| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 201 | Cold plasma electroporation of medication and associated methods | US15376289 | 2016-12-12 | US09861829B2 | 2018-01-09 | Marc C. Jacofsky; David J. Jacofsky; Gregory A. Watson |
| A method and device to apply a cold plasma to a substance at a treatment surface of a patient to cause electroporation of the substance into cells of the patient. The substance can be previously applied to the treatment surface. Alternatively, the substance can be placed in a foam-like material within a tip that passes the cold plasma from the cold plasma device to the treatment area. The tip can be a cannula device with an aperture at the distal end. The cannula device can also have apertures along a portion of the length of the cannula device. | ||||||
| 202 | Liquid type plasma for preventing or treating cancer | US14982948 | 2015-12-29 | US09750951B2 | 2017-09-05 | Chul Ho Kim; Sun Yong Kim |
| The present invention relates to a method for preparing a plasma for preventing or treating a cancer. Also, the present invention relates to a liquid type plasma for preventing or treating a cancer prepared by treating the plasma and a pharmaceutical composition for preventing or treating a cancer comprising the same. The plasma and the liquid type plasma according to the present invention can effectively induce cancer cell death without a surgical operation or in a treatment process after a surgical operation, thereby being useful as a novel therapeutic agent and method for a cancer. | ||||||
| 203 | A NON-EQUILIBRIUM PLASMA SYSTEM AND METHOD OF REFINING SYNGAS | US15515222 | 2015-09-30 | US20170231078A1 | 2017-08-10 | Islam GOMAA; Andreas TSANGARIS; Graeme HAY |
| An object of the present invention is to provide a non-equilibrium plasma (NEP) system and method of refining syngas. In accordance with an aspect of the present invention, there is provided a non-equilibrium plasma system for refining syngas, the system comprising a reactor with a hollow chamber, having one or more inlet manifolds configured to promote an axially symmetric and swirling flow pattern, into which syngas and one or more gasifying agents are introduced for processing within the reactor, a high voltage electrode; and a ground electrode, wherein the system is configured to create a non-equilibrium plasma producing electric arc upon application of a high voltage potential across an arc initiating gap between the high voltage electrode and the ground electrode and wherein the system is configured such that the syngas, the one or more gasifying agent(s) and plasma producing electric arc come together concurrently in the reactor. In one embodiment of the invention, the non-equilibrium plasma system comprises two eccentric cylindrical manifolds configured to form a single inlet manifold, wherein the two eccentric cylindrical manifolds comprise a first eccentric cylindrical manifold for gasifying agent input and a second eccentric cylindrical manifold for syngas input. The invention also comprises a method for refining syngas wherein the non-equilibrium plasma system of the present invention combines the syngas, the air and the plasma-producing electric arc in the same region, which will co-exist in the same location. | ||||||
| 204 | Cold Plasma Treatment Devices and Associated Methods | US15431208 | 2017-02-13 | US20170156200A1 | 2017-06-01 | Gregory A. Watson; Robert M. Hummel; Marc C. Jacofsky; David J. Jacofsky |
| A compact cold plasma device for generating cold plasma having temperatures in the range 65 to 120 degrees Fahrenheit. The compact cold plasma device has a magnet-free configuration and an induction-grid-free configuration. An additional configuration uses an induction grid in place of the input electrode to generate the cold plasma. A high voltage power supply is provided that includes a controllable switch to release energy from a capacitor bank to a dual resonance RF transformer. A controller adjusts the energy input to the capacitor bank, as well as the trigger to the controllable switch. | ||||||
| 205 | Cold Plasma Treatment Devices and Associated Methods | US15419427 | 2017-01-30 | US20170136253A1 | 2017-05-18 | Gregory A. Watson; Marc C. Jacofsky |
| A cold plasma treatment device for delivery of a cold plasma to patient treatment area. Gas is fed to a gas compartment where it is energized by an electrode coupled to a pulse source to thereby generate a cold plasma. A dielectric barrier is sandwiched between the gas compartment and the electrode to form a dielectric barrier discharge device. The cold plasma exits the gas compartment via a bottom member having a plurality of holes. Gases that can be used include noble gases such as helium or combinations of noble gases. | ||||||
| 206 | Cold plasma treatment devices and associated methods | US14685080 | 2015-04-13 | US09570273B2 | 2017-02-14 | Gregory A. Watson; Robert M. Hummel; Marc C. Jacofsky; David J. Jacofsky |
| A compact cold plasma device for generating cold plasma having temperatures in the range 65 to 120 degrees Fahrenheit. The compact cold plasma device has a magnet-free configuration and an induction-grid-free configuration. An additional configuration uses an induction grid in place of the input electrode to generate the cold plasma. A high voltage power supply is provided that includes a controllable switch to release energy from a capacitor bank to a dual resonance RF transformer. A controller adjusts the energy input to the capacitor bank, as well as the trigger to the controllable switch. | ||||||
| 207 | NON-THERMAL PLASMA | US15112699 | 2015-01-22 | US20160338755A1 | 2016-11-24 | Thomas Bickford Holbeche; Rodney Stewart Mason |
| A plasma-generation device for applying plasma to a human body, having a reservoir containing a gas, a plasma zone in fluid connection with the reservoir, and means for generating a plasma by electrical discharge in the plasma zone. The gas has a composition of 92% to 99.9% Argon and 0.1% to 8% Krypton; or 95% to 99.5% Argon and 0.5% to 5% Hydrogen; or 92% to 99.5% Argon and 0.5% to 8% Nitrous Oxide. | ||||||
| 208 | COLD PLASMA JET HAND SANITIZER | US15191565 | 2016-06-24 | US20160307735A1 | 2016-10-20 | Gregory A. Konesky |
| A cold plasma jet hand sanitizer and method of use are provided. A pair of opposing two-dimensional arrays of atmospheric pressure cold plasma jets is used to create a sterilizing volume. Any object placed into that volume will have its surface sterilized. The opposing arrays of plasma jets are operated electrically 180 degrees out of phase so that the opposing arrays of plasma jets essentially fire into each other in the absence of an intervening object, or directly impinge on the surface of an intervening object. | ||||||
| 209 | Process for the Treatment of Fruits and Vegetables | US15032856 | 2014-10-28 | US20160262410A1 | 2016-09-15 | Johannes Adrianus Maria Hoefnagels |
| The present invention is directed to a process for the treatment of fruits and/or vegetables, and especially for the coating of pomes, such as apples and pears. Particularly, fruits and/or vegetables are treated with a physical treatment and particularly a cold plasma treatment, optionally followed by another treatment. The terms “fruits” and “vegetables” are used in accordance with the present invention in broad sense and comprise all kinds of edible products of nature including fruits in the botanical sense, pomes, pseudo carps, tubers, bulbs, greens, cabbages etc. | ||||||
| 210 | BOOSTING THE EFFICACY OF DNA-BASED VACCINES WITH NON-THERMAL DBD PLASMA | US15012304 | 2016-02-01 | US20160220670A1 | 2016-08-04 | Sameer Kalghatgi; Daphne Pappas Antonakas; Tsung-Chan Tsai; Robert L. Gray; Sarah D. Stone |
| The efficacy of a DNA-based vaccine in terms of eliciting a desired immune response is enhanced by directing a non-thermal plasma generated by a non-thermal plasma generator at the site on the patient's skin where the vaccine was previously introduced. | ||||||
| 211 | Cold plasma jet hand sanitizer | US13802063 | 2013-03-13 | US09387269B2 | 2016-07-12 | Gregory A. Konesky |
| A cold plasma jet hand sanitizer and method of use are provided. A pair of opposing two-dimensional arrays of atmospheric pressure cold plasma jets is used to create a sterilizing volume. Any object placed into that volume will have its surface sterilized. The opposing arrays of plasma jets are operated electrically 180 degrees out of phase so that the opposing arrays of plasma jets essentially fire into each other in the absence of an intervening object, or directly impinge on the surface of an intervening object. | ||||||
| 212 | METHODS AND APPARATUS FOR DELIVERY OF MOLECULES ACROSS LAYERS OF TISSUE | US14959405 | 2015-12-04 | US20160089545A1 | 2016-03-31 | Abhishek Juluri; Sameer Kalghatgi; Robert L. Gray |
| Exemplary methods of opening pores and moving molecules into tissue comprising, applying plasma to the surface of tissue and applying a carrier including one or more molecules to the surface of the tissue are disclosed herein. | ||||||
| 213 | Device for generating gaseous species | US14265463 | 2014-04-30 | US09295535B2 | 2016-03-29 | Thomas Bickford Holbeche; Cormac John Devery; Geoffrey Morgan Lloyd |
| The present invention provides a device for generating a non-thermal gas species which may be a flow of gas plasma in the form of a gas plasma plume emitted from the device. The device comprises a gas capsule, or pressure vessel for holding a gas or gases under pressure and forming a flow of gas through a reaction generator to an applicator when released from the capsule. Gas released from the gas capsule is energised in the reaction generator to form the gas plasma. The device is designed to be hand held and hand operated so that it may be used for cleaning and whitening teeth as well as other applications. | ||||||
| 214 | Harmonic cold plasma devices and associated methods | US13620132 | 2012-09-14 | US09257264B2 | 2016-02-09 | Robert M. Hummel; Gregory A. Watson; Marc C. Jacofsky; David J. Jacofsky |
| A gas cartridge is described that is configured to provide sufficient gas to support cold plasma generation for a specific medical process. The gas cartridge has a seal that is pierced upon connection of the gas cartridge to the cold plasma delivery system. Different embodiments are described that use different connection locations between the gas cartridge and the cold plasma delivery system. A shroud is also described that shields the user if the cold plasma delivery system is dropped and the gas cartridge ruptures. Use of an ID system assists in ensuring that the correct gas mixture, correct gas cartridge and correct power supply settings are used for the particular medical treatment process. | ||||||
| 215 | APPARATUS AND METHOD FOR TREATING BIOLOGICAL TISSUE USING LOW-PRESSUE PLASMA | US14424954 | 2013-06-20 | US20160030760A1 | 2016-02-04 | Josef Srb; Josef Korous; Jan Hinterkopf |
| The invention relates to apparatus for treating biological tissue (G) using a low-pressure plasma with a) a transformer (1) for generating a high-frequency electromagnetic field, b) a probe, which can be electrically coupled to the transformer (1) and c) a control device (3) for controlling the high-frequency electromagnetic field generated by the transformer (1), wherein the transformer (1) has a primary coil (4) and a secondary coil (5) disposed coaxially therewith and wherein the intermediate space between the primary coil (4) and the secondary coil (5) in the overlap region (B) of the two coils (4, 5) increases from a first spacing (d1) to a second, greater spacing (d2) in the direction of a coupling (7) for the probe (2). | ||||||
| 216 | METHOD FOR CONTROLLING BIOLOGICAL PROCESSES IN MICROORGANISMS | US14875864 | 2015-10-06 | US20160023183A1 | 2016-01-28 | Tamar LEVIN |
| The present invention discloses a method for providing at least one biological effect in at least one microorganism. The aforementioned method comprises steps of: (a) providing a system for administering modified plasma; (b) providing a substrate hosting said at least one microorganism; and (c) administering the generated modified plasma beam in a predetermined pulsed manner to said substrate hosting said at least one microorganism to provide said at least one biological effect to said at least one microorganism. The present invention further provides a system thereof. | ||||||
| 217 | Cold plasma treatment devices and associated methods | US13620205 | 2012-09-14 | US09236227B2 | 2016-01-12 | Gregory A. Watson; Marc C. Jacofsky |
| An inhalable cold plasma mask device for generation of a breathable cold plasma for delivery to a patient. A biocompatible gas is received in a dielectric barrier discharge (DBD) device that is energized by an electrode that receives energy from a pulsed source. The DBD device can be grounded by a grounding structure. A grounding screen can be used prior to inhalation of the cold plasma. The inhalable cold plasma mask device includes the use of a single-layer or a two-layer approach to its construction. The inhalable cold plasma mask device can have one or two DBD devices. Such a device and associated method can be used to treat upper respiratory tract infections, as well as reducing inflammation, sinus and esophageal polyps in both size and frequency of occurrence. | ||||||
| 218 | Harmonic cold plasma devices and associated methods | US13620236 | 2012-09-14 | US09192776B2 | 2015-11-24 | Robert M. Hummel; Gregory A. Watson; Marc C. Jacofsky; David J. Jacofsky |
| A nozzle for attachment to a cold plasma device configured to maintain delivery of a stable cold plasma. The nozzle can have many different shaped apertures to support different applications requiring different shaped cold plasma plumes. Use of a disc of foam material within a nozzle can expand the size of aperture of a nozzle while maintaining delivery of a stable cold plasma. The nozzle can be an elongated cannula tube for internal delivery of a cold plasma treatment. The cannula tube can provide an aperture at its distal end or one or more apertures along its length. A shroud can partially enclose the distal aperture of the nozzle. A sterile sleeve can be used in conjunction with a nozzle to provide a sterile means of attachment and operation of the nozzle with a cold plasma device. | ||||||
| 219 | Device for providing a flow of active gas | US13083699 | 2011-04-11 | US09072157B2 | 2015-06-30 | Thomas Bickford Holbeche; Richard Thomas Reich; Peter Dobson; Cormac John Devery; Andrew Richard Thomas Tatarek |
| A device 10, typically hand-held, provides a flow of partially ionized gaseous plasma for treatment of a treatment region. The device comprises an applicator head 52 housing a miniature plasma cell 16 in which gas flowing through the cell from a gas source 22 can be energized to form a non-thermal gaseous plasma, and a plurality of electrodes 26, 28 for receiving electrical energy from a source of electrical energy for energizing gas in a plasma forming region 18 in the cell to form said plasma. The applicator head 52 is detachable from the device and may be of a size and configuration to enable it to be inserted into the oral cavity of a human or animal. | ||||||
| 220 | PLASMA TREATMENT DEVICE | US14395911 | 2013-04-24 | US20150132711A1 | 2015-05-14 | Rodney Stewart Mason |
| A plasma treatment device comprises a body portion housing a battery, a gas cylinder, a power supply circuit and a plasma generator comprising a pair of electrodes. The device includes a detachable applicator portion and an elongate duct extending from the generator to convey generated plasma to an outlet of the duct and for directing a plasma plume formed at the outlet onto a treatment area. An annular electrode is disposed at the duct outlet and is connected to the power supply circuit via an elongate electrical conductor. The annular electrode conducts electrons in the plasma away from the plasma plume to avoid sensation caused by resultant current flow. A circuit may be provided to measure the current flow from the annular electrode, the circuit allowing adjustment of the power supplied to the pair of electrodes based on the measured current. | ||||||
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