序号 | 专利名 | 申请号 | 申请日 | 公开(公告)号 | 公开(公告)日 | 发明人 |
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121 | CELL STORAGE METHOD AND USE THEREOF FOR CELL TRANSPORT | EP09821833.2 | 2009-10-23 | EP2345714B1 | 2018-09-12 | ITCHODA, Yoko; TAZAKI, Go; FUKUDA, Motohiro; TSURUTA, Hitoshi; TANIGUCHI, Hideki |
To provide a cell storage method to store living cells while maintaining the functions of the living cells. An aspect of the cell storage method is a method to store living cells (40) by using a cell culture chamber (20) including a plurality of the microchambers (11), the method including: culturing the living cells by being adhered to the surfaces of a plurality of micro spaces; and after the culturing, pouring the culture medium (50) into the cell culture chamber (20) so as to cover the plurality of microchambers (11), and storing the living cells. The living cells are adhered to a cell culture chamber of an appropriate size and cultured to form a three-dimensional structure. This enables maintaining the three-dimensional structure of the living cells and storage of the living cells while maintaining the functions thereof. | ||||||
122 | MANUFACTURING ARTICLE | EP15792577 | 2015-05-15 | EP3143120A4 | 2018-02-28 | SNYDER MITCHELL L; ZOELLNER CLEMENS E; NIXON THOMAS R |
A manufacturing article adapted for use in the production of pharmaceuticals comprising a tray comprising a base having a top surface; and a manifold extending from the top surface of the base, the manifold comprising a sidewall and an upper surface, the upper surface further comprising a channel, wherein, when viewed from the top surface, the base has an area, AB, the upper surface of the manifold has an area AM, and AB>AM, and wherein the base is adapted to support a plurality of vessels each adapted to contain a fluid. | ||||||
123 | HEPATOCYTE CULTURE DEVICE CAPABLE OF ENHANCING ACCUMULATION AND EXCRETION OF HEPATIC METABOLITE IN AND INTO BILE CANALICULUS-LIKE STRUCTURE, AND METHOD FOR EVALUATING CANDIDATE COMPOUND SENSITIVE TO EXCRETION INTO BILE OR BLOOD AND HEPATIC METABOLITE OF SAID CANDIDATE COMPOUND USING SAID HEPATOCYTE CULTURE DEVICE | EP16772300.6 | 2016-03-16 | EP3275994A1 | 2018-01-31 | TAKEZAWA, Toshiaki |
The present invention is a hepatocyte culture device enhancing accumulation and excretion of a hepatic metabolite in and into a bile canaliculus-like structure, the device including: a first cell culture containing a plurality of hepatocytes; a portable culture vessel in which the bile canaliculus-like structure can be established between the hepatocytes in the first cell culture, and that has, on an outer surface of the culture vessel, a membrane through which a physiologically active substance can pass; and a second cell culture capable of improving excretion activity of a hepatic metabolite in the first cell culture, in which the first cell culture cultured in the portable culture vessel is disposed on the second cell culture to be co-cultured. |
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124 | FOLIENSYSTEM ZUM BEREITSTELLEN EINES BIOREAKTORS UND ZUGEHÖRIGE FOLIENSYSTEMROLLE SOWIE VERFAHREN ZUM HERSTELLEN EINES BIOREAKTORS, BIOREAKTOR UND BIOREAKTORSYSTEM | EP11716462.4 | 2011-02-14 | EP2536816B1 | 2018-01-10 | THOMSEN, Claudia |
125 | CELL CULTURE CARRIER | EP12860052 | 2012-11-27 | EP2796537A4 | 2015-08-12 | YORI KOUICHIROU |
A cell culture transferring instrument (10) includes a cylindrical body (12) held by an operator not shown in the drawing, a plunger (14) inserted through the interior of the cylindrical body (12), a plurality of support members (16) connected to a distal end (14a) of the plunger (14), and an adsorbent (20) capable of adsorbing a sheet-shaped cell culture (18) held by the support members (16). The support members (16) in contact with the distal end of the cylindrical body (12) are elastically deformed by displacing the plunger (14) toward the proximal end (14b) side with respect to the cylindrical body (12) in a state in which the sheet-shaped cell culture (18) is adsorbed to the adsorbent (20), whereby the adsorbent (20) and the sheet-shaped cell culture (18) are deformed and housed in a housing hole (22) in the cylindrical body (12). | ||||||
126 | BEHAELTNIS ZUR AUFNAHME VON NAEHRMEDIEN | EP14709539.2 | 2014-01-24 | EP2812423A1 | 2014-12-17 | MUELLER, Rolf |
The invention relates to a container for accommodating nutrient media (3), in particular a Petri dish, contact plate, or sedimentation plate, for cultivating microorganisms, cell cultures, bacteria, etc. comprising a main body (1), which has a peripheral wall (4), and a bottom plate (2), and a base surface (1) which has a peripheral wall. The main body (1) and the bottom plate (2) form a dish. The dish is used for filling with nutrient solution, for storage, and for transport. The main body (1) is placed or inserted into the peripheral wall of the bottom plate (6) with at least a slight distance from the base surface of the bottom plate (5). On the side facing away from the bottom plate (2), the main body (1) has a closure, which is attached after the main body (1) has been filled with nutrient medium (3) and closes the main body (1) containing the nutrient medium (3). | ||||||
127 | DEVICE AND METHOD FOR BACTERIAL CULTURE AND ASSAY | EP12844273.8 | 2012-10-29 | EP2771456A1 | 2014-09-03 | DERDA, Ratmir; FUNES HUACCA, Maribel Elizabeth; NG, Simon; TJHUNG, Katrina Felicia |
The present invention provides a simple culture device that is designed for manufacture and use in areas of limited resources. The device is useful for cell culture in such environments with limited resources because cells grow in paper just as they do in a culture dish. Also provided is a binding assay that employs an activatable dormant bacteriophage carrying a reporter gene to qualitatively or quantitatively detect the presence of a substance of interest in a sample. | ||||||
128 | INKUBATOREINRICHTUNG UND VERFAHREN ZU DEREN BETRIEB | EP11711462.9 | 2011-03-23 | EP2550349A2 | 2013-01-30 | RAPOPORT, Daniel; KRUSE, Charli; WENDT, Dennis |
A movable incubator facility comprises a culture chamber which is arranged for receiving at least one cell culture, a heating arrangement by means of which the temperature of the culture chamber can be adjusted, a gas feed arrangement by means of which at least one gas can be introduced into the culture chamber, and an energy storage arrangement which is disposed for supplying the heating arrangement and/or the gas feed arrangement with electrical energy. | ||||||
129 | FOLIENSYSTEM ZUM BEREITSTELLEN EINES BIOREAKTORS UND ZUGEHÖRIGE FOLIENSYSTEMROLLE SOWIE VERFAHREN ZUM HERSTELLEN EINES BIOREAKTORS, BIOREAKTOR UND BIOREAKTORSYSTEM | EP11716462.4 | 2011-02-14 | EP2536816A1 | 2012-12-26 | THOMSEN, Claudia |
Algae are grown under autotrophic and mixotrophic cultivation conditions in photobioreactors and produced in large quantities. Film systems that are in particular flexible are used to produce photobioreactors. Said flexible film systems are delivered in standard sizes that cannot be adapted by users to in situ conditions or are difficult to adapt to said conditions. The solution proposed by the invention to this problem of prior art is a film system that is in particular designed to provide a bioreactor for cultivating photosynthetically active organisms and that consists of a transparent film material. The film system has two opposing inner faces with a separating connection that forms two separate regions and said separating connection is not continuous giving the two separate regions a first unhindered connection. | ||||||
130 | CELL STORAGE METHOD AND CELL TRANSPORT METHOD | EP09821833.2 | 2009-10-23 | EP2345714A1 | 2011-07-20 | ITCHODA, Yoko; TAZAKI, Go; FUKUDA, Motohiro; TSURUTA, Hitoshi; TANIGUCHI, Hideki |
To provide a cell storage method to store living cells while maintaining the functions of the living cells. An aspect of the cell storage method is a method to store living cells (40) by using a cell culture chamber (20) including a plurality of the microchambers (11), the method including: culturing the living cells by being adhered to the surfaces of a plurality of micro spaces; and after the culturing, pouring the culture medium (50) into the cell culture chamber (20) so as to cover the plurality of microchambers (11), and storing the living cells. The living cells are adhered to a cell culture chamber of an appropriate size and cultured to form a three-dimensional structure. This enables maintaining the three-dimensional structure of the living cells and storage of the living cells while maintaining the functions thereof. |
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131 | INCUBATOR FOR OBSERVATION BY MICROSCOPE | EP03791179 | 2003-03-26 | EP1548484A4 | 2009-08-26 | TSUCHIYA HIDEHARU |
An incubator capable of observing an observed specimen in a dish (220) by a microscope while cultivating the specimen, wherein light is radiated from a capacitor (C), passed through a hole (273) in a top plate (271), a hole (275a) in an upper side plate (275), and a hole (277a) in a lower side plate (277), and let into an objective lens (T), and the specimen put in the dish (220) is observed by the microscope, whereby the change of the specimen with elapse of time can be continuously observed or recorded on a videotape while cultivating the observed specimen in the dish (220). | ||||||
132 | Portable biotechnology kit | EP07380235.7 | 2007-08-09 | EP1890144A3 | 2008-07-02 | Martinez de Pancorbo; Rosique Sola, Melania Julieta; Ramos de Pablo, Rodrigo; Eguskiza Madariaga, Gaizka |
Portable biotechnology Kit which object is providing all the necessary material for the performance of laboratory practical lessons in an easy manner and at a low cost which basic structure is a group box containing all the material necessary for carrying out a microbial or molecular biotechnology practical lesson and wherein said group box consist of a flat sheet of cardboard, with folding lines that allow it to be turned into a closed container in which to transport all the material necessary for the practical but which once open, remains unfolded in a flat surface which can be used as a work surface. |
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133 | KLIMAKAMMER FÜR MIKROSKOPE | EP04765416.5 | 2004-09-20 | EP1575706A1 | 2005-09-21 | PIRSCH, Matthias; HUMMEL, Stefan |
The invention relates to a climatic chamber, which is in particular suitable for chemical and/or biological samples. Said chamber comprises a climatic compartment (26), which is formed by a housing (24). An analysis device (28), such as a microscope is located at least partially inside said climatic compartment (26). In addition, the housing (24) comprises an inlet (38) for supplying a stream (42) of conditioning medium. To prevent condensation forming on condensation-sensitive components (30, 32, 34) the medium stream (42) is positioned in such a way that it flows at least partially onto the analysis device (28) and/or the sample carrier (36). | ||||||
134 | INCUBATOR FOR OBSERVATION BY MICROSCOPE | EP03791179.9 | 2003-03-26 | EP1548484A1 | 2005-06-29 | TSUCHIYA, Hideharu |
An incubator capable of observing an observed specimen in a dish 220 by a microscope while culturing the specimen, wherein light is radiated from a capacitor(C), passed through a hole 273 in a top plate 271, a hole 275a in a upper side plate 275 and a hole 277a in a lower side plate 277, and let into an objective lens (T), and the specimen put in the dish 220 is observed by the microscope, whereby the change of the specimen with elapse of time can be continuously observed or recorded on a videotape while culturing the observed specimen in the dish 220. |
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135 | PROLIFERATION AND DELIVERY APPARATUS | EP03766051.1 | 2003-07-15 | EP1539918A1 | 2005-06-15 | HORN, Charles, Henry |
A portable, disposable, unitary microorganism proliferation and delivery apparatus (10) is provided. The apparatus (10) comprises a proliferation chamber (12) for containing a growth medium (14); and an inoculation chamber (16) for containing an inoculum (18). The proliferation and inoculation chambers (12 and 16) are connected by a tube (19) defining a passage (20), which is closed by a separating means in the form of a septum (22). The inoculation chamber (16) is provided or defined by a flexible vial having a mouth (16.1) and the septum (22) closes the mouth. Opening means in the form of a spike (24) is mounted in the passage (20) directed at the septum (22). The mouth (16.1) of the inoculation chamber (16) is connected to one end of the tube (19) by an advancement means in the form of a screw thread connection (26). | ||||||
136 | Device for detection of microorganisms in a sample | EP96103336.2 | 1996-03-04 | EP0730026B1 | 2002-06-12 | Benjamin Alspector c/o BATEC Ltd. |
137 | APPARATUS AND METHOD FOR MAINTAINING AND GROWING BIOLOGICAL CELLS | EP96921439.4 | 1996-06-07 | EP0832182B1 | 2001-08-16 | ARMSTRONG, R., Douglas; MALUTA, James; ROECKER, David, W. |
An apparatus and related method are disclosed, for receiving, maintaining and growing biological cells ex vivo within a portable cassette, without exposing the cells to the external environment. The portable cassette is used in combination with a processor instrument that facilitates an initial inoculation of the cassette with cells of the kind to be grown and to distribute those cells in a predeterminded pattern (e.g., uniformly) throughout a cell growth chamber. Thereafter, the portable cassette is used in combination with an incubator instrument that incubates the cell growth chamber so that the cells are optimally expanded. The same processor instrument then is used to harvest the expanded cells from the portable cassette. Both instruments are configured to condition the portable cassette during stages of the cell growth process, without disturbing the cassette's sterile system. In addition, an updatable memory device associated with the cassette stores significant information about the cassette and its condition during the various steps of the cell growth process. Such information is useful both for subsequent archival purposes and for facilitating a resumption of the cell growth process in the event of any instrument failure or significant alarm condition. | ||||||
138 | 미생물 수송배지 용기 | KR1020100069402 | 2010-07-19 | KR1020120008600A | 2012-02-01 | 박승범 |
PURPOSE: A microorganism transport container is provided to enhance a user's convenience and to improve sample collection efficiency. CONSTITUTION: A microorganism transport container(100) comprises: a collection rod(130) with a collection part(131) at one side; a head cap(110) which is fixed and coupled with the other side of the collection rod; a container(140) having a medium on a part of the collection part; and an anti-contact member(120) for preventing contact of the collection part with the medium. The head cap is coupled with one side of the container. | ||||||
139 | 검체수송용기 | KR1020100105724 | 2010-10-28 | KR1020100120278A | 2010-11-15 | 염성희 |
PURPOSE: A specimen container used for transferring and culturing specimen is provided to prevent leakage of reagent and to reduce inconvenience of opeining. CONSTITUTION: A specimen container comprises: a container(10); a specimen bar(20) having at least one penetration-inducing hole(25) inside; a brush or cotton swab(30) containing inside the container; a reagent container(40) having a closing thin film(41) at the lower end; the upper side(51) closing reagent storing space; a pressurizing cover(50) having a cutter(52); and the reagent storing space(53) inside the pressurizing cover. | ||||||
140 | 역류방지수단이 구비된 검체수송용기 | KR1020080073631 | 2008-07-28 | KR100987952B1 | 2010-10-18 | 염한림 |
본 발명은 역류방지수단이 구비된 검체수송용기에 관한 것으로, 더욱 구체적으로는 시약과 면봉을 각각 하나의 조립체인 커버에 포장 가능하면서도 내부의 역류방지수단에 의해서 시약이 면봉과 격리된 상태에서 저장되게 하여 면봉의 별도 밀봉 포장을 배제할 수 있게 하여 생산성과 검사자의 편의성을 향상시킬 수 있고, 또한 검체 채취 후에 간편한 조작에 의해서 시약이 면봉 측으로 유입되게 하며, 면봉에 유입된 시약이 역류방지수단에 의해서 다시 최초의 저장소인 커버 측으로 역류하지 않게 하여 검사의 정밀도와 신뢰성을 향상시킬 수 있는 검체수송용기를 제공할 목적으로, 연질의 유연성과 탄성이 있는 고무, 실리콘 또는 플라스틱 재료로 되고, 내향 함몰된 요홈(11)이 형성된 커버(10)와, 상단에 결속부(21)가 구비되고 상단이 개방된 본체(20)와, 상기 요홈의 내면과 접하는 실링부(31)가 형성된 밸브(30)와, 상기 커버(10)의 하부에 고정되되, 저부에 상기 본체의 결속부와 착탈 가능한 결합부(41)가 형성되고, 상기 본체 내로 삽입되는 채집부(44)를 포함하는 면봉(43)이 구비되며, 상하를 관통한 적어도 하나의 홀(42)이 구비된 채집기(40)로 구성되어, 상기 밸브가 커버 내의 시약(R)의 누설 또는 역류를 방지하도록 상기 커버(10)의 요홈(11)에 위치되는 검체수송용기가 개시된다. |