序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
141 CONTROL OF PHYTOPATHOGENIC MICROORGANISMS WITH PSEUDOMONAS SP. AND SUBSTANCES AND COMPOSITIONS DERIVED THEREFROM US14376696 2013-02-27 US20150030577A1 2015-01-29 Ratnakar Asolkar; Ana Lucia Cordova-Kreylos; Carly Todd
Provided are compounds and compositions derived from Pseudomonas sp., particularly, Pseudomonas fluorescens or Pseudomonas protegens and more particularly strain having the identifying characteristics of Pseudomonas ATCC 55799 having antimicrobial properties and particularly, antibacterial properties.
142 Compound WS 727713 US13354308 2012-01-19 US08592378B2 2013-11-26 Takanao Otsuka; Hirotsugu Ueda; Keiko Fujie; Hideyuki Muramatsu; Michizane Hashimoto; Shigehiro Takase
The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of the compound by culturing, in a culture medium, a WS727713-producing strain belonging to Pseudonocardia and recovering the compound from a culture broth, a pharmaceutical composition containing the compound, and uses of the compound.
143 Plant-derived natural biodegradable material US12516442 2007-11-26 US08349418B2 2013-01-08 Seiko Sato
It is intended to provide a natural biodegradable material having both properties of biodegradability and mechanical strength; a biodegradable film or container produced from the natural biodegradable material; a binder for producing the biodegradable material; and a method for producing these. A natural polymeric substance which has a cellulose-like property of having hydroxy group which is not present in a petroleum-derived polymeric compound, and which moreover has a polypropylene-like structure is obtained by the steps of using a cereal starch such as Kaoliang starch as a culture raw material, adding a microorganism belonging to the genus Bacillus to the raw material to conduct a culture, and recovering a viscous polymeric substance. A biodegradable material having biodegradability comparable to that of cellulose and also having a mechanical strength property of polypropylene can be obtained by using the natural polymeric substance as a binder and mixing starch and/or shell powder thereto. A film or container produced by using this biodegradable material has superior properties in both biodegradability and mechanical strength.
144 COMPOUND WS 727713 US13354308 2012-01-19 US20120214731A1 2012-08-23 Takanao Otsuka; Hirotsugu Ueda; Keiko Fujie; Hideyuki Muramatsu; Michizane Hashimoto; Shigehiro Takase
The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of the compound by culturing, in a culture medium, a WS727713-producing strain belonging to Pseudonocardia and recovering the compound from a culture broth, a pharmaceutical composition containing the compound, and uses of the compound.
145 Compound WS 727713 US12757684 2010-04-09 US08133713B2 2012-03-13 Takanao Otsuka; Hirotsugu Ueda; Keiko Fujie; Hideyuki Muramatsu; Michizane Hashimoto; Shigehiro Takase
The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of the compound by culturing, in a culture medium, a WS727713-producing strain belonging to Pseudonocardia and recovering the compound from a culture broth, a pharmaceutical composition containing the compound, a use of the compound for manufacture of a medicament or a cosmetic for melanocortin receptor modulation, a use of the compound for manufacture of a medicament or a cosmetic for treating or preventing ishemia/reperfusion injury, brain and renal inflammatory diseases, hepatitis, sepsis/septic shock, hypoxic shock, acute respiratory distress syndrome (ARDS), rheumatic arthritis (RA), gouty arthritis, aortic regurgitation (AR), juvenile chronic arthritis, osteoarthritis, nephritis, induction of tolerance, contact hypersensitivity, inflammatory bowel disease (IBD), sexual dysfuntion, transplantation, pain, disease progression of HIV, postinflammatory hypopigmentation, tinea versicolor, idiopathic guttate hypomelanosis, fever, functional bowel disease, obesity, satiety effect, diabetes mellitus, modulation of dermal exocrine function, canities (canities circumscripta), gray hair, pancreatitis, fibrotic disorders (hypertrophic scars, keloids, localized scleroderma, systematic sclerosis, sclerodermic graft versus host disease of the skin, cirrhosis of the liver, idiopathic and bleomycin induced lung fibrosis, cyclosporin induced nephropathy), uveitis (especially in Behçet's syndrome and sarcoidosis), vasculitis, microbial infections, celiac disease, vulvar vestibulitis syndrome, melonozna invasion, anorexia or the like.
146 COMPOUND WS 727713 US12757684 2010-04-09 US20100297735A1 2010-11-25 Takanao Otsuka; Hirotsugu Ueda; Keiko Fujie; Hideyuki Muramatsu; Michizane Hashimoto; Shigehiro Takase
The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of the compound by culturing, in a culture medium, a WS727713-producing strain belonging to Pseudonocardia and recovering the compound from a culture broth, a pharmaceutical composition containing the compound, a use of the compound for manufacture of a medicament or a cosmetic for melanocortin receptor modulation, a use of the compound for manufacture of a medicament or a cosmetic for treating or preventing ishemia/reperfusion injury, brain and renal infammatory diseases, hepatitis, sepsis/septic shock, hypoxic shock, acute respiratory distress syndrome (ARDS), rheumatic arthritis (RA), gouty arthritis, aortic regurgitation (AR), juvenile chronic arthritis, osteoarthritis, nephritis, induction of tolerance, contact hypersensitivity, inflammatory bowel disease (IBD), sexual dysfuntion, transplantation, pain, disease progression of HIV, postinflammatory hypopigmentation, tinea versicolor, idiopathic guttate hypomelanosis, fever, functional bowel disease, obesity, satiety effect, diabetes mellitus, modulation of dermal exocrine function, canities (canities circumscripta), gray hair, pancreatitis, fibrotic disorders (hypertrophic scars, keloids, localized scleroderma, systematic sclerosis, sclerodermic graft versus host disease of the skin, cirrhosis of the liver, idiopathic and bleomycin induced lung fibrosis, cyclosporin induced nephropathy), uveitis (especially in Behçet's syndrome and sarcoidosis), vasculitis, microbial infections, celiac disease, vulvar vestibulitis syndrome, melonozna invasion, anorexia or the like.
147 Adjuvant composition for use with herbicides, pesticides, insecticides, ovicides and fungicides and method of application US11984029 2007-11-13 US20080070787A1 2008-03-20 Erroll Pullen
An adjuvant for use with systemic herbicides, pesticides, insecticides, ovicides and fungicides and method of application on animals, birds, trees, plants, fruits and vegetables to enhance the action and effect of systemic herbicides, pesticides, insecticides, ovicides and fungicides with which the adjuvant is combined wherein the adjuvant comprises at least one surfactant and at least one high terpene containing natural oil.
148 Process for producing hop glume polyphenol US10538790 2003-12-12 US20060251760A1 2006-11-09 Motoyuki Tagashira; Tomomasa Kanda
It is intended to provide a process for efficiently producing highly purified hop bract polyphenol using hop bract as the starting material, and foods, drinks, cosmetics and drugs with the use of the highly purified hop bract polyphenol. Namely, a process for producing hop polyphenol which comprises extracting hop bract with an aqueous alcohol solution, concentrating the extract to give a residual alcohol concentration of 0.5 to 2% and then centrifuging and/or filtering the concentrate. This polyphenol is usable in foods, drinks, cosmetics, drugs, etc.
149 Antiprotozal composition US11391188 2006-03-28 US20060193834A1 2006-08-31 William Julien
A composition, and method of use, for controlling, reducing or preventing the growth of protozoal bacteria in the ruman of a rumiant comprising cell bodies of a facultative anaerobe selected from the group consisting of Corynebacterium cell bodies and Brevibacterium cell bodies or a mixture of Corynebacterium cell bodies and Brevibacterium cell bodies, glutamic acid fermention solubles, corn fermentation solubles, glutamic acid fermentation solubles and corn fermentation solubles.
150 Adjuvant composition for use with herbicides, pesticides, insecticides, ovicides and fungicides and method of application US10641823 2003-08-16 US20040242428A1 2004-12-02 Erroll M. Pullen
An adjuvant for use with systemic herbicides, pesticides, insecticides, ovicides and fungicides and method of application on animals, birds, trees, plants, fruits and vegetables to enhance the action and effect of systemic herbicides, pesticides, insecticides, ovicides and fungicides with which the adjuvant is combined wherein the adjuvant comprises at least one surfactant and at least one high terpene containing natural oil.
151 Controlling dust mites with a composition containing surfactants, high terpene oil and monohydric alcohol US09587595 2000-06-05 US06500445B1 2002-12-31 Erroll M. Pullen
Methods and compositions are provided for treating clothing, pillows, bedding, furniture, rugs or carpets for dust mites. Non-toxic aqueous compositions contain one or more surfactants high terpene oils and a monohydric alcohol. Various percentage weight amounts such as 17 to 27 percent of surfactants, 8 to 16 percent of high terpene oils, 4 to 8 percent monohydric and water are comprised by a composition for treating and controlling dust mites on clothing, pillows, bedding, furniture, rugs or carpets. A method for controlling and treating dust mites includes applying an effective amount of a non-toxic aqueous composition, scrubbing the composition into the clothing, pillows, bedding, furniture, rugs or carpets and rinsing the composition and dust mites therefrom.
152 Method of manufacturing a sterol ester mixture US09202899 2000-01-18 US06492538B1 2002-12-10 Marnix P van Amerongen; Lourus Cornelis Lievense; Cornelis Willem Van Oosten
Process for the manufacture of a mixture of fatty acid esters comprising the steps of: (a) hydrolysing a sterol ester or a mixture of sterol esters such that a mixture is obtained comprising phenolic acids and/or fatty acids, and free sterols; and (b) optionally, separating the phenolic acids and/or fatty from the reaction mixture; and (c) esterifying the so obtained free sterols with particular fatty acids.
153 Antiprotozal composition US10151126 2002-05-18 US20020176904A1 2002-11-28 William E. Julien
A composition, and method of use, for controlling, reducing or preventing the growth of protozoal bacteria in the ruman of a rumiant comprising cell bodies of a facultative anaerobe selected from the group consisting of Corynebacterium cell bodies and Brevibacterium cell bodies or a mixture of Corynebacterium cell bodies and Brevibacterium cell bodies, glutamic acid fermention solubles, corn fermentation solubles, glutamic acid fermentation solubles and corn fermentation solubles.
154 Calcium overbased metal-containing detergents US09180436 1998-11-09 US06429179B1 2002-08-06 Philip Skinner; Alain Louis Pierre Lenack
Phenate detergents and salicylate detergents with high TBNs and/or high TBN: % surfactant ratios are useful marine diesel lubricant additives.
155 Assimilation of inorganic selenium and organic germanium by yeast US09298114 1999-04-23 US06368643B1 2002-04-09 David Fan; Ping Yang; Houn Simon Hsia
The yeast, Saccharomyces boulardii, has been used to invent a non-toxic selenium-germanium yeast product. Culture growth conditions can influence the biosorbent selenium and germanium uptake capacity. The invention involves assimilation of selenium and germanium by the yeast under optimal conditions of incubation time, biomass concentration, reaction pH, reaction medium, and feed rate. This yeast can assimilate higher intracellular selenium and germanium by either a one-step continuous feed-batch fermentation or a two-step continuous and semi-continuous feed-batch fermentation. The invention additionally involves the novel germanium and selenium-containing yeast.
156 Process for isolating saponins from soybean-derived materials US09723350 2000-11-27 US06355816B1 2002-03-12 Thomas Dobbins
This invention uses acetone/water mixtures at various concnetration and temperatures as a cost effective method for recoveing soy saponins of high purity from soybean-derived materials, while also affording an economical means of recovering soy isoflavones as a by-product.
157 Type II phospholipase A2 and its use in killing Gram-positive bacteria US09232782 1999-01-19 US06280726B1 2001-08-28 Yvette Weinrauch; Peter Elsbach; Jerrold Weiss
Disclosed herein are methods for killing Gram-positive bacterial infections in animals comprising exposing the bacteria to Gram-positive bactericidal-effective amounts of Type II phospholipase A2. The Type II phospholipase A2 can be isolated from mammalian species including humans, cows, rabbits, rats, mice, cats, and dogs. Type II phospholipase A2 is effective in treating infections in mammals, including humans, caused by gram-positive bacteria such as Staphylococcus aureus. Also disclosed are pharmaceutical formulations for use in the methods.
158 Non-toxic aqueous pesticide US09282963 1999-03-31 US06258369B1 2001-07-10 Erroll M. Pullen
A non-toxic aqueous pesticide for application on plants and animals comprising at least one surfactant and at least one high terpene containing natural oil. The pesticide is used to effectively control insects and parasites such as lice, ticks, mites, aphides and chiggers found on plants and animals.
159 Dietary supplementation with, and methods for administration of yeast-derived selenium product US09303993 1999-05-03 US06197295B1 2001-03-06 Houn Simon Hsia; Ping Yang; Michael Arnold
The present invention solves the need for non-toxic forms of selenium which is an essential part of the human diet. This invention provides novel dried-yeast products containing selenium as well as a method of producing the dried yeast products. The method uses selenium having high biological activity but low toxicity. The invention also provides nutritional supplements containing the novel selenium containing dried yeast products and methods of administering these products and supplements to improve human health. The invention also provides a practically non-toxic yeast selenium product having increased intracellular selenium concentrations and methods to reduce tumor cell growth by administration of a selenium yeast product comprising yeast Saccharomyces boulardii sequela PY 31 (ATCC 74366) in combination with chemotherapeutic agents.
160 Ammonium thiosulfate complex of gold or silver and an amine US09299339 1999-04-26 US06197214B1 2001-03-06 Michael J. Virnig; J. Michael Sierakoski
The process of recovering precious metals from ores containing precious metals, such as gold and silver, from an aqueous ammoniacal thiosulfate leach solution to provide a significant practical and economical process for the recovery of gold or silver. After leaching of the ore with an aqueous ammoniacal thiosulfate solution, the leach solution is contacted with a precious metal extraction reagent to extract the precious metal values from the leach solution, after which the precious metal values are stripped from the extraction reagent to form a concentrated solution of the precious metal values from which the precious metals may be recovered by conventional methods such as electrolysis. The extraction reagents are those having guanidyl functionality or a quaternary amine functionality mixed with a weak organic acid such as a phenol. In the process, novel thiosulfate complexes of the precious metals are formed with the quanidyl or the quaternary amine extractants.
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