SUPER-ENHANCERS AND METHODS OF USE THEREOF |
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| 申请号 | EP13848637 | 申请日 | 2013-10-25 | 公开(公告)号 | EP2912178A4 | 公开(公告)日 | 2016-05-25 |
| 申请人 | WHITEHEAD BIOMEDICAL INST; | 发明人 | HNISZ DENES; ABRAHAM BRIAN; LEE TONG IHN; YOUNG RICHARD A; | ||||
| 摘要 | The present invention relates in some aspects to super-enhancers and related compositions, methods, and agents that are useful for modulating expression of cell type-specific genes that are required for maintenance of cell identity (e.g., embryonic stem cell identity) or maintenance of a disease state (e.g., cancer). | ||||||
| 权利要求 | |||||||
| 说明书全文 | |||||||
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