METHOD FOR OBTAINING CELLS WITH NEW PROPERTIES |
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申请号 | PCT/IB0203398 | 申请日 | 2002-07-08 | 公开(公告)号 | WO03004656A9 | 公开(公告)日 | 2003-06-05 |
申请人 | PASTEUR INSTITUT; CENTRE NAT RECH SCIENT; EVOLOGIC SA; MUTZEL RUPPERT; MARLIERE PHILIPPE; MAZEL DIDIER; | 发明人 | MUTZEL RUPPERT; MARLIERE PHILIPPE; MAZEL DIDIER; | ||||
摘要 | The present invention relates to a method for generating a novel form of life comprising the steps consisting of: a) irreversible alteration of the genome of a microbial clone; b) cultivation of a vast population of microbial cells originating from the altered clone obtained in step a) during numerous generations under conditions allowing selection for a higher and stable proliferation rate; c) isolation of descendant clones within the cultivated population of step b) still bearing the alteration of step a). | ||||||
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说明书全文 |