRCULAR DICHROISM SPECTROSCOPY | EP04795570.3 | 2004-10-13 | EP1685386B1 | 2011-04-27 | NAFIE, Laurence, A.; GUO, Changning; DUKOR, Rina, K. |
| A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reaction, and manipulating the spectra to obtain a % EE value. Using such real time information, the reaction parameters can be changed to shift the reaction to produce more of one chiral molecule than another. | ||||||
| 139 | REACTION MONITORING OF CHIRAL MOLECULES USING FOURIER TRANSFORM INFRARED VIBRATIONAL CIRCULAR DICHROISM SPECTROSCOPY | EP04795570.3 | 2004-10-13 | EP1685386A1 | 2006-08-02 | NAFIE, Lawrence, A.; GUO, Changning; DUKOR, Rina, K. |
| A method and apparatus to monitor the enantiomeric excess of chiral molecules participating in a chemical reaction. The method includes real time monitoring of the chemical reaction by obtaining a VCD spectra and an IR spectra of the chemical compounds in the reaction, and manipulating the spectra to obtain a % EE value. Using such real time information, the reaction parameters can be changed to shift the reaction to produce more of one chiral molecule than another. | ||||||
| 140 | Medium measuring surface plasmon resonance sensor having circular dichroism, and method and device for measuring circular dichroism | JP2008055798 | 2008-03-06 | JP2009210495A | 2009-09-17 | SHOJI ATSUSHI |
| <P>PROBLEM TO BE SOLVED: To solve a problem wherein a conventional surface plasmon resonance (SPR) sensor using linearly polarized light cannot sensitively detect circular dichroism, though the SPR sensor can measure refractive index (or dielectric constant) and its variation on a metal surface or near the interface, and easily measure the interaction between various chemical substances and hence can be used as "chemical sensor" capable of sensitively measuring it in real time by biotechnology related researchers. <P>SOLUTION: In the SPR sensor, by forming a shape structure having single or a plurality of periodicities on its metal surface and applying an external magnetic field to the metal part, circularly polarized wave of plasmon is induced around the periodic shape structure, and the circular dichroism is detected by the interaction between evanescent wave from it and an optically active substance. Thus, the circular dichroism of a medium having optical activity can be measured, and L bodies and D bodies as optical isomers of organic substances such as sugar, protein, and amino acid can be distinguished. <P>COPYRIGHT: (C)2009,JPO&INPIT | ||||||
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