序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
41 Reverse thermal gels and uses therefor US13581518 2011-03-04 US09132199B2 2015-09-15 Thomas R. Friberg; Daewon Park; Yadong Wang
Biodegradable triblock copolymer compositions are provided which are useful in tissue engineering and drug delivery. The copolymers are reverse thermal gels in that when heated from a lower temperature to a higher temperature, they gel. These gels are useful in drug delivery when complexed with an active agent. For example the compositions can be used for intraocular injection of active agents, such as anti-angiogenic agents for treatment of a maculopathy or retinitis.
42 Organically modified hybrid aerogels US13299677 2011-11-18 US08952119B2 2015-02-10 Wenting Dong; Wendell E Rhine; Decio Coutinho
Disclosed and claimed herein are hybrid aerogels which are compositions of tetraalkoxysilanes and bis-(trialkoxysilyl)imides that exhibit low thermal conductivities and high compressive strengths. Methods for their preparation are also provided.
43 GELS US14148044 2014-01-06 US20140323676A1 2014-10-30 Mansour Mehrabi; Sriram Venkataramani; Mark Bown; Ajay D. Padsalgikar; Ramasri Mudumba
The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of a soft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.
44 ANALYTE SENSOR US13812135 2011-07-26 US20130168609A1 2013-07-04 Eric Lee; Mark Micklatcher
Matrix materials, such as sol-gels and polymers derivatives to contain a redox active material can be used to form electrodes and probes suitable for use in pH meters and other analyte sensing devices.
45 SUPPORT STRUCTURES INCLUDING LOW TACK VISCOELASTOMERIC GEL MATERIAL AND METHODS US13543250 2012-07-06 US20130011621A1 2013-01-10 David Dale Russell; Kevin Fredrick Callsen
A low tack viscoelastomeric gel material formed by combining, by percent weight: about 50% to about 80% of a Polyol; about 3% to about 15% of an isocyanate; about 15% to about 40% of an oil; about 0.1% to about 1% of a catalyst; and about 0% to about 1% of a release agent. Support structures are also provided with a layer of low tack viscoelastomeric gel material. Further aspects also include methods of making the low tack viscoelastomeric gel material and methods of making support structures with a layer of low tack viscoelastomeric gel material.
46 PROCESS FOR THE PREPARATION OF FLEXIBLE POLYURETHANE AND FOAM OBTAINED THEREBY US13394511 2010-12-03 US20120238656A1 2012-09-20 Jean-Pierre De Kesel
The present invention is directed to a process for the preparation of a flexible polyurethane foam and to the polyurethane foam prepared by that process. The foam is in particular a flexible polyurethane foam which has a density of between 25 and 120 kg/m3, a resilience, measured at 20° C. in accordance with ASTM D 3574 H, higher than 35%, and an ILD 40% hardness, measured in accordance with ISO 2439 B, of between 60 and 500 N. It is prepared by allowing a reaction mixture, which comprises a blowing agent, to foam. In order to influence the physical and/or thermophysiological properties of the foam, in particular the pressure distribution properties, at least one organogel material is dispersed in the reaction mixture before allowing it to foam.
47 Gel masses based on polyurethane, their production and use US11517237 2006-09-07 US08232364B2 2012-07-31 Andreas Hoffman; Heinz-Dieter Ebert; Matteo Mason
The present invention relates to improved gel masses prepared from a reaction mixture of NCO prepolymers and selected compounds containing groups reactive towards isocyanate groups. This invention is also directed to a process for the production of these gel masses and to the production of pressure-distributing elements comprising these gel masses.
48 Gels US12226508 2007-04-19 US20100029802A1 2010-02-04 Mansour Mehrabi; Sriram Venkataramani; Mark Bown; Ajay Padsalgikar
The present invention relates to biostable gel comprising: (a) at least one silicon-containing polyol, polyamine, polyepoxy or polyisocyanate having 1 or more functional groups and a molecular weight of at least 20,000 which is cured in the presence of: (b) at least one diol, diamine or diisocyanate having a molecular weight of less than 10,000; and/or (c) an initiator, processes for their preparation and their use in the manufacture and repair of biomaterials and medical devices, articles or implants, in particular the manufacture of asoft tissue implant such as breast implants and the repair of orthopaedic joints such as spinal discs.
49 Solid, non-expanded, filled elastomeric molded parts and a process for the preparation thereof US11895926 2007-08-28 US20080071006A1 2008-03-20 Eva Emmrich; Klaus Brecht; Uwe Pfeuffer
The invention provides solid, non-expanded, filled, molded parts which comprise an elastomeric polyurethane. This invention is also directed to a process for the production of these molded parts to the use thereof.
50 Gel masses based on polyurethane, their production and use US11517237 2006-09-07 US20070066788A1 2007-03-22 Andreas Hoffmann; Heinz-Dieter Ebert
The present invention relates to improved gel masses prepared from a reaction mixture of NCO prepolymers and selected compounds containing groups reactive towards isocyanate groups. This invention is also directed to a process for the production of these gel masses and to the production of pressure-distributing elements comprising these gel masses.
51 Emulsifier-free microgel US10536964 2003-10-13 US20060128859A1 2006-06-15 Horst Muller
Emulgator-free microgel dispersion and its use.
52 Composition for producing golf balls and multi-piece golf balls US10963518 2004-10-14 US20050277488A1 2005-12-15 Kenji Onoda; Masao Ogawa; Yuri Naka; Norikazu Ninomiya
This invention is directed to A composition for forming a golf ball, the composition comprising polyurethane gel composite particles and at least one base material selected from the group consisting of synthetic resins and elastomers, the polyurethane gel composite particles consisting of colloidal polyurea particles precipitated from a non-aqueous solvent solution of colloidal polyurea and polyurethane gel particles covered with the polyurea particles, the polyurethane gel particles being three-dimensionally crosslinked and each of the polyurethane gel particles being formed of a polyisocyanate compound and a polyethylene oxide group-free, active-hydrogen-containing compound, at least one of the compounds being trifunctional or higher valency, and is also directed to a multi-piece golf ball having one or more layers formed of this composition.
53 Process for the production of molded particles for enzyme- or microbial cell-immobilization US10293500 2002-11-14 US06855746B2 2005-02-15 Junya Yoshitake; Kenji Miyagawa; Kenji Seko
This invention provides a process for the production of molded particles for enzyme- or microbial cell-immobilization which is characterized in that:an aqueous liquid composition which comprises: (A) an unsaturated group-containing urethane resin which is obtained by making a compound (a) having one hydroxyl group and one epoxy group in a molecule react with a compound (b) having one carboxyl group and one ethylenically unsaturated group in a molecule, and further making thus obtained unsaturated group-containing diol (c) react with polyisocyanate compound (d); (B) a polymerization initiator; and (C) water-soluble macromolecular polysaccharides which are capable of gelation by contact with metal ion; is gelatinized, in an aqueous medium which contains metal ion, to be particulate gel, which is then subjected to photopolymerization and/or thermopolymerization by which to cause the crosslinking reaction of ethylenically unsaturated group in said particulate gel.
54 Gel compositions based on reaction products of polyols and polyisocyanates US09775498 2001-02-05 US06809143B2 2004-10-26 Rüdiger Nowak; Helmut Steinbach; Adolf Stender
Gel compositions based on reaction products of polyols and polyisocyanates contain as filler at least one pyrogenically produced oxide of a metal or metalloid. The gel compositions are used in structural parts or articles.
55 Polyurethane elastomer gels US10715647 2003-11-18 US20040147707A1 2004-07-29 Christopher A Arendoski
Polyurethane gels, a reaction system for preparing the gels, and a process for producing polyurethane gels. The reaction system comprises a polyisocyanate composition and an isocyanate-reactive composition comprising a relatively high molecular weight mono-ol and a relatively low molecular weight polyol having a nominal isocyanate-reactive functionality of at least 3. The gels do not require the use of plasticizers. The reaction system and process offer a surprising combination of long working time and rapid cure.
56 Polyether polyurethane polymers, gels, solutions and uses thereof US039694 1998-03-16 US5932200A 1999-08-03 Murray H. Reich; Ken Nelson; Jirina Kuzma
An improved polyurethane is prepared by reacting a diol component and an organic diisocyanate with critical selection of the amount of water in the reaction mixture and the diol component. The diol component is a long chain polyoxyethylene glycol optionally mixed with a low molecular weight polyoxyethylene glycol. A tough gel can be formed by mixing the polyurethane in a diol or triol and water solution. The tough gel can be used in burn and wound dressings, electroconductive pads, high slip materials and surgical implants. An optically clear gel can also be formed. Solutions and emulsions can be formed of the polymer and can be combined with fillers to form face creams and antiperspirants. A film can cover one side of the gel for burn and wound applications. The gel can be used in squeeze tubes and in spray cans in burn wound care dressings and industrial applications and in bags and containers for use in plastic surgery implants.
57 Organo-polysiloxane derivartives US737253 1996-10-29 US5844053A 1998-12-01 Hirofumi Nishida
The disclosed organo-polysiloxane derivative is useful as a dispersing agent for homogeneously dispersing a silicone gel in a curable resin such as an epoxy resin. The organo-polysiloxane derivative is prepared by first reacting an organo-polysiloxane compound A having an active hydrogen-containing group in each of its both terminals and having from 5 to 70 siloxane bonds with a bifunctional organic compound B having two functional groups reactable with active hydrogen. The reaction mixture obtained in the first reaction is reacted with a mixture of a bifunctional organic compound C having two active hydrogens and a bifunctional organic compound D having two functional groups reactable with the active hydrogen.
58 Polyether polyurethane polymers, gels, solutions and uses thereof US696467 1996-08-14 US5728762A 1998-03-17 Murray H. Reich; Ken Nelson; Jirina Kuzma
An improved polyurethane is prepared by reacting a diol component and an organic diisocyanate with critical selection of the amount of water in the reaction mixture and the diol component. The diol component is a long chain polyoxyethylene glycol optionally mixed with a low molecular weight polyoxyethylene glycol. A tough gel can be formed by mixing the polyurethane in a diol or triol and water solution. The tough gel can be used in burn and wound dressings, electroconductive pads, high slip materials and surgical implants. An optically clear gel can also be formed. Solutions and emulsions can be formed of the polymer and can be combined with fillers to form face creams and antiperspirants. A film can cover one side of the gel for burn and wound applications. The gel can be used in squeeze tubes and in spray cans in burn wound care dressings and industrial applications and in bags and containers for use in plastic surgery implants.
59 Polyether polyurethane polymers and gels having improved absorption and slip properties US340606 1994-11-16 US5563233A 1996-10-08 Murray H. Reich; Ken Nelson; Jirina Kuzma
An improved polyurethane is prepared by reacting a diol component and an organic diisocyanate with critical selection of the amount of water in the reaction mixture and the diol component. The diol component is a long chain polyoxyethylene glycol optionally mixed with a low molecular weight polyoxyethylene glycol. A tough gel can be formed by mixing the polyurethane in a diol or triol and water solution. The tough gel can be used in burn and wound dressings, electroconductive pads, high slip materials and surgical implants. An optically clear gel can also be formed. Solutions and emulsions can be formed of the polymer and can be combined with fillers to form face creams and antiperspirants. A film can cover one side of the gel for burn and wound applications. The gel can be used in squeeze tubes and in spray cans in burn wound care dressings and industrial applications and in bags and containers for use in plastic surgery implants.
60 Hydrophilic polyurethaneurea foams containing no toxic leachable additives and method to produce such foams US809363 1991-12-18 US5296518A 1994-03-22 Timothy G. Grasel; Clifford A. Ferrin; James L. Guthrie; Clifton L. Kehr
Hydrophilic polyurethane urea foams which are made without toxic, leachable additives are disclosed. High molecular weight, isocyanate-terminated, ethylene oxide-rich prepolymers are used in place of surfactants to make the foams.
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