ENZYME CONSTRUCT

申请号 US15704395 申请日 2017-09-14 公开(公告)号 US20180230526A1 公开(公告)日 2018-08-16
申请人 Oxford Nanopore Technologies Ltd.; 发明人 Andrew John Heron; James Anthony Clarke; Ruth Moysey; Elizabeth Jayne Wallace; Mark Bruce; Lakmal Jayasinghe; Domenico Caprotti; Szabolcs Soeroes; Luke McNeill; Mihaela Misca;
摘要 The invention relates to methods using constructs comprising a helicase and an additional polynucleotide binding moiety. The helicase is attached to the polynucleotide binding moiety and the construct has the ability to control the movement of a polynucleotide. The constructs can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
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