| Document | Document Title |
|---|---|
| US08592685B2 |
Wiring harness installation structure for vehicle
A wiring harness installation structure is provided which can reduce the installing cost of a wiring harness by omitting an operation of injecting a water stop agent into an interior of a grommet. A grommet 21 which is fittingly mounted in a harness through hole in a body panel 7 which separates an interior from an exterior of a vehicle compartment 1 is such that an extension tubular portion 25 of a required length which is fittingly connected to a protector 13 which lies adjacent to the grommet 21 is provided at a vehicle compartment exterior area side end portion 23a of a panel fitting tubular portion 23 through a center of which a wiring harness W is inserted, whereby an exposure of the wiring harness W in proximity to the grommet 21 is prevented by the extension tubular portion 25. |
| US08592683B2 |
Insulated electric wire and wiring harness
An insulated electric wire having an external diameter of less than 1.1 mm includes a conductor and an insulator that covers the conductor, and the insulator has a thickness of 0.25 mm or less, and is made from a material that is free from a halogen element and has a breaking elongation of 10% or more and a flexural modulus of more than 2.0 GPa. |
| US08592674B2 |
Propylene based resin composition and use thereof
Means for Solving the ProblemsThe thermoplastic resin composition (X1) of the present invention comprises (A1), (B1), (C1), and optionally (D1) below: 1 to 90 wt % of an isotactic polypropylene (A1); 9 to 98 wt % of a propylene/ethylene/α-olefin copolymer (B1) containing 45 to 89 mol % of propylene-derived structural units, 10 to 25 mol % of ethylene-derived structural units, and optionally, 0 to 30 mol % of C4-C20 α-olefin-derived structural units (a1); 1 to 80 wt % of a styrene-based elastomer (C1); and 0 to 70 wt % of an ethylene/α-olefin copolymer (D1) whose density is in the range of 0.850 to 0.910 g/cm3, wherein (A1)+(B1)+(C1)+(D1)=100 wt %. |
| US08592671B2 |
Data center and auxiliary power supply unit thereof
An auxiliary power supply unit of a data center includes a thermoelectric chip module and a direct current/alternating current (DC/AC) voltage converter connected to the thermoelectric chip module. The thermoelectric chip module includes a number of thermoelectric chips. At least one sidewall of each thermoelectric chip contacts a hot pipe of the data center. The thermoelectric chips generate a direct current (DC) voltage when a temperature difference between the sidewalls of each thermoelectric chip exists. The DC/AC voltage converter converts the DC voltage into an alternating current (DC) voltage to power an air treatment device of the data center. |
| US08592669B2 |
Musical performance-related information output device, system including musical performance-related information output device, and electronic musical instrument
Provided are a musical performance-related information output device and a musical performance system capable of superimposing musical performance-related information on an audio signal without damaging the general versatility of the audio signal. The musical performance-related information output device includes a musical performance-related information acquiring section that is adapted to acquire musical performance-related information related to a musical performance of a performer, a superimposing section that is adapted to superimpose the musical performance-related information on an analog audio signal such that a modulated component of the musical performance-related information is included in a band higher than the frequency component of the analog audio signal generated in accordance with the musical performance manipulation of the performer, and an output section that outputs the analog audio signal on which the superimposing section superimposes the musical performance-related information. |
| US08592664B1 |
Maize variety hybrid X18B745
A novel maize variety designated X18B745 and seed, plants and plant parts thereof, produced by crossing Pioneer Hi-Bred International, Inc. proprietary inbred maize varieties. Methods for producing a maize plant that comprises crossing hybrid maize variety X18B745 with another maize plant. Methods for producing a maize plant containing in its genetic material one or more traits introgressed into X18B745 through backcross conversion and/or transformation, and to the maize seed, plant and plant part produced thereby. This invention relates to the maize variety X18B745, the seed, the plant produced from the seed, and variants, mutants, and minor modifications of maize variety X18B745. This invention further relates to methods for producing maize varieties derived from maize variety X18B745. |
| US08592660B1 |
Soybean cultivar 13430771
A soybean cultivar designated 13430771 is disclosed. The invention relates to the seeds of soybean cultivar 13430771, to the plants of soybean cultivar 13430771, to the plant parts of soybean cultivar 13430771, and to methods for producing progeny of soybean cultivar 13430771. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 13430771. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 13430771, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 13430771 with another soybean cultivar. |
| US08592657B1 |
Soybean variety XB42C11
A novel soybean variety, designated XB42C11 is provided. Also provided are the seeds of soybean variety XB42C11, cells from soybean variety XB42C11, plants of soybean XB42C11, and plant parts of soybean variety XB42C11. Methods provided include producing a soybean plant by crossing soybean variety XB42C11 with another soybean plant, methods for introgressing a transgenic trait, a mutant trait, and/or a native trait into soybean variety XB42C11, methods for producing other soybean varieties or plant parts derived from soybean variety XB42C11, and methods of characterizing soybean variety XB42C11. Soybean seed, cells, plants, germplasm, breeding lines, varieties, and plant parts produced by these methods and/or derived from soybean variety XB42C11 are further provided. |
| US08592656B2 |
Soybean cultivar S070142
A soybean cultivar designated S070142 is disclosed. The invention relates to the seeds of soybean cultivar S070142, to the plants of soybean S070142, to plant parts of soybean cultivar S070142, and to methods for producing a soybean plant produced by crossing soybean cultivar S070142 with itself or with another soybean variety. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. This invention also relates to soybean cultivars, or breeding cultivars, and plant parts derived from soybean variety S070142, to methods for producing other soybean cultivars, lines or plant parts derived from soybean cultivar S070142, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing the cultivar S070142 with another soybean cultivar. |
| US08592655B2 |
Sun quest lettuce variety
A new lettuce variety designated Sun Quest is described. Sun Quest is an iceberg lettuce variety exhibiting stability and uniformity. |
| US08592654B2 |
Lettuce cultivar gandhi
A lettuce cultivar, designated Gandhi, is disclosed. The invention relates to the seeds of lettuce cultivar Gandhi, to the plants of lettuce cultivar Gandhi and to methods for producing a lettuce plant by crossing the cultivar Gandhi with itself or another lettuce cultivar. The invention further relates to methods for producing a lettuce plant containing in its genetic material one or more transgenes and to the transgenic lettuce plants and plant parts produced by those methods. This invention also relates to lettuce cultivars or breeding cultivars and plant parts derived from lettuce cultivar Gandhi, to methods for producing other lettuce cultivars, lines or plant parts derived from lettuce cultivar Gandhi and to the lettuce plants, varieties, and their parts derived from the use of those methods. The invention further relates to hybrid lettuce seeds, plants, and plant parts produced by crossing cultivar Gandhi with another lettuce cultivar. |
| US08592644B2 |
Transgenic animal for production of antibodies having minimal CDRS
A transgenic animal is provided. In certain embodiments, the transgenic animal comprises a genome comprising: an immunoglobulin light chain locus comprising: a) a functional immunoglobulin light chain gene comprising a transcribed variable region encoding: i. light chain CDR1, CDR2 and CDR3 regions that are composed of 2 to 5 different amino acids; and ii. a light chain framework; and, operably linked to the functional immunoglobulin light chain gene: b) a plurality of pseudogene light chain variable regions each encoding: i. light chain CDR1, CDR2 and CDR3 regions that are composed of the same 2 to 5 different amino acids as the CDRs of the functional gene; and ii. a light chain framework that is identical in amino acid sequence to the light chain framework of the transcribed variable region. |
| US08592640B2 |
Devices and methods for dressing applicators
Devices, kits and methods described herein may be for wound healing, including the treatment, amelioration, or prevention of scars and/or keloids by applying and/or maintaining a predetermined strain in an elastic skin treatment device that is then affixed to the skin surface using skin adhesives to transfer a generally planar force from the bandage to the skin surface. Applicators are used to apply and/or maintain the strains, and some of the applicators are further configured to provide at least some mechanical advantage to the user when exerting loads onto the skin treatment device. |
| US08592639B2 |
Injection and hemostasis site
A pad of elastomeric material having a softness of typically no more than about durometer 50 Shore 00. The pad may carry adhesive and/or a housing for adhering the pad to a surface, either manually, or by adhesive tape, or another strap. Such a pad exhibits hemostatic and leak prevention properties against needle puncture holes in the skin or the wall of a hollow medical device. Particularly, hemostasis may be prevented with low pressure application of the pad to the skin. The pad may be previously applied to the skin of the patient or a wall of a medical device such as tubing or a solution bag, and the needle may then penetrate both the pad and the skin or medical device wall, to make a resealable puncture with leakage reduction and hemostasis when the needle is withdrawn. |
| US08592637B2 |
Process for preparing mononitrated organic compounds
The present invention relates to a process for continuously preparing a mononitrated organic compound, especially a process for preparing mononitrobenzene. The invention relates more particularly to an improved continuous adiabatic process for preparing nitrobenzene. |
| US08592633B2 |
Reduction of carbon dioxide to carboxylic acids, glycols, and carboxylates
Methods and systems for electrochemical conversion of carbon dioxide to carboxylic acids, glycols, and carboxylates are disclosed. A method may include, but is not limited to, steps (A) to (D). Step (A) may introduce water to a first compartment of an electrochemical cell. The first compartment may include an anode. Step (B) may introduce carbon dioxide to a second compartment of the electrochemical cell. The second compartment may include a solution of an electrolyte and a cathode. Step (C) may apply an electrical potential between the anode and the cathode in the electrochemical cell sufficient to reduce the carbon dioxide to a carboxylic acid intermediate. Step (D) may contact the carboxylic acid intermediate with hydrogen to produce a reaction product. |
| US08592632B2 |
Process for preparing cyclic diamines
The present invention relates to a process for preparing a cyclic diamine, comprising the reaction of at least one cyclic alkene with a gas mixture (G) comprising dinitrogen the subsequent conversion of monoxide to give at least one cyclic ketone and then converting the at least one cyclic ketone to a cyclic diamine. The invention also relates to the use of a cyclic diamine with primary and secondary amine functions thus obtained to prepare polyamides and polyurethanes. |
| US08592630B2 |
Processes for separating components in alkyl perfluoroalkene ether production
Disclosed are processes for reacting a perfluorinated olefin with an alcohol, an alkali metal hydroxide, and water in the presence of a phase transfer catalyst to form a reaction product mixture that separates into an aqueous phase and an organic phase. Alcohol may be present in an effective amount sufficient to form a third phase comprising at least 50% of the phase transfer catalyst. The third phase can be separated from the organic phase. Also disclosed are methods for recovering and recycling the phase transfer catalyst used in the reaction. |
| US08592627B2 |
Process for producing (meth)acrylic acid and crystallization system
A process for producing (meth)acrylic acid comprising the steps of: supplying a cooling medium to a crystallizer (1) from a heat source device (4A), thereby crystallizing (meth)acrylic acid from a crude (meth)acrylic acid solution; discharging the cooling medium from the crystallizer (1) and returning the cooling medium to the heat source device (4A); supplying a heating medium to the crystallizer (1) from a heat source device (4B), thereby melting the (meth)acrylic acid; and discharging the heating medium from the crystallizer (1) and returning the heating medium to the heat source device (4B); wherein temperature of the cooling medium returned to the heat source device (4A) is maintained constant by utilizing a first buffer tank (5); and temperature of the heating medium returned to the heat source device (4B) is maintained constant by utilizing a second buffer tank (6). |
| US08592626B2 |
Metal complex and manufacturing method therefor
Disclosed is a metal complex that can be used as a gas absorption material with superior gas absorbing properties, a gas storage material with a high storage capacity, and a gas separation material with superior gas separation performance and high adsorption capacity. Disclosed is a metal complex, and a manufacturing method therefor, which consists of: a polycyclic aromatic dihydroxy monocarboxylic acid compound, in the structural formula of which hydroxyl groups are at the farthest locations from each other, which has carboxyl groups at the locations adjacent to the hydroxyl groups, and which has 10 or more circularly conjugated π electrons, such as 3,7-dihydorxy-2-naphtoic acid or 4,4′-dihydroxy-3-biphenylcaroxylic acid; at least one metal selected from chromium, molybdenum, tungsten, manganese, iron, ruthenium, cobalt, rhodium, nickel, palladium, copper, zinc, and cadmium; and an organic ligand, such as 4,4′-bipyridyl, capable of bidentate bonding with said metal. |
| US08592625B2 |
Process for resolving S-3-(aminomethyl)-5-methylhexanoic acid
The present invention relates to a process for resolving S-3-(Aminomethyl)-5-methylhexanoic acid, which adopts benzoyl-L-glutamic acid, 4-methyl benzoyl-L-glutamic acid, benzene sulfonyl-L-glutamic acid or 4-methyl benzene sulfonyl-L-glutamic acid as a resolution agent to make a first resolution to racemic 3-aminomethyl-5-methylhexanoic acid, and adopts the resolution agent same to that of the first resolution to make a second resolution to the first resolution product to obtain the second resolution product, thus the resolution salt product is obtained, and further hydrolyzed by an acid, the resolution agent is extracted to be separated, the pH is adjusted to be neutral, the product S-3-(Aminomethyl)-5-methylhexanoic acid, i.e. the pregabalin, is then precipitated by distillation, therefore the present invention has the characteristics of polluting the environment slightly, high efficiency and stability, simpleness and practicality, producing product with high purity and a low production cost, and is suitable for large-scale production. |
| US08592621B2 |
Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease
A description is given of precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease, in particular for the prevention or treatment of Type 2 diabetes.A description is also given of uses of these precursor compounds and edible compositions, preparations for nutrition or pleasure or semi-finished products and pharmaceutical preparations, containing such precursor compounds. |
| US08592619B2 |
Bifunctional molecules comprising a cycloalkyne or heterocycloalkyne group and a redox group
The invention relates to compounds comprising a cycloalkyne or heterocycloalkyne group and a redox group. Said compounds are of general formula (I) wherein Z is a cycloalkyne or heterocycloalkyne with at least 8 links, optionally substituted by a halogen atom or a linear or branched C1 to C5 alkyl, A is an organic structure having oxidation-reduction properties, and B is an organic link between the cycloalkyne or heterocycloalkyne cycle and the organic structure A. The invention is especially applicable to the field of molecular electronics. |
| US08592617B2 |
Redox mediators
The present application is generally directed to ruthenium or osmium containing complexes and their use as redox mediators in electrochemical biosensors. |
| US08592615B2 |
Catalysts, processes for making catalysts, processes for making polyolefin compositions, and polyolefin compositions
The present invention relates to compositions and processes of making catalysts and polyolefins. More particularly, the invention relates to snap shut catalysts, processes for making the catalysts, processes for making polyolefins using the catalysts and the polyolefins resulting therefrom. |
| US08592614B2 |
Mixtures of organic emissive semiconductors and matrix materials, their use and electronic components comprising said materials
The present invention relates to new types of material mixtures composed of at least two substances, one serving as a matrix material and the other being an emission material capable of emission and containing at least one element of atomic number greater than 20, and for their use in organic electronic components such as electroluminescent elements and displays. |
| US08592610B2 |
Spiroheterocyclic tetronic acid derivatives
The present invention relates to novel compounds of the formula (I), in which W, X, Y, Z, G, A and t have the meanings given above, to a plurality of processes and intermediates for their preparation and to their use as pesticides and/or herbicides. Moreover, the invention relates to selective herbicidal compositions comprising, firstly, the spiroheterocyclic tetronic acid derivates and, secondly, a crop plant compatibility-improving compound.The present invention furthermore relates to increasing the activity of crop protection compositions comprising in particular phenyl-substituted bicyclooctane-1,3-dione derivates by adding ammonium salts or phosphonium salts and, if appropriate, penetrants, to the corresponding compositions, to processes for their preparation and to their use in crop protection as insecticides and/or acaricides and/or for preventing unwanted plant growth. |
| US08592601B2 |
Precursor phase and use thereof for preparing the magnesium tetrahydrate salt of an omeprazole enantiomer
A precursor phase of the magnesium tetrahydrate salt of an omeprazole enantiomer, and also processes for preparing it and its use for the preparation of the magnesium tetrahydrate salt are described. Crystals of the magnesium tetrahydrate salt thus obtained, and their uses, especially in the synthesis of the dihydrate form A of the magnesium salt of the enantiomer or as medicament are also disclosed. |
| US08592592B2 |
Sweet flavor modifier
The present invention includes compounds having structural formula (I), or pharmaceutically acceptable salts, solvate, and/or ester thereof. These compounds are useful as sweet flavor modifiers. The present invention also includes compositions comprising the present compounds and methods of enhancing the sweet taste of ingestible compositions. Furthermore, the present invention provides methods for preparing the compounds. |
| US08592585B2 |
Phosphorescent iridium complex with non-conjugated cyclometalated ligands, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof
The present invention discloses a phosphorescent tris-chelated transition metal complex comprising i) two identical non-conjugated cyclometalated ligands being incorporated into a coordination sphere thereof with a transition metal, and one ligated chromophore being incorporated into the coordination sphere; or ii) one non-conjugated cyclometalated ligand forming a coordination sphere thereof with a transition metal, and two ligated chromophores being incorporated into the coordination sphere, wherein the metal is iridium, platinum, osmium or ruthenium, and the ligated chromophore possesses a relatively lower energy gap in comparison with that of the non-conjugated cyclometalated ligand, the latter afforded an effective barrier for inhibiting the ligand-to-ligand charge transfer process, so that a subsequent radiative decay from an excited state of these transition complexes will be confined to the single ligated chromophore. The architecture and energy gap of the ligated chromophore are suitable for generation of high efficiency blue, green and even red emissions. |
| US08592583B2 |
Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides
The invention relates to a process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides and to the useful intermediate compounds of such process. The process allows to obtain the desired products in high yields and purity. The synthesis is starting from the coupling of an acetal with a beta-ketoester; the resultant compound is acetylated and then reacted with a dialkyl acetal of N,N-dimethylformamide to give an intermediate which is cyclized to 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxylic ester; the carboxylic ester is then hydrolyzed and the resultant carboxylic acid is finally condensed with an appropriate form of ammonia to give the desired carboxamide. The compounds prepared according to the process of the invention are endowed with protein kinase inhibiting activity and, more particularly, Cdc7 or Cdc7/Cdks inhibiting activity. The compounds are useful in the treatment of a variety of cancers, cell proliferative disorders and diseases associated with protein kinases. |
| US08592581B2 |
Trisubstituted purine derivatives
The present invention relates to compounds of formula (I) wherein: R1 and R2 are each independently H, alkyl or haloalkyl; R3 and R4 are each independently H, alkyl, haloalkyl or aryl; R5 is alkyl or cycloalkyl or cycloalkyl-alkyl, each of which may be optionally substituted with one or more OH groups; R6 is selected from cyclopropylamino, cyclopropylmethylamino, cyclobutylamino, cyclobutylmethylamino and where one of X, Y and Z is N and the remainder are CR9; R7, R8 and each R9 are independently H, alkyl or haloalkyl, wherein at least one of R7, R8 and each R9 is other than H. A further aspect of the invention relates to pharmaceutical compositions comprising compounds of formula (I), and the use of said compounds in treating proliferative disorders, viral disorders, stroke, alopecia, CNS disorders, neurodegenerative disorders, or diabetes. |
| US08592578B2 |
Process for preparing 2-(aminomethylidene)-4,4-difluoro-3-oxobutyric esters
The present invention relates to a process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters, 2-(aminomethylidene)-4,4-difluoro-3-oxobutteric esters of the formula (I) in which R1, R2 and R3 independently of one another are C1-C6-alkyl, C1-C6-haloalkyl, C2-C6-alkenyl, C3-C10-cycloalkyl or benzyl or NR2R3 is a 5- to 10-membered heterocyclic radical, to a process for preparing compounds of the formula (I) wherein an appropriate 3-aminoacrylic ester is reacted with difluoroacetyl fluoride and to the use of compounds of the formula (I) in the process for preparing difluoromethyl-substituted pyrazol-4-ylcarboxylic acids and their esters. |
| US08592577B2 |
Methods for preparing pyrimidine derivatives useful as protein kinase inhibitors
A method of preparing a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the variables of Structural Formula (I) are as described in the specification and claims. Additionally, the present invention relates to compounds of Structural Formula (I), which are useful as inhibitors of protein kinase. |
| US08592576B2 |
Unsymmetrical pyrrolobenzodiazepine-dimers for treatment of proliferative diseases
Claimed are unsymmetrical Pyrrolobenzodiazepine-dimers (PBD-dimers) of formula (I), that are unsymmetrical due at least to the values that the variables R12 and R2 represent. Formula (I), wherein: R2 is of formula (II), where A is a C5-7 aryl group, X is selected from the group comprising: OH, SH, CO2H, COH, N═C═O, NHRN, wherein RN is selected from the group comprising H and C1-4 alkyl, and (OC2H4)mOCH3, where m is 1 to 3, and either: (i) Q1 is a single bond, and Q2 is selected from a single bond and —Z—(CH2)n—, where Z is selected from a single bond, O, S and NH and n is from 1 to 3; or (ii) Q1 is —CH═CH—, and Q2 is a single bond; R12 is a C5-10 aryl group, optionally substituted by one or more substituents selected from the group comprising: halo, nitro, cyano, ether, C1-7 alkyl, C3-7 heterocyclyl and bis-oxy-C1-3 alkylene. The other variables are as defined in the claims. The compounds are useful for the treatment of proliferative diseases. |
| US08592575B2 |
Process for extraction of pectin
Embodiments of the processes provided herein allow for extraction of high quality pectins from pectin-containing plant materials using oxalic acid for extraction of the pectin containing material. Generally described, the process for extracting pectin having a high degree of polymerization includes preparing an aqueous suspension of a pectin-containing plant material; adding oxalic acid and/or a water-soluble oxalate to the aqueous suspension in an amount sufficient to provide a mixture having a pH of between 3.0 and 3.6 and a total molarity of oxalate greater than a total molarity of calcium(II); heating the mixture to a temperature from about 50 to about 80° C. for a time sufficient to extract pectin from the pectin-containing plant material; and separating the extracted pectin from the mixture. The extracted pectin desirably is characterized as having a degree of esterification (DE) of at least 72 and a high degree of polymerization, the degree of polymerization being characterized by an intrinsic viscosity of greater than about 6.5 dL/g. |
| US08592572B2 |
Liposome containing shRNA molecule targeting a thymidylate synthase and use thereof
This method provides a method for delivering shRNA targeting TS in vivo. In addition, the following is provided: an antitumor agent, which comprises short hairpin RNA (shRNA) capable of inhibiting expression of thymidylate synthase by RNAi action and a PEG-modified cationic liposome, wherein the shRNA is bound to the surface of the PEG-modified cationic liposome and has an overhang comprising at least two nucleotides at the 3′ end. |
| US08592571B2 |
RNAi modulation of APOB and uses thereof
The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides. |
| US08592560B2 |
Antibodies to apical intestinal receptors and methods of treating metabolic disease
The present invention provides pharmaceutical compositions formulated for direct delivery to the GI tract of a patient comprising an antibody specific for a target apical intestinal receptor. The present invention further provides methods of treating diseases and conditions in a patient comprising administering directly to the GI tract of the patient, compositions of the present invention wherein modulation of the target apical intestinal receptor by the antibody treats the condition. |
| US08592556B2 |
Phage φmru polynucleotides and polypeptides and uses thereof
The invention encompasses phage φmru including phage induction, phage particles, and the phage genome. Also encompassed are phage polypeptides, as well as polynucleotides which encode these polypeptides, expression vectors comprising these polynucleotides, and host cells comprising these vectors. The invention further encompasses compositions and methods for detecting, targeting, permeabilising, and inhibiting microbial cells, especially methanogen cells, using the disclosed phage, polypeptides, polynucleotides, expression vectors, or host cells. |
| US08592544B2 |
Polymeric compound containing metal complex residue and element comprising same
A polymeric compound containing a residue of a metal complex represented by formula (1) [wherein M represents a metal atom selected from ruthenium, rhodium, palladium, osmium, iridium and platinum; R1, R2, R3, R4, R5, R6 and R8 independently represent a hydrogen atom, a halogen atom, an alkyl group, or the like; m represents an integer of 1 to 3; n represents an integer of 0 to 2; Z1, Z2, Z3, Z4 and Z5 independently represent a carbon atom or a nitrogen atom, provided that at least two member of Z1, Z2, Z3, Z4 and Z5 represent a nitrogen atom, and when any one member of Z1, Z2, Z3, Z4 and Z5 represents a carbon atom, a hydrogen atom bound to the carbon atom may be substituted by a substituent; a moiety represented by formula (2) represents a bidentate monoanionic ligand; and Rx and Ry are atoms bound to the metal atom M and independently represent a carbon atom, an oxygen atom or a nitrogen atom] and a bivalent group. |
| US08592536B2 |
Catalyst preparation using H2
The invention refers to a process for preparing a Group 2 metal/transition metal olefin polymerization catalyst component in particulate form having improved polymerization properties due to the use of H2 during catalyst component preparation and the use of such catalyst components in a process for polymerizing olefins. |
| US08592535B2 |
Ziegler-natta catalyst systems and polymers formed therefrom
Processes of forming catalyst systems, catalyst systems and polymers formed therefrom are described herein. The processes generally include providing a first compound including a magnesium dialkoxide, contacting the first compound with a second compound to form a solution of reaction product “A”, wherein the second compound is generally represented by the formula: Ti(OR1)4; wherein R1 is selected from C1 to C10 linear to branched alkyls, contacting the solution of reaction product “A” with a first metal halide to form a solid reaction product “B”, contacting solid reaction product “B” with a second metal halide to form reaction product “C” and contacting reaction product “C” with reducing agent to form a catalyst component. |
| US08592533B2 |
Thermosetting composition
A thermosetting composition containing an aluminosiloxane and an epoxy silicone. The thermosetting composition of the present invention is suitably used for, for example, photosemiconductor devices mounted with blue or white LED elements (backlights for liquid crystal displays, traffic lights, outdoor big displays, advertisement sign boards, and the like). |
| US08592528B2 |
Polymer, composition and film
Polyamic acid including structural units of the following Chemical Formulae 1 and 2 is provided: In Chemical Formulae 1 and 2, each substituent is as defined in the detailed description. |
| US08592525B2 |
Composition with increased stress cracking resistance
Provided is a molding composition comprising, based on the total weight of the composition, (A) 50.0% by weight to 99.5% by weight of at least one (co)polymer which is a homopolymer or copolymer of at least 80% by weight of methyl methacrylate, (B) 0.5% by weight to 50.0% by weight of at least one copolymer obtained by polymerization of a monomer, and (C) at least one low molecular weight (meth)acrylate (co)polymer having a solution viscosity in chloroform at 25° C. (ISO 1628—part 6) of less than or equal to 55 ml/g. |
| US08592523B2 |
Low gloss thermoplastic articles
A composition of matter comprising an article derived from a composition containing: a. from about 30 to 80 wt. % of a polycarbonate component, b. from about 5 to about 50 wt. % of a polyester component, wherein when polybutylene terephthalate is present in the composition, the polybutylene terephthalate is present in conjunction with at least one other polyester that is not polybutylene terephthalate; c. about 2 to about 25 wt. % of an impact modifier; and d. a gloss reducing effective amount of a multifunctional additive comprising at least one epoxy group. The invention also includes injection molding processes, thermoforming processes for making articles. |
| US08592517B2 |
Moisture-curing formulations with time-modified phases
The invention aims to allow a curable composition to have an extended working phase followed by a short time period in which said compound becomes fully cured. This is achieved by the provision of a curable composition comprising the following components: a) at least one polyether and/or at least one polyacrylic acid ester with at least one reactive silyl group as an end-group; b) at least one organotin compound; and c) at least one compound that does not contain any tin or silicon atoms and that has at least two functional groups. Said groups are selected from the following: carboxy, carbonyl or hydroxy groups, or nitrogen atoms that are part of a ring system with aromatic character. In addition, the invention relates to a method for producing such a composition, and to the use thereof as an adhesive, a sealant or as a coating material. |
| US08592512B2 |
Carbon nanotubes and organic media containing microgels
The invention relates to a composition containing at least one microgel, at least one carbon nanotube and at least one organic medium. Said organic medium can be cross-linked or non cross-linked. |
| US08592507B2 |
Water-soluble fluid for use in machining of rare earth magnet
A polymeric flocculant is added to an aqueous solution comprising an organic acid and a basic compound to form a water-soluble fluid suitable for use in machining of rare earth magnet. |
| US08592505B2 |
Hydrophosphorylation of phosphonous acid derivatives for flame retardants
Addition compounds of a) alkylphosphonous acid derivatives of the formula A-P(═O)(OX)—H (I) and b) diester-forming olefins of formula (II) Methods for the production of the addition compounds and the use thereof are also disclosed. |
| US08592504B2 |
Amorphous siliceous powder, process for production thereof, resin composition, and semiconductor encapsulation material
A semiconductor encapsulation material which exhibits a low viscosity and further improved moldability in encapsulation even when highly loaded with an inorganic filler; an amorphous siliceous powder suitable for the preparation of a resin composition useful as the encapsulation material; and a process for the production of the amorphous siliceous powder. An amorphous siliceous powder having a content of Si and Al of 99.5 mass % or above in terms of oxides, wherein the Al content in the particle size region of 15 μm to less than 70 μm is 100 to 30000 ppm in terms of oxides; the Al content in the particle size region of 3 μm to less than 15 μm is 100 to 7000 ppm in terms of oxides; and the Al content in the whole particle size region is 100 to 25000 ppm in terms of oxides. It is preferable that the (A)/(B) ratio of the Al content (A) in the particle size region of 15 μm to less than 70 μm to the Al content (B) in the particle size region of 3 μm to less than 15 μm be 1.0 to 20. |
| US08592503B2 |
Aqueous magenta inkjet ink composition containing a mixture of a self-dispersed pigment and a xanthene dye
The invention relates to an aqueous magenta inkjet ink composition for use in ink jet printers comprising a mixture of a self-dispersed magenta pigment surface modified with functional group and a xanthene dye. The magenta ink of the present invention also contains an aqueous carrier, a polymeric additive, a surfactant, and a specific cosolvent mixture selected from the group consisting of a C2-C8 terminal alkanediol, cyclic amide compound and its derivative, trihydric alcohol and mixtures thereof. Preferably, the magenta pigment is surface modified with bisphosphonate or sulfonate group, most preferably bisphosphonate group. The magenta inkjet ink demonstrates excellent stability, good chroma and maintenance characteristics and high heater reliability in permanent and semi permanent printheads. The ink also reduced post print paper curl without sacrificing print quality. |
| US08592502B2 |
Ink composition for inkjet printing
A non-aqueous ink composition for inkjet printing is provided, which comprises 0.01 to 10 wt % of at least one ionic substance (A) selected from the group consisting of quarterly ammonium salts, quarterly phosphonium salts, a combination of a fatty acid and/or an alkyl phosphate with an amine compound, and synergists, 0.1 to 20 wt % of an C12-25 alkyl(meth)acrylate copolymer (B) having 1 to 40 wt %, relative to a weight of the copolymer, of urethane moiety, 0.1 to 20 wt % of a pigment (C), and an organic solvent (D). The composition achieves excellent wiping durability and printed image density. |
| US08592496B2 |
Telechelic hybrid aerogels
Methods of forming hybrid aerogels are described. The methods include forming a hybrid aerogel from a metal oxide precursor and a branched telechelic copolymer, e.g., co-hydrolyzing and co-condensing the metal oxide precursor and the branched telechelic copolymer. Aerogels and aerogel articles, including hydrophobic aerogels and hydrophobic aerogel articles are also described. |
| US08592492B2 |
Using fossil fuels to increase biomass-based fuel benefits
In the production of fuel such as ethanol from carbonaceous feed material such as biomass, a stream comprising hydrogen and carbon monoxide is added to the raw gas stream derived from the feed material, and the resulting combined stream is converted into fuel and a gaseous byproduct such as by a Fischer-Tropsch reaction. The gaseous byproduct may be utilized in the formation of the aforementioned stream comprising hydrogen and carbon monoxide. |
| US08592491B2 |
Water-based rare earth metal compound sol, manufacturing method thereof, and method for manufacturing ceramic powder using the same
A particulate subcomponent for a barium titanate dielectric is obtained from a sol in which a rare earth metal compound is dispersed in water. The rare earth metal compound includes a carboxylic acid having at least three carbonyl groups and at least one rare earth metal which can be Sc, Y, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, and Lu so that the molar ratio (carbonyl group/rare earth metal) is in the range of 1.2 to 3. A method of making the sol and a method of using the sol to make a ceramic powder is described. |
| US08592487B2 |
Deuterated darunavir
This invention relates to novel compounds that are hydroxyethylamino sulfonamide derivatives and pharmaceutically acceptable salts thereof. More specifically, this invention relates to novel hydroxyethylamino sulfonamide derivatives that are derivatives of darunavir. This invention also provides compositions comprising one or more compounds of this invention and a carrier and the use of the disclosed compounds and compositions in methods of treating diseases and conditions that are beneficially treated by administering a human immunodeficiency virus (HIV) protease inhibitor, such as darunavir. |
| US08592485B2 |
Methods and pharmaceutical compositions for treating the animal central nervous system for psychiatric disorders
The present invention comprises methods and pharmaceutical compositions for intranasal delivery of effective amounts of DFO directly to the CNS, in particular the brain treatments that inhibit GSK3b in patients with psychiatric disorders including, but not limited to, bipolar disorder, depression, ADHD and schizophrenia. In addition a treatment composition is disclosed which comprises DFO and in certain embodiments combines DFO with one or more of the psychotropic drug types, i.e., antipsychotics, mood stabilizers and antidepressants. Moreover, a treatment for treating impairment of neural plasticity through inhibition of GSK3b is provided as well as prevention of apoptosis of cells through inhibition of GSK3b. |
| US08592484B2 |
Cosmetic composition containing calcium citrate and N-acylated aminoalcohol derivative to prevent dry skin and signs of cutaneous ageing
Cosmetic compositions comprising calcium citrate and at least one N-acylated aminoalcohol according to formula (I). Provided is a method of treating aged skin, comprising topically applying to the aged skin a composition comprising a compound of Formula (I) in an amount effective to provide an anti-ageing effect. The compound of Formula (I) is used to prevent skin and/or to help to maintain or improve moisture retention and/or to fight against the signs of skin ageing. The N-acylated aminoalcohol of formula (I) acts as a ceramidase inhibitor. The combination of at least one compound of formula (I) and calcium citrate stimulates keratinocyte differentiation. |
| US08592483B2 |
Method for treating schizophrenia
The present invention provides a novel fatty acid derivative. The present invention also provides a method for treating schizophrenia in a mammalian subject, which comprises administering to the subject in need thereof an effective amount of a fatty acid derivative. |
| US08592476B2 |
Compounds, compositions, and methods for the treatment of β-amyloid diseases and synucleinopathies
Dihydroxyaryl compounds and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of β-amyloid diseases, such as observed in Alzheimer's disease, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment. |
| US08592474B2 |
Process for the preparation or purification of olmesartan medoxomil
The present invention relates to a process for the preparation and purification of olmesartan medoxomil hydrohalide salts and optionally converting them to olmesartan medoxomil. The invention also relates to products obtainable by the process of the invention, to pharmaceutical compositions comprising the products and to their use in medicine, particularly to treat hypertension. |
| US08592471B2 |
Substituted phenylureas and phenylamides as vanilloid receptor ligands
The invention relates to substituted phenylureas and phenylamides, to processes for the preparation thereof, to pharmaceutical compositions containing these compounds and also to the use of these compounds for preparing pharmaceutical compositions. |
| US08592470B2 |
Sitaxentan derivative
A compound represented by formula (1-1) or (1-2), or a pharmacologically acceptable salt thereof retains the principal therapeutic effect of sitaxentan and has an improved CYP inhibitory effect: wherein R1 is a halogen atom, etc., R2 is a methyl group, etc., R3 is a C1-6 alkyl group, etc., and M is a group represented by: etc. |
| US08592466B2 |
Methods for treating conditions caused by higher-than-normal dopaminergic activity in basal ganglia
Treatment of humans suffering from conditions caused by higher-than-normal dopaminergic activity in basal ganglia includes administering the compound (2S)-2-{3-[3-({[(2R,4R)-4-tert-Butoxycarbonyl-2-(2-fluorophenyl)]-3-thiazolidinyl}carbonylmethyl)ureido]phenyl}propionic acid and its physiological acceptable salts. |
| US08592465B2 |
Compounds for treatment of cancer
Compounds according to formula (I) are disclosed where Q is S, N, or O; X is optional, and can be O═, S═, ═N—NH2, ═N—OH, or —OH; Y is optional and can be —N(H)—, O, or C1 to C20 hydrocarbon; and R1 and R2 are each independently substituted or unsubstituted single-, fused- or multiple-ring aryl or (hetero)cyclic ring systems. Methods of making these compounds, pharmaceutical compositions containing the compounds, and their use, particularly for treating or preventing cancer, are also disclosed. |
| US08592462B2 |
Pirfenidone treatment for patients with atypical liver function
Methods are provided for administering pirfenidone to a patient that has exhibited abnormal biomarkers of liver function in response to pirfenidone administration. The methods include administering to a patient pirfenidone at doses lower than the full target dosage for a time period, followed by administering to the patient pirfenidone at the full target dosage. The methods also include administering pirfenidone at the full target dose with no reduction and administering permanently reduced doses of pirfenidone. |
| US08592460B2 |
Amino-pyridine derivatives as S1P1 /EDG1 receptor agonists
The invention relates to novel amino-pyridine derivatives, their preparation and their use as pharmaceutically active compounds. Said compounds particularly act as immunomodulating agents. |
| US08592452B2 |
Cyclic amine compound
A compound represented by the formula (I) wherein ring A is a 5- to 8-membered ring optionally having further substituent(s) other than R6, R7 and R8, R1 is an electron-withdrawing group, R2, R3, R4 and R5 are each independently a hydrogen atom, a halogen atom, a group bonded via a carbon atom, a group bonded via a nitrogen atom, a group bonded via an oxygen atom or a group bonded via a sulfur atom, R6 is a halogen atom, a group bonded via a carbon atom, a group bonded via a nitrogen atom, a group bonded via an oxygen atom or a group bonded via a sulfur atom, R7 is a cyano group, a nitro group, an acyl group optionally having substituent(s), an optionally esterified or amidated carboxyl group or a hydrocarbon group optionally having substituent(s), or R6 and R7 optionally form, together with the carbon atom bonded thereto, a ring optionally having substituent(s), and R8 is a hydrogen atom, a halogen atom, a group bonded via a carbon atom, a group bonded via a nitrogen atom, a group bonded via an oxygen atom or a group bonded via a sulfur atom, or a salt thereof has a superior action as an androgen receptor modulator, and is useful for the prophylaxis or treatment of hypogonadism, male climacteric disorder, frailty, cachexia, osteoporosis and the like. |
| US08592450B2 |
Compositions and methods for treatment of eye disorders
The present invention provides compounds and methods for the treatment of LFA-1 mediated diseases. In particular, LFA-1 antagonists are described herein and these antagonists are used in the treatment of LFA-1 mediated diseases. One aspect of the invention provides for diagnosis of an LFA-1 mediated disease and administration of a LFA-1 antagonist, after the patient is diagnosed with a LFA-1 mediated disease. In some embodiments, the LFA-1 mediated diseases treated are dry eye disorders. Also provided herein are methods for identifying compounds which are LFA-1 antagonists. |
| US08592449B1 |
Radiolabelled phenylimidazole-based ligands
The present invention relates to radiolabelled PDE10A ligands which are useful for imaging and quantifying the PDE10A enzyme using positron emission tomography (PET). |
| US08592446B2 |
[1,10]-phenanthroline derivatives for the treatment of neurodegenerative or haematological diseases
The present invention relates to a new family of [1,10]-phenantroline derivatives of formula (I), which are useful for the treatment or profilaxis of a neurodegenerative or haematological disease or condition, their use as a medicament, especially for treating a treatment neurodegenerative or haematological disease or condition, and a pharmaceutical composition comprising the compounds. |
| US08592445B2 |
Iso-ergoline derivatives
Provided herein are novel iso-ergoline derivatives and compositions thereof. In other embodiments, provided herein are methods of treatment, prevention, or amelioration of a variety of medical disorders such as, for example, migraine using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of agonizing receptors such as, for example, the 5-HT1D and/or the 5-HT1Breceptor, without agonizing the 5-HT2B receptor using the compounds and compositions disclosed herein. In still other embodiments, provided herein are methods of antagonizing or inhibiting activity at receptors such as, for example, the adrenergic alpha2A and/or the alpha2Breceptors using the compounds and compositions disclosed herein. |
| US08592440B2 |
Crystalline form I of imatinib mesylate
Crystalline forms of imatinib mesylate (F, G, H, I and K) and their respective characterizations are disclosed. |
| US08592438B2 |
Plant disease control composition
A plant disease control composition comprising, as an active ingredient, a compound of formula (I) or a salt thereof, and one or more anilinopyrimidine compounds selected from the group consisting of 4,6-dimethyl-N-phenyl-2-pyrimidinamine, 4-methyl-N-phenyl-6-(1-propynyl)-2-pyrimidinamine and 4-cyclopropyl-6-methyl-N-phenyl-2-pyrimidinamine has an excellent plant disease control effect. |
| US08592434B2 |
Mucoadhesive buccal tablets for the treatment of orofacial herpes
The present invention relates to the treatment or prevention of mucocutaneous herpes simplex virus diseases using prolonged release mucoadhesive buccal tablets comprising an acyclic guanosine antiviral agent. These tablets are particularly suitable for the treatment or prevention of orofacial herpes. |
| US08592432B2 |
Compounds and compositions as protein kinase inhibitors
The invention provides novel pyrimidine derivatives and pharmaceutical compositions thereof, and methods for using such compounds. For example, the pyrimidine derivatives of the invention may be used to treat, ameliorate or prevent a condition which responds to inhibition of anaplastic lymphoma kinase (ALK) activity, c-ros oncogene (ROS), insulin-like growth factor (IGF-1R), and/or insulin receptor (InsR) or a combination thereof. |
| US08592424B2 |
Topical regional neuro-affective therapy
A method of treating a disease state or condition in humans via topical brainstem afferent stimulation therapy via the administration of a drug to the back of the neck of a human patient at the hairline in close proximity to and under or on the area of skin above the brain stem to provide regional neuro-affective therapy is disclosed. |
| US08592423B2 |
Inhibitors of PDE10
PDE10 inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit PDE10 are also disclosed. |
| US08592417B2 |
2-substituted-6-heterocyclic pyrimidone derivatives as tau protein kinase 1 inhibitors
A compound represented by the formula (I), an optically active isomer thereof, or a pharmaceutical acceptable salt thereof: wherein each R1 represents hydrogen atom or the like; X represents oxygen atom or the like; A represents a C3-C7 cycloalkyl group, a C6-C10 aryl group or a heterocyclic group; R6 represents a halogen atom or the like; s represents 0 or an integer of 1 to 5; Q represents a pyridine ring which may be substituted or pyrimidine ring; and R2 represents hydrogen atom or the like, which is used for preventive and/or therapeutic treatment of a disease caused by abnormal activity of tau protein kinase 1 such as a neurodegenerative diseases (e.g. Alzheimer disease). |
| US08592415B2 |
Selective kinase inhibitors
The present invention relates to methods of modulating (for example, inhibiting) activity of JAK3, comprising contacting the JAK3 with a compound of Formula I: or pharmaceutically acceptable salt thereof, wherein constituent members are provided hereinwith. The present invention further provides novel compounds and compositions as well as their methods of preparation and use of the same as JAK3 inhibitors in the treatment of JAK3-associated diseases including, for example, inflammatory and autoimmune disorders. |
| US08592410B2 |
Cyclic inhibitors of 11BETA-hydroxysteroid dehydrogenase 1
This invention relates to novel compounds of the Formula Il Ik, Im3, Im4, Im6-12, In3, In4, In6-12, lo3, lo4, lo6-12, Ip2, Ip4-7, pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of Cortisol in a cell or the inhibition of the conversion of cortisone to Cortisol in a cell. |
| US08592409B2 |
Cyclic carbazate and semicarbazide inhibitors of 11β-hydroxysteroid dehydrogenase 1
This invention relates to novel compounds of the Formula (I), (Ia), (Ic), (Ie), (If), (Ig), (Ih), (Ii), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell. |
| US08592408B2 |
Fused aminodihydrothiazine derivatives
The present invention relates to a fused aminodihydrothiazine derivative of formula (I): wherein X is hydrogen or fluorine; A is CH or N; Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or —C≡N; and pharmaceutically acceptable salts thereof; which compound has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia. |
| US08592406B2 |
Transnasal anticonvulsive pharmaceutical composition comprising poorly soluble anticonvulsant
There is provided a transnasal anticonvulsive pharmaceutical composition including a poorly soluble anticonvulsant. The anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether and fatty acid ester, wherein the fatty acid ester is selected from the group consisting of caprylocaproyl polyoxylglyceride, isopropyl palmitate, oleoyl polyoxylglyceride, sorbitan monolaurate 20, methyl laurate, ethyl laurate, and polysorbate 20. Also, the anticonvulsive pharmaceutical composition comprising a poorly soluble anticonvulsant as an active component, which is transnasally spray-administered, comprises diethylene glycol monoethyl ether, fatty acid ester, methylpyrrolidone, water and alcohol. Therefore, the transnasal anticonvulsive pharmaceutical composition may be useful to highly enhance the bioavailability of the poorly soluble anticonvulsant. Also, the transnasal anticonvulsive pharmaceutical composition may be useful to allow the poorly soluble anticonvulsant to show the improved viscosity and/or enhanced solubility in order to effectively deliver the poorly soluble anticonvulsant at a therapeutic dose. |
| US08592403B2 |
Diazepine and diazocane compounds as MC4 agonists
The present invention relates to compounds of formula (I) wherein R1, R2, R3, R4, L and n are as defined in the specification. These compounds are useful as MC4 agonists. |
| US08592401B2 |
Methods and compounds for vitamin D therapy
Methods and compositions comprising 1,25-dihydroxyvitamin D2 are disclosed. A method for lowering or maintaining lowered serum parathyroid hormone in human patients including administering to said patients an effective amount of 1,25-dihydroxyvitamin D2 to lower or maintain lowered serum parathyroid hormone levels is disclosed. Dosage forms and dosing regimens are also disclosed. |
| US08592399B2 |
S1P receptors modulators and their use thereof
The invention relates to novel compounds that have S1P receptor modulating activity. Further, the invention relates to a pharmaceutical comprising at least one compound of the invention for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression, for example, autoimmune response. A further aspect of the invention relates to the use of a pharmaceutical comprising at least one compound of the invention for the manufacture of a medicament for the treatment of diseases and/or conditions caused by or associated with inappropriate S1P receptor modulating activity or expression such as autoimmune response. |
| US08592397B2 |
Compositions and methods for combination antiviral therapy
The present invention relates to therapeutic combinations of [2-(6-amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread®) and (2R, 5S, cis)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one(emtricitabine, Emtriva™, (-)-cis FTC) and their physiologically functional derivatives. The combinations may be useful in the treatment of HIV infections, including infections with HIV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors. The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations. |
| US08592389B2 |
MicroRNA (miRNA) and downstream targets for diagnostic and therapeutic purposes
In some embodiments, the present invention concerns antisense oligonucleotides against targets of miR-21. In some embodiments, the invention is directed to a method for diagnosing fibrosis and/or fibrosis related diseases and to a method for screening a pharmaceutically active compound for the treatment of fibrosis and/or fibrosis related diseases. The present invention further relates to compositions for use in the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions modulate the activity of a miRNA for the treatment, amelioration, and/or prevention of fibrosis. In certain embodiments, the compositions inhibit the activity of miR-21 for the treatment, amelioration, and/or prevention of fibrosis. |
| US08592385B2 |
Polymer micelle complex including nucleic acid
It is an object of the present invention to provide a polyion complex used as a non-viral gene vector, which achieves sufficiently high gene expression efficiency to a target cell. The polyion complex of the present invention comprises a block copolymer formed by binding polyethylene glycol to polycation via a disulfide group and a nucleic acid. |
| US08592382B2 |
Formulations for the oral administration of therapeutic agents and related methods
The present application relates to an oral formulation of amphotericin B and other therapeutic agents, which formulation comprises one or more fatty acid glycerol esters and one or more PEG modified phospholipids or fatty acid esters. The formulation provides enhanced bioavailability and/or increased stability of the therapeutic agent at the low pH found in gastric fluid. |
| US08592379B2 |
Metastin derivative and use thereof
The present invention provides a metastin derivative represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof, or a pharmaceutical composition containing it. The metastin derivative or a salt thereof is superior in blood stability, and has a cancer metastasis suppressive action or cancer growth suppressive action. |
| US08592378B2 |
Compound WS 727713
The present invention relates to a new compound useful as a modulator of melanocortin receptors. In particular, the present invention relates to a compound WS727713, a process for production of the compound by culturing, in a culture medium, a WS727713-producing strain belonging to Pseudonocardia and recovering the compound from a culture broth, a pharmaceutical composition containing the compound, and uses of the compound. |
| US08592376B2 |
Hair care compositions
Compositions and methods are disclosed for imparting a long-wearing shine to keratin fibers, including hair. The compositions comprise an aminosilicone polymer having a viscosity from about 800 to about 1,600 mm2/s at 25° C., and a functional group equivalent weight from about 8,000 to about 14,000 g/mol. The compositions comprise an aminosilicone polymer and optionally a shine enhancer. The compositions are useful for imparting a long-wearing shine to hair. |
| US08592375B2 |
Multifunctional context-activated protides and methods of use
This invention is directed to multifunctional, context-activated protides that have two or more effectors with individually distinct biological functions and one or more corresponding activator sites that can each initiate or amplify the biological function of one or more effectors upon context-activation. The context-activated protides of the invention are useful in the diagnosis, prophylaxis, and therapy of a broad range of pathological conditions. |
| US08592371B2 |
Aminotetrahydropyrans as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved. |
| US08592361B2 |
Functional fragrance precursor
A fragrance precursor compound comprising one or more of the compounds derived from the reaction of X—OH and an aldehyde or ketone, the fragrance precursor compounds being of the formula X—O—C(R)(R*)(R**) wherein R is a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R* is H or a C6-24 alkyl group, a C6-24 aralkyl group or a C6-24 alkaryl group; R** is O—H or O—X; O—X representing a moiety derived from X—OH, and wherein X—OH is a material containing at least one hydroxyl group and having the following structure: |
| US08592358B2 |
Storage-stable, synergistic microbicidal concentrates containing an isothiazolone, an amine and an oxidizing agent
A microbicidal composition in the form of a concentrate includes a) one or more isothiazolin-3-ones, b) one or more organic amines with an alkyl group having at least 8 carbon atoms and c) one or more oxidizing agents. The concentrate is storage-stable and is used for the preservation of technical and domestic products. |
| US08592352B2 |
Cement compositions comprising particulate foamed elastomers and associated methods
Methods of subterranean cementing involving cement compositions comprising particulate foamed elastomers and associated methods are provided. In one embodiment, the cement composition comprises a hydraulic cement, a particulate foamed elastomer, and an aqueous fluid. In one embodiment, the particulate foamed elastomer may comprise polyurethane foam. |
| US08592345B2 |
Methods of inhibiting ethylene responses in plants using dicyclopropene compounds
Methods of applying dicyclopropene compounds and compositions thereof to block ethylene receptors in plants are disclosed. Methods include applying to the plant an effective ethylene response-inhibiting amount of a dicyclopropene compound or composition thereof. Dicyclopropene compounds, enantiomers, stereoisomers or salts thereof are also provided. |
| US08592337B2 |
NOx storage materials and traps resistant to thermal aging
Nitrogen oxide storage materials and methods of manufacturing nitrogen oxide storage materials are disclosed. The nitrogen oxide storage materials can be used to manufacture catalytic trap disposed in an exhaust passage of an internal combustion engine which is operated periodically between lean and stoichiometric or rich conditions, for abatement of NOx in an exhaust gas stream which is generated by the engine. In one embodiment, the nitrogen oxide storage material comprises alkaline earth material supported on ceria particles having a crystallite size of between about 10 and 20 nm and the alkaline earth oxide having a crystallite size of between about 20-40 nm. |
| US08592336B2 |
Catalysts for ring-closing metathesis
A catalyst composition is provided, which may be used for ring closing metathesis. In the composition, a catalyst is immobilized on a siliceous mesocellular foam support. A suitable catalyst for use in the composition is a Grubbs-type catalyst or a Hoveyda-Grubbs-type catalyst. |
| US08592335B2 |
Dielectric ceramic composition and laminated ceramic capacitor
A dielectric ceramic composition contains a barium titanate based composite oxide as its main constituent, and contains a first accessory constituent including at least Al and a second accessory constituent including one or more elements selected from among Fe, Co, Ni, Cu, and Zn, wherein the content of the Al is 0.02 to 6 parts by mol with respect to 100 parts by mol of the main constituent, and the content ratio of the second accessory constituent to the Al is 0.01 to 0.4 in terms of mols. Dielectric layers are formed from a sintered body of the dielectric ceramic composition. The addition of various types of accessory elements such as rare-earth elements is possible, if necessary. This invention achieves a dielectric ceramic composition which is capable of ensuring favorable DC bias characteristics while ensuring high reliability, and a laminated ceramic capacitor using the dielectric ceramic composition. |
| US08592327B2 |
Formation of SiOCl-containing layer on exposed low-k surfaces to reduce low-k damage
A method for protecting an exposed low-k surface is described. The method includes receiving a substrate having a mask layer and a low-k layer formed thereon, wherein a pattern formed in the mask layer using a lithographic process has been transferred to the low-k layer using an etching process to form a structural feature therein. Additionally, the method includes forming a SiOCl-containing layer on exposed surfaces of the mask layer and the low-k layer, and anisotropically removing the SiOCl-containing layer from a top surface of the mask layer and a bottom surface of the structural feature in the low-k layer, while retaining a remaining portion of the SiOCl-containing layer on sidewall surfaces of the structural feature. The method further includes performing an ashing process to remove the mask layer, and thereafter, selectively removing the remaining portion of the SiOCl-containing layer from the sidewall surfaces of the structural feature. |
| US08592326B2 |
Method for fabricating an inter dielectric layer in semiconductor device
In a method for fabricating an inter dielectric layer in semiconductor device, a primary liner HDP oxide layer is formed by supplying a high density plasma (HDP) deposition source to a bit line stack formed on a semiconductor substrate. A high density plasma (HDP) deposition source is supplied to the bit line stack to form a primary liner HDP oxide layer. The primary liner HDP oxide layer is etched to a predetermined depth to form a secondary liner HDP oxide layer. An interlayer dielectric layer is formed to fill the areas defined by the bit line stack where the secondary liner HDP oxide layer is located. |
| US08592322B2 |
Method of fabricating openings
A method of fabricating openings is disclosed. First, a semiconductor substrate having a salicide region thereon is provided. An etch stop layer and at least a dielectric layer are disposed on the semiconductor substrate from bottom to top. Second, the dielectric layer and the etching stop layer are patterned to form a plurality of openings in the dielectric layer and in the etching stop layer so that the openings expose the salicide region. Then, a dielectric thin film covering the dielectric layer, sidewalls of the openings and the salicide region is formed. Later, the dielectric thin film disposed on the dielectric layer and on the salicide region is removed. |
| US08592321B2 |
Method for fabricating an aperture
A method for fabricating an aperture is disclosed. The method includes the steps of: forming a hard mask containing carbon on a surface of a semiconductor substrate; and using a non-oxygen element containing gas to perform a first etching process for forming a first aperture in the hard mask. |
| US08592320B2 |
Method for forming fin-shaped semiconductor structure
A method for fabricating a fin-shaped semiconductor structure is provided, including: providing a semiconductor substrate with a semiconductor island and a dielectric layer formed thereover; forming a mask layer over the semiconductor island and the dielectric layer; forming an opening in the mask layer, exposing a top surface of the semiconductor island and portions of the dielectric layer adjacent to the semiconductor island; performing an etching process, simultaneously etching portions of the mask layer, and portions of the semiconductor island and the dielectric layer exposed by the opening; and removing the mask layer and the dielectric layer, leaving an etched semiconductor island with curved top surfaces and various thicknesses over the semiconductor substrate. |
| US08592317B2 |
Polishing solution for CMP and polishing method using the polishing solution
The polishing solution for CMP of the invention comprises abrasive grains, a first additive and water, wherein the first additive is at least 1,2-benzoisothiazole-3(2H)-one or 2-aminothiazole. The polishing method of the invention is a polishing method for a substrate having a silicon oxide film on the surface, and the polishing method comprises a step of polishing the silicon oxide film with a polishing pad while supplying the polishing solution for CMP between the silicon oxide film and the polishing pad. |
| US08592315B2 |
Chemical mechanical polishing method
In an embodiment, a chemical mechanical polishing method for a substrate having a first layer and a stepped portion. A surface of the first layer is positioned above an upper face of the stepped portion. A polishing process for selectively removing the stepped portion is performed on the first layer by using a first slurry composition that has a self-stopping characteristic so that the first layer is changed into a second layer having a substantially flat surface. A second polishing process is performed using a second slurry composition that does not have the self-stopping characteristic, until the upper face of the stepped portion is exposed. |
| US08592311B2 |
Semiconductor device and method for forming passive circuit elements with through silicon vias to backside interconnect structures
A semiconductor wafer contains a substrate having a plurality of active devices formed thereon. An analog circuit is formed on the substrate. The analog circuit can be an inductor, metal-insulator-metal capacitor, or resistor. The inductor is made with copper. A through substrate via (TSV) is formed in the substrate. A conductive material is deposited in the TSV in electrical contact with the analog circuit. An under bump metallization layer is formed on a backside of the substrate in electrical contact with the TSV. A solder material is deposited on the UBM layer. The solder material is reflowed to form a solder bump. A wire bond is formed on a top surface of the substrate. A redistribution layer is formed between the TSV and UBM. The analog circuit electrically connects through the TSV to the solder bump on the back side of the substrate. |
| US08592308B2 |
Silicided device with shallow impurity regions at interface between silicide and stressed liner
A method of forming a semiconductor device includes forming a silicide contact region of a field effect transistor (FET); forming a shallow impurity region in a top surface of the silicide contact region; and forming a stressed liner over the FET such that the shallow impurity region is located at an interface between the silicide contact region and the stressed liner, wherein the shallow impurity region comprises one or more impurities, and is configured to hinder diffusion of silicon within the silicide contact region and prevent morphological degradation of the silicide contact region. |
| US08592305B2 |
Doping aluminum in tantalum silicide
Provided are methods of providing aluminum-doped TaSix films. Doping TaSix films allows for the tuning of the work function value to make the TaSix film better suited as an N-metal for NMOS applications. One such method relates to soaking a TaSix film with an aluminum-containing compound. Another method relates to depositing a TaSix film, soaking with an aluminum-containing compound, and repeating for a thicker film. A third method relates to depositing an aluminum-doped TaSix film using tantalum, aluminum and silicon precursors. |
| US08592304B2 |
Method for filling metal
A method for filling a metal is disclosed. First, a substrate is provided. The substrate includes a metal material layer, a dielectric layer covering the metal material layer and a hard mask layer covering the dielectric layer. The hard mask layer has at least one opening to expose the underlying dielectric layer. Second, a dry etching step is performed to etch the dielectric layer through the opening to remove part of the dielectric layer to expose the metal material layer and to form a recess and leave some residues in the recess. Then a cleaning step is performed to remove the residues and to selectively remove part of the hard mask to substantially enlarge the opening. Later, a metal fills the recess through the enlarged opening. |
| US08592298B2 |
Fabrication of floating guard rings using selective regrowth
A method for fabricating edge termination structures in gallium nitride (GaN) materials includes providing a n-type GaN substrate having a first surface and a second surface, forming an n-type GaN epitaxial layer coupled to the first surface of the n-type GaN substrate, and forming a growth mask coupled to the n-type GaN epitaxial layer. The method further includes patterning the growth mask to expose at least a portion of the n-type GaN epitaxial layer, and forming at least one p-type GaN epitaxial structure coupled to the at least a portion of the n-type GaN epitaxial layer. The at least one p-type GaN epitaxial structure comprises at least one portion of an edge termination structure. The method additionally includes forming a first metal structure electrically coupled to the second surface of the n-type GaN substrate. |
| US08592297B2 |
Wafer and method of processing wafer
A wafer including a substrate, a dielectric layer over the substrate, and a conductive layer over the dielectric layer is disclosed. The substrate has a main portion. A periphery of the dielectric layer and the periphery of the main portion of the substrate are separated by a first distance. A periphery of the conductive layer and the periphery of the main portion of the substrate are separated by a second distance. The second distance ranges from about a value that is 0.5% of a diameter of the substrate less than the first distance to about a value that is 0.5% of the diameter greater than the first distance. |
| US08592296B2 |
Gate-last fabrication of quarter-gap MGHK FET
A quarter-gap p-type field effect transistor (PFET) formed by gate-last fabrication includes a gate stack formed on a silicon substrate, the gate stack including: a high-k dielectric layer located on the silicon substrate; and a gate metal layer located over the high-k dielectric layer, the gate metal layer including titanium nitride and having a thickness of about 20 angstroms; and a metal contact formed over the gate stack. A quarter-gap n-type field effect transistor (NFET) formed by gate-last fabrication includes a gate stack formed on a silicon substrate, the gate stack including: a high-k dielectric layer located on the silicon substrate; and a first gate metal layer located over the high-k dielectric layer, the first gate metal layer including titanium nitride; and a metal contact formed over the gate stack. |
| US08592295B2 |
Gate-all around semiconductor nanowire FETs on bulk semiconductor wafers
Non-planar semiconductor devices are provided that include at least one semiconductor nanowire suspended above a semiconductor oxide layer that is present on a first portion of a bulk semiconductor substrate. An end segment of the at least one semiconductor nanowire is attached to a first semiconductor pad region and another end segment of the at least one semiconductor nanowire is attached to a second semiconductor pad region. The first and second pad regions are located above and are in direct contact with a second portion of the bulk semiconductor substrate which is vertically offsets from the first portion. The structure further includes a gate surrounding a central portion of the at least one semiconductor nanowire, a source region located on a first side of the gate, and a drain region located on a second side of the gate which is opposite the first side of the gate. |
| US08592293B2 |
Schottky barrier diodes for millimeter wave SiGe BiCMOS applications
A method for forming a Schottky barrier diode on a SiGe BiCMOS wafer, including forming a structure which provides a cutoff frequency (Fc) above about 1.0 THz. In embodiments, the structure which provides a cutoff frequency (Fc) above about 1.0 THz may include an anode having an anode area which provides a cutoff frequency (FC) above about 1.0 THz, an n-epitaxial layer having a thickness which provides a cutoff frequency (FC) above about 1.0 THz, a p-type guardring at an energy and dosage which provides a cutoff frequency (FC) above about 1.0 THz, the p-type guardring having a dimension which provides a cutoff frequency (FC) above about 1.0 THz, and a well tailor with an n-type dopant which provides a cutoff frequency (FC) above about 1.0 THz. |
| US08592292B2 |
Growth of multi-layer group III-nitride buffers on large-area silicon substrates and other substrates
A method includes forming a first epitaxial layer over a semiconductor substrate and etching the first epitaxial layer to form multiple separated first epitaxial regions. The method also includes forming a second epitaxial layer over the etched first epitaxial layer. Each epitaxial layer includes at least one Group III-nitride, and the epitaxial layers collectively form a buffer. The method further includes forming a device layer over the buffer and fabricating a semiconductor device using the device layer. The second epitaxial layer could include second epitaxial regions substantially only on the first epitaxial regions. The second epitaxial layer could also cover the first epitaxial regions and the substrate, and the second epitaxial layer may or may not be etched. The device layer could be formed during the same operation used to form the second epitaxial layer. |
| US08592291B2 |
Fabrication of large-area hexagonal boron nitride thin films
A hexagonal boron nitride thin film is grown on a metal surface of a growth substrate and then annealed. The hexagonal boron nitride thin film is coated with a protective support layer and released from the metal surface. The boron nitride thin film together with the protective support layer can then be transferred to any of a variety of arbitrary substrates. |
| US08592287B2 |
Overlay alignment mark and method of detecting overlay alignment error using the mark
A method comprises providing a semiconductor substrate having a first layer and a second layer above the first layer. The first layer haw a plurality of first patterns, vias or contacts. The second layer has second patterns corresponding to the first patterns, vias or contacts. The second patterns have a plurality of in-plane offsets relative to the corresponding first patterns, vias or contacts. A scanning electron microscope is used to measure line edge roughness (LER) values of the second patterns. An overlay error is calculated between the first and second layers based on the measured LER values. |
| US08592285B2 |
Method of bonding semiconductor substrate and MEMS device
A method of bonding a semiconductor substrate has a step of pressurizing and heating to bond a substrate 11 with a substrate 12 by eutectic bonding in a state that an aluminum containing layer 31 and a germanium layer 32 between a bonding section 30a of the substrate 11 and a bonding section 30b of the substrate 21 are overlaid and an outer end 32a of the germanium layer 32 is receded inward with respect to an outer end 31a of the aluminum containing layer 31. |
| US08592280B2 |
Fin field effect transistor devices with self-aligned source and drain regions
Improved fin field effect transistor (FinFET) devices and methods for the fabrication thereof are provided. In one aspect, a method for fabricating a field effect transistor device comprises the following steps. A substrate is provided having a silicon layer thereon. A fin lithography hardmask is patterned on the silicon layer. A dummy gate structure is placed over a central portion of the fin lithography hardmask. A filler layer is deposited around the dummy gate structure. The dummy gate structure is removed to reveal a trench in the filler layer, centered over the central portion of the fin lithography hardmask, that distinguishes a fin region of the device from source and drain regions of the device. The fin lithography hardmask in the fin region is used to etch a plurality of fins in the silicon layer. The trench is filled with a gate material to form a gate stack over the fins. The filler layer is removed to reveal the source and drain regions of the device, wherein the source and drain regions are intact and self-aligned with the gate stack. |
| US08592279B2 |
Electronic device including a tapered trench and a conductive structure therein and a process of forming the same
An electronic device can include a semiconductor layer, and a trench extending into the semiconductor layer and having a tapered shape. In an embodiment, the trench includes a wider portion and a narrower portion. The electronic device can include a doped semiconductor region that extends to a narrower portion of the trench and has a dopant concentration greater than a dopant concentration of the semiconductor layer. In another embodiment, the electronic device can include a conductive structure within a relatively narrower portion of the trench, and a conductive electrode within a relatively wider portion of the trench. In another embodiment, a process of forming the electronic device can include forming a sacrificial plug and may allow insulating layers of different thicknesses to be formed within the trench. |
| US08592277B2 |
Method of forming low resistance gate for power MOSFET applications
A method for forming a trench gate field effect transistor includes forming, in a semiconductor region, a trench followed by forming a dielectric layer lining a sidewall and a bottom surface of the trench. The method also includes, forming a first polysilicon layer on the bottom surface of the trench. The method further includes, forming a conductive material layer on an exposed surface of the first polysilicon layer and forming a second polysilicon layer on an exposed surface of the conductive material layer. The method still further includes, performing rapid thermal processing to cause the first polysilicon layer, the second polysilicon layer and the conductive material layer to react. |
| US08592276B2 |
Fabrication method of vertical silicon nanowire field effect transistor
The present invention discloses a fabrication method of a vertical silicon nanowire field effect transistor having a low parasitic resistance, which relates to a field of an ultra-large-integrated-circuit fabrication technology. As compared with a conventional planar field effect transistor, on one hand the vertical silicon nanowire field effect transistor fabricated by the present invention can provide a good ability for suppressing a short channel effect due to the excellent gate control ability caused by the one-dimensional structure, and reduce a leakage current and a drain-induced barrier lowering (DIBL). On the other hand, an area of the transistor is further reduced and an integration degree of an IC system is increased. |
| US08592274B2 |
LDMOS with accumulation enhancement implant
A lateral double-diffused metal-oxide-semiconductor (LDMOS) transistor device includes an enhancement implant region formed in a portion of an accumulation region proximate a P-N junction between body and drift drain regions. The enhancement implant region contains additional dopants of the same conductivity type as the drift drain region. There is a gap between the enhancement implant region and the P-N junction. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. |
| US08592273B2 |
Method of manufacturing nonvolatile memory device
In a non-volatile memory device and method of manufacturing the same, a device isolation pattern and an active region extend in a first direction on a substrate. A first dielectric pattern is formed on the active region of the substrate. Conductive stack structures are arranged on the first dielectric pattern and a recess is formed between a pair of the adjacent conductive stack structures. A protection layer is formed on a sidewall of the stack structure to protect the sidewall of the stack structure from over-etching along the first direction. The protection layer includes an etch-proof layer having oxide and arranged on a sidewall of the floating gate electrode and a sidewall of the control gate line and a spacer layer covering the sidewall of the conductive stack structures. |
| US08592272B2 |
Method of manufacturing non-volatile semiconductor memory device
A method of manufacturing a non-volatile semiconductor memory device of an embodiment includes: forming, on a semiconductor substrate, an element isolation region to be filled with a first insulating film; forming memory cell gate electrodes on element regions; etching the first insulating film so that the first insulating film remains in the element isolation region of a region in which a select gate electrode is to be formed; forming a second insulating film on the memory cell gate electrodes so that an air gap is created between the memory cell gate electrodes; forming two select gate electrodes; forming carbon side walls on the select gate electrodes; implanting ions of an impurity between the two select gate electrodes with the side walls as a mask; and removing the carbon side walls. |
| US08592267B2 |
Semiconductor device and manufacturing method of the same
At least part of a semiconductor layer or a semiconductor substrate includes a semiconductor region having a large energy gap. The semiconductor region having a large energy gap is preferably formed from silicon carbide and is provided in a position at least overlapping with a gate electrode provided with an insulating layer between the semiconductor region and the gate electrode. By making a structure in which the semiconductor region is included in a channel formation region, a dielectric breakdown voltage is improved. |
| US08592265B2 |
Method for manufacturing semiconductor device having a metal gate electrode
Example embodiments relate to a method for manufacturing a semiconductor device, wherein a metal gate electrode therein may be formed without a void in a lower portion of the metal gate electrode. The method may include providing a substrate, forming a dummy gate electrode on the substrate, forming a gate spacer on the substrate to be contiguous to the dummy gate electrode, forming a first recess by simultaneously removing a portion of the dummy gate electrode and a portion of the gate spacer, the first recess having an upper end wider than a lower end, forming a second recess by removing the dummy gate electrode remaining after forming the first recess, and forming a metal gate electrode by depositing a metal to fill the first and second recesses. |
| US08592256B2 |
Circuit board manufacturing method, semiconductor manufacturing apparatus, circuit board and semiconductor device
There is provided a circuit board manufacturing method that makes it possible to manufacture a next-generation semiconductor device in a stable manner and improve the yield during secondary mounting processing. A circuit board 11 with a thickness of 230 μm manufactured using a cyanate-based prepreg 12 containing a resin composition with which a glass cloth is impregnated is heated at a higher temperature than a glass transition temperature of the resin composition after it is cured before reflow processing. |
| US08592254B2 |
Microelectronic devices with improved heat dissipation and methods for cooling microelectronic devices
Microelectronic devices with improved heat dissipation, methods of making microelectronic devices, and methods of cooling microelectronic devices are disclosed herein. In one embodiment, the microelectronic device includes a microelectronic substrate having a first surface, a second surface facing opposite from the first surface, and a plurality of active devices at least proximate to the first surface. The second surface has a plurality of heat transfer surface features that increase the surface area of the second surface. In another embodiment, an enclosure having a heat sink and a single or multi-phase thermal conductor can be positioned adjacent to the second surface to transfer heat from the active devices. |
| US08592253B2 |
Hybrid layers for use in coatings on electronic devices or other articles
A method for protecting an electronic device comprising an organic device body. The method involves the use of a hybrid layer deposited by chemical vapor deposition. The hybrid layer comprises a mixture of a polymeric material and a non-polymeric material, wherein the weight ratio of polymeric to non-polymeric material is in the range of 95:5 to 5:95, and wherein the polymeric material and the non-polymeric material are created from the same source of precursor material. Also disclosed are techniques for impeding the lateral diffusion of environmental contaminants. |
| US08592252B2 |
Semiconductor device and method of forming through hole vias in die extension region around periphery of die
A semiconductor wafer contains a plurality of semiconductor die. The semiconductor wafer is diced to separate the semiconductor die. The semiconductor die are transferred onto a carrier. A die extension region is formed around a periphery of the semiconductor die on the carrier. The carrier is removed. A plurality of through hole vias (THV) is formed in first and second offset rows in the die extension region. A conductive material is deposited in the THVs. A first RDL is formed between contact pads on the semiconductor die and the THVs. A second RDL is formed on a backside of the semiconductor die in electrical contact with the THVs. An under bump metallization is formed in electrical contact with the second RDL. Solder bumps are formed on the under bump metallization. The die extension region is singulated to separate the semiconductor die. |
| US08592250B2 |
Self-aligned process to fabricate a memory cell array with a surrounding-gate access transistor
A memory array including a plurality of memory cells. Each word line is electrically coupled to a set of memory cells, a gate contact and a pair of dielectric pillars positioned parallel to the word line. Dielectric pillars are placed on both sides of the gate contact. Also a method to prevent a gate contact from electrically connecting to a source contact for a plurality of memory cells on a substrate. The method includes formation of a pair of pillars made of an insulating material over the substrate, depositing an electrically conductive gate material between and over the pillars, etching the gate material such that it both partially fills a space between the pair of pillars and forms a word line for the memory cells, and depositing a gate contact between the dielectric pillars such that the gate contact is in electrical contact with the gate material. |
| US08592248B2 |
Etching method for use with thin-film photovoltaic panel
The present invention relates to a chemical etching method to electrically isolate the edge from the interior of a thin-film photovoltaic panel comprising a substrate and a photovoltaic laminate. The method comprises a step to dispense an etching paste comprising two or more acids on the laminate periphery; an optional step to apply heat to the laminate; and a step to remove the etching paste. The method is further characterized by the chemical removal of at least two chemically distinctive layers of the laminate at the periphery where the etching paste is applied. The method may be used to produce a thin-film photovoltaic panel. |
| US08592245B2 |
Substrate bias for CMOS imagers
A CMOS image sensor is disclosed. The CMOS imager includes a lightly doped semiconductor substrate of a first conductivity type. At least one CMOS pixel of a second conductivity type is formed in the semiconductor substrate. The semiconductor substrate is configured to receive a bias voltage applied for substantially depleting the semiconductor substrate and for forming a depletion edge within the semiconductor substrate. A well of the second conductivity type substantially surrounds the at least one CMOS pixel to form a depletion region about the at least one CMOS pixel operable to form a minimum predetermined barrier to the depletion edge within the semiconductor substrate to pinch off substrate bias in proximity to the return contact. |
| US08592240B2 |
Method for manufacturing semiconductor light-emitting element
Provided is a method for manufacturing a semiconductor light-emitting element having a narrow wavelength distribution and comprising a substrate and a group III compound semiconductor layer formed thereon, the substrate being made of a material different from the compound semiconductor constituting the semiconductor layer. The method for manufacturing a semiconductor light-emitting element having a group III compound semiconductor layer is characterized by comprising a semiconductor layer-forming step wherein a group III compound semiconductor layer having a total thickness of not less than 8 μm is formed on a substrate (11) having a diameter D, a thickness and an amount of warpage H within the range of ±30 μm. The method is also characterized in that the diameter D and the thickness d of the substrate (11) satisfy the following formula (1): 0.7×102≦(D/d)≦1.5×102 (1). |
| US08592238B2 |
Array substrate for liquid crystal display device and method of fabricating the same
A method of fabricating a liquid crystal display device includes: a first step of attaching a polarizing plate to an outer surface of a liquid crystal panel; a second step of attaching a tape carrier package (TCP) to the liquid crystal panel; a third step of coating a resin onto a rear surface of the TCP and a connection portion of the liquid crystal panel and the TCP; a fourth step of inspecting the TCP and the liquid crystal display panel; a fifth step of inserting the liquid crystal panel into a transferring means; a sixth step of transferring the transferring means; a seventh step of extracting the liquid crystal panel from the transferring means; a eighth step of attaching the TCP to a printed circuit board (PCB); a ninth step of inspecting the PCB, the TCP and the liquid crystal panel; and a tenth step of assembling the liquid crystal panel and a backlight unit with a plurality of frames. |
| US08592237B2 |
Method of manufacturing a thin film transistor including forming bus line patterns in a substrate and filling with metal
A method for manufacturing a thin film transistor substrate including forming bus lines by etching a surface of a substrate to form bus line patterns and filling the bus line patterns with a bus line metal; forming a semiconductor channel layer at one portion of a pixel area defined by the bus lines; and forming source-drain electrodes on the semiconductor channel layer, a pixel electrode extending from the drain electrode within the pixel area, and a common electrode parallel with the pixel electrode. The bus lines are formed as being thicker but the bus lines are buried in the substrate so that the line resistance can be reduced and the step difference due to the thickness of bus line does not affect the device. |
| US08592235B2 |
Method for preparing phosphor and light emitting device
A method for preparing a phosphor includes: dissolving at least one metal as a raw material of a desired phosphor in liquid ammonia to form a metal-amide type precursor; gathering the metal-amide type precursor; and firing the precursor to form a desired phosphor. |
| US08592230B2 |
Method for patterning a substrate using ion assisted selective depostion
A method of patterning a substrate includes providing a focusing plate adjacent to a plasma chamber containing a plasma, the focusing plate configured to extract ions from the plasma through at least one aperture that provides focused ions towards the substrate. The method further includes directing first ions through the at least one aperture to one or more first regions of the substrate so as to condense first gaseous species provided in ambient of the substrate on the one or more first regions of the substrate. |
| US08592226B2 |
Surface-enhanced raman nanobiosensor
The present invention relates to biosensors, in particular to surface-enhanced Raman biosensors for detection of in vivo and ex vivo analytes. In particular, the present invention provides compositions and methods for the in vivo detection of analytes such as glucose. |
| US08592221B2 |
Manipulation of fluids, fluid components and reactions in microfluidic systems
Microfluidic structures and methods for manipulating fluids, fluid components, and reactions are provided. In one aspect, such structures and methods can allow production of droplets of a precise volume, which can be stored/maintained at precise regions of the device. In another aspect, microfluidic structures and methods described herein are designed for containing and positioning components in an arrangement such that the components can be manipulated and then tracked even after manipulation. For example, cells may be constrained in an arrangement in microfluidic structures described herein to facilitate tracking during their growth and/or after they multiply. |
| US08592216B2 |
Labeling peptides with tertiary amines and other basic functional groups for improved mass spectrometric analysis
The present invention provides methods for enhancing the fragmentation of peptides for mass spectrometry by modifying the peptides with a tagging reagent containing a functional group, such as a tertiary amine, having a greater gas-phase basicity than the amide backbone of the peptide. These high gas-phase basicity functional groups are attached to a peptide by reacting the tagging reagent to one or more available carboxylic acid groups of the peptide. Linking these high gas-phase functional groups to the peptides leads to higher charge state ions from electrospray ionization mass spectrometry (ESI-MS), which fragment more extensively during fragmentation techniques, particularly non-ergodic fragmentation techniques such as electron capture dissociation (ECD) and electron transfer dissociation (ETD). |
| US08592215B2 |
Microfabricated crossflow devices and methods
This invention provides microfabricated devices and methods for detecting, analyzing and sorting biological materials and particles. Droplets containing the particles are provided in an extrusion fluid, passed through a detection region, and then directed into a branch channel according to predetermined characteristics. For example, cells or viral particles contained in droplets of aqueous solvent are flowed past a detector in the nonpolar extrusion fluid decane, and routed into a selected branch channel for subsequent analysis or use. |
| US08592207B2 |
Method for producing transformed earthworms using earthworm's gonad-regeneration capability, transformed earthworms thereof, and method for producing recombinant proteins from transformed earthworm body fluids
The present invention relates to a method for producing transformed earthworms using the gonad-regenerating capability of earthworms, to transformed earthworms produced by the method, and to a method for producing recombinant proteins from the body fluids of transformed earthworms. The method for producing transformed earthworms according to the present invention is a novel biotechnology technique which overcomes the drawbacks of conventional transgenesis techniques, and which has high injection efficiency. The method for producing transformed earthworms according to the present invention uses regenerative blast cells having totipotency, such as embryonic stem cells, and therefore, recombinant genes can be incorporated throughout the entire transformant, and recombinant proteins can be made from the body fluids of the transformant. The method of the present invention injects a target gene directly into a gonad, thus eliminating the need of a surrogate (animal), and uses a fertile transformant, thus continuously producing a plurality of transformants. The method of the present invention is simpler than conventional transgenesis techniques, and does not require expensive equipment or expertise. |
| US08592206B2 |
Culture based screening assay and methods of use thereof to identify agents which modulate tumor development, invasion and differentiation
A 3D organotypic culture which phenocopies aggressive, invasive cancer and methods of use thereof are provided. |
| US08592204B2 |
Ultrasound and acoustophoresis for collection and processing of oleaginous microorganisms
Microorganisms such as microalgae are collected and separated from a host medium such as water. Cellular walls and membranes of the microorganisms are then ruptured to release their lipids using a lipid extraction unit. Thereafter, the lipids from the host medium are collected and separated using a lipid collection and separation unit. Related apparatus, systems, techniques and articles are also described. |
| US08592202B2 |
Biosensors for detecting macromolecules and other analytes
The invention generally provides molecular biosensors. In particular, the invention provides molecular biosensors having one or more aptamers. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules. |
| US08592200B2 |
Post protein hydrolysis removal of a potent ribonuclease inhibitor and the enzymatic capture of DNA
The present invention concerns compositions and methods of extracting infectious pathogens from a volume of blood. In one embodiment, the method includes the steps of creating a fibrin aggregate confining the pathogens and introducing a fibrin lysis reagent to expose the pathogens for analysis. The present invention also concerns materials and methods for removing aurintricarboxylic acid (ATA) from a sample. |
| US08592194B2 |
Glucoamylase variants with altered properties
The present invention relates to variant glucoamylases wherein the variant has altered properties (e.g., improved thermostability and/or specific activity) compared to a corresponding parent glucoamylase. The present invention also relates to enzyme compositions comprising a variant glucoamylase (e.g., starch hydrolyzing compositions); DNA constructs comprising polynucleotides encoding the variants and methods of producing the variant glucoamylases in host cells. |
| US08592192B2 |
Protein stabilization by domain insertion into a thermophilic protein
A strategy to improve protein stability by domain insertion. TEM 1 beta-lactamase (BLA) and exo-inulinase, as model target enzymes, are inserted into a hyperthermophilic maltose binding protein from Pyrococcus furiosus (PfMBP). Unlike conventional protein stabilization methods that employ mutations and recombinations, the inventive approach does not require any modification on a target protein except for its connection with a hyperthermophilic protein scaffold. For that reason, target protein substrate specificity was largely maintained, which is often modified through conventional protein stabilization methods. The insertion was achieved through gene fusion by recombinant DNA techniques. |
| US08592187B2 |
Alleles of the oxyR gene from coryneform bacteria
The invention relates to mutants and alleles of the oxyR gene of coryneform bacteria coding for variants of the OxyR transcription regulator and processes for producing amino acids using bacteria which comprise these alleles. |
| US08592184B2 |
Nucleic acid amplification in the presence of modified randomers
The present invention is directed to a composition comprising a DNA Polymerase which is preferably thermostable, Deoxynucleotides, at least one primer oligonucleotide or a pair of amplification primers, and randomized 5-8 mer oligonucleotide, characterized in that said oligonucleotide comprises a modification with an organic hydrophobic moiety Such a composition is specifically useful for performing hot start PCR. |
| US08592183B2 |
Apparatus and method for sequencing nucleic acid molecules
The sequence of a target polynucleotide can be determined by: (i) contacting the target polynucleotide with a polymerase enzyme and one of the nucleotides A, T(U), G and C under conditions suitable for the polymerase reaction to proceed; (ii) measuring the time taken for the polymerase to bind to and subsequently dissociate from the target polynucleotide, to thereby determine whether the polymerase has incorporated the nucleotide onto the target polynucleotide; (iii) optionally repeating steps (i) and (ii) with additional nucleotides, to thereby identify the sequence of the target polynucleotide. |
| US08592182B2 |
High throughput nucleic acid sequencing by spacing
Nucleic acid sequencing methods and related devices, products and kits are disclosed. Methods for sequencing a target nucleic acid comprise providing a daughter strand produced by a template-directed synthesis, the daughter strand comprising a plurality of subunits coupled in a sequence corresponding to a contiguous nucleotide sequence of all or a portion of the target nucleic acid, wherein the individual subunits comprise a probe and a reporter construct. The subunit encodes sequence information in its reporter construct that is less than sequence information in the corresponding portion of the target nucleic acid. The reduced information allows for reduced resolution requirements on the detection system and for increased size of resolvable reporter groups. |
| US08592178B2 |
Process for the preparation of testosterone
The present invention relates to an industrial process for the reduction of 4-androstene-3,17-dione in order to obtain testosterone using a particularly stable and selective enzyme produced in a recombinant manner. |
| US08592173B2 |
Cancer diagnosis by measuring polyisoprenylated methylated protein methyl esterase activity
Methods for cancer diagnosis, making decisions on appropriate cancer treatment, awareness of a predisposition to cancer and potential cancer prevention, and monitoring of cancer therapy by measuring the activity of PMPMEase. |
| US08592171B1 |
Method and assay for detection of residues
Embodiments described herein include methods and assays for detecting an analyte in a sample using a plurality of control zone capture agents. Some embodiments include detection of multiple analytes in a sample utilizing a plurality of analyte binders and a control zone containing multiple control zone capture agents. In some embodiments, the multiple control zone capture agents capture a plurality of binders within one control zone. Test results are determined by comparison of the control zone signal to a test zone signal. |
| US08592170B2 |
High molecular weight Ngal as a biomarker for chronic kidney disease
A high molecular weight form of Ngal is provided which can be used to diagnose chronic kidney disease. High molecular weight Ngal is about 75 kDa to about 350 kDa, and comprises non-Ngal proteins, such as polymeric immunoglobulin receptor, alpha-2-macroglobulin and immunoglobulin heavy chain. Methods are disclosed for assessing high molecular weight Ngal in a diagnostic sample from a subject. |
| US08592168B2 |
Methods for diagnosing and treating neuroendocrine cancer
The present invention relates to a method for diagnosing neuroendocrine cancers via detecting the presence of N-methyl D-asparate-associated (NMDA) glutamate receptors type 1 and/or type 2. Methods for preventing and treating neuroendocrine cancers are also disclosed. |
| US08592163B2 |
Method of determining immune enhancement of virus infectivity using Fc receptor-transfected cell lines
The present invention relates to a method of detecting immune enhancement of virus infectivity, a method of determining neutralization and immune enhancement of virus infectivity, a method of identifying a virus epitope that displays immune enhancement, a method of identifying a compound that modulates activity of an Fc receptor, and a method of identifying a compound that modulates intracellular signaling of an Fc receptor. DNA constructs, cells, and kits relating to these assays are also disclosed. |
| US08592161B2 |
Mutational profiles in HIV-1 protease correlated with phenotypic drug resistance
The present invention is directed to the field of nucleic acid diagnostics and the identification of base variation in target nucleic acid sequences. More particularly, the present invention relates to the use of such genotypic characterization of a target population of HIV and the subsequent association, i.e., correlation, of this information to phenotypic interpretation in order to correlate virus mutational profiles with drug resistance. The invention also relates to methods of utilizing the mutational profiles of the invention in drug development, i.e., drug discovery, drug design, drug modification, and therapy, treatment design, clinical management and diagnostic analysis. |
| US08592159B2 |
Method for detecting presumed IgA nephropathy and method for screening IgA nephropathy patients
A process for detecting presumed IgA nephropathy by detection of Treponema bacteria and/or Campylobacter bacteria present in a sample from the tonsil of a subject who, optionally, has a positive result in a urinary protein test and/or a urinary occult blood test, or whom is diagnosed with possible IgA nephropathy. Also, a process for detecting an IgA nephropathy patient for whom tonsillectomy is effective by detecting Treponema bacteria or Campylobacter bacteria. |
| US08592157B2 |
Method for separating an analyte from a sample
An analyte is separated from a fluid sample by introducing the sample into a cartridge having a sample port and a first flow path extending from the sample port. The first flow path includes an extraction chamber containing a solid support for capturing the analyte from the sample. The cartridge has a second flow path for eluting the captured analyte from the extraction chamber, the second flow diverging from the first flow path after passing through the extraction chamber. The sample is forced to flow through the extraction chamber and into a waste chamber, thereby capturing the analyte with the solid support as the sample flows through the extraction chamber. The captured analyte is then eluted from the extraction chamber by forcing an elution fluid to flow through the extraction chamber and along the second flow path. |
| US08592156B2 |
Predicting response to anti-CD20 therapy in DLBCL patients
This invention provides methods, compositions, and kits relating to biomarkers whose expression levels are correlated with diffuse large B-cell lymphoma (DLCBL) patients' response to treatment with a CD20 antagonist, such as a CD20 antibody, exemplified by rituximab. The methods, compositions, and kits of the invention can be used to identify DLBCL patients who are likely or not likely, to respond to anti-CD20 treatments. |
| US08592154B2 |
Methods and apparatus for high speed operation of a chemically-sensitive sensor array
Methods and apparatus relating to FET arrays for monitoring chemical and/or biological reactions such as nucleic acid sequencing-by-synthesis reactions. Some methods provided herein relate to improving signal (and also signal to noise ratio) from released hydrogen ions during nucleic acid sequencing reactions. |
| US08592152B2 |
Gene detection assay for improving the likelihood of an effective response to an EGFR antagonist cancer therapy
The invention provides a method for more effective treatment of patients susceptible to or diagnosed with tumors overexpressing EGFR, as determined by a gene amplification assay, with an EGFR antagonist. Such method comprises administering a cancer-treating dose of the EGFR antagonist, preferably in addition to chemotherapeutic agents, to a subject in whose tumor cells erbB1 gene has been found to be amplified e.g., by fluorescent in situ hybridization. EGFR antagonists described include an anti-EGFR antibody. |
| US08592141B2 |
Western blot by incorporating an affinity purification zone
A mixture of components is flowed through a binding channel region comprising a component-binding moiety, thereby binding at least a portion of a component of interest. The mixture is then flowed through a separation channel region that includes a buffer comprising a detergent, resulting in separated components. Diluent is mixed with the separated components, diluting the detergent, and the separated components are detected. The component of interest is released from the component-binding moiety and flowed through the separation channel region. Diluent is mixed with the released component of interest, diluting the detergent, and the released component of interest is detected. |
| US08592136B2 |
Methods for producing codes for microparticles
Methods and apparatus are provided for forming a plurality of encoded microparticles with a printing process to define a code for identifying the microparticles. In some embodiments the printing process includes printing steps performed with photolithography. |
| US08592131B2 |
Ortho-nitrobenzyl ester compound and positive type photosensitive resin composition including the same
An ortho-nitrobenzyl ester compound including a compound represented by Chemical Formula 1, and a positive photosensitive resin composition including the same are provided. |
| US08592124B2 |
Toner for development of electrostatic image, electrostatic image developer, toner cartridge, process cartridge, and image forming apparatus
A toner having: a peak temperature before fixation T1a of about 40° C. or more; and a peak temperature after fixation T1b that is lower than T1a by from about 10° C. to about 35° C.: T1a being a peak temperature of an endothermic peak occurring at the lowest temperature in a range of from 0° C. to 100° C. and obtained at a first warming-up step of a differential scanning calorimetry measurement that uses a toner before fixation as a sample; T1b being a peak temperature of an endothermic peak occurring at the lowest temperature within a range of from 0° C. to 100° C. and obtained at a first warming-up step of a differential scanning calorimetry measurement that uses a toner after fixation as a sample; and the toner after fixation being contained in a fixed image transferred from a transferring member and fixed on a recording medium, a maximum width of an image defect formed after conducting a folding test of the fixed image being 0.30 mm or less. |
| US08592120B2 |
Resin for toner and toner composition
The object is to develop a resin for a toner, which has both of hot offset resistance and a low-temperature fixing property even when used in a high-speed and energy-saving toner. Thus, disclosed is a resin for a toner, which comprises a polyester resin (A) having a THF insoluble fraction content of 1 to 36 wt %, a peak top molecular weight of 4500 to 20000 as measured by gel permeation chromatography on a THF soluble fraction, and a softening point of 120 to 180° C., and meeting the requirements represented by the following formulae (1) and (2): (Acid value)/(hydroxyl value)≧1 (acid value=15 to 80 mgKOH/g, hydroxyl value≧3.0 mgKOH/g) Formula (1) (A numeric value of the THF-insoluble fraction content expressed in % by weight)/(a numeric value of the softening point expressed in degree ° C.)≦0.2 Formula (2). |
| US08592119B2 |
Super low melt toner with core-shell toner particles
A toner particle having a core and a shell, and a method for making the toner particle. The core includes a crystalline resin and the shell includes an amorphous resin. The shell is substantially to completely free of the crystalline resin. The toner particle permits inclusion of greater amounts of crystalline resin materials in the core, thereby lowering the minimum fusing temperature of the toner formed from the particles. |
| US08592115B2 |
Toner compositions and developers containing such toners
A toner composition with a novel surface additive package for developing images. The additive package includes sol-gel silica, a PDMS silica, an organic spacer such as PMMA and two HMDS silicas. The toner composition exhibits improved control of voltage, higher print density, lower toner amount remaining on the roll, lower toner usage, and reduced drum contamination. The toner composition also exhibits improved dry rheological properties and improved fix properties. These improved properties make this toner composition useful for higher speed printing while using less toner. |
| US08592112B2 |
Orange toner and toner cartridge for storing the same, orange developer and process cartridge for storing the same, color toner set, and image forming apparatus
An orange toner including a binder resin containing a polyester resin having a dodecenyl succinic acid structure as a constituent unit; and C.I. Pigment Orange 38 in a blending amount of from 5% by mass to 18% by mass relative to the whole mass of the toner and a toner storage container for storing the same, an orange developer and a process cartridge for storing the same, a color toner set, and an image forming apparatus. |
| US08592111B2 |
LCD panel photolithography process and mask
Disclosed is an LCD panel photolithography process, employed in a lithography system for manufacturing a plurality of LCD panel, comprising steps of: performing photolithography to a glass substrate with a first mask, and the first mask comprises a plurality of sets of alignment marks corresponding to a plurality of following masks thereafter, and a plurality of sets of alignment marks corresponding to the plurality of following masks thereafter are formed on the glass substrate; and employing the plurality of sets of alignment marks on the glass substrate respectively, to perform alignment procedure and photolithography for the plurality of following masks with the plurality of sets of alignment marks on the glass substrate to form patterns; wherein corresponding to the same LCD panel area, the plurality of sets of alignment marks on the glass substrate have different position coordinates respectively. |
| US08592106B2 |
Methods of manufacturing a mask blank substrate, a mask blank, a photomask, and a semiconductor device
A before-chucking main surface shape is measured in an actual measurement region of a main surface of a substrate which has been precision-polished. Based on that shape and a shape of a mask stage (1), a simulated after-chucking main surface shape of the substrate, when a photomask (2) manufactured from the substrate is set in an exposure apparatus, is obtained. A selection is made of the substrate in which the after-chucking main surface shape has a flatness of a first threshold value or less in a virtual calculation region thereof. A calculation is performed and a selection is made of the substrate in which an after-correction main surface shape has a flatness of a second threshold value or less in the correction region. |
| US08592100B2 |
Catalyst layer for fuel cells and fuel cell using the same
Provided is a fuel cell having improved ion conductivity in the catalyst layer. The catalyst layer includes a catalytic metal, a carbon particle, and an ion exchanger. The catalytic metal is carried on the carbon particle. The ion exchanger includes a first functional group capable of being adsorbed or bound to the catalytic metal, and a second functional group providing the ion conductivity. The ion exchanger is adsorbed or bound to the catalytic metal via the first functional group. The bond between the catalytic metal and the ion exchanger includes a covalent bond, a coordinate bond or an ion bond. |
| US08592094B2 |
Membrane electrochemical generator
The present invention relates to a membrane electrochemical generator (100) characterized by improved electrical insulation and reduced volume. The membrane electrochemical generator (100) is fed with gaseous reactants and comprises a multiplicity of reaction cells (101) assembled in a filter-press configuration. Each of said reaction cells (101) is delimited by a pair of bipolar sheets (102), formed by a metallic central body (110) integrated in a frame (111) made of polymeric material. The polymeric material may be of the thermoplastic or thermosetting type and the frame (111) is laid on the metallic central body (110) by molding. |
| US08592093B2 |
Solid oxide fuel cell device
A solid oxide fuel cell (SOFC) device comprises a fuel cell assembly, a reformer, a fuel gas supply device, a reforming air supply device, a power generating air supply device, an ignition device, a temperature detection devices for detecting the temperature caused by combustion of fuel gas, and a control section for sequentially conducting a combustion operation in which fuel gas is ignited by the ignition device and combusted using the power generating air, a POX operation, an ATR operation, and an SR combination, wherein the control section determines that a flameout has occurred when the amount by which the temperature caused by combustion of fuel gas and detected by the temperature detection device drops within a predetermined time is equal to or greater than a preset, predetermined temperature drop threshold, and the predetermined temperature drop threshold is set as a plurality of predetermined temperature drop thresholds in accordance with temperature bands caused by the combustion of fuel gas, the lower the temperature induced by the combustion of fuel gas, the higher is the temperature drop threshold. |
| US08592091B2 |
Method for producing a proton-conducting, structured electrolyte membrane
In a method for producing a proton-conductive, structured electrolyte membrane, particularly for a fuel cell, a coating, which comprises at least one ion-conductive cross-linking component having at least one acid group and at least one photoactive substances interacting therewith, is applied onto a solid body surface. The coating is optically masked in that at least one region of the coating, in which the electrolyte membrane is supposed to be, is exposed such that the cross-linking component cross-links with the photoactive substances to form a polymer and/or copolymer network adhering to the solid body surface. At least one unexposed region of the coating is removed in order to structure the electrolyte membrane. |
| US08592087B2 |
Negative active material, electrode including the same, and lithium battery including electrode
A negative active material, an electrode including the same, and a lithium battery including the electrode. The negative active material has no volumetric expansion and has high solubility with respect to lithium. In addition, the negative active material is in the form of spherical particles, and thus does not require a separate granulating process. Moreover, the negative active material may enhance the capacity of a lithium battery. |
| US08592086B2 |
Negative electrode comprising an additive with a ceramic core and carbon disposed on the core for energy storage device and energy storage device including same
Disclosed is a negative electrode for an energy storage device, which includes a negative active material, and an additive including a ceramic core and carbon disposed on the surface of the ceramic core. |
| US08592085B2 |
Nickel-cobalt-maganese-based compound particles and process for producing the nickel-cobalt-manganese-based compound particles, lithium composite oxide particles and process for producing the lithium composite oxide particles, and non-aqueous electrolyte secondary battery
The present invention relates to nickel-cobalt-manganese-based compound particles which have a volume-based average secondary particle diameter (D50) of 3.0 to 25.0 μm, wherein the volume-based average secondary particle diameter (D50) and a half value width (W) of the peak in volume-based particle size distribution of secondary particles thereof satisfy the relational formula: W≦0.4×D50, and can be produced by dropping a metal salt-containing solution and an alkali solution to an alkali solution at the same time, followed by subjecting the obtained reaction solution to neutralization and precipitation reaction. The nickel-cobalt-manganese-based compound particles according to the present invention have a uniform particle size, a less content of very fine particles, a high crystallinity and a large primary particle diameter, and therefore are useful as a precursor of a positive electrode active substance used in a non-aqueous electrolyte secondary battery. |
| US08592082B2 |
Electrode assembly and secondary battery having the same
A secondary battery includes an electrode assembly, which has improved safety by reducing a density of an active material centrally positioned in the electrode assembly. In the secondary battery, an electrode assembly includes a first electrode plate, a second electrode plate and a separator between the first electrode plate and the second electrode plate, the first electrode plate including a first electrode current collector and a first active material layer on the first electrode current collector, the first active material layer including a first active material, a binder and a conductive agent, and a portion of the first active material layer at a central portion of the electrode assembly including the first active material at a lower density than a density of the first active material at a portion of the first active material layer at a peripheral portion of the electrode assembly. |
| US08592079B2 |
Rechargeable battery
Provided is a rechargeable battery capable of easily connecting a terminal and a cap plate to each other. The rechargeable battery includes; an electrode assembly having a positive electrode and a negative electrode; a case receiving the electrode assembly; a cap plate coupled with the case; first and second terminals electrically connected to the electrodes; and a connecting member electrically connecting the first terminal to the cap plate, in which the connecting member may have an elastically deformable structure. |
| US08592078B2 |
Lithium ion battery
A lithium ion battery including a lithium ion battery core, a cylindrical aluminum shell, a positive guide needle of the anode, a negative guide needle of the cathode, a rubber seal having a circular recess in the outside of the side wall, and a sealing band. The battery core is arranged within the shell. The positive and negative guide needles are led out from under the seal. The battery core together with the rubber seal is sealed in the shell via the sealing band which is molded from an insulated moldable material by rolling. The sealing band is applied only to the top portion of the shell, the side wall of the seal, and the edge of the top wall of the seal. The bottom wall of the shell is provided with a pressure relief valve. |
| US08592074B2 |
Separator and method of manufacturing the same and organic battery employing the same
An exemplary separator of the present invention includes a first layer and a second layer. The first layer has a principal body made from high fiber material. The second layer is made from chlorophyll, and is deposed on the first layer. In one embodiment, the separator comprises a third layer, where the second layer is sandwiched between the first layer and the third layer. An organic battery using the separator and a method of manufacturing the separator are also provided in the present invention. |
| US08592073B2 |
Flat-plate battery
A flat-plate battery is provided in the present invention. The flat-plate battery includes a negative-electrode layer, a first separator, a chlorophyll layer, a second separator, a positive-electrode layer, an upper plate and a lower plate. The negative-electrode layer, the first separator, the chlorophyll layer, the second separator and the positive-electrode layer are stacked together in sequence, and then are sandwiched between the upper plate and the lower plate. The flat-plate battery of the present invention can store hydrogen by the chlorophyll of the chlorophyll layer to generate electricity. Thus, the manufacturing process of the flat-plate battery is simple and economical, and only natural and non-toxic substances are used. Unlike the manufacturing process of conventional batteries, the manufacturing process of the flat-plate battery of the present invention will not cause environmental pollution even when the battery is discarded after use. |
| US08592072B2 |
Battery separator and method for producing the same, and lithium ion secondary battery and method of producing the same
A battery separator (13) of the present invention includes a porous film (12) serving as a substrate and a crosslinked polymer layer (11) supported on the porous film (12). The crosslinked polymer layer (11) contains a crosslinked polymer and inorganic particles, and is non-porous. The crosslinked polymer is obtained by reacting a reactive polymer having a functional group in its molecule with a polyfunctional compound reactive with the functional group so as to crosslink at least a part of the reactive polymer. A lithium ion secondary battery of the present invention includes a positive electrode (14), a negative electrode (15), the battery separator (13) of the present invention disposed between the positive electrode (14) and the negative electrode (15), and a non-aqueous electrolyte solution. The battery separator (13) is disposed so that the porous film (12) faces the negative electrode (15) and the crosslinked polymer layer (11) faces the positive electrode (14). |
| US08592068B2 |
Battery pack
A battery pack (1) includes: paired supporting members (35); a battery module (3, 5, 7) disposed between the supporting members (35); and a stack member (43) supporting the battery module (3, 5, 7) by linking the supporting members to each other. An extending portion (43a) protruding from the battery module (3, 5, 7) is formed by extending an end portion of the stack member (43). Accessories (12) are attached to a side surface on a side where the extending portion (43a) of the stack member (43) is disposed, the side surface being one of side surfaces of the battery pack which are provided with the paired supporting members (35). |
| US08592066B2 |
Battery assembly
A battery assembly that standardizes a protective circuit module to be commonly used for various types of bare cells. The battery assembly includes a bare cell, and an adaptor structure positioned on a first end portion of the bare cell and having a seat in which the protective circuit module is seated. The adaptor structure electrically connects the protective circuit module to the bare cell. The protective circuit module has a standardized shape operationally connectable to various types of bare cells. |
| US08592065B2 |
Rechargeable battery with a jelly roll having multiple thicknesses
The disclosed embodiments relate to the design of a battery cell with multiple thicknesses. This battery cell includes a jelly roll enclosed in a pouch, wherein the jelly roll includes layers which are wound together, including a cathode with an active coating, a separator, and an anode with an active coating. The jelly roll also includes a first conductive tab coupled to the cathode and a second conductive tab coupled to the anode. The jelly roll is enclosed in a flexible pouch, and the first and second conductive tabs are extended through seals in the pouch to provide terminals for the battery cell. Furthermore, the battery cell has two or more thicknesses, wherein the different thicknesses are created by removing material from one or more of the layers before winding the layers together. |
| US08592064B2 |
Intelligent multifunctional accumulator
An intelligent multifunctional accumulator includes a multi-pin intelligent controller, a signal emitter, a buzzer, a sensor and an accumulator with an enclosure with two layers. All the aforementioned devices are assembled inside the cavity on the back side of the top cover. Two positive terminals are set on the top surface of the accumulator enclosure. The two positive terminals can separately control the power of the engine and other electric appliances by a chip and two relays to attain an anti-theft function. The intelligent controller can be automatically locked after it is inserted into a controller box on the back side of the top cover, and cannot be taken out without the password signal of a car owner. The sensor can automatically detect the inner state of the accumulator, and the information of the state can be displayed by an LCD or sent out by using voice prompts. |
| US08592060B2 |
Perpendicular magnetic recording media having low medium noise and systems using the same
In one embodiment, a perpendicular magnetic recording medium includes a substrate, a soft-magnetic underlayer above the substrate, a seed layer above the soft-magnetic underlayer, a first intermediate layer above the seed layer, a second intermediate layer above the first intermediate layer, a recording layer above the second intermediate layer, and a protective layer above the recording layer. The second intermediate layer includes an Ru alloy having an element selected from a group consisting of: Ti in a range from about 20 at. % to about 50 at. %, Nb in a range from about 20 at. % to about 50 at. %, Al in a range from about 20 at. % to about 40 at. %, Ta in a range from about 30 at. % to about 50 at. %, and Si in a range about 20 at. % to about 40 at. %. Other magnetic media and systems using this media are described according to more embodiments. |
| US08592058B2 |
Methods of forming strontium titanate films
Embodiments of the current invention include methods of forming a strontium titanate (SrTiO3) film using atomic layer deposition (ALD). More particularly, the method includes forming a plurality of titanium oxide (TiO2) unit films using ALD and forming a plurality of strontium oxide (SrO) unit films using ALD. The combined thickness of the TiO2 and SrO unit films is less than approximately 5 angstroms. The TiO2 and SrO units films are then annealed to form a strontium titanate layer. |
| US08592052B2 |
Organic electroluminescence device
[Problem to be solved by the Invention]An organic electroluminescence device having a longer drive life is provided.[Means for solving the Problem]An organic electroluminescence device comprises, between a pair of electrodes composed of an anode and a cathode, a light emitting layer, a hole transport layer provided on the anode side of the light emitting layer, and an electron transport layer provided on the cathode side of the light emitting layer.At least one layer among the layers constituting the electron transport layer includes an electron movement suppressing material which suppresses the movement of electrons. |
| US08592049B2 |
High strength hot dip galvanized steel sheet and high strength galvannealed steel sheet excellent in shapeability and plateability
Hot dip galvanized steel sheet excellent in shapeability and plateability comprised of high strength steel sheet according to the present invention can be provided containing, by mass % about, C: 0.05 to 0.25%, Si: 0.3 to 2.5%, Mn: 1.5 to 2.8%, P: 0.03% or less, S: 0.02% or less, Al: 0.005 to 0.5%, N: 0.0060% or less and the balance of Fe and unavoidable impurities. The exemplary steel sheet can have thereon a galvanized layer containing, e.g., about Al: 0.05 to 10 mass % and Fe: 0.05 to 3 mass % and the balance of Zn and unavoidable impurities. Such exemplary hot dip galvanized steel sheet can have oxides containing Si in an average content of about 0.6 to 10 mass % at the crystal grain boundaries and in the crystal grains at the sheet steel side 5 μm or less from the interface between the high strength steel sheet and the plating layer and by the presence of Fe—Zn alloy with an average grain size of about 0.5 to 3 μm at the plating side. |
| US08592047B2 |
Binder based on carboxylic acid vinyl ethylene ester copolymer and polyolefin containing a functional monomer
The invention relates to a binding agent comprising a mixture of a carboxylic acid vinyl ethylene ester copolymer (A) and a polyolefin (B) containing a functional monomer (X), the mass ratio B/(A+B) being between 0.05 and 1. Said binder has very good adhesion properties for adhering to a number of supports in photovoltaic modules, in addition to satisfactory transparency and electrical resistivity properties for the advantageous use of the binder in said module. |
| US08592035B2 |
Adhesive composition, adhesive tape and adhesion structure
To provide a pressure-sensitive adhesive composition for a removable pressure-sensitive adhesive tape which can be, after attaching to an adherend, easily removed from the adherend by stretching the pressure-sensitive adhesive tape and does not cause adhesive transfer on the adherend or damage of the adherend. A pressure-sensitive adhesive composition comprises a cohesive component comprising a styrene-based block copolymer, and a basic component. |
| US08592026B2 |
Aircraft fuselage frame of composite material with stabilising ribs
Aircraft fuselage frame in composite material with stabilising ribs which, in at least a first sector (31), comprises a frame (9) with an omega-shaped cross-section (11) formed by a top element (23), two webs (25, 25′), two feet (27, 27′) which includes at least one internal rib (41) formed by a top element (43) joined to the top element (23) of the frame (9), a web (45), two flanges (49, 49′) joined to the webs (25, 25′) of the frame (9) and a foot (47) aligned with the feet (27, 27′) of the frame (9). The invention also relates to a manufacturing procedure for the first sector (31) of the frame with stabilised web (10) comprising steps for: a) providing a frame (9) and at least one internal rib (41) with the configurations indicated; b) joining at least said internal rib (41) to the frame (9). |
| US08592019B2 |
Heat shrink wire marker carrier
A wire marker is provided. A carrier strip includes a first layer having at least one opening, two bands applied to opposite edges of the first layer, the bands including an adhesive on at least one side, and a label secured into the opening and attached to the adhesive. At least one access perforation may be located on the first layer that is horizontal and adjacent to one side of the opening. The access perforation facilitates removal of the label from the carrier and allows for insertion of a cable through the label. A plurality of horizontal carrier perforations may further be located between each opening on the first layer to facilitate removal of the carrier strip from a printer. |
| US08592012B2 |
Recording medium
A recording medium includes, in sequence, a support, a first ink-receiving layer, and a second ink-receiving layer, in which the first ink-receiving layer contains at least one selected from an alumina, an alumina hydrate, and a fumed silica, a polyvinyl alcohol, and a boric acid, in which a mass ratio of a content of the boric acid in the first ink-receiving layer to a content of the polyvinyl alcohol in the first ink-receiving layer is 2.0% by mass or more and 7.0% by mass or less, in which the second ink-receiving layer contains a fumed silica, a polyvinyl alcohol, and a boric acid, and in which a mass ratio of a content of the boric acid in the second ink-receiving layer to a content of the polyvinyl alcohol in the second ink-receiving layer is 10.0% by mass or more and 30.0% by mass or less. |
| US08592011B2 |
Ink jet recording medium
In an ink jet recording medium having at least two ink receiving layers, the total content of boric acid, a borate, and a water-soluble zirconium salt of a lower ink receiving layer located close to a support substrate to the total content of alumina and an alumina hydrate thereof is higher than the total content of boric acid, a borate, and a water-soluble zirconium salt of an upper ink receiving layer located apart from the support substrate to the total content of alumina and an alumina hydrate thereof. |
| US08592009B2 |
Liquid crystal display device and manufacturing method thereof
A liquid crystal display device superior in mass productivity and improved image quality with a higher contrast ratio by decreasing the occurrence of defective display due to the disorder of the initial liquid crystal alignment and realizing stable alignment of liquid crystals, comprising: a pair of substrates 101 and 102, at least one of which is transparent; a liquid crystal layer 110′ disposed between the pair of substrates; a group of electrodes formed on at least one of the pair of substrates to apply an electric field to the liquid crystal layer; plural active elements 115 connected to the group of electrodes; and an orientation control film 109 disposed on at least one of the pair of substrates, wherein said orientation control film made of a photosensitive polyimide, a polyamide acid ester and a polyamide acid is given orientation control ability by being irradiated with substantially linearly polarized light. |
| US08592008B2 |
Compound, liquid crystal composition and liquid crystal display device
To provide a liquid crystal composition satisfying at least one of characteristics such as a high maximum temperature of a nematic phase, a low minimum temperature thereof, a small viscosity, a large optical anisotropy, a large dielectric anisotropy, a large specific resistance, a large elastic constant, a high stability to ultraviolet light and heat, or a liquid crystal composition having a suitable balance regarding at least two of the characteristics; and an AM device having a short response time, a large voltage holding ratio, a large contrast ratio, a long service life and so forth; wherein a liquid crystal composition has a nematic phase and contains a specific compound having a high maximum temperature and a large dielectric anisotropy as a first component, and a specific compound having a small viscosity as a second component, and may contain a specific compound having a large dielectric anisotropy as a third component. |
| US08592002B2 |
Method for the production of single-and/or multiple-coated substrates
A process for the production of singly and/or multiply coated paper and/or board, except for photographic papers and self-adhesive labeling papers, which are particularly suitable for printing, packaging and inscription, is described. The substrate, for example base paper or board, is coated once or several times with a free-falling liquid curtain, the coating liquid having in particular an extensional viscosity of from 1 to 1000 Pa·s at a Hencky strain of from 1 to 15. |
| US08592000B2 |
Multilayer coating film-forming method
This invention relates to a method of forming multilayer coating film of excellent appearance by 3-coat-1-bake system, comprising successively applying onto a coating object, a water-based intermediate paint, water-based base paint and a clear paint; and then simultaneously heat-curing the resulting 3-layered coating film. |
| US08591999B2 |
Coating compositions
The invention relates to coatings for leather. In particular it relates to top coats for leather. It provides a leather coating composition comprising an organic synthetic resin in aqueous dispersion and an organopolysiloxane, characterized in that the organopolysiloxane is present in aqueous emulsion and comprises a silicone resin having an empirical formula: (I) where •R is a monovalent organic group having 1-30 carbon atoms, •Z is hydrogen or an alkyl group having 1-4 carbon atoms, •x has a value from 0.75 to 1.7, and •y has a value from 0.1 to 2.0, and having a viscosity of from 1 to 4000 mPa·s at 25° C. We have found that the use of a silicone resin according to the invention greatly increases the abrasion resistance, as measured by the Taber method, of leather coated with the coating composition. R x Si ( OZ ) y ( O ) 4 - x - y 2 ( I ) |
| US08591997B2 |
Process for preparing structured organic films (SOFS) via a pre-SOF
A processes for preparing structured organic film (SOF) comprising a plurality of segments and a plurality of linkers arranged as a covalent organic framework, wherein the structured organic film may be a multi-segment thick structured organic film. |
| US08591995B2 |
Method for transferring freshly coated golf ball
There are provided a golf ball having a paint coating that is prevented from being unevenly distributed over the ball surface, and a method and apparatus for manufacturing the golf ball. The method for manufacturing the golf ball comprises the steps of coating the surface of the golf ball with paint in a painting section; transferring the coated golf ball from the painting section to a drying section; and drying the coated golf ball in the drying section. The transferring step comprises attaching the coated golf ball to a moving unit by suction in the painting section; moving the moving unit to which the golf ball is attached by suction from the painting section to the drying section; and blowing gas to the golf ball toward the direction opposite to the suction direction for attaching the golf ball to release the golf ball from the moving unit in the drying section. |
| US08591993B2 |
Epitaxial wafer manufacturing apparatus and manufacturing method
An epitaxial wafer manufacturing apparatus including: a chamber; a gas introduction port provided in the chamber and configured to introduce a reaction gas into the chamber; a gas exhaust port provided in the chamber and configured to exhaust the reaction gas from inside the chamber; a rotating unit provided inside the chamber; a wafer holder provided in an upper portion of the rotating unit and configured to hold a wafer; and an annular flow-regulating wall being spaced from the rotating unit and the wafer holder, the annular flow-regulating surrounding the upper portion of the rotating unit and a upper portion of the wafer holder, and the annular flow-regulating expanding downward. The flow-regulating wall has an upper end being located above the wafer holder. The upper end has a smaller inner diameter than an outer periphery of the wafer holder. The flow-regulating wall has a lower end being located below an upper surface of the rotating unit. The lower end has a larger inner diameter than an outer periphery of the rotating unit. |
| US08591991B2 |
Fabrication method and fabrication apparatus for fabricating metal oxide thin film
A fabrication method for fabricating a metal oxide film introduces H2 gas and O2 gas or, H2O2 gas, into a catalytic reactor to make contact with a catalyst to generate H2O gas. The H2O gas that is generated is jetted from the catalytic reactor to react with a metal compound gas, to thereby deposit the metal oxide thin film on a substrate and fabricate the metal oxide thin film. |
| US08591990B2 |
Microfiber supported metal silicide nanowires
An arrangement of elongated nanowires that include titanium silicide or tungsten silicide may be grown on the exterior surfaces of many individual electrically conductive microfibers of much larger diameter. Each of the nanowires is structurally defined by an elongated, centralized titanium silicide or tungsten silicide nanocore that terminates in a distally spaced gold particle and which is co-axially surrounded by a removable amorphous nanoshell. A gold-directed catalytic growth mechanism initiated during a low pressure chemical vapor deposition process is used to grow the nanowires uniformly along the entire length and circumference of the electrically conductive microfibers where growth is intended. The titanium silicide- or tungsten silicide-based nanowires can be used in a variety electrical, electrochemical, and semiconductor applications. |
| US08591989B2 |
SiCN film formation method and apparatus
A method for forming an SiCN film on target substrates placed in a process field inside a process container repeats a unit cycle a plurality of times to laminate thin films respectively formed, thereby forming the SiCN film with a predetermined thickness. The unit cycle includes performing and suspending supply of a silicon source gas, a nitriding gas, and a carbon hydride gas respectively from first, second, and third gas distribution nozzles to the process field. The unit cycle does not turn any one of the gases into plasma but heats the process field to a set temperature of 300 to 700° C. with the supply of the carbon hydride gas performed for a time period in total longer than that of the supply of the silicon source gas, so as to provide the SiCN film with a carbon concentration of 15.2% to 28.5%. |
| US08591985B2 |
Systems and methods affecting profiles of solutions dispensed across microelectronic topographies during electroless plating processes
A method is provided which includes dispensing a deposition solution at a plurality of locations extending different distances from a center of a microelectronic topography each at different moments in time during an electroless plating process. An electroless plating apparatus used for the method includes a substrate holder, a moveable dispense arm, and a storage medium comprising program instructions executable by a processor for positioning the moveable dispense arm. Another method and accompanying electroless deposition chamber are configured to introduce a gas into an electroless plating chamber above a plate which is suspended above a microelectronic topography and distribute the gas to regions extending above one or more discrete portions of the microelectronic topography. An exemplary microelectronic topography resulting from the aforementioned methods and apparatuses includes a layer having distinct regions each including a comparatively different thickness and comparatively different concentrations of one of the one or more elements. |
| US08591983B2 |
Bypass protection for protein and starch in animal feed
To increase the efficiency of utilizing protein, lipid and starch by ruminants, feed and urea-formaldehyde polymer are mixed in quantities suitable for a crosslinking reaction. The mixture is heated at a temperature, moisture content and time sufficient to covalently bond the urea-formaldehyde polymer with the proteins and starches to thereby protect the proteins, starches and contained lipids from degradation by rumen microbes. |
| US08591974B2 |
Delivery system for two or more active components as part of an edible composition
A delivery system for inclusion in an edible composition is formulated to have at least two active components with an encapsulating material for managing the release of the two actives relative to each other when used in an edible composition. |
| US08591973B2 |
Delivery system for active components and a material having preselected hydrophobicity as part of an edible composition
A delivery system for inclusion in an edible composition is formulated to have at least one active component with an encapsulating material for delivering the active component when the active component is included in an edible composition and the edible composition is consumed. |
| US08591968B2 |
Edible composition including a delivery system for active components
A delivery system for inclusion in an edible composition is formulated to have at least one active component with an encapsulating material for delivering the active component upon consumption of the edible composition. |
| US08591967B2 |
Biodegradable chewing gum comprising at least one high molecular weight biodegradable polymer
The invention relates to a chewing gum comprising at least one biodegradable polymer, wherein the molecular weight of said polymer is at least 105000 g/mol (Mn). According to the invention, it has moreover been realized that this problem may be effectively dealt with by increasing the molecular weight of at least one of the biodegradable polymers in the chewing gum when compared to conventional chewing gum polymers and thereby increasing the robustness of the chewing gum with respect to softeners, emulsifiers and e.g. flavor. |
| US08591966B2 |
Composition containing oils of chamomile flower and black cumin with reduced endotoxins
A composition comprising an aqueous extract of camomile flowers is useful for the treatment of a proliferative and/or inflammatory condition. |
| US08591962B2 |
Composition for preventing and treating influenza-virus-induced diseases
The present invention relates to a medicinal extract useful for preventing and treating influenza-virus-induced diseases, and to a pharmaceutical composition and health food including same. Derived from natural ingredients, the medicinal extract of the present invention is safe for humans, and can be used to prevent, treat, and alleviate symptoms of diseases induced by various strains of influenza viruses. |
| US08591955B2 |
Orally rapidly disintegrating tablet that contains two or more types of particles
The present invention provides an orally rapidly-disintegrating tablet comprising at least two particles. Regarding medicaments with unpleasant taste, the present invention provides a tablet comprising such medicament having a suitable hardness so that the tablet can be handled without any difficulty in the period from the formulation of the tablet to the administration thereof (in particular, a tablet which can maintain the hardness thereof when it is stored under a humidified condition); a small size; no unpleasant taste; a pleasant feeling in a mouth after administration; and an excellent disintegration character in the oral cavity and an excellent dissolution character in the gastrointestinal tract. |
| US08591953B2 |
Drug carrier and drug carrier kit for inhibiting fibrosis
An astrocyte-specific drug carrier containing a retinoid derivative and/or a vitamin A analog as a constituent; a drug delivery method with the use of the same; a drug containing the same; and a therapeutic method with the use of the drug. By binding a drug carrier to a retinoid derivative such as vitamin A or a vitamin A analog or encapsulating the same in the drug carrier, a drug for therapeutic use can be delivered specifically to astrocytes. As a result, an astrocyte-related disease can be efficiently and effectively inhibited or prevented while minimizing side effects. As the drug inhibiting the activity or growth of astrocytes, for example, a siRNA against HSP47 which is a collagen-specific molecule chaperone may be encapsulated in the drug carrier. Thus, the secretion of type I to type IV collagens can be inhibited at the same time and, in its turn, fibrosis can be effectively inhibited. |
| US08591949B2 |
Aqueous compositions comprising a chemical microgel associated with an aqueous polymer
The invention concerns an aqueous composition comprising particles of a water-soluble or water-dispersible chemical microgel, associated with at least a water-soluble or water-dispersible crosslinking polymer, differing in composition from the particles; the amount of chemical microgel particles ranging between 0.05 to 40% by dry weight of the composition and the amount of crosslinking polymer being such that the viscosity of the composition is at least three times higher than that of an aqueous solution of chemical microgel particles and than that of an aqueous solution of crosslinking polymer, in similar conditions. The invention also concerns said composition, its use and formulations comprising same. |
| US08591947B2 |
Dual controlled release dosage form
A dosage form that provides a controlled release of at least two different active agents is provided. Particular embodiments include a dosage form that provides therapeutically effective levels of a first active agent and a second active agent in a mammal for an extended period of time following oral administration. An osmotic device containing a bi-layered core is provided. The osmotic device provides a dual controlled release of both drugs from the core. The layers of the core are in stacked, substantially concentric or substantially eccentric arrangement. |
| US08591945B2 |
Pregelatinized starch in a controlled release formulation
The present invention concerns the use of pregelatinized starch to prevent dose-dumping from a hydrophilic controlled release formulation. It also concerns a hydrophilic controlled release formulation, more in particular a hydrophilic controlled release matrix formulation, and solid dosage forms prepared therefrom, preferably for once daily oral administration. The hydrophilic controlled release formulation comprises pregelatinized starch, one or more active ingredients, one or more viscous hydrophilic polymers and optionally pharmaceutically acceptable formulating agents. Preferred hydrophilic polymers include hydroxypropyl cellulose and hydroxypropyl methylcellulose. |
| US08591944B2 |
Solid dispersion formulations and methods of use thereof
The present invention relates to formulations and methods for increasing the bioavailability of 1-(4-benzhydrylpiperazin-1-yl)-3,3-diphenylpropan-1-one, 1-(3,3-diphenylpropanoyl)piperazine, or a salt thereof. In particular, the formulation can include one or more pharmaceutically acceptable matrix polymers to form a solid dispersion, e.g., a spray dried dispersion or a hot melt extrusion. |
| US08591940B2 |
Method of treating scar tissue
A method of treating scar tissue by applying a composite sheet for delivering therapeutic agents to the skin is disclosed. The composite sheet comprises a flexible porous polymer for holding and releasing the therapeutic agent in a polymer enrobing material. Microchannels pass through the polymer enrobing material and flexible porous polymer to promote the release of the therapeutic agent. The composite sheet is capable of releasing the therapeutic agent for periods of about 0 to about 30 days. |
| US08591938B2 |
Liquid compositions of calcium acetate
The invention relates to an aqueous liquid composition of calcium acetate, sweetener, and taste masking agent. Also provided is a method for binding phosphorus within the gastrointestinal tract of an individual by administering to the individual an aqueous solution of at least calcium acetate. |
| US08591925B2 |
Lipophilically surface-treated powder having easy dispersability and cosmetic blended with such a powder
Provided is a surface-treated powder, in which a powder is treated with a surface-treating agent composed of a mixture A+B including A: an alkyl alkoxy silane of a general formula (1): (CnH2n+1)aSi(OCmH2m+1)b and B: one kind of a compound or two or more kinds of compounds selected from a reactive organo silicone of the following general formula (2): (R13SiO)(R12SiO)p(SiR23) and a C12 to C22 saturated or unsaturated branched fatty acid. In the general formula (1), n is an integer of 1 to 18, m is an integer of 1 to 3, a, b represent an integer of 1 to 3, and a+b=4. In the general formula (2), R1s mutually independently represents a lower alkyl group having 1 to 4 carbon atoms or a hydrogen atom or a hydrogen atom, respectively, R2 is any of an amino group, a hydrogen atom, a hydroxyl group and a C1-C4 lower alkoxy group, and p is an integer of 1 to 300. |
| US08591923B2 |
Cosmetic compositon comprising a (thio)urethane/(thio)urea copolymer capable of forming at least 3 hydrogen bonds, and a method of cosmetic treatment
The present application relates to cosmetic compositions comprising, in a physiologically acceptable medium, a copolymer having a (thio)urethane/(thio)urea polymer skeleton, resulting from the reaction: of a first monomer having at least two polymerizable groups, which may be identical or different, chosen from —N═C═O and —N═C═S, of a monomer (b1) having at least two polymerizable groups with a labile hydrogen, of a monomer (b2), different from monomer (b1), having at least two polymerizable groups with a labile hydrogen, with at least one of these monomers comprising at least one junction group (A), capable of forming at least 3 hydrogen bonds. The disclosure also relates to a method of cosmetic treatment of keratinous materials, comprising the application of a cosmetic composition as defined above on said materials. |
| US08591920B2 |
Stable lipophilic emulsions for acrylic coating and method of making
Emulsions of lipophiles such as glycerol monostearate which are compatible with acrylic copolymer emulsions are made stable by using an emulsion stabilizer such as polysorbate 80 in an amount by weight between 1% and 5% of the lipophile and homogenizing the emulsion wherein the emulsion micelles are less than 50 microns. The ability to make a stable emulsion of a lipophile is important in the coating process as it enables preparation and shipment of the lipophilic emulsion to the coater rather than the preparation of a lipophilic emulsion at the time of the coating process which involves a heating and cooling process. |
| US08591919B2 |
Synergistic mixture of beta-galacto-oligosaccharides with beta-1,3 and beta -1,4/1,6 linkages
The present invention relates to a nutritional composition comprising at least two different beta-galacto-oligosaccharides (BGOS) A and B wherein the majority of linkages between two galactose residues in BGOS A are beta 1,4 and/or beta 1,6, and the majority of linkages between two galactose residues in BGOS B are beta 1,3. Such mixtures show superior effects on the immune system and are particularly suitable for infant nutrition. |
| US08591918B2 |
Mycobacterial mutants inducing IL-12
Provided are mycobacteria deleted in at least a portion of a region 3 ESAT-6-like gene cluster. Also provided are mycobacteria comprising a mutation in an roc-1 gene. Additionally, vaccines comprising these mycobacteria are provided. Further provided are methods of making a recombinant mycobacterium, methods of inducing an immune response in a mammal, methods of inhibiting IL-12 production in a mammal, and methods of stimulating IL-12 production in a mammal. Vaccine adjuvants are also provided, as are methods of inducing immunity to a target antigen in a mammal. |
| US08591915B2 |
Plant-derived vaccines against respiratory syncytial virus
A plant-derived vaccine against respiratory syncytial virus (RSV) is disclosed. The vaccine includes an immunogenic complex that includes plant cells transformed with a chimeric gene containing a nucleotide sequence adapted for protein expression in plants and an RSV coding sequence that encodes an antigenic protein of RSV. Also disclosed are methods of making the plant-derived vaccine of the invention, as well as transgenic plants, transgenic plant cells, and nucleic acid constructs useful in immunizing a mammal against RSV. |
| US08591912B1 |
Algae extraction process
A method of extracting oil from algae by drying algae paste to a predetermined moisture content, contacting the algae paste with a polar solvent to make an algae-solvent solution and extracting oils from the algae paste into a solvent-oil solution, and separating extracted algae from the solvent-oil solution. An oil of whole and unhydrolyzed phospholipids, whole and unhydrolyzed glycolipids, lysolipids, and carotenoids extracted by the above method. An omega-3 fatty acid of docosahexanoic acids (DHAs) and eicosapentaenoic acids (EPAs) extracted from the above method. Isolated nutraceutical grade and pharmaceutical grade oil derived from algae and being free of toxins extracted by the above method. Isolated oil derived from algae including at least one omega-3 fatty acid of DHA and EPA at least partially in the form of whole and unhydrolyzed phospholipids and whole and unhydrolyzed glycolipids extracted by the above method. |
| US08591910B2 |
Chemically programmable immunity
The present invention is related to methods and compositions that are capable of immediately immunizing a human or animal against any molecule or compound. The present invention comprises an immunity linker molecule with at least two sites; (1) a first binding site that binds to an immune system molecule in a human or animal that has been preimmunized against the first binding site, and (2) one or more second binding sites that bind specifically to a desired compound or molecule. The first binding site and the second binding site(s) are linked by a linker portion of the molecule. |
| US08591909B2 |
Recombinant carrier molecule for expression, delivery and purification of target polypeptides
Recombinant carrier molecules having amino acid sequences from thermostable enzymes and methods of use for expression, recovery and delivery of foreign sequences (peptides and polypeptides) produced in different systems (bacteria, yeast, DNA, cell cultures such as mammalian, plant, insect cell cultures, protoplast and whole plants in vitro or in vivo are provided. The recombinant carrier molecule using sequences from lichenase B (Lic B) were also made and used as part of carrier protein to express, recover and deliver a variety of target polypeptides of interest. |
| US08591903B2 |
Inhibition of TACE or amphiregulin for the modulation of EGF receptor signal transactivation
The present invention relates to the modulation of transactivation of receptor tyrosine kinases by G protein or G protein-coupled receptor (GPCR) mediated signal transduction in a cell or an organism comprising inhibiting the activity of the metalloprotease TACE/ADAM17 and/or the activity of the receptor tyrosine kinase ligand amphiregulin. |
| US08591902B2 |
Antibody binding to lysophosphatidylglucoside, and composition comprising the same
In order to identify a factor demonstrating a repellent effect on axon extension of a neuron, lysophosphatidylglucoside (LPG) has been found to have an activity as a chemorepellent effect on axon guidance of a DRG sensory neuron specific to a neuron expressing TrkA, an NGF receptor.In addition, it has been found out that suppressing the function of LPG makes it possible to suppress a repellent effect of LPG on axon extension of a neuron expressing TrkA. A molecule capable of suppressing the function of LPG can be a composition promoting repairing of a neural circuit in neuronal damages and the like. |
| US08591899B2 |
Diagnosis of Bacillus anthracis infection based on detection of bacterial secreted biomarkers
A novel and rapid diagnostic method for anthrax infection is provided. Three B. anthracis gene products are described, as well as antibodies against the same, which may be used for the detection and monitoring of anthrax infection. Kits for the diagnosis of anthrax are also provided. |
| US08591896B2 |
Chemokine receptor binding polypeptides
The present invention relates to polypeptides directed against or specifically binding to chemokine receptor CXCR2 and in particular to polypeptides capable of modulating signal transduction from CXCR2. The invention also relates to nucleic acids, vectors and host cells capable of expressing the polypeptides of the invention, pharmaceutical compositions comprising the polypeptides and uses of said polypeptides and compositions for treatment of diseases involving aberrant functioning of CXCR2. |
| US08591895B2 |
Combinations for the treatment of diseases involving cell proliferation
Disclosed are pharmaceutical compositions for the treatment of diseases which involve cell proliferation. Also disclosed are methods for the treatment of said diseases, comprising co-administration of a compound 1 of Formula (I) wherein the groups L, R1, R2, R3, R4 and R5 have the meanings given herein and of an effective amount of an active compound 2 and/or co-treatment with radiation therapy, in a ratio which provides an additive and synergistic effect, and to the combined use of a compound 1 of Formula (I) and of an effective amount of an active compound 2 and/or radiotherapy for the manufacture of corresponding pharmaceutical combination preparations. |
| US08591894B2 |
Humanized antibodies that sequester amyloid beta peptide
A method to treat conditions characterized by formation of amyloid plaques both prophylactically and therapeutically is described. The method employs humanized antibodies which sequester soluble Aβ peptide from human biological fluids or which preferably specifically bind an epitope contained within position 13-28 of the amyloid beta peptide Aβ. |
| US08591893B2 |
Paratope and epitope of anti-mortalin antibody
The amino acid sequences of paratope regions involved in internalizing function of an anti-mortalin antibody into tumor cells were determined for the L-chain and H-chain variable regions of cellular internalizing anti-mortalin antibodies and non-internalizing anti-mortalin antibodies. Cancer-cell-specific drug delivery is provided by using the mortalin-binding activity of a single-chain antibody (scFv) wherein L-chain and H-chain variable regions both having the paratope region are linked together via a peptide linker. Also, the sequence of 6 amino acids of an epitope to be recognized by an anti-mortalin antibody having the internalizing function was determined. With the use of an expression vector comprising a nucleic acid that encodes the epitope, an agent for accelerating internalization of a mortalin antibody, a drug bound thereto, and the like into cancer cells is provided. |
| US08591891B2 |
Monoclonal antibodies against ANGPTL4
Monoclonal antibodies that specifically bind to ANGPTL4 are provided. Monoclonal antibodies that neutralize at least one activity of ANGPTL4 are provided. Methods of treating a disorder of lipid metabolism using neutralizing monoclonal antibodies are provided. |
| US08591889B2 |
Human monoclonal antibodies specific for CD22
Disclosed herein are isolated human monoclonal antibodies that specifically bind human CD22 with a dissociation constant (Kd) of 25 nM or less. Nucleic acids encoding these antibodies, expression vectors including these nucleic acid molecules, and isolated host cells that express the nucleic acid molecules are also disclosed. The antibodies can be used to detect human CD22 in a sample. In some cases, CD22 is soluble CD22. Methods of diagnosing a B-cell malignancy, or confirming a B-cell malignancy diagnosis, are disclosed herein that utilize these antibodies. Methods of treating a subject with a B-cell malignancy are also disclosed. |
| US08591885B2 |
Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
Biocompatible intraocular drug delivery systems include a carbonic anhydrase inhibitor therapeutic agent and a polymeric component in the form of an implant, a microparticle, a plurality of implants or microparticles, and combinations thereof. The therapeutic agent is released in a biologically active form, for example, the therapeutic agent may retain its three dimensional structure when released into an eye of a patient, or the therapeutic agent may have an altered three. The implants may be placed in an eye to treat or reduce the occurrence of one or more ocular conditions, such as retinal damage, including glaucoma and proliferative vitreoretinopathy among others. |
| US08591881B2 |
Chimeric Newcastle disease viruses and uses thereof
Described herein are chimeric Newcastle disease viruses engineered to express a heterologous interferon antagonist and compositions comprising such viruses. The chimeric Newcastle disease viruses and compositions are useful in the treatment of cancer. |
| US08591874B2 |
Inhibition of mammalian hair growth
The present invention relates to a topical skin care composition containing a safe and effective amount of a skin care active comprising agmatine, and its salt; a safe and effective amount of a first additional skin care active selected from the group consisting of BHT or BHA, hexamidine, cetyl pyridinium chloride, green tea catechins, phytosterols, ursolic acid, compounds derived from plant extracts, their salts and derivatives; and a dermatologically acceptable carrier for the agmatine composition. The present invention also relates to methods of using such agmatine compositions to regulate hair growth and the condition of mammalian skin. The methods generally comprise the step of topically applying the composition to the skin of a mammal needing such treatment, a safe and effective amount of such compositions. |
| US08591867B2 |
Oral preparation system
An oral preparation of the present invention contains a multi-composition system including a calcium ion supplying compound; a fluoride ion supplying compound a polyolphosphate ion supplying compound; and, a monofluorophosphate ion supplying compound, wherein the calcium ion supplying compound and the fluoride ion supplying compound are separated within the oral preparation. |
| US08591866B2 |
Formulations decreasing particle exhalation
Formulations have been developed for pulmonary delivery to treat or reduce the infectivity of diseases such as viral infections, especially tuberculosis, SARS, influenza and respiratory synticial virus in humans and hoof and mouth disease in animals, or to reduce the symptoms of allergy or other pulmonary disease. Formulations for pulmonary administration include a material that significantly alters physical properties such as surface tension and surface elasticity of lung mucus lining fluid, which may be isotonic saline and, optionally, a carrier. The formulation may be administered as a liquid solution, suspension, aerosol, or powder where the particles consist basically of an osmotically active solute. Drugs, especially antivirals or antibiotics, may optionally be included with the formulation. These may be administered with or incorporated into the formulation. |
| US08591865B2 |
Renal function analysis method and apparatus
A method for measuring a glomerular filtration rate of a mammalian subject comprises a source of reporter and marker fluorescent molecules. The fluorescent molecules are introduced into the vascular system of the mammalian subject. Over a period of time, a measurement of the intensities of the reporter and marker fluorescent molecules is taken. A ratio is calculated to determine the glomerular filtration rate. |
| US08591863B2 |
Compositions against cancer antigen LIV-1 and uses thereof
Described herein are methods and compositions that can be used for diagnosis and treatment of cancer. |
| US08591861B2 |
Hydrogenating pre-reformer in synthesis gas production processes
A production process includes combining a first feed stream and a second feed stream to produce, in a pre-reforming reactor, a first product stream comprising CH4 and H2O; wherein the first feed stream contains a mixture of H2 and at least one selected from the group consisting of hydrocarbons having two or more carbon atoms and alcohols having two or more carbon atoms, and the mixture has a hydrogen stoichiometric ratio (λ) of at least 0.1, and the second feed stream contains steam; feeding the first product stream into a reforming reactor; and reacting the first product stream in the reforming reactor to produce a second product stream containing CO and H2; and a catalyst for use in the process. Conversion of the second product stream to synthetic crude, methanol, higher alcohols, and/or DME may also be undertaken. Yet further conversion of a synthetic crude to lubricants, diesel and the like, and/or the alcohols/DME to gasoline, olefins, and/or other oxygenates may also be included. |
| US08591856B2 |
Single crystal diamond electrochemical electrode
An electrolytic cell includes a container for holding an electrolyte. A conductively doped single crystal diamond anode electrode is positioned to be disposed within the electrolyte, as is a conductive cathode electrode. Conductors are coupled to the electrodes for coupling to a power supply. An electrolyte inlet and an electrolyte outlet are coupled to the container for causing electrolyte to flow past the electrodes. The anode electrode is downstream from the cathode electrode in one embodiment, such that an electrolyte comprising water is purified by generation of oxygen and/or ozone. |
| US08591847B2 |
Method for removing hydrogen sulfide from gaseous stream at normal temperature
A wet desulfurizing method for removal of H2S from gaseous stream at normal temperature, the method including: (a) contacting and reacting the gaseous stream containing H2S with a suspension containing desulfurizer in a desulfurization reactor; (b) leading the suspension containing waste agent produced by desulfurizing of desulfurizer after the reaction in step (a) to a regenerative reactor, and regenerating the waste agent using an oxygen-containing gas; (c) leading the suspension containing desulfurizer regenerated in step (b) to the desulfurization reactor in step (a), and contacting and reacting with the gaseous stream containing H2S. A simple method for removing hydrogen sulfide from gas at room temperature and normal pressure, which features high desulfurization rate and low cost. |
| US08591844B1 |
Start up catalyst heating
Systems and methods are described for reducing the start-up time of flue gas conditioning processes. Such processes can include a gas removal unit configured to selectively remove a reactive gas from a flue gas stream using a catalyst and reagent to produce a scrubbed stream that is substantially depleted of the reactive gas. A heating device can advantageously be used upstream of the gas removal unit to thereby preheat the catalyst to an operational temperature and thereby reduce the start-up time of the process. |
| US08591841B2 |
Microreactor system
In relation to a microreactor, and also a microreactor system applying the same therein, not producing any dead volume therein, and thereby achieving a high level of mixing properties even at a low solution flow rate and having a simple structure thereof, disclosed herein are a microreactor and microreactor system, comprising a channel for mixing up at least two (2) types of fluids, and thereby conducting mixing/reacting of fluids by conducting the mixing/reacting of the fluids at least one (1) time, i.e., being suitable for so-called a multi-step reaction. |
| US08591831B2 |
Chip for analyzing fluids
A fluid analysis chip includes a channel formed within the chip. The chip includes a sample inlet and a sample outlet communicating with an outside of the chip, where the sample inlet and the sample outlet communicate with each other through the closed channel. An expanding part of the channel is formed in a longitudinal direction of the channel in such a manner that a pair of inner walls of the channel define an inner surface of the expanding part, and the expanding part has a larger sectional area than the channel. |
| US08591825B2 |
Extraction apparatus
An extraction apparatus capable of continuously and efficiently extracting a biological substance is provided. Multiple rotation discs are utilized in the extraction apparatus to significantly improve the efficiency of extracting the biological substance by using an extraction solvent. Specifically, when the extraction solvent is applied to extract lipids from microalgae, retention time of the microalgae in the extraction solvent can be significantly increased, and solubility of the microalgal lipids in the extraction solvent can be improved. Hence, the efficiency of extracting the lipids from the microalgae by using the extraction solvent can be enhanced. On the other hand, owing to the improvement of the efficiency of extracting the lipids from the microalgae, the amount of the extraction solvent can be reduced, and production costs can be reduced as well. |
| US08591822B2 |
Ozone generating apparatus
An ozone generating apparatus for making a temperature distribution in a dielectric tube more uniform including a sealed vessel, two tube sheets made of a conductive metal plate having a hole formed therein which are provided at a predetermined interval to divide the inside of the sealed vessel into three spaces; a metal tube formed so as to connect holes of the tow tube sheets, a dielectric tube which is inserted into the inner part of a dielectric tube so as to have a predetermined gap between an outer wall an inner wall of a metal tube and a metal electrode formed inside the dielectric tube. An alternating current voltage is applied between the tube and electrode, a gas including oxygen flowing in a gap is discharged to generate ozone, and a discharge suppressing member is provided at a part of the gap facing a tube sheet. |
| US08591818B2 |
Gas permeable chemochromic compositions for hydrogen sensing
A (H2) sensor composition includes a gas permeable matrix material intermixed and encapsulating at least one chemochromic pigment. The chemochromic pigment produces a detectable change in color of the overall sensor composition in the presence of H2 gas. The matrix material provides high H2 permeability, which permits fast permeation of H2 gas. In one embodiment, the chemochromic pigment comprises PdO/TiO2. The sensor can be embodied as a two layer structure with the gas permeable matrix material intermixed with the chemochromic pigment in one layer and a second layer which provides a support or overcoat layer. |
| US08591809B2 |
Substrate transfer container, gas purge monitoring tool, and semiconductor manufacturing equipment with the same
A substrate transfer container comprises a housing including a plurality of substrate slots positioned within a gas chamber having an interior environment. Each substrate slot accommodates a substrate undergoing a substrate manufacturing process, the interior environment of the gas chamber being selectively sealed from an exterior environment. A detection unit at the housing is constructed and arranged to detect an environmental property of the interior environment of the gas chamber, and to generate a detection signal in response. A signal transmission module at the housing is configured to wirelessly transmit a detection signal received from the detection unit. |
| US08591808B2 |
Aerosol
A nebulant suitable for sterilization comprising finely divided liquid droplets suspended in a gas, said droplets including a solute, which is advantageously hydrogen peroxide and a solvent, for example water, wherein the droplets have a concentration of greater than 60 wt % of solute and an average diameter of less than 1.0 micron, preferably less than 0.8 microns. Sterilization using the nebulant may be carried out in suitably adapted apparatus by nebulizing a solution comprising a sterilizing agent in a solvent to form a nebulant of finely divided particles of the solution in a gas stream, said solution including a solvent having a lower boiling point than the sterilizing agent; subjecting the nebulant to energy of a kind and for a duration sufficient to vaporize solvent in preference to sterilizing agent, whereby to increase the concentration of the agent in the nebulant particles; removing the solvent vaporized from the gas stream at or above atmospheric pressure and, if necessary, cooling the nebulant to below 70° C.; and exposing a surface to be sterilized to the nebulant of concentrated sterilizing agent for a time sufficient to sterilize the surface. |
| US08591804B2 |
Multi-component composition metal injection molding
A method of metal injection molding on an injection molding machine having a heated barrel with an increasing temperature gradient is disclosed. A first step includes providing a metal alloy feedstock including a first component having a first melting point and a second component having a second melting point that is higher than the first melting point, the first melting point and the second melting point selected to match the temperature gradient of the heated barrel of the injection molding machine. A second step includes feeding the metal alloy feedstock into the injection molding machine. A third step includes melting the metal alloy feedstock within the heated barrel of the injection molding machine. A fourth step includes maintaining the percentage of solids to liquids in the metal alloy feedstock of the first component and second component within a processable range of about 5% to about 30%. |
| US08591803B2 |
Process for producing components consisting of magnesium or magnesium alloy by sintering
The present invention relates to a process for producing components consisting of magnesium or magnesium alloy by sintering. This process makes it possible, for the first time, to produce components consisting of magnesium or magnesium alloy which provide outstanding elasticity together with a sufficient strength. Materials of this type can be used as biocompatible endosseous implant materials. |
| US08591799B2 |
Methods for blow molding solid-state cellular thermoplastic articles
A process for producing cellular thermoplastic articles. The process comprises the steps of treating a solid parison made from a thermoplastic material with a saturating gas at an elevated pressure for a period of time to provide a gas-saturated parison; heating the gas-saturated parison to prepare a cellular parison; placing the cellular parison in a mold; and blowing a molding gas into the cellular parison to expand the cellular parison into the shape of the mold to provide a shaped cellular article. |
| US08591798B2 |
Method for fastening an accesory in a plastic fuel tank
Method for stake-fastening an accessory (4) into a plastic fuel tank, whereby:—the accessory (4) is equipped with at least one orifice (5) which passes right through the accessory (4); —at least some of the plastic of which the wall of the tank (1) is made is melted; and—some of the molten plastic is forced through the orifice (5) of the accessory without becoming detached from the remainder of the molten plastic; —the protruding molten plastic is given an appropriate shape (8) to obtain a self-formed plastic rivet, and is left to solidify; the size and shape of the orifice (5) and/or of the solidified plastic (8) being such that the accessory (4) is mechanically fastened to the tank by at least some of the solidified plastic (8), the stake-fastening of the accessory (4) occurring at the time of manufacture of the tank (1) through the moulding of a split or at least two-part parison. |
| US08591794B2 |
Method and device for producing a nanopatterned disc
A method of producing a nanopattern on an upper side and a lower side of a disc. |
| US08591793B2 |
Press felt for paper machine and method and device for producing said felt
The invention relates to a press felt for use in the press section of a paper machine. Said felt comprises a nonwoven layer lying on one of its surfaces, the surface of said layer being connected and fixed to the felt by a thermoplastic binding material. According to the invention, the surface of the nonwoven layer is smoothed by the application of pressure from a smooth surface during the cooling of said layer surface from a temperature in excess of the melting temperature of the thermoplastic binding material to a temperature below the melting temperature. To manufacture the press felt, an untreated press felt, which contains the nonwoven layer and the thermoplastic binding agent is first produced, the thermoplastic binding agent being distributed in the nonwoven layer in the form of thermoplastic adhesive fibres and/or a thermoplastic adhesive component of bicomponent fibres. The desired press felt is produced from the untreated press felt by means of the aformentioned temperature and pressure treatment using a smooth surface, thus enabling the press felt to be simultaneously thermofixed. |
| US08591791B2 |
Method of manufacturing a microtitration plate
A microtitration plate has a frame (2) made of a first stiff plastic and having a plate (4) with multiplicity of holes (2′), and a multiplicity of vessels (3) made of a second plastic suited for the PCR and/or exhibiting permeability to oxygen, which are fixedly connected to the plate (4) by directly molding them to the holes (6), which have a receiving portion (9, 10, 11) protruding from an underside (8) of the plate (4), and which are accessible from an upper surface (7) of the plate through apertures (15). |
| US08591788B2 |
Method of forming a composite structural member
A method of forming a hollow composite construction member of the type suitable for use as building material includes providing an elongated inflatable mold assembly having a longitudinal axis. The mold assembly further has a flexible, substantially tubular bladder wall defining an elongated inflatable cavity, wherein the cavity is movable between a deflated condition, an inflated condition, and a plurality of partially inflated conditions. A reinforcing fabric is positioned concentrically around the flexible bladder wall. A flexible air-impervious outer layer is positioned concentrically around the fabric, with the bladder wall and the outer layer defining an elongated annular space. The fabric is positioned within the space. An intermediate member is inserted within the elongated annular space between the reinforcing fabric and the tubular bladder. A fluid is introduced into the cavity to at least partially inflate the mold and shape the fabric. The mold assembly is bent along the longitudinal axis to a curved shape. The elongated annular space is infused with a rigidification material such that the fabric is permeated with the rigidification material. The rigidification material is hardened to form a rigid hollow composite construction member. |
| US08591786B2 |
Method for manufacturing floor panels, as well as floor panel obtained by means of such method
Method for manufacturing floor panels having a top layer having a composition based on a synthetic material. At least at two opposite sides, the floor panels have profiled edge areas that include at least coupling parts. For manufacturing the floor panels, one starts from a board-shaped material, and the floor panels are formed at least partially by way of a laser treatment of the board-shaped material. |
| US08591783B2 |
Medical devices with encapsulated visibility particles
The preparation and use of medical devices having radiopaque and echogenic materials including coated tungsten and/or tungsten carbide particles are disclosed herein. |
| US08591779B2 |
Method of manufacturing plastic containers
A method of manufacturing plastic containers by a blow molding machine, where the blow molding machine is operated such that at least two different plastic containers are output from the blow molding machine within one production cycle. |
| US08591777B2 |
Method of controlling longitudinal properties of optical fiber
A method of creating optical fiber to exhibit predetermined length-dependent characteristics (e.g., chromatic dispersion, polarization mode dispersion, cutoff wavelength, birefringence) includes the steps of: characterizing the fiber's selected characteristic(s) as a function of length; and performing a “treatment” which modifies the refractive index over the given length to adjust the defined parameter to fall within a defined tolerance window. These steps may be repeated one or more times until the measure of the parameter falls with the defined tolerance limits. The treatment process may include, for example, a low energy actinic radiation exposure, anneal, mechanical strain, DC voltage, plasma application, etc. Indeed, if the treatment process is repeated, a different technique may be used to adjust the refractive index (“different” processes include, for example, modifying the strength/time of a UV exposure, temperatures for annealing, etc.). |
| US08591773B2 |
Heterojunction nano material, negative pole piece of lithium ion battery, and lithium ion battery
The present application provides a heterojunction nano material, a negative pole piece of a lithium ion battery, and a lithium ion battery, where the heterojunction nano material includes a MoO3 nanobelt and a metal oxide in the alloy lithium intercalation mechanism coated on the surface of the MoO3 nanobelt. The negative pole piece of the lithium ion battery uses the heterojunction nano material as an active material, and the lithium ion battery using the negative pole piece of the lithium ion battery has a large reversible specific capacity and a high cycle stability. |
| US08591771B2 |
Dispersed solution of carbon nanotubes and method of preparing the same
Disclosed herein are a dispersed solution of carbon nanotubes including carbon nanotubes, an organic solvent, a spacer, and a dispersant, and a method of preparing the same. The dispersed solution of the carbon nanotubes includes both the spacer, which reduces the van der Waals force of the carbon nanotubes and prevents bundling of the carbon nanotubes, and the dispersant, which maintains the debundling and stability of the carbon nanotubes, thereby improving the dispersibility of the carbon nanotubes. The method of preparing the dispersed solution of the carbon nanotubes can easily produce a dispersed solution of carbon nanotubes without performing a separate chemical treatment. |
| US08591769B2 |
Hydrogen production with reduced carbon dioxide generation and complete capture
The present invention is a method of reducing the carbon dioxide balance from a reformer furnace flue gas to the high pressure syngas exit water gas shift reaction unit. Introducing a heated gas mixture into at least one pre-reforming chamber. The heating being provided by indirect heat exchange with one or more of an SMR furnace flue gas or an SMR furnace syngas introducing the gas mixture into a standard H2 PSA unit, wherein the gas mixture is separated into a hydrogen enriched stream and a PSA tail gas stream; introducing the PSA tail gas stream into a CPU system, wherein the PSA tail gas stream is separated into a carbon dioxide enriched stream, a hydrogen rich stream, and a residual stream, and introducing the residual stream as fuel into the reformer furnace along with natural gas. |
| US08591764B2 |
Chemical mechanical planarization composition, system, and method of use
The disclosure relates to chemical mechanical planarization (CMP) polishing compositions including proline and a fluorochemical surfactant. The wafer polishing composition may be used as a solution substantially free of abrasive particles, the composition of which can be adjusted to control Oxide Removal Rate and oxide over nitride Selectivity Ratio in Shallow Trench Isolation (STI) processing of semiconductor wafers using a fixed abrasive CMP process. In certain embodiments, the disclosure provides a working liquid for fixed abrasive CMP including proline and a fluorochemical surfactant at a pH from 9 to 11. When used in a fixed abrasive CMP system and method for STI, exemplary working liquids may yield an Oxide Removal Rate of at least 500 angstroms per minute, and an oxide over nitride Selectivity Ratio of at least 5. |
| US08591761B2 |
Apparatus including hydrofluoroether with high temperature stability and uses thereof
An apparatus is provided that includes a device and a mechanism for heat transfer that includes a provided hydrofluoroether having high temperature stability. Also provided is a method of transferring heat and a composition that includes a provided hydrofluoroether. |
| US08591756B2 |
Method of manufacturing a metallized ceramic substrate
A method of manufacturing a metallized ceramic substrate includes forming a metal layer on a ceramic substrate, and forming on the metal layer a resist having a first patterned resist opening and a second patterned resist opening for the metal layer to be exposed therefrom. A first width of the first patterned resist opening is greater than the thickness of the metal layer, and a second width of the second patterned resist opening is less than the thickness of the metal layer. A wet-etching process is conducted, to form in the first patterned resist opening a patterned metal layer opening and form in the second patterned resist opening a patterned metal layer dent. Therefore, an internal stress between the metal layer and the ceramic substrate is reduced, and the yield rate and reliability of the metallized ceramic substrate is increased. |
| US08591754B2 |
Plasma processing apparatus and plasma processing method
A tray for a dry etching apparatus includes substrate accommodation holes penetrating a thickness direction and a substrate support portion supporting an outer peripheral edge portion of a lower surface of a substrate. An upper portion includes a tray support surface supporting a lower surface of the tray, substrate placement portions on each of which a lower surface of the substrate to be placed, and a concave portion for accommodating the substrate support portion. A dc voltage applying mechanism applies a dc voltage to an electrostatic attraction electrode. A heat conduction gas supply mechanism supplies a heat conduction gas between the substrate and substrate placement portion. During carrying of the substrate, the outer peripheral edge of the lower surface of the substrate is supported by the substrate accommodation hole. During processing of the substrate, the substrate support portion is accommodated in the concave portion. |
| US08591753B2 |
Laser processing method
A laser processing method of converging a laser light into an object to be processed made of glass so as to form a modified region and etching the object along the modified region so as to form a through hole in the object comprises a browning step of discoloring at least a part of the object by browning; a laser light converging step of forming the modified region in the discolored part of the object by converging the laser light into the object after the browning step; and an etching step of etching the object after the laser light converging step so as to advance the etching selectively along the modified region and form the through hole. |
| US08591751B2 |
Very thin high coercivity film and process for making it
High Hc (>4,000 Oe) and high Hk (>1 Tesla) has been achieved in FePt films as thin as 70 Angstroms. This was accomplished by starting with a relatively thick film having the required high coercivity, coating it with a suitable material such as Ta, and then using ion beam etching to remove surface material until the desired thickness was reached. |
| US08591750B2 |
Multilayer wiring board and manufacturing method thereof
Provided is a method for manufacturing a multilayer wiring board, whereby even if the multilayer wiring board suffers warping or irregularities, thin-film patterns with great uniformity that are to be used as a mask for forming a wiring layer can be obtained in a simple way. A primer-coated metal foil 20 composed of a primer resin layer 21 and a metal layer 22 is placed on a surface of a double-face CCL 10, which is prepared by applying metal layers 12 and 13 onto the surfaces of a support base 11, and the primer-coated metal foil 20 and the double-face CCL 10 are bonded and the primer resin layer 21 is cured. A via Vb is thereafter formed from the metal layer 22 side, and a metal-plate layer 30 is formed on the resulting metal layer 22. After that, the etched down metal-plate layer 30 and the metal layer 22 are patterned, and using the patterned layers as a mask, the primer resin layer 21 is patterned. Using the patterned primer resin layer 21 as a mask, the metal layer 12 of the double-face CCL 10 and the metal-plate layer 30 are patterned to form a wiring pattern. |
| US08591746B2 |
Screening device for supplying water to an industrial installation
A screening installation includes, provided in a flume (5) conveying a fluid flowing with a total flow QE: a screening device (10) including a screen which includes at least one filter member in order to screen a fraction Q10 of the total flow, at least one first passage (31) in the flume which is adapted to allow a fraction Q31 of the total flow to pass such that QE=Q10+Q31, so long as the head loss between the upstream side and the downstream side of the screening device is less than a predetermined value, and at least one second passage (32) in the flume which is adapted to allow a fraction Q32 of the total flow to pass such that QE=Q10+Q31+Q32 when the head loss is greater than the predetermined value. |
| US08591743B2 |
Portable system for on-site iodine extraction from an aqueous solution
A portable system for extracting iodine from brine on-site is disclosed. The portable system includes a mobile platform containing a treatment unit for oxidizing iodine ions into elemental iodine, an adsorption unit capable of binding iodine, and may also have an electrolytic cell and/or a gas-liquid separator. The treatment unit and the adsorption unit may be located in the same or different portable operating devices. When transported to a field site containing natural gas wells, the natural gas wells provide a fluid stream containing natural gas and brine. The separators can separate the natural gas from the brine, and the brine is then run through the treatment unit and the adsorption unit to bind iodine present in the brine. The brine is then returned to the natural gas well. Upon saturation, the portable operating device is transported to a second location, where iodine is extracted from the adsorption unit. |
| US08591741B2 |
Thin film composite membranes incorporating carbon nanotubes
Processes for manufacturing a thin film composite membrane comprising multi-walled carbon nanotubes include contacting under interfacial polymerization conditions an organic solution comprising a polyacid halide with an aqueous solution comprising a polyamine to form a thin film composite membrane on a surface of a porous base membrane; at least one of the organic solution and the aqueous solution further including multi-walled carbon nanotubes having an outside diameter of less than about 30 nm. |
| US08591740B2 |
Method and system for biofouling control of shipboard components
A chlorine based biofouling control subsystem is utilized to facilitate shipboard water management systems such as ballast water management that employ filters. The biofouling control system can serve as a subsystem to promote antifouling and reduce the filter clogging due to biofouling, which improves the efficiency and effectiveness of the ballast water treatment management system. An antifouling agent of the biofouling control system breaks up the dense colonies of marine organisms being filtered or treated by the main water management systems. |
| US08591738B2 |
Membrane unit and membrane separation device
In a membrane separation apparatus, a cleaning effect for membrane elements by scrubbing is improved. In the membrane separation apparatus 14 including a separation membrane 5 (membrane element) dipped in treated liquid in a treatment bath 15, and air diffusing means 2 for diffusing air bubbles 6 for cleaning the separation membrane 5, an air bubbles staying plate 3 is provided between the air diffusing means 2 and the separation membrane 5. The air bubbles staying plate 3 is configured to allow air bubbles 6 diffused from the air diffusing device 2 to stay, by which air bubbles 6 gather each other to form air bubbles 6 having large diameters. By causing air bubbles having large diameters to act on the separation membrane 5, air bubbles 6 can be allowed to act whole the separation membrane 5. |
| US08591736B2 |
Water filter unit
A filter unit includes a body portion having a proximal end and a distal end. First and second engagement surfaces traverse at least part of the body portion. The first and second engagement surfaces include a first segment that extends substantially parallel with the longitudinal extent of the body portion. A second segment extends at an angle relative to the longitudinal extent of the body portion. A third segment extends at a different angle than the second segment. A laterally extending key member is disposed on the body portion between the first engagement surface and the second engagement surface. An engagement protrusion extends from the proximal end. The engagement protrusion has a first portion that includes a first radius of curvature and a second portion opposing the first portion that includes a second radius of curvature that is larger than the first radius of curvature. |
| US08591735B2 |
Drinking water purification device
A fast acting water purification system containing a source of silver ions which is suitable for use in personal or household water containers, where the non-potable water may contain halides or other materials that limit the solubility of silver in the non-potable water, with the purification agent including a source of silver ions and a compound containing a hydantoin ring increase the presence of silver ions in the non-potable water to a level sufficient to quickly kill harmful microorganisms in the non-potable water without the need to add additional biocides to the non-potable water or pretreat the non-potable water. |
| US08591734B2 |
Method of substance separation by supercritical fluid chromatography and vapor liquid separator for use therein
A method comprising liquefying a gas to thereby obtain a liquefied gas; injecting a sample into a mobile phase containing a solvent and a supercritical fluid formed from the liquefied gas; passing this mobile phase through a column so that the mobile phase containing desired substance is divided into the solvent and the gas; and separating the desired substance from the solvent, wherein when the pressure of the gas divided from the mobile phase is higher than the pressure of the gas fed for formation of the liquefied gas from gas supply device, the gas divided from the mobile phase is liquefied. Further, there is provided a vapor liquid separator for use in the method. |
| US08591731B2 |
Dual media fluid filter
A filter apparatus has a housing, an inlet port on one side of the housing and an outlet port on an opposed side of the housing. Sheet media is disposed in the housing having a first opening through the sheet media. Also dispersed in the housing is a bag media comprising an enclosed bag with a second opening into the bag. The first opening and the second opening are connected in fluid communication with each other and the sheet media is disposed before the bag media in the direction of flow through the housing so that both media are mounted inside the housing. Some fluid entering the inlet passes through both openings and through the bag media and into the outlet, and other fluid entering the inlet passes through the sheet media and then to the outlet. |
| US08591727B2 |
Pipeline crude oil in coal liquefaction
The present disclosure provides methods and systems for coal liquefaction using a pipeline crude oil. A method of obtaining a de-ashed coal extract includes exposing a coal to a pipeline crude oil to form a slurry, elevating the temperature of the slurry to facilitate liquefying the coal and liberating a volatile matter, and separating the insoluble components from the slurry to obtain a de-ashed coal extract, wherein the coal extract is suitable for downstream processing. |
| US08591725B2 |
Deposit mitigation in gasoline fractionation, quench water system and product recovery section
A method for selecting a solvent or mixture of solvents useful for mitigating deposit formation, cleaning existing deposits, and/or decreasing the rate of deposit formation is disclosed. Decreasing the rate at which deposits may form and/or increasing the rate at which deposits may be removed can dramatically improve process economics (e.g., decreasing down time as a result of deposit formation). In one aspect, embodiments disclosed herein relate to a process for dispersing foulants in a hydrocarbon stream, including the steps of: determining a nature of foulants in a hydrocarbon stream; selecting a solvent or a mixture of solvents suitable to disperse the foulants based upon the determined nature; and contacting the foulants with the selected solvent or mixture of solvents. |
| US08591719B2 |
Electrolysis cell for hydrogen peroxide production and method of use
An electrolytic cell for the production of hydrogen peroxide with faradic efficiency and a method for the production of highly pure hydrogen peroxide with high faradic efficiency are disclosed. The cell is provided with a separator of high hydraulic permeability and is equipped with an oxygen-fed gas-diffusion cathode and with an anode activated with a catalyst for oxygen evolution. The high faradic efficiency of hydrogen peroxide generation is allowed by the dilution of product hydrogen peroxide by the anolyte crossing the permeable separator, and by keeping the operating temperature at values below 50° C. |
| US08591713B2 |
Electrophoresis cassette
A pre-packaged electrophoresis cassette (1), the cassette (1) comprising a gel layer (2) and a buffer solution layer (3), the gel layer comprising a first polymer made from a monomer and a cross-linker, and being in contact with the buffer solution layer to form a gel-buffer interface (4) for receiving a sample which is to undergo electrophoresis. The gel and/or the buffer solution are such that absorption of water by the gel layer from the buffer solution layer is inhibited, thereby maintaining the performance capabilities of the electrophoresis cassette during storage. |
| US08591712B2 |
Gas sensor element and gas sensor
There is provided a gas sensor element, including a solid electrolyte layer, a pair of sensor electrodes arranged on a front side of the solid electrolyte layer, a pair of sensor leads arranged on a rear side of the solid electrolyte layer and connected to the respective sensor electrodes; and insulating layers, one of which is arranged between one of the sensor leads and the solid electrolyte layer and the other of which is arranged between the other sensor lead and the solid electrolyte layer. The sensor electrodes have rear end portions located on the insulating layers and overlapping front end portions of the sensor leads, respectively. The sensor leads are denser than the sensor electrodes and have front ends located in the same positions as or positions rear of front ends of the insulating layers, respectively. There is also provided a gas sensor with such a gas sensor element. |
| US08591710B2 |
Method and apparatus for formation of oriented magnetic films for magnetic recording media
A method of forming a layer of a magnetic material with radially oriented magnetic anisotropy, comprising sequential steps of providing a circular, annular disk-shaped substrate having an inner diameter and an outer diameter, forming a layer of a magnetic material with non-radially oriented magnetic anisotropy over at least one surface of the substrate, and re-orienting the magnetic anisotropy in a radial direction. Preferably, the re-orientation is performed magnetically and the radially oriented layer serves as a magnetically soft underlayer (SUL) of a magnetic recording medium. Also disclosed is a multi-chamber apparatus for performing the disclosed process. |
| US08591709B1 |
Sputter deposition shield assembly to reduce cathode shorting
A shield assembly for a sputter deposition chamber, the shield assembly including an outer sleeve with a gas inlet to conduct a gas through the outer sleeve and an inner sleeve disposed within the outer sleeve, the inner sleeve including gas channels on a surface mating with the outer sleeve to conduct the gas between the inner and outer sleeves. The shield assembly may further include an aperture ring adjacent to a first end of both the inner and outer sleeves, the aperture ring including a plurality of gas outlets to conduct the gas from the gas channels and an inner aperture flange extending from the plurality of gas outlets and adjacent to gas shield flange to form a gas runway for conducting the gas toward a sputter target located within the deposition chamber. |
| US08591707B2 |
Hydrogen gas generator
A hydrogen generating device comprising an anode, a cathode, a housing having an internal cavity and a perforated wall within the cavity electrically connected to the anode or the cathode and separating an end portion of the cavity from a main portion of the cavity. The device includes water in the housing extending continuously from the main portion of the cavity through the perforated wall and into the end portion of the cavity. The housing includes two ends and a perforated wall within the cavity near each end separating end portions of the cavity from a main portion of the cavity, the anode or the cathode extending through one end of the housing through one perforated wall into the main portion of the cavity, through the other perforated wall into the other end portion of the cavity and through the other end of the housing. |
| US08591704B2 |
Fluid fractionation process and apparatus
A fractionation process for producing at least two concentration fractions of a fluid including a solute, suspended or dissolved content using at least two fluidly connected evaporator units is provided. The process includes the steps of: feeding a feed fluid including a solute, suspended or dissolved content into at least a first evaporator unit; evaporating a first amount of fluid from the feed fluid in at least the first evaporator unit to produce a first concentrated fluid; feeding at least a portion of the first concentrated fluid into at least a second evaporator unit; and evaporating a second amount of fluid from the first concentrated fluid in at least the second evaporator unit to produce a second concentrated fluid. |
| US08591700B2 |
Susceptor support system
The present disclosure is directed to a susceptor support that includes a hub and a plurality of arms extending radially from the hub, where each arm has a terminal end positioned away from the hub. The susceptor support also includes a plurality of elongated rectangular tips formed at the terminal end of each arm, each tip having a length and a width, wherein the length is greater than the width. |
| US08591699B2 |
Method and system for supplying a cleaning gas into a process chamber
A method and apparatus for cleaning a process chamber are provided. In one embodiment, a process chamber is provided that includes a remote plasma source and a process chamber having at least two processing regions. Each processing region includes a substrate support assembly disposed in the processing region, a gas distribution system configured to provide gas into the processing region above the substrate support assembly, and a gas passage configured to provide gas into the processing region below the substrate support assembly. A first gas conduit is configured to flow a cleaning agent from the remote plasma source through the gas distribution assembly in each processing region while a second gas conduit is configured to divert a portion of the cleaning agent from the first gas conduit to the gas passage of each processing region. |
| US08591689B2 |
Method for selectively producing film laminates for packaging and for insulating unpackaged electronic components and functional patterns and corresponding device
A method for selectively producing film laminates for packaging and for insulating unpackaged electronic components and functional patterns and corresponding device. The method coat surface regions of functional patterns arranged on a substrate and/or of surface regions of semiconductor chips arranged on the substrate. An insulation is to be effectively adapted in its properties to different requirements of functional patterns and/or electronic components. Film regions are laminated on surface regions in such a way that the properties of the plastics material of the film regions are adapted to the function of the film. This adaptation is individual and selective. Various films are used. The method is suitable in particular for coating or packaging electronic components or active and passive devices. |
| US08591688B2 |
Functional film and method for producing the same
A method for producing a functional film, comprising the steps of: feeding a substrate continuously from a film roll, forming a coating film on the substrate, providing a laminate film on a surface of the coating film, and winding up the resultant substrate into a film roll; and loading the film roll wound up in the prior step into a vacuum film-forming apparatus, feeding the substrate provided with the laminate film continuously from the film roll, peeling off the laminate film, forming an inorganic film on the coating film on the substrate, and winding up the resultant substrate into a film roll, wherein for the laminate film, an adhesive film having an adhesive layer having a peel force of 0.01 N/25 mm or more and 0.06 N/25 mm or less against the coating film is used. |
| US08591687B2 |
Lamination station for laminating a paperboard or cardboard web
A lamination station for laminating a film to a web of paperboard includes a nip roller and a cooling roller. Between the rollers there is formed a nip which presses together the film and the web of paperboard with an interjacent molten polymer layer or adhesive layer disposed between the film and the web of paperboard. The film, the paperboard and the molten polymer lie, after the nip, in abutment against the cooling roller for a certain angle interval. The nip roller is a shoe-press type roller, either comprising a pressure bar having several hydraulically operated pressure elements, or comprising one or several rigid pressure bars. |
| US08591685B2 |
Method and apparatus for producing composite fillers
Apparatus for producing a composite filler includes at least one die and a device for moving a stack of reinforced ply strips through the die. The die has peripheral die face adapted for forming the ply strip stack into a desired cross sectional shape. The cross section of the die face may vary around the periphery of the die. |
| US08591681B2 |
Method for producing composite material mold for composite material long member
The present invention provides a method for producing a mold made of a composite material by using a prepreg material. First, a material 200 of a mold having a long two-dimensional shape and in a semi-cured state is produced from a prepreg sheet by continuous pultrusion molding. Subsequently, the semi-cured material 200 is mounted on a plurality of templates 131, 132, 133, 134, and 135 vertically provided on a base plate 120 of a molding apparatus 100, and thereby plastically deformed into a three-dimensional shape. The entire molding apparatus 100 is heated and pressurized to produce a completely-cured mold. |
| US08591678B2 |
Vacuum forming machine and method of making vacuum formed product
A vacuum forming machine includes a holder arranged to hold a decorative sheet, upper and lower boxes separated by the decorative sheet and the holder, a pressure reducer arranged to reduce pressures inside the upper and lower boxes, a first valve arranged to adjust a degree of pressure reduction inside the upper box, a second valve arranged to adjust a degree of pressure reduction inside the lower box, a heater arranged to heat the decorative sheet, a temperature information collector arranged to collect temperature information about the temperature of the decorative sheet, and a controller programmed to control opening/closing operations of the first and second valves by reference to the temperature information while the pressure reducer is operating. |
| US08591677B2 |
Utility materials incorporating a microparticle matrix formed with a setting agent
A composition, utility material, and method of making a utility material is disclosed. A composition having an improved setting time may include a plurality of microparticles mixed with a sodium silicate binder and an isocyanate setting agent, where the microparticle composition has a setting time of less than or equal to one hour. A utility material may be a wallboard that includes the composition. |
| US08591674B2 |
Making ductility-enhanced magnesium alloy sheet materials
A method of enhancing the ductility of magnesium alloy sheets containing 85% or more by weight of magnesium is described. An annealed, substantially strain free, sheet of generally uniform grain size is locally deformed in local regions to develop strained ‘islands’ of a predetermined strain embedded in a substantially strain-free matrix and then annealed. The deformed regions undergo recrystallization and grain growth while the remainder of the sheet suffers only minor change in grain size, leading to sheet with grains having a bimodal size distribution. The ductility of alloys processed in this way is significantly greater than the ductility of the unprocessed, uniform grain size alloy without compromise to the tensile strength of the alloy. |
| US08591670B2 |
Process and composition for treating metal surfaces using trivalent chromium compounds
An acidic, aqueous composition contains a trivalent chromium compound, an organo-functional silane, and a compound of a group IV-B element. The composition protects metal surfaces, preferably aluminum and aluminum alloys, against corrosion and improves their paint adhesion. The trivalent chromium compound may comprise chromium fluoride and optionally others, such as chromium nitrate. The organo-functional silane is preferably an aminopropyltriethoxy silane, and the compound of a group IV-B element is preferably fluorozirconic acid. The composition can either be dried-in-place or rinsed before a further coating layer is applied. The composition may also include at least one polymer having a plurality of both carboxylic functional groups, alone or with hydroxyl groups. A process uses the aqueous composition either with or without the organo-functional silane along with a sealing step following the application of the aqueous composition; the sealing step involves applying a sealing composition, including an organo-functional silane, to the metal surface. |
| US08591669B2 |
Method of texturing polycrystalline iron/gallium alloys and compositions thereof
The present disclosure is directed to a method of shaping a starting material of polycrystalline Fe—Ga alloy sheet of varying texture or crystal orientation. The method includes texturing the surface of the Fe—Ga alloy sheet to re-orient polycrystalline Fe—Ga crystals of the polycrystalline Fe—Ga alloy sheet to increase the uniformity of the crystal orientation of the Fe—Ga alloy sheet. The texturing step includes: initially deforming the Fe—Ga alloy sheet by hot rolling; subsequently deforming the previously hot rolled Fe—Ga alloy sheet by warm rolling; and annealing the previously warm rolled Fe—Ga alloy sheet. The method provides an alloy having a saturation magnetostriction potential greater than 60 ppm in applied fields of between 200-600 Oersted. During the annealing step H2S gas is added to introduce sulfur for promoting surface-energy-induced selective growth of {110} grain. The annealing step is performed in an atmosphere of argon gas. |
| US08591666B2 |
Method and apparatus for cleaning particle filters in exhaust gas systems of combustion engines
A method for cleaning particle filters in exhaust gas systems of combustion engines, in particular diesel engines in vehicles. In order to clean a particle filter, a noncombustible, ash-free cleaning fluid is sprayed into the particle filter at high pressure by a spray nozzle, across an area of said filter through which the exhaust gas flows during the operation of the combustion engine, in a quantity such that the interior of the particle filter is substantially completely soaked. Also provided is an apparatus for carrying out the method, which includes a container containing, under pressure, the fluid to be injected into the particle filter to be cleaned, an outlet valve, and a spray nozzle, which can be connected to the outlet valve via a hose and can be inserted into a space in the exhaust gas system situated before or after the particle filter. |
| US08591662B2 |
Methods for cleaning a semiconductor substrate
A method for cleaning a substrate is provided. The method initiates with applying an activation solution to a surface of the substrate. The activation solution and the surface of the substrate are contacted with a surface of a solid cleaning surface. The activation solution is absorbed into a portion of the solid cleaning element and then the substrate or the solid cleaning surface is moved relative to each other to clean the surface of the substrate. A method for cleaning the surface of the substrate with a solid cleaning element that experiences plastic deformation is also provided. Corresponding cleaning apparatuses are also provided. |
| US08591661B2 |
Low damage photoresist strip method for low-K dielectrics
Improved methods for stripping photoresist and removing etch-related residues from dielectric materials are provided. In one aspect of the invention, methods involve removing material from a dielectric layer using a hydrogen-based etch process employing a weak oxidizing agent and fluorine-containing compound. Substrate temperature is maintained at a level of about 160° C. or less, e.g., less than about 90° C. |
| US08591658B2 |
Laser probe tip fiber cap cleaning
In a method of cleaning a fiber cap of a laser probe tip, a glass fiber comprising a cap body having an internal cavity and an opening to the cavity at a proximal end is provided. A particulate collecting member is also provided. An electrical charge is applied to the particulate collecting member. A distal end of the particulate collecting member is then inserted through the opening and into the cavity of the fiber cap. Particles located within the cavity are attracted to the particulate collecting member. The attracted particles attach to the particulate collecting member. The particulate collecting member is then removed from the cavity. |
| US08591657B2 |
Substrate processing apparatus and method of manufacturing semiconductor device
Metal corrosion and substrate contamination can be suppressed, and process quality and yield can be improved. A substrate processing apparatus comprises: a process chamber; a substrate holder; a cover part closing and opening the process chamber; a substrate holder stage; a rotary mechanism rotating the substrate holder stage; a rotation shaft inserted through the cover part and connected to the substrate holder stage and the rotary mechanism so that a first gas ejection port is formed therebetween; a first gas stagnant part surrounded by the rotary mechanism, the cover part, and the rotation shaft; a second gas ejection port formed at the substrate holder stage; a second gas stagnant part formed at the rotation shaft and communicating with the process chamber via the second gas ejection port; and a flow port formed at the rotation shaft for connecting the first and second gas stagnant parts. |
| US08591656B2 |
Compound semiconductor manufacturing device, compound semiconductor manufacturing method, and jig for manufacturing compound semiconductor
When compound semiconductor layers are formed on a compound semiconductor substrate (40) by sequentially layering group III nitride semiconductor crystalline layers by metal organic chemical vapor deposition method, the compound semiconductor substrate (40) is attached inside of a reaction container with the crystal growth surface thereof facing upward, a protection member (60) having plural grooves (63) formed in a radiating manner on the side facing the crystal growth surface is attached above the compound semiconductor substrate (40), and a material gas is supplied to the inside of the reaction container through a first through hole (61) provided in the center of the protection member (60). Thereby, in the manufacture of a compound semiconductor using metal organic chemical vapor deposition method, a decrease in yield caused by adhesion of peeled-off reaction byproducts to the substrate or to the epitaxially grown film on the substrate is suppressed. |
| US08591655B2 |
Apparatus for the preparation of film
A thin film-forming apparatus, for ensuring uniform plane distribution of properties of a film formed on a substrate surface, has a gas-supply port 24a supplying a gas mixture from a gas-mixing chamber 24 to a shower head 25. The port is arranged at the peripheral portion on the bottom face of the gas-mixing chamber so that the gas mixture flows from the upper peripheral region of the head towards the center thereof. An exhaust port 32 discharging the exhaust gas generated in the film-forming chamber 3 is arranged at a position lower than the level of a stage 31 during film-formation directing the exhaust gas towards the side wall of the chamber 3 and discharging the exhaust gas through the exhaust port. The stage 31 is designed to move freely up and down to adjust the distance between the shower head 25 and substrate S. |
| US08591654B2 |
Device for manufacturing sic single crystal and method for the same
A device for manufacturing a SiC single crystal includes: a raw material gas introduction pipe; a raw material gas heat chamber having a raw material gas supply passage for heating the gas in the passage; a reaction chamber having a second sidewall, an inner surface of which contacts an outer surface of a first sidewall of the heat chamber, and having a bottom, on which a SiC single crystal substrate is arranged; and a discharge pipe in a hollow center of the raw material gas heat chamber. The supply passage is disposed between an outer surface of the discharge pipe and an inner surface of the first sidewall. The discharge pipe discharges a residual gas, which is not used for crystal growth of the SiC single crystal. |
| US08591648B2 |
Crystal growing system having multiple rotatable crucibles and using a temperature gradient method
A crystal growing system having multiple rotatable crucibles and using a temperature gradient method comprises a crystal furnace, a plurality of crucibles, a supporting device, and a temperature control device. The crystal furnace includes a furnace body, a heater, and a hearth, wherein the furnace body from outer to inner includes an outer shell, a fiber insulation layer, an insulation brick layer, and a refractory layer. The crucible supporting device includes an elevator, a plurality of crucible guiding tubes, and a plurality of tube holders each capable of supporting a crucible guiding tube, a moving device that is connected to the elevator, a motor with electrical power that is connected to the moving device, wherein there is an affixing device between each pair of guiding tube and guiding tube holder. Each crucible is located in a corresponding crucible guiding tube. The crucible supporting device is a rotatable device. The refractory layer is ⅔-⅚ of the total height of the hearth, and the heater, is located at ¼-½ of the height of the hearth. The present invention promotes doping of crystal and makes doping more uniform. |
| US08591640B1 |
Bio-renewable fast crystallizing phase change inks
A phase change ink composition suitable for ink jet printing, including printing on coated paper substrates. In embodiments, the phase change ink composition comprises both a crystalline component and an amorphous component which are derived from bio-renewable materials. The composition provides for a robust, rapid crystallization ink composition. |
| US08591638B2 |
Metal surface treatment aqueous solution and method for inhibiting whiskers on a metal surface
A tin or tin alloy plating film surface treatment aqueous solution that can reduce whiskers on the surface of a tin or tin alloy plating film, and can provide a favorable tin or tin alloy plating film using a simple method for tin or tin alloy plating films that are used on electronic components. |
| US08591636B2 |
Plating catalyst and method
Stable zero-valent metal compositions and methods of making and using these compositions are provided. Such compositions are useful as catalysts for subsequent metallization of non-conductive substrates, and are particularly useful in the manufacture of electronic devices. |
| US08591635B2 |
Fluid aeration-reduction system
A separator may include a body, an inlet portion, and an outlet conduit. The body may include a conical interior surface defining a conical cavity. The cavity may have a first outlet at a tip of the body. The inlet portion may be connected to the body and may include an outer surface, a cylindrical inner surface, and a first inlet passage extending between the outer surface and the inner surface. The inner surface may be defined by the longitudinal axis. The first inlet passage may be positioned relative to the inner surface such that a fluid flow through the first inlet passage is generally tangent to the inner surface. The outlet conduit may extend through the inlet portion and into the cavity. The outlet conduit may include a second inlet passage disposed inside of the cavity and a second outlet disposed outside of the body and the inlet portion. |
| US08591634B2 |
Method and equipment for selectively collecting process effluent
An apparatus and process for recovering a desired gas such as xenon difluoride, xenon, argon, helium or neon, from the effluent of a chemical process reactor that utilizes such gases alone or in a gas mixture or in a molecule that becomes decomposed wherein the chemical process reactor uses a sequence of different gas composition not all of which contain the desired gas and the desired gas is captured and recovered substantially only during the time the desired gas is in the effluent. |
| US08591623B2 |
Honeycomb manufacturing method using ground nut shells and honeycomb body produced thereby
A method of manufacturing a honeycomb body is disclosed having the steps of mixing inorganic source materials, a nut shell pore former, and forming aids to form a plasticized batch, wherein the nut shell pore former has a particle size distribution with 20 μm≦dp50≦70 μm, and forming the plasticized batch into the honeycomb body having a plurality of channels formed by intersecting walls. Green honeycombs and porous ceramic honeycombs produced by the method are also disclosed. |
| US08591619B2 |
Filter mounts for a portable fan and methods for mounting a filter to a portable fan
A filter frame is removably attachable to a box fan. The filter frame is adapted for receiving a standard HVAC-style filter for removing contaminants from air flow induced by the fan. In this manner, a cost-effective means for filtering a flow of air is provided for residential and commercial settings. The filter frame is adaptable to a variety of standard box fan types of different styles and dimensions. The frame is configured to accommodate standard filters, such as those readily available from retail hardware stores and home centers. |
| US08591617B2 |
Powder coating apparatus and method
A filter support casing and filter provides powder into a Bernoulli flow system. The system has an upper end and a lower end, the upper end having an opening therein. The filter support casing extends downward from the upper end. There is a filter supported within the casing. The filter support casing and the filter define an internal volume within both the filter support casing and the filter. The volume is exposed to the opening in the upper end and as later explained is flow connected into a gas stream that will carry particles and spray particles. The casing has at least two concentric elements, a first inner elements and a second outer element, that rotate with respect to each other and which slide with respect to each other. The two elements rotate about their concentric positions and slide along their lengths. The first inner element is contiguous (adjacent and/or touch and adjacent) with the filter. The first inner element encloses the filter with arms (fingers, extensions, posts, etc.) extending from a top of the first inner element to a bottom of the first inner element. The arms provide an open area between arms between the top of the first inner element and the bottom of the first inner element. |
| US08591616B2 |
Direct replacement filter with automatic pleated filter media advance
The invention is directed to a direct replacement filter having a housing with an exposure slot with a filter media storage area having unexposed folded, pleated filter media stored therein, being unexposed pleated, folded, and stacked to be compactly held within storage area. An at least one motor is coupled to a power supply and in communication with a controller. An at least movement member is coupled to an at least one support member coupled to the media. A containment area also provided where the controller signals the motor engaging the movement member which is driven such that the movement member drives the at least one support member which engages the unexposed folded pleated filter material, moving the unexposed folded pleated filter media the storage area toward the containment area and moving an exposed portion of the filter media through the at least one exposure slot toward the containment area. |
| US08591615B2 |
Dust collecting apparatus of vacuum cleaner having function of removing dust detached from filter
A dust collecting apparatus for a vacuum cleaner is provided. The dust collecting apparatus includes a centrifugal separating portion, a dust receptacle to collect dust which is separated by the centrifugal separating portion and a filter portion having a filter unit separating dust from an air current discharged from the centrifugal separating portion. The filtering portion further includes a dust removing unit to detach the filter dust caught in the filter unit, and a dust discharge member to move the filter dust to an upstream of the centrifugal separating portion. |
| US08591614B2 |
Method of manufacturing exhaust gas purifying apparatus and exhaust gas purifying apparatus
A method of manufacturing an exhaust gas purifying apparatus includes providing an exhaust gas-treating body. A holding sealing material is provided. The holding sealing material includes inorganic fibers. The holding sealing material has a first end face and a second end face each provided approximately in parallel with a width direction. The holding sealing material is wound around a periphery of the exhaust gas-treating body to form a gap between the first end face and the second end face. The exhaust gas-treating body with the holding sealing material is housed in a casing. At least one of a first electrode member and a first sensor is disposed at the gap of the holding sealing material so that at least one of the first electrode member and the first sensor is connected to the exhaust gas-treating body, passes through the holding sealing material, and penetrates the casing. |
| US08591612B2 |
Cerium oxide slurry, cerium oxide polishing slurry and method for polishing substrate using the same
The present invention provides a cerium oxide slurry, a cerium oxide polishing slurry, and a method of polishing a substrate by using the same, wherein decrease of scratches and polish at high speed can be realized by reducing the content of coarse grains by improving in the disperse state of cerium oxide particles. The invention relates to a cerium oxide slurry containing cerium oxide particles, dispersant and water, in which the ratio of weight of cerium oxide/weight of dispersant is in a range of 20 to 80 and relates a cerium oxide polishing slurry comprising the cerium oxide slurry and additives such as a water-soluble polymer. |
| US08591611B2 |
Aqueous cutting fluid and slurry
An aqueous slicing fluid comprising (A) 0.01-20 wt % of a modified silicone is combined with abrasive grains to form an aqueous slicing slurry which has advantages of dispersion stability of abrasive grains, viscosity stability, and a higher machining accuracy. |
| US08591609B2 |
Reformer with high durability
A reformer including a heating unit, a first combustor for receiving and oxidizing a heating unit fuel at a first end of the heating unit, and a second combustor for receiving and oxidizing an anode off gas at a second end of the heating unit, a reforming unit having a first reforming portion surrounding the heating unit, a second reforming portion surrounding the first reforming portion, and a flow path portion connecting the first reforming portion and the second reforming portion to provide fluid communication therebetween, and a heat resistant shield between the flow path portion and the second combustor. Here, the heat resistant shield protects the reforming unit from being distorted by thermal expansion caused by the heating unit. In addition, the flow path portion may be formed with a blade configured to further protect the connector from being distorted by thermal expansion. |
| US08591608B2 |
Gasifier ash processing subsystem
A gasifier includes a combustion zone where a gas is introduced and fuel is combusted and at least one sensor for measuring a predetermined condition in the gasifier. A grate subsystem contains the fuel and includes at least one grinding mechanism. A controller is responsive to the at least one sensor and controls the grinding mechanism by activating the grinding mechanism if the predetermined condition exists to reduce the collection of non-fuel products on the grate subsystem. |
| US08591604B2 |
Battery electrodes
A cathode includes a foil current collector including a coating containing iron disulfide on one side that covers less than 100% of the side. |
| US08591598B2 |
Method for treating morbid obesity
A method for treating morbid obesity in a body of a mammal having a gastrointestinal tract extending through a stomach and a pyloric sphincter and a wall forming the stomach and pyloric sphincter. At least one implant is formed in the wall in the vicinity of the pyloric sphincter to inhibit emptying of the stomach. |
| US08591595B2 |
Ankle-joint endoprosthesis
An endoprosthesis for replacing the ankle joint includes a lower component which is configured to be connected to the ankle bone, an upper component which is configured to be connected to the shin bone, and an intermediate part which forms a slide joint both with the lower and upper components. The intermediate part, which is wedge-shaped in sagittal section, is provided in order to compensate for anatomical or surgical irregularities. The upper component can also be wedge-shaped in frontal or sagittal section. |
| US08591594B2 |
Motion facilitating tibial components for a knee prosthesis
An orthopaedic tibial prosthesis includes a tibial baseplate sized and shaped to cover substantially all of a resected proximal tibial surface, and a tibial bearing component sized to leave a posteromedial portion of the tibial baseplate exposed when the tibial bearing component is mounted to the baseplate. The exposed posteromedial portion of the tibial baseplate includes a chamfered profile which cooperates with a correspondingly chamfered profile at a posteromedial edge of the tibial bearing component to create a substantially continuous chamfer extending from the resected tibial surface to the medial articular surface of the tibial bearing component. Advantageously, this chamfer leaves an absence of material (i.e., a relief or void) at the posteromedial edge of the tibial prosthesis, thereby enabling deep flexion of the prosthesis without impingement between the tibial prosthesis and adjacent anatomic tissues or prosthetic structures. |
| US08591592B2 |
Method of implanting partial humeral head prosthesis
A humeral prosthesis includes a stem component and a partial humeral head component. The partial humeral head component has a configuration that is similar to the curvature of the humeral head to allow the head to reconstruct the anatomy of the damaged humerus. The stem component is threaded and cannulated and engages the partial humeral head component. The stem component is configured to be inserted within the humeral diaphyseal channel. |
| US08591591B2 |
Spring base glenosphere
A reverse modular humeral implant for implantation into a humerus that includes a natural humeral shaft and a natural humeral head. The implant includes a humeral stem implantable into the natural humeral shaft, and an adapter couplable to the humeral stem, the adapter including an anchoring projection configured to be coupled to a convex bearing. |
| US08591588B2 |
Spinal fixation plate
Spinal fixation plates for maintaining adjacent vertebrae in and fixed position are provided. In an exemplary embodiment, the plate includes opposed superior and inferior portions that are angled in a direction anterior to an anterior face of a mid-portion of the plate. The plate also includes a curvature formed therein about a longitudinal axis in a sagittal plane thereof. In use, when the plate is attached to adjacent vertebrae, the angle of the superior and inferior portions and the curvature in the plate are effective to position one or more thru-bores formed in the superior and inferior portions at the anterior rims of the adjacent vertebrae. In another embodiment, a spinal fixation plate is provided that is adapted to engage and mate to a fusion cage or other vertebral implant disposed between adjacent vertebra. The present invention also provides spinal fixation kits or assemblies, and methods for implanting the same. |
| US08591581B2 |
Methods of use of cartilage implants
Methods of using cartilage implant devices are provided. The methods include locating articular cartilage having a lesion, and utilizing an implant having dimensions compatible with the lesion. The method further includes forming a cavity in the articular cartilage, subchondral bone, and cancellous bond, and engaging the implant with the cavity so that the lower face of the articular end of the implant abuts against the subchondral bone, and the stem of the implant abuts against the cancellous bone. |
| US08591578B2 |
Adjustable suture-button constructs for ligament reconstruction
An adjustable suture-button construct for ligament reconstruction. The construct is a knotless, adjustable, flexible suture loop, a first fixation device (a free or removable slotted button) and optionally a second fixation device (a fixed, non-removable button). Suture ends of the knotless suture loop provide a variable-length graft support that can be adjusted prior to, during, or after deployment of the constructs. The removable, detachable fixation device is provided with attachment feature(s) to permit assembly onto the adjustable loop. The removable, detachable fixation device is attached to the tibia end of the loop construct after the loop construct is passed through the tibial tunnel (i.e., once the loop exits the anterior tibia cortex). If a fixed, non-removable button is employed, the fixed, non-removable button is securely attached (by stitching, for example) to the graft. |
| US08591577B2 |
Capsulotomy device and method using electromagnetic induction heating
A capsulotomy device for use in an eye having a capsular bag, comprising a conductive, primary coil capable of generating magnetic field lines and a conductive, secondary coil configured to permit insertion through an incision having a diameter of 3 mm or less, and placement on the capsular bag. When the magnetic field lines are projected through the secondary coil, a current is generated within the secondary coil. |
| US08591576B2 |
Method for altering the geometry of the heart
A system (1) for altering the geometry of a heart (100), comprising an annuloplasty ring; a set of elongate annulus-papillary tension members (21, 22, 23, 24), adapted for forming a link between said ring (10) and a papillary muscle, and a first set of papillary anchors (30) for connecting each of the tension members (21, 22, 23, 24) to the papillary muscle; and where said annuloplasty ring (10) has at least one aperture (12, 13); where each of said annulus-papillary tension members (21, 22, 23, 24) are extendable through said ring (10) through said apertures (11, 12, 13), and through an atrium to an exterior side of said atrium, such that the distance of each link between the annulus and the muscles is adjustable from a position exterior to the heart while the heart is beating. |
| US08591560B2 |
Dynamic stabilization connecting member with elastic core and outer sleeve
A dynamic fixation medical implant having at least two bone anchors includes a longitudinal connecting member assembly having an elongate core and an outer sleeve. The core is of one-piece construction, elastic, and includes end portions for attachment to the bone anchors. The outer sleeve may include compression grooves. The sleeve surrounds the core and extends between the pair of bone anchors, the sleeve being compressible between the bone anchors. |
| US08591558B2 |
Bone anchoring device
A bone anchoring device has an anchoring element, a receiving portion, and a pressure element. The anchoring element includes a shank to be anchored in a bone or a vertebra and a head, the head having an exterior surface with a spherical segment-shaped portion. The shank and the head are separate parts. The receiving portion includes a first end, a second end, a longitudinal axis passing through the two ends, a bore coaxial with the longitudinal axis, and a first region adjacent to the second end for receiving a spherical segment-shaped section of the head. The pressure element exerts pressure on the head to lock the head in the receiving portion. The head has a hollow inner portion to receive a free end portion of the shank and wherein the head and the end portion are formed such that the end portion can be elastically clamped by the head. |
| US08591555B2 |
System with integral locking mechanism
A system for affixing at least two portions of bone is provided. The system has a first end cap, a second end cap, and a linking member extending between the first end cap and the second end cap. The first end cap has at least one leg configured to connect the linking member to the first end cap and configured to retain the connection. The system provides an integral locking system mechanism that does not require an additional locking element. |
| US08591549B2 |
Variable durometer lumbar-sacral implant
Medical devices for the treatment of spinal conditions are described herein. The medical device includes a main body that is adapted to be placed between the L5 vertebra and the sacrum so that the main body acts as a spacer with respect to the L5 vertebra and the sacrum to maintain distraction therebetween when the spine moves in extension. The main body is formed from a material having a gradual variation in modulus. |
| US08591546B2 |
Interspinous process implant having a thread-shaped wing and method of implantation
A spinal implant adapted to be inserted into an interspinous space between adjacent spinous processes includes a proximal section, a central section, and a distal section disposed sequentially along a longitudinal axis. The distal section has feature(s) that allow the implant to be inserted laterally into the interspinous space, such as an approximately helical groove and/or a thread-like structure. The distal tip of the implant tapers inwardly, and may be rounded. The proximal section may include an outwardly extending wing or flange. The implant may include a main body that includes the wing or flange and a spacer slidably mated to the main body through the wing or flange. |
| US08591536B2 |
Ultrasonic surgical instrument blades
An ultrasonic surgical instrument including an ultrasonically actuated blade or end effector having a treatment portion. The blade can define a central axis and at least one axis which is transverse to the central axis, wherein the transverse axis can lie within a plane which is perpendicular, or normal, to the longitudinal axis and can define a cross-section of the treatment portion. Such a cross-section can include a central portion and a step extending from the central portion, wherein the central portion can comprise a width, and wherein the step can comprise a cutting edge. In at least one embodiment, the cutting edge can be defined by first and second surfaces which define an angle therebetween. In various embodiments, the position of the cutting edge and/or the angle between the cutting edge surfaces can be selected in order to balance the blade with respect to the transverse axis. |
| US08591535B2 |
Method and apparatus for anastomosis including an anchoring sleeve
Apparatus for performing a surgical anastomosis include a tubular body having an onion portion formed near the distal end of the tubular body. The apparatus includes a sleeve having a radius sized and dimensioned to slidably receive the tubular body therein. The apparatus includes a plunger assembly sized and dimensioned to be slidably received within the central lumen of the tubular body. The plunger assembly includes a distal end configured and adapted to deploy the onion portion. |
| US08591534B2 |
Implantable repair device
An implantable prosthesis for repairing or reinforcing a tissue or muscle wall defect including a first composite structure including at least one layer of a non-absorbable material, wherein the first composite structure has a central portion sized and shaped to cover at least a portion of the tissue or muscle wall defect, and has an outer periphery. The prosthesis further includes a second structure having a reinforced central region and an outer peripheral edge, a reinforcing element positioned between the first and second structures, and having an outer periphery and a stiffness greater than that of the first and second structures, and at least one pulling element coupled to the reinforced central region of the second structure. The second structure is coupled to the first structure substantially only at their respective peripheries. |
| US08591527B2 |
Suture passer with suture capturing articulating jaw at distal end for suturing in arthroscopic surgery
A suture passer including a tubular member having a proximal end and a distal end and a central axis defined therethrough, in which the tubular member includes at least one lumen formed therein, an eyelet configured to receive a suture, a movable jaw formed on the distal end of the tubular member configured to move between an open position and a closed position, in which the movable jaw includes a plurality of portions, and an actuator configured to be received within the at least one lumen of the tubular member, in which the actuator is configured to move along the central axis of the tubular member between a first position and a second position, in which, in the first position, the movable jaw is in the closed position, and in which, in the second position, the movable jaw is in the open position. |
| US08591526B2 |
Endosurgery suturing device
A suturing device includes an elongated sheath and a suturing assembly. The elongated sheath has a working end for insertion through a working channel in an endoscope and has an inner passage. The suturing assembly includes an elongated flexible base member, a first suturing arm and a second suturing arm. The suturing arms each have a proximal end interconnected with the elongated base member and an opposite distal end. A needle receiver is disposed at the distal end of each suturing arm. The suturing arms are movable between an open position wherein the distal ends are spaced apart by a first distance and a closed position wherein the distal ends are spaced apart by a second distance less than the first distance. |
| US08591523B2 |
Mid-point lock suture cutter
A surgical suture cutter that has a “wishbone” configuration and is provided with a locking mechanism having a mid-point lock that allows two operating handles to be locked in a predetermined position at which point the cutting jaw is held flush with the shaft but suture between the jaws of the cutter is allowed to slide without being cut. The locking mechanism is formed of first and second members provided with a first engagement element (for example, a hook) and a second engagement element (for example, a notch), to allow secure engagement of the first engagement element when the suture cutter instrument is in the mid-point locked position. |
| US08591520B2 |
Apparatus for inserting catheters or endoscopic devices into a body cavity
An apparatus for inserting an elongated device into a body cavity has a valve having a longitudinal axis. The valve is provided with a housing having a cup-shaped recess and a base, a first channel section provided in said base, a plunger having an end face, said plunger being at least with its end face inserted into and displacable within the cup-shaped recess, a second channel section provided in the plunger, and a hollow cylindrical elastic seal arranged within the cup-shaped recess between said base and said end face, said seal having an outer face and an inner face defining there between a cross section of the seal, a third channel section provided in the seal and surrounded by the inner face. The third channel section forms together with the first channel section and the second channel section a central channel, said central channel extending and being continuous along said longitudinal axis. Said seal is provided with a change in said cross section in a region along said longitudinal axis. |
| US08591508B2 |
Electrosurgical plenum
An electrosurgical probe having a plenum which prevents contact of the active electrode with tissue, while simultaneously allowing a fluid/interfacing agents to contact the active electrode. |
| US08591506B2 |
Vessel sealing system
An electrosurgical system is disclosed. The electrosurgical system includes an electrosurgical generator adapted to supply electrosurgical energy to tissue. The electrosurgical generator includes impedance sensing circuitry which measures impedance of tissue, a microprocessor configured to determine whether a tissue reaction has occurred as a function of a minimum impedance value and a predetermined rise in impedance, wherein tissue reaction corresponds to a boiling point of tissue fluid, and an electrosurgical instrument including at least one active electrode adapted to apply electrosurgical energy to tissue. |
| US08591504B2 |
Systems and methods for regulating pressure levels in an inter-expansion-element space of a cryoablation system
A cryoablation catheter assembly includes a catheter having a coolant outtake region and receives a guide tube and a coolant transfer tube. The coolant transfer tube receives and transfers coolant from a coolant source to an expansion element coupled to a distal portion of the catheter. The expansion element includes an outer layer disposed over an inner layer such that the expansion element defines an inter-expansion-element space between the inner layer and the outer layer and an intra-expansion-element space within the inner layer. The intra-expansion-element space is in fluid communication with the coolant outtake region and the coolant transfer tube. The inter-expansion-element space is in fluid communication with a fluid pathway that transfers fluids to a fluid-drawing source. A pressure regulation system is disposed along the fluid pathway and passively regulates the pressure in the inter-expansion-element space using at least one check valve. |
| US08591501B2 |
Coherent fiber bundle system and method for ophthalmic intervention
Systems and processes are described relating to laser-based ophthalmic intervention technologies, and, more specifically, to techniques for creating lesions on an eye using a modular system featuring one or more coherent fiber bundles configured to deliver laser energy to the eye from a separate housing wherein a laser source is located. The subject technology may be utilized to not only separate a patient from certain portions of the hardware, but also to facilitate patterned lesion creation using mobile devices such as LIO and laser endoprobe devices. |
| US08591499B2 |
Tools and methods for programming an implantable valve
Integrated tools for noninvasively reading and adjusting an implantable, magnetically adjustable valve, and methods of use are disclosed. The tools include magnetic or electronic reading of the valve, and magnetic or electromagnetic adjustment of the valve. In use, the tools are positioned above or in contact with the patient's skin, in proximity to the valve. |
| US08591496B2 |
Respiratory secretion retention device, system and method
An apparatus, system, and method for managing respiratory secretions and fluids in sections of artificial airways. In an embodiment of the invention, a respiratory secretion retention (RSR) device configured to fluidly connect to an artificial airway can be provided. The device can include a housing that defines a passageway for the flow of respiratory gases with at least two chambers coupled to the housing. The chambers are configured to retain exhaled respiratory particulate and liquid. The respiratory secretion retention device further includes a patient port coupled to the housing that is in fluid communication with the artificial airway and a repositionable barrier configured to isolate at least one of the two chambers from the passageway. In another embodiment, a secretion removal assembly can connect to a respiratory secretion retention device; the secretion removal assembly includes a connector configured for connecting to a port of the respiratory secretion retention device and a spike coupled to the connector. |
| US08591488B2 |
Devices and methods for treating accidental bowel leakage
Described here are body liners and methods for treating accidental bowel leakage using one or more body liners. The body liners may be formed from one or more liner layers and in some instances may comprise one or more adhesive regions to connect the body liners to the skin of a wearer. The body liners may be configured to absorb fluid, and may selectively distribute fluid relative to the body liner. |
| US08591484B2 |
Lacrimal punctum measurement and occlusion
Methods and apparatus for treatment of dry eyes by providing a single apparatus for measuring the diameter of the lacrimal punctum and, based on the measured punctal diameter, inserting therein an appropriately sized punctum plug. |
| US08591482B2 |
Huber needle safety apparatus
The invention presented is a needle system to access a subcutaneous port primarily for the administration of chemotherapy, designed to protect the health care worker from inadvertent needle injury by isolation of the needle tip within base and tower components. A rotating collar is designed to keep the needle immobile until access of the port is desired when it can be rotated to align a cut out with a corresponding cut out of the tower that houses the needle for advancement of the needle downward into the port. On retraction, the collar can be rotated, locking the needle back into a retracted position within the tower. |
| US08591481B2 |
Microfabricated instruments and methods to treat recurrent corneal erosion
In one embodiment, the present invention provides a device and method for treating recurrent corneal erosion. In one embodiment, the method includes the steps of contacting an epithelium layer of a cornea with an array of glass micro-rods including a plurality of sharp features having a length that penetrates a Bowman's layer of the eye, wherein the plurality of sharp features of the array of glass micro-rods produces a plurality of punctures in the Bowman's layer of the eye that are of micro-scale or less. In another embodiment, the present invention provides a method and device for drug delivery. In one embodiment, the device includes an array of glass micro-rods, wherein at least one glass micro-rod of the array of glass micro-rods includes a sharp feature opposite a base of the array of glass micro-rods, wherein the sharp feature includes a treated surface for delivering a chemical compound to the eye. |
| US08591480B2 |
Surgical cannula
A surgical cannula and method may be constructed in disposable or reusable forms, and may have at least one outwardly extending projection or rib along an outer surface of a tubular shaft. Such a rib, or ribs, may also extend along an outer surface of a cannula tip. A bore in the tubular shaft may have a substantially circular cross-sectional shape, or alternatively in embodiments with outwardly extending ribs may be non-circular and include at least one lobe extending outward into at least one outwardly projecting rib. Some embodiments also include apertures having peripheries that are at least partly configured to form cutting edges. |
| US08591479B2 |
Gravity-fed sterile eyewash station with float valve flow regulator
A gravity-fed, emergency eyewash station includes a flow regulator in the feed line between the solution bag and the dispensing nozzle to maintain a constant flow rate throughout the entire activation time frame. The flow regulator uses a float valve to variably open and close an orifice that feeds the dispensing nozzle. Solution enters the flow regulator from an orifice at the top and leaves from an opening at the bottom. Solution flowing into and out of the regulator quickly reaches an equilibrium state, resulting in a constant flow rate for the entire activation time frame. |
| US08591473B2 |
Manually retracted safety needle with rigid wing structure
A manually retracted safety needle device is provided having a rigid wing structure to stabilize the safety needle against the body of a patient. The safety needle device includes an elongate housing having a hub movably mounted therein. A tissue penetrating needle extends distally from the hub and a fluid conveying tube extends proximally from the hub. The rigid wing structure extends substantially along the length of the elongate member and, in one embodiment, includes wings extending transversely to a longitudinal axis of the elongate member. The safety needle is also provided with various finger gripping structures to facilitate manipulation of the safety needle device relative to the patient. |
| US08591471B1 |
Secure self adhering IV catheter assembly
A catheter assembly having a catheter with a longitudinal body having a transverse attachable detachable fastening member thereunder comprising a pliable polymeric element having a top side and a bottom side with the top side having a longitudinal groove fixedly attached to the catheter's longitudinal body with the bottom side having an adhesive layer covered by a peelably removable cover so that when removed the catheter assembly can be adhesively attached to a recipient's skin and when desirous of removal can be peelably removed from said recipient's skin. |
| US08591470B2 |
Piston seal for single incision surgery
A surgical portal apparatus for use during a minimally invasive procedure includes a housing and a portal member extending distally from the housing. The housing and portal member combination defines a longitudinal axis. The portal member is sized to be positioned within tissue and has an opening at the distal end. The apparatus also has a pliable seal and a plurality of concentrically arranged piston members, disposed within the housing. The pistons are engageable with the pliable seal and are adapted for moving relative to the housing to control the diameter of a passage through the inner portion of the seal in response to the insertion of a surgical object. |
| US08591467B2 |
Vascular access assembly and safety device
A plurality of different vascular access assemblies are described which protect a clinician from accidental needle stick injury upon withdrawal of a needle from a catheter assembly. Each of the vascular access assemblies include a safety device for guarding the needle tip of the needle upon withdrawal of a needle from the catheter assembly. |
| US08591462B1 |
Assembly and system for connecting a closure to a syringe
An assembly for closing the discharge nozzle of a syringe which is pre-filled with a drug or medication. A syringe in combination with a connecting structure removably maintain and support the closure in an operative orientation, which facilitates the rotational attachment of the syringe and the closure when the closure is in mating engagement with the connecting structure. A subsequent removal of the syringe and connected closure from the container or other type of connecting structure is thereby facilitated. The need for an individual to directly handle or touch the closure during its attachment to the syringe is restricted or eliminated. The closure assembly preferably also includes a tamper evident structure which reduces the chances of tampering with the syringe in order to access its contents. |
| US08591461B2 |
Weeping balloon catheter
Balloon catheters, and methods of treatment therewith, are provided including an inflatable first balloon at least partially enclosed by an expandable second balloon that has holes. The annular space between the first balloon and the second balloon is configured to promote delivery of the fluid evenly through holes in the second balloon to avoid problems of underloading and/or overloading. Preferably, the annular space is in communication with the holes, and the annular space is configured to receive and then to release and distribute the fluid via the holes in a substantially uniform manner such that even amounts of fluid are released in the distal and proximal holes. The first balloon may have various configurations including being tapered relative to the second balloon. The second balloon may also be tapered accordingly. The device may also include raised portions disposed in the annular space and configured to define channels having various configurations. |
| US08591459B2 |
Use of biomarkers and therapeutic agents with surgical devices
Biomarkers are collected and used to determine biological propensities of a patient, to determine the efficacy of medical devices, to select and administer therapeutic agents, to select medical devices, to make adjustments to medical devices, and/or to adjust surgical techniques. An apparatus includes a port to draw a biological fluid (e.g., a mist) from a surgical site. The apparatus includes a sensor having a cantilevered beam. The beam includes substances selected to attract certain biomarkers as the fluid is communicated across the beam. The same apparatus or another apparatus is used to administer a therapeutic agent based at least in part on collected biomarker data. The therapeutic agent delivery apparatus may include a device that is also used to create a wound at a surgical site. For instance, a harmonic surgical instrument may be used to both collect biomarkers and administer a therapeutic agent (e.g., gene therapy using sonoporation). |
| US08591455B2 |
Systems and methods for customizing delivery of sensor data
Systems and methods for continuous measurement of an analyte in a host are provided. The system generally includes a continuous analyte sensor configured to continuously measure a concentration of analyte in a host and a sensor electronics module physically connected to the continuous analyte sensor during sensor use, wherein the sensor electronics module is further configured to directly wirelessly communicate displayable sensor information to a plurality of different types of display devices. |
| US08591453B2 |
Dual pump arthroscopic irrigation/aspiration system with outflow control
A dual pump irrigation/aspiration pump system capable of operating in a plurality of different modes suitable for a variety of different endoscopic surgical procedures. The system monitors actual or calculated intra-articular pressure and adjusts flow to maintain surgeon requested pressure at the surgical site while controlling outflow. The irrigation/aspiration pump system has an inflow pump and tubing dedicated to communicating fluid to the surgical work site and an outflow pump and tubing dedicated to removing fluid from the work site at a controlled rate. The system further has different size inflow and outflow pumps and tubing cassettes, means for altering the outflow fluid flow rate to accommodate a surgical tool and a means for declogging the surgical tool in the event of blockage. In a preferred embodiment a pressure control system provides inferred pressure information representative of the pressure at the work site. |
| US08591452B2 |
Systems and methods for treating obesity and type 2 diabetes
The present invention provides systems and methods for treating and/or controlling obesity and type II diabetes. In one aspect of the invention, a device for treating obesity includes a flow restrictor and an anchor coupled to the flow restrictor. The flow restrictor is movable between a first or collapsed configuration sized and shaped for endoscopic advancement through the patient's esophagus and into a distal region of the stomach and a second or operative configuration sized and shaped for inhibiting a flow of chyme from the stomach to the pyloric sphincter. It is believed that this will cause the prolongation of satiety, and result in fewer meals being eaten and/or smaller meals being ingested. The anchor is movable between a first or collapsed configuration sized and shaped for advancement through the esophagus, stomach and pyloric sphincter and into the proximal region of the duodenum and a second or operative configuration sized and shaped to inhibit proximal movement of the anchor through the pyloric sphincter. |
| US08591447B2 |
Wound and bandage protection system and method
Wound/bandage protectors configured as a wrap, a sock/mitten, or a bandage, which may be made out of stretchable material. The wrap may have one or more fastening straps as well as possibly a first catch fastening surface. The sock/mitten may have a fastening strap and a sheath. The wrap, the sock/mitten, and the bandages may have apertures and aperture covers. In addition, the bandages may have diamond or triangular gauze configurations. |
| US08591445B2 |
Sacroiliac belt and composite structure
A sacroiliac belt with a non-elastic inner belt to wrap around the user's hips and an elastic outer belt to wrap from the back to opposite sides of the inner belt. Non-cinchable hook and loop fastener construction is used to secure the inner and outer belts in position. The inner belt includes an inside elastomeric foam layer with open-cell frictional gripping surface, a non-elastic outside layer of loop material, and a hook tab for engaging the loop material to close the belt. The inner belt may be established with a non-elastic composite foam-fabric structure comprising a bi-laminate of the foam and elastic fabric, and a strip of loop material secured lengthwise onto the fabric side of the bi-laminate. The outer belt includes an elastic strip and hook tabs for connecting to the strip of loop material. The non-elastic composite foam-fabric may be used in other orthopedic braces and supports. |
| US08591443B2 |
Elbow orthosis
An orthosis for stretching tissue around a joint of a patient between first and second relatively pivotable body portions. The orthosis includes a first arm member affixable to the first body portion and including a first extension member extending therefrom. A second arm member affixable to the second body portion is also included and has a second extension member having an arcuate shape extending therefrom. A third arm member including a third extension member having an arcuate shape extending therefrom is interposed between the first and second arm members. The third arm member is operatively connected to the first and second arm members, such that the first and third arm members travel along an arcuate path defined by the second extension member when the third arm member is moved from a first position to a second position relative to the second arm member. Furthermore, the first arm member can slide along the third extension member as the third arm member is moved from the first position to the second position relative to the second arm member. |
| US08591442B2 |
Shoulder orthorsis
A shoulder orthosis is utilized to effect relative movement between bones in a body of a patient. The orthosis includes a base section which is connected with a trunk of a patient's body, an upper arm section which is connected with an upper portion of an arm of the patient, and a lower arm section which is connected with a lower portion of the arm of a patient. An interconnection between the base section and upper arm section of the orthosis is disposed beneath an axilla between the trunk and arm of the patient. A main drive assembly is operable to rotate the lower arm section of the orthosis relative to the upper arm section of the orthosis to pivot a humerus bone in the upper arm of the patient relative to a scapula bone in a shoulder of the patient. A secondary drive assembly is operable to move the lower arm section and upper arm section relative to the base section of the orthosis to move the upper arm of the patient into alignment with the shoulder of the patient. |
| US08591439B1 |
Extended term patient resuscitation/ventilation system
An extended term resuscitation system includes a plurality of inflatable cuffs adapted to extend around separate portions of the anatomy of a patient (i.e. the chest, abdomen and legs) for enhancing the circulation when inflated/deflated periodically. A primary low-pressure-high-volume air compressor is in fluid communication with each of the cuffs through individual air handlers. The air handlers are formed with an inflation and a deflation diaphragm valve which, under the control of an electronic timer and a pneumatic circuit, connect the respective cuff to the output of the compressor for inflation or to the atmosphere for deflation. A secondary air compressor provides air under suitable pressure to the pneumatic circuit for the control of the diaphragm valves. As an option the operator may change the cyclical rate and cuff pressure. A ventilator provides oxygen to the patient in selected volumes or on demand. |
| US08591437B2 |
Advanced handable skin care device and operating method thereof
An apparatus for maintaining and supplying stable power to a skin care device comprising a DC-DC converting unit (20) for escalating the voltages from a charged battery power source (1), a skin-stimulating unit (50) with a supersonic element or an ion-inducing element, a switch unit (30) having a main switch (SW1) and various functional switches, an LCD displayer (40) for indicating various operating modes, a CPU (2) for controlling each component, a main switch initiating unit having a function when the main switch (SW1) is turned on, the CPS is activated by a switching signal inputted to an analogue input port from said CPU, the first switch unit (31) is activated by the CPU through an analogue output port, then the FET (D4) is switched to supply battery power to the DC-DC-converting unit (20), and a function of the PWM control signal, which prolongs the switching-on stage for gradually increasing the voltage up to the operating voltage during the step-up stage, and inversely shortens the switching-off stage for gradually decreasing the operating voltage during the step-down stage. A strength-adjusting switch (SW3) for controlling the strength of output voltage of the DC-DC converting unit (20), and a mode switch (SW2) for operating various modes of supersonic vibrations controlled by each vibrating frequency. An LED displayer being equipped with a minimum number of connecting pins for indicating various operating modes. Each LED is independently activated to turn on and off according to each signal of the input-output terminal from a controlling unit of the CPU. |
| US08591435B2 |
Methods and devices for biopsy and collection of soft tissue
A biopsy device may include a housing and a disposable biopsy assembly releasably received in the housing. The disposable biopsy assembly may include a cutter coaxially disposed with respect to a needle, and a plurality of gears may be engaged when the disposable biopsy sample is inserted in the housing. A tissue sample holder may be disposed within housing. |
| US08591430B2 |
Adherent device for respiratory monitoring
A respiratory monitoring system is provided. A measuring system is provided that includes, (i) an adherent device configured to be coupled to a patient, the adherent device including a plurality of sensors that monitor respiratory status, at least one of the sensors configured to monitor the patient's respiration, and (ii) a wireless communication device coupled to the plurality of sensors and configured to transfer patient data directly or indirectly from the plurality of sensors to a remote monitoring system. A remote monitoring system is coupled to the wireless communication device. |
| US08591429B2 |
Physiological parameter estimation using phase-locked loop
A method and device for physiological parameter estimation, such as heart rate estimation, use a phase-locked loop to dynamically track a dominant frequency of an acoustic signal within a frequency band for the physiological parameter and estimate the physiological parameter using the dominant frequency. Because the phase-locked loop starts searching for the current dominant frequency near the most recently identified dominant frequency, the method and device rapidly incorporate slow changes in the dominant frequency that likely reflect real changes in the monitored physiological parameter while being slow to incorporate rapid changes in the dominant frequency that are likely caused by large noise. The hysteresis in phase-locked loop tracking allows the method and device to avoid physiological parameter estimation error induced by short-term large noise and quickly reacquire the dominant frequency once short-term large noise abates. |
| US08591428B2 |
Method and apparatus for measuring blood volume
A method of measuring a blood volume, includes: reading individual specific information of a patient; estimating oxygen metabolism relating to a cardiac output of the patient; and acquiring the cardiac output based on the estimated oxygen metabolism. |
| US08591420B2 |
Ultrasound imaging apparatus and method for acquiring ultrasound image
An ultrasound imaging apparatus capable of easily displaying a three-dimensional image included in a region of interest (ROI). A display controller causes a display to display a tomographic image, and further causes the display to display a first marker indicating a three-dimensional scan range and a second marker indicating a range to generate three-dimensional image data, a range subjected to rendering, to be superimposed on a tomographic image. The second marker is rotatable on the tomographic image in accordance with an instruction by an operator. A transceiver causes an ultrasound probe to scan the three-dimensional scan range specified based on the first marker. An image processor executes rendering on, of data acquired in the scan, data included in the range specified based on the second marker, thereby generating three-dimensional image data. |
| US08591418B2 |
Methods and apparatus for ultrasound imaging
Actual ultrasound attenuation in tissue is used to calculate gain compensation profiles which are used to create a uniform image. Axial, lateral, elevation gain profiles are used to correct the attenuation and ultrasound variation in each direction. In addition, automatic activation of the automatic gain compensation is described. |
| US08591413B2 |
Echogram detection of skin conditions
Technologies adapted for using acoustic pulses to diagnose skin conditions are disclosed. A series of acoustic pulses may be directed at a skin through the speaker of a device. Acoustic reflections may be received at a microphone. The reflections may be sampled and stored as echogram data. The echogram may be analyzed to identify potential skin conditions. |
| US08591408B2 |
Light source power based on predetermined sensed condition
A medical instrument having a lighting system for illumination a target area, the system comprising a light source and associated power controller, the system being configured to move from a first illumination mode to a second illumination mode based on a sensed or determined changed condition, such as predetermined temperature and/or change in a scene or brightness signal, or lack of change, from an image sensor that may be associated with the instrument. |
| US08591407B2 |
Endoscopic vision system
The present invention relates to an endoscopic visioning system and related method for both forward and backward viewing of a body lumen. According to an embodiment, the system includes an endoscope, a vision head including a light source and a vision chip on both a proximal and a distal side of the vision head, and an extension arm for moving the vision head away from and back toward the endoscope. Alternatively, the light source and vision chip may be contained in a distal end of the endoscope. In such an alternative embodiment, the vision head is a parabolic mirror mounted on the extension arm for reflecting images, for example, from behind the distal end of the endoscope to the vision chip in the distal end of the endoscope to permit, for example, a retrograde view of the surgical site entrance. |
| US08591403B2 |
Wireless power supply system, capsulated endoscope, and capsulated endoscopic system
In a wireless power supply system including a power feeding system equipped with a transmission antenna for wirelessly transmitting an electric power from a power source, and a receiver antenna formed by winding a receiver coil around an outer periphery of a substantially bar-like core member for receiving the transmitted electric power, the length of the core member of the receiver antenna is more than 10 times longer than the diameter of the core member. |
| US08591402B2 |
Endoscope hood
An endoscope hood includes: an opening portion which is placed on a far side with respect to a leading end surface of an insertion part of an endoscope, wherein an opening is formed on the opening portion in a direction substantially orthogonal to an axial direction of the insertion part; and a flexible hood part configured to cover a portion other than the opening, on the far side with respect to the leading end surface of the insertion part, wherein gas inside of the hood part is sucked from a gas suction port of the insertion part, the opening is adsorbed onto a region to be measured, and the hood part is deformed so as to be closely adhered to the region to be measured within a range of the opening and a probe, to thereby fix the probe to the region to be measured in a state where the probe is set therealong. |
| US08591400B2 |
Medical instrument
A medical instrument, includes: an insertion section having a treatment instrument projection port and an active bending section at a position on the insertion section's proximal end portion side of the treatment instrument projection port; a joystick by which an operation of the active bending section is inputted; a driving section for driving the active bending section; and a control section for controlling the joystick and the driving section, and the control section having an active bending section which performs a control in one control mode selected from a plurality of different control modes. |
| US08591398B2 |
Telescopic tilting device
A telescopic tilting device 12 comprises a telescopic arm 14 which is extendable and retractable along an arcuate path 16. Preferably, the telescopic arm 14 includes two arcuate members 22, 24 which are telescopically slidable relative to each other. More preferably, the device further comprises a drive unit 20 having a flexible belt 43 for moving the telescopic arm 14. There is also provided an endoscope holding device 10 which has such a telescopic tilting device 12. |
| US08591393B2 |
Catheter pump
A heart pump is provided that comprises an elongate catheter body, an impeller disposed at the distal end of the elongate catheter body, and one or more bearings positioned between the catheter body and the impeller. A fluid supply line for delivering infusant into the catheter is provided. A fluid return line for transporting infusant out of the catheter is also provided. A pump assembly for regulating the infusant flow along the fluid supply line and fluid return line is provided as part of an infusion system. |
| US08591386B2 |
Exercise apparatus with cable replacement assembly
A connection assembly is provided for connecting a user-coupled link to a resistance-bearing cable in exercise apparatus. An inner collar is provided in an axial gap between an outer collar and a barrel trappingly engaging the cable. A removal method is provided facilitating low cost component replacement. |
| US08591385B2 |
Rehabilitation exercising equipment that can extend a user's legs
Rehabilitation exercising equipment includes a main frame, a seat unit mounted on the main frame, a first geared member rotatably mounted on the main frame, a second geared member rotatably mounted on the main frame, a connecting mechanism mounted between the first geared member and the second geared member to connect the first geared member and the second geared member, and two pivot mechanisms connected with the first geared member and the second geared member. Thus, when the two pivot mechanisms are driven by the user's feet, the two pivot mechanisms are pivoted forward and backward relative to the main frame in two opposite directions by connection of the connecting mechanism so as to exercise or rehabilitate the user's legs, thereby achieving an exercising or rehabilitating function. |
| US08591383B1 |
Cheerleader support system
A vertically oriented shaft has a vertically oriented central axis. A lower plate has a configuration with an upper surface integrally formed with the lower end of the shaft. An upper plate has a geometric configuration having a lower surface integrally formed with the upper end of the shaft and having an upper surface. A base plate has a center located on the central axis of the shaft. The base plate has an upper surface in facing contact with and separably coupled to the lower surface of the lower plate. |
| US08591376B1 |
Planetary gear train of automatic transmission for vehicle
A planetary gear train may include an input shaft; an output shaft; a first compound planetary gear set having first and second planetary gear sets, a second compound planetary gear set having third and fourth planetary gear sets to change the rotation speeds input from the first compound planetary gear set and the rotation speed of the input shaft input through one variable input path into eleven forward speeds and one reverse speed and to finally output the eleven forward speeds and the one reverse speed; eight rotation paths having two rotation elements connected to each other or one rotation element among the rotation elements of the first and second compound planetary gear sets; and seven friction members including four clutches interposed between the rotation paths or between a selected rotation path and the input shaft, and three brakes variably connecting a selected rotation path to a transmission housing. |
| US08591375B2 |
Clutch device
A clutch device is used in combination with a differential device. The clutch device is comprised of: a clutch housed in and rotatable with the differential device and axially movable from a disengaged state into an engaged state; a plunger slidably fit on the differential device and being axially movable from a first position where the plunger does not force the clutch to a second position where the plunger forces the clutch into the engaged state; an anti-rotated solenoid configured to drive the plunger; and a retainer supported by the differential device and in contact with both the plunger at the first position and the solenoid, whereby the plunger is barred from going beyond the first position and the solenoid is axially positioned in place. |
| US08591371B2 |
Planetary gear mechanism for a wind power plant
A planetary gear mechanism for a wind power plant includes a sun gear, an internal gear and a planetary carrier with planetary gears supported by radial and axial slide bearings. The radial slide bearings include a sleeve made of a slide bearing material and attached as an inner ring to a planetary gear shaft or mounted as an outer ring in a bore in a planetary gear. An outer bearing ring cooperating with the inner ring is formed by the bore in the planetary gear, or an inner bearing ring cooperating with the outer ring is formed by the planetary gear shaft. A slide bearing material of a first bearing element of the axial slide bearings is applied between a planetary carrier cheek and an end side of a planetary gear. The end side of the planetary gear or the planetary carrier cheek forms a corresponding cooperating second bearing element. |
| US08591369B2 |
Asynchronous boost assist system for a motor vehicle
An asynchronous boost assist system for a motor vehicle includes a first electric motor, a second electric motor positioned opposite the first electric motor and a differential gear system operatively connected to the first and second electric motors. The differential gear system includes a first differential gear set and a second differential gear set. The first differential gear set is operatively connected to the first and second electric motors and the second differential gear set is configured and disposed to operatively connect to first and second vehicle wheels. A controller is operatively connected to each of the first and second electric motors. The controller selectively independently controls an operational speed of each of the first and second electric motors to selectively provide an acceleration boost through the second differential gear set. |
| US08591368B2 |
Drive system for a wind turbine
A drive system has a gear unit with planetary gear stage with a planetary gear carrier. A first shaft associated with the gear unit has a coupling flange connectable to the shaft of a working machine or a rotor and is supported by the planetary gear carrier. The gear unit and a motor/generator unit connected to a second shaft of the gear unit are enclosed by a gearbox. The motor/generator unit additionally includes a rotor connected to a hollow rotor shaft with a rotation lock. An electrically isolating, detachable flange connection is disposed between the rotor shaft and the second shaft, with the gear-side end of the detachable flange connection connected to a hollow gear shaft. A gearbox stub which concentrically encloses a gear-side end section of the gear shaft is disposed between gear unit and motor or generator unit and forms a bearing seat for the second shaft. |
| US08591365B2 |
Transmission hydraulic control system having an accumulator
A hydraulic control system for actuating at least one torque transmitting device in a transmission includes a sump, a pump in communication with the sump, and an accumulator. A first control device and a second control device control the communication of hydraulic fluid between the pump, the accumulator, and the torque transmitting device. |
| US08591363B2 |
Transmission and traction motor module using the same
Provided is a transmission of an e-bike motor, the transmission including a plurality of planetary gears meshed with a sun gear transmitting a power of a rotation shaft of a motor, a ring gear including a gear member meshed with an inner circumferential surface of the planetary gears and a clutch member formed at the other end of the gear member to shift a direction of power in response to backward and forward rotations, where the gear member and the clutch member are individual parts, and a connection unit connecting the gear member and the clutch member lest the gear member and the clutch member idle relative to an axial direction, wherein the plurality of planetary gears and the gear member of ring gear are provided in helical gears. |
| US08591361B2 |
Vehicle drive device
A vehicle drive device includes an input coupled to an internal combustion engine; an output coupled to wheels; first and second rotary electric machines; a differential including at least three rotary elements; a control; and an engagement device. The control determines, when engine stop conditions are established while the engagement device is drivably connected, the engine is operating, and the output member is rotating, whether rotation of the first electric machine when stop conditions are established is opposite to rotation of the first electric machine when rotation of the engine stops; executes torque control where the first electric machine outputs torque to reduce the rotational speed of the engine when the stop establishing rotational direction is opposite to the subject rotational direction; and issues a command to release the drivable connection when the rotational speed of the first electric machine falls within a rotational speed range that includes zero. |
| US08591360B2 |
Vehicle power transmission device and control system for power transmission
A power transmission apparatus for a vehicle which includes a first and a second planetary gear set to transmit power to a driven wheel. A ring gear of the first planetary gear set is coupled to the driven wheel. A carrier of the first planetary gear set is coupled to a ring gear of the second planetary gear set. A carrier and a sun gear of the second planetary gear set are so linked as to have signs of power which are opposite each other. A sign of speed of the ring gear of the second planetary gear set is reversed under the condition that the a sign of speed of a motor-generator is fixed, thereby reversing the sign of speed of the carrier of the first planetary gear set, which eliminate the circulation of power between the sun gear and the carrier of the first planetary gear set. |
| US08591358B2 |
Belt tensioner
The aim of the invention is to improve a belt tensioner for a belt drive of an internal combustion engine, having a central bearing device which serves to define a pivot axis for the belt tensioning arm, and having a bearing sleeve which is connected to the tensioning arm, wherein the bearing device extends through the bearing sleeve and the bearing sleeve is mounted in a friction-damping manner by means of a plain bearing arrangement, so as to be pivotable about the bearing device, with said improvement being such that a good function of the belt tensioner is maintained despite a simplification of the design and a reduction in differently designed parts. Said problem is solved by means of a generic belt tensioner for a belt drive of an internal combustion engine, in which the plain bearing arrangement has at least two opposite sliding faces which have the same material. |
| US08591356B2 |
Baseball strike zone detection radar
Systems and methods are provided for facilitating baseball strike zone detection. In accordance with one aspect of the present disclosure, a method includes transmitting radar pulses by a phased-array of transmitting antennas in a radar beam pattern, detecting reflected radar pulses of the transmitted radar pulses at multiple receiving antennas, calculating multiple positions of a projectile based on detecting the reflected radar pulses, determining whether an incursion through a three-dimensional strike zone characterized by batter-specific settings has occurred based on the multiple positions, and providing an indication of the incursion determination for presentation to a user. |
| US08591352B2 |
Golf club head
A golf club head comprises: a hollow structure having an insertion-opening in the outer surface of the golf club head; a quick-release lid of the insertion-opening; a tubular part disposed in a hollow of the hollow structure and having a bottomed hole with which the insertion-opening communicates; and a gravity point adjuster. The gravity point adjuster comprises: a heavy-weight member having a specific gravity and a length L2; a light-weight member having a specific gravity less than that of the heavy-weight member and a length L1 more than the length L2; and an elastic member having a specific gravity less than that of the heavy-weight member, and an elastic modulus lower than those of the heavy-weight member and light-weight member. The heavy-weight member, light-weight member and elastic member are inserted in the bottomed hole by the use of the insertion-opening so that their relative positions relative to the bottomed hole can be changed easily by the golfer himself or herself. |
| US08591351B2 |
Hollow golf club head having crown stress reducing feature
A hollow golf club head incorporating a stress reducing feature including a crown located stress reducing feature. The location and size of the crown stress reducing feature, and their relationship to one another and other club head engineering variables, play a significant role in selectively increasing deflection of the face. |
| US08591346B2 |
Gravity slide ride
A rotating hub ride configured to position passenger vehicles at different vehicle radii relative to the hub's axis of rotation. The ride includes curved support arms extending outward from the hub, with a first end coupled to the hub at a lower height than a second end of the arm. A vehicle is attached, via a mounting assembly, to each curved support arm to slide radially inward and outward on the arm in response to forces applied to the vehicle due to rotation of the hub, e.g., at two or more hub rotation rates. The arm or track defines a travel path for radial movement of the vehicle. When hub rotation is halted, the vehicle slides inward on the track to a load position corresponding to a minimum vehicle radius. At increasing hub speeds, the vehicle slides outward to position the vehicle in any of a number of vehicle radii. |
| US08591341B2 |
User to user game referrals
A method is disclosed in a gaming and media system for quickly and easily creating and sending mail communications including pre-populated, or preformed, messages. Upon receipt of a communication, a recipient may also quickly and easily download a game discussed in the message. |
| US08591333B2 |
Game controller with receptor duplicating control functions
A video game controller for a video game and a receptor assembly may include a controller core unit including a housing formed with a top, bottom and opposite sides, at least the top having a plurality of control buttons thereon; and a base portion provided with a first connector; a receptor having a shape substantially similar to a component appearing in the video game. The receptor may be a gun-shaped sub-unit with a barrel portion and a gripper portion with an open slot adapted to receive the core unit. |
| US08591332B1 |
Video game video editor
A video editor for a video game is discussed. The video editor manipulates information of video game play to provide videos of game play and in some embodiments scoring of videos. |
| US08591329B2 |
Methods and apparatuses for constructing interactive video games by use of video clip
The invention provides a method for processing a frame-recording based video clip without the need of modifying the video clip and/or directly inserting any form of signals into the video clip. The method comprises the steps of: browsing the video clip frame by frame by a video editing software; importing a grid layer into the video editing software such that the grid layer is browsed synchronously with each frame of the video clip; analyzing movement of a character and/or an object in the video clip by the grid layer; generating a series of game data to record the movement; storing the series of game data in a game unit after the generation of the game data; and connecting a game input to the game unit to activate the game, wherein the game unit receives input data from the game input when the video clip is played and synchronously compares the input data with the game data to determine whether they matches with each other. The invention also provides an apparatus for constructing an interactive video game by use of a frame-recording based video clip. |
| US08591328B2 |
Mechanical-based control of video reels in a game machine
In some example embodiments, a method includes executing a wagering game that generates instructions for control of a number of mechanical reels. The method also includes converting the instructions for controlling the number of mechanical reels into identifiers of video sequences stored in machine-readable media. The video sequences comprising a display representative of a stop result of the mechanical reels. The method includes retrieving the video sequences from the machine-readable media. The method includes displaying the video sequences on displays for video reels of a wagering game machine. |
| US08591315B2 |
Environmental effects for near win events
An establishment can coordinate devices (e.g., lights, speakers, displays) to enhance a game playing environment based on events detected in a network of wagering game machines. A system can be implemented that determines an environmental effect based on an event of a wagering game (e.g., a near win event), regardless of the particular wagering game developer/manufacturer. The system can determine the environmental effect to be created for an event at the wagering game machine, at a server, etc. A request for the environmental effect is then supplied to the process and/or machine that causes the devices to create the environmental effect. |
| US08591314B2 |
Gaming system and method providing a server that determines a reel set for an initial game play and reel sets for subsequent game plays
A user playing a user device wagers a wager amount on a play of a game. A server determines a first reel set for the current play, an outcome for the current play, and a second reel set for the next play of that game on which the user wagers that same wager amount. The server communicates first reel set data, second reel set data, and outcome data to the user device. The user device spins and stops the first reel set in accordance with the determined outcome. When the user wagers that same wager amount on another play of that game, the user device displays that play of that game using the second reel set, and the server determines a third reel set for the next play of that game on which the user wagers that same wager amount and communicates third reel set data to the user device. |
| US08591310B2 |
Gaming device with wild activation symbols and wild termination symbols
A gaming device having a wild activation symbol is displayed on a set of reels or set of cards within a display device. The processor causes other symbols or cards to become wild within the display device when the wild termination symbol is displayed. When the wild activation symbol is displayed, the present invention may also provide a wild termination symbol on the set of reels or the set of cards within a display device. The processor may then stop symbols or cards from becoming wild based on the position of the wild termination symbol. |
| US08591302B2 |
Systems and methods for communication
The present invention relates to a method for using a toy for communicating with a client terminal. The method comprises encoding at least one interacting information as at least one flickering control instruction and using a toy element having a light emitting unit for emitting light according to the at least one flickering control instruction, thereby transmitting the interacting information to a client terminal. The client terminal is configured for capturing the emitted light using an image capturing device and decoding the at least one interacting information therefrom. |
| US08591300B2 |
Thermal management cabinet for electronic equipment
A thermal management cabinet for electronic equipment such as servers, having an opening in the top and bottom of the cabinet. The cabinet extends between a raised access floor of a building carrying cooled air and a drop ceiling for venting heated air. The bottom opening of the cabinet is alignable with an opening in the access floor such that cool air can pass into the cabinet and can flow through the electronic component storage area to the top opening, which is alignable with an opening in the drop ceiling. The cabinet interior is separated into temperature zones comprising at least a cold zone supplied with air from the access floor and a hot zone for venting through the top opening. At least one baffle creates the temperature zones such that air is directed to flow from the cold zone through the electronic component storage area to the hot zone. |
| US08591299B2 |
Windshield de-icing duct system
An air duct system may employ an HVAC case having an exit air duct and a return air duct, a windshield with an interior surface, an approximately vertical duct, and a horizontal duct. Ducts mount to the windshield and each define an interior passageway with the interior surface of the windshield and a second, return air, passageway. The interior passageway may receive air from the exit air duct and the second passageway may return air to the return air duct. End chambers of each duct reverse air direction 180 degrees. Air of each interior passageway may warm an adjacent area of the windshield that forms part of each interior passageway and a windshield wiper. The first air duct interior passageway may warm a windshield area coincident with a maximum non-park wiper position and the second air duct interior passageway may warm a windshield area coincident with a wiper park position. |
| US08591298B1 |
Poultry wing deboning apparatus and method
An apparatus and method for deboning a poultry wing including multiple stations. The poultry wing is cut and then placed with bones extending through a plate for engagement by a subsequent rotary disboner. The mechanism includes a convey or with the plates secured thereto and motor and controls for moving the conveyor and plates and rotary deboner. |
| US08591292B2 |
Ceiling grinder
A ceiling grinder comprising a drive unit, a grinding wheel, which can be set in rotation by means of the drive unit, a grinding head housing, which receives the grinding wheel and has an opening allowing the grinding wheel access to the surface to be ground and a holding element for holding the grinder. The ceiling grinder also has means for producing a negative pressure within the grinding head housing, by which the ceiling grinder is held on the surface to be ground, wherein the means for producing the negative pressure comprise lamellar elements, which rotate about the axis of the grinding wheel during the grinding operation of the ceiling grinder and thereby cause within the grinding head housing an air flow that induces a static negative pressure. |
| US08591291B2 |
Apparatus and grinding block for the treatment of an edge or a cutting edge
A grinding apparatus includes at least two oppositely arranged series of surfaces in slanting relative orientation and alternately overlapping each other, forming this way a groove into which an edge or cutting edge is insertable for polishing by the surfaces. The surfaces of each series of surfaces are arranged in a common plane forming a side in a respective block, the blocks arranged in a holder by which each block is spring biased towards the opposite block, the blocks operated in reciprocating movement transversely to the longitudinal direction of the edge/cutting edge while the surfaces contact opposite sides of the edge/cutting edge under spring action. A grinding block utilized in the grinding apparatus includes a series of individual surfaces arranged in a common plane forming one side of a block divided into sections, which are separated through intermediate recesses into which corresponding sections of an oppositely positioned block intermesh in a toothed engagement while forming a groove between the surfaces. |
| US08591290B2 |
Cutting head and cutting nozzle for a liquid/abrasive jet cutting arrangement
A nozzle for a high pressure cutting arrangement is disclosed. The cutting arrangement comprises a liquid stream and a slurry stream, the slurry comprising abrasive particles suspended in a fluid, with both fluids being supplied into the nozzle under pressure. The nozzle has a combining chamber, having an entry region arranged to receive the liquid stream and the slurry stream, such that the pressure in the entry region is determined by the pressure in the liquid stream. The pressure in the entry region acts on the pressure in the slurry stream to regulate the pressure in the slurry stream. |
| US08591289B2 |
Multi-spindle chemical mechanical planarization tool
An apparatus for chemical mechanical planarization includes a spindle assembly structure and at least one substrate carrier, which make a linear lateral movement relative to each other while abrasive surfaces of a plurality of cylindrical spindles in the spindle assembly structure contact, and rotate against, at least one substrate mounted on the at least one substrate carrier. The direction of the linear lateral movement is within the plane that tangentially contacts the plurality of cylindrical spindles, and can be orthogonal to the axes of rotation of the plurality of cylindrical spindles. |
| US08591288B2 |
Method and device for mechanically processing diamond
Method and device for processing a surface (5) of a diamond (1) with a mechanical part (3) which is moved in relation to the surface (5) of the diamond (1), whereby unbound diamond grains (2) are provided in between the mechanical part (3) and the surface (5) of the diamond (1), whereby the mechanical part (3) subjects the diamond grains (2) to a rolling motion over the surface (5) of the diamond (1), such that the diamond grains (2) move in relation to the mechanical part (3) and the surface (5) of the diamond (1), whereby the mechanical part (3) makes a mechanical contact with the surface (5) of the diamond (1) via the diamond grains (2), whereby this mechanical contact represents a contact length (8) over which the diamond grains (2) roll on the surface (5) of the diamond (1), mainly according to the direction of the relative motion of the mechanical part (3) in relation to the surface (5) of the diamond (1) and, whereby the diamond grains (2), with the support of the mechanical part (3), press themselves in the surface (5) of the diamond (1) while rolling, as a result of which microscopic fissures (6) are created in the latter surface (5) which then gradually crumbles off. |
| US08591285B2 |
Ultrasonic trimming apparatus
An ultrasonic trimming apparatus is composed of an articulated robot, a cutting apparatus, and a grindstone. The cutting apparatus is composed of an ultrasonic oscillator supported by the end portion of the robot, a cutter blade which is supported by the ultrasonic oscillator, and a workpiece securing portion which secures a workpiece. The grindstone is disposed within the movable range of the cutter blade driven by the robot and is placed in a position at which the cutter blade can pressure contact the cutter blade. The cutter blade is ultrasonically vibrated by the ultrasonic oscillator and is ground while being pressed against the grindstone by means of the articulated robot. The ultrasonic trimming apparatus efficiently cuts a sheet material composed of soft material such as plastic, fabric, or rubber, a composite material, or a material containing glass fiber even when the material has a three-dimensional shape. |
| US08591284B2 |
Toy with housing having movable components
The present invention relates to a toy or toy playset that includes a housing with a movable door and a movable platform. In one embodiment, the door is placed proximate to an opening in the housing and can be moved between a lowered position and a raised position. In one embodiment, the platform is movably mounted to the housing and is movable about an axis. The door and the platform are configured to be moved at the same time. In one implementation, the platform can be moved as the door moves from its lowered position to its raised position. |
| US08591281B2 |
Climbing vibration-driven robot
An apparatus includes a housing, a rotational motor situated within the housing, a vibrating mechanism, and a plurality of appendages each having an appendage base proximal to the housing and an appendage tip distal from the housing. One or more of the appendages are adapted to cause the apparatus to move across a surface in a forward direction generally defined by a longitudinal offset between the appendage base and the appendage tip, and the appendages include two or more appendages disposed such that the appendage tips of the two or more appendages are adapted to contact opposing surfaces to produce a net force in a direction generally defined by a longitudinal offset between the appendage base and the appendage tip of the two or more appendages as the vibrating mechanism causes the apparatus to vibrate. The net force can allow the apparatus to climb when the opposing surfaces are inclined. |
| US08591280B2 |
Organic light emitting display apparatus and method of manufacturing organic light emitting display apparatus
An organic light emitting display (OLED) apparatus and a method of manufacturing the same, the OLED apparatus including: a substrate; an active layer formed on the substrate; a gate electrode insulated from the active layer; source and drain electrodes insulated from the gate electrode and electrically connected to the active layer; a pixel defining layer formed on the source and drain electrodes, having an aperture to expose one of the source and drain electrodes; an intermediate layer formed in the aperture and comprising an organic light emitting layer; and a facing electrode which is formed on the intermediate layer. One of the source and drain electrodes has an extension that operates as a pixel electrode. The aperture exposes the extended portion. The intermediate layer is formed on the extended portion. |
| US08591274B2 |
Inflatable stand up paddleboard
An inflatable stand up paddleboard having a top surface for supporting a user and a bottom surface for residing on water. The inflatable stand up paddleboard being characterized as having a front end and back end and a longitudinal axis passing between the front and back ends. The inflatable stand up paddleboard is configured to receive at least one beam for stiffening the inflatable stand up paddleboard positioned substantially parallel to the longitudinal axis. |
| US08591269B2 |
Shielding terminal clamp
A shielding terminal clamp having a first limb, a second limb and a yoke having a base part, with an elastic element disposed between the first limb and second such that a pressure force is exerted on a pressure piece movably supported between first and second guide pieces of the first and second limbs, respectively, first and second ends of the elastic element being respectively disposed on the base part and the pressure piece such that the pressure force acts in the direction of an open end of the yoke opposite the base part, with a closing device, which is displaceable disposed on the yoke such that a movement in a direction extending orthogonally to the pressure force, with which the closing device and the yoke move toward one another, causes a shielding bus clamping of between the open end of the yoke and the closing device. |
| US08591263B2 |
Connector for connecting cable and terminal of same
A low profile flat printed circuit connector has a plurality of terminals supported along a support bar. The terminals are spaced apart from each other and extend lengthwise in a connector housing. The terminals have body portions that engage the support bar and body portions that extend forwardly thereof. Contact portions are joined to the body portions and extend rearwardly and terminate in free ends so that they form a series of cantilevered contacts. |
| US08591262B2 |
Substrate inductive devices and methods
Methods and apparatus for providing a low-cost and high-precision inductive device. In one embodiment, the inductive device comprises a substrate based inductive device which utilizes inserted conductive pins in combination with plated substrates which replace windings disposed around a magnetically permeable core. In some variations this is accomplished without a header disposed between adjacent substrates while alternative variations utilize a header. In another embodiment, the substrate inductive devices are incorporated into integrated connector modules. Methods of manufacturing and utilizing the aforementioned substrate based inductive devices and integrated connector modules are also disclosed. |
| US08591254B1 |
Compression connector for cables
A connector for cables has a plurality of components including a first connector structure, a second connector structure, and a conductive pin. The components cooperate to engage an end of a cable. |
| US08591253B1 |
Cable compression connectors
Cable compression connectors have a plurality of components including a first connector structure, a second connector structure, and a conductive pin. The components cooperate to engage an end of a cable. |
| US08591247B2 |
Electrical connector assembly with improved latch mechanism
A plug connector comprises a plug housing (11) having a front base portion (112) extending along a mating direction and a rear linking portion (114), a contact (12) received in the base portion, a cover (13) assembled to the linking portion, and a cable (14) electrically connected with the contact. The base portion defines a front face (1120), a pair of protrusions (1121) on an upper and a lower sides thereof, and a pair of receiving slots (1123), each protrusion defining a receiving channel (1122) extending along a transverse direction, each receiving slot extending from the front surface along the mating direction to a corresponding receiving channel. |
| US08591242B2 |
Floating battery contact module for a power tool
A battery contact module for use in a power tool including a housing (12) and a battery (30) insertable into the housing. The battery contact module (28) includes a contact block (32) movably connected to the housing (12) and a pair of opposing terminals (34) attached to the contact block (32) and configured to contact the battery (30). Thus, the contact block (32) moves relative to the housing (12) to maintain constant electrical contact pressure between each of the terminals (34) and the battery (30). The contact block (32) including locating posts (52) that loosely engage receptacle (22) on the housing (12) to allow for movement or float of the contact module in the housing. |
| US08591236B2 |
Interactive medical training system and method
A method for training a user in a medical procedure utilizes an interactive computer system with a virtual representation of at least one organ and at least one instrument. The representation of surface area parts of the virtual organ to be treated are covered with a graphical identification marker. The computer system includes a table stored in memory comprising situations arising within the medical procedure predefined through positions of the instrument(s), positions of the organ(s), the logical sequence of steps to be executed within the medical procedure, different aspect values for the graphical identification markers and assessment values for the situation. Upon interaction of the user with the organ and the instrument, graphical identification markers change their aspect according to the stored value in the table for the predefined situation and the corresponding assessment value is stored in a history log table within the computer system. |
| US08591235B1 |
Handwriting glove apparatus
Embodiments of the disclosed technology comprise a glove apparatus for teaching handwriting skills. The glove apparatus has a glove with a holder for a writing implement permanently attached to the glove. This holder grips the outer surface of a writing implement. The outer surface of the holder is attached to the glove at the thumb, pointer and middle fingers such that when the glove is put on the hand, the hand is in the proper position to learn handwriting skills. Finally a writing implement can be placed into the holder for writing and can be taken out of the holder when needed. |
| US08591230B2 |
Interproximal non-surgical caries treatment device and method
The device includes a shim component constructed for use in the non-surgical treatment of interproximal carious dental lesions. A plunger may be provided for driving substances through a tube-like channel or bore in the shim component, or an electromagnetic energy-transmissive material may fill the channel, in either case for delivering to the site of the lesion a medium that is effective for directly or indirectly killing, or biologically damaging, the carious bacteria. |
| US08591227B2 |
Mouthpiece that adjusts to user arch sizes and seals from oxygen exposure
A mouthpiece that adjusts manually to accommodate a broad range of different size sets of upper and lower teeth in the mouth and yet seals the treatment area from oxygen exposure. The mouthpiece includes light emitting diodes and heat generating resistors all arranged in an array. A series of parallel texture bands are provides to guide and direct the light from the LEDs to diffuse generally evenly onto teeth to be treated. The seal arises from an inner surface of the mouthpiece titling inwardly so that a seal bead seals in the vicinity of the gum above the teeth to be treated. |
| US08591211B2 |
Glass repairer
A glass repairer of the present invention includes a support base for fixation, a fluid-receiving tube, a pressing rod, and a rubber head for injecting repairing fluid. The fluid-receiving tube is disposed on the support base. The rubber head is fixed to an end of the pressing rod and is able to squeeze the repairing fluid in the fluid-receiving tube outward. Thereby, replenishing repairing fluid and cleaning become easier. Also, the present invention is able to be utilized repeatedly. |
| US08591209B2 |
Pump for a vehicle brake system having a valve
The invention relates to a pump having a valve through which a fluid can optionally flow. The valve is embodied by a cavity for displaceably guiding a spherical blocking body, and a valve seat that is spatially adapted to the spherical shape of the blocking body. A free space protruding radially outwards from the spherical body is located downstream, directly behind the valve seat, for temporarily receiving the fluid which flows through the valve seat. |
| US08591207B2 |
Pump with side inlet valve for improved functioning in an inverted container
A pump for use in an inverted dispenser is disclosed herein. In one embodiment, the liquid pump includes a fluid chamber that has a top portion when in the inverted position and at least one side wall located below the top portion. A liquid intake port extends through the at least one side wall and allows fluid to flow into the fluid chamber. The pump also includes a check valve to prevent fluid from flowing out of the fluid chamber through the fluid intake port that is located in the at least one side wall. Actuation of the liquid pump in a first direction causes fluid to enter the fluid chamber through the fluid intake port and actuation of the liquid pump in a second direction causes liquid to exit the fluid chamber trough the fluid chamber outlet and out of a dispensing outlet. In one embodiment, the check valve is an elastomeric valve. The elastomeric valve may include a top portion to seal of an inlet opening in the top of an existing pump to convert the pump into a pump having an inlet opening below the top of the pump. In another embodiment, the fluid piston in the liquid pump is the check valve that seals off the intake opening from the fluid chamber when the fluid piston is moved past the inlet opening. |
| US08591204B2 |
Turbo-molecular pump
A turbo-molecular pump includes a base 3; a rotor 4 rotatably supported thereon; a stator 400 disposed around the rotor 4; and a tubular casing 2 configured to accommodate the stator 400. The stator 400 includes multiple stages of stator blades 43 and spacers 48 alternately stacked one upon another on a flange surface 31 of the base 3. At least one of the spacers 48 is provided with a circular ring part 483 continuously formed thereof covering the outer circumferential surface of other spacers 48 inside the casing 2. |
| US08591200B2 |
Hydraulically controlled reciprocating pump system
A system for pressurizing a working fluid includes a cylinder having an outlet through which the working fluid is exhausted at a discharge pressure, a plunger translatably disposed within the cylinder, and a hydraulic system. The plunger has a first piston coupled thereto, a second piston disposed opposite the first piston, wherein the second piston is driven to reciprocate, and a variable-volume chamber disposed between the first and second pistons. The hydraulic system is operable to adjust the volume of hydraulic fluid within the variable-volume chamber, whereby the discharge pressure is maintained substantially at a predetermined level. |
| US08591194B2 |
Steam turbine rotor blade assembly
The present invention is a steam turbine rotor blade assembly including: an airfoil; a shroud provided at a tip of the airfoil; a blade root (dovetail) projecting toward a radially internal circumferential side of a turbine rotor and fitted to a root attachment provided on an outer circumferential portion of the turbine rotor; a platform provided between the airfoil and the blade root; a pin provided between the blade root and the root attachment; a bore formed between respective surfaces of the shrouds facing each other and included in the respective adjacent rotor blades; and a bar-like member provided in the bore. |
| US08591193B2 |
Airfoil shape for a compressor blade
An article of manufacture having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in TABLE 1. X and Y are distances in inches which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z in inches. The profile sections at the Z distances are joined smoothly with one another to form a complete airfoil shape. |
| US08591187B2 |
System and method for detecting loads transmitted through a blade root of a wind turbine rotor blade
In one aspect, a system for detecting loads transmitted through a blade root of a rotor blade of a wind turbine is disclosed. The system may include a root attachment assembly configured to couple the blade root to a hub of the wind turbine. The root attachment assembly may include a barrel nut mounted within a portion of the blade root and a root bolt extending from the barrel nut. In addition, the system may include a sensor associated with the root attachment assembly. The sensor may be configured to detect loads transmitted through at least one of the barrel nut and the root bolt. |
| US08591185B2 |
Low pressure exhaust gas diffuser for a steam turbine
A diffuser is provided for an exhaust steam housing adjacent a last stage row of buckets fixed to a rotor in a steam turbine, each bucket in the last stage row of buckets having a platform portion and an airfoil portion. The diffuser includes an annular inner diffuser ring and an outer annular diffuser ring defining a flow path for steam exiting the last stage row of buckets in a substantially axial direction at a diffuser inlet and turning substantially ninety degrees to a diffuser outlet. A first portion of the inner annular ring extends in a downstream direction beyond the last stage row of buckets substantially parallel to a center axis of the rotor, the first portion having a length dimension in the downstream direction from a radial center line of the last stage row of buckets in a range of between 0.40 and about 0.70 of a center line radial length from the platform portion to a radially outer tip of any bucket in the last stage row of buckets. |
| US08591183B2 |
Extended length cutoff blower
A blower assembly including a blower housing having a side wall with a first portion extending from the initial cutoff through an angle of at least 45° or more, the first portion having a radius which is substantially constant or which increases at a relatively small rate. The side wall additionally includes a second portion, extending from the end of the first portion to the outlet, which forms a continuous curve with the first portion and has an increasing radius which is increasing at a larger rate and has a rate of increase that is also increasing with housing angle. The shape of the side wall allows a reduction in the overall size of the blower housing for a given size of impeller. |
| US08591182B2 |
Device for suspending guide blades
A device (10) for suspending gas channel elements, in particular for suspending guide blades or guide blade segments or gas channel segments, on a housing of a gas turbines is provided. The device comprises first plate-shaped elements (11, 12, 13, 14) and second plate-shaped elements (15, 16, 17), whereby the first plate-shaped elements (11, 12, 13, 14) and the second plate-shaped elements (15, 16, 17) are connected together by web-like elements (18) which extend in an essentially perpendicular manner in relation to the first and second elements and form a meandering or crenelated profile. |
| US08591180B2 |
Steam turbine nozzle assembly having flush apertures
A steam turbine nozzle assembly having a flush aperture is disclosed. In one embodiment, the steam turbine nozzle assembly includes a diaphragm assembly comprising: an inner diaphragm ring segment; an outer diaphragm ring segment; a static nozzle blade positioned between the inner diaphragm ring segment and the outer diaphragm ring segment; and a first cavity between the static nozzle blade and one of the inner diaphragm ring segment or the outer diaphragm ring segment; wherein the one of the inner diaphragm ring segment or the outer diaphragm ring segment includes a first aperture fluidly connected with the first cavity. |
| US08591178B2 |
Very low head packaged small hydro station
The water-turbine and the intake- and exit-tubes are located in a house, which is supported on stilts from the bed of the headpond. In operation, water is siphoned upwards out of the headpond through the open underside of the house. A trashrack is located in the intake-tube, above the water level of the headpond, whereby the trashrack is in air when the turbine is not running. The trashrack is horizontal. |
| US08591177B2 |
Structure of radial turbine scroll
In a radial turbine scroll, an operating gas is led to flow in the radial direction from a spiral scroll formed in a turbine casing into turbine moving blades of a turbine rotor, which is positioned on the inner side of the scroll, so as to act on the turbine moving blades, and then led to flow outside in an axial direction, thereby rotatively driving the turbine rotor, wherein the scroll 4 has a partition plate 20 a length of a certain range on a line of a tongue portion formed on the inner periphery of a gas inlet portion or has a reduced height between scroll side walls at an outlet portion of a tongue portion 21 formed on the inner periphery of a gas inlet portion of the scroll. |
| US08591174B1 |
Wind aeolipile
Described herein is essentially a high-efficiency, hybrid fluid-aeolipile. In operation, this hybrid device is placed in the stream of a moving fluid, preferably air. Energy is extracted from the fluid stream by directing a portion of the stream through and, optionally, around the device. As the fluid-flow moves through the device, it is directed into nozzles. These nozzles, which are free to pivot in a cyclical manner, employ the established phenomenon of “nozzle-effect” to accelerate the velocity of the air-flow passing through them, which is ultimately ejected from each nozzle tip, producing thrust. This thrust, amplified by nozzle-effect, drives the nozzles to pivot around a shared axis. The wind energy, thereby converted into cyclical motion, that may be used to perform useful work, is converted with greater efficiency, than is possible in conventional blade-type wind turbines. |
| US08591171B1 |
Open-flow vertical wind generator
The generator (10) includes an essentially cylindrical stator assembly (12) defining a central turbine void (14) in which a wind turbine (16) rotates to power an electrical generator (18). The wind turbine (16) includes vanes (48) having a width (52) less than 25 percent of a diameter (58) of the turbine (16). The turbine (16) defines an open void (60) between the vanes (48) for unrestricted passage of air through the wind turbine (16). Non-planar stators (34A-34H) extend between a base and an upper truss (20, 26) to strengthen the stator assembly (12) and to direct air exiting directional ducts (36A-36H) to move in a first rotational direction (42) within the turbine void (14). A plurality of geodesic truss segments (96A-96H) form the base and upper trusses (20, 26) to produce a strong, light-weight wind generator (10) that is easily assembled on-site. |
| US08591170B1 |
Directed force turbine device
A directed force turbine device utilizing forces of wind or water current flow featuring a wheel-style rotor assembly having side panels connected via a plurality of curved vanes, the rotor assembly rotates on bearings about a fixed axle shaft, the curved vanes harness the incoming current flow, which drives rotation of the rotor assembly, the vanes surround the fixed axle shaft and form an inner cavity; a stator assembly disposed in the inner cavity of the rotor assembly, the stator assembly does not rotate with the rotor assembly, the stator assembly comprises flow directors wherein entering current flow is directed in between the flow directors which functions to apply a positive force against forward moving vanes of the rotor assembly; a funnel assembly and external flow director for controlling intake of the current flow; and an exhaust port. |
| US08591169B2 |
Rotor for generating electrical power from a flow medium
A power generation system that generates power in low flow situations is disclosed. The system includes a set of vanes, wherein each vane is mounted on a corresponding mast, so as to selectively transmit energy from the flow medium to a rotor shaft or to freely deflect in the direction of flow, depending on whether the flow impinges on the vanes in an energy-producing or a non-energy-producing direction. This is achieved by mounting each vane on its mast, so that it deflects in the flow direction when the vane is subjected to non-energy-producing flow energy, and also coupling each vane to the mast of an adjacent vane, so that the vane exerts a pull force on the mast of the adjacent vane, when the vane is capturing energy-producing flow energy. |
| US08591168B2 |
Subsurface wave power generation systems and methods
A subsurface wave power generation system includes a seabed mounting plate adapted for securing to a seabed, a wing having generally opposed first and second wing surfaces extending between a first and second wing ends, the second wing end being pivotably mounted to the seabed mounting plate such that pivoting motion about a pivot axis generally parallel to the mounting plate is imparted to the wing by subsurface wave action acting on the first and second wing surfaces, and a drive arm pivotably connected to the wing to convert the pivoting motion into reciprocal motion. An electrical generator can be driven by the drive arm through a slip linkage. The slip linkage includes a first stage that converts the reciprocal motion of the drive arm into rotational motion and a second stage that selectively engages the a drive shaft of the generator drive to impart the rotational motion thereto. |
| US08591162B2 |
Personnel transfer system
A transfer device for transferring people and/or personal equipment from a first location to a second location, the transfer device being coupled to a lifting device and comprising an outer structure in the form of a cage connected to a base and defining an inner space. Seating elements are disposed on the device's base, arranged radially around its center. The device also comprises shock absorbing means situated on the sides of the outer structure facing each of the seating elements to protect passengers from frontal impacts. |
| US08591155B2 |
Transport system for heavy-duty equipment
A green transport system includes a bogie system having forwardly disposed and rearwardly disposed bogies in which the rearwardy disposed bogie includes a front bogie and a rear bogie interconnected to the front bogie by a telescopic beam assembly for selective incremental retractable extension so that the bogies are disposed in a plurality of transport modes for load bearing exceptionally high tonnage heavy-duty tracked equipment, particularly crushers without disassembly of the crusher; the exceptionally high tonnage crusher being transported as a single unit, with resultant fuel and energy conservation and greenhouse gas emission reduction, and the elimination of a pre-crushing operation. |
| US08591153B2 |
Pneumatic drilling device
The pneumatic drilling device includes: a ram provided inside a cylindrical body so that the ram can move forward and backward therein; a spindle air motor provided inside the ram; a feed air cylinder mechanism for moving the ram forward and backward; and an air supply port for supplying compressed air to the feed air cylinder mechanism and the spindle air motor through an airflow path. The airflow path includes: a first flow path for driving the spindle air motor; and a second flow path communicating with the feed air cylinder mechanism for moving the ram forward and backward. The first flow path and the second flow path are separately and independently provided in parallel. |
| US08591150B2 |
RDX plant indicator system
A method of detecting RDX in soil includes the steps of: planting a plurality of prickly sida plants in a defined area; remotely monitoring the pigmentation of the prickly sida plants using hyperspectral imaging; and identifying one or more areas within the defined area that are contaminated by RDX based on the monitored pigmentation of the prickly sida plants. |
| US08591148B2 |
Multi-rate flow control system for a detention pond
A flow control system includes a movable riser with multiple flow rate restrictors within a stationary riser that is interfaced to a drainage system. The movable riser is buoyed by float(s) attached to the movable riser. As the fluid level around the flow control system changes, the movable riser tracks the changes, thereby raising and lowering the flow rate restrictors. Since the flow rate restrictors have differing areas in the horizontal plane, an interstitial opening between the outer edge of each flow rate restrictor and the inner perimeter of the stationary riser differs. The flow rate is constant and proportional to the depth of the fluid over the interstitial opening with the least area. The flow rate remains constant until that flow rate restrictor creating the smallest interstitial opening lifts above the upper edge of the stationary riser at which time, the next flow rate restrictor determines the flow rate. |
| US08591144B1 |
Mixer and placer paving systems
A system for delivering a paving material to a point including a frame, one or more aggregate bins coupled to the frame at a front position relative to a forward direction of travel of the system. The aggregate bins configured to hold an aggregate material. |
| US08591142B2 |
Apparatus for shaping pavement
An apparatus for shaping pavement, the apparatus comprising a pavement-shaping member for receiving a flow of shapeless pavement material and generating a flow of shaped pavement material and a paving machine mount, mechanically coupled to the pavement-shaping member, for coupling the pavement-shaping member to a paving machine, the pavement-shaping member comprising a detachable forming shoe for producing the shaped pavement material. |
| US08591141B2 |
Mobile paving machine
The invention concerns a mobile paving machine for the installation of ground covering material, with a smoothing board for stripping off the ground covering material, the smoothing board being adjustable in height and the paving machine having a probing unit with a probing foot, which probes the ground level and acts on the position of the smoothing board so that the ground covering material is flush with the ground level, wherein and the probing unit has a probing foot held by a probe support, which is articulated to a support joint, and wherein a sensor or switch unit is provided, held by a switch support, and the switch support is articulated to the probe support and interacts with the sensor or switch unit on the probe support. |
| US08591139B2 |
Plural-component, composite-material highway dowel bar structure and fabrication methodology
A plural-component, composite-material highway dowel bar and an associated fabrication methodology. The dowel bar includes an elongate, solid-cylindrical, high-shear-strength core bar, preferably steel, and an elongate, fiber-reinforced plastic-resin jacket, including an elongate, pultrusion-formed, tubular sleeve, and sleeve-received, opposite-end, end-well sleeve end plugs, fully surrounding and protectively covering the core bar. |
| US08591135B2 |
File binder and document organizer
Disclosed herein is an organizer comprising a unique structural configuration to house and store both non-perforated documents and perforated documents. The organizer comprises a ring binder that is associated with an expandable compartment that is arranged peripheral to the ring binder. |
| US08591133B2 |
Automatic switch for a power circuit usable in a bottle
An automatic switch for a power circuit of a bottle container is provided. The bottle container includes a bottle body, a cover and an electronic unit for allowing an accommodating unit to be assembled between the bottle body and the cover. A liquid is received in the bottle body. A ball is disposed in a mouth at a front end of the cover, and the ball is capable of opening/closing the mouth by means of an elastic body. The elastic body has a first conductive portion and a second conductive portion. The first conductive portion is brought into electrical contact with a positive electrode (or negative electrode) of a power source of the electronic unit. The second conductive portion is located above the negative electrode (or positive electrode) of the power source of the electronic unit by a distance when the elastic body is not pressed. |
| US08591131B2 |
Hand-held dry-erase board system
A hand-held dry-erase board system for efficiently storing a writing instrument in the handle of a portable dry-erase board. The hand-held dry-erase board system includes a frame including a writable surface, a handle, wherein the handle includes an upper end and a lower end and wherein the upper end of the handle is attached to the frame and a clip, wherein the clip is attached to the handle and wherein the clip secures a marker. |
| US08591130B2 |
Leak resistant applicator pod and method
An applicator apparatus having a sealed container pod which may be opened through an actuating tab. In certain embodiments the terminal end of the open package covered by an applicator surface that may be adherently affixed to the container pod. In certain embodiments, actuating tab passes through a void defined by a suitably shaped applicator surface. Certain embodiments describe a rupturable seal permitting mixing of contents within the container pod before distribution to applicator surface. A method for applying material to a desired surface, and method of applying a therapeutic substance to a desired tissue is disclosed. |
| US08591128B2 |
Extendable mechanism
In accordance with an example embodiment of the present invention there is provided an apparatus comprising a first assembly and a second assembly, said first assembly being connected to said second assembly by and extendable mechanism, said extendable mechanism being configured to extend an input area when the first assembly is moved with respect to the second assembly from a first position to a second position. |
| US08591126B2 |
Optical signal measurement device
A device connects to a male network connector of a network conduit, and connects to a female network connector of the network conduit. The female network connector is capable of communicating with the male network connector. The device also measures outputs of the male network connector and the female network connector. |
| US08591118B2 |
Bearing device for driving wheel
A driving-wheel bearing device includes an outer race having double-row outer raceway surfaces formed on an inner periphery thereof, a hub wheel and an inner race having a wheel attachment flange at one end thereof and double-row inner raceway surfaces on an outer periphery thereof, and double-row rolling elements interposed between the outer raceway surfaces of the outer race and the inner raceway surfaces of the hub wheel and the inner race, the hub wheel having a shaft hole into which a stem section extending from an outer joint member of a constant velocity universal joint is spline-fitted by being press-fitted, in which a plate having a molybdenum coating layer or a fluorine-resin coating layer formed thereon and having a plate thickness ranging from 0.5 mm to 2 mm is interposed between opposite surfaces of a shoulder portion of the outer joint member and an crimped portion of the hub wheel. |
| US08591115B2 |
Rolling bearing device
A rolling bearing device includes: an outer ring that has outer ring raceway grooves formed on an inner peripheral surface of the outer ring and a counter bore portion that is provided on an outer side of the outer ring raceway grooves in an axial direction; an inner ring member that has inner ring raceway grooves formed on an outer peripheral surface of the inner ring member; and a plurality of rolling elements that are interposed between the outer ring raceway grooves and the inner ring raceway grooves so as to freely roll and that are in contact with the inner ring raceway grooves of the inner ring member and the outer ring raceway grooves of the outer ring at a predetermined contact angle. A lubricant reservoir portion that stores lubricant is formed at a portion in the outer ring raceway grooves adjacent to the counter bore portion. |