Influenza M2 protein mutant viruses as live influenza attenuated vaccines |
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| 申请号 | US15292595 | 申请日 | 2016-10-13 | 公开(公告)号 | US10119124B2 | 公开(公告)日 | 2018-11-06 |
| 申请人 | Wisconsin Alumni Research Foundation (WARF); | 发明人 | Tokiko Watanabe; Yoshihiro Kawaoka; | ||||
| 摘要 | A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus. | ||||||
| 权利要求 | |||||||
| 说明书全文 | |||||||
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