序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 Thrombin-free biological adhesive, and use thereof as medicament JP2012279119 2012-12-21 JP2013075906A 2013-04-25 CHTOUROU ABDESSATAR
PROBLEM TO BE SOLVED: To (1) provide a thrombin-free biological adhesive containing a blood coagulation factor not having a risk of forming fibrin before applying it on a biological tissue, and to (2) enable the production of such adhesive capable of increasing the hemostatic capability of injured tissue and further prompting the healing of connective tissue.SOLUTION: This stable, thrombin-free, fibrinogen-based, single-liquid-preparation biological adhesive used for treatment includes factor VIIa and a calcium ion source.
2 COLLE BIOLOGIQUE EXEMPTE DE THROMBINE ET SON UTILISATION COMME MEDICAMENT EP16162601.5 2006-12-15 EP3075387A1 2016-10-05 CHTOUROU, Abdessatar

L'invention concerne une colle biologique à base de fibrinogène, à usage thérapeutique, comprenant du facteur VIIa et une source d'ions calcium, et est exempte de thrombine. L'invention concerne également l'utilisation de la colle biologique comme médicament, notamment comme pansement pour les tissus biologiques, les plaies ou les biomatériaux.

3 MULTI-FUNCTIONAL PRIMER AND METHOD OF MANUFACTURING SHOE USING THE SAME EP10744903.5 2010-08-12 EP2467440B1 2014-03-05 HUH, Sung-Hwan
The present invention provides a multifunctional primer, comprising a first solution including 15 to 55 parts by weight of natural rubber and 750 to 1350 parts by weight of an organic solvent; a second solution from 100 parts by weight of the first solution and additionally 45 to 90 parts by weight of a polyurethane-dispersion; comprising a third solution from 100 parts by weight of the second solution and 100 to 250 parts by weight of a butadiene-based rubber solution containing 50 to 200 parts by weight of a butadiene rubber and 800 to 950 parts by weight of an organic solvent. Additionally a method of manufacturing a shoe is disclosed in an environmentally friendly manner by application of the primer to a transfer sheet, this being dried and cut into appropriate pieces, and this film-type multifunctional primer applied on a non-vulcanized outersole of a shoe.
4 THROMBIN-FREE BIOLOGICAL ADHESIVE AND USE THEREOF AS A MEDICAMENT US14812116 2015-07-29 US20150328362A1 2015-11-19 Abdessatar Chtourou
The invention relates to a thrombin-free, fibrinogen-based biological adhesive for therapeutic use, which comprises factor VIIa and a source of calcium ions. The invention also relates to the use of the biological adhesive as a medicament, in particular as a dressing for biological tissues, wounds or biomaterials.
5 THROMBIN-FREE BIOLOGICAL ADHESIVE AND USE THEREOF AS A MEDICAMENT US14812079 2015-07-29 US20150328291A1 2015-11-19 Abdessatar Chtourou
The invention relates to a thrombin-free, fibrinogen-based biological adhesive for therapeutic use, which comprises factor VIIa and a source of calcium ions. The invention also relates to the use of the biological adhesive as a medicament, in particular as a dressing for biological tissues, wounds or biomaterials.
6 FLUID ACTIVATABLE ADHESIVES FOR GLUE-FREE, LINER-FREE, LABELS FOR GLASS AND PLASTIC SUBSTRATES AND METHODS OF USE THEREOF US14491571 2014-09-19 US20150056441A1 2015-02-26 Daniel Cho; Heidi Munnelly; Benjamin Lux
Methods for applying a liner-free, or liner-less label, to a substrate, particularly glass or plastic (e.g., PET) substrates are described herein. The method includes applying an adhesive composition, such as a polymeric coating, to a label face sheet, activating the adhesive composition with an activating fluid, and contacting the label to the substrate. The activating fluid is preferably a mixture of water and one or more organic solvents, such as low molecular weight alcohols. In some embodiments, the labels exhibit a percent fiber tear greater than about 50, 55, 60, 65, 70, 75, 80, 85, 90, or 95% after one, two, three, four, or five minutes. In particular embodiments, the labels exhibits a percent fiber tear greater than 60, 65, 70, 75, 80, 85, 90, or 95% after two minutes.
7 Fluid activatable adhesive for glue-free, liner-free, labels for glass and plastic substrates and methods of use thereof US13738420 2013-01-10 US08840994B2 2014-09-23 Daniel Cho; David A. Sonshine; Heidi Munnelly; Benjamin Lux
Methods for applying a liner-free, or liner-less label, to a substrate, particularly glass or plastic (e.g., PET) substrates are described herein. The method includes applying an adhesive composition, such as a polymeric coating, to a label face sheet, activating the adhesive composition with an activating fluid, and contacting the label to the substrate. The activating fluid is preferably a mixture of water and one or more organic solvents, such as low molecular weight alcohols. In some embodiments, the labels exhibit a percent fiber tear greater than about 50, 55, 60, 65, 70, 75, 80, 85, 90, or 95% after one, two, three, four, or five minutes. In particular embodiments, the labels exhibits a percent fiber tear greater than 60, 65, 70, 75, 80, 85, 90, or 95% after two minutes.
8 Hybrid adhesive US12896905 2010-10-03 US08551287B2 2013-10-08 Rafael J. Zaldivar; James P. Nokes
A hybrid adhesive incorporating cyanate ester and/or epoxy materials and utilizing atmospheric plasma treatment provides stronger, more reliable joints in structural composite parts.
9 Multi-functional primer and method of manufacturing shoe using the same US13399238 2012-02-17 US08479336B2 2013-07-09 Sung-Hwan Huh
The present invention provides a multifunctional primer, comprising a first solution including 15 to 55 parts by weight of natural rubber and 750 to 1350 parts by weight of an organic solvent; a second solution from 100 parts by weight of the first solution and additionally 45 to 90 parts by weight of a polyurethane-dispersion; comprising a third solution from 100 parts by weight of the second solution and 100 to 250 parts by weight of a butadiene-based rubber solution containing 50 to 200 parts by weight of a butadiene rubber and 800 to 950 parts by weight of an organic solvent. Additionally a method of manufacturing a shoe is disclosed in an environmentally friendly manner by application of the primer to a transfer sheet, this being dried and cut into appropriate pieces, and this film-type multifunctional primer applied on a non-vulcanized outersole of a shoe.
10 USE OF SILANES AS ADHESION PROMOTERS BETWEEN TWO ORGANIC SURFACES US12595067 2008-04-24 US20100147451A1 2010-06-17 Ramon Sanchez Morillo
The use of silanes as adhesion promoters between two uncured or partially cured organic surfaces, especially such surfaces that do not adhere well to each other, and particular applications of such silanes, such as in the formation of boat hull laminates.
11 MULTI-FUNCTIONAL PRIMER AND METHOD OF MANUFACTURING SHOE USING THE SAME EP10744903.5 2010-08-12 EP2467440A1 2012-06-27 HUH, Sung-Hwan
The present invention provides a multifunctional primer, comprising a first solution including 15 to 55 parts by weight of natural rubber and 750 to 1350 parts by weight of an organic solvent; a second solution from 100 parts by weight of the first solution and additionally 45 to 90 parts by weight of a polyurethane-dispersion; comprising a third solution from 100 parts by weight of the second solution and 100 to 250 parts by weight of a butadiene-based rubber solution containing 50 to 200 parts by weight of a butadiene rubber and 800 to 950 parts by weight of an organic solvent. Additionally a method of manufacturing a shoe is disclosed in an environmentally friendly manner by application of the primer to a transfer sheet, this being dried and cut into appropriate pieces, and this film-type multifunctional primer applied on a non-vulcanized outersole of a shoe.
12 METHOD FOR INCREASING THE ADHESION BETWEEN THE FIRST SURFACE OF A FIRST WEB-TYPE MATERIAL AND A FIRST SURFACE OF A SECOND WEB-TYPE MATERIAL US15508607 2015-09-01 US20170283657A1 2017-10-05 Marcel HÄHNEL
A method for increasing the adhesion between the first surface of a first web-type material and a first surface of a second web-type material, the first web-type material and the second web-type material being supplied to a lamination nip continuously and with the same direction of the web. In said nip, the first surface of the first web-type material and of the second web-type material are laminated together and both first surfaces are treated with a plasma over the whole surface. The lamination nip is formed by a pressure roller and a counter-pressure roller and at least one of the surfaces of the rollers or both are equipped with a dielectric. The first web-type material comprises an adhesive compound layer arranged in the first web-type material such as to form the first surface of the first web-type material.
13 Polyurethane Adhesive Comprising Epoxide Groups US15261012 2016-09-09 US20160376474A1 2016-12-29 Holger Eichelmann; Marcel Blodau; Andre te Poel
The present invention relates to a polyurethane adhesive, in particular for laminating films, wherein the PU adhesive contains 0.1 to 20 wt % a low molecular weight epoxide comprising at least one epoxide group and at least one hydroxy group, and wherein the epoxide is chemically unbonded or is chemically bonded by means of at least one hydroxy group. The present invention further relates to use of said adhesive for adhesively bonding films, to a method for producing multilayer films, and to multilayer films adhesively bonded with said adhesive.
14 FLUID ACTIVATABLE ADHESIVES FOR GLUE-FREE, LINER-FREE LABELS FOR GLASS AND PLASTIC SUBSTRATES AND METHODS OF USE THEREOF US14792291 2015-07-06 US20150310773A1 2015-10-29 Daniel Cho; Heidi Munnelly; Benjamin Lux
Methods for applying a liner-free, or liner-less label, to a substrate, particularly glass or plastic (e.g., PET) substrates are described herein. The method includes applying an adhesive composition, such as a polymeric coating, to a label face sheet, activating the adhesive composition with an activating fluid, and contacting the label to the substrate. The activating fluid is preferably a mixture of water and one or more organic solvents, such as low molecular weight alcohols. In some embodiments, the labels exhibit a percent fiber tear greater than about 50, 55, 60, 65, 70, 75, 80, 85, 90, or 95% after one, two, three, four, or five minutes. In particular embodiments, the labels exhibits a percent fiber tear greater than 60, 65, 70, 75, 80, 85, 90, or 95% after two minutes.
15 Extendable Self-Supporting Material Composites and Manufacture Thereof US13731944 2012-12-31 US20130196120A1 2013-08-01 David A. Gray; Robert M. Hume; David A. Safranski
Specific composite materials described herein are based on the discovery that certain selections of materials and manufacturing conditions and processes provide unexpectedly improved self-supporting thin-film composite materials. It has been discovered that certain combinations of backing materials, shrink film materials, and manufacturing conditions provide improved composites having highly controllable, readily repeatable, and stable arc shaped cross-web curled structures. In general, the composite materials described herein comprise a dimensionally alterable film such as a polyester shrink film having a first surface and a second surface, and a polyester backing material having a first surface and a second surface, wherein the second surface of the backing material is laminated to the first surface of the dimensionally alterable film. Upon activation of the alterable film, for example upon exposing the composite material comprising the polyester heat shrink film to heat, the composite material can be imparted with an arc shaped cross-web curled structure along it longitudinal width, resulting in resistance to bending in its axial length, and a self-supporting material.
16 CHEMICAL COMPOSITION AND METHOD OF APPLYING SAME TO ENHANCE THE ADHESIVE BONDING OF GLASS LAMINATES US12866722 2007-12-21 US20110217558A1 2011-09-08 Paul H. Brogan; Jay M. Wendell, JR.
A chemical composition and method of applying same between glass and attached layer(s) of polyester or other plastic safety/security films to enhance the bonding of the applied adhesive therebetween as well as the strength of the glass laminate construction. In a preferred embodiment, the chemical composition is an acrylic-based mixture, containing alcohol, glycol, a slip agent, and a wetting agent. In an alternative preferred embodiment, the chemical composition is a silane-based mixture, containing alcohol, glycol, and a slip agent. The preferred embodiments of the invention are used in combination with currently available glass laminate systems to enhance the bonding and adhesion thereof.
17 Composition for the cold preparation of composite materials for adhesive bonding US11406299 2006-04-19 US07771827B2 2010-08-10 Stephane Fouquay; Jean-Pierre Lallier; Michel Miskovic
The present invention relates to a liquid composition for the cold preparation of laminate composite materials so as to confer to them, without preliminary sanding or abrasion, a surface state favorable to adhesive bonding with polyurethane type adhesives comprising (a) at least one polar aprotic solvent (TPA); (b) at least one ether (TE) selected from ethers, ether-esters, and ether-ketones having: a molar volume less than 200 cm3/mole and preferably less than 160 cm3/mole, a molecule devoid of a hydroxyl function, and (c) at least one activator (TA) comprising at least one reactive nitrogenous function of the —NH2 and/or —NH— type of molar volume less than 100 cm3/mole.
18 Thrombin-Free Biological Adhesive and Use Thereof as a Medicament US12096883 2006-12-15 US20080311190A1 2008-12-18 Abdessatar Chtourou
The invention relates to a thrombin-free, fibrinogen-based biological adhesive for therapeutic use, which comprises factor VIIa and a source of calcium ions. The invention also relates to the use of the biological adhesive as a medicament, in particular as a dressing for biological tissues, wounds or biomaterials.
19 Method of bonding non-polar or highly crystalline resin substrates employing a primer and a cyanoacrylate adhesive US78403 1987-07-27 US4818325A 1989-04-04 Akihiko Hiraiwa; Kenji Ito; Kaoru Kimura
A primer comprising an organometallic compound and an organic polymer, which is useful in bonding non-polar or highly crystalline resin substrates together or bonding said resin substrates and another material, such as a solid material, a coating material, paint or printing ink by using a 2-cyanoacrylate.
20 Compositions and methods for improving adhesion to plastic substrates US340912 1982-01-20 US4397707A 1983-08-09 Terrance H. Dawdy
Adhesion between an adhesive of the class of polymerizable liquid ethylenically unsaturated compounds containing a single vinyl group and solid polyester-containing plastic materials is improved by treating the substrate with a primer composition comprising an aromatic polyisocyanate and an amino resin and moisture-curing the polyisocyanate compound prior to application of the adhesive. The adhesive-joined assemblies are cured in a first stage at room temperature and, in a second stage, are post-baked at 100.degree. to 150.degree. C. to complete cure of the adhesive and the primer.
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