CRYSTAL STRUCTURE OF A TYPE IB P-TYPE ATPASE

申请号 PCT/DK2012050026 申请日 2012-01-20 公开(公告)号 WO2012097826A3 公开(公告)日 2013-03-21
申请人 UNIV AARHUS; NISSEN POUL; GOURDON PONTUS; LIU XIANGYU; PEDERSEN BJOERN PANYELLA; MATTLE DANIEL; 发明人 NISSEN POUL; GOURDON PONTUS; LIU XIANGYU; PEDERSEN BJOERN PANYELLA; MATTLE DANIEL;
摘要 The present invention relates to crystals of a type IB P-type ATPase having the space group P1 and methods for purification and growing said crystals. The invention also presents methods for identifying an inhibitor of a type IB P-type ATPase for example by determining binding interactions between an inhibitor and a set of binding interaction sites in said type IB P-type ATPase.
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