INFLUENZA M2 PROTEIN MUTANT VIRUSES AS LIVE INFLUENZA ATTENUATED VACCINES |
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| 申请号 | PCT/US2008007582 | 申请日 | 2008-06-18 | 公开(公告)号 | WO2008156778A2 | 公开(公告)日 | 2008-12-24 |
| 申请人 | WATANABE TOKIKO; KAWAOKA YOSHIHIRO; | 发明人 | WATANABE TOKIKO; KAWAOKA YOSHIHIRO; | ||||
| 摘要 | A method to prepare recombinant influenza viruses comprising a mutant M2 protein which has a deletion of two or more residues in the cytoplasmic tail and is attenuated in vivo, is provided, as well the resulting virus and vaccines with the virus. | ||||||
| 权利要求 | |||||||
| 说明书全文 | |||||||
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