| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 101 | Transgenic organisms and cells and methods of producing transgenic organisms and cells | EP89313386.8 | 1989-12-20 | EP0375406A2 | 1990-06-27 | Lo, Cecilia; Richa, Jean |
Transgenic or transomic organisms and cells and methods of producing transgenic or transomic organisms and cells are disclosed. A chromosome or chromosome fragment of a donor organism is isolated and a substantial portion of the retrieved chromosome or chromosome fragment is inserted into the heritable genetic material of a recipient organism. Methods for the retrieval, manipulation, injection and subsequent insertion of large chromosome fragments into the heritable genetic material of recipient cells are disclosed. |
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| 102 | 脂質の生産のための遺伝的に改変された生物 | JP2012525904 | 2010-08-04 | JP5954544B2 | 2016-07-20 | ラング,クリスティーン; ラアブ,アンドレアス |
| 103 | Gene to code biotin synthase and use thereof | JP440487 | 1987-01-12 | JPS6344889A | 1988-02-25 | OSAWA IKURO; FUJII NOBUKO; KAMOGAWA KOICHI; IBU RUMOANU; REMI GURAKURERU; DENI SUBETSUKU; KYO TSUGUO; HAYAKAWA KAZUKO |
| PURPOSE:To produce biotin in high efficiency, by forming DNA to code gene information participating in biosynthesis reaction of biotin from desthiobiotin derived from a bacterium belonging to the genus Bacillus, capable of producing biotin. CONSTITUTION:A recombinant vector which is integrated with NDA to code gene information participating in biosynthesis reaction of biotin from destiobiotin derived from a bacterium belonging to the genus Bacillus, capable of producing biotin is formed. A bacterium which is transformed or transduced with the recombinant is cultivated in the presence of a procursor of biotin biosynthesis in a medium containing a proper carbon source to produce biotin, which is separated and purified. A recombinant vector which is integrated with DNA in the vicinity of a promoter under the control of promoter is preferable as the recombinant vector and a bacterium belonging to the genus Escherichia coli may be cited as the bacterium for transformation. | ||||||
| 104 | TRANSCRIPTION FACTOR MODULATING TERPENE BIOSYNTHESIS | EP12731757.6 | 2012-06-08 | EP2718309A1 | 2014-04-16 | SCHUURINK, Robert Cornelis; HARING, Michael Albertus; SPYROPOULOU, Eleni |
| The present invention relates to identification and isolation of zinc finger transcription factor in tomato that specifically expresses in glandular trichomes of Solanum lycopersicum cultivar Moneymaker and binds to the promoters of the genes encoding Terpene Synthase 5 (also known as Monoterpene Synthase 1) and Terpene Synthase 11 (also known as Sesquiterpene Synthase 1). The invention provides the isolated, recombinant or synthetic polynucleotides encoding the polypeptide sequences of SEQ ID NO:2 and variants and fragments thereof. The invention also provides constructs, vectors, host cells and plants genetically modified to contain the polynucleotides of the invention. The methods for producing plants with altered levels of terpenes, including transformed and mutant plants, are also provided. | ||||||
| 105 | TRANSGENIC BIOLUMINESCENT PLANTS | EP03764423.4 | 2003-07-10 | EP1534838A2 | 2005-06-01 | Hudkins, Bruce, Eric |
| Transgenic plants are created having incorporated into them a luciferase enzyme gene and a corresponding luciferin substrate gene. These genes are regulated such that for a certain amount of time after dark, these genes are expressed resulting in bioluminescence. Different luciferin/luciferase combinations may be utilized for these transgenic plants, depending on the desired wavelength and the plant species transfected. | ||||||
| 106 | Transgenic bioluminescent plants | US14496758 | 2014-09-25 | US09441236B2 | 2016-09-13 | Bruce Eric Hudkins |
| Transgenic plants, and a method for making the same, wherein genes encoding the enzyme luciferase and its corresponding substrate luciferin are incorporated into a native plant genome. Once transformed into plant cells, these genes may be regulated such that under certain endogenous or exogenous conditions, their expression in the mature plant results in bioluminescence. Different luciferin/luciferase complexes and/or mechanisms of regulation may be utilized for these transgenic plants, depending on a variety of factors such as plant species and the circumstances under which a biolmuniescent reaction is desired. Phototransformation may be utilized to vary the wavelength of light emitted from the mature plant. | ||||||
| 107 | Transgenic BioSensor | US14564144 | 2014-12-09 | US20150204849A1 | 2015-07-23 | Christopher E. Hopkins; Miluka Gunaratna |
| Systems and methods relate to transgenic organisms and their use as biosensors are described. In some embodiments, the systems and methods include a first population of transgenic organisms that includes a first constitutively expressed reporter gene, and a first transgene that includes a first inducible promoter from a response pathway gene, wherein the first inducible promoter is coupled to a first reporter gene. Other embodiments are described. | ||||||
| 108 | Transgenic biosensors | US13476790 | 2012-05-21 | US08937213B2 | 2015-01-20 | Christopher E. Hopkins; Miluka Gunaratna |
| Systems and methods relate to transgenic organisms and their use as biosensors are described. In some embodiments, the systems and methods include a first population of transgenic organisms that includes a first constitutively expressed reporter gene, and a first transgene that includes a first inducible promoter from a response pathway gene, wherein the first inducible promoter is coupled to a first reporter gene. Other embodiments are described. | ||||||
| 109 | Transgenic bioluminescent plants | US12704330 | 2010-02-11 | US07994396B2 | 2011-08-09 | Bruce Eric Hudkins |
| Transgenic plants, and a method for making the same, wherein genes encoding the enzyme luciferase and its corresponding substrate luciferin are incorporated into a native plant genome. Once transformed into plant cells, these genes may be regulated such that under certain endogenous or exogenous conditions, their expression in the mature plant results in bioluminescence. Different luciferin/luciferase complexes and/or mechanisms of regulation may be utilized for these transgenic plants, depending on a variety of factors such as plant species and the circumstances under which a bioluminescent reaction is desired. Phototransformation may be utilized to vary the wavelength of light emitted from the mature plant. | ||||||
| 110 | Transgenic bioluminescent plants | US10195283 | 2002-07-15 | US07049483B1 | 2006-05-23 | Bruce Eric Hudkins |
| Transgenic plants are created having incorporated into them a luciferase enzyme gene and a corresponding luciferin substrate gene. These genes are regulated such that for a certain amount of time after dark, these genes are expressed resulting in bioluminescence. Different luciferin/luciferase combinations may be utilized for these transgenic plants, depending on the desired wavelength and the plant species transfected. | ||||||
| 111 | Method for generating a genetically modified organism | US10736801 | 2003-12-16 | US20040143854A1 | 2004-07-22 | Bert Klebl; Anja Stadler; Rosemarie Sollner; Ekkherd Leberer; Almut Nitsche |
| A method for generating a genetically modified organism for drug screening is presented in which heterologous expression of at least one protein in caused in the organism followed by analysis of the modified gene expression pattern of the expressing organism and phenotyping by altering the expression of the compensating differentially regulated genes. Assays using the genetically modified organism are also presented. | ||||||
| 112 | GENERATION OF TRANSGENIC AVIANS | PCT/US2005/006072 | 2005-02-28 | WO2005084430A1 | 2005-09-15 | CHRISTMANN, Leandro; EBERHARDT, Dawn; HARVEY, Alex, J.; LEAVITT, Markley, C. |
The invention includes transchromosomal avians and transchromosomal avian cells and methods for the introduction of artificial chromosomes into the genome of avians and avian cells. |
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| 113 | TRANSGENIC BIOLUMINESCENT PLANTS | PCT/US2003/021531 | 2003-07-10 | WO2004006656A2 | 2004-01-22 | HUDKINS, Bruce, Eric |
Transgenic plants are created having incorporated into them a luciferase enzyme gene and a corresponding luciferin substrate gene. These genes are regulated such that for a certain amount of time after dark, these genes are expressed resulting in bioluminescence. Different luciferin/luciferase combinations may be utilized for these transgenic plants, depending on the desired wavelength and the plant species transfected. |
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| 114 | Transgenic bioluminescent plants | US13109623 | 2011-06-02 | US08853491B2 | 2014-10-07 | Bruce Eric Hudkins |
| Transgenic plants, and a method for making the same, wherein genes encoding the enzyme luciferase and its corresponding substrate luciferin are incorporated into a native plant genome. Once transformed into plant cells, these genes may be regulated such that under certain endogenous or exogenous conditions, their expression in the mature plant results in bioluminescence. Different luciferin/luciferase complexes and/or mechanisms of regulation may be utilized for these transgenic plants, depending on a variety of factors such as plant species and the circumstances under which a biolmuniescent reaction is desired. Phototransformation may be utilized to vary the wavelength of light emitted from the mature plant. | ||||||
| 115 | Tracking genetically modified organisms with RFIDs | US12043253 | 2008-03-06 | US07868768B2 | 2011-01-11 | Robert L. Angell; James R. Kraemer |
| A Genetically Modified Organism (GMO) is tracked using Radio Frequency Identification (RFID) tags. A bulk load of GMOs, which is intended for consumption by livestock only, is laced with RFID tags at or near a time of harvest. If the RFID tags appear in a product that is intended for human consumption, then the product is pulled from distribution, since it contains GMOs that are potentially harmful to humans if eaten. | ||||||
| 116 | TRANSGENIC MOSS PRODUCING TERPENOIDS | US12783952 | 2010-05-20 | US20100297722A1 | 2010-11-25 | Aldwin Macaraig Anterola; Ralph Stephen Quatrano; Pierre-Francois Perroud |
| The present invention generally relates to transgenic moss. One aspect of the invention provides a transgenic moss cell that produces or accumulates a terpenoid compound. Another aspect of the invention provides for methods of producing a terpenoid compound through culturing of the transgenic moss. | ||||||
| 117 | Tracking Genetically Modified Organisms with RFIDs | US12043253 | 2008-03-06 | US20090224916A1 | 2009-09-10 | Robert L. Angell; James R. Kraemer |
| A Genetically Modified Organism (GMO) is tracked using Radio Frequency Identification (RFID) tags. A bulk load of GMOs, which is intended for consumption by livestock only, is laced with RFID tags at or near a time of harvest. If the RFID tags appear in a product that is intended for human consumption, then the product is pulled from distribution, since it contains GMOs that are potentially harmful to humans if eaten. | ||||||
| 118 | TRANSGENIC BIOLUMINESCENT PLANTS | EP07749524.0 | 2007-01-31 | EP2066793A1 | 2009-06-10 | Hudkins, Bruce, Eric |
| Transgenic plants, and a method for making the same, wherein genes encoding the enzyme luciferase and its corresponding substrate luciferin are incorporated into a native plant genome. Once transformed into plant cells, these genes may be regulated such that under certain endogenous or exogenous conditions, their expression in the mature plant results in bioluminescence. Different Iuciferin/luciferase complexes and/or mechanisms of regulation may be utilized for these transgenic plants, depending on a variety of factors such as plant species and the circumstances under which a bio luminescent reaction is desired. Photo transformation may be utilized to vary the wavelength of light emitted from the mature plant. | ||||||
| 119 | TRANSGENIC BIOLUMINESCENT PLANTS | EP03764423 | 2003-07-10 | EP1534838A4 | 2006-05-31 | HUDKINS BRUCE ERIC |
| Transgenic plants are created having incorporated into them a luciferase enzyme gene and a corresponding luciferin substrate gene. These genes are regulated such that for a certain amount of time after dark, these genes are expressed resulting in bioluminescence. Different luciferin/luciferase combinations may be utilized for these transgenic plants, depending on the desired wavelength and the plant species transfected. | ||||||
| 120 | IN VIVO PRODUCTION OF TRANSGENIC ORGAN BY INTRODUCING THE TRANSGENE VIA LUMEN | PCT/US1993008618 | 1993-09-10 | WO1994005782A1 | 1994-03-17 | TRUSTEES OF TUFTS COLLEGE; EBERT, Karl, M. |
| The present invention features a nonhuman animal which animal has at least one organ or gland and the organ or gland has a lumen lined with epithelial cells capable of introducing secretions into the lumen in which at least one or more of the epithelial cells have a transgene which transgene is absent from the characteristic genotype of the animal and which cell is capable of expressing said transgene to form a transgenic product. The invention further features a method of imparting such a desired trait to an animal through the lumen and into the epithelial cells which epithelial cells are capable of expressing the transgene to make a transgenic product. | ||||||
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