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Schistosomiasis treatment

申请号 US80144459 申请日 1959-03-24 公开(公告)号 US3057776A 公开(公告)日 1962-10-09
申请人 PARKE DAVIS & CO; 发明人 SHORT FRANKLIN W; ELSLAGER EDWARD F;
摘要 Orally administrable therapeutic compositions in dosage unit form comprise a pharmaceutical carrier and, as active ingredient, pararosaniline or a salt thereof with a mineral acid or with a p monobasic organic acid containing a single carboxyl or sulphonic acid group. Suitable salts are the hydrochloride (parafusehin), hydrobromide, hydroiodide, acetate, sulphate, palmitate, stearate, salicylate, hydroxynaphthoate and 2-hydroxy-6-naphthalene sulphonate, the compositions preferably containing from 50 to 500 mg. of pararosaniline per dosage unit, e.g. as tablets, powders, capsules, solutions, suspensions and enterically coated forms comprising conventional solid and liquid carriers, diluents, preservatives and flavouring agents.
权利要求
  • 3. A METHOD FOR THE TREATMENT OF SCHISTOSOMIASIS WHICH COMPRISES ADIMISTERING BISPARAROSANILINE PAMOATE TO A LIVING HUMAN BEING IN A DAILY ORAL DOSE OF FROM 500 MILLIGRAAMS TO 4 GRAMS OF PARAOSANILINE CATAION EQUIVALENT.
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