序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
141 IMAGING COMPOUNDS FOR DETECTING OR IMAGING SENESCENT CELLS PCT/GB2024050047 2024-01-10 WO2024149992A1 2024-07-18 GORGOULIS VASSILIS G; LOUGIAKIS NIKOLAOS; MARAKOS PANAGIOTIS; POULI NICOLE; KOTSINAS ATHANASSIOS; EVANGELOU KONSTANTINOS; PETTY RUSSELL; TZORTZATOS ILIAS CHRISTOS
A compound, or a salt or solvate thereof, according to formula I as defined herein and pharmaceutical composition comprising said compound. Compounds of formula I are capable of detecting senescence. As such, these compounds are useful in methods of detecting or imaging senescent cells or extracts thereof or senescence in a subject or a biological sample taken from a subject.
142 STYRENE-MALEIC ACID COPOLYMERIZED MACROMOLECULAR REACTIVE DYE AND PREPARATION METHOD THEREFOR PCT/CN2022077054 2022-02-21 WO2023151118A1 2023-08-17 ZHANG SHUFEN; WANG FUCHUN; TANG BINGTAO; MA WEI; NIU WENBIN; WU SULI
A styrene-maleic acid copolymerized macromolecular reactive dye, and a preparation method therefor and a use thereof. The preparation method comprises the following steps: using styrene and maleic anhydride as copolymerization starting materials, after copolymerization, introducing a nitro group to the para-position of the hydrocarbon group on a benzene ring, reducing the nitro group into an amino group, diazotizing the amino group, and coupling with a coupling component, thereby obtaining a water-soluble macromolecular reactive dye. The prepared styrene-maleic acid copolymerized macromolecular reactive dye is low in price, high in color fixation rate on fibers, excellent in fastness, particularly high in light fastness, and suitable for industrial popularization.
143 FLUORESCENCE QUENCHER POLYMER CONJUGATES AND USES THEREOF PCT/US2021039813 2021-06-30 WO2022020081A1 2022-01-27 RABBANI ELAZAR; COLEMAN JACK
The invention provides chemical conjugates comprising a plurality of fluorescence quenching moieties conjugated to polymer and the use of such conjugates to quench the emission of fluorescence from emitters including macromolecular fluorescent emitters such as phycoerythrin.
144 OLIGONUCLEOTIDE-BASED PROBES FOR DETECTION OF CIRCULATING TUMOR CELL NUCLEASES PCT/US2016/029201 2016-04-25 WO2016172701A2 2016-10-27 GIANGRANDE, Paloma, H.; MCNAMARA, James, O.; DICKEY, David, D.; OZER, Howard; KRUSPE, Sven

The present invention relates to a rapid detection of circulating tumor cell (CTC)-associated nuclease activity with chemically modified nuclease substrate probes and compositions useful in detection assays.

145 ELECTROWETTING DEVICE PCT/EP2013/077504 2013-12-19 WO2014096263A1 2014-06-26 LEGUIJT, Robin; MASSARD, Romaric Mathieu; MANS, Jurrien; ADITYAPUTRA, Muhammad Arief

Electrowetting apparatus including a compound comprising a plurality of colorant moieties and a linker. The plurality of colorant moieties includes a first colorant moiety having a first net dipole and a second colorant moiety having a second net dipole, wherein the plurality of colorant moieties are linked by and disposed around the linker so that the first net dipole and the second net dipole at least partially cancel each other.

146 POLAR DYES PCT/US2006008425 2006-03-09 WO2006099050A3 2007-03-01 GALL ALEXANDER A
The present invention relates to novel polar fluorescent and quenchers dyes, and minor groove binder with enhanced polarity. The present invention further relates to methods of preparing oligonucleotide probes labeled with polar arsonate dyes under the condition of automated synthesis and method of using such probes.
147 POLAR DYES PCT/US2006/008425 2006-03-09 WO2006099050A2 2006-09-21 GALL, Alexander A.

The present invention relates to novel polar fluorescent and quenchers dyes, and minor groove binder with enhanced polarity. The present invention further relates to methods of preparing oligonucleotide probes labeled with polar arsonate dyes under the condition of automated synthesis and method of using such probes.

148 OPTICAL STORAGE MEDIA COMPRISING PENTACYCLIC XANTHYLIUM DYES PCT/EP0303945 2003-04-15 WO03098617B1 2004-04-08 MORTON COLIN; LEHMANN URS; GRIESHABER PETER; SUTTER PETER; BUDRY JEAN-LUC; SCHMIDHALTER BEAT
The invention relates to an optical recording medium comprising a substrate, a reflecting layer and a recording layer, wherein the recording layer comprises a compound of formula (I),(II),(III); wherein R1, to R13, may be hydrogen or a variety of substituents, but R1, and R11 are not simultaneously hydrogen;Y- is an inorganic, organic or organometallic anion, or a mixture thereof; Z is a proton or a metal, ammonium or phosphonium cation, or a mixture thereof; m, n and o are each independently of the others an integer from 1 to 3; and p and q are each a number from 0 to 4, the ratio of o, p and q to one another, depending on the charge of the associated sub-structures, being such that there is no excess positive or negative charge in formula (I), (II) or (III). Also claimed are the use of a xanthene perchlorate in the preparation of compounds of formula (I), (II) or (III) having organometallic anions, and the use of lactates in the application of layers of dye to grooved substrates by spin-coating.
149 COLORED THERMOPLASTIC RESIN COMPOSITIONS FOR LASER WELDING, SPECIFIC NEUTRAL ANTHRAQUINONE DYES AS COLORANTS THEREFOR, AND MOLDED PRODUCT THEREFROM PCT/US2001/048331 2001-11-13 WO02038662A1 2002-05-16
Thermoplastic resin compositions suitable for laser (11) welding are disclosed, which include a mixture of neutral anthraquinone blue dye with other red dye to absorb visible light with wavelength less than 700 nm and transmit a laser (11) beam with wavelength at 800 nm to 1200 nm and to enhance weldability.
150 METAL CHELATE AZO DYE FOR INK-JET RECORDING, INK-JET RECORDING FLUID CONTAINING THE SAME, AND METHOD OF INK-JET RECORDING PCT/JP2001/001242 2001-02-21 WO01062854A1 2001-08-30
A black dye for ink-jet recording which comprises a metal chelate azo dye whose free-acid form is represented by the general formula (1) and which combines satisfactory achromaticity with satisfactory light resistance; and a recording fluid containing the dye. (The general formula (1) shows a molecule having one or more hydrophilic groups. In the formula (1), M represents any metal; A, B, and C each represents an aromatic ring optionally having any substituent; D represents an aromatic ring optionally having any substituent other than an azo group; R1 and R2 each represents hydrogen or any substituent; m is an integer of 0 or 1; n is an integer of 0 to 3; p is an integer of 0 to 2; and q is an integer of 1 to 3; when two or more B's are present, they may be the same or different; M can have three or more coordination bonds with any part or ligand contained in the general formula (1); and a metal ion may be further coordinated, in the form of -O-M-O-, to A and B, or to two B's spaced by an azo group when there are two or more B's, or to B and C).
151 SQUARYLIUM COMPOUNDS AND OPTICAL RECORDING MEDIA MADE BY USING THE SAME PCT/JP2000/008890 2000-12-15 WO01044375A1 2001-06-21
Novel squarylium compounds having spectral characteristics, light resistance, solubility and thermal decomposition properties which are favorable for recording material of DVD-R; and optical recording media made by using the same. In particular, novel squarylium compounds represented by general formula (I); and optical recording media provided with recording layers containing the compounds.
152 トロポロン誘導体の増感色素を用いた光電変換素子 JP2014037452 2014-02-11 JP2015154069A 2015-08-24 橋本 雅司; 関口 翔也; 見附 孝一郎
【課題】光電変換効率が高い優れた光電変換素子、及び該素子を用いる太陽電池の提供
【解決手段】対向する一対の電極間に、少なくとも増感色素を半導体に担持してなる半導体層及び電荷輸送層が設けられている色素増感型光電変換素子において、前記増感色素が下記一般式[1]で表される化合物を含有することを特徴とする光電変換素子。

〔Oは酸素原子;R1〜R5は、H、ハロゲン原子、シアノ基、置換または無置換のアルキル基、アミノ基、アルケニル基、アルキニル基、アリール基、ヘテロアリール基、から選ばれる。〕
【選択図】なし
153 Optical recording medium, metal chelate compounds, and azo compounds JP2007554969 2007-01-19 JP5006801B2 2012-08-22 恵司 上野; 雅夫 今井; 浩之 佐々木; 健一 加藤; 高史 吉田; 将敬 宮里; 章 小木曽; 智之 木下; 和浩 清野; 洋二郎 熊谷; 努 石田; 英夫 臼井; 謙一 藤井; 泰三 西本; 理穂子 鈴木; 明宏 高坂; 英一 高橋; 善昭 麻生
154 Novel whitening agents for the cellulose substrate JP2009546422 2008-01-16 JP2010516907A 2010-05-20 キーケン、ローレント・デー.; コット、ケビン・リー; サドルースキー、ユージーン・スティーブン; シビク、マーク・ロバート; スタークス、レオナード・ジェイ.; トアーズ、エデュアルド; バレンティ、ドミニク・ジェイ.; バレンティ、マイケル・エー.; ベイカー、キース・ホーマー; ホン、シャオヨン・マイケル; ムーア、パトリック・デー.
【課題】 セルロース基体のための新規な白化剤を提供すること。
【解決手段】 チオフェン着色剤を含有する少なくとも1種の発色団成分及び少なくとも1種のポリマー成分を含むセルロース基体のための白化剤。 適切な発色団成分は、紫外線を照射すると、青色、赤色、紫色、又はパープル色の蛍光を発し、又は光を吸収してそれらと同じ色合いを反射する。 この白化剤は、更に、約17MPa 0.5より低いか又は等しいハンセン溶解度パラメータの分散成分値を有することを特徴とする。 本発明はまた、これらに限定されないが、液体及び/又は粉末の洗濯洗剤組成物及びすすぎ用に添加された繊維柔軟剤(RAFS)組成物を含む、洗濯ケア組成物に関する。
【選択図】 図1
155 Metal complex of squarilium compound, and optical recording medium using the same JP2008270624 2008-10-21 JP2010100669A 2010-05-06 NIIMI TATSUO; KAMEYAMA KAZUYA; HASEGAWA YOSHIMI
<P>PROBLEM TO BE SOLVED: To provide an optical recording medium using a metal complex of a squarilium compound having a highly sensitive optical response to a purple-blue laser beam, and the like. <P>SOLUTION: The optical recording medium contains the metal complex of a squarilium compound represented by formula (I), [wherein R<SP>1</SP>represents H, or the like; k represents an integer of 0 to 5; R<SP>2</SP>, R<SP>3</SP>, R<SP>4</SP>and R<SP>5</SP>each represent H, an alkyl group, or the like; X represents a group having an active hydrogen; and A represents an aryl group, or the like]. <P>COPYRIGHT: (C)2010,JPO&INPIT
156 Electronic display filter JP2005516395 2004-12-17 JP4413193B2 2010-02-10 幾夫 清水; 元晴 衣笠; 勝巳 鵜飼
157 Compound for anisotropic film, composition for anisotropic film containing the compound for anisotropic film, anisotropic film and polarizing element JP2008182402 2008-07-14 JP2010018587A 2010-01-28 NISHIMURA MASAAKI; YONEYAMA TOMIO; SANO HIDEO; HASEGAWA RYUICHI
PROBLEM TO BE SOLVED: To provide a compound for anisotropic films having high polarization characteristics by a wet film-forming process, an anisotropic film containing the compound, and a polarizing element. SOLUTION: The compound for anisotropic films is in the form of a free acid represented by formula (1) (wherein n is an integer of 1-3; B 1 is a divalent aromatic hydrocarbon group which may have a substituent or a divalent heterocyclic group which may have a substituent; D 1 is an aromatic hydrocarbon group which is substituted with at least one sulfo group or a heterocyclic group which is substituted with at least one sulfo group; and R 3 represents an alkyl group which may have a substituent). COPYRIGHT: (C)2010,JPO&INPIT
158 Optical devices JP2003502541 2002-06-03 JP4307991B2 2009-08-05 イル グヴォン カン,; マリア レオナルドヴナ ククシュキナ,; エレーナ ユリエヴナ シシュキナ,; オルガ アクマトヴナ タンビエワ,; セルグイ ワシリーヴィッチ ベルヤエフ,; グレゴリー ニコラエヴィッチ ボロツソフ,; ナタリヤ ニコラエヴナ マサノワ,; ニコライ ウラディミロヴィッチ マリモネンコ,
159 Phthalimidoyl azo dyes, processes for their preparation and their use JP2002573863 2002-01-29 JP4260483B2 2009-04-30 アルキント,アルフォンス; ヴィルヘルム,ジャン−クロード; クレマン,アントワーヌ; ラウク,ウルス
160 Composition containing mixed dyestuff based upon at least one chromophoric group of azo-type or of tri(hetero) aryl methane-type, dyeing tequenique, and mixed dyestuff JP2007282869 2007-10-31 JP2008115390A 2008-05-22 GREAVES ANDREW; DAVID HERVE; SAMAIN HENRI
<P>PROBLEM TO BE SOLVED: To provide such a composition for use in dyeing as contains a mixed dyestuff which is based upon at least one chromophoric group of an azo-type or of a tri(hetero)aryl methane-type. <P>SOLUTION: The composition for use in the dyeing contains one mixed dyestuff comprising at least two different chromophoric groups in the medium suitable for the dyeing of a keratin fiber, especially of a human keratin fiber. The mixed dyestuff is a compound having at least one chromophoric group selected from the chromophoric group of an azo-compound family and that of a tri(hetero)aryl methane family, the chromophoric group being bound with each other through the at least one linker stopping the delocalization of electrons in each chromophoric group, for example, a compound expressed by the formula in the figure. <P>COPYRIGHT: (C)2008,JPO&INPIT
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