DEVELOPMENT OF HBV-AND/OR HDV-SUSCEPTIBLE CELLS, CELL LINES AND NON-HUMAN ANIMALS

申请号 US14442279 申请日 2013-11-12 公开(公告)号 US20150299289A1 公开(公告)日 2015-10-22
申请人 RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG; 发明人 Stephan Urban; Yi Ni;
摘要 The present invention relates to a novel Hepatitis B virus (HBV) and/or Hepatitis D virus (HDV) receptor and its use for the development of cells, cell lines and non-human animals that are susceptible to HBV and/or HDV infection and can be used for immunological studies and/or for the screening of drugs, post-entry restriction factors and host dependency factors. It further relates to the use of the receptor for the identification of compounds useful in the treatment of HBV and/or HDV infection.
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