序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 INFLUENZA M2 PROTEIN MUTANT VIRUSES AS LIVE INFLUENZA ATTENUATED VACCINES PCT/US2008007582 2008-06-18 WO2008156778A9 2009-02-12 WATANABE TOKIKO; KAWAOKA YOSHIHIRO
A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.
2 INFLUENZA M2 PROTEIN MUTANT VIRUSES AS LIVE INFLUENZA ATTENUATED VACCINES PCT/US2008007582 2008-06-18 WO2008156778A2 2008-12-24 WATANABE TOKIKO; KAWAOKA YOSHIHIRO
A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus.
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