Expanded radix for polymeric tags

申请号 US14921977 申请日 2015-10-23 公开(公告)号 US09909121B2 公开(公告)日 2018-03-06
申请人 Illumina, Inc.; 发明人 Michael P. Weiner;
摘要 A method having steps of (a) providing nucleic acids having a tag sequence (N1)n(N2)n . . . (Nx)n, wherein N1, N2 and Nx are nucleotides that complement different nucleotides, respectively, wherein n is an integer that can differ for N1, N2 and Nx; (b) detecting the nucleic acids individually and under conditions to distinguish signal intensities for (N1)n sequences having different values for n, (N2)n sequences having different values for n and. (Nx)n sequences having different values for n; and (c) distinguishing the tags based on the signal intensities.
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