Compounds, compositions and methods

申请号 US15480618 申请日 2017-04-06 公开(公告)号 US10035770B2 公开(公告)日 2018-07-31
申请人 Cytokinetics, Incorporated; 发明人 Bradley Paul Morgan; Alex Muci; Pu-Ping Lu; Erica Anne Kraynack; Todd Tochimoto; David J. Morgans, Jr.;
摘要 Certain substituted urea derivatives selectively modulate the cardiac sarcomere, for example by potentiating cardiac myosin, and are useful in the treatment of systolic heart failure including congestive heart failure.
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