DEVELOPMENT OF HBV-AND/OR HDV-SUSCEPTIBLE CELLS, CELL LINES AND NON-HUMAN ANIMALS |
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申请号 | US14442279 | 申请日 | 2013-11-12 | 公开(公告)号 | US20150299289A1 | 公开(公告)日 | 2015-10-22 |
申请人 | RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG; | 发明人 | Stephan Urban; Yi Ni; | ||||
摘要 | The present invention relates to a novel Hepatitis B virus (HBV) and/or Hepatitis D virus (HDV) receptor and its use for the development of cells, cell lines and non-human animals that are susceptible to HBV and/or HDV infection and can be used for immunological studies and/or for the screening of drugs, post-entry restriction factors and host dependency factors. It further relates to the use of the receptor for the identification of compounds useful in the treatment of HBV and/or HDV infection. | ||||||
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