Corticosteroid antiiinflammatry drug专利检索- 含有碳氢卤素或氧的正系甾族化合物具有1个与环戊烷并专利检索查询-专利查询网

Corticosteroid antiiinflammatry drug
申请号	JP4041579	申请日	1979-04-05	公开(公告)号	JPS54132563A	公开(公告)日	1979-10-15
申请人	Syntex Inc;			发明人	MAIKERU MAAKUSU; DENISU JIEI KAATESUZU;
摘要	Corticosteroids of the formulae wherein: R is methyl; and R independently is hydrogen, or C2 to C6 linear or branched acyl or R and OR taken together are the radical (IV) where R is hydrogen, C1 to C6 linear or branched alkyl, and R is the same or different than R as defined above or is C1 to C6 linear or branched alkoxy or R and R taken together with the carbon atom of said radical is C4 to C9 heterocyclic alkyl having one heterocyclic atom that is oxygen, R independently is C1 to C6 linear or branched alkyl or C4 to C9 heterocyclic alkyl having one heterocyclic atom that is oxygen; or OR and OR taken together are the radical (IV) where R is defined above and R is C1 to C6 linear or branched alkoxy; Y is selected from the group methyl, halomethyl, and the radical -CH2OC(O)R where R is C2 to C6 linear or branched alkyl; Z independently is C1 to C7 linear or branched acyloxy, hydroxy or halo or Z and OR taken together are the radical (IV) where R and R is defined above; are useful as anti-inflammatory agents. Compounds III can be prepared from compounds I through compounds II.
权利要求
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