[0001] 技术背景

[0002] 本申请为2003年8月28日美国申请NO.10/651,237的部分后续申请。

[0003] 本发明涉及基于生物样品的基因表达模式的结肠直肠癌的预后。

[0004] 结肠直肠癌是具有复杂起源的异源性疾病，结肠直肠癌患者接受治疗后复发的概率与肿瘤在肠壁浸润的程度以及结节累及的出现与否有关。这些因素也是目前进行Duke’s分期的基础。Duke’s A期病变限于结肠或直肠的粘膜下层。Duke’s B期肿瘤侵染肌肉层并且能浸润直肠或结肠肠壁。Duke’s C期疾病包括出现区域淋巴结转移以及任何程度的肠壁侵染。

[0005] 外科切除术在治疗早期的结肠直肠癌方面效果显著，对于Duke’s A期和B期患者分别有95％和75％的治愈率。Duke’s C期阳性淋巴结的存在，预示着患者在五年内复发的可能性为60％。目前对于Duke’s C期患者进行治疗的标准作法是在手术后进行化疗，这样能够将复发率降到40％-50％。但是由于相对较低的复发率，对Duke’s B期患者进行术后化疗的好处难以察觉并且依然存在争议。然而，由于Duke’s B期的分级存在一定的缺陷，大约有20-30％的这类患者表现的更像是在Duke’s C期，并且在5年内复发。

[0006] 因此显然需要一种比结节累及更好的预后因子，来区分Duke’s B期患者中可能复发的群体和将存活的群体。在Wang的美国专利申请US10/403,499中提到了利用基因表达模式进行结肠癌的预测。本说明书中提供了与之不同的基因表达模式。

[0007] 发明概述

[0008] 本发明为一种评估诊断为结肠直肠癌或接受结肠直肠癌治疗的人群中结肠直肠癌复发的可能性的方法。该方法包括对基因表达模式的分析。

[0009] 在本发明的一方面，基因表达模式包括至少7个特定的基因。

[0010] 在本发明的另一方面，基因表达模式包括至少15个特定的基因。

[0011] 在本发明的又一方面，基因表达模式包括上述的7个特定基因和15个特定的基因。在一个实施方案中，基因表达模式包括23个基因。

[0012] 用于实施本发明方法的制品也是本发明的一个方面。这些制品包括固定于机器可读介质比如计算机可读介质上的基因表达模式或其表示物。

[0013] 识别基因表达模式的制品也包括用于捕获和/或显示基因是否表达或表达的水平的基质或表面，比如微阵列。

[0014] 在本发明的再一方面的试剂盒，试剂盒中包含根据基因表达分析结肠直肠癌预后复发的试剂。

[0015] 附图简述

[0016] 图1是在根据7基因组合的实施例中所述的，由27名患者(其中14名存活，13名复发)的独立患者数据组构建的标准Kaplan-Meier图。按照芯片数据预测的结果将患者分为两类。纵轴显示每一类中无病存活患者的概率。

[0017] 图2是在根据15基因组合的实施例中所述的，由9名患者(其中6名存活，3名复发)的独立患者数据组构建的标准Kaplan-Meier图。按照芯片数据预测的结果将患者分为两类。纵轴显示在每一类中无病存活患者的概率。

[0018] 图3是根据实施例中所述的患者数据构建的标准Kaplan-Meier图，其中使用22-基因模式以及钙粘着蛋白17(Seq.ID 6)组成的基因组合。测试了36个样品(20个存活，16个复发)。根据23-基因面板的芯片数据预测的结果，将患者分为两类。纵轴显示在每一类患者中无病存活的概率。

[0019] 发明详述

[0020] 仅仅发现组织样品中特定的核酸序列存在与否并没有多少诊断或预测价值。另一方面，不同的蛋白、多肽或mRNA表达的信息正逐渐受到重视。基因组中存在具有表达蛋白、多肽或mRNA的潜在可能的核酸序列(这样的序列被称为“基因”)本身并不能决定是否在指定的细胞中表达该蛋白、多肽或mRNA。基因是否表达蛋白、多肽或mRNA以及表达到什么程度取决于许多复杂的因素。不考虑在理解和评估这些因素上的困难，检测基因的表达能够为比如肿瘤发生、转移、细胞凋亡以及其它临床相关现象等重要事件的发生提供有用信息。通过基因表达模式能够发现基因激活或失活程度的相对指标。本发明的基因表达模式用于对结肠直肠癌患者进行预后和治疗。

[0021] 需要收集患者样本制备样品。本发明方法中使用的患者样本是怀疑含有病变细胞的样本，比如来自结肠样品的原发肿瘤或来自手术边缘的上皮细胞。激光捕获显微切割(LCM)技术是一种选择待研究细胞的方法，并使由于细胞种类的异质性所导致的变异性最小化。因此，正常细胞和癌细胞在基因表达方面中度或是微小的改变均易于检测到。样本也包括在外周血中提取的循环上皮细胞。许多方法可以获得样本细胞，最优选使用Immunivest Corp公司申请的美国专利US6,136,182中的磁分离技术，在此引入其内容作为参考。一旦获得了含有目的细胞的样本，提取RNA并且扩增，并优选通过微阵列同时获得适当基因组合中基因的表达模式。

[0022] 优选的构建基因表达模式的方法包括，测定编码蛋白或多肽的基因产生的RNA的量。这可以通过逆转录酶PCR(RT-PCR)、竞争性RT-PCR、实时RT-PCR、差异显示RT-PCR、Northem Blot分析和其他相关实验实现。尽管可以使用单个PCR反应来实施这些技术，最好是扩增来自mRNA的互补DNA(cDNA)或是互补RNA(cRNA)并且通过微阵列来进行分析。大量不同的阵列构型及其生产方法已经是本领域技术人员公知的，并且公开于如下的美国专利中：US5,445,934；US5,532,128；US5,556,752；US5,242,974；US5,384,261；US5,405,783；US5,412,087；US5,424,186；US5,429,807；US5,436,327；US5,472,672；
US5,527,681；US5,529,756；US5,545,531；US5,554,501；US5,561,071；US5,571,639；
US5,593,839；US5,599,695；US5,624,711；US5,658,734和US5,700,637；在此引入其公开内容作为参考。

[0023] 微阵列技术能够同时测量上千个基因稳定状态的mRNA的水平，因而可以作为一种很好的工具用来识别失控细胞增殖的启动、抑制或调节。两种微阵列技术目前正被广泛地应用。第一种是cDNA阵列，第二种是寡核苷酸阵列。虽然这些芯片在结构上存在不同，但本质上两者其所有下游的数据分析和输出都是相同的。分析的结果通常是来自标记探针的信号强度测定结果，其中所述探针用来探测样本中与芯片已知位点的核酸序列杂交的来自样品的cDNA序列。典型地，信号的亮度与样本细胞中cDNA的含量，以及相应的mRNA的量成比例。大量这种技术是可获得的并且是有用的。优选的检测基因表达的方法公开于Linsley等的美国专利US6,271,002；Friend等的US6,218,122；Peck等的US6,218,114；和Wang等的US6,004,755中，在此引入其公开内容作为参考。

[0024] 表达水平的分析是通过比较信号的强度实现的。最好建立一个测试样本中基因表达强度相对于对照样本中基因表达强度的比值基质，例如，来自病变组织的基因表达强度可以与同类正常组织中产生的基因表达强度比较(例如，病变的结肠组织样本与正常的结肠组织样本相比较)。表达强度的比率显示了测试样本与对照样本间基因表达的倍数变化。

[0025] 基因表达模式可以用多种方式显示。最常用的方式是将原始荧光强度或比值基质排列以树状图表示，其中列表示试验样本，行表示基因。处理数据使具有相似表达模式的基因彼此相互接近。每个基因的表达比率将会用颜色标记出来。例如，小于1的比率(表明下调)将会显示为图谱上的蓝色部分，而大于1的比率(表明上调)将会显示为光谱上的红色部分。商业上可购买到的用于显示这种数据的计算机软件包括Silicon Genetics公司的“GENESPRING”以及Partek公司的“DISCOVERY”和“INFER”。

[0026] 本发明方法中所使用的被调控基因显示于实施例中。相对于不复发的患者，复发的结肠癌患者中差异表达的基因或是上调或是下调。上调或下调是相对的术语，是指基因的表达量相对某种基线有可检测到的差异(超出了检测系统的噪音影响)。在本发明中，上述基线是指在不复发患者所测量得到的基因表达量。因而在病变细胞(来自复发患者)中目的基因相对于使用相同测量方法测定的基线水平而言或是上调或是下调。本发明上下文中所述“病变”是指随着失控细胞增殖的出现，身体状态发生变化从而阻断、扰乱或是可能扰乱正常的身体机能。当患者的基因型或表型的某些方面与患有某种疾病的表现一致时就被诊断为患有该疾病。然而，实施诊断或预后还包括确定病变/状态组织，例如确定复发的可能性和治疗监控。在治疗监控方面，通过比较全过程的基因表达情况，确定基因表达模式是否发生变化，或者是否改变到与正常组织的模式更为一致来对给定疗程的效果作出临床判断。

[0027] 优选地，上调和下调的水平根据杂交的微阵列探针测量强度的成倍变化来进行区分。2.0倍的差异或是p值小于.05对于作出这种区分是优选。也就是说，当基因在病变/复发细胞中相对于正常/不复发细胞表现出表达水平差异时，其在病变细胞中的表达强度至少是正常细胞中的2倍以上，或是在正常细胞的2倍以下。优选倍数差异大的基因用于诊断或预后工具中。用于本发明的基因表达模式的基因，其产生区别于正常或非调控基因的信号的表达水平，该信号量超过临床试验仪器的背景噪音。

[0028] 统计值能够确定地将经调控基因与未调控基因和噪音进行区分。统计学试验能够识别不同样本群体间差异最大的基因。t检验是一种可靠的用于寻找两个群体间明显的差异的统计学方法。p值越低，不同组之间基因显示差异的证据就越有说服力。然而，由于微阵列每次测量不止一个基因，将有上万个统计学检测同时进行。因此，不太可能看到完全是偶然出现的小的p值，同时能够根据Sidak校正和随机/排列试验来进行p值的修正。t检验中在.05以下的p值是该基因存在显著差异的证据。经过Sidak因子校正后小于.05的p值则是更加显著的证据。当每个群体中均有大量的样本存在时，随机/排列试验后在0.05以下的p值是存在明显差异最具说服力的证据。

[0029] 用于选择能够产生比非调控基因或噪音产生的信号更强信号的基因的另一个参数是使用绝对信号差异值。优选地，受调控的基因表达产生的信号至少与正常或非调控基因的信号有20％的差异(在绝对值的基础上)。更优选地，上述基因与正常或非调控基因的表达模式间至少有30％的差异。

[0030] 基因被分为几组，从一组基因中获得的一套基因的信息可以作为进行诊断、预后或治疗选择等临床判断的可靠的基础。这些套基因构成了发明的基因组合。本发明中，根据所用基因组合作出的判断包括对结直肠癌及其复发概率的判断，最优选对Duke B期患者进行判断。象常见的诊断标记一样，通常希望能够仅使用最少量的标记即可足以进行正确的医学判断。这避免了使用那些悬而未决需作进一步分析的治疗措施带来的延误，同时又避免了时间和资源的不合理使用。

[0031] 优选地，构建这样的组合以致该组合中的基因组合相对于单个基因或随机的基因组合而言，具有更好的灵敏度和特异性。在本发明中，组合的灵敏度反映在基因在病变状态下相对于正常状态下所表现出的基因表达的倍数差异上。特异性反映于基因表达信号与目的情况相关程度的统计学测量中。例如，标准偏差能够用于这种测量。对于在一个基因组合中的一组基因，表达测量值的标准偏差越小其特异性越大。检测其他变量比如相关系数也能够实现同样的功能。

[0032] 一种建立基因表达组合的方法是通过使用优化算法，例如常用于建立股票投资组合的平均方差算法。该方法在Tim Jatkoe等人于2003年3月21日申请的名为“组合选择”的专利申请中有详细的描述。基本上，该方法需要建立一组输入值(金融应用中的股票，本发明中指通过强度测定的表达)并且优化回报值(例如产生的信号)，对其进行接收并使用，同时最小化回报值的可变性。许多商务软件可以进行这种操作。优选使用“Wagner联合均值-方差优化应用程序”，本说明书中将其简称为“Wagner软件”。该软件优选使用“Wagner联合均值-方差优化应用程序”的函数来测定有效界值和Markowitz意义上优选的优化组合。使用软件时需要转换微阵列数据以便其能够作为输入处理，如同将软件用作预期的金融分析目的时进行股票回报和风险检测的方式相同。

[0033] 在选择基因组合的过程中也可以使用直接推断规则。优选的，该规则在生物学和对产生临床结果的技术的理解的基础上进行公式化。更优选地，它们用于优化方法的输出。例如，组合选择的平均方差法，能够用于分析结肠直肠癌患者中大量基因差异表达的微阵列数据。该方法获得的输出是一组优化了的基因，其中包括一些在外周血和病变组织中都表达的基因。如果用于测试方法的样本来自于外周血，而一些在乳腺癌样本中差异表达的基因在外周血中同样也差异表达，此时可使用直接推断规则，其中从去除了在外周血中差异表达基因的有效界值中，选择基因组合。当然，该规则也可以在有效界值生成前使用，例如在数据预选的时候应用该规则。

[0034] 其他与所述生物学问题无关的直接推断规则同样能被应用。例如，能够应用基因组合中仅有一定比例能够被一个或一组特殊的基因表示的规则。商业软件例如Wagner软件能够容易的提供这种直接推断规则。这是很有用的，例如，当除了准确性和精密度以外的其他因素(例如预期许可费)对包括一个或多个基因的需求有影响的时候。

[0035] 本发明的方法包括通过比较不同基因(或基因组合)的基因表达模式进行预测。组成基因组合的每个基因的基因表达模式固定在介质上，例如计算机可读的介质。其存在许多种形式。例如，可以建立表格，其输入值表示疾病的信号范围(例如强度值)。真实患者的数据用来与表格中的值进行比较，以判断患者样本是正常的还是发生了病变。在更复杂的实施方案中，表达信号(如荧光强度)的模式以数字化或图形化的形式记录下来。与患者样本结合的基因组合中的基因表达模式用来与上述表达模式比较。应用模式比较软件来判断是否患者样本具有显示疾病复发的模式。当然，这些比较也能用来判断是否患者不可能复发疾病。然后将样本的表达模式与对照细胞的基因组合相比较。如果样本表达模式与结肠直肠癌复发的表达模式一致时，那么(在缺乏其它医学考虑的情况下)患者将被当作即将复发的患者来进行治疗。如果样本表达模式与正常/对照细胞的表达模式一致时，患者将诊断为结直肠癌阴性。

[0036] 本发明优选的表达模式为表2中给出的7基因组合和表3中给出的15基因组合。更优选，使用将上述7基因与15基因组合起来构成的基因组合。最优选，由其它能够独立检验结直肠预后的基因，如钙粘着蛋白17(Seq.ID No.6)与表2和表3中给出的基因组合组成的基因表达组合(表4)。该最优选的组合能够最好的区分Duke’s B期患者中复发高危群体与不会复发的群体。一旦确定了高危患者，将能够通过辅助性疗法对其进行治疗。其它能够替代钙粘着蛋白17的独立预后鉴定基因包括，但不限于，序列为Seq ID No.29-94的基因。

[0037] 本发明中，最优选的分析患者基因表达模式进行结肠癌预测的方法是通过使用Cox风险分析程序。最优选地，该分析使用S-Plus软件(可购于Insightful公司)进行。使用该方法，对基因表达模式与足以表明复发的表达模式(即模式中基因组合的表达水平预示了复发)进行比较。使用已经确定了临界值的Cox风险模型比较两种模式的相似性(已知复发的与患者比较)，判断患者的模式是否超过了临界值。如果超过了，那么患者将被确定为会复发的病人并且进行相应的治疗，例如辅助性治疗。如果患者的表达模式没有超过临界值，那么他们将被确定为不会复发的病人。其他的分析工具也能用来解决该问题，例如线性鉴别分析，逻辑回归分析以及神经网络方法。

[0038] 许多其它常见的模式识别方法也是可行的。下面的参考文件提供了其中的一些例子：

[0039] 加权表决：

[0040] Golub，TR.，Slonim，DK.，Tamaya，P.，Huard，C.，Gaasenbeek，M，Mesirov，JP.，Coller，H.，Loh，L.，Downing，JR.，Caligiuri，MA.，Bloomfield，CD.，Jander，ES.癌症的分子分级：通过检测基因的表达进行等级的确定和预测.Science 286：531-537，1999[0041] 支持矢量机器：

[0042] Su，AI.，Welsh，JB.，Sapinoso，LM.，Kem，SG.，Dimitrov，P.，Lapp，H.，Schultz PG.，Powell，SM.，Moskaluk，CA.，Frierson，HF.Jr.，Hampton，GM.使用基因表达信号进行人类癌症的分子分级.Cancer Research 61：77388-93，2001

[0043] Ramaswamy，S.，Tamayo，P.，Rifkin，R.，Mukherjee，S.，Yeang，CH.，Angelo，M.，Ladd，C.，Reich，M.，Latulippe，E.，Mesirov，JP.，Poggio，T.，Gerald，W.，Loda，M.，Lander，ES.，Gould，TR.根据肿瘤基因表达信号诊断多类癌症Proceedings of National Academy ofSciences of the USA 98：15149-15154，2001

[0044] K-最临近值：

[0045] Ramaswamy，S.，Tamayo，P.，Rifkin，R.，Mukherjee，S.，Yeang，CH.，Angelo，M.，Ladd，C.，Reich，M.，Latulippe，E.，Mesirov，JP.，Poggio，T.，Gerald，W.，Loda，M.，Lander，ES.，Gould，TR.根据肿瘤基因表达信号诊断多类癌症Proceedings of the NationalAcademy of Sciences of the USA 98：15149-15154，2001

[0046] 相关系数

[0047] van’t Veer LJ，Dai H，van de Vijver MJ，He YD，Hart AA，Mao M，Peterse HL，vander Kooy K，Marton MJ，Witteveen AT，Schreiber GJ，Kerkhoven RM，RobertsC，Linsley PS，Bemards R，Friend SH.根据基因表达模式预测乳腺癌的临床结果.Nature.2002 Jan 31；415(6871)：530-6.

[0048] 本发明中的基因表达模式同样可以与其它的用于癌症诊断、预后或治疗监控的非遗传诊断方法联合使用。例如，在一些情况下将上述基于基因表达的诊断方法与传统标记如血清蛋白标记(例如癌胚抗原)的数据结合是很有益的。有很多种这样的标记物其中包括CEA分析物。在一种上述方法中，治疗的患者被定期抽血，而后进行上述一种血清标记的酶免疫测定。当标记的浓度显示肿瘤复发或是治疗失败，对样本源作基因表达分析。在怀疑肿块存在的地方，进行针吸采样，对从肿块中获得的细胞的基因表达模式进行上述分析。可选择地，组织样本也能够从以前进行肿瘤切除的组织附近的区域中提取。这种方法在使用其他测试结果不明确的时候尤其有效。

[0049] 本发明的制品包括用于治疗、诊断、预后以及其他疾病评估的基因表达模式的表示物。表达模式的表示物将归结为能够被机器自动读取的介质，例如计算机可读介质(磁盘，光盘等等)。本发明的制品还包括分析这些介质上基因表达模式的操作指南。例如，制品包括具有比较上述基因组合中基因表达模式的计算机操作指南的CD-ROM。制品也包括数字记录的基因表达模式，以用于与来自患者样本的基因表达数据进行比较。可选择地，表达模式可以用不同的表现格式记录。图形记录是其中的一种。像整合在上述Partek公司的软件“DISCOVERY”和“INFER”中的聚类算法就能最好的协助显示这类数据。

[0050] 本发明不同类型的制品是用来显示基因表达模式的介质或格式化检测。例如，这些可以包括微阵列，其中互补序列或探针被固定在基质上，当与目的基因的序列结合后能产生表示其存在的可读信号。可选择地，本发明的制品包括试剂盒，其能够进行杂交、扩增以及产生表明目的基因表达水平的信号以判断结肠直肠癌。

[0051] 本发明制备的试剂盒包括用于测定基因表达模式的格式化检测。其中包括进行检测所需的全部或部分材料，例如试剂和操作指南。

[0052] 本发明进一步用下列非限定性的实施例说明。

[0053] 实施例：本发明的基因分析典型地与编码蛋白或多肽产物的全长核酸序列相关。但本领域技术人员知道从分析的观点而言鉴定全长序列不是必需的。也就是说，根据公知的原则，部分序列或ESTs同样能够选作用来设计评估相应基因的基因表达的探针。

[0054] 实施例1样本处理和LCM

[0055] 收集来自于外科切除结肠直肠癌肿瘤患者的新鲜冷冻组织样本。使用的样本来自63个根据标准诊断学和病理学被划分为Duck’s B期的患者。患者的临床结果是已知的。
36名患者超过3年没有复发，而27名患者在3年内出现了肿瘤复发的情况。

[0056] 在获得组织后的20-30分钟内快速用液氮将其冷冻，并且随后保存在-80℃的条件下。为了能够激光捕获，将样本切片(6μm)，其中一片封固于载玻片上，另一片封固于薄膜上(P.A.L.M.)，该薄膜已经被固定在载玻片上(Micro Slides Colorfrost，VWR Scientific，Media，PA)。封固于载玻片上的切片于冷的丙酮中固定，并且用Mayer’s苏木精(Sigma，St.Louis，MO)染色。病理学家通过分析样本进行诊断和分级。根据附带的外科病理学和临床报告进行临床分级评估以核实Dukes分类。封固于薄膜上的切片在100％的乙醇中固定5分钟，于曙红/100％乙醇(100μg曙红溶于100ml无水乙醇)中负染1分钟，在100％乙醇中快速浸泡一次以除去未结合的染料，空气中干燥10分钟。

[0057] 用 于LCM 前，膜 (LPC-MEMBRANE PEN FOIL 1.35μm No 8100，P.A.L.M.GmbH Mikrolaser Technologie，Bernried，Germany)和载玻片需进行预处理以除去RNA酶，并且增强组织样本在膜上的附着。简要地说，载玻片用DEP H2O洗涤，膜用RNase AWAY(Molecular Bioproducts，公司，SanDiego，CA)洗涤并在DEP H2O中漂洗。在将膜附着在载玻片以后，玻载片于+120℃烘烤8小时，用TI-SAD(Diagnostic Products Corporation，LosAngeles，CA，1∶50溶于DEP H2O中，脱脂棉花过滤)处理，+37℃温育30分钟。使用前，需在膜上封固组织样本的位置涂布10μl的RNA酶抑制溶液(Rnasin Inhibitor 2500U ＝ 33U/μl N211A，Promega GmbH，Mannheim，Germany，0.5μl 溶 于
400μl冰冷的溶液中，包括0.15mol NaCl，10mmol TrispH8.0，0.25mmol二硫苏糖醇)。

[0058] 封固于膜上的组织切片用于进行LCM。使用PALM自动微光束技术(P.A.L.M.Mikrolaser Technologie，Carl Zeiss，公司，Thomwood，NY)，能够捕获大约2000个上皮细胞/样本，并连接到Zeisis Axiovert 135显微镜中(Carl ZeissJena GmbH，Jena，Germany)。其中包括正常粘膜的周围基质与癌症样本中偶然的干扰基质成分。捕获的细胞置于100％乙醇的小管中于-80℃保存。

[0059] 实施例2RNA提取与扩增

[0060] 使用Zymo-Spin Column(Zymo Research，Orange，CA 92867)从LCM捕获的样本中提取总RNA。大约2ng的总RNA重悬于10μl水中，并使用T7RNA聚合酶进行2轮扩增，从而获得大约50μg的扩增RNA。

[0061] 实施例3DNA微阵列杂交与定量

[0062] 用可商购的Affymetrix公司的人U133a，通过由大约23,000个人DNA克隆组成的一组DNA微阵列测定样本。根据前述方法制备并获得的总RNA用于所述芯片，使用Agilent BioAnalyzer参照产品说明书进行分析。所有63个样本均符合质量控制标准，并且其数据被用于标记的选择。

[0063] 芯片强度数据通过Fffymetrix公司的软件MAS VERSION 5.0进行分析。通过自动的分析确定了两个能够用以区分复发患者与不复发患者的基因。

[0064] 上述获得的芯片强度数据作为PARTEK 5.1等商业自动聚类软件的输入值。使用该自动聚类算法识别有20个患者的高复发率群体(13个复发，7个存活)。从最初的23,000个基因中，t检验分析选出了276个在这些病人中显著差异表达的基因。其中，两个基因能够最好地区分复发患者与不复发患者：人肠肽相关转运蛋白(Seq.ID.No.3)和人脂肪酸结合蛋白1(Seq.ID No.1)。这两个基因在该患者群体中的复发患者中下调(实际上是被关闭或是没有表达)。

[0065] 在余下的43名患者中采用手动分析以进一步的区分复发患者与不复发患者。这组患者的数据被进一步分为以下两组：27名患者被分到训练组，16名患者被分到测试组。这保证了不会将相同的数据同时用于确定标记和检验标记的效用。

[0066] 不等方差t检验用于训练组。从具有有效的校正p值的28个基因中选出MHC II-DR-B。这些基因在复发患者中下调。MHC II-DR-B(Seq.IDNo.2)也具有最小的p值。

[0067] 在另一轮的手动分析过程中，使用上述的Partek Version 5.0软件运行变量选择程序进行线性鉴别分析以区分训练组的存活和复发患者。搜寻的方法采用预选。用最小后验误差选择的变量为免疫球蛋白样转录物5蛋白(Seq.ID No.4)。Cox比例风险模型(使用Insightful公司的“S Plus”软件)用于基因选择以确定上述基因选择的存活时间。在全部27轮的每一轮中，训练组中27个患者中的一个被取出，剩下的26个患者被用于单变量Cox模型回归以评估基因表达与患者存活时间之间的关联度。该关联度由从Cox模型回归返回的相应的标准参数估计值和P值评估。0.01的P值作为界限用来从每一轮排除一个样本的基因选择中选取上基因(top gene)。比较每一轮挑选出的上基因(top gene)，选出在全部27轮排除一个基因的选择循环中至少有26次被选中的基因。总共70个基因被选出，并且MHC II-DR-B与免疫球蛋白样转录物5蛋白均在其中(又显示为下调)。

[0068] 构建多基因预测因子：MHC II-DR-B与免疫球蛋白样转录物5蛋白这两个基因用于通过线性鉴别分析产生预测因子。投票值表示复发的后验概率。当患者的值大于0.5时被认为是复发患者。当患者的值小于于0.5时则被认为是存活患者。该预测因子在训练组中进行测验。

[0069] 交叉确认和预测因子评估：预测因子的性能将在独立的数据组中进行测定，因为多数的分类方法均在构建它的实例中效果良好。16名患者的测试组用来评估预测的准确性。分类的中止由ROC曲线来决定。选择中止后，将确定测试组中准确预测的复发和存活患者数量。

[0070] 全面预测：对63个Duke’s B期结肠癌患者的基因表达模式进行分析，确定了在患者中差异表达的4个基因(下调或关闭)。这些基因是Seq.IDNo.1，Seq.ID No.2，Seq.ID No.3和Seq.ID No.4。36名患者在3年以上病情没有复发，而27名患者在3年内肿瘤复发。使用Seq.ID No.2，Seq.ID No.3和Seq.ID No.4这3个基因标记组合进行预测，27个复发患者中的22个以及36个存活患者中的27个能够被正确的确定。这一结果显示了82％的灵敏度和75％的特异性。阳性预测值为71％，阴性预测值为84％。

[0071] 实施例4：更多的样本

[0072] 对74名已编号的Dukes’B结肠癌患者的冰冻肿瘤样本进行研究。外科手术时收集原发肿瘤以及附近无瘤结肠组织。对每个样本重新进行组织病理学分析以确定诊断结果以及肿瘤累及的一致性。选择用于分析的区域包含超过50％的肿瘤细胞结构并且没有混入其它组织。还可以获得一致性的后续信息。

[0073] 实施例5：基因表达分析

[0074] 根据实施例1-3中描述的方法从实施例4的样本中提取总RNA。阵列用标准的Affymetrix方法和扫描仪进行扫描。为了进行后续分析，每个探针组被当作一个分离的基因。通过Affymetrix GeneChip分析软件MAS 5.0计算每个基因的表达值。所有用于后续分析的数据均符合质量控制标准。

[0075] 统计学方法

[0076] 基因表达数据首先通过变量筛选以除去在所有样本中均“不存在”的基因。在22,000个基因中，17,616个基因通过了筛选用于聚类。在分级聚类前，每个基因根据患者的中间表达水平进行划分。在至少10％患者中的表达水平超过平均表达水平4倍以上变化的基因用于聚类。为了确定具有不同基因表达模式的子患者群，分别使用软件GeneSpring
5.0(SanJose，CA)和Partek 5.1(St.Louis，MO)进行平均连锁分级聚类和k平均值聚类。
使用经过Bonferroni修正的T检验，根据聚类结果识别在两个子患者群中具有不同表达水平的基因。Bonferroni修正P值为0.01被选作基因选择的界限。每类中具有不同表达模式的患者将进一步根据输出信息进行检查。

[0077] 为了鉴定能够区分复发患者和存活患者的基因标记，每个子患者群分开进行下面的分析。所有的统计学分析都是通过软件S-Plus(Insightful，VA)进行的。

[0078] 患者与肿瘤性质

[0079] 表1中列出了患者的临床和病理学特征以及肿瘤的情况。包括的信息有患者的年龄、性别、TNM阶段、等级、肿瘤大小和肿瘤的位置。74名患者中有73名有测定的淋巴结数量的数据，74名患者中有72名有估计的肿瘤大小信息。复发患者与存活患者间在病情和肿瘤特征方面没有显著差异。没有患者接受过手术前治疗。研究中所有的患者都具有接下来最少3年的病情数据。

[0080] 根据基因表达模式鉴定子患者群

[0081] 自动分级聚类分析根据17,000个主要基因的表达模式相似性生成了含有74名患者的群。其中确定了两个子患者群，子群间有超过600个差异表达的基因(p＜0.00001)。较大的子群和较小的子群分别包括54名和20名患者。在含有54名患者的较大子群中仅有18名患者(33％)在3年内肿瘤复发，而在含有20名患者的较小子群中有13名患者(65％)出现了后续病变。卡方分析给出了0.028的p值。

[0082] 筛选和检测出了两个主要的基因群，其在两类肿瘤间有明显不同的表达。第一个基因群在20名患者的较小子群中含有一组下调的基因，例如肝肠特异性钙粘着蛋白17、脂肪酸结合蛋白1、尾类同源框转录因子(caudaltype homeo box transcription factor)CDX1和CDX2、粘蛋白和类钙粘着蛋白MUCDHL。第二个基因群以一组在较小患者子群中上调的基因为代表，包括血清诱导激酶SNK、膜联蛋白A1、B细胞RAG相关蛋白、钙结合蛋白2和肿瘤抗原L6。有20名患者较小的的子群根据基因表达模式代表低分化的肿瘤。

[0083] 基因信号及其预测值

[0084] 为了鉴定能够区分复发患者与存活患者的基因标记，分别单独分析每个患者子群。每个子群的患者首先被分为训练组和测试组，两组中患者的数量大致相同。训练组用于筛选基因标记并且建立预后信号。测试组用于进行独立的检验。在含有54名患者的较大子群中，有36名患者在首次诊断后至少3年没有复发，而18名患者在3年内出现了肿瘤复发。这54名患者被分为两组。训练组中含有21名存活患者和6名复发患者。在较小的含有20名患者的子群中，7名患者在至少3年内没有复发和13名患者在3年内出现肿瘤复发。这20名患者被分为两组。训练组中含有4名存活患者和7名复发患者。为了确定一个基因信号以区分预后良好的群体和预后不良的群体，手动的分类方法应用于每个训练组。单变量Cox比例风险回归被用来确定表达水平与患者存活时间相关的基因。基因的选择以p值小于0.02为选择标准。然后，对选择的基因进行t检验以测定在复发患者和存活患者间差异表达的显著性(P<0.01>。为了避免选择的基因只适合该训练组，重新取样100次进行t检验以找到在超过80％的重新取样测试中具有显著p值的基因。在含有27名患者的训练组中选出了7个基因(表2)，在含有11名患者的训练组中选出了15个基因(表3)。根据这22个基因和钙粘着蛋白17，用S-Plus软件构建Cox模型来预测患者的复发情况。Kaplan-Meier存活分析显示，预测为预后良好的群体与预测为预后不良的群体间患者存活的概率存在明显的差异。

[0085] 其中几个基因与细胞增殖和肿瘤发生有关。例如，酪氨酸3单加氧酶色氨酸5单加氧酶激活蛋白(YWHAH)属于14-3-3蛋白家族，其与人类细胞DNA损伤后的G2细胞周期控制有关。RCC1是另一个细胞周期基因，其参与调控染色体凝聚的启动。BTEB2是一种锌指转录因子，其被认为是β连环蛋白不依赖的Wnt-1应答基因。少量基因可能参与局部免疫应答。免疫球蛋白样转录物5蛋白是一种常见的MHC I分子抑制受体。CAPG是凝溶胶蛋白/绒毛蛋白家族帽状蛋白的唯一成员，其主要在巨噬细胞中表达。LAT是高酪氨酸磷酸化蛋白，其连接T细胞受体导致细胞活化。这样肿瘤细胞和免疫细胞表达的基因均可作为预测因子来判断患者的复发情况。

[0086] 为了检验23-基因的预后信号，将27名患者的较大子群和9名患者的较小子群的两个测试组的患者被合并在一起，所做的预测结果均是根据测试组中这36名独立患者作出的。该测试组中包括18名在3年内肿瘤复发的患者和18名3年以上没有复发的患者。预测的结果是有13个正确的复发分类和15个正确的存活分类。整体的准确率为78％(36名中的28名)，其中灵敏度为72％(18名中的13名)，特异性为83％(18名中的15名)。
这一性能显示在Dukes’B期患者中，测量值低于预后信号极限的患者在3年内肿瘤复发的概率比测量值高于预后信号极限的患者高13倍(95％CI：2.6，65；P＝0.003)。此外，Kaplan-Meier存活分析显示，预测为预后良好的群体与预测为预后不良的群体间患者存活的概率存在显著差异(P＜0.0001)。在多变量Cox比例风险回归中，肿瘤复发的估计风险率为0.41(95％置信区间，0.24到0.71；P＝0.001)，表明23-基因组代表了预后信号，而且它与更高的肿瘤复发率负相关。使用含有7个基因的组合(表2)，可以得到83％的灵敏度和80％的特异性(根据12个复发者和15个存活者的样本组)。使用含有15个基因的组合(表3)，可以得到50％的灵敏度和100％的特异性(根据6个复发者和3个存活者的样本组)。图1和2图形显示了分别对含7基因组合和15基因组合进行Kaplan-Meier分析的图形描述。

[0087] 此外，如这些结果所示，可以通过分析原发肿瘤的基因表达模式进行预后判断。

[0088] 表1.患者及其肿瘤的临床和病理学特征

[0089]* 2

[0090] 年龄、淋巴结数量和肿瘤信息的P值是通过t检验获得的；其他的P值是通过x检验得到。

[0091] 表2：7基因列表

[0092]

[0093] 表3：15基因列表

[0094]

[0095] 表4. 23个基因构成的预测信号

[0096]

[0097] 序列表

[0098] <110>奥索临床诊断有限公司

[0099] Wang，Yixin

[0100] <120>结肠直肠癌预后

[0101] <130>ADS-5003 US NP

[0102] <140>tbd

[0103] <141>2003-08-27

[0104] <160>94

[0105] <170>PatentIn version 3.1

[0106] <210>1

[0107] <211>489

[0108] <212>DNA

[0109] <213>人

[0110] <400>1

[0111] agagccgcag gtcagtcgtg aagagggagc tctattgcca ccatgagttt ctccggcaag 60[0112] taccaactgc agagccagga aaactttgaa gccttcatga aggcaatcgg tctgccggaa 120[0113] gagctcatcc agaaggggaa ggatatcaag ggggtgtcgg aaatcgtgca gaatgggaag 180[0114] cacttcaagt tcaccatcac cgctgggtcc aaagtgatcc aaaacgaatt cacggtgggg 240[0115] gaggaatgtg agctggagac aatgacaggg gagaaagtca agacagtggt tcagttggaa 300[0116] ggtgacaata aactggtgac aactttcaaa aacatcaagt ctgtgaccga actcaacggc 360[0117] gacataatca ccaataccat gacattgggt gacattgtct tcaagagaat cagcaagaga 420[0118] atttaaacaa gtctgcattt catattattt tagtgtgtaa aattaatgta ataaagtgaa 480[0119] ctttgtttt 489[0120] <210>2

[0121] <211>853

[0122] <212>DNA

[0123] <213>人

[0124] <400>2

[0125] gcctgctgct ctggcccctg gtcctgtcct gttctccagc atggtgtgtc tgaggctccc 60[0126] tggaggctcc tgcatggcag ttctgacagt gacactgatg gtgctgagct ccccactggc 120[0127] tttggctggg gacaccagac cacgtttctt ggagtactct acgtctgagt gtcatttctt 180[0128] caatgggacg gagcgggtgc ggtacctgga cagatacttc cataaccagg aggagaacgt 240[0129] gcgcttcgac agcgacgtgg gggagttccg ggcggtgacg gagctggggc ggcctgctgc 300[0130] ggagcactgg aacagccaga aggacctcct ggagcagaag cggggccggg tggacaacta 360[0131] ctgcagacac aactacgggg ttgtggagag cttcacagtg cagcggcgag tccatcctaa 420[0132] ggtgactgtg tatccttcaa agacccagcc cctgcagcac cataacctcc tggtctgttc 480[0133] tgtgagtggt ttctatccag gcagcattga agtcaggtgg ttccggaatg gccaggaaga 540[0134] gaagactggg gtggtgtcca caggcctgat ccacaatgga gactggacct tccagaccct 600[0135] ggtgatgctg gaaacagttc ctcggagtgg agaggtttac acctgccaag tggagcaccc 660[0136] aagcgtgaca agccctctca cagtggaatg gagagcacgg tctgaatctg cacagagcaa 720[0137] gatgctgagt ggagtcgggg gctttgtgct gggcctgctc ttccttgggg ccgggctgtt 780[0138] catctacttc aggaatcaga aaggacactc tggacttcag ccaagaggat tcctgagctg 840[0139] aagtgcagat gac 853[0140] <210>3

[0141] <211>3345

[0142] <212>DNA

[0143] <213>人

[0144] <400>3

[0145] gaattccgtc tcgaccactg aatggaagaa aaggactttt aaccaccatt ttgtgactta 60[0146] cagaaaggaa tttgaataaa gaaaactatg atacttcagg cccatcttca ctccctgtgt 120[0147] cttcttatgc tttatttggc aactggatat ggccaagagg ggaagtttag tggacccctg 180[0148] aaacccatga cattttctat ttatgaaggc caagaaccga gtcaaattat attccagttt 240[0149] aaggccaatc ctcctgctgt gacttttgaa ctaactgggg agacagacaa catatttgtg 300[0150] atagaacggg agggacttct gtattacaac agagccttgg acagggaaac aagatctact 360[0151] cacaatctcc aggttgcagc cctggacgct aatggaatta tagtggaggg tccagtccct 420[0152] atcaccatag aagtgaagga catcaacgac aatcgaccca cgtttctcca gtcaaagtac 480[0153] gaaggctcag taaggcagaa ctctcgccca ggaaagccct tcttgtatgt caatgccaca 540[0154] gacctggatg atccggccac tcccaatggc cagctttatt accagattgt catccagctt 600[0155] cccatgatca acaatgtcat gtactttcag atcaacaaca aaacgggagc catctctctt 660[0156] acccgagagg gatctcagga attgaatcct gctaagaatc cttcctataa tctggtgatc 720[0157] tcagtgaagg acatgggagg ccagagtgag aattccttca gtgataccac atctgtggat 780[0158] atcatagtga cagagaatat ttggaaagca ccaaaacctg tggagatggt ggaaaactca 840[0159] actgatcctc accccatcaa aatcactcag gtgcggtgga atgatcccgg tgcacaatat 900[0160] tccttagttg acaaagagaa gctgccaaga ttcccatttt caattgacca ggaaggagat 960[0161] atttacgtga ctcagccctt ggaccgagaa gaaaaggatg catatgtttt ttatgcagtt 1020[0162] gcaaaggatg agtacggaaa accactttca tatccgctgg aaattcatgt aaaagttaaa 1080[0163] gatattaatg ataatccacc tacatgtccg tcaccagtaa ccgtatttga ggtccaggag 1140[0164] aatgaacgac tgggtaacag tatcgggacc cttactgcac atgacaggga tgaagaaaat 1200[0165] actgccaaca gttttctaaa ctacaggatt gtggagcaaa ctcccaaact tcccatggat 1260[0166] ggactcttcc taatccaaac ctatgctgga atgttacagt tagctaaaca gtccttgaag 1320[0167] aagcaagata ctcctcagta caacttaacg atagaggtgt ctgacaaaga tttcaagacc 1380[0168] ctttgttttg tgcaaatcaa cgttattgat atcaatgatc agatccccat ctttgaaaaa 1440[0169] tcagattatg gaaacctgac tcttgctgaa gacacaaaca ttgggtccac catcttaacc 1500[0170] atccaggcca ctgatgctga tgagccattt actgggagtt ctaaaattct gtatcatatc 1560[0171] ataaagggag acagtgaggg acgcctgggg gttgacacag atccccatac caacaccgga 1620[0172] tatgtcataa ttaaaaagcc tcttgatttt gaaacagcag ctgtttccaa cattgtgttc 1680[0173] aaagcagaaa atcctgagcc tctagtgttt ggtgtgaagt acaatgcaag ttcttttgcc 1740[0174] aagttcacgc ttattgtgac agatgtgaat gaagcacctc aattttccca acacgtattc 1800[0175] caagcgaaag tcagtgagga tgtagctata ggcactaaag tgggcaatgt gactgccaag 1860[0176] gatccagaag gtctggacat aagctattca ctgaggggag acacaagagg ttggcttaaa 1920[0177] attgaccacg tgactggtga gatctttagt gtggctccat tggacagaga agccggaagt 1980[0178] ccatatcggg tacaagtggt ggccacagaa gtaggggggt cttccttaag ctctgtgtca 2040[0179] gagttccacc tgatccttat ggatgtgaat gacaaccctc ccaggctagc caaggactac 2100[0180] acgggcttgt tcttctgcca tcccctcagt gcacctggaa gtctcatttt cgaggctact 2160[0181] gatgatgatc agcacttatt tcggggtccc cattttacat tttccctcgg cagtggaagc 2220[0182] ttacaaaacg actgggaagt ttccaaaatc aatggtactc atgcccgact gtctaccagg 2280[0183] cacacagact ttgaggagag ggcgtatgtc gtcttgatcc gcatcaatga tgggggtcgg 2340[0184] ccacccttgg aaggcattgt ttctttacca gttacattct gcagttgtgt ggaaggaagt 2400[0185] tgtttccggc cagcaggtca ccagactggg atacccactg tgggcatggc agttggtata 2460[0186] ctgctgacca cccttctggt gattggtata attttagcag ttgtgtttat ccgcataaag 2520[0187] aaggataaag gcaaagataa tgttgaaagt gctcaagcat ctgaagtcaa acctctgaga 2580[0188] agctgaattt gaaaaggaat gtttgaattt atatagcaag tgctatttca gcaacaacca 2640[0189] tctcatccta ttacttttca tctaacgtgc attataattt tttaaacaga tattccctct 2700[0190] tgtcctttaa tatttgctaa atatttcttt tttgaggtgg agtcttgctc tgtcgcccag 2760[0191] gctggagtac agtggtgtga tcccagctca ctgcaacctc cgcctcctgg gttcacatga 2820[0192] ttctcctgcc tcagcttcct aagtagctgg gtttacaggc acccaccacc atgcccagct 2880[0193] aatttttgta tttttaatag agacggggtt tcgccatttg gccaggctgg tcttgaactc 2940[0194] ctgacgtcaa gtgatctgcc tgccttggtc tcccaataca ggcatgaacc actgcaccca 3000[0195] cctacttaga tatttcatgt gctatagaca ttagagagat ttttcatttt tccatgacat 3060[0196] ttttcctctc tgcaaatggc ttagctactt gtgtttttcc cttttggggc aagacagact 3120[0197] cattaaatat tctgtacatt ttttctttat caaggagata tatcagtgtt gtctcataga 3180[0198] actgcctgga ttccatttat gttttttctg attccatcct gtgtcccctt catccttgac 3240[0199] tcctttggta tttcactgaa tttcaaacat ttgtcagaga agaaaaaagt gaggactcag 3300[0200] gaaaaataaa taaataaaag aacagccttt tgcggccgcg aattc 3345[0201] <210>4

[0202] <211>1924

[0203] <212>DNA

[0204] <213>人

[0205] <400>4

[0206] ccatgacgcc cgccctcaca gccctgctct gccttgggct gagtctgggc cccaggaccc 60[0207] gcatgcaggc agggcccttc cccaaaccca ccctctgggc tgagccaggc tctgtgatca 120[0208] gctgggggag ccccgtgacc atctggtgtc aggggagcct ggaggcccag gagtaccaac 180[0209] tggataaaga gggaagccca gagccctggg acagaaataa cccactggaa cccaagaaca 240[0210] aggccagatt ctccatccca tccatgacac agcaccatgc agggagatac cgctgccact 300[0211] attacagctc tgcaggctgg tcagagccca gcgaccccct ggagctggtg atgacaggat 360[0212] tctacaacaa acccaccctc tcagccctgc ccagccctgt ggtggcctca ggggggaata 420[0213] tgaccctccg atgtggctca cagaagggat atcaccattt tgttctgatg aaggaaggag 480[0214] aacaccagct cccccggacc ctggactcac agcagctcca cagtgggggg ttccaggccc 540[0215] tgttccctgt gggccccgtg acccccagcc acaggcgtgt ctaggaagcc ctccctcctg 600[0216] accctgcagg gccctgtcct ggcccctggg cagagcctga ccctccagtg tggctctgat 660[0217] gtcggctacg acagatttgt tctgtataag gagggggaac gtgacttcct ccagcgccct 720[0218] ggccagcagc cccaggctgg gctctcccag gccaacttca ccctgggccc tgtgagccgc 780[0219] tcctacgggg gccagtacag gtgctatggt gcacacaacc tctcctccga gtggtcggcc 840[0220] cccagtgacc ccctggacat cctgatcaca ggacagatct atgacaccgt ctccctgtca 900[0221] gcacagccgg gccccacagt ggcctcagga gagaacatga ccctgctgtg tcagtcacgg 960[0222] gggtattttg acactttcct tctgaccaaa gaaggggcag cccatccccc actgcgtctg 1020[0223] agatcaatgt acggagctca taagtaccag gctgaattcc ccatgagtcc tgtgacctca 1080[0224] gcccacgcgg ggacctacag gtgctacggc tcacgcagct ccaaccccca cctgctgtct 1140[0225] ttccccagtg agcccctgga actcatggtc tcaggacact ctggaggctc cagcctccca 1200[0226] cccacagggc cgccctccac acctggtctg ggaagatacc tggaggtttt gattggggtc 1260[0227] tcggtggcct tcgtcctgct gctcttcctc ctcctcttcc tcctcctccg acgtcagcgt 1320[0228] cacagcaaac acaggacatc tgaccagaga aagactgatt tccagcgtcc tgcaggggct 1380[0229] gcggagacag agcccaagga caggggcctg ctgaggaggt ccagcccagc tgctgacgtc 1440[0230] caggaagaaa acctctagcc cacacgatga agacccccag gcagtgacgt atgccccggt 1500[0231] gaaacactcc agtcctagga gagaaatggc ctctcctccc tcctcactgt ctggggaatt 1560[0232] cctggacaca aaggacagac aggtggaaga ggacaggcag atggacactg aggctgctgc 1620[0233] atctgaagcc tcccaggatg tgacctacgc ccagctgcac agcttgaccc ttagacggaa 1680[0234] ggcaactgag cctcctccat cccaggaagg ggaacctcca gctgagccca gcatctacgc 1740[0235] cactctggcc atccactagc ccggggggta cgcagacccc acactcagca gaaggagact 1800[0236] caggactgct gaaggcacgg gagctgcccc cagtggacac cagtgaaccc cagtcagcct 1860[0237] ggacccctaa cacagaccat gaggagacgc tgggaacttg tgggactcac ctgactcaaa 1920[0238] gatg 1924[0239] <210>5

[0240] <211>1536

[0241] <212>DNA

[0242] <213>人

[0243] <400>5

[0244] gtgacgcgag gctctgcgga gaccaggagt cagactgtag gacgacctcg ggtcccacgt 60[0245] gtccccggta ctcgccggcc ggagcccccg gcttcccggg gccgggggac cttagcggca 120[0246] cccacacaca gcctactttc caagcggagc catgtctggt aacggcaatg cggctgcaac 180[0247] ggcggaagaa aacagcccaa agatgagagt gattcgcgtg ggtacccgca agagccagct 240[0248] tgctcgcata cagacggaca gtgtggtggc aacattgaaa gcctcgtacc ctggcctgca 300[0249] gtttgaaatc attgctatgt ccaccacagg ggacaagatt cttgatactg cactctctaa 360[0250] gattggagag aaaagcctgt ttaccaagga gcttgaacat gccctggaga agaatgaagt 420[0251] ggacctggtt gttcactcct tgaaggacct gcccactgtg cttcctcctg gcttcaccat 480[0252] cggagccatc tgcaagcggg aaaaccctca tgatgctgtt gtctttcacc caaaatttgt 540[0253] tgggaagacc ctagaaaccc tgccagagaa gagtgtggtg ggaaccagct ccctgcgaag 600[0254] agcagcccag ctgcagagaa agttcccgca tctggagttc aggagtattc ggggaaacct 660[0255] caacacccgg cttcggaagc tggacgagca gcaggagttc agtgccatca tcctggcaac 720[0256] agctggcctg cagcgcatgg gctggcacaa ccgggtgggg cagatcctgc accctgagga 780[0257] atgcatgtat gctgtgggcc agggggcctt gggcgtggaa gtgcgagcca aggaccagga 840[0258] catcttggat ctggtgggtg tgctgcacga tcccgagact ctgcttcgct gcatcgctga 900[0259] aagggccttc ctgaggcacc tggaaggagg ctgcagtgtg ccagtagccg tgcatacagc 960[0260] tatgaaggat gggcaactgt acctgactgg aggagtctgg agtctagacg gctcagatag 1020[0261] catacaagag accatgcagg ctaccatcca tgtccctgcc cagcatgaag atggccctga 1080[0262] ggatgaccca cagttggtag gcatcactgc tcgtaacatt ccacgagggc cccagttggc 1140[0263] tgcccagaac ttgggcatca gcctggccaa cttgttgctg agcaaaggag ccaaaaacat 1200[0264] cctggatgtt gcacggcagc ttaacgatgc ccattaactg gtttgtgggg cacagatgcc 1260[0265] tgggttgctg ctgtccagtg cctacatccc gggcctcagt gccccattct cactgctatc 1320[0266] tggggagtga ttaccccggg agactgaact gcagggttca agccttccag ggatttgcct 1380[0267] caccttgggg ccttgatgac tgccttgcct cctcagtatg tgggggcttc atctctttag 1440[0268] agaagtccaa gcaacagcct ttgaatgtaa ccaatcctac taataaacca gttctgaagg 1500[0269] taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa 1536[0270] <210>6

[0271] <211>3345

[0272] <212>DNA

[0273] <213>人

[0274] <400>6

[0275] gaattccgtc tcgaccactg aatggaagaa aaggactttt aaccaccatt ttgtgactta 60[0276] cagaaaggaa tttgaataaa gaaaactatg atacttcagg cccatcttca ctccctgtgt 120[0277] cttcttatgc tttatttggc aactggatat ggccaagagg ggaagtttag tggacccctg 180[0278] aaacccatga cattttctat ttatgaaggc caagaaccga gtcaaattat attccagttt 240[0279] aaggccaatc ctcctgctgt gacttttgaa ctaactgggg agacagacaa catatttgtg 300[0280] atagaacggg agggacttct gtattacaac agagccttgg acagggaaac aagatctact 360[0281] cacaatctcc aggttgcagc cctggacgct aatggaatta tagtggaggg tccagtccct 420[0282] atcaccatag aagtgaagga catcaacgac aatcgaccca cgtttctcca gtcaaagtac 480[0283] gaaggctcag taaggcagaa ctctcgccca ggaaagccct tcttgtatgt caatgccaca 540[0284] gacctggatg atccggccac tcccaatggc cagctttatt accagattgt catccagctt 600[0285] cccatgatca acaatgtcat gtactttcag atcaacaaca aaacgggagc catctctctt 660[0286] acccgagagg gatctcagga attgaatcct gctaagaatc cttcctataa tctggtgatc 720[0287] tcagtgaagg acatgggagg ccagagtgag aattccttca gtgataccac atctgtggat 780[0288] atcatagtga cagagaatat ttggaaagca ccaaaacctg tggagatggt ggaaaactca 840[0289] actgatcctc accccatcaa aatcactcag gtgcggtgga atgatcccgg tgcacaatat 900[0290] tccttagttg acaaagagaa gctgccaaga ttcccatttt caattgacca ggaaggagat 960[0291] atttacgtga ctcagccctt ggaccgagaa gaaaaggatg catatgtttt ttatgcagtt 1020[0292] gcaaaggatg agtacggaaa accactttca tatccgctgg aaattcatgt aaaagttaaa 1080[0293] gatattaatg ataatccacc tacatgtccg tcaccagtaa ccgtatttga ggtccaggag 1140[0294] aatgaacgac tgggtaacag tatcgggacc cttactgcac atgacaggga tgaagaaaat 1200[0295] actgccaaca gttttctaaa ctacaggatt gtggagcaaa ctcccaaact tcccatggat 1260[0296] ggactcttcc taatccaaac ctatgctgga atgttacagt tagctaaaca gtccttgaag 1320[0297] aagcaagata ctcctcagta caacttaacg atagaggtgt ctgacaaaga tttcaagacc 1380[0298] ctttgttttg tgcaaatcaa cgttattgat atcaatgatc agatccccat ctttgaaaaa 1440[0299] tcagattatg gaaacctgac tcttgctgaa gacacaaaca ttgggtccac catcttaacc 1500[0300] atccaggcca ctgatgctga tgagccattt actgggagtt ctaaaattct gtatcatatc 1560[0301] ataaagggag acagtgaggg acgcctgggg gttgacacag atccccatac caacaccgga 1620[0302] tatgtcataa ttaaaaagcc tcttgatttt gaaacagcag ctgtttccaa cattgtgttc 1680[0303] aaagcagaaa atcctgagcc tctagtgttt ggtgtgaagt acaatgcaag ttcttttgcc 1740[0304] aagttcacgc ttattgtgac agatgtgaat gaagcacctc aattttccca acacgtattc 1800[0305] caagcgaaag tcagtgagga tgtagctata ggcactaaag tgggcaatgt gactgccaag 1860[0306] gatccagaag gtctggacat aagctattca ctgaggggag acacaagagg ttggcttaaa 1920[0307] attgaccacg tgactggtga gatctttagt gtggctccat tggacagaga agccggaagt 1980[0308] ccatatcggg tacaagtggt ggccacagaa gtaggggggt cttccttaag ctctgtgtca 2040[0309] gagttccacc tgatccttat ggatgtgaat gacaaccctc ccaggctagc caaggactac 2100[0310] acgggcttgt tcttctgcca tcccctcagt gcacctggaa gtctcatttt cgaggctact 2160[0311] gatgatgatc agcacttatt tcggggtccc cattttacat tttccctcgg cagtggaagc 2220[0312] ttacaaaacg actgggaagt ttccaaaatc aatggtactc atgcccgact gtctaccagg 2280[0313] cacacagact ttgaggagag ggcgtatgtc gtcttgatcc gcatcaatga tgggggtcgg 2340[0314] ccacccttgg aaggcattgt ttctttacca gttacattct gcagttgtgt ggaaggaagt 2400[0315] tgtttccggc cagcaggtca ccagactggg atacccactg tgggcatggc agttggtata 2460[0316] ctgctgacca cccttctggt gattggtata attttagcag ttgtgtttat ccgcataaag 2520[0317] aaggataaag gcaaagataa tgttgaaagt gctcaagcat ctgaagtcaa acctctgaga 2580[0318] agctgaattt gaaaaggaat gtttgaattt atatagcaag tgctatttca gcaacaacca 2640[0319] tctcatccta ttacttttca tctaacgtgc attataattt tttaaacaga tattccctct 2700[0320] tgtcctttaa tatttgctaa atatttcttt tttgaggtgg agtcttgctc tgtcgcccag 2760[0321] gctggagtac agtggtgtga tcccagctca ctgcaacctc cgcctcctgg gttcacatga 2820[0322] ttctcctgcc tcagcttcct aagtagctgg gtttacaggc acccaccacc atgcccagct 2880[0323] aatttttgta tttttaatag agacggggtt tcgccatttg gccaggctgg tcttgaactc 2940[0324] ctgacgtcaa gtgatctgcc tgccttggtc tcccaataca ggcatgaacc actgcaccca 3000[0325] cctacttaga tatttcatgt gctatagaca ttagagagat ttttcatttt tccatgacat 3060[0326] ttttcctctc tgcaaatggc ttagctactt gtgtttttcc cttttggggc aagacagact 3120[0327] cattaaatat tctgtacatt ttttctttat caaggagata tatcagtgtt gtctcataga 3180[0328] actgcctgga ttccatttat gttttttctg attccatcct gtgtcccctt catccttgac 3240[0329] tcctttggta tttcactgaa tttcaaacat ttgtcagaga agaaaaaagt gaggactcag 3300[0330] gaaaaataaa taaataaaag aacagccttt tgcggccgcg aattc 3345[0331] <210>7

[0332] <211>1924

[0333] <212>DNA

[0334] <213>人

[0335] <400>7

[0336] ccatgacgcc cgccctcaca gccctgctct gccttgggct gagtctgggc cccaggaccc 60[0337] gcatgcaggc agggcccttc cccaaaccca ccctctgggc tgagccaggc tctgtgatca 120[0338] gctgggggag ccccgtgacc atctggtgtc aggggagcct ggaggcccag gagtaccaac 180[0339] tggataaaga gggaagccca gagccctggg acagaaataa cccactggaa cccaagaaca 240[0340] aggccagatt ctccatccca tccatgacac agcaccatgc agggagatac cgctgccact 300[0341] attacagctc tgcaggctgg tcagagccca gcgaccccct ggagctggtg atgacaggat 360[0342] tctacaacaa acccaccctc tcagccctgc ccagccctgt ggtggcctca ggggggaata 420[0343] tgaccctccg atgtggctca cagaagggat atcaccattt tgttctgatg aaggaaggag 480[0344] aacaccagct cccccggacc ctggactcac agcagctcca cagtgggggg ttccaggccc 540[0345] tgttccctgt gggccccgtg acccccagcc acaggcgtgt ctaggaagcc ctccctcctg 600[0346] accctgcagg gccctgtcct ggcccctggg cagagcctga ccctccagtg tggctctgat 660[0347] gtcggctacg acagatttgt tctgtataag gagggggaac gtgacttcct ccagcgccct 720[0348] ggccagcagc cccaggctgg gctctcccag gccaacttca ccctgggccc tgtgagccgc 780[0349] tcctacgggg gccagtacag gtgctatggt gcacacaacc tctcctccga gtggtcggcc 840[0350] cccagtgacc ccctggacat cctgatcaca ggacagatct atgacaccgt ctccctgtca 900[0351] gcacagccgg gccccacagt ggcctcagga gagaacatga ccctgctgtg tcagtcacgg 960[0352] gggtattttg acactttcct tctgaccaaa gaaggggcag cccatccccc actgcgtctg 1020[0353] agatcaatgt acggagctca taagtaccag gctgaattcc ccatgagtcc tgtgacctca 1080[0354] gcccacgcgg ggacctacag gtgctacggc tcacgcagct ccaaccccca cctgctgtct 1140[0355] ttccccagtg agcccctgga actcatggtc tcaggacact ctggaggctc cagcctccca 1200[0356] cccacagggc cgccctccac acctggtctg ggaagatacc tggaggtttt gattggggtc 1260[0357] tcggtggcct tcgtcctgct gctcttcctc ctcctcttcc tcctcctccg acgtcagcgt 1320[0358] cacagcaaac acaggacatc tgaccagaga aagactgatt tccagcgtcc tgcaggggct 1380[0359] gcggagacag agcccaagga caggggcctg ctgaggaggt ccagcccagc tgctgacgtc 1440[0360] caggaagaaa acctctagcc cacacgatga agacccccag gcagtgacgt atgccccggt 1500[0361] gaaacactcc agtcctagga gagaaatggc ctctcctccc tcctcactgt ctggggaatt 1560[0362] cctggacaca aaggacagac aggtggaaga ggacaggcag atggacactg aggctgctgc 1620[0363] atctgaagcc tcccaggatg tgacctacgc ccagctgcac agcttgaccc ttagacggaa 1680[0364] ggcaactgag cctcctccat cccaggaagg ggaacctcca gctgagccca gcatctacgc 1740[0365] cactctggcc atccactagc ccggggggta cgcagacccc acactcagca gaaggagact 1800[0366] caggactgct gaaggcacgg gagctgcccc cagtggacac cagtgaaccc cagtcagcct 1860[0367] ggacccctaa cacagaccat gaggagacgc tgggaacttg tgggactcac ctgactcaaa 1920[0368] gatg 1924[0369] <210>8

[0370] <211>1775

[0371] <212>DNA

[0372] <213>人

[0373] <400>8

[0374] agcggccggg gcgagccagc gagagggcgc gagcggcggc gctgcctgca gcctgcagcc 60[0375] tgcagcctcc ggccggccgg cgagccagtg cgcgtgcgcg gcggcggcct ccgcagcgac 120[0376] cggggagcgg actgaccggc gggagggcta gcgagccagc ggtgtgaggc gcgaggcgag 180[0377] gccgagccgc gagcgacatg ggggaccggg agcagctgct gcagcgggcg cggctggccg 240[0378] agcaggcgga gcgctacgac gacatggcct ccgctatgaa ggcggtgaca gagctgaatg 300[0379] aacctctctc caatgaagat cgaaatctcc tctctgtggc ctacaagaat gtggttggtg 360[0380] ccaggcgatc ttcctggagg gtcattagca gcattgagca gaaaaccatg gctgatggaa 420[0381] acgaaaagaa attggagaaa gttaaagctt accgggagaa gattgagaag gagctggaga 480[0382] cagtttgcaa tgatgtcctg tctctgcttg acaagttcct gatcaagaac tgcaatgatt 540[0383] tccagtatga gagcaaggtg ttttacctga aaatgaaggg tgattactac cgctacttag 600[0384] cagaggtcgc ttctggggag aagaaaaaca gtgtggtcga agcttctgaa gctgcctaca 660[0385] aggaagcctt tgaaatcagc aaagagcaga tgcaacccac gcatcccatc cggctgggcc 720[0386] tggccctcaa cttctccgtg ttctactatg agatccagaa tgcacctgag caagcctgcc 780[0387] tcttagccaa acaagccttc gatgatgcca tagctgagct ggacacacta aacgaggatt 840[0388] cctataagga ctccacgctg atcatgcagt tgctgcgaga caacctcacc ctctggacga 900[0389] gcgaccagca ggatgaagaa gcaggagaag gcaactgaag atccttcagg tcccctggcc 960[0390] cttccttcac ccaccacccc catcatcacc gattcttcct tgccacaatc actaaatatc 1020[0391] tagtgctaaa cctatctgta ttggcagcac agctactcag atctgcactc ctgtctcttg 1080[0392] ggaagcagtt tcagataaat catgggcatt gctggactga tggttgcttt gagcccacag 1140[0393] gagctccctt tttgaattgt gtggagaagt gtgttctgat gaggcatttt actatgcctg 1200[0394] ttgatctatg ggaaatctag gcgaaagtaa tggggaagat tagaaagaat tagccaacca 1260[0395] ggctacagtt gatatttaaa agatccattt aaaacaagct gatagtgttt cgttaagcag 1320[0396] tacatcttgt gcatgcaaaa atgaattcac ccctcccacc tctttcttca attaatggaa 1380[0397] aactgttaag ggaagctgat acagagagac aacttgctcc tttccatcag ctttataata 1440[0398] aactgtttaa cgtgaggttt cagtagctcc ttggttttgc ctctttaaat tatgacgtgc 1500[0399] acaaaccttc ttttcaatgc aatgcatctg aaagttttga tacttgtaac tttttttttt 1560[0400] ttttggttgc aattgtttaa gaatcatgga tttatttttt gtaactcttt ggctattgtc 1620[0401] cttgtgtatc ctgacagcgc catgtgtgtc agcccatgtc aatcaagatg ggtgattatg 1680[0402] aaatgccaga cttctaaaat aaatgttttg gaattcaatg ggtaaataaa tgctgctttg 1740[0403] gggatattaa aaaaaaaaaa aaaaaaaaaa aaaaa 1775[0404] <210>9

[0405] <211>1724

[0406] <212>DNA

[0407] <213>人

[0408] <400>9

[0409] ctttttggag acagattcgc agtggtcgct tcttctcctt ggatttgtta aggattccaa 60[0410] gtaactctta tttggagaga agacgatctg cacttcgcat tttggcattg acatttaatt 120[0411] ttagggtcct ttatatagaa gggagagtag ctacatgaat gtgtaagatc ttggaggaag 180[0412] acagcagaga gagagagaga gatcagagat cccagggtta aaagttggag aaatttcaca 240[0413] gtacatcatc caaaagagga gtccatgatg gaggcagagg taaacttgga gaggacagga 300[0414] agatgtcacc caagcgcata gctaaaagaa ggtccccccc agcagatgcc atccccaaaa 360[0415] gcaagaaggt gaaggtctca cacaggtccc acagcacaga acccggcttg gtgctgacac 420[0416] taggccaggg cgacgtgggc cagctggggc tgggtgagaa tgtgatggag aggaagaagc 480[0417] cggccctggt atccattccg gaggatgttg tgcaggctga ggctgggggc atgcacaccg 540[0418] tgtgtctaag caaaagtggc caggtctatt ccttcggctg caatgatgag ggtgccctgg 600[0419] gaagggacac atcagtggag ggctcggaga tggtccctgg gaaagtggag ctgcaagaga 660[0420] aggtggtaca ggtgtcagca ggagacagtc acacagcagc cctcaccgat gatggccgtg 720[0421] tcttcctctg gggctccttc cgggacaata acggtgtgat tggactgttg gagcccatga 780[0422] agaagagcat ggtgcctgtg caggtgcagc tggatgtgcc tgtggtaaag gtggcctcag 840[0423] gaaacgacca cttggtgatg ctgacagctg atggtgacct ctacaccttg ggctgcgggg 900[0424] aacagggcca gctaggccgt gtgcctgagt tatttgccaa ccgtggtggc cggcaaggcc 960[0425] tcgaacgact cctggtcccc aagtgtgtga tgctgaaatc caggggaagc cggggccacg 1020[0426] tgagattcca ggatgccttt tgtggtgcct atttcacctt tgccatctcc catgagggcc 1080[0427] acgtgtacgg cttcggcctc tccaactacc atcagcttgg aactccgggc acagaatctt 1140[0428] gcttcatacc ccagaaccta acatccttca agaattccac caagtcctgg gtgggcttct 1200[0429] ctggtggcca gcaccataca gtctgcatgg attcggaagg aaaagcatac agcctgggcc 1260[0430] gggctgagta tgggcggctg ggccttggag agggtgctga ggagaagagc atacccaccc 1320[0431] tcatctccag gctgcctgct gtctcctcgg tggcttgtgg ggcctctgtg gggtatgctg 1380[0432] tgaccaagga tggtcgtgtt ttcgcctggg gcatgggcac caactaccag ctgggcacag 1440[0433] ggcaggatga ggacgcctgg agccctgtgg agatgatggg caaacagctg gagaaccgtg 1500[0434] tggtcttatc tgtgtccagc gggggccagc atacagtctt attagtcaag gacaaagaac 1560[0435] agagctgatg aagcctctga gggcctggct tctgtcctgc acaacctccc tcacagaaca 1620[0436] gggaagcagt gacagctgca gatggcagcg ggcctctccc cagccctgag cactgtgtca 1680[0437] gttcctgcct tttctcatca gcagaacaga atccttttcc tctt 1724[0438] <210>10

[0439] <211>1622

[0440] <212>DNA

[0441] <213>人

[0442] <400>10

[0443] cgttggcgtt tacgtgtgga agagcggaag agttttgctt ttcgtgcgcg ccttcgaaaa 60[0444] ctgcctgccg ctgtctgagg agtccacccg aaacctcccc tcctccgccg gcagccccgc 120[0445] gctgagctcg ccgacccaag ccagcgtggg cgaggtggga agtgcgcccg acccgcgcct 180[0446] ggagctgcgc ccccgagtgc ccatggctac aagggtgctg agcatgagcg cccgcctggg 240[0447] acccgtgccc cagccgccgg cgccgcagga cgagccggtg ttcgcgcagc tcaagccggt 300[0448] gctgggcgcc gcgaatccgg cccgcgacgc ggcgctcttc cccggcgagg agctgaagca 360[0449] cgcgcaccac cgcccgcagg cgcagcccgc gcccgcgcag gccccgcagc cggcccagcc 420[0450] gcccgccacc ggcccgcggc tgcctccaga ggacctggtc cagacaagat gtgaaatgga 480[0451] gaagtatctg acacctcagc ttcctccagt tcctataatt ccagagcata aaaagtatag 540[0452] acgagacagt gcctcagtcg tagaccagtt cttcactgac actgaagggt taccttacag 600[0453] tatcaacatg aacgtcttcc tccctgacat cactcacctg agaactggcc tctacaaatc 660[0454] ccagagaccg tgcgtaacac acatcaagac agaacctgtt gccattttca gccaccagag 720[0455] tgaaacgact gcccctcctc cggccccgac ccaggccctc cctgagttca ccagtatatt 780[0456] cagctcacac cagaccgcag ctccagaggt gaacaatatt ttcatcaaac aagaacttcc 840[0457] tacaccagat cttcatcttt ctgtccctac ccagcagggc cacctgtacc agctactgaa 900[0458] tacaccggat ctagatatgc ccagttctac aaatcagaca gcagcaatgg acactcttaa 960[0459] tgtttctatg tcagctgcca tggcaggcct taacacacac acctctgctg ttccgcagac 1020[0460] tgcagtgaaa caattccagg gcatgccccc ttgcacatac acaatgccaa gtcagtttct 1080[0461] tccacaacag gccacttact ttcccccgtc accaccaagc tcagagcctg gaagtccaga 1140[0462] tagacaagca gagatgctcc agaatttaac cccacctcca tcctatgctg ctacaattgc 1200[0463] ttctaaactg gcaattcaca atccaaattt acccaccacc ctgccagtta actcacaaaa 1260[0464] catccaacct gtcagataca atagaaggag taaccccgat ttggagaaac gacgcatcca 1320[0465] ctactgcgat taccctggtt gcacaaaagt ttataccaag tcttctcatt taaaagctca 1380[0466] cctgaggact cacactggtg aaaagccata caagtgtacc tgggaaggct gcgactggag 1440[0467] gttcgcgcga tcggatgagc tgacccgcca ctaccggaag cacacaggcg ccaagccctt 1500[0468] ccagtgcggg gtgtgcaacc gcagcttctc gcgctctgac cacctggccc tgcatatgaa 1560[0469] gaggcaccag aactgagcac tgcccgtgtg acccgttcca ggtcccctgg gctccctcaa 1620[0470] at 1622[0471] <210>11

[0472] <211>1221

[0473] <212>DNA

[0474] <213>人

[0475] <400>11

[0476] cgcaggctgg aaggaagacg aacctacgaa gcagagatct gaagacagca tgtacacagc 60[0477] cattccccag agtggctctc cattcccagg ctcagtgcag gatccaggcc tgcatgtgtg 120[0478] gcgggtggag aagctgaagc cggtgcctgt ggcgcaagag aaccagggcg tcttcttctc 180[0479] gggggactcc tacctagtgc tgcacaatgg cccagaagag gtttcccatc tgcacctgtg 240[0480] gataggccag cagtcatccc gggatgagca gggggcctgt gccgtgctgg ctgtgcacct 300[0481] caacacgctg ctgggagagc ggcctgtgca gcaccgcgag gtgcagggca atgagtctga 360[0482] cctcttcatg agctacttcc cacggggcct caagtaccag gaaggtggtg tggagtcagc 420[0483] atttcacaag acctccacag gagccccagc tgccatcaag aaactctacc aggtgaaggg 480[0484] gaagaagaac atccgtgcca ccgagcgggc actgaactgg gacagcttca acactgggga 540[0485] ctgcttcatc ctggacctgg gccagaacat cttcgcctgg tgtggtggaa agtccaacat 600[0486] cctggaacgc aacaaggcga gggacctggc cctggccatc cgggacagtg agcgacaggg 660[0487] caaggcccag gtggagattg tcactgatgg ggaggagcct gctgagatga tccaggtcct 720[0488] gggccccaag cctgctctga aggagggcaa ccctgaggaa gacctcacag ctgacaaggc 780[0489] aaatgcccag gccgcagctc tgtataaggt ctctgatgcc actggacaga tgaacctgac 840[0490] caaggtggct gactccagcc cctttgccct tgaactgctg atatctgatg actgctttgt 900[0491] gctggacaac gggctctgtg gcaagatcta tatctggaag gggcgaaaag cgaatgagaa 960[0492] ggagcggcag gcagccctgc aggtggccga gggcttcatc tcgcgcatgc agtacgcccc 1020[0493] gaacactcag gtggagattc tgcctcaggg ccgtgagagt cccatcttca agcaattttt 1080[0494] caaggactgg aaatgagggt gggcgtcttc ctgccccatg ctcccctgcc ccccaccacc 1140[0495] tgcctgcttg cttctctggc tgcctggtca gtgcagaggt gccccctgca gatgttcaat 1200[0496] aaaggagaca agtgctttcc c 1221[0497] <210>12

[0498] <211>1460

[0499] <212>DNA

[0500] <213>人

[0501] <400>12

[0502] accccatctt catctggcct tgactctgcc cttgaggggc ctaggggtgc agccagcctg 60[0503] ctccgagctc ccctgcagat ggaggaggcc atcctggtcc cctgcgtgct ggggctcctg 120[0504] ctgctgccca tcctggccat gttgatggca ctgtgtgtgc actgccacag actgccaggc 180[0505] tcctacgaca gcacatcctc agatagtttg tatccaaggg gcatccagtt caaacggcct 240[0506] cacacggttg ccccctggcc acctgcctac ccacctgtca cctcctaccc acccctgagc 300[0507] cagccagacc tgctccccat cccaagatcc ccgcagcccc ttgggggctc ccaccggacg 360[0508] ccatcttccc ggcgggattc tgatggtgcc aacagtgtgg cgagctacga gaacgagggt 420[0509] gcgtctggga tccgaggtgc ccaggctggg tggggagtct ggggtccgtc ctggactagg 480[0510] ctgacccctg tgtcgttacc cccagaacca gcctgtgagg atgcagatga ggatgaggac 540[0511] gactatcaca acccaggcta cctggtggtg cttcctgaca gcaccccggc cactagcact 600[0512] gctgccccat cagctcctgc actcagcacc cctggcatcc gagacagtgc cttctccatg 660[0513] gagtccattg atgattacgt gaacgttccg gagagcgggg agagcgcaga agcgtctctg 720[0514] gatggcagcc gggagtatgt gaatgtgtcc caggaactgc atcctggagc ggctaagact 780[0515] gagcctgccg ccctgagttc ccaggaggca gaggaagtgg aggaagaggg ggctccagat 840[0516] tacgagaatc tgcaggagct gaactgaggg cctgtggagg ccgagtctgt cctggaacca 900[0517] ggcttgcctg ggacggctga gctgggcagc tggaagtggc tctggggtcc tcacatggcg 960[0518] tcctgccctt gctccagcct gacaacagcc tgagaaatcc ccccgtaact tattatcact 1020[0519] ttggggttcg gcctgtgtcc cccgaacgct ctgcaccttc tgacgcagcc tgagaatgac 1080[0520] ctgccctggc cccagcccta ctctgtgtaa tagaataaag gcctgcgtgt gtctgtgttg 1140[0521] agcgtgcgtc tgtgtgtgcc tgtgtgcgag tctgagtcag agatttggag atgtctctgt 1200[0522] gtgtttgtgt gtatctgtgg gtctccatcc tccatggggg ctcagccagg tgctgtgaca 1260[0523] ccccccttct gaatgaagcc ttctgacctg ggctggcact gctgggggtg aggacacatt 1320[0524] gccccatgag acagtcccag aacacggcag ctgctggctg tgacaatggt ttcaccatcc 1380[0525] ttagaccaag ggatgggacc tgatgacctg ggaggactct tttagttctt acctcttgtg 1440[0526] gttctcaata aaacagaacg 1460[0527] <210>13

[0528] <211>1403

[0529] <212>DNA

[0530] <213>人

[0531] <400>13

[0532] gcttccgctt tggggtggtg gtgccacccg ccgtggccgg cgcccggccg gagctgctgg 60[0533] tggtggggtc gcggcccgag ctggggcgtt gggagccgcg cggtgccgtc cgcctgaggc 120[0534] cggccggcac cgcggcgggc gacggggccc tggcgctgca ggagccgggc ctgtggctcg 180[0535] gggaggtgga gctggcggcc gaggaggcgg cgcaggacgg ggcggagccg ggccgcgtgg 240[0536] acacgttctg gtacaagttc ctgaagcggg agccgggagg agagctctcc tgggaaggca 300[0537] atggacctca tcatgaccgt tgctgtactt acaatgaaaa caacttggtg gatggtgtgt 360[0538] attgtctccc aataggacac tggattgagg ccactgggca caccaatgaa atgaagcaca 420[0539] caacagactt ctattttaat attgcaggcc accaagccat gcattattca aggccgagta 480[0540] cagatgctgc cccaggcggt gtgcctgctg catgcgctgc tggagaaggg acacatcgtg 540[0541] tacgtgcact gcaacgctgg ggtgggccgc tccaccgcgg ctgtctgcgg ctggctccag 600[0542] tatgtgatgg gctggaatct gaggaaggtg cagtatttcc tcatggccaa gaggccggct 660[0543] gtctacattg acgaagaggc cttggcccgg gcacaagaag attttttcca gaaatttggg 720[0544] aaggttcgtt cttctgtgtg tagcctgtag ctggtcagcc tgcttctgcc ccctcctgat 780[0545] ttccctaagg agcctgggat gatgttggtc aaatgaccta gaaacaagga ttctacctga 840[0546] actgaaagga ctgtgtgacc tcccccaagc caaccacttt cacctgggat gactttcgat 900[0547] tatgctttgt tttggggctg tatttttgaa atactctaca agaaagctgt ggctcaacac 960[0548] atgagaagaa gcacgaagca gttaggctgt acatcagaca gaagggtaat gcgtgcagtt 1020[0549] cctgctgcct gcaggcagac gaggcctttg ctttacagca ctgtatgtgt tgcacgatgg 1080[0550] atccgtgaca gcactttcct gttgcactga aactcttggc catgtagagg aaaagatatg 1140[0551] gagttatgtg gatttcatca ctagtatgtg tgcgtgagct ggtcagttgc caaaggagga 1200[0552] aataaggtta gaagcctgaa ccgttacaaa agaagagctc actatggtca aaaagtgatg 1260[0553] gctttcagga cttgtttttt atcctgcctc acagttgtta aagtctgttc caaggcatca 1320[0554] ccttccttct ctacccaaca accctgtgta acaactaaag tagaattatc tcaaaaaa 1380[0555] aaaaaaaaaa aaaaaaaaaa aaa 1403[0556] <210>14

[0557] <211>3463

[0558] <212>DNA

[0559] <213>人

[0560] <400>14

[0561] atggctgagc cgactagtga tttcgagact cctatcgggt ggcatgcgtc tcccgagctg 60[0562] actcccacgt tagggcccct gagcgacact gccccgccgc gggacaggtg gatgttctgg 120[0563] gcaatgctgc cgccaccgcc accaccactt acgtcctcgc ttcccgcagc cgggtcaaag 180[0564] ccttcctctg agtcgcagcc ccccatggag gcccagtctc tccccggggc tccgcccccc 240[0565] ttcgacgccc agattcttcc cggggcgcaa ccccccttcg acgcccagtc tccccttgat 300[0566] tctcagcctc aacccagcgg ccagccttgg aatttccatg cttccacatc gtggtattgg 360[0567] agacagtctt ctgataggtt tcctcggcat cagaagtcct tcaaccctgc agttaaaaat 420[0568] tcttattatc cacgaaagta tgatgcaaaa ttcacagact tcagcttacc tcccagtaga 480[0569] aaacagaaaa aaaagaaaag aaaggaacca gtttttcact ttttttgtga tacctgtgat 540[0570] cgtggtttta aaaatcaaga aaagtatgac aaacacatgt ctgaacatac aaaatgccct 600[0571] gaattagatt gctcttttac tgcacacgag aagattgtcc agttccattg gagaaatatg 660[0572] catgctcctg gcatgaagaa gatcaagtta gacactccag aggaaattgc acggtggagg 720[0573] gaagaaagaa ggaaaaacta tccaactctg gccaatattg aaaggaagaa gaagttaaaa 780[0574] cttgaaaagg agaagagagg agcagtattg acaacaacac aatatggcaa gatgaagggg 840[0575] atgtccagac attcacaaat ggcaaagatc agaagtcctg gcaagaatca caaatggaaa 900[0576] aacgacaatt ctagacagag agcagtcact ggatcaggca gtcacttgtg tgatttgaag 960[0577] ctagaaggtc caccggaggc aaatgcagat cctcttggtg ttttgataaa cagtgattct 1020[0578] gagtctgata aggaggagaa accacaacat tctgtgatac ccaaggaagt gacaccagcc 1080[0579] ctatgctcac taatgagtag ctatggcagt ctttcagggt cagagagtga gccagaagaa 1140[0580] actcccatca agactgaagc agacgttttg gcagaaaacc aggttcttga tagcagtgct 1200[0581] cctaagagtc caagtcaaga tgttaaagca actgttagaa atttttcaga agccaagagt 1260[0582] gagaaccgaa agaaaagctt tgaaaaaaca aaccctaaga ggaaaaaaga ttatcacaac 1320[0583] tatcaaacgt tattcgaacc aagaacacac catccatatc tcttggaaat gcttctagct 1380[0584] ccggacattc gacatgaaag aaatgtgatt ttgcagtgtg ttcggtacat cattaaaaaa 1440[0585] gacttttttg gactggatac taattctgcg aaaagtaaag atgtataggc atctggtgtt 1500[0586] tcagcataca taactgaagc atgtgaaaca gtatcatcct cgttagtaga ggaaaaccaa 1560[0587] aacccttttt tccgtcaaaa ttggatttgt aattaaattg taagcctcgt aggatgtatg 1620[0588] ttggaatttt aagtctttcc tttggttcta tgcaaataaa aaaataactg attttttaag 1680[0589] actgtgtctg tattgttggg attgaatcta gtatttgctg ggagaatttt ttctttgtat 1740[0590] ttattttaat gtattgttct catgtaagaa tgactgatgt tgtgttagtt aagaattgaa 1800[0591] gataggttta gcagtaaaga agaaagcttt taaaaggatt gattcagcta agcaaagttg 1860[0592] ggcagagaaa tacagccatt ttgtttttaa tgcagaaaag gaagatgttc tgtagcaagg 1920[0593] gggaatattt taaaaataaa ccagatcaaa ttaatacaat cagaaggttt cgaaatgtaa 1980[0594] atattcctta tttaagacat gtttaaattc acctactagc acgacttaca tagctcaaat 2040[0595] attgaatgtt taaaatatta atacagatgg ggcctcttta tgtttagata aaattgaagt 2100[0596] acttaattga agctttttaa aaattgtaaa gtaaatgaaa gctattgaga tctttttgtc 2160[0597] tcctataata ccagggaatt tgagcttgtg ttctagtcat tgtactagct gtagctattg 2220[0598] gtctgtcctt ttgacataca gctaaaaggg actaaatttg taaaaaatta gtttgttata 2280[0599] gttgaagatt aacttttcct aacattgtga ttattgaagt tcatgaatct tgctgtcaag 2340[0600] gaagaaaggt aagaaagctg atagctcctc catgttggta aaatcctctc cagaatcttg 2400[0601] gaacacctgg catgtgaccc tagtgacgtc acagacctga gatgaagatt catgtttagc 2460[0602] cagtgttttc cagccttgta cccaccatac agatctgttt attctgtttc accctactcc 2520[0603] tccagtgagc cccatatttt gggaaattat ctgccttata cattaactaa ttcaattcat 2580[0604] gtaacactgt tgagtgctta ctctttgtac ctctattgtg cctatattaa aggtatacaa 2640[0605] ataaataagg ccatgtctga cttcaaggaa ctcagtttaa ttttgatata ttcaaagatg 2700[0606] tgattcccaa ccaactcagg atgaagtaac tagtgttaca actgagttga tattctaaaa 2760[0607] tataacccag tttgtacttt tattactagt tagcatacac attttatggc ttatgggtta 2820[0608] ataaatgaat tcatggactc ctggactact ttcattgatg accatatctc cagggatgtt 2880[0609] gttgatcccc acactgcctt aaggtatatt atagaaacag ttttattttc catttttctt 2940[0610] gtttcctgat aataaatgta tttaggactg aaaatactcc tgagtactcc cctggctgta 3000[0611] tgtctgacag tctttagcta tggtgactat tgtttatttt taatgggtat ttcagattcc 3060[0612] aagtgtattt aaaatttcta aggagatata atatagcctg tatggtttct actttatgga 3120[0613] attatatggt caatatttgt aaatattcta tgagttttgg gtgggtagag gggtgctttg 3180[0614] cctgttttgg gtacaggttt ttttggattt agcttgttaa ttgttcaaac tttctgcctt 3240[0615] ctacattcct atcttattgt tcgtttaatc agtttctgaa atgtaagcat tacatgacta 3300[0616] ttggtgagtt gtgcctttta taactgaaat actttacttt ttctcatatc ctctataatt 3360[0617] gacttctatt ttccttaatc aaaccagctc tgggaaattt aatacattta tattaattga 3420[0618] gattattaaa acatttggac tattaaaaaa aaaaaaaaaa aaa 3463[0619] <210>15

[0620] <211>5115

[0621] <212>DNA

[0622] <213>人

[0623] <400>15

[0624] gaattccggg agcgggcggg ctgcgaggcc gcggggcatg cgggaggcgg aggggtggga 60[0625] ccgggtggct gcgcccattc cacacccgcc gaaagcggac actgtcagct gaatcactcc 120[0626] ccttttagga ggagggaggg ggaaaaggtg tctagctaat ttctgcttaa aaaagcacag 180[0627] gagatcgcgg gtcagctttg cagtcgctgc cttctcgcgc ctgaccatgc acccctgcat 240[0628] cttcctgctg ggcacaggcg agcgctttat ttctggagct gagggctaaa acttttttca 300[0629] cttttcttct cctcaacatc tgaatcatgc catgtgccca gaggagctgg cttgcaaacc 360[0630] tttccgtggt ggctcagctc cttaactttg gggcgctttg ctatgggaga cagcctcagc 420[0631] caggcccggt tcgcttcccg gacaggaggc aagagcattt tatcaagggc ctgccagaat 480[0632] accacgtggt gggtccagtc cgagtagatg ccagtgggca ttttttgtca tatggcttgc 540[0633] actatcccat cacgagcagc aggaggaaga gagatttgga tggctcagag gactgggtgt 600[0634] actacagaat ttctcacgag gagaaggacc tgttttttaa cttgacggtc aatcaaggat 660[0635] ttctttccaa tagctacatc atggagaaga gatatgggaa cctctcccat gttaagatga 720[0636] tggcttcctc tgcccccctc tgccatctca gtggcacggt tctacagcag ggcaccagag 780[0637] ttgggacggc agccctcagt gcctgccatg gactgactgg atttttccaa ctaccacatg 840[0638] gagacttttt cattgaaccc gtgaagaagc atccactggt tgagggaggg taccacccgc 900[0639] acatcgttta caggaggcag aaagttccag aaaccaagga gccaacctgt ggattaaagg 960[0640] acagtgttaa catctcccag aagcaagagc tatggcggga gaagtgggag aggcacaact 1020[0641] tgccaagcag aagcctctct cggcgttcca tcagcaagga gagatgggtg gagacactgg 1080[0642] tggtggccga cacaaagatg attgaatacc atgggagtga gaatgtggag tcctacatcc 1140[0643] tcaccatcat gaacatggtc actgggttgt tccataaccc aagcattggc aatgcaattc 1200[0644] acattgttgt ggttcggctc attctactcg aagaagaaga gcaaggactg aaaatagttc 1260[0645] accatgcaga aaagacactg tctagcttct gcaagtggca gaagagtatc aatcccaaga 1320[0646] gtgacctcaa tcctgttcat cacgacgtgg ctgtccttct caccagaaag gacatctgtg 1380[0647] ctggtttcaa tcgcccctgc gagaccctgg gcctgtctca cctttcagga atgtgtcagc 1440[0648] ctcaccgcag ttgtaacatc aatgaagatt cgggactccc tctggctttc acaattgccc 1500[0649] atgagctagg acacagcttc ggcatccagc atgatgggaa agaaaatgac tgtgagcctg 1560[0650] tgggcagaca tccgtacatc atgtcccgcc agctccagta cgatcccact ccgctgacat 1620[0651] ggtccaagtg cagcgaggag tacatcaccc gcttcttgga ccgaggctgg gggttctgtc 1680[0652] ttgatgacat acctaaaaag aaaggcttga agtccaaggt cattgccccc ggagtgatct 1740[0653] atgatgttca ccaccagtgc cagctacaat atggacccaa tgctaccttc tgccaggaag 1800[0654] tagaaaacgt ctgccagaca ctgtggtgct ccgtgaaggg cttttgtcgc tctaagctgg 1860[0655] acgctgctgc agatggaact caatgtggtg agaagaagtg gtgtatggca ggcaagtgca 1920[0656] tcacagtggg gaagaaacca gagagcattc ctggaggctg gggccgctgg tcaccctggt 1980[0657] cccactgttc caggacctgt ggggctggag tccagagcgc agagaggctc tgcaacaacc 2040[0658] ccgagccaaa gtttggaggg aaatattgca ctggagaaag aaaacgctat cgcttgtgca 2100[0659] acgtccaccc ctgtcgctca gaggcaccaa catttcggca gatgcagtgc agtgaatttg 2160[0660] acactgttcc ctacaagaat gaactctacc actggtttcc catttttaac ccagcacatc 2220[0661] cttgtgagct ctactgccga cccatagatg gccagttttc tgagaaaatg ctggatgctg 2280[0662] tcattgatgg taccccttgc tttgaaggcg gcaacagcag aaatgtctgt attaatggca 2340[0663] tatgtaagat ggttggctgt gactatgaga tcgattccaa tgccaccgag gatcgctgcg 2400[0664] gtgtgtgcct gggagatggc tcttcctgcc agactgtgag aaagatgttt aagcagaagg 2460[0665] aaggatctgg ttatgttgac attgggctca ttccaaaagg agcaagggac ataagagtga 2520[0666] tggaaattga gggagctgga aacttcctgg ccatcaggag tgaagatcct gaaaaatatt 2580[0667] acctgaatgg agggtttatt atccagtgga acgggaacta taagctggca gggactgtct 2640[0668] ttcagtatga caggaaagga gacctggaaa agctgatggc cacaggtccc accaatgagt 2700[0669] ctgtgtggat ccagcttcta ttccaggtga ctaaccctgg catcaagtat gagtacacaa 2760[0670] tccagaaaga tggccttgac aatgatgttg agcagatgta cttctggcag tacggccact 2820[0671] ggacagagtg cagtgtgacc tgcgggacag gtatccgccg ccaaactgcc cattgcataa 2880[0672] agaagggccg cgggatggtg aaagctacat tctgtgaccc agaaacacag cccaatggga 2940[0673] gacagaagaa gtgccatgaa aaggcttgtc cacccaggtg gtgggcaggg gagtgggaag 3000[0674] catgctcggc gacatgcggg ccccacgggg agaagaagcg aaccgtgctg tgcatccaga 3060[0675] ccatggtctc tgacgagcag gctctcccgc ccacagactg ccagcacctg ctgaagccca 3120[0676] agaccctcct ttcctgcaac agagacatcc tgtgcccctc ggactggaca gtgggcaact 3180[0677] ggagtgagtg ttctgtttcc tgtggtggtg gagtgcggat tcgcagtgtc acatgtgcca 3240[0678] agaaccatga tgaaccttgc gatgtgacaa ggaaacccaa cagccgagct ctgtgtggcc 3300[0679] tccagcaatg cccttctagc cggagagttc tgaaaccaaa caaaggcact atttccaatg 3360[0680] gaaaaaaccc accaacacta aagcccgtcc ctccacctac atccaggccc agaatgctga 3420[0681] ccacacccac agggcctgag tctatgagca caagcactcc agcaatcagc agccctagtc 3480[0682] ctaccacagc ctccaaagaa ggagacctgg gtgggaaaca gtggcaagat agctcaaccc 3540[0683] aacctgagct gagctctcgc tatctcattt ccactggaag cacttcccag cccatcctca 3600[0684] cttcccaatc cttgagcatt cagccaagtg aggaaaatgt ttccagttca gatactggtc 3660[0685] ctacctcgga gggaggcctt gtagctacaa caacaagtgg ttctggcttg tcatcttccc 3720[0686] gcaaccctat cacttggcct gtgactccat tttacaatac cttgaccaaa ggtccagaaa 3780[0687] tggagattca cagtggctca ggggaagaaa gagaacagcc tgaggacaaa gatgaaagca 3840[0688] atcctgtaat atggaccaag atcagagtac ctggaaatga cgctccagtg gaaagtacag 3900[0689] aaatgccact tgcacctcca ctaacaccag atctcagcag ggagtcctgg tggccaccct 3960[0690] tcagcacagt aatggaagga ctgctcccca gccaaaggcc cactacttcc gaaactggga 4020[0691] cacccagagt tgaggggatg gttactgaaa agccagccaa cactctgctc cctctgggag 4080[0692] gagaccacca gccagaaccc tcaggaaaga cggcaaaccg taaccacctg aaacttccaa 4140[0693] acaacatgaa ccaaacaaaa agttctgaac cagtcctgac tgaggaggat gcaacaagtc 4200[0694] tgattactga gggctttttg ctaaatgcct ccaattacaa gcagctcaca aacggccacg 4260[0695] gctctgcaca ctggatcgtc ggaaactgga gcgagtgctc caccacatgt ggcctggggg 4320[0696] cctactggaa aagggtggag tgcaccaccc agatggattc tgactgtgcg gccatccaga 4380[0697] gacctgaccc tgcaaaaaga tgccacctcc gtccctgtgc tggctggaaa gtgggaaact 4440[0698] ggagcaagtg ctccagaaac tgcagtgggg gcttcaagat acgcgagatt cagtgcgtgg 4500[0699] acagccggga ccaccggaac ctgaggccat ttcactgcca gttcctggcc ggcattcctc 4560[0700] ccccattgag catgagctgt aacccggagc cctgtgaggc gtggcaggtg gagccttgga 4620[0701] gccagtgctc caggtcctgt ggaggtggag ttcaggagag aggagtgttc tgtccaggag 4680[0702] gcctctgtga ttggacaaaa agacccacat ccaccatgtc ttgcaatgag cacctgtgct 4740[0703] gtcactgggc cactgggaac tgggacctgt gttccacttc ctgtggaggt ggctttcaga 4800[0704] agaggattgt ccaatgtgtg ccctcagagg gcaataaaac tgaagaccaa gaccaatgtc 4860[0705] tatgtgatca caaacccaga cctccagaat tcaaaaaatg caaccagcag gcctgcaaga 4920[0706] aaagtgccga tttactttgc actaaggaca aactgtcagc cagtttctgc cagacactga 4980[0707] aagccatgaa gaaatgttct gtgcccaccg tgagggctga gtgctgcttc tcgtgtcccc 5040[0708] agacacacat cacacacacc caaaggcaaa gaaggcaacg gttgctccaa aagtcaaaag 5100[0709] aactctaagc ccaaa 5115[0710] <210>16

[0711] <211>528

[0712] <212>DNA

[0713] <213>人

[0714] <400>16

[0715] cgccagggag ctgtgaggca gtgctgtgtg gttcctgccg tccggactct ttttcctcta 60[0716] ctgagattca tctgtgtgaa atatgagttg gcgaggaaga tcgacctatt attggcctag 120[0717] accaaggcgc tatgtacagc ctcctgaaat gattgggcct atgcggcccg agcagttcag 180[0718] tgatgaagtg gaaccagcaa cacctgaaga aggggaacca gcaactcaac gtcaggatcc 240[0719] tgcagctgct caggagggag aggatgaggg agcatctgca ggtcaagggc cgaagcctga 300[0720] agctgatagc caggaacagg gtcacccaca gactgggtgt gagtgtgaag atggtcctga 360[0721] tgggcaggag atggacccgc caaatccaga ggaggtgaaa acgcctgaag aaggtgaaaa 420[0722] gcaatcacag tgttaaaaga aggcacgttg aaatgatgca ggctgctcct atgttggaaa 480[0723] tttgttcatt aaaattctcc caataaagct ttacagcctt ctgcaaaa 528[0724] <210>17

[0725] <211>2247

[0726] <212>DNA

[0727] <213>人

[0728] <400>17

[0729] tttcttgagc taggaaaggt ggttggctta cggcacagta gagagcttcc agggctggct 60[0730] ggcgtgggat acccgtacca cagaaatgca gggaccattg cttcttccag gcctctgctt 120[0731] tctgctgagc ctctttggag ctgtgactca gaaaaccaaa acttcctgtg ctaagtgccc 180[0732] cccaaatgct tcctgtgtca ataacactca ctgcacctgc aaccatggat atacttctgg 240[0733] atctgggcag aaactattca cattcccctt ggagacatgt aacgacatta atgaatgtac 300[0734] accaccctat agtgtatatt gtggatttaa cgctgtgtgt tacaatgtcg aaggaagttt 360[0735] ctactgtcaa tgtgtcccag gatatagact gcattctggg aatgaacaat tcagtaattc 420[0736] caatgagaac acctgtcagg acaccacctc ctcaaagaca accgagggca ggaaagagct 480[0737] gcaaaagatt gtggacaaat ttgagtcact tctcaccaat cagactttat ggagaacaga 540[0738] agggagacaa gaaatctcat ccacagctac cactattctc cgggatgtgg aatcgaaagt 600[0739] tctagaaact gccttgaaag atccagaaca aaaagtcctg aaaatccaaa acgatagtgt 660[0740] agctattgaa actcaagcga ttacagacaa ttgctctgaa gaaagaaaga cattcaactt 720[0741] gaacgtccaa atgaactcaa tggacatccg ttgcagtgac atcatccagg gagacacaca 780[0742] aggtcccagt gccattgcct ttatctcata ttcttctctt ggaaacatca taaatgcaac 840[0743] tttttttgaa gagatggata agaaagatca agtgtatctg aactctcagg ttgtgagtgc 900[0744] tgctattgga cccaaaagga acgtgtctct ctccaagtct gtgacgctga ctttccagca 960[0745] cgtgaagatg acccccagta ccaaaaaggt cttctgtgtc tactggaaga gcacagggca 1020[0746] gggcagccag tggtccaggg atggctgctt cctgatacac gtgaacaaga gtcacaccat 1080[0747] gtgtaattgc agtcacctgt ccagcttcgc tgtcctgatg gccctgacca gccaggagga 1140[0748] ggatcccgtg ctgactgtca tcacctacgt ggggctgagc gtctctctgc tgtgcctcct 1200[0749] cctggcggcc ctcacttttc tcctgtgtaa agccatccag aacaccagca cctcactgca 1260[0750] tctgcagctc tcgctctgcc tcttcctggc ccacctcctc ttcctcgtgg ggattgatcg 1320[0751] aactgaaccc aaggtgctgt gctccatcat cgccggtgct ttgcactatc tctacctggc 1380[0752] cgccttcacc tggatgctgc tggagggtgt gcacctcttc ctcactgcac ggaacctgac 1440[0753] agtggtcaac tactcaagca tcaatagact catgaagtgg atcatgttcc cagtcggcta 1500[0754] tggcgttccc gctgtgactg tggccatttc tgcagcctcc tggcctcacc tttatggaac 1560[0755] tgctgatcga tgctggctcc acctggacca gggattcatg tggagtttcc ttggcccagt 1620[0756] ctgtgccatt ttctctgcga atttagtatt gtttatcttg gtcttttgga ttttgaaag 1680[0757] aaaactttcc tccctcaata gtgaagtgtc aaccatccag aacacaagga tgctggcttt 1740[0758] caaagcaaca gctcagctct tcatcctggg ctgcacatgg tgtctgggct tgctacaggt 1800[0759] gggtccagct gcccaggtca tggcctacct cttcaccatc atcaacagcc tccaaggctt 1860[0760] cttcatcttc ttggtctact gcctcctcag ccagcaggtc cagaaacaat atcaaaagtg 1920[0761] gtttagagag atcgtaaaat caaaatctga gtctgagaca tacacacttt ccagcaagat 1980[0762] gggtcctgac tcaaaaccca gtgaggggga tgtttttcca ggacaagtga agagaaaata 2040[0763] ttaaaactag aatattcaac tccatatgga aaatcatatc catggatctc tttggcatta 2100[0764] tgaagaatga agctaaggaa aagggaattc attaaacata tcatccttgg agaggaagta 2160[0765] atcaaccttt acttcccaag ctgtttgttc tccacaatag gctctcaaca aatgtgtggt 2220[0766] aaattgcatt tctcttcaaa aaaaaa 2247[0767] <210>18

[0768] <211>1325

[0769] <212>DNA

[0770] <213>人

[0771] <400>18

[0772] accaatcctc acctctcacc tctgtgtccg ccctgctggg aaatattcca ggctttggcc 60[0773] aaggccagtg cagccccagg ttcccgagcg gcaggttggg tgcggaccat ggcctctcac 120[0774] aagctgctgg tgaccccccc caaggccctg ctcaagcccc tctccatccc caaccagctc 180[0775] ctgctggggc ctggtccttc caacctgcct cctcgcatca tggcagccgg ggggctgcag 240[0776] atgatcgggt ccatgagcaa ggatatgtac cagatcatgg acgagatcaa ggaaggcatc 300[0777] cagtacgtgt tccagaccag gaacccactc acactggtca tctctggctc gggacactgt 360[0778] gccctggagg ccgccctggt caatgtgctg gagcctgggg actccttcct ggttggggcc 420[0779] aatggcattt gggggcagcg agccgtggac atcggggagc gcataggagc ccgagtgcac 480[0780] ccgatgacca aggaccctgg aggccactac acactgcagg aggtggagga gggcctggcc 540[0781] cagcacaagc cagtgctgct gttcttaacc cacggggagt cgtccaccgg cgtgctgcag 600[0782] ccccttgatg gcttcgggga actctgccac aggtacaagt gcctgctcct ggtggattcg 660[0783] gtggcattcc tgggcgggac ccccctttac atggaccggc aaggcatcga catcctgtac 720[0784] tcgggctccc agaaggccct gaacgcccct ccagggacct cgctcatctc cttcagtgac 780[0785] aaggccaaaa agaagatgta ctcccgcaag acgaagccct tctccttcta cctggacatc 840[0786] aagtggctgg ccaacttctg gggctgtgac gaccagccca ggatgtacca tcacacaatc 900[0787] cccgtcatca gcctgtacag cctgagagag agcctggccc tcattgcgga acagggcctg 960[0788] gagaacagct ggcgccagca ccgcgaggcc gcggcgtatc tgcatgggcg cctgcaggca 1020[0789] ctggggctgc agctcttcgt gaaggacccg gcgctccggc ttcccacagt caccactgtg 1080[0790] gctgtacccg ctggctatga ctggagagac atcgtcagct acgtcataga ccacttcgac 1140[0791] attgagatca tgggtggcct tgggccctcc acggggaagg tgctgcggat cggcctgctg 1200[0792] ggctgcaatg ccacccgcga gaatgtggac cgcgtgacgg aggccctgag ggcggccctg 1260[0793] cagcactgcc ccaagaagaa gctgtgacct gcccactggc acacagctgg cactggcaca 1320[0794] cacct 1325[0795] <210>19

[0796] <211>2263

[0797] <212>DNA

[0798] <213>人

[0799] <400>19

[0800] agccagaggg acgagctagc ccgacgatgg cccaggggac attgatccgt gtgaccccag 60[0801] agcagcccac ccatgccgtg tgtgtgctgg gcaccttgac tcagcttgac atctgcagct 120[0802] ctgcccctga ggactgcacg tccttcagca tcaacgcctc cccaggggtg gtcgtggata 180[0803] ttgcccacag ccctccagcc aagaagaaat ccacaggttc ctccacatgg cccctggacc 240[0804] ctggggtaga ggtgaccctg acgatgaaag cggccagtgg tagcacaggc gaccagaagg 300[0805] ttcagatttc atactacgga cccaagactc caccagtcaa agctctactc tacctcaccg 360[0806] cggtggaaat ctccctgtgc gcagacatca cccgcaccgg caaagtgaag ccaaccagag 420[0807] ctgtgaaaga tcagaggacc tggacctggg gcccttgtgg acagggtgcc atcctgctgg 480[0808] tgaactgtga cagagacaat ctcgaatctt ctgccatgga ctgcgaggat gatgaagtgc 540[0809] ttgacagcga agacctgcag gacatgtcgc tgatgaccct gagcacgaag acccccaagg 600[0810] acttcttcac aaaccataca ctggtgctcc acgtggccag gtctgagatg gacaaagtga 660[0811] gggtgtttca ggccacacgg ggcaaactgt cctccaagtg cagcgtagtc ttgggtccca 720[0812] agtggccctc tcactacctg atggtccccg gtggaaagca caacatggac ttctacgtgg 780[0813] aggccctcgc tttcccggac accgacttcc cggggctcat taccctcacc atctccctgc 840[0814] tggacacgtc caacctggag ctccccgagg ctgtggtgtt ccaagacagc gtggtcttcc 900[0815] gcgtggcgcc ctggatcatg acccccaaca cccagccccc gcaggaggtg tacgcgtgca 960[0816] gtatttttga aaatgaggac ttcctgaagt cagtgactac tctggccatg aaagccaagt 1020[0817] gcaagctgac catctgccct gaggaggaga acatggatga ccagtggatg caggatgaaa 1080[0818] tggagatcgg ctacatccaa gccccacaca aaacgctgcc cgtggtcttc gactctccaa 1140[0819] ggaacagagg cctgaaggag tttcccatca aacgagtgat gggtccagat tttggctatg 1200[0820] taactcgagg gccccaaaca gggggtatca gtggactgga ctcctttggg aacctggaag 1260[0821] tgagcccccc agtcacagtc aggggcaagg aatacccgct gggcaggatt ctcttcgggg 1320[0822] acagctgtta tcccagcaat gacagccggc agatgcacca ggccctgcag gacttcctca 1380[0823] gtgcccagca ggtgcaggcc cctgtgaagc tctattctga ctggctgtcc gtgggccacg 1440[0824] tggacgagtt cctgagcttt gtgccagcac ccgacaggaa gggcttccgg ctgctcctgg 1500[0825] ccagccccag gtcctgctac aaactgttcc aggagcagca gaatgagggc cacggggagg 1560[0826] ccctgctgtt cgaagggatc aagaaaaaaa aacagcagaa aataaagaac attctgtcaa 1620[0827] acaagacatt gagagaacat aattcatttg tggagagatg catcgactgg aaccgcgagc 1680[0828] tgctgaagcg ggagctgggc ctggccgaga gtgacatcat tgacatcccg cagctcttca 1740[0829] agctcaaaga gttctctaag gcggaagctt ttttccccaa catggtgaac atgctggtgc 1800[0830] tagggaagca cctgggcatc cccaagccct tcgggcccgt catcaacggc cgctgctgcc 1860[0831] tggaggagaa ggtgtgttcc ctgctggagc cactgggcct ccagtgcacc ttcatcaacg 1920[0832] acttcttcac ctaccacatc aggcatgggg aggtgcactg cggcaccaac gtgcgcagaa 1980[0833] agcccttctc cttcaagtgg tggaacatgg tgccctgagc ccatcttccc tggcgtcctc 2040[0834] tccctcctgg ccagatgtcg ctgggtcctc tgcagtgtgg caagcaagag ctcttgtgaa 2100[0835] tattgtggct ccctgggggc ggccagccct cccagcagtg gcttgctttc ttctcctgtg 2160[0836] atgtcccagt ttcccactct gaagatccca acatggtcct agcactgcac actcagttct 2220[0837] gctctaagaa gctgcaataa agttttttta agtcactttg tac 2263[0838] <210>20

[0839] <211>2772

[0840] <212>DNA

[0841] <213>人

[0842] <400>20

[0843] cagtcggcac cggcgaggcc gtgctggaac ccgggcctca gccgcagccg cagcggggcc 60[0844] gacatgacga cagctcccca ggagcccccc gcccggcccc tccaggcggg cagtggagct 120[0845] ggcccggcgc ctgggcgcgc catgcgcagc accacgctcc tggccctgct ggcgctggtc 180[0846] ttgctttact tggtgtctgg tgccctggtg ttccgggccc tggagcagcc ccacgagcag 240[0847] caggcccaga gggagctggg ggaggtccga gagaagttcc tgagggccca tccgtgtgtg 300[0848] agcgaccagg agctgggcct cctcatcaag gaggtggctg atgccctggg agggggtgcg 360[0849] gacccagaaa ccaactcgac cagcaacagc agccactcag cctgggacct gggcagcgcc 420[0850] ttctttttct cagggaccat catcaccacc atcggctatg gcaatgtggc cctgcgcaca 480[0851] gatgccgggc gcctcttctg catcttttat gcgctggtgg ggattccgct gtttgggatc 540[0852] ctactggcag gggtcgggga ccggctgggc tcctccctgc gccatggcat cggtcacatt 600[0853] gaagccatct tcttgaagtg gcacgtgcca ccggagctag taagagtgct gtcggcgatg 660[0854] cttttcctgc tgatcggctg cctgctcttt gtcctcacgc ccacgttcgt gttctgctat 720[0855] atggaggact ggagcaagct ggaggccatc tactttgtca tagtgacgct taccaccgtg 780[0856] ggctttggcg actatgtggc cggcgcggac cccaggcagg actccccggc ctatcagccg 840[0857] ctggtgtggt tctggatcct gctcggcctg gcttacttcg cctcagtgct caccaccatc 900[0858] gggaactggc tgcgagtagt gtcccgccgc actcgggcag agatgggcgg cctcacggct 960[0859] caggctgcca gctggactgg cacagtgaca gcgcgcgtga cccagcgagc cgggcccgcc 1020[0860] gccccgccgc cggagaagga gcagccactg ctgcctccac cgccctgtcc agcgcagccg 1080[0861] ctgggcaggc cccgatcccc ttcgcccccc gagaaggctc agccgccttc cccgcccacg 1140[0862] gcctcggccc tggattatcc cagcgagaac ctggccttca tcgacgagtc ctcggatacg 1200[0863] cagagcgagc gcggctgccc gctgccccgc gcgccgagag gtcgccgccg cccaaatccc 1260[0864] cccaggaagc ccgtgcggcc ccgcggcccc gggcgtcccc gagacaaagg cgtgccggtg 1320[0865] taggggcagg atccctggcc gggcctctca agggcttcgt ttctgctctc cccggcatgc 1380[0866] ctggcttgtt tgaccaaaga gccctctttc cacgagactg aagtctgggg aggaggctac 1440[0867] agttgcctct ccgcctcctc cctggccccg gcccttccct cacttccatc catctctaga 1500[0868] cccccccaag gctttctgtg tcgctgcccc gggcgggtgt atccctcaca gcacctcacg 1560[0869] actgtgcctc aaagcctgca tcaataaatg aaaacggtct gcaccgctgc gggcgtgacg 1620[0870] ctcccggacg cgagtgggtg tggaattgct ttcctcgggc caccgtgggg gcacctctgg 1680[0871] cctcccgtga cccccaggcc gagggtcccc gggcacccag gtcggtcaag tctcggccct 1740[0872] ctcaggcccg cgtctctgcc tggaggagac tgtgtagggt ccggcgtggg gatcagccgg 1800[0873] gatgggctgc gcgtctccag cctctgcaca cacattggcg ggtggggtgc agggagggag 1860[0874] aggcagggga gagagaatgg catctcgcgt ggagggctgt cgtttgaact ctcccagcgc 1920[0875] gagagaccct gccccgcccc cttcctggag cgttgactcc cttctcgtct cgaggcctgt 1980[0876] ggcgtctggg tccgttgggg cagaaccatg gaggaaaagc cttcgaaagt gtcgctcaag 2040[0877] tcttccgacc gccaaggctc ggacgaggag agcgtgcata gcgacactcg ggacctgtgg 2100[0878] accacgacca cgctgtccca ggcacagctg aacatgccgc tgtccgaggt ctgcgagggc 2160[0879] ttcgacgagg agggccgcaa cattagcaag acccgcgggt ggcacagccc ggggcggggc 2220[0880] tcgttggacg aggggtacaa ggccagccac aagccggagg aactggacga gcacgcgctg 2280[0881] gtggagctgg agttgcaccg cggcagctcc atggaaatca atctggggga gaaggacact 2340[0882] gcatcccaga tcgaggccga aaagtcttcc tcaatgtcat cactcaatat tgcgaagcac 2400[0883] atgccccatc gagcctactg ggcagagcag cagagcaggc tgccactgcc cctgatggaa 2460[0884] ctcatggaga atgaagctct ggaaatcctc accaaagccc tccggagcta ccagttaggg 2520[0885] atcggcaggg accacttcct gactaaggag ctgcagcgat acatcgaagg gctcaagaag 2580[0886] cgccggagca agaggctgta cgtgaattaa aaacgccacc ttgggctcga gcagcgaccc 2640[0887] gaaccagccc cgtgccagcc cggtccccag acccaagcct gaccccatcc gagtggaatt 2700[0888] tgagtcctaa agaaataaaa gagtcgatgc atgaaaaaaa aaaaaaaaaa aaaaaaaaaa 2760[0889] aaaaaaaaaa aa 2772[0890] <210>21

[0891] <211>7909

[0892] <212>DNA

[0893] <213>人

[0894] <400>21

[0895] ttcaagtatg gcagacaaag gatgttctgc gtggggaaat gtggtgacac ccatttcaca 60[0896] aggacagctc acatagattg agtgctcagg aaggaccagc accataccca gtgcctgatg 120[0897] tgtatcatct caattagtcc ttgcctcaga tgcaaaagga aaccatcgcc atcatcatca 180[0898] ccaccatcat catcttcctc ctgtgcagat ggaaaggctg aggcatagag aggtgacgga 240[0899] gtctgcccag gactgcaagc ctgctggtgg cagagccagg ttccaatgga atgaaggctg 300[0900] tcatcctcag atggcagggt aggcaggtgg ctagagctca cttgggagaa ggggaaagga 360[0901] cactgacttt ggctagggat ggagcagagc ttgggctggc tttccatgca cgggcagggg 420[0902] gcgtggctca tggctacgct ccagccccgg gtgtggacat tgaatcttcc aggtctaccc 480[0903] taggctatgg gtctggacag cactgtgatg gaaagaagac actctatgtc ctgcattctg 540[0904] tgaccaatga tgtgactgtg ggaatggcgc tggcatctgg ctgccactct gggacgggtg 600[0905] gccagctgcc atcaggcccc acccaggatg ggaccaccat gcgacttctt ccctcgctcc 660[0906] tcctggtcat gtccagagcc ccaggaggac cagcaaagcc tctcgagccg atggcagctc 720[0907] acgttctgcc ttgtcagcta ctcctctcct gggcaatatt ggctgcttgc tgtggctctc 780[0908] cccggggtat gtgactgcct ctgtgctggg cacctggcct gggctttcct tctgggcctg 840[0909] ggcagctggg ctcagcttgg acccaggcag cagccacaga ggggcccatg gaggtgacag 900[0910] agttgcttct atgatggtga acgggcagct gtgacacgga ggaggcgacc actcctcagt 960[0911] ttccaagtgc tgcggtcagg gccggggcca gcaaagtccc tcccatattc aaagagcggg 1020[0912] tttgggtttg tcccaggagg acatagtcag gagcccatgc tgggacatgc ctcctccaaa 1080[0913] gttcagcctg gatccccagc ctctgccaac ggccccgctc cttagctaac ccagcttgct 1140[0914] cctgggttcc acggcggagt cagatgtttc tgggcagttt cacctttgtg ccttaaatgc 1200[0915] atgttgagga ctttaaggaa ttgtggagaa atagggctgt ggcaaaggca agtgacaact 1260[0916] gggaacaatg atcccgcaga ggctgctgag gcctgggccc caggggcgtg ggttcatcct 1320[0917] tctgcctggg ctttggtggg aggggcagac tctgtggtct gagacacaaa aaaacccaaa 1380[0918] acatatgtgt gtacagacac acagcagagc cacacacaca cttgtgccca tgcacacact 1440[0919] cacaggaggc ccgtggactc cgcacaggga agaaactcct ccggtcgaca gtggacggcg 1500[0920] ctgcagcagg gactcacccc caagccctgc ctgcctccca ttgcccacct ggccctggct 1560[0921] tgatgggctt atctcatgct gtggccgggg acctcttgct tcctgcaacc ccttgctgga 1620[0922] ctggggcctg ggcctctcct gggctgtgcc tagggtttgt aacccagggc ctgtgccggc 1680[0923] gtgcacagag catctctccc tgggaggctc agggctgcct cctcgagctc tgtgggcctg 1740[0924] cactggccgg tgagcttgtg gtgtgggttt tcaggctgta tccttctacc tcctgagccc 1800[0925] aggggtccca ggcgccctgc agctgtctcc tcggccatcc tgtggggccc cgaggccttg 1860[0926] ccctcacttc agtgcctggg tgctcaggct ttgcccaggt gccaggagaa ggtgtgagca 1920[0927] tgagcctatt ggacacacct ggcgacgtat accaggtgtc ccacccctgc caccatgggg 1980[0928] cctcccgata cggcaaccac cacggacctg tggggaccaa tgaggaaaga gagaggcagg 2040[0929] tctgggccag gctcacaggg actccggcat agcagaccct gccccagcag gcccccttgt 2100[0930] ccttcctggg tcctggtcct tcatgaggaa ctagcccatc cctggtgggg ctcccacccc 2160[0931] gcttctcagt gggctctatg cttgcctcgt cggagtcacc cctcaggcag tcctgggatc 2220[0932] ctctccttta gacccactgt gccttcccgg cctcccgggc ttctgctggg ggcagaagaa 2280[0933] atgcctcccc aggtctgtct ctggaggctc tgagggagat gggcttgggg gctgtaggag 2340[0934] gaggcaggga ttccagggtg tcaggaaggc aggggtgcca ggtcccacct agtgaagtaa 2400[0935] taaaccgtgg gtggtgatag tgacccagtg ccctcactgc ccagccccgc ctgtcctcag 2460[0936] ccagcactgc agggatccca ggcccagact ctggaggcct tcactgatcc cagccacccc 2520[0937] agaaaagctg cagcctgcag gcaccagccg ggccatatgc ccagtgccag ctagggccca 2580[0938] ccgcccatcc tgcacacggg gccgctgggc aggtgcccct cacaccccca ggatgtcagt 2640[0939] gctcacctcg agcaaagcgc cccagctcgg ccttgggagg tggtcatgtc cagggggatg 2700[0940] atggagagct gtccaaccaa gagagcggga gggagggaag gagggaggga gagagataga 2760[0941] gagagagaga gagagagagg aagtgtgggc cctaaggctg ccttagtgga ggtgcgcgtg 2820[0942] gcctgcacct caccaagcct agccactctc gcggctctga gtggctcaca ggcttgtgag 2880[0943] ggccccgtcg ctgcctgctg ggtccccacc agggctccct ctaggaatgc gccatggctg 2940[0944] ctatgacaat ttgcacagcc cagtggctta aacaccattt ataccacagg tccagatgaa 3000[0945] tcctgcaggg ccaaggtctg ggggtgctgg aggccatgct ccctccaggc ttgcggggag 3060[0946] aacttccctg cctcctccag tctctccatc cctgagctct cggctcctcc tccgtcttca 3120[0947] gggccagggc gtagcgtctg ctctctcggc ctctgcctcc gcttcccacc tcacctggct 3180[0948] tctgtctatg tcagtctccc tctgccaacc tcctagaagg acacttgtga ttacattagg 3240[0949] gctcacccct ttaatccagg ggagcctctc cacttcatga ttttcagcta acttgcttct 3300[0950] gcacagaccc cctttcccta taagggcaca cattcactgg tcccggggct aaggaccttg 3360[0951] ctccaagtcc ctccacccat gatgctgtgc cttccagaaa cctgtcctct gcagctcggt 3420[0952] cttgacccca agcctgctgg tgacctgaac ttcacagggt tatccccttg gactgtgtgc 3480[0953] agcacgatgc aatttctggg cctgaatgtc atgctccctg gggcaggacc ttgagcctgc 3540[0954] agcacacact aggccacctg cagtctcaca ggccatgccc tgggtagaca gggaggtgct 3600[0955] caaccccagc tcgggtcctc tagtctgcct ggctaccatg cttctcactc tcctgcatct 3660[0956] gcagaccctg cgttgccatg tgaggcaggg gtggggtggg gctgagggcg tggctttggt 3720[0957] ccctggctgt ccggatgaag taccagagtg acgccacagc ccatcccggt gacatgctca 3780[0958] cccccaaccc ccgtgtccgg gaccccggtc ttgtgtggtc cctgatgtgg agtcctcagt 3840[0959] ccttaagata catccagaaa gtcctggcca tgaattggag gtgcagagtc ctgcagagcc 3900[0960] tctgggctgg gctggtgccc ccaggagatg gagggcctgg tggatgccct cctccctcag 3960[0961] agctggggca gctgcctccc aggggtggga ctctgggctc agagagaggc ccttgagctg 4020[0962] cagctcaggg ggatgcgagg cttcgtggac tgtgtcctgg tccatgtggt gcacgtgtct 4080[0963] ccacctccaa ggagaggctc ctcagtgtgc acctccccca catccgtcct ctctgccggc 4140[0964] cccgggcgtc tgagcagtca ttccatgcca gcacctctgc agcctgctgg gcctcaggtt 4200[0965] ctctgtgagg gacctccccg gccttcggcg gaggtggagt aagctccgtc aaggcaggtg 4260[0966] gcttcgtccc ttcctgtgag tgacaccagt gatgaaatgg acccctccac acaggcatcc 4320[0967] tcagggcaca gggccctggg ggcaccttcc tcctttcgta tttgttgaga aaaaaagtgg 4380[0968] cattgcgctc acaccaggat gctggagcag agctgacatg ctcgggaaag ggcagaggtc 4440[0969] actgggggtg ggaaggtcat ccagtccaga ctcagcacct cgtgggctgg taaactgagg 4500[0970] ctcaaagtgc tggtgccagg cctgaggcct cgcggtgacc cctctctctg gttcccagca 4560[0971] cctgcctgag acctgcccca ggcacccata acctggaatt ccctgtttcc ttgtccaggg 4620[0972] cctgaggaaa tggctcccca ggtctgtctc tggatgctct gaggcagatg ggcttggggg 4680[0973] ctctaggagg aggcagggac tccagggtgt caggaaggca ggggtgccgg gtcccaccca 4740[0974] gtggagtaac aaactgtggg tggcgtttgg gcctccccgc cttccccact gggtgtgctg 4800[0975] gtgctggcgc tgctgggtca gggctgcccg tgaccccaga caccactgtc catcctgtga 4860[0976] ggctcccgtc tgggcatgtc ctgggtggat tcctcctttc tgttaagtag ctacatgagg 4920[0977] caggggctcc tggatccaaa gcaaatgaca ggaattccag agccaggtgc atccactcag 4980[0978] ggcagccagt gttggtggag ctgcctctag cacatggagg agagtgaaag tcagcctgcc 5040[0979] cctctcacga gaaaagaacc tggggatacc tctcagcctc cagcgttgca agtgcaaggc 5100[0980] cagtggagtt aatctgcaac gtgcacgagg gcgtgtgtca gtggctgtgt gcaggagtgt 5160[0981] gagtgagcaa gagcaagagc gcatggctcc tgctgtacct caaggtgtgg gctcctggtg 5220[0982] gctgctcagt gttcccaggg gtgagaggcc tcatgtatcc taggctgcct gagatttctg 5280[0983] tgtgctgatc gcatcctcag tttcttgtcc accgcttcac tggcaagagt cccaggctcc 5340[0984] aaggacaccc tccctgcaca tgattgggtg ttaatggtgg cctgggttgt gtcttcccct 5400[0985] ggggatgagg gttgggtgtc catggtgccc tgggctgtgt cctcccctag ggatgagggt 5460[0986] cgggcctcca cgatgccctg ggctgtgtgc tcttatggga atgagggttg ggtgtccaag 5520[0987] atgccctggg ctgtgtcctt ccctggggat gagggttgga tgtccaagat gccctgggct 5580[0988] gtgtactccc ctaggaatga gggctgggtg tccaagatac cctgggctgt gtcctcccct 5640[0989] ggggatgagg gttgggtgtc catggtgccc tgggctgtgt cctcccctgg ggatgacggt 5700[0990] tgggtgtcca tggtgccctg ggctgtgttt ccttggggat gagggttggg tgctatggca 5760[0991] tcctgggcag gtgcttcctt tctgcacaag ggttgggtga ccatgatgtc ctggcaatgg 5820[0992] cttccctggg ttgcctcttt tctgccatgt gggaagagca ggggaggttt agttggtctc 5880[0993] agcacatcat tctctcagga taagtagaag agtgtctgag ctgtgaggcc agtgctccag 5940[0994] ctttggaatt gtcttcccca ccctcacctc catcccatca aagcccgaca tgtcgtgtgg 6000[0995] cagcagcgag gtgggtgttg gctgttctct tgggctgggg gttagtcgtg gacggggaaa 6060[0996] ggagagatgc tggtcaaagg gcatgaagtt tctgctgatg ggaggagtca gttcttttga 6120[0997] tctgttgcac agcatggtga ctatagttaa caataatgac tatttcaaaa ttgctaaaag 6180[0998] atgagatttt aaatgttctc accacaaaat gataagtgtg tgaggtgatg gatatgccac 6240[0999] ttaccttgtt ttaatcatcc cacaatatag acaggcattg tcactttgca ttgtacccca 6300[1000] ggaatcttca catttgcttt tttgtcaatt aaaaatagag acacaaaagg agagagggga 6360[1001] gagcaataga ctcttcacgg aaccgtgggc ttctgcctcc gggtaaaata aactgcaaaa 6420[1002] aggattccca ggaaaccgtt ccctctttca gcccttggtt acaggaagcc ggatttggga 6480[1003] aatctgcctg gatgacattc acatgaacgg gcacatacag gaaaacacgg taatgtaatt 6540[1004] agaatagtca gagaaaagta gccagaaatg acattcacat gaacgggcac atacaggaga 6600[1005] aaacacggta acgtaattag aatagtcaga gaaaagtagc cagaaatgac attcacatga 6660[1006] acgggcacat ataggagaaa ccatggtaac gtaattagaa tagtcagaga aaagtagcca 6720[1007] gaaatgacat tcacatgaac gggcacatac aggaaaacac ggtaatgtaa ttagaatagt 6780[1008] cagagaaaag tagccagaaa tgacattcac atgaacgggc acatacagga gaaaacacgg 6840[1009] taacgtaatt agaatagtca gagaaaagta gccagaaatg acattcacat gaacgggcac 6900[1010] atacaggaga aaacacggta acgtaattag aatagtcaga gaaaagtagc cagaagaatt 6960[1011] tgcaacgtgc ccttgtaaca ccaaatttga tcagtttttt aaaaaatgat cgttatgtag 7020[1012] gtgattgaga agtaaatgta ttctttttta aggtaaaaat ttggaccctt atcatgcata 7080[1013] cccccctctg tgctcttcaa atcaacatca ttattaatat ctgtacattt ttgctcatct 7140[1014] gagccagcac aggctgaggc tgtcagaatg gacacctttt ggttgttggg tttctgtcag 7200[1015] tttctggggt gaagctgcgt gattgagaac gtagctcttg gctgccatct cggggattat 7260[1016] taaggactgt gaactctatc cacaagccat ggcaatatct gtcccaccga atgctccctc 7320[1017] taacacactc ttactcccgt gatgtgtgtt aagggctccg atgatgctga aaacagcaca 7380[1018] ggatgtgaaa aggcaggaac agttctgaag tcaaaggctg atgtcctgtt tctctttccc 7440[1019] tctgtgaccg actcccttcc cagtggtaac aagtacccac agcttggttt gaatttctgc 7500[1020] acgctgttgt ctgtgcactc gctcacactt acgcacacag caggcatgtg ggcgatgctg 7560[1021] ggtattttgt gtatgagtgg gatgcacata cacacatcta catccatatc atgcccatgc 7620[1022] atctgtaact tgcttttccc gtgtaagaac acttcttaga gtttgttcaa tgcatgtgtc 7680[1023] tgtgtgaatg attgaaggca tttctaaccc attttaaaga tggctactta ggaccatatg 7740[1024] gatgttgtac tgatgtcatt tgaccacgtc cattgtttcc atcttttggg ctgttcttgt 7800[1025] gtattttact ttccatgtaa cactgtgaca ttgagaattg gtacctacaa cagtctattt 7860[1026] gctttacatt aaatttgtag gctaatttgt gtaaaaaaaa aaaaaaaaa 7909[1027] <210>22

[1028] <211>1072

[1029] <212>DNA

[1030] <213>人

[1031] <400>22

[1032] agtcagtgaa acggcagaat cagaagaggt tccacaacca gaaaatcttg gctggaattt 60[1033] caccatcagg aataaaacag aaaaactaaa agagtgcccc agatagcctt tcttaggggc 120[1034] ctgtgacagg tcgcaggaat cttgttggtg atccatccag atgttgtgtg ttctggaagt 180[1035] ggacatcgcg gctctgtgtt tttgaagtca gatctcattg ctgtggtttc tatgcctgac 240[1036] cccccgaagt tcttgctcct gttgccacag ggagccggga gagcacagag cgctgctccc 300[1037] ggtgccctgc agccacacaa acatgctcct gctcctggcg gaggcagagc tgctgggaaa 360[1038] gacatttcgg aagtttcctg tggctgcaac aaattgttca aatctgcact ggagcaccgc 420[1039] tgtgacctgt ctttctccat cttagggcaa acagctcctg aaactggaaa ctccccagca 480[1040] cctactcacc ctacccctca ggctctcctt gtgggggtgg ggcaggggga gttgtctgga 540[1041] atgcctggcc tctctgtcca agcatggcag ccttgcccca tgggtggtgc agactcagtt 600[1042] tcccatgcac cttgccccag ggaggaggta ggggttcctt ccatagagat ggtgaagaat 660[1043] aagggaggta gtgatcgtct ctgggatcca gttagatctg cgtttgcagg cagaaagagg 720[1044] ctggggcaca tggagagagt gatcaactgg aagattctag ggtcctcaat tttgaaaggt 780[1045] gacatgatac cctggaaagg gcatgaactt agttgtcagt tcgtccttgc cttttccaat 840[1046] caatgctgtg tggccacggc aaattaatga acatctctga gtttcggtct cctgtctaaa 900[1047] atgaggtgat aatagcttct tgaaggttgt aaggccccaa acatgctgcc tggcacatag 960[1048] atggctaatc aatattttcc tacccttccc ttccttccct tctctggagt tgctacctgt 1020[1049] cttctcctgg ggccttgcaa ataaacttct gaattaaaaa aaaaaaaaaa aa 1072[1050] <210>23

[1051] <211>417

[1052] <212>DNA

[1053] <213>人

[1054] <400>23

[1055] acctcccaac caagccctcc agcaaggatt caggagtgcc cctcgggcct cgccatgagg 60[1056] ctcttcctgt cgctcccggt cctggtggtg gttctgtcga tcgtcttgga aggcccagcc 120[1057] ccagcccagg ggaccccaga cgtctccagt gccttggata agctgaagga gtttggaaac 180[1058] acactggagg acaaggctcg ggaactcatc agccgcatca aacagagtga actttctgcc 240[1059] aagatgcggg agtggttttc agagacattt cagaaagtga aggagaaact caagattgac 300[1060] tcatgaggac ctgaagggtg acatccagga ggggcctctg aaatttccca caccccagcg 360[1061] cctgtgctga ggactcccgc catgtggccc caggtgccac caataaaaat cctaccg 417[1062] <210>24

[1063] <211>1011

[1064] <212>DNA

[1065] <213>人

[1066] <400>24

[1067] ttcctcatta aagtttcaca aataaagcac agcaagactt gtctgcagac acacaggagg 60[1068] cacacggaca gcccgtcaac cagagatgga gacgaaggcc agcatggctc tcacagggca 120[1069] gcgcttctca gaacccctgg cccccctcgt gccaaggctg gcctgtgtca ggcctcgccc 180[1070] acgccgcctt atgacaaata gargccggtg ccaaggaggt ggctacagag caggggcaag 240[1071] gaagttatcc tcatgttctg ataatgaccc tgcaaatccc accccaccct caggcacctc 300[1072] cgtctaaggt gtccggttac tccaggtaag gaggttccca ggagggccgt gttttcccta 360[1073] gggctgatga aacttgctcc gacaagccag gccactggga ggcacctcag gatggaaaag 420[1074] atgctgagag gctttgctgg ctttcaggat gccgggwgcc ccacgggggc aaaaggggag 480[1075] gaaggaaaga rattctaaag acagattgct gctggtctgt cccgacccag ggtcacagtg 540[1076] tcagcaaaga gaacagcatg attctgacag ggttggattt tgtttcaccc tcggaatgag 600[1077] cagacattca aacacttgca ttttcacgga aatcaacaag agagacagct agcaggacac 660[1078] gaggctcctg ccagttctgt gtggaaaggc accagatggt ttgttatgaa acacattttg 720[1079] gtcagaaaat agctggggtt ttttggttcc tgggaggaca acaaagctag aagaaaarga 780[1080] ggtgtgagtt gcgtgaggag gaggcagaga agaaagcagc tttggcatca gacctgggtt 840[1081] ctactcttca ctctacccct cmacgcttga ggcctcagtt tcctcatctg taaagtggtc 900[1082] atagaatatt tccaaataaa tctaggtgtc aggtttcaca catymtccca ggaagtatgg 960[1083] ggaggcgggg cgcagacact caaacggaca cacagaaacc agaggaagag c 1011[1084] <210>25

[1085] <211>2123

[1086] <212>DNA

[1087] <213>人

[1088] <400>25

[1089] tagctgatca tgtgacaatc caagatggcg gtgcccggcg aggcggagga ggaggcgaca 60[1090] gtttacctgg tagtgagcgg tatcccctcc gtgttgcgct cggcccattt acggagctat 120[1091] tttagccagt tccgagaaga gcgcggcggt ggcttcctct gtttccacta ccggcatcgg 180[1092] cctgagcggg cccctccgca ggccgctcct aactctgccc taattcctac cgacccagcc 240[1093] gctgagggcc agcttctctc tcagacttcg gccaccgatg tccggcctct ctccactcga 300[1094] gactctactc caatccagac ccgcacctgc tgctgcgtca tctcggtaag ggggttggct 360[1095] caagctcaga ggcttattcg catgtactcg ggccgccggt ggctggattc tcacgggact 420[1096] tggctaccgg gtcgctgtct catccgcaga cttcggctac ctacggaggc atcaggtctg 480[1097] ggcccctttc ccttcaagac ccggaaggaa ctgcagagtt ggaaggcaga gaatgaagcc 540[1098] ttcaccctgg ctgacctgaa gcaactgccg gagctgaacc caccagtgct gatgcccaga 600[1099] gggaatgtgg ggactcccct gcgggtcttt ttggagttga tccgggcctg ccgcctaccc 660[1100] cctcggatca tcacccagct gcagctccag ttccccaaga caggttcctc ccggcgctac 720[1101] ggcaatgtgc cttttgagta tgaggactca gagactgtgg agcaggaaga gcttgtgtgt 780[1102] acagcagagg gtgaagaaat accccaagga acctacctgg cagatatacc agccagcccc 840[1103] tgtggagagc ctgaggaaga agtggggaag gaagaggaag aagagtctca ctcagatgag 900[1104] gacgatgacc ggggtgagga atgggaacgg catgaagcgc tgcatgagga cgtgaccggg 960[1105] caggagcgga ccactgagca gctctttgag gaggagattg agctcaagtg ggagaagggt 1020[1106] ggctctggcc tggtgtttta tactgatgcc cagttctggc aggaggaaga aggagatttt 1080[1107] gatgaacaga cagccgatga ctgggatgtg gacatgagtg tgtactatga cagagatggt 1140[1108] ggagacaagg atgcccgaga ctctgtccaa atgcgtctag aacagagact ccgagatgga 1200[1109] caggaagatg gctctgtgat cgaacgccag gtgggcacct ttgagcgcca caccaagggc 1260[1110] attgggcgga aggtgatgga gcggcagggc tgggctgagg gccagggcct gggctgcagg 1320[1111] tgctcagggg tgcctgaggc cctggatagt gatggccaac accccagatg caagcgtgga 1380[1112] ttggggtacc atggagagaa gctacagcca tttgggcaac tgaagaggcc ccgtagaaat 1440[1113] ggcttggggc tcatctccac catctatgat gagcctctac cccaagacca gacggagtca 1500[1114] ctgctccgcc gccagccacc caccagcatg aagtttcgga cagacatggc ctttgtgagg 1560[1115] ggttccagtt gtgcttcaga cagcccctca ttgcctgact gaccgggttg ggggcttcct 1620[1116] ttcatagcta catgatgaaa accctctgcc ctggcctcat ctaccactga agcagaaagg 1680[1117] agtctgggag cagcagtctt cgtggctggt tcagggtgtt ttgttccgag cctgcctgcc 1740[1118] tgccggttct atacctcagg ggcattttta caaaaagccc cctcccgtcc cctccccttg 1800[1119] gatattaggg gtaacgaccg cttgtctttg gtctctaacc ctaatctctg ggcttgccct 1860[1120] ttgcctcctg cagaactttg aaaagctggg ttgagtgagg ctatcagcac agccttcctt 1920[1121] ggggactctg aaggtgtccc cacgaaggcc agaaaggggg aaagggacct gggcgaggag 1980[1122] aggatttgtg gtgcttggaa gagccggcct tgggtgggcc ctccaccgcc tctaccctca 2040[1123] ctgggtggga ctgccagcgg agagtccgcg ggaggtggct tgggtgtgcg acgtcacgga 2100[1124] agaataaaga cgtttactac tgg 2123[1125] <210>26

[1126] <211>1276

[1127] <212>DNA

[1128] <213>人

[1129] <400>26

[1130] ggaatccacc cggggtgtgt ggattcctgc cctgttccca caggacagcc ctcaaccaat 60[1131] ggagacagga acctggagtt aaatgcttct ccctttttca ctgagagaga gacatgcaca 120[1132] gtctgatgca ctttctttcc ttctttcttt ttctttcttt ttttttctta agacagagtc 180[1133] tctctctgtc accaaggctg gagtgcaggg gcacgatctg ggctcactgc cacctccacc 240[1134] tcccgggttc aagcaattct cccacctcag cctcccgagt agctgggatt acaggcacta 300[1135] gttaccacgc ccagctaatt tttgtatttt tagtagagat gcggtttcac catattggtc 360[1136] aggctggtct cagactcctg atctcaggta atctgtctgc ctcagcctcc caaggtgctg 420[1137] gaattacagg catgagccac cacacctggc cgtgatgcac tttctagatg ctgtcctaga 480[1138] gatcacactg tgttaagcct cagttgcctt caatgtggtc atctctacag tataccctta 540[1139] gcttttttct cctccgttac tttcccagac cctcactctg ctccctggat tcacttttcg 600[1140] aaatagtcct cctgctgcaa agtcctgggc acctgcccta ctttcagcat tggaaggggg 660[1141] gcccaggcta agaccatgag gccccactgt gggcgcccac agccccgttc ctccctctat 720[1142] tcccaccaca gtcacatcct cctgtccctc agtgcttcct cgcctttccc tccagcccac 780[1143] cgtgagatcc caggggacgg agcagcccct tctctgcccc agtgcagggc ttggccttag 840[1144] cacacggtca gtctgtgctg gggtgaagtg atgaatgagt gagtggttga gtgataatgc 900[1145] atcatcagat ctgtcttttc cacatgtctc tatctccacc cagaaccagt tttctcatcc 960[1146] acaaatgggc atttgaggct gggtgctcct aaaccctaca aaattcagag ctggcacagt 1020[1147] tggggactga ccttccttga tctcacctca ctttctgtat ctataaaatg gggtaccttt 1080[1148] ctctaagagt aaaaaggagg cctggcatag ggaaagaaac tcagctcgag catccagaac 1140[1149] atccatcttg ctctcaaata cctaatacag gggaccatgt tttctgctat aattggtatt 1200[1150] ggagctggta ccatttatta aaggtaattc agttacaaag cttcaaaaaa aaaaaaaaaa 1260[1151] aaaaaaaaaa aaaaa 1276[1152] <210>27

[1153] <211>7764

[1154] <212>DNA

[1155] <213>人

[1156] <400>27

[1157] ccctgggatg gaggatctgt ctctctctct ctctctcctt tttttttttt tggtggagat 60[1158] gaaggggtgg gtctatggta catcacctga gttgtggggt aaatgtagag agtgtcaatc 120[1159] aaaggcagag ctctcagagc tgggaaggag gctctagatg gcggctgtgc cttagagaga 180[1160] gcgcgctctg ctccctgcct ttgcctcact ttacgcaact ttccctaact ttcgggcagc 240[1161] ctcagggggc ccccgtagcc ccctgccttt cctagggact tactggggtc gattcgaacc 300[1162] tttttttggg agaaaagcag cttttaggag ctttcttttc gtgccttgtt ggaaagaagc 360[1163] agccgtactg agagcccagg tcgttgtttt ttccagctta gaagccatgg cgcacctcca 420[1164] tttttgtgcg ctctcctaat gaggtttttt ttctttcgga cctgttttag tattaattat 480[1165] tgctttattt ttttgaccag ttaacatatt tgagggttat tttatttatt tttcgttttt 540[1166] taacggagga ttttgccttt atttttaatt atttgggatc tgatattttt ctactagtag 600[1167] ataggactct tggtttggac atactacatg gatcagtaaa tacctgggca caggacttca 660[1168] aagcaaacac agattccccc tcccccttaa tatttaagaa ttaaaagatg atgagaaata 720[1169] aggacaaaag ccaagaggag gacagttcgc tacacagcaa tgcatcgagt cactcagcct 780[1170] ctgaagaagc ttcgggttca gactcaggca gtcagtcgga aagtgagcag ggaagtgatc 840[1171] caggaagtgg acatggcagc gagtcgaaca gcagctctga atcttctgag agtcagtcgg 900[1172] aatctgagag cgaatcagca ggttccaaat cccagccagt cctcccagaa gccaaagaga 960[1173] agccagcctc taagaaggaa cggatagctg atgtgaagaa gatgtgggaa gaatatcctg 1020[1174] atgtttatgg ggtcaggcgg tcaaaccgaa gcagacaaga accatcgcga tttaatatta 1080[1175] aggaagaggc aagtagcggg tctgagagtg ggagcccaaa aagaagaggc cagaggcagc 1140[1176] tgaaaaaaca agaaaaatgg aaacaggaac cctcagaaga tgaacaggaa caaggcacca 1200[1177] gtgcagagag tgagccagaa caaaaaaaag taaaagccag aagacctgtc cccagaagaa 1260[1178] cagtgcccaa acctcgtgtt aaaaagcagc cgaagactca gcgtggaaag agaaaaaagc 1320[1179] aagattcttc tgatgaggat gatgatgatg acgaagctcc caaaaggcag actcgtcgaa 1380[1180] gagcggctaa aaacgttagt tacaaagaag atgatgactt tgagactgac tcagatgatc 1440[1181] tcattgaaat gactggagaa ggagttgatg aacagcaaga taatagtgaa actattgaaa 1500[1182] aggtcttaga ttcaagactg ggaaagaaag gagccactgg agcatctact actgtatatg 1560[1183] cgattgaagc taatggcgac cctagtggtg actttgacac tgaaaaggat gaaggtgaaa 1620[1184] tccagtacct catcaagtgg aagggttggt cttacatcca cagcacatgg gagagtgaag 1680[1185] aatccttaca gcaacagaaa gtgaagggcc taaaaaaact agagaacttc aagaaaaaag 1740[1186] aggacgaaat caaacaatgg ttagggaaag tttctcctga agatgtagaa tatttcaatt 1800[1187] gccaacagga gctggcttca gagttgaata aacagtatca gatagtagaa agagtaatag 1860[1188] ctgtgaagac aagtaaatct acattgggtc aaacagattt tccagctcat agtcggaagc 1920[1189] cggcaccctc aaatgagccc gaatatctat gtaaatggat gggactcccc tattcagagt 1980[1190] gtagctggga agatgaagcc ctcattggaa agaaattcca gaattgcatt gacagcttcc 2040[1191] acagtaggaa caactcaaaa accatcccaa caagagaatg caaggccctg aagcagagac 2100[1192] cacgatttgt agctttaaag aaacaacctg catatttagg aggggagaat ctggaacttc 2160[1193] gagattatca gctagaaggt ctaaactggc tagctcattc ctggtgcaaa aataatagtg 2220[1194] taatccttgc tgatgaaatg ggcctaggaa agaccatcca gaccatatca ttcctctcct 2280[1195] acctgttcca ccaacaccag ctgtatggcc cctttcttat agtcgtccct ttatccaccc 2340[1196] tcacctcatg gcagagagag tttgaaatct gggcaccaga gattaacgta gtggtttaca 2400[1197] taggtgacct gatgagcaga aatacgatac gggaatatga atggattcat tcccaaacca 2460[1198] aaagattgaa gttcaacgca cttataacaa catatgagat cctcttgaaa gataagactg 2520[1199] tgctgggcag tattaactgg gcctttctgg gagtggatga agcccatcgg ttgaagaatg 2580[1200] atgactcttt attgtataaa actctgattg atttcaagtc caaccatagg ctcctgatta 2640[1201] cggggacccc tcttcagaat tccctcaaag agctctggtc cttgctgcac tttattatgc 2700[1202] cggagaagtt tgaattttgg gaagattttg aagaagacca tgggaagggg agagagaatg 2760[1203] gctaccagag tcttcataag gtgctagagc ctttccttct ccggagagtc aaaaaagatg 2820[1204] tggagaaatc ccttcctgct aaagtggaac agattctcag ggtggagatg tcagcccttc 2880[1205] agaaacagta ttacaagtgg attctgacca ggaattacaa ggctcttgcc aaaggaacaa 2940[1206] gaggcagcac atctggtttt cttaatattg tgatggaact gaaaaaatgt tgcaaccact 3000[1207] gctatctgat taaaccccct gaagaaaatg aaagggaaaa tggacaggag attcttctgt 3060[1208] ccctcataag gagcagtggg aagttgattt tattagacaa actgttgaca agacttcgag 3120[1209] aaagggggaa tcgagtgctt atcttctctc agatggtgag aatgttggat atcctggctg 3180[1210] aatacctaac tattaaacac tatcctttcc agcgtctgga tggttccatc aagggagaaa 3240[1211] tccgaaaaca ggcactggac cacttcaatg cagatgggtc tgaggacttc tgtttcctgc 3300[1212] tctcgacaag ggctggtggc ctgggaatca atttggcttc agcggacaca gtcgtcatct 3360[1213] ttgactctga ctggaacccc cagaatgact tgcaggcaca agcccgagcg catagaattg 3420[1214] gtcagaagaa gcaggtaaat atttaccgct tagttacaaa ggggactgtg gaggaggaga 3480[1215] tcatagaacg ggccaaaaag aagatggtat tagatcatct ggtgattcag cgcatggaca 3540[1216] ccactggccg gacgatcctg gaaaacaact caggaaggtc caactcaaat ccttttaata 3600[1217] aagaagagct gacagctatt ttgaaatttg gagcagagga tctcttcaaa gaactggaag 3660[1218] gggaggaatc agaacctcag gaaatggata tagatgaaat tttgcggttg gctgaaacga 3720[1219] gagagaatga agtgtcaaca agtgcaacag atgaacttct atcacagttt aaggttgcca 3780[1220] actttgcaac aatggaagat gaagaagagc tagaagagcg tcctcacaag gactgggatg 3840[1221] agatcattcc agaggaacaa aggaaaaaag tagaggagga agagcggcag aaggagctag 3900[1222] aagaaattta tatgctgcct cgaattcgga gttccactaa aaaggctcag acaaatgaca 3960[1223] gtgactctga cactgagtct aagaggcagg cccagagatc ctctgcttct gagagtgaaa 4020[1224] cggaagactc tgatgatgac aagaagccaa agcgcagagg gcgtccgagg agtgtgcgga 4080[1225] aggacctcgt ggagggattt actgatgcag agatccgaag gttcatcaag gcttataaga 4140[1226] agtttggtct ccctcttgaa cggctggagt gcttagcacg tgatgctgag ctggtagata 4200[1227] agtcggtggc agatctgaag cgcctgggtg aactgatcca caacagctgt gtgtcagcaa 4260[1228] tgcaggaata tgaagagcag ctgaaagaaa atgccagcga gggaaaagga ccagggaaaa 4320[1229] ggagaggtcc aacaatcaag atatccggag ttcaggttaa tgtgaaatcc attatccaac 4380[1230] atgaagagga gtttgagatg ctgcataaat ctatccctgt ggaccctgaa gaaaaaaaaa 4440[1231] aatactgctt aacctgtcgt gtcaaagctg cacattttga tgtagagtgg ggggtggaag 4500[1232] atgattctcg cctgttgctg gggatttatg aacatggcta tggaaactgg gagttaatta 4560[1233] aaacagaccc agagcttaaa ttaactgaca aaattctgcc ggtggagaca gataaaaagc 4620[1234] ctcaggggaa gcagctacag acccgagcgg attacttgtt gaagctgctc agaaagggtc 4680[1235] tggagaagaa gggggctgtg acaggtgggg aggaggccaa attaaagaag cggaagcctc 4740[1236] gggtaaagaa ggaaaacaaa gtgcccaggc tgaaagagga gcatggaatt gagctttcat 4800[1237] ctcctaggca ttcagataat ccatcagaag agggagaagt gaaagatgat ggcttggaaa 4860[1238] aaagtccaat gaaaaaaaaa cagaagaaga aagagaacaa ggagaacaag gagaaacaaa 4920[1239] tgagttctag gaaagacaaa gaaggggaca aggaaagaaa gaagtcaaaa gataagaaag 4980[1240] agaagcctaa aagtggtgat gccaaatctt cgagtaaatc aaagcgatct cagggtcctg 5040[1241] tccatattac agcaggaagt gaacctgtcc ccattggaga ggatgaggat gatgatctgg 5100[1242] accaggagac attcagcata tgtaaggaga ggatgaggcc cgtgaaaaag gcactgaaac 5160[1243] agctcgacaa acctgacaag gggctcaacg tgcaagaaca gctggaacac acccggaact 5220[1244] gcctgctgaa aatcggagac cggatagccg agtgccttaa agcctactca gatcaggagc 5280[1245] acatcaaact ctggaggagg aacctatgga tttttgtttc caagtttaca gaatttgatg 5340[1246] ctcgaaaact gcataagtta tacaagatgg ctcataagaa aaggtctcaa gaagaagagg 5400[1247] agcaaaagaa gaaagacgac gtgactgggg gtaagaaacc atttcgtcca gaggcctcag 5460[1248] gctccagccg ggactctctg atatctcagt cccatacctc acacaacctt caccctcaga 5520[1249] agcctcattt gcctgcctcc catggcccac agatgcatgg acacccaaga gataactaca 5580[1250] atcaccccaa caagagacac ttcagtaatg cagatcgagg agactggcag agggaaagaa 5640[1251] agttcaacta tggtggtggc aacaacaatc caccatgggg aagcgacagg caccatcagt 5700[1252] atgagcagca ctggtacaag gaccaccatt atggggaccg gcgacatatg gatgcccacc 5760[1253] gttccggaag ctatcgaccc aacaacatgt ccagaaagag gccttatgac cagtacagca 5820[1254] gtgaccgaga ccaccgggga cacagagatt attatgacag gtatgcaaaa ggctgtgaga 5880[1255] caccaggtgc caacctttgc caggagctgt ttctagggag aaagtgacgt atacatgaat 5940[1256] gtatttatct atcaaattac tgaagatctc atcatgcatg tgtcagccac agcgaatccc 6000[1257] atgtcttggt tataggtttt atgttttgtt ttctgggtca tagggagcac atttcacctg 6060[1258] tgcaggaaaa gagttttctg ccgtcttttg aggaaatcta gtgaagaggt cgccataaaa 6120[1259] tattagagtc aacaaccaaa attattaagc tctgtgcgag gctgtcagcc acactaggta 6180[1260] tcagggatcc cgagatgggt accagcccac agtccttacc tgccacgagc ccataattga 6240[1261] agagtcaaag tcttctgaag ctgcaccctc tttacttcag tacaatgcca ccagtagtac 6300[1262] gatgagccaa agctttacat tgtgagagta gcaagtccag ggagagctaa agaggtttta 6360[1263] tctgtatttc ctaatttcaa atcttggata atttaacctc atagcagctt tggttttccc 6420[1264] tgggctgatg atgtgcgtca tttgcactgt accttgaatt tacagtggga aaatttcata 6480[1265] taaacgtgtc aaagtcgtgc tttgtttttg gaagatctgg taacagcagc ccgcattagc 6540[1266] agagagctgt agctgagtag ctgccacctc gttgggagac tgcccctcgc tcccaccctt 6600[1267] ctctattgtc tggacccagt gggcatcttg ccctgcgttc ttctagtagg tctgtatttc 6660[1268] tatttgatgt cactttcctt ttgcctgaag gactttttct gctggtgata aactctttca 6720[1269] gtgtttgtat atatgcctga aaaagtattt tgccttcatt tttgaaagta gtttttgctg 6780[1270] agtgtataca tttttggctt tacagtttct ttcagtgctt taaagatgta cctctgctat 6840[1271] ttacttgcat tgttttgtga tgaaaaatct gtcatcctta tctttgttcc tctttacata 6900[1272] atgttccttt taaaaaaaat cactgattat gatgtgcctt ggtgtatttt tccttggttt 6960[1273] cttgtgcttg gaaatttttg aacttcttgg atctgtgggt ttattgtttc cataaaattt 7020[1274] ggaaattttt acaatcttct tcaaatattt tttctgatcc cccactctct cttcttcttt 7080[1275] ggagattctc attacaccta tattagcttg cttgaagttg tctcacagct cacttgtatt 7140[1276] ctgttgactt ttaaaaaatt atgctttctg tttcactgtg gatagtttct attgctacct 7200[1277] cttcaagttc actaatactt tccttttcaa tgtcaagact gctgtgaggc ccatccagtg 7260[1278] tactttgcat tttatacatt gtagttctaa aagttcggaa agttgttttt gggtcttttt 7320[1279] atatatgttc tgtgtctaac cttttaaaac ctggaacaca gatataacaa tggttttgat 7380[1280] gtccttgtct gcgaatctta tcacttgggt cagtttcagt tgatacctcc tcactgtggg 7440[1281] tcttgctccc ctggtgcttt ctgtgcctag taatttttgt cagatgccag atgtaacatt 7500[1282] taccttgttg ggtgctggat atttctgtat tcctgtaagt attctggagc tttgttatga 7560[1283] gttgcaggtt atttggaagc agtttccttt ttcaggtctt gctgttaaga ttcgttaggt 7620[1284] agaaccagag cagtgctcag tcaagggcta atgattgccc acccccaagg taaagagcct 7680[1285] cattgcactc tacccaattg cgttagtctg ttttgcagga atacctgagg ctgggtaatt 7740[1286] tatagagaaaagagttttat ttgg 7764[1287] <210>28

[1288] <211>3000

[1289] <212>DNA

[1290] <213>人

[1291] <400>28

[1292] ggcagcgtcc gcgggaggtg aggtggctgt ggggacccag gtggcctctt ccctggggcc 60[1293] ttgctaatga cggcaaaatc cgggttctgc caaaatatat ttaaaaaggt ttattcctag 120[1294] tcagtatgag tgactgtggc ccaggttatt cagcctcaag aggtcctgtg aaagtgcccg 180[1295] agatggtcag gcttgcaggt taattttata caattcaggg agacaggaat ttcaggtaaa 240[1296] gtcataaatc aggctgagca gtgtggctca tgcctgtggt cccagcactt tgggaggcca 300[1297] ggagttccag agcagcctgg gcagcacagc aagaccctgt ctctacatga aattagaaaa 360[1298] ataaaaaaat tagcggggcg tggtgtccca tgcctgtggc ctcagctact tgggaggccc 420[1299] agtcagttga gtccaggagg tggaggctgt aaccagctat gttggctgca ctgcacgcta 480[1300] gcctgggtaa cacagcgaga tcctgcctcc aaaaagaaaa tcataaatca ataagagaaa 540[1301] gatatacacg ggttcctccc aaaaagctgg tatatctcca aagggtttac acctcatggg 600[1302] ggcacttagg gattctttag tggacagttg gttgagagac ttaagctact gcctgaagac 660[1303] tggaatcaga agcatgccag agttaagggg attgcgtaga tcaaagttct tattatgtag 720[1304] atgaagcctc ttagttggca actctcagaa tagatggtaa atgtctgttt tcagtttttt 780[1305] gggtttttgt gtttttgttt ttgtttttag agagagtctt gctctgtcgc ccaggctaga 840[1306] gtgcagtggc gtgatctcag ctcactgcaa cctccacctc ccaggtttga gcggttctcc 900[1307] tgcctcggcc tcctgggtag ctgggactac gggcgcccgc caccacgcct ggctaatttt 960[1308] tgtattttta gtggagatgg ggtttcacca tgttgctgag gctggtcttg acttcctgac 1020[1309] ctcaggtgat ccgcccacct ctacctccca aagtgctggg attacaggcg tgggccaccg 1080[1310] cgcgtcaggc tggctgtctc ttccagacct aagaaaggct tagaacaaag gaggtctggc 1140[1311] tacattaatg gagattcgct gcagatgcaa attttcccac taaagatagc tttgcggggc 1200[1312] tatccatttc aatctgttgc ccctgtggca gccacttcaa aacatgtcaa agaagtatat 1260[1313] tttggggtaa aataatttcc ttcagcatct gctgtcatgt gatgctgtac cagagtcagg 1320[1314] ttggaaagtg agcctcatta tataagagta ataaaactca tctgatgaga ttttatggtt 1380[1315] tctcgggcag gattccccaa gcctcataca taggcatttg ggcaagggaa aaaaggtgaa 1440[1316] tttagtcctc accaggttgg tagggcttcc tcggttattg gagtgggagt aacagcaacc 1500[1317] attgggccca gcagtttttt taaatgtctc tggggctgtg gactgaccat ccaaataact 1560[1318] gattttaatc atttcattat ggaaaaattg tcagcagaac ccccaagtag agagacccat 1620[1319] cagtcaagat atacctcatg accttgcaag ctaatctagc ttgacccaga tcccctccta 1680[1320] atctgtgcag attcattgag gaatgtcata gccatgccta ctggttaaga catagtcctt 1740[1321] tacagtgaga gttgaaaccc aagctctatc actttcttgg ctgtgttgct ttgagaaagg 1800[1322] catttaaatg ttttgtgcct gtttcctcat ctgaaattgg tgggtaatag tcacttcata 1860[1323] ggacagttgt gaagattgaa tgcagaaaaa tttgtgccac gcctggaacc gtccctggca 1920[1324] tatattaaat tctaaaaaag tgttaaatat tataatgaat atcaacactt ccttattctg 1980[1325] gaagcaccga caggatatgc tgtgtttagt gttagcatca tgtcaggaca gggtctgttg 2040[1326] cgatgcccac actcaggatc tgttcccagg aacctgcgta aagttttctt ctctggaaga 2100[1327] ctttgggtcc ttttttttta acaagaagag gctctaccct gggactggga atttccaagg 2160[1328] ccacctttga ggatcgcaga gctcatttta gagccatttt agtccccagc tcctcttcct 2220[1329] ccactcccac gttacccgtg agaggactgt ctgcagggta agggaggaca gcccaacccc 2280[1330] aggtggggac ttcttatgta ttgccttcct gcagtgcctt ctctgcccta aaccatggtg 2340[1331] ggtttccttt gctaatgtct gacatcttgt gccctacact gtcccatctg aggctcagaa 2400[1332] cctctcagcc ggttctcatg gggaacgttc cccagatctg atgccctcat tcaggacact 2460[1333] tccatcattg tccctacatt tcttctctca gtgctttatt caggctgctg cattcgtggt 2520[1334] gcagaccagg tcttgtaaaa aattattcag tcagcatgtg ctgagccatt gtcctgtccc 2580[1335] agggacaggg ctttatagtc attgccctat tcatctcttc aaccaatgtg gaagttagga 2640[1336] attggaatcc ccatttcaca gactaagaag tggcgtgtta atcagttgaa ataattttta 2700[1337] cggcttggcg tggtggccca tacctgtaat cccagcactt tgggaggccg gggcgggcgg 2760[1338] attacctgag gccaggggtt cgagaccagc ctggccaaca tggtgaaacc tcatctctgc 2820[1339] tgggaataca gaaattagcc aggcatggtg gctcacgcct gtagtcccaa ctgctctgga 2880[1340] gcctgaagca ggataatcgc ttgaatccag gagatggagg ttgcagtgag cagagagcat 2940[1341] gccactgcac tacagcctga gcaagagtga gactccgtca caaaaaaaaa aaaaaaaaaa 3000[1342] <210>29

[1343] <211>489

[1344] <212>DNA

[1345] <213>人

[1346] <400>29

[1347] agagccgcag gtcagtcgtg aagagggagc tctattgcca ccatgagttt ctccggcaag 60[1348] taccaactgc agagccagga aaactttgaa gccttcatga aggcaatcgg tctgccggaa 120[1349] gagctcatcc agaaggggaa ggatatcaag ggggtgtcgg aaatcgtgca gaatgggaag 180[1350] cacttcaagt tcaccatcac cgctgggtcc aaagtgatcc aaaacgaatt cacggtgggg 240[1351] gaggaatgtg agctggagac aatgacaggg gagaaagtca agacagtggt tcagttggaa 300[1352] ggtgacaata aactggtgac aactttcaaa aacatcaagt ctgtgaccga actcaacggc 360[1353] gacataatca ccaataccat gacattgggt gacattgtct tcaagagaat cagcaagaga 420[1354] atttaaacaa gtctgcattt catattattt tagtgtgtaa aattaatgta ataaagtgaa 480[1355] ctttgtttt 489[1356] <210>30

[1357] <211>1699

[1358] <212>DNA

[1359] <213>人

[1360] <400>30

[1361] aggtgagcgg ttgctcgtcg tcggggcggc cggcagcggc ggctccaggg cccagcatgc 60[1362] gcgggggacc ccgcggccac catgtatgtg ggctatgtgc tggacaagga ttcgcccgtg 120[1363] taccccggcc cagccaggcc agccagcctc ggcctgggcc cggcaaacta cggccccccg 180[1364] gccccgcccc cggcgccccc gcagtacccc gacttctcca gctactctca cgtggagccg 240[1365] gcccccgcgc ccccgacggc ctggggggcg cccttccctg cgcccaagga cgactgggcc 300[1366] gccgcctacg gcccgggccc cgcggcccct gccgccagcc cagcttcgct ggcattcggg 360[1367] ccccctccag actttagccc ggtgccggcg ccccctgggc ccggcccggg cctcctggcg 420[1368] cagcccctcg ggggcccggg cacaccgtcc tcgcccggag cgcagaggcc gacgccctac 480[1369] gagtggatgc ggcgcagcgt ggcggccgga ggcggcggtg gcagcggtaa gactcggacc 540[1370] aaggacaagt accgcgtggt ctacaccgac caccaacgcc tggagctgga gaaggagttt 600[1371] cattacagcc gttacatcac aatccggcgg aaatcagagc tggctgccaa tctggggctc 660[1372] actgaacggc aggtgaagat ctggttccaa aaccggcggg caaaggagcg caaagtgaac 720[1373] aagaagaaac agcagcagca acagccccca cagccgccga tggcccacga catcacggcc 780[1374] accccagccg ggccatccct ggggggcctg tgtcccagca acaccagcct cctggccacc 840[1375] tcctctccaa tgcctgtgaa agaggagttt ctgccatagc cccatgccca gcctgtgcgc 900[1376] cgggggacct ggggactcgg gtgctgggag tgtggctcct gtgggcccag gaggtctggt 960[1377] ccgagtctca gccctgacct tctgggacat ggtggacagt cacctatcca ccctctgcat 1020[1378] ccccttggcc cattgtgtgc agtaagcctg ttggataaag accttccagc tcctgtgttc 1080[1379] tagacctctg ggggataagg gagtccaggg tggatgatct caatctcccg tgggcatctc 1140[1380] aagccccaaa tggttggggg aggggcctag acaaggctcc aggccccacc tcctcctcca 1200[1381] tacgttcaga ggtgcagctg gaggcctgtg tggggaccac actgatcctg gagaaaaggg 1260[1382] atggagctga aaaagatgga atgcttgcag agcatgacct gaggagggag gaacgtggtc 1320[1383] aactcacacc tgcctcttct gcagcctcac ctctacctgc ccccatcata agggcactga 1380[1384] gcccttccca ggctggatac taagcacaaa gcccatagca ctgggctctg atggctgctc 1440[1385] cactgggtta cagaatcaca gccctcatga tcattctcag tgagggctct ggattgagag 1500[1386] ggaggccctg ggaggagaga agggggcaga gtcttcccta ccaggtttct acacccccgc 1560[1387] caggctgccc atcagggccc agggagcccc cagaggactt tattcggacc aagcagagct 1620[1388] cacagctgga caggtgttgt atatagagtg gaatctcttg gatgcagctt caagaataaa 1680[1389] tttttcttct cttttcaaa 1699[1390] <210>31

[1391] <211>2612

[1392] <212>DNA

[1393] <213>人

[1394] <400>31

[1395] gctgatagca cagttctgtc cagagaagga aggcggaata aacttattca ttcccaggaa 60[1396] ctcttggggt aggtgtgtgt ttttcacatc ttaaaggctc acagaccctg cgctggacaa 120[1397] atgttccatt cctgaaggac ctctccagaa tccggattgc tgaatcttcc ctgttgccta 180[1398] gaagggctcc aaaccacctc ttgacaatgg gaaactgggt ggttaaccac tggttttcag 240[1399] ttttgtttct ggttgtttgg ttagggctga atgttttcct gtttgtggat gccttcctga 300[1400] aatatgagaa ggccgacaaa tactactaca caagaaaaat ccttgggtca acattggcct 360[1401] gtgcccgagc gtctgctctc tgcttgaatt ttaacagcac gctgatcctg cttcctgtgt 420[1402] gtcgcaatct gctgtccttc ctgaggggca cctgctcatt ttgcagccgc acactgagaa 480[1403] agcaattgga tcacaacctc accttccaca agctggtggc ctatatgatc tgcctacata 540[1404] cagctattca catcattgca cacctgttta actttgactg ctatagcaga agccgacagg 600[1405] ccacagatgg ctcccttgcc tccattctct ccagcctatc tcatgatgag aaaaaggggg 660[1406] gttcttggct aaatcccatc cagtcccgaa acacgacagt ggagtatgtg acattcacca 720[1407] gcgttgctgg tctcactgga gtgatcatga caatagcctt gattctcatg gtaacttcag 780[1408] ctactgagtt catccggagg agttattttg aagtcttctg gtatactcac caccttttta 840[1409] tcttctatat ccttggctta gggattcacg gcattggtgg aattgtccgg ggtcaaacag 900[1410] aggagagcat gaatgagagt catcctcgca agtgtgcaga gtcttttgag atgtgggatg 960[1411] atcgtgactc ccactgtagg cgccctaagt ttgaagggca tccccctgag tcttggaagt 1020[1412] ggatccttgc accggtcatt ctttatatct gtgaaaggat cctccggttt taccgctccc 1080[1413] agcagaaggt tgtgattacc aaggttgtta tgcacccatc caaagttttg gaattgcaga 1140[1414] tgaacaagcg tggcttcagc atggaagtgg ggcagtatat ctttgttaat tgcccctcaa 1200[1415] tctctctcct ggaatggcat ccttttactt tgacctctgc tccagaggaa gatttcttct 1260[1416] ccattcatat ccgagcagca ggggactgga cagaaaatct cataagggct ttcgaacaac 1320[1417] aatattcacc aattcccagg attgaagtgg atggtccctt tggcacagcc agtgaggatg 1380[1418] ttttccagta tgaagtggct gtgctggttg gagcaggaat tggggtcacc ccctttgctt 1440[1419] ctatcttgaa atccatctgg tacaaattcc agtgtgcaga ccacaacctc aaaacaaaaa 1500[1420] agatctattt ctactggatc tgcagggaga caggtgcctt ttcctggttc aacaacctgt 1560[1421] tgacttccct ggaacaggag atggaggaat taggcaaagt gggttttcta aactaccgtc 1620[1422] tcttcctcac cggatgggac agcaatattg ttggtcatgc agcattaaac tttgacaagg 1680[1423] ccactgacat cgtgacaggt ctgaaacaga aaacctcctt tgggagacca atgtgggaca 1740[1424] atgagttttc tacaatagct acctcccacc ccaagtctgt agtgggagtt ttcttatgtg 1800[1425] gccctcggac tttggcaaag agcctgcgca aatgctgtca ccgatattcc agtctggatc 1860[1426] ctagaaaggt tcaattctac ttcaacaaag aaaatttttg agttatagga ataaggacgg 1920[1427] taatctgcat tttgtctctt tgtatcttca gtaattgagt tataggaata aggacggtaa 1980[1428] tctgcatttt gtctctttgt atcttcagta atttacttgg tctcgtcagg tttgagcagt 2040[1429] cactttagga taagaatgtg cctctcaagc cttgactccc tggtattctt tttttgattg 2100[1430] cattcaactt cgttacttga gcttcagcaa cttaagaact tctgaagttc ttaaagttct 2160[1431] gaagttctta aagcccatgg atcctttctc agaaaaataa ctgtaaatct ttctggacag 2220[1432] ccatgactgt agcaaggctt gatagcagag gtttggtggt tcagagttat acaactaatc 2280[1433] ccaggtgatt ttatcaattc cagtgttacc atctcctgag ttttggtttg taatcttttg 2340[1434] tccctcccac ccccacagaa gatttcctaa gtag gtgac tttttaaata aaaatttatt 2400[1435] gaataattaa tgataaaaca taataataaa cataaataat aaacaaaatt accgagaacc 2460[1436] ccatccccat ataacaccaa cagtgtacat gtttactgtc acttttgata tggtcttatc 2520[1437] cagtgtgaac agcaatttat tatttttgct catcaaaaaa taaaggattt tttttcactt 2580[1438] gaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aa 2612[1439] <210>32

[1440] <211>3345

[1441] <212>DNA

[1442] <213>人

[1443] <400>32

[1444] gaattccgtc tcgaccactg aatggaagaa aaggactttt aaccaccatt ttgtgactta 60[1445] cagaaaggaa tttgaataaa gaaaactatg atacttcagg cccatcttca ctccctgtgt 120[1446] cttcttatgc tttatttggc aactggatat ggccaagagg ggaagtttag tggacccctg 180[1447] aaacccatga cattttctat ttatgaaggc caagaaccga gtcaaattat attccagttt 240[1448] aaggccaatc ctcctgctgt gacttttgaa ctaactgggg agacagacaa catatttgtg 300[1449] atagaacggg agggacttct gtattacaac agagccttgg acagggaaac aagatctact 360[1450] cacaatctcc aggttgcagc cctggacgct aatggaatta tagtggaggg tccagtccct 420[1451] atcaccatag aagtgaagga catcaacgac aatcgaccca cgtttctcca gtcaaagtac 480[1452] gaaggctcag taaggcagaa ctctcgccca ggaaagccct tcttgtatgt caatgccaca 540[1453] gacctggatg atccggccac tcccaatggc cagctttatt accagattgt catccagctt 600[1454] cccatgatca acaatgtcat gtactttcag atcaacaaca aaacgggagc catctctctt 660[1455] acccgagagg gatctcagga attgaatcct gctaagaatc cttcctataa tctggtgatc 720[1456] tcagtgaagg acatgggagg ccagagtgag aattccttca gtgataccac atctgtggat 780[1457] atcatagtga cagagaatat ttggaaagca ccaaaacctg tggagatggt ggaaaactca 840[1458] actgatcctc accccatcaa aatcactcag gtgcggtgga atgatcccgg tgcacaatat 900[1459] tccttagttg acaaagagaa gctgccaaga ttcccatttt caattgacca ggaaggagat 960[1460] atttacgtga ctcagccctt ggaccgagaa gaaaaggatg catatgtttt ttatgcagtt 1020[1461] gcaaaggatg agtacggaaa accactttca tatccgctgg aaattcatgt aaaagttaaa 1080[1462] gatattaatg ataatccacc tacatgtccg tcaccagtaa ccgtatttga ggtccaggag 1140[1463] aatgaacgac tgggtaacag tatcgggacc cttactgcac atgacaggga tgaagaaaat 1200[1464] actgccaaca gttttctaaa ctacaggatt gtggagcaaa ctcccaaact tcccatggat 1260[1465] ggactcttcc taatccaaac ctatgctgga atgttacagt tagctaaaca gtccttgaag 1320[1466] aagcaagata ctcctcagta caacttaacg atagaggtgt ctgacaaaga tttcaagacc 1380[1467] ctttgttttg tgcaaatcaa cgttattgat atcaatgatc agatccccat ctttgaaaaa 1440[1468] tcagattatg gaaacctgac tcttgctgaa gacacaaaca ttgggtccac catcttaacc 1500[1469] atccaggcca ctgatgctga tgagccattt actgggagtt ctaaaattct gtatcatatc 1560[1470] ataaagggag acagtgaggg acgcctgggg gttgacacag atccccatac caacaccgga 1620[1471] tatgtcataa ttaaaaagcc tcttgatttt gaaacagcag ctgtttccaa cattgtgttc 1680[1472] aaagcagaaa atcctgagcc tctagtgttt ggtgtgaagt acaatgcaag ttcttttgcc 1740[1473] aagttcacgc ttattgtgac agatgtgaat gaagcacctc aattttccca acacgtattc 1800[1474] caagcgaaag tcagtgagga tgtagctata ggcactaaag tgggcaatgt gactgccaag 1860[1475] gatccagaag gtctggacat aagctattca ctgaggggag acacaagagg ttggcttaaa 1920[1476] attgaccacg tgactggtga gatctttagt gtggctccat tggacagaga agccggaagt 1980[1477] ccatatcggg tacaagtggt ggccacagaa gtaggggggt cttccttaag ctctgtgtca 2040[1478] gagttccacc tgatccttat ggatgtgaat gacaaccctc ccaggctagc caaggactac 2100[1479] acgggcttgt tcttctgcca tcccctcagt gcacctggaa gtctcatttt cgaggctact 2160[1480] gatgatgatc agcacttatt tcggggtccc cattttacat tttccctcgg cagtggaagc 2220[1481] ttacaaaacg actgggaagt ttccaaaatc aatggtactc atgcccgact gtctaccagg 2280[1482] cacacagact ttgaggagag ggcgtatgtc gtcttgatcc gcatcaatga tgggggtcgg 2340[1483] ccacccttgg aaggcattgt ttctttacca gttacattct gcagttgtgt ggaaggaagt 2400[1484] tgtttccggc cagcaggtca ccagactggg atacccactg tgggcatggc agttggtata 2460[1485] ctgctgacca cccttctggt gattggtata attttagcag ttgtgtttat ccgcataaag 2520[1486] aaggataaag gcaaagataa tgttgaaagt gctcaagcat ctgaagtcaa acctctgaga 2580[1487] agctgaattt gaaaaggaat gtttgaattt atatagcaag tgctatttca gcaacaacca 2640[1488] tctcatccta ttacttttca tctaacgtgc attataattt tttaaacaga tattccctct 2700[1489] tgtcctttaa tatttgctaa atatttcttt tttgaggtgg agtcttgctc tgtcgcccag 2760[1490] gctggagtac agtggtgtga tcccagctca ctgcaacctc cgcctcctgg gttcacatga 2820[1491] ttctcctgcc tcagcttcct aagtagctgg gtttacaggc acccaccacc atgcccagct 2880[1492] aatttttgta tttttaatag agacggggtt tcgccatttg gccaggctgg tcttgaactc 2940[1493] ctgacgtcaa gtgatctgcc tgccttggtc tcccaataca ggcatgaacc actgcaccca 3000[1494] cctacttaga tatttcatgt gctatagaca ttagagagat ttttcatttt tccatgacat 3060[1495] ttttcctctc tgcaaatggc ttagctactt gtgtttttcc cttttggggc aagacagact 3120[1496] cattaaatat tctgtacatt ttttctttat caaggagata tatcagtgtt gtctcataga 3180[1497] actgcctgga ttccatttat gttttttctg attccatcct gtgtcccctt catccttgac 3240[1498] tcctttggta tttcactgaa tttcaaacat ttgtcagaga agaaaaaagt gaggactcag 3300[1499] gaaaaataaa taaataaaag aacagccttt tgcggccgcg aattc 3345[1500] <210>33

[1501] <211>1201

[1502] <212>DNA

[1503] <213>人

[1504] <220>

[1505] <221>misc_feature

[1506] <222>(532)..(532)

[1507] <223>w equals a or t

[1508] <400>33

[1509] wttatwahaa atttattttt aacccaatag aaaagcaaat ttggaatcta tttacaagta 60[1510] ctatatattt acatatatac agttagagtg ggagatttaa agaaaatggg cagagaaaca 120[1511] caatataaat caaagaatat gccactgtac aaggcattat tatcattatc atggtcctta 180[1512] atgttactga acctttacta tagtaataaa tacagttcta tatttacaca tcttataaaa 240[1513] catctcataa atgtattttt tcaaatccaa gthaaaacat ctgatcaaaa taaacatgct 300[1514] tatataaaaa taaatctacc taacagccat ttggtttgga tgtattgarg ctaatatagg 360[1515] ataatagagg gtaagrbtta atactttgac ttttcttatt taataacttg cttcttaaaa 420[1516] tacctaacac agtattaata tggaatargc rgagargtaa tgttcctaac atcaagtggg 480[1517] ttatccagag agaacacagc taaaaccaag ctaaataaac aggataatac gttactgagt 540[1518] ctcttgagtc caaagtggtg tcagatattg ggtttgccag agctactaga gatacatgtg 600[1519] tgagaggttg tatcagtgga cttaatttat gtgatgtgca catttgatca ttaagatgca 660[1520] catcagtttg aatcaactga taaaacttat tgcaaaaatt ctttactaac ccagaaaaaa 720[1521] aatcccagat tgcttacttt cttttccagg tatgtycatt gctggcagtg gaattccctt 780[1522] ctgagctttg ggcmcaagga gttaaaaaca aatcagataa gacatacgtc acctgtscat 840[1523] gattscctta gtaacaattt aagaattttg gtcagttttt ctttcaaaat acttgtaagc 900[1524] agttttatcc catgakggtg gaccatctag tgctgataca taaamctggt atctctaaaa 960[1525] wtgatctcaa tatgagtgag taacaatacy twacattacc ayctaaggga ttgtscttag 1020[1526] aaggatcttt cysmkkaags aaasgwggat haaaathtca awkktattwt attwatccaw 1080[1527] ttwaaaychm haaaataaat ttttattwaa ccawatttcy aatcccmaaa ccyttttttt 1140[1528] tttttaaaaa aattttatat tamcbkktcm tkyyktaaam dttttttaaa atttaaattw 1200[1529] a 1201[1530] <210>34

[1531] <211>2778

[1532] <212>DNA

[1533] <213>人

[1534] <400>34

[1535] ctcattttga tgtctagaat caggggatcc aggatcatca ccaaggtcat tttcccaggt 60[1536] atggaggggt ctttctgctt ctttcttgtc atgcacagct gctgaggaag gggctgggag 120[1537] taaagacagt gaaatgggga ggaggagtcc attcaaaccg agaaacaaag tgtttggttt 180[1538] ttcttacccc tggtgtagaa gctaccaacc ttttccaaga aagagggcct ggcccccttc 240[1539] tcgggtctgg ctgggtgcct gctgtgcctc tctggcctcc cctccgaagg gcaccattcc 300[1540] ctcgggtgag tactaccggc ctgcaccgtc ttccagtggg gacagcctga gaagagagtc 360[1541] tggggcctta cttcagtacc ttccttcact ggcctcaccc tgtgcaaatc atgccacacg 420[1542] ctgcagcctc cttttcccta tctataaaat aaaaatgacc ctgctctatc tcactgggct 480[1543] ggcaagaaca cactgttgtt gccttgcaga cagatgtgct gaggctgtag aaagtgcttt 540[1544] ttatttggtt gggagcttgt gcataaatgc gagaggggct gcacatctga cggactagag 600[1545] gtgactcatg gctgaaccgg aacaggacat cggggagaag ccagcagcca tgctgaactc 660[1546] tccacagggc cctgtgaaaa gctcttcacc tcctctgccc tctggatcta gtgaagccta 720[1547] ttcatccttc agatgtcagc tcaaataatc aaccttcatg gaggcctccc ttgaccccta 780[1548] acatgctttc aaagtactgt gtatttcaca ttcatcatgc cccgacaact gtgatttccc 840[1549] atttattaat atctgtctct tctgctggcc tgcaaactcc aggagcacag agacatcttt 900[1550] gggatttttg aacatgattt ccccagggct tagcccagtg cctggtgcaa agcaggcttt 960[1551] caacatgttc agtggatatt gtaagaaaga aagaaataca caaaaggcct ggcatatgca 1020[1552] aagcactcta aatattcact cctttccctt ccctctgggt gagaaaattt ctccttataa 1080[1553] agacaccctc ctaactgtat ctctgctaga gaactgaaga cataaagcac tctgtgccaa 1140[1554] aaatatttaa gtaaaaactt gagctaagca cagagattat aaatatttct tccccagatt 1200[1555] acgcaccatt taaaaatact gtctcagctc cttttcatga tttgggtggt gattaaagaa 1260[1556] aattactctt caagactgaa agtcattact gcccttttcc tgacttgcct tttcccttga 1320[1557] gaaggggagg ataagctgca gggcaggaag tggaagtggg gcatccttgt cctttgtctg 1380[1558] gcagacagcc aactggtcag gtactgctcc ttctcaactc tttcctgatt cccaggtgaa 1440[1559] tataaacaag aaggcacaaa tccacacttg ccaacaacgg acccaagtga taacaagaaa 1500[1560] cccagtgaca cctgtctagg tgaagactca gcccctatgt gaccaggttg caaagccaaa 1560[1561] ctgaccatct gctttccatt tggactttta gttcatactg tatcttctca ggacagttaa 1620[1562] gttggaatac aatgccactg tcctgaaaga tggtagaatt atcctatttc tggaggagtg 1680[1563] ggggtggtgg gtaggaatct caagagcgat ttgctcctct gcacaatagc ttctttaagg 1740[1564] acaccagggc ccccagggct atacatttcc ctgaagcttt ccagataagc aacaaggtat 1800[1565] gagcacctgc tatgtattgc ccaagggtga tgtgtttaaa tatccattgc atattttaaa 1860[1566] tccttggctg gcttaaagct gcaagctttc tgtcttcagt ggatataatg ggggcataca 1920[1567] tcccagagct tgcccaacac tccaagaaaa gaaccctcag ctaatgcaaa gtgtgtatgt 1980[1568] gcccatgaaa gctccatgtc tacttaacat tcagttttta ggattattta tgctgtaata 2040[1569] atagatatga aaatctctga caggtatttt gtttccttta caaactgtat ttgaatttat 2100[1570] gggtgattta gagcttgtgt ttaaagtcag aattcagaac cccaaagaaa atgacttcat 2160[1571] tgaaattgaa ctgaagagac aagaactgag ttaccaaaac ctactaaacg tgagttgctg 2220[1572] tgaactgggg attaaaccag aacgagtgga gaagatcaga aagctaccaa acacactgct 2280[1573] cagaaaggac aaagacattc gaagactgcg ggactttcag gaagtggaac tcattttaat 2340[1574] gaaaaatgga agctccagat tgacagaata tgtgccatct ctgacagaaa ggccctgcta 2400[1575] tgatagcaaa gctgcaaaaa tgacttatta aatactccca ggaatggccg cgcatggtgg 2460[1576] ctcaccccct gtaatcccag cactttggga agccaaggtg ggcggatcac ctgaggtcag 2520[1577] gagttctaga ccagcctggc caacatatag tgaaacccag tctctactaa aaaaaataca 2580[1578] aaaattagct aggtgtggtg gcgcacacct gtagtagtcc cagctacatg ggaagctgag 2640[1579] gcaggagaat cacctgaacc caggaggcag aggttgcagt gagctgagat tgcgccactg 2700[1580] cactccagcc tggcgacaga gcaagactct gtctctcaaa ataaataaat aaataaataa 2760[1581] ataaataaat aaataatc 2778[1582] <210>35

[1583] <211>2973

[1584] <212>DNA

[1585] <213>人

[1586] <400>35

[1587] attctggggc tcgggggatc ccggacaccc tctcagctcc tgcccggggg cccatgtagt 60[1588] cccttctgcc ctgtgcctcg gtgcctgtga cctgagcccc ttggttgacc ctgcactcgt 120[1589] ccaacttggg ccaaacgact gcccctcctt ctggcagtgg gctggaccag ccggccagcg 180[1590] ggagccccct tggcagaagc cggtcgtaaa ggatcataaa ctggcggcgt ctggctgggg 240[1591] cgaaggtcgc tgaggtagga actgcgccag tcctagacgc cagacccgct cagaccctcc 300[1592] tgccaggtga cagccgccaa gatggggtct tgggccctgc tgtggcctcc cctgctgttc 360[1593] accgggctgc tcgtccgacc cccggggacc atggcccagg cccagtactg ctctgtgaac 420[1594] aaggacatct ttgaagtaga ggagaacaca aatgtcaccg agccgctggt ggacatccac 480[1595] gtcccggagg gccaggaggt gaccctcgga gccttgtcca ccccctttgc atttcggatc 540[1596] cagggaaacc agctgtttct caacgtgact cctgattacg aggagaagtc actgcttgag 600[1597] gctcagctgc tgtgtcagag cggaggcaca ttggtgaccc agctaagggt gttcgtgtca 660[1598] gtgctggacg tcaatgacaa tgcccccgaa ttccccttta agaccaagga gataagggtg 720[1599] gaggaggaca cgaaagtgaa ctccaccgtc atccccgaga cgcaactgca ggctgaggac 780[1600] cgcgacaagg acgacattct gttctacacc ctccaggaaa tgacagcagg tgccagtgac 840[1601] tacttctccc tggtgagtgt aaaccgtccc gccctgaggc tggaccggcc cctggacttc 900[1602] tacgagcggc cgaacatgac cttctggctg ctggtgcggg acactccggg ggagaatgtg 960[1603] gaacccagcc acactgccac cgccacacta gtgctgaacg tggtgcccgc cgacctgcgg 1020[1604] cccccgtggt tcctgccctg caccttctca gatggctacg tctgcattca agctcagtac 1080[1605] cacggggctg tccccacggg gcacatactg ccatctcccc tcgtcctgcg tcccggaccc 1140[1606] atctacgctg aggacggaga ccgcggcatc aaccagccca tcatctacag catctttagg 1200[1607] ggaaacgtga atggtacatt catcatccac ccagactcgg gcaacctcac cgtggccagg 1260[1608] agtgtcccca gccccatgac cttccttctg ctggtgaagg gccaacaggc cgaccttgcc 1320[1609] cgctactcag tgacccaggt caccgtggag gctgtggctg cggccgggag cccgccccgc 1380[1610] ttcccccaga gcctgtatcg tggcaccgtg gcgcgtggcg ctggagcggg cgttgtggtc 1440[1611] aaggatgcag ctgccccttc tcagcctctg aggatccagg ctcaggaccc ggagttctcg 1500[1612] gacctcaact cggccatcac atatcgaatt accaaccact cacacttccg gatggaggga 1560[1613] gaggttgtgc tgaccaccac cacactggca caggcgggag ccttctacgc agaggttgag 1620[1614] gcccacaaca cggtgacctc tggcaccgca accacagtca ttgagataca agtttccgaa 1680[1615] caggagcccc cctccacaga tgtcccccca tccccagagg ctggaggaac aactgggccc 1740[1616] tggaccagca ccacttccga ggtccccaga ccccctgagc cctcccaggg accctccacg 1800[1617] accagctctg ggggaggcac aggccctcat ccaccctctg gcacaactct gaggccacca 1860[1618] acctcgtcca cacccggggg gtccccgggt gcagaaaaca gcacctccca ccaaccagcc 1920[1619] actcccggtg gggacacagc acagacccca aagccaggaa cctctcagcc gatgcccccc 1980[1620] ggtgtgggaa ccagcacctc ccaccaacca gccacaccca gtgggggcac agtacagacc 2040[1621] ccagagccag gaacctctca gccgatgccc cccagtatgg gaaccagcac ctcccaccaa 2100[1622] ccagccacac ccggtggggg cacagcacag accccagagg caggaacctc tcagccgatg 2160[1623] ccccccggta tgggaaccag cacctcccac caaccaacca cacccggtgg gggcacagca 2220[1624] cagaccccag agccaggaac ctctcagccg atgcccctca gcaagagcac cccatcttca 2280[1625] ggtggcggcc cctcggagga caagcgcttc tcggtggtgg atatggcggc cctgggcggg 2340[1626] gtgctgggtg cgctgctgct gctggctctc cttggcctcg ccgtccttgt ccacaagcac 2400[1627] tatggccccc ggctcaagtg ctgctctggc aaagctccgg agccccagcc ccaaggcttt 2460[1628] gacaaccagg cgttcctccc tgaccacaag gccaactggg cgcccgtccc cagccccacg 2520[1629] cacgacccca agcccgcgga ggcaccgatg cccgcagagc ccgcaccccc cggccctgcc 2580[1630] tccccaggcg gtgcccctga gccccccgca gcggcccgag ctggcggaag ccccacggcg 2640[1631] gtgaggtcca tcctgaccaa ggagcggcgg ccagagggcg ggtacaaggc tgtctggttt 2700[1632] ggcgaggaca tcgggacgga ggcagacgtg gtcgttctca acgcgcccac cctggacgtg 2760[1633] gatggcgcca gtgactccgg cagcggcgat gagggcgagg gcgcggggag gggtgggggt 2820[1634] ccctacgatg cgcccggtgg tgatgactcc tacatctaag tggcccctcc accctctccc 2880[1635] ccagccgcac gggcactgga ggtctcgctc ccccagcctc cgacccgagg cagaataaag 2940[1636] caaggctccc gaaacccaaa aaaaaaaaaa aaa 2973[1637] <210>36

[1638] <211>1930

[1639] <212>DNA

[1640] <213>人

[1641] <400>36

[1642] ggagagagag aggacagaga gcaagtcact cccggctgcc tttttcacct ctgacagagc 60[1643] ccagacacca tgaacgcaag tgaattccga aggagaggga aggagatggt ggattacgtg 120[1644] gccaactaca tggaaggcat tgagggacgc caggtctacc ctgacgtgga gcccgggtac 180[1645] ctgcggccgc tgatccctgc cgctgcccct caggagccag acacgtttga ggacatcatc 240[1646] aacgacgttg agaagataat catgcctggg gtgacgcact ggcacagccc ctacttcttc 300[1647] gcctacttcc ccactgccag ctcgtacccg gccatgcttg cggacatgct gtgcggggcc 360[1648] attggctgca tcggcttctc ctgggcggca agcccagcat gcacagagct ggagactgtg 420[1649] atgatggact ggctcgggaa gatgctggaa ctaccaaagg catttttgaa tgagaaagct 480[1650] ggagaagggg gaggagtgat ccagggaagt gccagtgaag ccaccctggt ggccctgctg 540[1651] gccgctcgga ccaaagtgat ccatcggctg caggcagcgt ccccagagct cacacaggcc 600[1652] gctatcatgg agaagctggt ggcttactca tccgatcagg cacactcctc agtggaaaga 660[1653] gctgggttaa ttggtggagt gaaattaaaa gccatcccct cagatggcaa cttcgccatg 720[1654] cgtgcgtctg ccctgcagga agccctggag agagacaaag cggctggcct gattcctttc 780[1655] tttatggttg ccaccctggg gaccacaaca tgctgctcct ttgacaatct cttagaagtc 840[1656] ggtcctatct gcaacaagga agacatatgg ctgcacgttg atgcagccta cgcaggcagt 900[1657] gcattcatct gccctgagtt ccggcacctt ctgaatggag tggagtttgc agattcattc 960[1658] aactttaatc cccacaaatg gctattggtg aattttgact gttctgccat gtgggtgaaa 1020[1659] aagagaacag acttaacggg agcctttaga ctggacccca cttacctgaa gcacagccat 1080[1660] caggattcag ggcttatcac tgactaccgg cattggcaga taccactggg cagaagattt 1140[1661] cgctctttga aaatgtggtt tgtatttagg atgtatggag tcaaaggact gcaggcttat 1200[1662] atccgcaagc atgtccagct gtcccatgag tttgagtcac tggtgcgcca ggatccccgc 1260[1663] tttgaaatct gtgtggaagt cattctgggg cttgtctgct ttcggctaaa gggttccaac 1320[1664] aaagtgaatg aagctcttct gcaaagaata aacagtgcca aaaaaatcca cttggttcca 1380[1665] tgtcacctca gggacaagtt tgtcctgcgc tttgccatct gttctcgcac ggtggaatct 1440[1666] gcccatgtgc agcgggcctg ggaacacatc aaagagctgg cggccgacgt gctgcgagca 1500[1667] gagagggagt aggagtgaag ccagctgcag gaatcaaaaa ttgaagagag atatatctga 1560[1668] aaactggaat aagaagcaaa taaatatcat cctgccttca tggaactcag ctgtctgtgg 1620[1669] cttcccatgt ctttctccaa agccatccag agggttgtga ttttgtctgc ttagtatctc 1680[1670] atcaacaaag aaatattatt tgctaattaa aaagttaatc ttcatggcca tagcttttat 1740[1671] tcattagctg tgatttttgt tgattaaaac attatagatt ttcatgttct tgcagtcatc 1800[1672] agaagtggta ggaaagcctc actgatatat tttccagggc aatcaatgtt cacgcaactt 1860[1673] gaaattatat ctgtggtctt caaattgtct tttgtcatgt ggctaaatgc ctaataaaca 1920[1674] attcaagtga 1930[1675] <210>37

[1676] <211>1745

[1677] <212>DNA

[1678] <213>人

[1679] <400>37

[1680] gcgcccctgg cagccttcaa cgtcggtccc caggcagcat ggtgaggtct gctcccggac 60[1681] cctcgccacc atgtacgtga gctacctcct ggacaaggac gtgagcatgt accctagctc 120[1682] cgtgcgccac tctggcggcc tcaacctggc gccgcagaac ttcgtcagcc ccccgcagta 180[1683] cccggactac ggcggttacc acgtggcggc cgcagctgca gcgcagaact tggacagcgc 240[1684] gcagtccccg gggccatcct ggccggcagc gtatggcgcc ccactccggg aggactggaa 300[1685] tggctacgcg cccggaggcg cggccgccgc caacgccgtg gctcacgcgc tcaacggtgg 360[1686] ctccccggcc gcagccatgg gctacagcag ccccgcagac taccatccgc accaccaccc 420[1687] gcatcaccac ccgcaccacc cggccgccgc gccttcctgc gcttctgggc tgctgcaaac 480[1688] gctcaacccc ggccctcctg ggcccgccgc caccgctgcc gccgagcagc tgtctcccgg 540[1689] cggccagcgg cggaacctgt gcgagtggat gcggaagccg gcgcagcagt ccctcggcag 600[1690] ccaagtgaaa accaggacga aagacaaata tcgagtggtg tacacggacc accagcggct 660[1691] ggagctggag aaggagtttc actacagtcg ctacatcacc atccggagga aagccgagct 720[1692] agccgccacg ctggggctct ctgagaggca ggttaaaatc tggtttcaga accgcagagc 780[1693] aaaggagagg aaaatcaaca agaagaagtt gcagcagcaa cagcagcagc agccaccaca 840[1694] gccgcctccg ccgccaccac agcctcccca gcctcagcca ggtcctctga gaagtgtccc 900[1695] agagcccttg agtccggtgt cttccctgca agcctcagtg tctggctctg tccctggggt 960[1696] tctggggcca actggggggg tgctaaaccc caccgtcacc cagtgaccca ccggggtctg 1020[1697] cagcggcaga gcaattccag gctgagccat gaggagcgtg gactctgcta gactcctcag 1080[1698] gagagacccc tcccctccca cccacagcca tagacctaca gacctggctc tcagaggaaa 1140[1699] aatgggagcc aggagtaaga caagtgggat ttggggcctc aagaaatata ctctcccaga 1200[1700] tttttacttt ttccatctgg ctttttctgc cactgaggag acagaaagcc tccgctgggc 1260[1701] ttcattccgg actggcagaa gcattgcctg gactgaccac accaaccagc ttcatctatc 1320[1702] cgactcttct cttcctagat ctgcaggctg cacctctggc tagagccgag gggagagagg 1380[1703] gactcaaggg aaaggcaagc ttgaggccaa gatggctgct gcctgctcat ggccctcgga 1440[1704] ggtccagctg ggcctcctgc ctccgggcag caaggtttac actgcggaac gcaaaggcag 1500[1705] ctaagataga aagctggact gaccaaagac tgcagaaccc ccaggtggcc ctgcgtcttt 1560[1706] tttctcttcc ctttcccaga ccaggaaagg cttggctggt gtatgcacag ggtgtggtat 1620[1707] gagggggtgg ttattggact ccaggcctga ccagggggcc cgaacaggac ttgttagaga 1680[1708] gcctgtcacc agagcttctc tgggctgaat gtatgtcagt gctataaatg ccagagccaa 1740[1709] cctgg 1745[1710] <210>38

[1711] <211>1881

[1712] <212>DNA

[1713] <213>人

[1714] <400>38

[1715] ggacctctcc agaatccgga ttgctgaatc ttccctgttg cctagaaggg ctccaaacca 60[1716] cctcttgaca atgggaaact gggtggttaa ccactggttt tcagttttgt ttctggttgt 120[1717] ttggttaggg ctgaatgttt tcctgtttgt ggatgccttc ctgaaatatg agaaggccga 180[1718] caaatactac tacacaagaa aaatccttgg gtcaacattg gcctgtgccc gagcgtctgc 240[1719] tctctgcttg aattttaaca gcacgctgat cctgcttcct gtgtgtcgca atctgctgtc 300[1720] cttcctgagg ggcacctgct cattttgcag ccgcacactg agaaagcaat tggatcacaa 360[1721] cctcaccttc cacaagctgg tggcctatat gatctgccta catacagcta ttcacatcat 420[1722] tgcacacctg tttaactttg actgctatag cagaagccga caggccacag atggctccct 480[1723] tgcctccatt ctctccagcc tatctcatga tgagaaaaag gggggttctt ggctaaatcc 540[1724] catccagtcc cgaaacacga cagtggagta tgtgacattc accagcattg ctggtctcac 600[1725] tggagtgatc atgacaatag ccttgattct catggtaact tcagctactg agttcatccg 660[1726] gaggagttat tttgaagtct tctggtatac tcaccacctt tttatcttct atatccttgg 720[1727] cttagggatt cacggcattg gtggaattgt ccggggtcaa acagaggaga gcatgaatga 780[1728] gagtcatcct cgcaagtgtg cagagtcttt tgagatgtgg gatgatcgtg actcccactg 840[1729] taggcgccct aagtttgaag ggcatccccc tgagtcttgg aagtggatcc ttgcaccggt 900[1730] cattctttat atctgtgaaa ggatcctccg gttttaccgc tcccagcaga aggttgtgat 960[1731] taccaaggtt gttatgcacc catccaaagt tttggaattg cagatgaaca agcgtggctt 1020[1732] cagcatggaa gtggggcagt atatctttgt taattgcccc tcaatctctc tcctggaatg 1080[1733] gcatcctttt actttgacct ctgctccaga ggaagatttc ttctccattc atatccgagc 1140[1734] agcaggggac tggacagaaa atctcataag ggctttcgaa caacaatatt caccaattcc 1200[1735] caggattgaa gtggatggtc cctttggcac agccagtgag gatgttttcc agtatgaagt 1260[1736] ggctgtgctg gttggagcag gaattggggt cacccccttt gcttctatct tgaaatccat 1320[1737] ctggtacaaa ttccagtgtg cagaccacaa cctcaaaaca aaaaagatct atttctactg 1380[1738] gatctgcagg gagacaggtg ccttttcctg gttcaacaac ctgttgactt ccctggaaca 1440[1739] ggagatggag gaattaggca aagtgggttt tctaaactac cgtctcttcc tcaccggatg 1500[1740] ggacagcaat attgttggtc atgcagcatt aaactttgac aaggccactg acatcgtgac 1560[1741] aggtctgaaa cagaaaacct cctttgggag accaatgtgg gacaatgagt tttctacaat 1620[1742] agctacctcc caccccaagt ctgtagtggg agttttctta tgtggccctc ggactttggc 1680[1743] aaagagcctg cgcaaatgct gtcaccgata ttccagtctg gatcctagaa aggttcaatt 1740[1744] ctacttcaac aaagaaaatt tttgagttat aggaataagg acggtaatct gcattttgtc 1800[1745] tctttgtatc ttcagtaatt tacttggtct cgtcaggttt gagcagtcac tttaggataa 1860[1746] gaatgtgcct ctcaagcctt g 1881[1747] <210>39

[1748] <211>3745

[1749] <212>DNA

[1750] <213>人

[1751] <400>39

[1752] cgcaaagcaa gtgggcacaa ggagtatggt tctaacgtga ttggggtcat gaagacgttg 60[1753] ctgttggact tggctttgtg gtcactgctc ttccagcccg ggtggctgtc ctttagttcc 120[1754] caggtgagtc agaactgcca caatggcagc tatgaaatca gcgtcctgat gatgggcaac 180[1755] tcagcctttg cagagcccct gaaaaacttg gaagatgcgg tgaatgaggg gctggaaata 240[1756] gtgagaggac gtctgcaaaa tgctggccta aatgtgactg tgaacgctac tttcatgtat 300[1757] tcggatggtc tgattcataa ctcaggcgac tgccggagta gcacctgtga aggcctcgac 360[1758] ctactcagga aaatttcaaa tgcacaacgg atgggctgtg tcctcatagg gccctcatgt 420[1759] acatactcca ccttccagat gtaccttgac acagaattga gctaccccat gatctcagct 480[1760] ggaagttttg gattgtcatg tgactataaa gaaaccttaa ccaggctgat gtctccagct 540[1761] agaaagttga tgtacttctt ggttaacttt tggaaaacca acgatctgcc cttcaaaact 600[1762] tattcctgga gcacttcgta tgtttacaag aatggtacag aaactgagga ctgtttctgg 660[1763] taccttaatg ctctggaggc tagcgtttcc tatttctccc acgaactcgg ctttaaggtg 720[1764] gtgttaagac aagataagga gtttcaggat atcttaatgg accacaacag gaaaagcaat 780[1765] gtgattatta tgtgtggtgg tccagagttc ctctacaagc tgaagggtga ccgagcagtg 840[1766] gctgaagaca ttgtcattat tctagtggat cttttcaatg accagtactt ggaggacaat 900[1767] gtcacagccc ctgactatat gaaaaatgtc cttgttctga cgctgtctcc tgggaattcc 960[1768] cttctaaata gctctttctc caggaatcta tcaccaacaa aacgagactt tgctcttgcc 1020[1769] tatttgaatg gaatcctgct ctttggacat atgctgaaga tatttcttga aaatggagaa 1080[1770] aatattacca cccccaaatt tgctcatgct ttcaggaatc tcacttttga agggtatgac 1140[1771] ggtccagtga ccttggatga ctggggggat gttgacagta ccatggtgct tctgtatacc 1200[1772] tctgtggaca ccaagaaata caaggttctt ttgacctatg atacccacgt aaataagacc 1260[1773] tatcctgtgg atatgagccc cacattcact tggaagaact ctaaacttcc taatgatatt 1320[1774] acaggccggg gccctcagat cctgatgatt gcagtcttca ccctcactgg agctgtggtg 1380[1775] ctgctcctgc tcgtcgctct cctgatgctc agaaaatata gaaaagatta tgaacttcgt 1440[1776] cagaaaaaat ggtcccacat tcctcctgaa aatatctttc ctctggagac caatgagacc 1500[1777] aatcatgtta gcctcaagat cgatgatgac aaaagacgag atacaatcca gagactacga 1560[1778] cagtgcaaat acgacaaaaa gcgagtgatt ctcaaagatc tcaagcacaa tgatggtaat 1620[1779] ttcactgaaa aacagaagat agaattgaac aagttgcttc agattgacta ttacaacctg 1680[1780] accaagttct acggcacagt gaaacttgat accatgatct tcggggtgat agaatactgt 1740[1781] gagagaggat ccctccggga agttttaaat gacacaattt cctaccctga tggcacattc 1800[1782] atggattggg agtttaagat ctctgtcttg tatgacattg ctaagggaat gtcatatctg 1860[1783] cactccagta agacagaagt ccatggtcgt ctgaaatcta ccaactgcgt agtggacagt 1920[1784] agaatggtgg tgaagatcac tgattttggc tgcaattcca ttttacctcc aaaaaaggac 1980[1785] ctgtggacag ctccagagca cctccgccaa gccaacatct ctcagaaagg agatgtgtac 2040[1786] agctatggga tcatcgcaca ggagatcatt ctgcggaaag aaaccttcta cactttgagc 2100[1787] tgtcgggacc ggaatgagaa gattttcaga gtggaaaatt ccaatggaat gaaacccttc 2160[1788] cgcccagatt tattcttgga aacagcagag gaaaaagagc tagaagtgta cctacttgta 2220[1789] aaaaactgtt gggaggaaga tccagaaaag agaccagatt tcaaaaaaat tgagactaca 2280[1790] cttgccaaga tatttggact ttttcatgac caaaaaaatg aaagctatat ggataccttg 2340[1791] atccgacgtc tacagctata ttctcgaaac ctggaacatc tggtagagga aaggacacag 2400[1792] ctgtacaagg cagagaggga cagggctgac agacttaact ttatgttgct tccaaggcta 2460[1793] gtggtaaagt ctctgaagga gaaaggcttt gtggagccgg aactatatga ggaagttaca 2520[1794] atctacttca gtgacattgt aggtttcact actatctgca aatacagcac ccccatggaa 2580[1795] gtggtggaca tgcttaatga catctataag agttttgacc acattgttga tcatcatgat 2640[1796] gtctacaagg tggaaaccat cggtgatgcg tacatggtgg ctagtggttt gcctaagaga 2700[1797] aatggcaatc ggcatgcaat agacattgcc aagatggcct tggaaatcct cagcttcatg 2760[1798] gggacctttg agctggagca tcttcctggc ctcccaatat ggattcgcat tggagttcac 2820[1799] tctggtccct gtgctgctgg agttgtggga atcaagatgc ctcgttattg tctatttgga 2880[1800] gatacggtca acacagcctc taggatggaa tccactggcc tccctttgag aattcacgtg 2940[1801] agtggctcca ccatagccat cctgaagaga actgagtgcc agttccttta tgaagtgaga 3000[1802] ggagaaacat acttaaaggg aagaggaaat gagactacct actggctgac tgggatgaag 3060[1803] gaccagaaat tcaacctgcc aacccctcct actgtggaga atcaacagcg tttgcaagca 3120[1804] gaattttcag acatgattgc caactcttta cagaaaagac aggcagcagg gataagaagc 3180[1805] caaaaaccca gacgggtagc cagctataaa aaaggcactc tggaatactt gcagctgaat 3240[1806] accacagaca aggagagcac ctatttttaa acctaaatga ggtataagga ctcacacaaa 3300[1807] ttaaaataca gctgcactga ggcagcgacc tcaagtgtcc tgaaagctta cattttcctg 3360[1808] agacctcaat gaagcagaaa tgtacttagg cttggctgcc ctgtctggaa catggacttt 3420[1809] cttgcatgaa tcagatgtgt gttctcagtg aaataactac cttccactct ggaaccttat 3480[1810] tccagcagtt gttccaggga gcttctacct ggaaaagaaa agaaatgaat agactatcta 3540[1811] gaacttgaga agattttatt cttatttcat ttattttttg tttgtttatt tttatcgttt 3600[1812] ttgtttactg gctttccttc tgtattcata agatttttta aattgtcata attatatttt 3660[1813] aaatacccat cttcattaaa gtatatttaa ctcataattt ttgcagaaaa tatgctatat 3720[1814] attaggcaag aataaaagct aaagg 3745[1815] <210>40

[1816] <211>2793

[1817] <212>DNA

[1818] <213>人

[1819] <400>40

[1820] ctaccccttt gtgagcagtc taggactttg tacacctgtt aagtagggag aaggcagggg 60[1821] aggtggctgg tttaagggga acttgaggga agtagggaag actcctcttg ggacctttgg 120[1822] agtaggtgac acatgagccc agccccagct cacctgccaa tccagctgag gagctcacct 180[1823] gccaatccag ctgaggctgg gcagaggtgg gtgagaagag ggaaaattgc agggacctcc 240[1824] agttgggcca ggccagaagc tgctgtagct ttaaccagac agctcagacc tgtctggagg 300[1825] ctgccagtga caggttaggt ttagggcaga gaagaagcaa gaccatggtg gggaagatgt 360[1826] ggcctgtgtt gtggacactc tgtgcagtca gggtgaccgt cgatgccatc tctgtggaaa 420[1827] ctccgcagga cgttcttcgg gcttcgcagg gaaagagtgt caccctgccc tgcacctacc 480[1828] acacttccac ctccagtcga gagggactta ttcaatggga taagctcctc ctcactcata 540[1829] cggaaagggt ggtcatctgg ccgttttcaa acaaaaacta catccatggt gagctttata 600[1830] agaatcgcgt cagcatatcc aacaatgctg agcagtccga tgcctccatc accattgatc 660[1831] agctgaccat ggctgacaac ggcacctacg agtgttctgt ctcgctgatg tcagacctgg 720[1832] agggcaacac caagtcacgt gtccgcctgt tggtcctcgt gccaccctcc aaaccagaat 780[1833] gcggcatcga gggagagacc ataattggga acaacatcca gctgacctgc caatcaaagg 840[1834] agggctcacc aacccctcag tacagctgga agaggtacaa catcctgaat caggagcagc 900[1835] ccctggccca gccagcctca ggtcagcctg tctccctgaa gaatatctcc acagacacat 960[1836] cgggttacta catctgtacc tccagcaatg aggaggggac gcagttctgc aacatcacgg 1020[1837] tggccgtcag atctccctcc atgaacgtgg ccctgtatgt gggcatcgcg gtgggcgtgg 1080[1838] ttgcagccct cattatcatt ggcatcatca tctactgctg ctgctgccga gggaaggacg 1140[1839] acaacactga agacaaggag gatgcaaggc cgaaccggga agcctatgag gagccaccag 1200[1840] agcagctaag agaactttcc agagagaggg aggaggagga tgactacagg caagaagagc 1260[1841] agaggagcac tgggcgtgaa tccccggacc acctcgacca gtgacaggcc agcagcagag 1320[1842] ggcggcggag gaagggttag gggttcattc tcccgcttcc tggcctccct tctcctttct 1380[1843] aagccctgtt ctcctgtccc tccatcccag acattgatgg ggacatttct tccccagtgt 1440[1844] cagctgtggg gaacatggct ggcctggtaa gggggtccct gtgctgatcc tgctgacctc 1500[1845] actgtcctgt gaagtaaccc ctcctggctg tgacacctgg tgcgggcctg gccctcactc 1560[1846] aagaccaggc tgcagcctcc acttccctcg tagttggcag gagctcctgg aagcacagcg 1620[1847] ctgagcatgg ggcgctccca ctcagaactc tccagggagg cgatgccagc cttggggggt 1680[1848] gggggctgtc ctgctcacct gtgtgcccag cacctggagg ggcaccaggt ggagggtttg 1740[1849] cactccacac atctttcttg aatgaatgaa agaataagtg agtatgcttg ggccctgcat 1800[1850] tggcctggcc tccagctccc actccctttc caacctcact tcccgtagct gccagtatgt 1860[1851] tccaaaccct cctgggaagg ccacctccca ctcctgctgc acaggccctg gggagctttt 1920[1852] gcccacacac tttccatctc tgcctgtcaa tatcgtacct gtccctccag gcccatctca 1980[1853] aatcacaagg atttctctaa ccctatccta attgtccaca tacgtggaaa caatcctgtt 2040[1854] actctgtccc acgtccaatc atgggccaca aggcacagtc ttctgagcga gtgctctcac 2100[1855] tgtattagag cgccagctcc ttggggcagg gcctgggcct catggctttt gctttccctg 2160[1856] aagccctagt agctggcgcc catcctagtg ggcacttaag cttaattggg gaaactgctt 2220[1857] tgattggttg tgccttccct tctctggtct ccttgagatg atcgtagaca cagggatgat 2280[1858] tcccacccaa acccacgtat tcattcagtg agttaaacac gaattgattt aaagtgaaca 2340[1859] cacacaaggg agcttgcttg cagatggtct gagttcttgt gtcctggtaa ttcctctcca 2400[1860] ggccagaata attggcatgt ctcctcaacc cacatggggt tcctggttgt tcctgcatcc 2460[1861] cgatacctca gccctggccc tgcccagccc atttgggctc tggttttctg gtggggctgt 2520[1862] cctgctgccc tcccacagcc tccttctgtt tgtcgagcat ttcttctact cttgagagct 2580[1863] caggcagcgt tagggctgct taggtctcat ggaccagtgg ctggtctcac ccaactgcag 2640[1864] tttactattg ctatcttttc tggatgatca gaaaaataat tccataaatc tattgtctac 2700[1865] ttgcgatttt ttaaaaaatg tatattttta tatatattgt taaatccttt gcttcattcc 2760[1866] aaatgctttc agtaataata aaattgtggg tgg 2793[1867] <210>41

[1868] <211>1734

[1869] <212>DNA

[1870] <213>人

[1871] <400>41

[1872] ggacctctcc agaatccgga ttgctgaatc ttccctgttg cctagaaggg ctccaaacca 60[1873] cctcttgaca atgggaaact gggtggttaa ccactggttt tcagttttgt ttctggttgt 120[1874] ttggttaggg ctgaatgttt tcctgtttgt ggatgccttc ctgaaatatg agaaggccga 180[1875] caaatactac tacacaagaa aaatccttgg gtcaacattg gcctgtgccc gagcgtctgc 240[1876] tctctgcttg aattttaaca gcacgctgat cctgcttcct gtgtgtcgca atctgctgtc 300[1877] cttcctgagg ggcacctgct cattttgcag ccgcacactg agaaagcaat tggatcacaa 360[1878] cctcaccttc cacaagctgg tggcctatat gatctgccta catacagcta ttcacatcat 420[1879] tgcacacctg tttaactttg actgctatag cagaagccga caggccacag atggctccct 480[1880] tgcctccatt ctctccagcc tatctcatga tgagaaaaag gggggttctt ggctaaatcc 540[1881] catccagtcc cgaaacacga cagtggagta tgtgacattc accagcattg ctggtctcac 600[1882] tggagtgatc atgacaatag ccttgattct catggtaact tcagctactg agttcatccg 660[1883] gaggagttat tttgaagtct tctggtatac tcaccacctt tttatcttct atatccttgg 720[1884] cttagggatt cacggcattg gtggaattgt ccggggtcaa acagaggaga gcatgaatga 780[1885] gagtcatcct cgcaagtgtg cagagtcttt tgagatgtgg gatgatcgtg actcccactg 840[1886] taggcgccct aagtttgaag ggcatccccc tgagtcttgg aagtggatcc ttgcaccggt 900[1887] cattctttat atctgtgaaa ggatcctccg gttttaccgc tcccagcaga aggttgtgat 960[1888] taccaaggtt gttatgcacc catccaaagt tttggaattg cagatgaaca agcgtggctt 1020[1889] cagcatggaa gtggggcagt atatctttgt taattgcccc tcaatctctc tcctggaatg 1080[1890] gcatcctttt actttgacct ctgctccaga ggaagatttc ttctccattc atatccgagc 1140[1891] agcaggggac tggacagaaa atctcataag ggctttcgaa caacaatatt caccaattcc 1200[1892] caggattgaa gtggatggtc cctttggcac agccagtgag gatgttttcc agtatgaagt 1260[1893] ggctgtgctg gttggagcag gaattggggt cacccccttt gcttctatct tgaaatccat 1320[1894] ctggtacaaa ttccagtgtg cagaccacaa cctcaaaaca aaaaaggttg gtcatgcagc 1380[1895] attaaacttt gacaaggcca ctgacatcgt gacaggtctg aaacagaaaa cctcctttgg 1440[1896] gagaccaatg tgggacaatg agttttctac aatagctacc tcccacccca agtctgtagt 1500[1897] gggagttttc ttatgtggcc ctcggacttt ggcaaagagc ctgcgcaaat gctgtcaccg 1560[1898] atattccagt ctggatccta gaaaggttca attctacttc aacaaagaaa atttttgagt 1620[1899] tataggaata aggacggtaa tctgcatttt gtctctttgt atcttcagta atttacttgg 1680[1900] tctcgtcagg tttgagcagt cactttagga taagaatgtg cctctcaagc cttg 1734[1901] <210>42

[1902] <211>3941

[1903] <212>DNA

[1904] <213>人

[1905] <400>42

[1906] accatctact ccacagtcag ctcatccaca actgccatca cctcaccttt cactaccgca 60[1907] gagactgggg tgacttccac accttcatcc ccatcttctc tgagtacaga catcccgacc 120[1908] acatccctaa gaactctcac cccattatct ttgagcacca gcacttcatt gactacaacc 180[1909] acagaccttc cctctatacc cactgatatc agtagcttac caaccccaat acacatcatt 240[1910] tcatcttctc cctccatcca aagtacagaa acctcatccc ttgtgggcac cacctctccc 300[1911] accatgtcca ctgtgagagc gaccctcaga agtactgaga acaccccaat cagttccttt 360[1912] agcacaagta ttgttgttac acctgaaacc ccaacaacac aggcccctcc tgtactgatg 420[1913] tctgccactg ggacccaaac atcccctgta cctactactg tcacctttgg aagtatggat 480[1914] tcctctacgt ccactcttca tactcttact ccatcaacag ccttgagcaa gatcatgtca 540[1915] acatcacagt ttcctattcc tagcacacat tcctccaccc ttcaaacaac tccttcaatc 600[1916] ccctctttgc aaacttcact cacatctaca agtgagttca ctacagaatc tttcactagg 660[1917] ggaagtacgt ctacaaatgc aatcttgact tcttttagta ccatcatctg gtcctcaaca 720[1918] cccactatta tcatgtcctc ttctccatct tctgccagca taactccagt gttcgctact 780[1919] accattcatt ctgttccttc gtcaccatac attttcagta cagaaaatgt gggctccgct 840[1920] tctatcacag cctttcctag tctctcttcc tcttcaacta ccagcacttc tccaaccagc 900[1921] tcctctctga ccacagctct cactgaaata accccctttt cttatatttc ccttccctcc 960[1922] accacaccct gtccaggaac tataacaatt accatagtcc ctgcctcccc cactgatcca 1020[1923] tgtgttgaaa tggatcccag cactgaagct acttctcctc ccaccactcc attaacagtc 1080[1924] tttcccttta ctactgaaat ggtcacctgt cctagctcca tcagtatgca aactactctt 1140[1925] gctacacata tggacacttc ttccatgacg ccagaaagtg agtccagcat catacctaat 1200[1926] gcttccagtt ccactggcac tgggactgta cccacaaaca cagttttcac aagtactcga 1260[1927] ctgcccacca gtgagacctg gctgagcaac aactctgtga tccccacacc tcttcctggc 1320[1928] gtctctacca tcccgctcac catgaaacca agcagtagcc tcccgaccat cctgaggact 1380[1929] tcaagcaagt caacacaccc atccccaccc accgccagga cttcagagac atcagtggcc 1440[1930] actacccaga ctcctaccac ccttacaacg cgcaggacaa ctcccatcac ttcttggatg 1500[1931] accacacagt ccacgttgac caccactgca ggcacctgtg acaatggtgg cacctgggaa 1560[1932] cagggccagt gtgcttgcct tccggggttt tctggggacc gctgtcagct ccagaccaga 1620[1933] tgccagaacg ggggccagtg ggatggcctc aagtgccagt gccccagcac cttctatggt 1680[1934] tccagttgtg agtttgctgt ggaacaggtg gatctagatg tagtggagac cgaggtgggc 1740[1935] atggaagtgt ctgtggatca gcagttctcg ccggacctca atgacaacac ttcccaggcc 1800[1936] tacagggatt tcaacaagac cttctggaat cagatgcaga agatttttgc agacatgcag 1860[1937] ggcttcacct tcaagggtgt ggagatcctg tccctgagga atggcagcat cgtggtggac 1920[1938] tacctggtcc tgctggagat gcccttcagc ccccagctgg agagcgagta tgagcaggtg 1980[1939] aagaccacgc tgaaggaggg gctccagaac gccagccagg atgcgaacag ctgccaggac 2040[1940] tcccagaccc tgtgttttaa gcctgactcc atcaaggtga acaacaacag caagacagag 2100[1941] ctgaccccgg aagccatctg ccgccgcgcc gctcccacgg gctatgaaga gttctacttc 2160[1942] cctctggtgg aggccacccg gctccgctgt gtcaccaaat gcacgtcggg cgtggacaac 2220[1943] gccatcgact gtcaccaggg ccagtgcgtt ctagagacga gcggtcccgc gtgtcgctgc 2280[1944] tactccaccg acacgcactg gttctctggc ccgcgctgcg aggtggccgt ccactggagg 2340[1945] gcgctggtcg ggggcctgac ggccggcgcc gcgctgctgg tgctgctgct gctggcgctg 2400[1946] ggcgtccggg cggtgcgctc cggatggtgg ggcggccagc gccgaggccg gtcctgggac 2460[1947] caggacagga aatggttcga gacctgggat gaggaagtcg tgggcacttt ttcaaactgg 2520[1948] ggtttcgagg acgacggaac agacaaggat acaaatttcc atgtggcctt ggagaacgtg 2580[1949] gacaccacta tgaaggtgca catcaagaga cccgagatga cctcgtcctc agtgtgagcc 2640[1950] ctgcggggcc ccttcaccac cccctccgcc ctgccccgga cacaagggtc tgcattgcgt 2700[1951] ccatttcaag aggtggcccc aggacgcggg cagcccaggc tcctgctgtt cttgggcaag 2760[1952] atgagactgt tcccccaaat cccatccttc tccttccaac ttggctgaaa cccacctgga 2820[1953] gacgcagttc acgtccaggc tcttccactg tggaatcttg ggcaagtcag taacgagcct 2880[1954] cagtttcctc acctgcaaaa cgggtacagc attcctgtat gatagctcac gccgttgttg 2940[1955] tgaaaaccac atagacttgg tcaattctcg gtcctactct gccctcccgt ctcagccctc 3000[1956] gtgttgccat tgcctctctc ggatcctcca atcctcacgt ccttcacctg gtctctggcc 3060[1957] ctggttctta ttttctctca attccctact gcctgtttct tactttgaac ctggaggcag 3120[1958] cctgcagccc catcccatct cctgccctct cctgatctaa ctccctgctg catctcttgc 3180[1959] tctcattcct tagacgtcct ccccttttga ccccgttcct tcatccatcc tgcaccccag 3240[1960] tcccccagcc ctaaatcctc cctcctctcc tcacatcctg gtccctagca aggtatagat 3300[1961] agcctctgtg tcttaggata ccccgggtgc tgttccctcg gtcaccctgt tgcccagttc 3360[1962] cccgtttctc ttgctctcat tccttgtatc ttctcccctt ctgagcccgt ccattcatcg 3420[1963] gttctgcccc cgactccccc agccctaaat accccagctc ctaattcccc cctcaccccg 3480[1964] ttgctcaatt ccccgtttct cttgctctca ttccttgtat cttctcccct tctgagcctg 3540[1965] tccattcatc ggtggttctg cccctactcc cccagcccta aataccccag ctgctgttcc 3600[1966] tccccatcac ccagccaccg gattctccat tcaccccttt ctctcacccc tggagccccg 3660[1967] tgggtggggg cagggcatga gttccccagt ccccaaggaa aggcagcccc ctcagtctcc 3720[1968] ctcctcctca ttcccttcca tctccctccc ctctgccttt taaacccatc ccctccgatt 3780[1969] cccctcctcc cccctctctc cctggtgtca actcgattcc tgcggtaact ctgagccctg 3840[1970] aaatcctcag tctccttggc ggggaagatt ggctttgggg acaggaagtc ggcacatctc 3900[1971] caggtctcca tgtgcacaat atagagttta ttgtaaaaag c 3941[1972] <210>43

[1973] <211>1126

[1974] <212>DNA

[1975] <213>人

[1976] <400>43

[1977] cagatactct gacccatgga tcccctgggc ccggccaagc cacagtggtc gtggcgctgc 60[1978] tgtctgacca cgctgctgtt tcagctgctg atggctgtgt gtttcttctc ctatctgcgt 120[1979] gtgtctcaag acgatcccac tgtgtaccct aatgggtccc gcttcccaga cagcacaggg 180[1980] acccccgccc actccatccc cctgatcctg ctgtggacgt ggccttttaa caaacccata 240[1981] gctctgcccc gctgctcaga gatggtgcct ggcacggctg actgcaacat cactgccgac 300[1982] cgcaaggtgt atccacaggc agacgcggtc atcgtgcacc accgagaggt catgtacaac 360[1983] cccagtgccc agctcccacg ctccccgagg cggcaggggc agcgatggat ctggttcagc 420[1984] atggagtccc caagccactg ctggcagctg aaagccatgg acggatactt caatctcacc 480[1985] atgtcctacc gcagcgactc cgacatcttc acgccctacg gctggctgga gccgtggtcc 540[1986] ggccagcctg cccacccacc gctcaacctc tcggccaaga ccgagctggt ggcctgggca 600[1987] gtgtccaact gggggccaaa ctccgccagg gtgcgctact accagagcct gcaggcccat 660[1988] ctcaaggtgg acgtgtacgg acgctcccac aagcccctgc cccagggaac catgatggag 720[1989] acgctgtccc ggtacaagtt ctatctggcc ttcgagaact ccttgcaccc cgactacatc 780[1990] accgagaagc tgtggaggaa cgccctggag gcctgggccg tgcccgtggt gctgggcccc 840[1991] agcagaagca actacgagag gttcctgccg cccgacgcct tcatccacgt ggacgacttc 900[1992] cagagcccca aggacctggc ccggtacctg caggagctgg acaaggacca cgcccgctac 960[1993] ctgagctact ttcgctggcg ggagacgctg cggcctcgct ccttcagctg ggcactcgct 1020[1994] ttctgcaagg cctgctggaa actgcaggag gaatccaggt accagacacg cggcatagcg 1080[1995] gcttggttca cctgagaggc ccggcatggg gcctgggctg ccaggg 1126[1996] <210>44

[1997] <211>6129

[1998] <212>DNA

[1999] <213>人

[2000] <400>44

[2001] aattggaagc aaatgacatc acagcaggtc agagaaaaag ggttgagcgg caggcaccca 60[2002] gagtagtagg tctttggcat taggagcttg agcccagacg gccctagcag ggaccccagc 120[2003] gcccgagaga ccatgcagag gtcgcctctg gaaaaggcca gcgttgtctc caaacttttt 180[2004] ttcagctgga ccagaccaat tttgaggaaa ggatacagac agcgcctgga attgtcagac 240[2005] atataccaaa tcccttctgt tgattctgct gacaatctat ctgaaaaatt ggaaagagaa 300[2006] tgggatagag agctggcttc aaagaaaaat cctaaactca ttaatgccct tcggcgatgt 360[2007] tttttctgga gatttatgtt ctatggaatc tttttatatt taggggaagt caccaaagca 420[2008] gtacagcctc tcttactggg aagaatcata gcttcctatg acccggataa caaggaggaa 480[2009] cgctctatcg cgatttatct aggcataggc ttatgccttc tctttattgt gaggacactg 540[2010] ctcctacacc cagccatttt tggccttcat cacattggaa tgcagatgag aatagctatg 600[2011] tttagtttga tttataagaa gactttaaag ctgtcaagcc gtgttctaga taaaataagt 660[2012] attggacaac ttgttagtct cctttccaac aacctgaaca aatttgatga aggacttgca 720[2013] ttggcacatt tcgtgtggat cgctcctttg caagtggcac tcctcatggg gctaatctgg 780[2014] gagttgttac aggcgtctgc cttctgtgga cttggtttcc tgatagtcct tgcccttttt 840[2015] caggctgggc tagggagaat gatgatgaag tacagagatc agagagctgg gaagatcagt 900[2016] gaaagacttg tgattacctc agaaatgatt gaaaatatcc aatctgttaa ggcatactgc 960[2017] tgggaagaag caatggaaaa aatgattgaa aacttaagac aaacagaact gaaactgact 1020[2018] cggaaggcag cctatgtgag atacttcaat agctcagcct tcttcttctc agggttcttt 1080[2019] gtggtgtttt tatctgtgct tccctatgca ctaatcaaag gaatcatcct ccggaaaata 1140[2020] ttcaccacca tctcattctg cattgttctg cgcatggcgg tcactcggca atttccctgg 1200[2021] gctgtacaaa catggtatga ctctcttgga gcaataaaca aaatacagga tttcttacaa 1260[2022] aagcaagaat ataagacatt ggaatataac ttaacgacta cagaagtagt gatggagaat 1320[2023] gtaacagcct tctgggagga gggatttggg gaattatttg agaaagcaaa acaaaacaat 1380[2024] aacaatagaa aaacttctaa tggtgatgac agcctcttct tcagtaattt ctcacttctt 1440[2025] ggtactcctg tcctgaaaga tattaatttc aagatagaaa gaggacagtt gttggcggtt 1500[2026] gctggatcca ctggagcagg caagacttca cttctaatga tgattatggg agaactggag 1560[2027] ccttcagagg gtaaaattaa gcacagtgga agaatttcat tctgttctca gttttcctgg 1620[2028] attatgcctg gcaccattaa agaaaatatc atctttggtg tttcctatga tgaatataga 1680[2029] tacagaagcg tcatcaaagc atgccaacta gaagaggaca tctccaagtt tgcagagaaa 1740[2030] gacaatatag ttcttggaga aggtggaatc acactgagtg gaggtcaacg agcaagaatt 1800[2031] tctttagcaa gagcagtata caaagatgct gatttgtatt tattagactc tccttttgga 1860[2032] tacctagatg ttttaacaga aaaagaaata tttgaaagct gtgtctgtaa actgatggct 1920[2033] aacaaaacta ggattttggt cacttctaaa atggaacatt taaagaaagc tgacaaaata 1980[2034] ttaattttga atgaaggtag cagctatttt tatgggacat tttcagaact ccaaaatcta 2040[2035] cagccagact ttagctcaaa actcatggga tgtgattctt tcgaccaatt tagtgcagaa 2100[2036] agaagaaatt caatcctaac tgagacctta caccgtttct cattagaagg agatgctcct 2160[2037] gtctcctgga cagaaacaaa aaaacaatct tttaaacaga ctggagagtt tggggaaaaa 2220[2038] aggaagaatt ctattctcaa tccaatcaac tctatacgaa aattttccat tgtgcaaaag 2280[2039] actcccttac aaatgaatgg catcgaagag gattctgatg agcctttaga gagaaggctg 2340[2040] tccttagtac cagattctga gcagggagag gcgatactgc ctcgcatcag cgtgatcagc 2400[2041] actggcccca cgcttcaggc acgaaggagg cagtctgtcc tgaacctgat gacacactca 2460[2042] gttaaccaag gtcagaacat tcaccgaaag acaacagcat ccacacgaaa agtgtcactg 2520[2043] gcccctcagg caaacttgac tgaactggat atatattcaa gaaggttatc tcaagaaact 2580[2044] ggcttggaaa taagtgaaga aattaacgaa gaagacttaa aggagtgcct ttttgatgat 2640[2045] atggagagca taccagcagt gactacatgg aacacatacc ttcgatatat tactgtccac 2700[2046] aagagcttaa tttttgtgct aatttggtgc ttagtaattt ttctggcaga ggtggctgct 2760[2047] tctttggttg tgctgtggct ccttggaaac actcctcttc aagacaaagg gaatagtact 2820[2048] catagtagaa ataacagcta tgcagtgatt atcaccagca ccagttcgta ttatgtgttt 2880[2049] tacatttacg tgggagtagc cgacactttg cttgctatgg gattcttcag aggtctacca 2940[2050] ctggtgcata ctctaatcac agtgtcgaaa attttacacc acaaaatgtt acattctgtt 3000[2051] cttcaagcac ctatgtcaac cctcaacacg ttgaaagcag gtgggattct taatagattc 3060[2052] tccaaagata tagcaatttt ggatgacctt ctgcctctta ccatatttga cttcatccag 3120[2053] ttgttattaa ttgtgattgg agctatagca gttgtcgcag ttttacaacc ctacatcttt 3180[2054] gttgcaacag tgccagtgat agtggctttt attatgttga gagcatattt cctccaaacc 3240[2055] tcacagcaac tcaaacaact ggaatctgaa ggcaggagtc caattttcac tcatcttgtt 3300[2056] acaagcttaa aaggactatg gacacttcgt gccttcggac ggcagcctta ctttgaaact 3360[2057] ctgttccaca aagctctgaa tttacatact gccaactggt tcttgtacct gtcaacactg 3420[2058] cgctggttcc aaatgagaat agaaatgatt tttgtcatct tcttcattgc tgttaccttc 3480[2059] atttccattt taacaacagg agaaggagaa ggaagagttg gtattatcct gactttagcc 3540[2060] atgaatatca tgagtacatt gcagtgggct gtaaactcca gcatagatgt ggatagcttg 3600[2061] atgcgatctg tgagccgagt ctttaagttc attgacatgc caacagaagg taaacctacc 3660[2062] aagtcaacca aaccatacaa gaatggccaa ctctcgaaag ttatgattat tgagaattca 3720[2063] cacgtgaaga aagatgacat ctggccctca gggggccaaa tgactgtcaa agatctcaca 3780[2064] gcaaaataca cagaaggtgg aaatgccata ttagagaaca tttccttctc aataagtcct 3840[2065] ggccagaggg tgggcctctt gggaagaact ggatcaggga agagtacttt gttatcagct 3900[2066] tttttgagac tactgaacac tgaaggagaa atccagatcg atggtgtgtc ttgggattca 3960[2067] ataactttgc aacagtggag gaaagccttt ggagtgatac cacagaaagt atttattttt 4020[2068] tctggaacat ttagaaaaaa cttggatccc tatgaacagt ggagtgatca agaaatatgg 4080[2069] aaagttgcag atgaggttgg gctcagatct gtgatagaac agtttcctgg gaagcttgac 4140[2070] tttgtccttg tggatggggg ctgtgtccta agccatggcc acaagcagtt gatgtgcttg 4200[2071] gctagatctg ttctcagtaa ggcgaagatc ttgctgcttg atgaacccag tgctcatttg 4260[2072] gatccagtaa cataccaaat aattagaaga actctaaaac aagcatttgc tgattgcaca 4320[2073] gtaattctct gtgaacacag gatagaagca atgctggaat gccaacaatt tttggtcata 4380[2074] gaagagaaca aagtgcggca gtacgattcc atccagaaac tgctgaacga gaggagcctc 4440[2075] ttccggcaag ccatcagccc ctccgacagg gtgaagctct ttccccaccg gaactcaagc 4500[2076] aagtgcaagt ctaagcccca gattgctgct ctgaaagagg agacagaaga agaggtgcaa 4560[2077] gatacaaggc tttagagagc agcataaatg ttgacatggg acatttgctc atggaattgg 4620[2078] agctcgtggg acagtcacct catggaattg gagctcgtgg aacagttacc tctgcctcag 4680[2079] aaaacaagga tgaattaagt ttttttttaa aaaagaaaca tttggtaagg ggaattgagg 4740[2080] acactgatat gggtcttgat aaatggcttc ctggcaatag tcaaattgtg tgaaaggtac 4800[2081] ttcaaatcct tgaagattta ccacttgtgt tttgcaagcc agattttcct gaaaaccctt 4860[2082] gccatgtgct agtaattgga aaggcagctc taaatgtcaa tcagcctagt tgatcagctt 4920[2083] attgtctagt gaaactcgtt aatttgtagt gttggagaag aactgaaatc atacttctta 4980[2084] gggttatgat taagtaatga taactggaaa cttcagcggt ttatataagc ttgtattcct 5040[2085] ttttctctcc tctccccatg atgtttagaa acacaactat attgtttgct aagcattcca 5100[2086] actatctcat ttccaagcaa gtattagaat accacaggaa ccacaagact gcacatcaaa 5160[2087] atatgcccca ttcaacatct agtgagcagt caggaaagag aacttccaga tcctggaaat 5220[2088] cagggttagt attgtccagg tctaccaaaa atctcaatat ttcagataat cacaatacat 5280[2089] cccttacctg ggaaagggct gttataatct ttcacagggg acaggatggt tcccttgatg 5340[2090] aagaagttga tatgcctttt cccaactcca gaaagtgaca agctcacaga cctttgaact 5400[2091] agagtttagc tggaaaagta tgttagtgca aattgtcaca ggacagccct tctttccaca 5460[2092] gaagctccag gtagagggtg tgtaagtaga taggccatgg gcactgtggg tagacacaca 5520[2093] tgaagtccaa gcatttagat gtataggttg atggtggtat gttttcaggc tagatgtatg 5580[2094] tacttcatgc tgtctacact aagagagaat gagagacaca ctgaagaagc accaatcatg 5640[2095] aattagtttt atatgcttct gttttataat tttgtgaagc aaaatttttt ctctaggaaa 5700[2096] tatttatttt aataatgttt caaacatata ttacaatgct gtattttaaa agaatgatta 5760[2097] tgaattacat ttgtataaaa taatttttat atttgaaata ttgacttttt atggcactag 5820[2098] tatttttatg aaatattatg ttaaaactgg gacaggggag aacctagggt gatattaacc 5880[2099] aggggccatg aatcaccttt tggtctggag ggaagccttg gggctgatcg agttgttgcc 5940[2100] cacagctgta tgattcccag ccagacacag cctcttagat gcagttctga agaagatggt 6000[2101] accaccagtc tgactgtttc catcaagggt acactgcctt ctcaactcca aactgactct 6060[2102] taagaagact gcattatatt tattactgta agaaaatatc acttgtcaat aaaatccata 6120[2103] catttgtgt 6129[2104] <210>45

[2105] <211>330

[2106] <212>DNA

[2107] <213>人

[2108] <400>45

[2109] gcggccgcag gtacccgggc tccacgtcag ggtagacctg gcgtccctca atgccttcca 60[2110] tgtagttggc cacgtaatcc accatctcct tccctctcct tcggaattca cttgcgttca 120[2111] tggtgtctgg gctctgtcag aggtgaaaaa tgctggaaat tcgaattcct tacagggcta 180[2112] ctctccttga tgggattctc caactttggg gactgaagag catgtggaga agctgctgag 240[2113] gcactcggca ctgagacagt cactcttctt gaaactccaa gccacacgtt tccctcttct 300[2114] tgcatttcca gccacatgtg cccctcgtgc 330[2115] <210>46

[2116] <211>2400

[2117] <212>DNA

[2118] <213>人

[2119] <400>46

[2120] ctgtagggga ggatattttg attgaacaca ggcttgacag aatcttcttt tcttcttaga 60[2121] aatcctagaa aacagaaagc aacaggaaga tgtcttattg ggaactaccc ccatcaactt 120[2122] caccatgagt caaacaagga agaaaacttc ctcagaagga gaaactaagc cccagacttc 180[2123] aactgtcaac aaatttctca ggggctccaa tgctgaaagc agaaaagagg acaatgacct 240[2124] taaaacaagt gattcccaac ccagcgactg gatacagaag acagccacct cagagactgc 300[2125] taagcctctc agttcagaaa tggaatggag atccagtatg gagaaaaatg agcatttcct 360[2126] gcagaagctg ggcaaaaagg ctgtcaacaa gtgtctagat ttgaataact gtggattaac 420[2127] aacagcggac atgaaagaaa tgggagaagc atttgagatg attcctgaac ttgaagagct 480[2128] aaatttgtct tggaacagta aagtgggagg aaatttgcct ctgatccttc agaagttcca 540[2129] aaaagggagc aagatacaaa tgattgagct tgtggattgc tccctcacgt cagaagatgg 600[2130] gacatttctg ggtcaactgc tacctatgct gcaaagtctc gaagtacttg atctttccat 660[2131] taacagagac attgttggca gtctgaacag tattgctcag ggattaaaaa gcacctcaaa 720[2132] tctgaaagta ctgaagttac attcatgtgg attatcacaa aagagtgtca aaatattgga 780[2133] tgctgctttt aggtatttgg gtgagctgag gaaattagat ctttcctgca ataaggatct 840[2134] aggtggaggt tttgaagact cgccggctca gttggtcatg ctaaagcatc tacaagtcct 900[2135] agatcttcac cagtgctcac taacagcaga tgacgtgatg tcactgaccc aggtcattcc 960[2136] tttactttca aatcttcaag aattggattt atcagccaac aaaaagatgg gcagttcttc 1020[2137] tgaaaactta ctcagcaggc tccgattttt accagcattg aagtcattag ttatcaacaa 1080[2138] ctgtgctttg gagagtgaga cttttacagc tcttgctgaa gcctctgttc acctctctgc 1140[2139] tctggaagta ttcaaccttt cttggaacaa gtgtgttggt ggcaacttgg agctgcttct 1200[2140] ggaaacacta aagctttcca tgtctcttca agtgctgagg ctgagcagct gttccctggt 1260[2141] gacagaggat gtggctctcc tggcatcggt catacagacg ggtcatctgg ccaaactgca 1320[2142] aaagctggac ctgagctaca atgacagcat ctgtgatgca gggtggacca tgttctgcca 1380[2143] aaacgtgcgg ttcctcaaag agctaatcga gctggatatt agccttcgac catcaaattt 1440[2144] tcgagattgt ggacaatggt ttagacactt gttatatgct gtgaccaagc ttcctcagat 1500[2145] cactgagata ggaatgaaaa gatggattct cccagcttca caggaggaag aactagaatg 1560[2146] ctttgaccaa gaaaaaaaaa agaagcattc actttgacca tggtgggttt cagtaaactg 1620[2147] atttcccatg tcctactaag ctacaaacca ttctccaaag gaaaagaaca tgaacgaatt 1680[2148] ccagagtcat gaactgaatt tcaacttctg ggccatttaa tgggacttat attacaagag 1740[2149] ctttgtaaat atatatatat attacatata tatatgtaat atacatatat acacatatat 1800[2150] ataatataca tatataatac acatatatat gtaaatatat atataatatc taatatgagc 1860[2151] atgccattat tctctgtcta tgaaacaaaa atggcatttt tcaatggatt tgttttggat 1920[2152] atataattag ttcatttgct gtttagaagc cttgccaaaa gtgtttagat tttggtactg 1980[2153] caactgcttt cctcttgccc agaaatgttt tgcctcttct tttcctacaa gttaaatgtt 2040[2154] ctaaatataa aggggtatgt gtgtgtgtgt gtaattctaa tgtgaaaggc actagctgtc 2100[2155] taatagtttc atgtatcatt actattacta tatgtatctt aatgtagtct atgtaggttt 2160[2156] ttatcagaaa gtgtaccttt ctatggttta ttattttata ttctggtgcc ttttatctca 2220[2157] gatataaacc atgaacagta atgatagtca ctgacatata aatcttagta aaaagtgatt 2280[2158] aaaaatctaa aactcagtat gaaaaacata tcttgttaga ataaattaaa accttttatt 2340[2159] gtttaaaaaa ttgttaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 2400[2160] <210>47

[2161] <211>2308

[2162] <212>DNA

[2163] <213>人

[2164] <400>47

[2165] aagccacttt gacaacgttt ctgagccagg ggtgaccatg acctgctgcg aaggatggac 60[2166] atcctgcaat ggattcagcc tgctggttct actgctgtta ggagtagttc tcaatgtgat 120[2167] acctctaatt gtcagcttag ttgaggaaga ccaattttct caaaacccca tctcttgctt 180[2168] tgagtggtgg ttcccaggaa ttataggagc aggtctgatg gccattccag caacaacaat 240[2169] gtccttgaca gcaagaaaaa gagcgtgctg caacaacaga actggaatgt ttctttcatc 300[2170] acttttcagt gtgatcacag tcattggtgc tctgtattgc atgctgatat ccatccaggc 360[2171] tctcttaaaa ggtcctctca tgtgtaattc tccaagcaac agtaatgcca attgtgaatt 420[2172] ttcattgaaa aacatcagtg acattcatcc agaatccttc aacttgcagt ggtttttcaa 480[2173] tgactcttgt gcacctccta ctggtttcaa taaacccacc agtaacgaca ccatggcgag 540[2174] tggctggaga gcatctagtt tccacttcga ttctgaagaa aacaaacata ggcttatcca 600[2175] cttctcagta tttttaggtc tattgcttgt tggaattctg gaggtcctgt ttgggctcag 660[2176] tcagatagtc atcggtttcc ttggctgtct gtgtggagtc tctaagcgaa gaagtcaaat 720[2177] tgtgtagttt aatgggaata aaatgtaagt atcagtagtt tgaattaatt tgagaagtac 780[2178] acttgttttc aaagtcatct ttgagatgat ttaaaaaatc aacccttcac gtagaaagca 840[2179] cgttgtaaat gcataacact ctcatatcag tggttgattt gggaaaggtg gagagaattt 900[2180] tcaattagtt ttgtgttgta ctattcaaat tttttacctc ttcactgtgt gtagagaaag 960[2181] gagaagggaa ggaggatgag aaggaacgga agtcatcctg aaaataaaag tacaggactt 1020[2182] tttttttttt tttttgagac agggtctcaa aaaaggctgg agtacagtag tacagtggtg 1080[2183] ctatctcagc ttactgcagc ctcaacctcc tgggctcagg tgattctccc atctcagcct 1140[2184] ccctagtagc tgggactaca ggtgcgtgcc actatgccaa gctaattttt gtatttttag 1200[2185] tagagatggg ggttttccat attgcccagg ctggtcccga actcatggac tcaagtgatc 1260[2186] tgcctgcctc agcctcctaa agtgctgcga ttacaggcat gagccatcgc gcctaaagga 1320[2187] caggaccttt ttattgtatt tctttaaaga ataaatacat aacctgaatg caatcaagtc 1380[2188] tttagatcta attctcagct tgcagggaac actaggacaa atccaaaaag tgggtcagcg 1440[2189] ggcacagaat ggcccaattt tcaacaggaa aatgttataa aagaaaaata tttttgaggg 1500[2190] aactgttata gattaagaga atagaggcat gtttcagcta aacacatgta aactttgtca 1560[2191] gagataattg ggaggagtat gtagaagaat cggattattg ttaattttgg taggtctgat 1620[2192] aatggtttta tagtataaag gctgagtacc ccttatccaa aatgattaag atcagaagtg 1680[2193] ttttggcttt cacatttttt tggattttgg aattttgcct ataataatga gacatcttgg 1740[2194] ggatgggatg caagtctaac cacaaaattc atttatgtct catacacact ttgaacacct 1800[2195] ggcctgaagg taatttcaca caatatttta aataactttg tgcatgaaac acaattttga 1860[2196] ctgcattttg actgcaactc atcacatgag gtcaggtatg gaattttcca cttgtggtgt 1920[2197] tacgttactg gctcaaaaag ttttggatct cggagcattc tggattttga atttttggat 1980[2198] tagtgatgct caacctgtat acagaaatgt cctcattttt aaaaaaagaa atgcatattt 2040[2199] atatgtttta aaattacttc aaccaaaagc aacggggaga tgtttactgt tatatttagg 2100[2200] tgacaggtac atggcaattc attataccct cctattttcc tatgtttaca ttattcatta 2160[2201] attaaaaaac aatacctaga aaaacccaag actttcaaaa gctattttct atatgtgcca 2220[2202] atctttaaaa aacaggataa caagggtatt tatcacatta aaatgttgta aaacagcaaa 2280[2203] gctaaaatct aaaaaaaaaa aaaaaaaa 2308[2204] <210>48

[2205] <211>2880

[2206] <212>DNA

[2207] <213>人

[2208] <400>48

[2209] tgctgctctc cgcccgcgtc cggctcgtgg ccccctactt cgggcaccat ggacacctcc 60[2210] cggctcggtg tgctcctgtc cttgcctgtg ctgctgcagc tggcgaccgg gggcagctct 120[2211] cccaggtctg gtgtgttgct gaggggctgc cccacacact gtcattgcga gcccgacggc 180[2212] aggatgttgc tcagggtgga ctgctccgac ctggggctct cggagctgcc ttccaacctc 240[2213] agcgtcttca cctcctacct agacctcagt atgaacaaca tcagtcagct gctcccgaat 300[2214] cccctgccca gtctccgctt cctggaggag ttacgtcttg cgggaaacgc tctgacatac 360[2215] attcccaagg gagcattcac tggcctttac agtcttaaag ttcttatgct gcagaataat 420[2216] cagctaagac acgtacccac agaagctctg cagaatttgc gaagccttca atccctgcgt 480[2217] ctggatgcta accacatcag ctatgtgccc ccaagctgtt tcagtggcct gcattccctg 540[2218] aggcacctgt ggctggatga caatgcgtta acagaaatcc ccgtccaggc ttttagaagt 600[2219] ttatcggcat tgcaagccat gaccttggcc ctgaacaaaa tacaccacat accagactat 660[2220] gcctttggaa acctctccag cttggtagtt ctacatctcc ataacaatag aatccactcc 720[2221] ctgggaaaga aatgctttga tgggctccac agcctagaga ctttagattt aaattacaat 780[2222] aaccttgatg aattccccac tgcaattagg acactctcca accttaaaga actaggattt 840[2223] catagcaaca atatcaggtc gatacctgag aaagcatttg taggcaaccc ttctcttatt 900[2224] acaatacatt tctatgacaa tcccatccaa tttgttggga gatctgcttt tcaacattta 960[2225] cctgaactaa gaacactgac tctgaatggt gcctcacaaa taactgaatt tcctgattta 1020[2226] actggaactg caaacctgga gagtctgact ttaactggag cacagatctc atctcttcct 1080[2227] caaaccgtct gcaatcagtt acctaatctc caagtgctag atctgtctta caacctatta 1140[2228] gaagatttac ccagtttttc agtctgccaa aagcttcaga aaattgacct aagacataat 1200[2229] gaaatctacg aaattaaagt tgacactttc cagcagttgc ttagcctccg atcgctgaat 1260[2230] ttggcttgga acaaaattgc tattattcac cccaatgcat tttccacttt gccatcccta 1320[2231] ataaagctgg acctatcgtc caacctcctg tcgtcttttc ctataactgg gttacatggt 1380[2232] ttaactcact taaaattaac aggaaatcat gccttacaga gcttgatatc atctgaaaac 1440[2233] tttccagaac tcaaggttat agaaatgcct tatgcttacc agtgctgtgc atttggagtg 1500[2234] tgtgagaatg cctataagat ttctaatcaa tggaataaag gtgacaacag cagtatggac 1560[2235] gaccttcata agaaagatgc tggaatgttt caggctcaag atgaacgtga ccttgaagat 1620[2236] ttcctgcttg actttgagga agacctgaaa gcccttcatt cagtgcagtg ttcaccttcc 1680[2237] ccaggcccct tcaaaccctg tgaacacctg cttgatggct ggctgatcag aattggagtg 1740[2238] tggaccatag cagttctggc acttacttgt aatgctttgg tgacttcaac agttttcaga 1800[2239] tcccctctgt acatttcccc cattaaactg ttaattgggg tcatcgcagc agtgaacatg 1860[2240] ctcacgggag tctccagtgc cgtgctggct ggtgtggatg cgttcacttt tggcagcttt 1920[2241] gcacgacatg gtgcctggtg ggagaatggg gttggttgcc atgtcattgg ttttttgtcc 1980[2242] atttttgctt cagaatcatc tgttttcctg cttactctgg cagccctgga gcgtgggttc 2040[2243] tctgtgaaat attctgcaaa atttgaaacg aaagctccat tttctagcct gaaagtaatc 2100[2244] attttgctct gtgccctgct ggccttgacc atggccgcag ttcccctgct gggtggcagc 2160[2245] aagtatggcg cctcccctct ctgcctgcct ttgccttttg gggagcccag caccatgggc 2220[2246] tacatggtcg ctctcatctt gctcaattcc ctttgcttcc tcatgatgac cattgcctac 2280[2247] accaagctct actgcaattt ggacaaggga gacctggaga atatttggga ctgctctatg 2340[2248] gtaaaacaca ttgccctgtt gctcttcacc aactgcatcc taaactgccc tgtggctttc 2400[2249] ttgtccttct cctctttaat aaaccttaca tttatcagtc ctgaagtaat taagtttatc 2460[2250] cttctggtgg tagtcccact tcctgcatgt ctcaatcccc ttctctacat cttgttcaat 2520[2251] cctcacttta aggaggatct ggtgagcctg agaaagcaaa cctacgtctg gacaagatca 2580[2252] aaacacccaa gcttgatgtc aattaactct gatgatgtcg aaaaacagtc ctgtgactca 2640[2253] actcaagcct tggtaacctt taccagctcc agcatcactt atgacctgcc tcccagttcc 2700[2254] gtgccatcac cagcttatcc agtgactgag agctgccatc tttcctctgt ggcatttgtc 2760[2255] ccatgtctct aattaatatg tgaaggaaaa tgttttcaaa ggttgagaac ctgaaaatgt 2820[2256] gagattgagt atatcagagc agtaattaat aagaagagct gaggtgaaac tcggtttaaa 2880[2257] <210>49

[2258] <211>915

[2259] <212>DNA

[2260] <213>人

[2261] <400>49

[2262] atggatcccc tgggcccggc caagccacag tggtcgtggc gctgctgtct gaccacgctg 60[2263] ctgtttcagc tgctgatggc tgtgtgtttc ttctcctatc tgcgtgtgtc tcaagacgat 120[2264] cccactgtgt accctaatgg gtcccgcttc ccagacagca cagggacccc cgcccactcc 180[2265] atccccctga tcctgctgtg gacgtggcct tttaacaaac ccatagctct gccccgctgc 240[2266] tcagagatgg tgcctggcac ggctgactgc aacatcactg ccgaccgcaa ggtgtatcca 300[2267] caggcagacg cggtcatcgt gcaccaccga gaggtcatgt acaaccccag tgcccagctc 360[2268] ccacgctccc cgaggcggca ggggcagcga tggatctggt tcagcatgga gtccccaagc 420[2269] cactgctggc agctgaaagc catggacgga tacttcaatc tcaccatgtc ctaccgcagc 480[2270] gactccgaca tcttcacgcc ctacggctgg ctggagccgt ggtccggcca gcctgcccac 540[2271] ccaccgctca acctctcggc caagaccgag ctggtggcct gggcagtgtc caactggggg 600[2272] ccaaactccg ccagggtgcg ctactaccag agcctgcagg cccatctcaa ggtggacgtg 660[2273] tacggacgct cccacaagcc cctgccccag ggaaccatga tggagacgct gtcccggtac 720[2274] aagttctatc tggccttcga gaactccttg caccccgact acatcaccga gaagctgtgg 780[2275] aggaacgccc tggaggcctg ggccgtgccc gtggtgctgg gccccagcag aaggaacctc 840[2276] attttcctgg ggcctcacct gagtgggggc ctcatctacc taaggactcg tttgcctgaa 900[2277] gcttcacctg cctga 915[2278] <210>50

[2279] <211>1095

[2280] <212>DNA

[2281] <213>人

[2282] <400>50

[2283] atggatcccc tgggcccggc caagccacag tggtcgtggc gctgctgtct gaccacgctg 60[2284] ctgtttcagc tgctgatggc tgtgtgtttc ttctcctatc tgcgtgtgtc tcaagacgat 120[2285] cccactgtgt accctaatgg gtcccgcttc ccagacagca cagggacccc cgcccactcc 180[2286] atccccctga tcctgctgtg gacgtggcct tttaacaaac ccatagctct gccccgctgc 240[2287] tcagagatgg tgcctggcac ggctgactgc aacatcactg ccgaccgcaa ggtgtatcca 300[2288] caggcagacg cggtcatcgt gcaccaccga gaggtcatgt acaaccccag tgcccagctc 360[2289] ccacgctccc cgaggcggca ggggcagcga tggatctggt tcagcatgga gtccccaagc 420[2290] cactgctggc agctgaaagc catggacgga tacttcaatc tcaccatgtc ctaccgcagc 480[2291] gactccgaca tcttcacgcc ctacggctgg ctggagccgt ggtccggcca gcctgcccac 540[2292] ccaccgctca acctctcggc caagaccgag ctggtggcct gggcagtgtc caactggggg 600[2293] ccaaactccg ccagggtgcg ctactaccag agcctgcagg cccatctcaa ggtggacgtg 660[2294] tacggacgct cccacaagcc cctgccccag ggaaccatga tggagacgct gtcccggtac 720[2295] aagttctatc tggccttcga gaactccttg caccccgact acatcaccga gaagctgtgg 780[2296] aggaacgccc tggaggcctg ggccgtgccc gtggtgctgg gccccagcag aagcaactac 840[2297] gagaggttcc tgccacccga cgccttcatc cacgtggacg acttccagag ccccaaggac 900[2298] ctggcccggt acctgcagga gctggacaag gaccacgccc gctacctgag ctactttcgc 960[2299] tggcgggaga cgctgcggcc tcgctccttc agctgggcac tcgctttctg caaggcctgc 1020[2300] tggaaactgc aggaggaatc cagtgggggc ctcatctacc taaggactcg tttgcctgaa 1080[2301] gcttcacctg cctga 1095[2302] <210>51

[2303] <211>1182

[2304] <212>DNA

[2305] <213>人

[2306] <400>51

[2307] gtcctgagca gccaacacac cagcccagac agctgcaagt caccatggac gctgaaggcc 60[2308] tggcgctgct gctgccgccc gtcaccctgg cagccctggt ggacagctgg ctccgagagg 120[2309] actgcccagg gctcaactac gcagccttgg tcagcggggc aggcccctcg caggcggcgc 180[2310] tgtgggccaa atcccctggg gtactggcag ggcagccttt cttcgatgcc atatttaccc 240[2311] aactcaactg ccaagtctcc tggttcctcc ccgagggatc gaagctggtg ccggtggcca 300[2312] gagtggccga ggtccggggc cctgcccact gcctgctgct gggggaacgg gtggccctca 360[2313] acacgctggc ccgctgcagt ggcattgcca gtgctgccgc cgctgcagtg gaggccgcca 420[2314] ggggggccgg ctggactggg cacgtggcag gcacgaggaa gaccacgcca ggcttccggc 480[2315] tggtggagaa gtatgggctc ctggtgggcg gggccgcctc gcaccgctac gacctgggag 540[2316] ggctggtgat gttgaaggat aaccatgtgg tgccccccgg tggcgtggag aaggcggtgc 600[2317] gggcggccag acaggcggct gacttcgctc tgaaggtgga agtggaatgc agcagcctgc 660[2318] aggaggtcgt ccaggcagct gaggctggcg ccgaccttgt cctgctggac aacttcaagc 720[2319] cagaggagct gcaccccacg gccaccgcgc tgaaggccca gttcccgagt gtggctgtgg 780[2320] aagccagtgg gggcatcacc ctggacaacc tcccccagtt ctgcgggccg cacatagacg 840[2321] tcatctccat ggggatgctg acccaggcgg tcccagccct tgatttctcc ctcaagctgt 900[2322] ttgccaaaga ggtggctcca gtgcccaaaa tccactagtc ctaaaccgga agaggatgac 960[2323] accggccatg ggttaacgtg gctcctcagg accctctggg tcacacatct ttagggtcag 1020[2324] tgaacaatgg ggcacatttg gcactagctt gagcccaact ctggctctgc cacctgctgc 1080[2325] tcctgtgacc tgtcagggct gacttcacct ctgctcatct cagtttccta atctgtaaaa 1140[2326] tgggtctaat aaaggatcaa ccaaaaaaaa aaaaaaaaaa aa 1182[2327] <210>52

[2328] <211>3600

[2329] <212>DNA

[2330] <213>人

[2331] <400>52

[2332] gaatcaacag aatttgtctt tttgtgactg gtttatttca cttaacttca tcctcaaggt 60[2333] tcaacttaaa ggtgtatcca tgttgtagca cgtgtcagca ttttctttcg ttctcaggct 120[2334] aaatagtatt tcattgtgtg tgtacaccat gtttcatgca ttcattcatc ccttgaaaga 180[2335] ttggtgggtt gtttcctcct ttttgctttt gtgaacagtg ctacgaacat ggttgtacaa 240[2336] acatctcttg gagccccact agcagttcct ttgggtatat accccaaagt ggaattgctg 300[2337] gatctggtag ctcccttttt aattttttga ggaatcgcca cacagtttcc ataacagctg 360[2338] caccatttta cattcccaag accttttttt tttttttttt tttaagaaga aaagatgtgt 420[2339] ttctgcattt ctggaagtct atgctgcatt tccatttgtt gaaatttaag accagagtca 480[2340] tcttttctgc tgtaattata atggtcactg gcttgtgcct tttcctcctc tctctgcccc 540[2341] atctgcacgg ggtctttgaa caagtcccag caccttggtg gacaagcctg tgtccctggc 600[2342] ccatcatgga agccgctgcc tttcagagtg ggagtctgta ccctgttgcc tcattccttg 660[2343] ctgcgcccat gagtgagctt gtgcctgacc tctccttcca ggtggactta cacactgggc 720[2344] tgtcggagtt ctcggtgacg cagcgccggc tggcccatgg ctggaatgag tttgttgctg 780[2345] acaacagcga acctgtgtgg aagaaatacc tggatcagtt taagaacccc ctgatcctgc 840[2346] tgctgctggg ctctgccctg gtgagtgtcc tcaccaagga gtatgaggac gccgtcagca 900[2347] tcgccacggc agtgcttgtc gtggtcactg tcgccttcat ccaggagtac aggtcggaga 960[2348] aatctctgga agagctgacc aagctggttc ctccagaatg taactgccta agagaaggaa 1020[2349] aactccagca cctgcttgct cgagaactgg ttcctggtga tgtcgtatct ctctcgatcg 1080[2350] gagaccggat ccctgcagac atccgactca ctgaggtcac ggacctcttg gtggatgaat 1140[2351] ccagtttcac cggggaagcc gagccatgta gtaaaacaga cagccccttg acaggcggtg 1200[2352] gggacctcac caccctcagc aacatcgtct tcatggggac cctggtgcag tatgggaggg 1260[2353] gccagggggt cgtgattgga acaggggaaa gctctcagtt cggagaagtg tttaagatga 1320[2354] tgcaggctga agagacacct aaaactcctt tgcagaaaag catggacagg ctaggaaagc 1380[2355] aactgacact cttctccttt ggcataatcg gtctcatcat gctcattggc tggtcgcaag 1440[2356] ggaaacaact cctgagtatg ttcacgatcg gggtcagcct ggctgtggcg gctattccag 1500[2357] agggtctgcc catcgtcgtc atggtgacgc tggtcctggg agtgctgcgg atggccaaga 1560[2358] agcgggtcat cgtgaagaag ttacccatcg tggagacttt aggttgctgc agcgttctct 1620[2359] gttctgacaa gacggggact ctgactgcca atgaaatgac agtgacccag cttgtaacgt 1680[2360] cagatgggct tcgtgccgag gtcagcggag ttgggtatga cggtcaaggg actgtgtgtc 1740[2361] ttctaccatc caaggaagtc attaaggaat tttccaatgt ctcagtggga aagttagtgg 1800[2362] aggcgggctg tgttgccaac aatgcggtca tcagaaagaa cgccgtgatg gggcagccca 1860[2363] ccgagggtgc attgatggcc ctggcgatga agatggactt aagtgatatt aaaaattcat 1920[2364] atataagaaa aaaagagatt ccattcagtt cagagcagaa gtggatggcg gtgaaatgca 1980[2365] gtctgaagac tgaggatcag gaagacattt acttcatgaa aggggccttg gaagaggtga 2040[2366] tccgctactg caccatgtac aacaacgggg gcatccccct gccgctgacg ccccagcaga 2100[2367] ggtcattctg cctgcaggaa gagaagagga tggggtcgct cggtttgcgg gtgctggccc 2160[2368] tggcttctgg gcccgagctg gggcggctga cgtttctagg tcttgtgggc atcattgacc 2220[2369] ccccgagagt tggcgtgaag gaagcagtcc aggttctctc cgagtctggt gtgtctgtga 2280[2370] agatgataac gggggatgcc ctggagacgg ccttggccat aggaagaaac atcggcctgt 2340[2371] gcaacgggaa gctgcaagcc atgtccgggg aggaggtgga cagcgtggag aagggcgagc 2400[2372] tggccgaccg cgtggggaag gtgtccgtgt tcttcaggac cagcccaaag cacaagctca 2460[2373] aaatcatcaa ggctctgcag gagtcagggg cgatcgtggc catgactggg gatggggtga 2520[2374] acgacgcagt ggccctgaag tctgcagaca ttgggatcgc catggggcag acagggacgg 2580[2375] acgtcagcaa agaggccgcc aacatgatcc tggtggatga tgacttctca gccatcatga 2640[2376] atgcagtgga ggaaggcaag ggtatttttt acaacatcaa aaactttgtc cgattccagc 2700[2377] tgagcacgag catctccgcc ctgagtctca tcactctgtc caccgtgttc aacctgccca 2760[2378] gccccctcaa cgccatgcag atcctatgga tcaacatcat catggatggg ccaccggcgc 2820[2379] agagcttggg ggtagagccc gttgacaaag acgccttcag gcagccacca cggagtgtgc 2880[2380] gggacaccat cctcagcaga gccctcatcc tgaagatcct catgtccgcg gccatcatca 2940[2381] tcagcgggac cctctttatc ttctggaagg agatgcctga agacagagca agcactcccc 3000[2382] gcaccacgac gatgacgttc acttgttttg tgtttttcga tctcttcaac gccttgacct 3060[2383] gccgctctca gaccaagctg atatttgaga tcggctttct caggaaccac atgttcctct 3120[2384] actccgtcct ggggtccatc ctggggcagc tggcggtcat ttacatcccc ccgctgcaga 3180[2385] gggtcttcca gacggagaac ctgggagcgc ttgatttgct gtttttaact ggattggcct 3240[2386] catccgtctt cattttgtca gagctcctca aactatgtga aaaatactgt tgcagcccca 3300[2387] agagagtcca gatgcaccct gaagatgtgt agtggaccgc actccgcggc accttcccta 3360[2388] atcatctcga tctggttgtg actgtggccc ctgccgtgtc tcctcgtcag gggagacttt 3420[2389] taggaggccg cagccttcca tcaccggatc agtttttcct cttaggaaag ctgcaggaac 3480[2390] ctcgtgggct ccagggaccc aggcccacat ccatccagcg ttcccgctgg ctgtgggaca 3540[2391] gacagggagg ggcctgtaca gaaacaccac actgtttatt aaatcacaat gatttttatt 3600[2392] <210>53

[2393] <211>4192

[2394] <212>DNA

[2395] <213>人

[2396] <400>53

[2397] tccaagctca aagaagcaga ggccgctgtt cgtttccttt aggtctttcc actaaagtcg 60[2398] gagtatcttc ttccaagatt tcacgtcttg gtggccgttc caaggagcgc gaggtcggga 120[2399] tggatcttga aggggaccgc aatggaggag caaagaagaa gaactttttt aaactgaaca 180[2400] ataaaagtga aaaagataag aaggaaaaga aaccaactgt cagtgtattt tcaatgtttc 240[2401] gctattcaaa ttggcttgac aagttgtata tggtggtggg aactttggct gccatcatcc 300[2402] atggggctgg acttcctctc atgatgctgg tgtttggaga aatgacagat atctttgcaa 360[2403] atgcaggaaa tttagaagat ctgatgtcaa acatcactaa tagaagtgat atcaatgata 420[2404] cagggttctt catgaatctg gaggaagaca tgaccaggta tgcctattat tacagtggaa 480[2405] ttggtgctgg ggtgctggtt gctgcttaca ttcaggtttc attttggtgc ctggcagctg 540[2406] gaagacaaat acacaaaatt agaaaacagt tttttcatgc tataatgcga caggagatag 600[2407] gctggtttga tgtgcacgat gttggggagc ttaacacccg acttacagat gatgtctcca 660[2408] agattaatga aggaattggt gacaaaattg gaatgttctt tcagtcaatg gcaacatttt 720[2409] tcactgggtt tatagtagga tttacacgtg gttggaagct aacccttgtg attttggcca 780[2410] tcagtcctgt tcttggactg tcagctgctg tctgggcaaa gatactatct tcatttactg 840[2411] ataaagaact cttagcgtat gcaaaagctg gagcagtagc tgaagaggtc ttggcagcaa 900[2412] ttagaactgt gattgcattt ggaggacaaa agaaagaact tgaaaggtac aacaaaaatt 960[2413] tagaagaagc taaaagaatt gggataaaga aagctattac agccaatatt tctataggtg 1020[2414] ctgctttcct gctgatctat gcatcttatg ctctggcctt ctggtatggg accaccttgg 1080[2415] tcctctcagg ggaatattct attggacaag tactcactgt attttctgta ttaattgggg 1140[2416] cttttagtgt tggacaggca tctccaagca ttgaagcatt tgcaaatgca agaggagcag 1200[2417] cttatgaaat cttcaagata attgataata agccaagtat tgacagctat tcgaagagtg 1260[2418] ggcacaaacc agataatatt aagggaaatt tggaattcag aaatgttcac ttcagttacc 1320[2419] catctcgaaa agaagttaag atcttgaagg gtctgaacct gaaggtgcag agtgggcaga 1380[2420] cggtggccct ggttggaaac agtggctgtg ggaagagcac aacagtccag ctgatgcaga 1440[2421] ggctctatga ccccacagag gggatggtca gtgttgatgg acaggatatt aggaccataa 1500[2422] atgtaaggtt tctacgggaa atcattggtg tggtgagtca ggaacctgta ttgtttgcca 1560[2423] ccacgatagc tgaaaacatt cgctatggcc gtgaaaatgt caccatggat gagattgaga 1620[2424] aagctgtcaa ggaagccaat gcctatgact ttatcatgaa actgcctcat aaatttgaca 1680[2425] ccctggttgg agagagaggg gcccagttga gtggtgggca gaagcagagg atcgccattg 1740[2426] cacgtgccct ggttcgcaac cccaagatcc tcctgctgga tgaggccacg tcagccttgg 1800[2427] acacagaaag cgaagcagtg gttcaggtgg ctctggataa ggccagaaaa ggtcggacca 1860[2428] ccattgtgat agctcatcgt ttgtctacag ttcgtaatgc tgacgtcatc gctggtttcg 1920[2429] atgatggagt cattgtggag aaaggaaatc atgatgaact catgaaagag aaaggcattt 1980[2430] acttcaaact tgtcacaatg cagacagcag gaaatgaagt tgaattagaa aatgcagctg 2040[2431] atgaatccaa aagtgaaatt gatgccttgg aaatgtcttc aaatgattca agatccagtc 2100[2432] taataagaaa aagatcaact cgtaggagtg tccgtggatc acaagcccaa gacagaaagc 2160[2433] ttagtaccaa agaggctctg gatgaaagta tacctccagt ttccttttgg aggattatga 2220[2434] agctaaattt aactgaatgg ccttattttg ttgttggtgt attttgtgcc attataaatg 2280[2435] gaggcctgca accagcattt gcaataatat tttcaaagat tataggggtt tttacaagaa 2340[2436] ttgatgatcc tgaaacaaaa cgacagaata gtaacttgtt ttcactattg tttctagccc 2400[2437] ttggaattat ttcttttatt acatttttcc ttcagggttt cacatttggc aaagctggag 2460[2438] agatcctcac caagcggctc cgatacatgg ttttccgatc catgctcaga caggatgtga 2520[2439] gttggtttga tgaccctaaa aacaccactg gagcattgac taccaggctc gccaatgatg 2580[2440] ctgctcaagt taaaggggct ataggttcca ggcttgctgt aattacccag aatatagcaa 2640[2441] atcttgggac aggaataatt atatccttca tctatggttg gcaactaaca ctgttactct 2700[2442] tagcaattgt acccatcatt gcaatagcag gagttgttga aatgaaaatg ttgtctggac 2760[2443] aagcactgaa agataagaaa gaactagaag gtgctgggaa gatcgctact gaagcaatag 2820[2444] aaaacttccg aaccgttgtt tctttgactc aggagcagaa gtttgaacat atgtatgctc 2880[2445] agagtttgca ggtaccatac agaaactctt tgaggaaagc acacatcttt ggaattacat 2940[2446] tttccttcac ccaggcaatg atgtattttt cctatgctgg atgtttccgg tttggagcct 3000[2447] acttggtggc acataaactc atgagctttg aggatgttct gttagtattt tcagctgttg 3060[2448] tctttggtgc catggccgtg gggcaagtca gttcatttgc tcctgactat gccaaagcca 3120[2449] aaatatcagc agcccacatc atcatgatca ttgaaaaaac ccctttgatt gacagctaca 3180[2450] gcacggaagg cctaatgccg aacacattgg aaggaaatgt cacatttggt gaagttgtat 3240[2451] tcaactatcc cacccgaccg gacatcccag tgcttcaggg actgagcctg gaggtgaaga 3300[2452] agggccagac gctggctctg gtgggcagca gtggctgtgg gaagagcaca gtggtccagc 3360[2453] tcctggagcg gttctacgac cccttggcag ggaaagtgct gcttgatggc aaagaaataa 3420[2454] agcgactgaa tgttcagtgg ctccgagcac acctgggcat cgtgtcccag gagcccatcc 3480[2455] tgtttgactg cagcattgct gagaacattg cctatggaga caacagccgg gtggtgtcac 3540[2456] aggaagagat tgtgagggca gcaaaggagg ccaacataca tgccttcatc gagtcactgc 3600[2457] ctaataaata tagcactaaa gtaggagaca aaggaactca gctctctggt ggccagaaac 3660[2458] aacgcattgc catagctcgt gcccttgtta gacagcctca tattttgctt ttggatgaag 3720[2459] ccacgtcagc tctggataca gaaagtgaaa aggttgtcca agaagccctg gacaaagcca 3780[2460] gagaaggccg cacctgcatt gtgattgctc accgcctgtc caccatccag aatgcagact 3840[2461] taatagtggt gtttcagaat ggcagagtca aggagcatgg cacgcatcag cagctgctgg 3900[2462] cacagaaagg catctatttt tcaatggtca gtgtccaggc tggaacaaag cgccagtgaa 3960[2463] ctctgactgt atgagatgtt aaatactttt taatatttgt ttagatatga catttattca 4020[2464] aagttaaaag caaacactta cagaattatg aagaggtatc tgtttaacat ttcctcagtc 4080[2465] aagttcagag tcttcagaga cttcgtaatt aaaggaacag agtgagagac atcatcaagt 4140[2466] ggagagaaat catagtttaa actgcattat aaattttata acagaattaa ag 4192[2467] <210>54

[2468] <211>771

[2469] <212>DNA

[2470] <213>人

[2471] <400>54

[2472] gctgtctcta cacacgtggc cctcggggcc tacgccccgc tcacaaagca tgggacactg 60[2473] gtggtggagg atgtggtggc atcctgcttc gcggccgtgg ctgaccacca cctggctcag 120[2474] ttggccttct ggcccctgag actctttcac agcttggcat ggggcagctg gaccccgggg 180[2475] gagggtgtgc attggtaccc ccagctgctc taccgcctgg ggcgtctcct gctagaagag 240[2476] ggcagcttcc acccactggg catgtccggg gcagggagct gaaaggactc caccgctgcc 300[2477] ctcctggaac tgctgtactg ggtccagaag cctctcagcc aggagggagc tggccctgga 360[2478] agggacctga gctgggggac actggctcct gccatctcct ctgccatgaa gatacaccat 420[2479] tgagacttga ctgggcaaca ccagcgtccc ccacccgcgc gtggtgtagt catagagctg 480[2480] caagctgagc tggcgagggg atggttgttg acccctctct cctagagacc ttgaggctgg 540[2481] cacgggactc ccaactcagc ctgctctcac tacgagtttt catactctgc ctcccccatt 600[2482] ggggagggcc cattccatcc atctttaggc ccctttgggt gggcttgcgc ctcagtttga 660[2483] tgctgctaaa ttcccctggg agccagcatg gatctggtgg accgatgctg tcagaactgg 720[2484] gaaggcacca gggtggggca gcatcccggg cattctgagg tatgacattc c 771[2485] <210>55

[2486] <211>4446

[2487] <212>DNA

[2488] <213>人

[2489] <400>55

[2490] ttcttaaccc tttccagctt tcccaccctc tttggcttta gccatggcct tctgatctgt 60[2491] gtttctcagg ggacctgcag gccccagata tagccccatg ctgtcctcct accccagagc 120[2492] acactgttca ggctacttcc actggtactg aaatccagta tttcacttac tcttttcctt 180[2493] tccaatatcc tcatgacatt caatatttca cttactctag gtcctccctg cctaaggccc 240[2494] aagtcaactt tctgtccagt gggatttgta atccaatgcc tcctagccct agcagaatcc 300[2495] catgtggata atcagaaatg tgactggaaa aaggacagag ctctatggct gtgggtccca 360[2496] gtccccactg ctggcagtaa gtccccagca gtgagctgtg taagcacctt acattctgcg 420[2497] cttggttgaa aacagcaagg caagcatcca cttgagaaat gtcaacccct aggaaatccc 480[2498] agcctcaagt ctttctcatc ccttgggaag tgcaaattgg atagagaaga aaccaattaa 540[2499] aaacaaaaca aacaaatcat acttagatat tctggctttt ctcaccaggg ctggattaaa 600[2500] gcatgtactt caaaataata acaacttaag tcaataaata aatgtaagga agtccaaatg 660[2501] ttcacctgaa gacaactgtg gtcatttttt ggcaatccca ggttctcttt tctacctgtt 720[2502] tgctcaatcg tggtctccct ctccctctct tgttggggcc catgcccctg ctttactgtt 780[2503] gccagaggct tgtacttgtt tgccttttag gtaggagcag ttacttccac tcccctcacc 840[2504] tgccataaag catctttata aacaaagcaa gtagaagaaa cacatcctgg tatccaccac 900[2505] attcggcttt tgttgattct gttcacttgg gagcacctgc tgctagggaa taagaaggtt 960[2506] gaggctgaag agtgaggact cttcagctcc cctctggcag gacccgggag aggaaagagc 1020[2507] cctcagctgg tccatcctcc ccactcctgg tcagccttct gttctgagat caaagtggtg 1080[2508] gggtcacatt ctcgagaact gtgctcagcc ccctcatctc acaccctttc cctctccctg 1140[2509] tgtgcctgcc cccctcttac ataaccatgc tggtgattgg caccgtcata aatcaatact 1200[2510] ttgctcactt tcacatcaag taacactatc cagggaggtg gtttcaacaa aggaggaagt 1260[2511] ataaggagat ctaggttcaa attaatgttg cccctagtgg taaaggacag agaccctcag 1320[2512] actgatgaaa tgcactcaga attacttaga caaagcggat atttgccact ctcttcccct 1380[2513] tttcctgtgt ttttgtagtg aagagacctg aaagaaaaaa gtagggagaa cataatgaga 1440[2514] acaaatacgg taatctcttc atttgctagt tcaagtgctg gacttgggac ttaggagggg 1500[2515] caatggagcc gcttagtgcc tacatctgac ttggactgaa atataggtga gagacaagat 1560[2516] tgtctcatat ccggggaaat cataacctat gactaggacg ggaagaggaa gcactgcctt 1620[2517] tacttcagtg ggaatctcgg cctcagcctg caagccaagt gttcacagtg agaaaagcaa 1680[2518] gagaataagc taatactcct gtcctgaaca aggcagcggc tccttggtaa agctactcct 1740[2519] tgatcgatcc tttgcaccgg attgttcaaa gtggacccca ggggagaagt cggagcaaag 1800[2520] aacttaccac caagcagtcc aagaggccca gaagcaaacc tggaggtgag acccaaagaa 1860[2521] agctggaacc atgctgactt tgtacactgt gaggacacag agtctgttcc tggaaagccc 1920[2522] agtgtcaacg cagatgagga agtcggaggt ccccaaatct gccgtgtatg tggggacaag 1980[2523] gccactggct atcacttcaa tgtcatgaca tgtgaaggat gcaagggctt tttcaggagg 2040[2524] gccatgaaac gcaacgcccg gctgaggtgc cccttccgga agggcgcctg cgagatcacc 2100[2525] cggaagaccc ggcgacagtg ccaggcctgc cgcctgcgca agtgcctgga gagcggcatg 2160[2526] aagaaggaga tgatcatgtc cgacgaggcc gtggaggaga ggcgggcctt gatcaagcgg 2220[2527] aagaaaagtg aacggacagg gactcagcca ctgggagtgc aggggctgac agaggagcag 2280[2528] cggatgatga tcagggagct gatggacgct cagatgaaaa cctttgacac taccttctcc 2340[2529] catttcaaga atttccggct gccaggggtg cttagcagtg gctgcgagtt gccagagtct 2400[2530] ctgcaggccc catcgaggga agaagctgcc aagtggagcc aggtccggaa agatctgtgc 2460[2531] tctttgaagg tctctctgca gctgcggggg gaggatggca gtgtctggaa ctacaaaccc 2520[2532] ccagccgaca gtggcgggaa agagatcttc tccctgctgc cccacatggc tgacatgtca 2580[2533] acctacatgt tcaaaggcat catcagcttt gccaaagtca tctcctactt cagggacttg 2640[2534] cccatcgagg accagatctc cctgctgaag ggggccgctt tcgagctgtg tcaactgaga 2700[2535] ttcaacacag tgttcaacgc ggagactgga acctgggagt gtggccggct gtcctactgc 2760[2536] ttggaagaca ctgcaggtgg cttccagcaa cttctactgg agcccatgct gaaattccac 2820[2537] tacatgctga agaagctgca gctgcatgag gaggagtatg tgctgatgca ggccatctcc 2880[2538] ctcttctccc cagaccgccc aggtgtgctg cagcaccgcg tggtggacca gctgcaggag 2940[2539] caattcgcca ttactctgaa gtcctacatt gaatgcaatc ggccccagcc tgctcatagg 3000[2540] ttcttgttcc tgaagatcat ggctatgctc accgagctcc gcagcatcaa tgctcagcac 3060[2541] acccagcggc tgctgcgcat ccaggacata cacccctttg ctacgcccct catgcaggag 3120[2542] ttgttcggca tcacaggtag ctgagcggct gcccttgggt gacacctccg agaggcagcc 3180[2543] agacccagag ccctctgagc cgccactccc gggccaagac agatggacac tgccaagagc 3240[2544] cgacaatgcc ctgctggcct gtctccctag ggaattcctg ctatgacagc tggctagcat 3300[2545] tcctcaggaa ggacatgggt gccccccacc cccagttcag tctgtaggga gtgaagccac 3360[2546] agactcttac gtggagagtg cactgacctg taggtcagga ccatcagaga ggcaaggttg 3420[2547] ccctttcctt ttaaaaggcc ctgtggtctg gggagaaatc cctcagatcc cactaaagtg 3480[2548] tcaaggtgtg gaagggacca agcgaccaag gataggccat ctggggtcta tgcccacata 3540[2549] cccacgtttg ttcgcttcct gagtcttttc attgctacct ctaatagtcc tgtctcccac 3600[2550] ttcccactcg ttcccctcct cttccgagct gctttgtggg ctccaggcct gtactcatcg 3660[2551] gcaggtgcat gagtatctgt gggagtcctc tagagagatg agaagccagg aggcctgcac 3720[2552] caaatgtcag aagcttggca tgacctcatt ccggccacat cattctgtgt ctctgcatcc 3780[2553] atttgaacac attattaagc accgataata ggtagcctgc tgtggggtat acagcattga 3840[2554] ctcagatata gatcctgagc tcacagagtt tatagttaaa aaaacaaaca gaaacacaaa 3900[2555] caatttggat caaaaggaga aatgataagt gacaaaagca gcacaaggaa tttccctgtg 3960[2556] tggatgctga gctgtgatgg cgggcactgg gtacccaagt gaaggttccc gaggacatga 4020[2557] gtctgtagga gcaagggcac aaactgcagc tgtgagtgcg tgtgtgtgat ttggtgtagg 4080[2558] taggtctgtt tgccacttga tggggcctgg gtttgttcct ggggctggaa tgctgggtat 4140[2559] gctctgtgac aaggctacgc tgacaatcag ttaaacacac cggagaagaa ccatttacat 4200[2560] gcaccttata tttctgtgta cacatctatt ctcaaagcta aagggtatga aagtgcctgc 4260[2561] cttgtttata gccacttgtg agtaaaaatt tttttgcatt ttcacaaatt atactttata 4320[2562] taaggcattc cacacctaag aactagtttt gggaaatgta gccctgggtt taatgtcaaa 4380[2563] tcaaggcaaa aggaattaaa taatgtactt ttggctaaaa aaaaaaaaaa aaaaaaaaaa 4440[2564] aaaaaa 4446[2565] <210>56

[2566] <211>1276

[2567] <212>DNA

[2568] <213>人

[2569] <400>56

[2570] tgagatcact tcccttgcac agtttggaag ggagagcact ttattacaga ccttggaagc 60[2571] aagaggattg cattcagcct agttcctggt tgctggccaa agggatcatg gacattgaag 120[2572] catattttga aagaattggc tataagaact ctaggaacaa attggacttg gaaacattaa 180[2573] ctgacattct tgagcaccag atccgggctg ttccctttga gaaccttaac atgcattgtg 240[2574] ggcaagccat ggagttgggc ttagaggcta tttttgatca cattgtaaga agaaaccggg 300[2575] gtgggtggtg tctccaggtc aatcaacttc tgtactgggc tctgaccaca atcggttttc 360[2576] agaccacaat gttaggaggg tatttttaca tccctccagt taacaaatac agcactggca 420[2577] tggttcacct tctcctgcag gtgaccattg acggcaggaa ttacattgtc gatgctgggt 480[2578] ctggaagctc ctcccagatg tggcagcctc tagaattaat ttctgggaag gatcagcctc 540[2579] aggtgccttg cattttctgc ttgacagaag agagaggaat ctggtacctg gaccaaatca 600[2580] ggagagagca gtatattaca aacaaagaat ttcttaattc tcatctcctg ccaaagaaga 660[2581] aacaccaaaa aatatactta tttacgcttg aacctcgaac aattgaagat tttgagtcta 720[2582] tgaatacata cctgcagacg tctccaacat cttcatttat aaccacatca ttttgttcct 780[2583] tgcagacccc agaaggggtt tactgtttgg tgggcttcat cctcacctat agaaaattca 840[2584] attataaaga caatacagat ctggtcgagt ttaaaactct cactgaggaa gaggttgaag 900[2585] aagtgctgaa aaatatattt aagatttcct tggggagaaa tctcgtgccc aaacctggtg 960[2586] atggatccct tactatttag aataaggaac aaaataaacc cttgtgtatg tatcacccaa 1020[2587] ctcactaatt atcaacttat gtgctatcag atatcctctc taccctcacg ttattttgaa 1080[2588] gaaaatccta aacatcaaat actttcatcc ataaaaatgt cagcatttat taaaaaacaa 1140[2589] taacttttta aagaaacata aggacacatt ttcaaattaa taaaaataaa ggcattttaa 1200[2590] ggatggcctg tgattatctt gggaagcaga gtgattcatg ctagaaaaca tttaatattg 1260[2591] atttattgtt gaattc 1276[2592] <210>57

[2593] <211>4999

[2594] <212>DNA

[2595] <213>人

[2596] <400>57

[2597] gaggaggatt cgcagttcaa catcaaggtc cctgtgcgtt ttattgcgac ctgccggtgg 60[2598] gaactttgtc tccgagtcgg agcagcatgg agcggcggag cgagagcccg tgtctgcggg 120[2599] acagccccga ccggcggagc ggcagcccgg acgtcaaggg gcctccccca gtgaaggtgg 180[2600] cccggctgga gcagaacggc agccccatgg gagcccgcgg gaggcccaac ggcgccgtgg 240[2601] ccaaggccgt gggaggtttg atgattcctg tcttttgtgt cgtggagcag ttggacggct 300[2602] ctcttgaata tgacaacaga gaagaacacg ccgagtttgt cctggtgcgg aaagatgtgc 360[2603] tttttagcca gctggtggag actgcgctcc tggccctggg gtattctcac agctctgcgg 420[2604] cccaggccca aggaataatc aagctgggaa ggtggaaccc tctccccctc agttatgtga 480[2605] cagatgcacc cgacgcgaca gtggccgaca tgctacaaga tgtctatcat gttgtgacgt 540[2606] tgaaaatcca attacaaagt tgttcaaagt tggaagactt gcctgcggag cagtggaacc 600[2607] atgccacagt ccgcaatgcc ttaaaggaac tgctcaaaga gatgaaccag agcacattag 660[2608] ccaaagaatg ccctctctcc cagagtatga tttcatccat tgtaaatagc acatattatg 720[2609] ccaatgtgtc agcaaccaag tgccaggagt ttgggagatg gtataaaaag tacaagaaga 780[2610] ttaaagtgga aagagtggaa cgagaaaacc tttcagacta ttgtgttctg ggccagcgtc 840[2611] caatgcattt accaaatatg aaccagctgg catccctggg gaaaaccaac gaacagtctc 900[2612] ctcacagcca aattcaccac agtactccaa tccgaaacca agtgcccgca ttacagccca 960[2613] tcatgagccc tggtcttctt tctccccagc ttagtccaca acttgtaagg caacaaatag 1020[2614] ccatggccca tctgataaac caacagattg ccgttagccg gctcctggct caccagcatc 1080[2615] ctcaagccat caaccagcag ttcctgaacc atccacccat ccccagagca gttaagccag 1140[2616] agccaaccaa ctcttccgtg gaagtctctc cagatatcta ccagcaagtc agagatgagc 1200[2617] tgaagagggc cagtgtgtcc caagctgtct ttgcaagagt ggcattcaac cgcacacagg 1260[2618] gattgttgtc tgagattctg cgtaaggaag aagaccctcg gacagcctct cagtctcttc 1320[2619] tagtaaacct gagggccatg cagaatttcc tcaatctgcc agaagtggag cgagatcgca 1380[2620] tctaccagga tgagagggag cggagcatga atcccaatgt gagcatggtc tcctcggcct 1440[2621] ccagcagtcc cagctcctcc cgaacccctc aggccaaaac ctcgacaccg acaacagacc 1500[2622] tccctattaa ggtggacggc gccaacatca acatcacagc tgccatttat gacgagatcc 1560[2623] aacaggagat gaaaagggcc aaggtgtctc aagccctgtt tgccaaagtg gctgcaaata 1620[2624] aaagtcaggg ctggctgtgt gaactgctcc gctggaagga gaacccaagc ccagaaaacc 1680[2625] gcaccctctg ggaaaacctc tgtaccatcc gtcgcttcct gaaccttccc cagcatgaga 1740[2626] gggatgtcat ctatgaggag gagtcaaggc atcaccacag cgaacgcatg caacacgtgg 1800[2627] tccagcttcc ccctgagccg gtgcaggtac ttcatagaca gcagtctcag ccagccaagg 1860[2628] agagttcccc tcccagagaa gaagcgcctc ccccacctcc tccgactgaa gacagttgtg 1920[2629] ccaaaaagcc ccggtctcgc acaaagatct ccttagaagc cctggggatc ctccaaagct 1980[2630] ttattcatga tgtaggcctg tacccagacc aggaagccat ccacactctt tcggctcagc 2040[2631] tggatctccc caaacacacc atcatcaagt tcttccagaa ccagcggtac cacgtgaagc 2100[2632] accacgggaa gctgaaagag cacctgggct ccgcggtgga cgtggctgaa tataaggacg 2160[2633] aggagctgct gaccgagtca gaggagaacg acagcgagga aggctccgag gagatgtaca 2220[2634] aagtggaggc tgaggaggaa aatgctgaca aaagcaaggc agcacctgcc gaaattgacc 2280[2635] agagataatg tgaacttcta ctaggcaaag caatacatcg gtccaaggat tttctgcttt 2340[2636] catttcttta aaagtttttt gttagtttgt tttttgtttt tgtttttggg tttttttggc 2400[2637] tttatttttg tctttttatg tctgttttgt ttttcttacc cttttggaca tttctttgtt 2460[2638] gcacaggata cacctataga ctgaataagt tcagtatttc cgaatcagac atcgccttgg 2520[2639] caaagacact aaagcgttac actttatccc gtctctatga ctggatcata gtcattataa 2580[2640] tcacaggaga ctctgccttc attatccttg cacttaacgg aagttacatc aggcaagttc 2640[2641] caggatgaaa agaactatga aataaatgaa ggaagctaca agtgtgtgtg tatatgtata 2700[2642] tgtatatatc tctatattta catatatata ttaaaattgc atgggacaga gactttgcaa 2760[2643] tccgaaagaa tagactgtga aatgagttct taaagaaaag acttgtttat gtattaaaaa 2820[2644] aaccacttca cagtgagtcg ctttggcttt ttgataaact gcggcctgct ctcagggtgg 2880[2645] ggtgactatt tttgaattcc tatttatttt ttgtgtttgt ccctgatttt tttttttaat 2940[2646] tctatggctt cctatctggc agcttaatgg gtaatttttg aggtatgtat ttaacaaaat 3000[2647] aaacgacact gccgaaaaaa aaaaaagtga agtgaaaaca atcagggcac attaaaatga 3060[2648] tacaagtcaa ataaatctta aagacacaat gcacacttaa aatgactcaa taaaatgact 3120[2649] tgctacgttc cgttattcaa tttgtcatta ctgtagtgaa cagatgcatt tctgtggaat 3180[2650] tccaaataag taaaactgaa attcagtgca gagaaaactt tgtccactag tgcaagtctt 3240[2651] gatcaaatga cattttgaca ttggacatat ggaattcata gtatgagcca cattttgttg 3300[2652] tgaaatttat ttacctgctt gtggcttcaa atctgaaaat taataagcct gctcgtttaa 3360[2653] aagttgtttg ttgttgctgt ttttttgtct ttttgttttt tactagaaaa tagttcagtg 3420[2654] taatattaag ttagaaaaga agttgctgcc cagttaaagg ggctccctct caaataaatc 3480[2655] tccatccttc cctctcccaa aagacatttc tgatttctgc ttcactttgg gcttcctctt 3540[2656] cttcgtacac attccatcta cctaatcaaa cattttcagt ccctgatctc tcctgtccct 3600[2657] tttcctggga tgacagccct aacaagaact gtttttgaat cgttgtgcag ctccaggcaa 3660[2658] tagagtatgt gaagcgattt cagtagaatc acttactcat cctaaaagaa aacattatcc 3720[2659] cagttaccta catcgcaatt accttatgta aagcagaact aatgctgact ggatgtttaa 3780[2660] tgggatgagc attaaagctg caatctacta tagtactcca gatctctttc ggcttcctat 3840[2661] gagaaacacc agaagcatta ctttccactt ctacttacag taattgcaag aggagacctc 3900[2662] acattcagga ctggcctagt gaacgtaatc catgctttaa actggccatt aaacagtccc 3960[2663] acatggttgg attttttttt tttttttgag ttgtgctttc acaaaacctt gtcaaagacc 4020[2664] tcatgcaata tcactttgaa agttattttc tgtttactac acaaacattg taatataact 4080[2665] gttaatacta tttatatatt tgaaaggtat aaaaggtagg agttaaaaaa aaaacctcta 4140[2666] tgtgtagata ttaactcaga acttacaata tacagggaga agacatgttg caatacaagc 4200[2667] taattctagc tgctcagtaa cctctggagt ttttaaaggg acattttcct gtactttttc 4260[2668] aaataatgat gtttaaaaat tatcttgaca taagcgtcat atacctttgc aaaaggatgg 4320[2669] ttgtttgcag ttagccctgg ccccatcctt cctatttctg tagtatgctg cagctttaat 4380[2670] cagaaagtcc atggttgctg cttcctgatc tccgagttac tctttccaaa ttgtcttctt 4440[2671] acactgttgc tgaaggtcac tctgtacacg taatggaaac tgattttgcc aagctcttac 4500[2672] aaggtggttc atctatcgat ggcatccgca tttggtatct tttacacttc aaccaaaaat 4560[2673] ttattaggta tttttcaatg ctaagtcttg ccttttattt tttaatttca ctgccaagtt 4620[2674] tgcagtggtt ctaagtgaat ctgtgggcat tttagcctgt ggtcttgcca gatctttgcg 4680[2675] aattacaatg catatatgtc tatttattca atatctgtca tataatatct atttggaaga 4740[2676] agaaactttc tcttgtagtg cctcttgaca aagcacaatt tcccgccttt tttttttttt 4800[2677] ttgtgaaatg aaaaaaacaa attgtgtttt attgcggtat caacaatgtg aataaggatt 4860[2678] aacatattgt aaatgttctt ttttccatgt aaatcaacta tctttgttat cactaagtga 4920[2679] taattaattt ttaacttatg tgcattgtta ggctgttaga attttttggt tgttaaaata 4980[2680] aacgcattca ataaatatg 4999[2681] <210>58

[2682] <211>1117

[2683] <212>DNA

[2684] <213>人

[2685] <400>58

[2686] atctcccact cctgcagctc ttctcacagg accagccact agcgcagcct cgagcgatgg 60[2687] cctatgtccc cgcaccgggc taccagccca cctacaaccc gacgctgcct tactaccagc 120[2688] ccatcccggg cgggctcaac gtgggaatgt ctgtttacat ccaaggagtg gccagcgagc 180[2689] acatgaagcg gttcttcgtg aactttgtgg ttgggcagga tccgggctca gacgtcgcct 240[2690] tccacttcaa tccgcggttt gacggctggg acaaggtggt cttcaacacg ttgcagggcg 300[2691] ggaagtgggg cagcgaggag aggaagagga gcatgccctt caaaaagggt gccgcctttg 360[2692] agctggtctt catagtcctg gctgagcact acaaggtggt ggtaaatgga aatcccttct 420[2693] atgagtacgg gcaccggctt cccctacaga tggtcaccca cctgcaagtg gatggggatc 480[2694] tgcaacttca atcaatcaac ttcatcggag gccagcccct ccggccccag ggacccccga 540[2695] tgatgccacc ttaccctggt cccggacatt gccatcaaca gctgaacagc ctgcccacca 600[2696] tggaaggacc cccaaccttc aacccgcctg tgccatattt cgggaggctg caaggagggc 660[2697] tcacagctcg aagaaccatc atcatcaagg gctatgtgcc tcccacaggc aagagctttg 720[2698] ctatcaactt caaggtgggc tcctcagggg acatagctct gcacattaat ccccgcatgg 780[2699] gcaacggtac cgtggtccgg aacagccttc tgaatggctc gtggggatcc gaggagaaga 840[2700] agatcaccca caacccattt ggtcccggac agttctttga tctgtccatt cgctgtggct 900[2701] tggatcgctt caaggtttac gccaatggcc agcacctctt tgactttgcc catcgcctct 960[2702] cggccttcca gagggtggac acattggaaa tccagggtga tgtcaccttg tcctatgtcc 1020[2703] agatctaatc tattcctggg gccataactc atgggaaaac agaattatcc cctaggactc 1080[2704] ctttctaagc ccctaataaa atgtctgagg gtgtctc 1117[2705] <210>59

[2706] <211>2246

[2707] <212>DNA

[2708] <213>人

[2709] <400>59

[2710] gatccagcta tggagaaagc cgcagatctg caggacacag cctcgttaac tctgaagttt 60[2711] aagtttaacc caaagctggg cattgataat cctgtcctct ccctggccga agaccacgac 120[2712] ccctatgatc cctggagcct ggagcggcct cgcttctgtt tactgagcaa agaggagggc 180[2713] aagagttttg gcttccacct gcagcaggag ctgggcaggg ctgggcatgt ggtgtgcagg 240[2714] gtggacccag gcacctctgc ccagcgccag ggtcttcagg aaggagacag gatcctggcg 300[2715] gtgaacaatg atgttgtgga acacgaagac tatgcggtgg tggtacgccg catccgggcc 360[2716] agcagccctc gggtgttgct gacagtattg gcacggcatg cacatgacgt ggcccgagct 420[2717] cagctgggag aagatgccca cctctgtccc accctaggcc caggggtccg gccccggctg 480[2718] tgccacatag tgaaagatga gggtggtttt ggcttcagtg tcacccatgg caatcagggt 540[2719] cctttctggt tggtgctaag tactggagga gcagctgagc gggcaggggt gccccccggg 600[2720] gcccggctgc tggaagtgaa tgggctttgg cagagtggac agcaggtgac cttgctggtg 660[2721] gcagggccag aggtggaaga acagtgtcgc cagctgggat tgcccctggc tgcacccctg 720[2722] gcagagggct gggcactgcc caccaagccc cgctgcctgc acctggagaa agggccccag 780[2723] ggttttgggt tcctgctccg ggaggaaaag ggccttgacg gtcgccctgg acagttcctg 840[2724] tgggaggtgg acccgggact gccagccaag aaggctggga tgcaggctgg ggaccggctg 900[2725] gtggctgtgg ctggggagag cgtggagggg ctgggccatg aggagacagt gtccaggatc 960[2726] caggggcagg gctcctgtgt ctccctcact gtcgtcgacc ctgaggcgga ccgcttcttc 1020[2727] agcatggttc gcctgtcccc actcctcttc ttggagaaca cagaggctcc cgcctcgccc 1080[2728] cagggcagca gctcagcctc actggttgag acagaggacc cttcacttga agacacaagc 1140[2729] gtgccttctg tccctcttgg ctcccgacag tgcttcctgt accctgggcc tggtggcagc 1200[2730] tatggcttcc gactcagttg tgtggccagt gggcctcgtc tcttcatctc ccaggtgact 1260[2731] ccaggaggct cagctgcccg ggctgggctg caagtgggag acgtgattct ggaagtgaac 1320[2732] gggtatcctg ttgggggaca gaatgacctg gagaggcttc agcagctgcc tgaggctgag 1380[2733] ccacccctct gcctgaagct ggcagccagg tctctgcggg gcttggaagc ctggattccc 1440[2734] cctggggctg cagaggactg ggctctggcc tcggatctac tgtagagcac ccctgcttgg 1500[2735] tacagacata ctcaggggct accgtgtctt cactctccag cctgaggtgg tgaaggcagg 1560[2736] atgctctctc taagccagac cagagggact cagacaccac cgatcacagg ctggcccagg 1620[2737] tgctccctcc cttcctgcag gcccacctgc cagcagaggg tgtggttgga ggcctcagac 1680[2738] aggtccctga aggagtctga ggctccagag gatgtcatat gggagtttta gagagctgtg 1740[2739] tcccaaggat gaaggtgtgg ctgtgggtct ggctaggatt gaagccatct ggaccttttc 1800[2740] tagatatgac tccaggaccc ttgagtgtaa tgcaaaaatt tggagaccag ctatgcctgc 1860[2741] cctctgtggg tgccttagca ttgcgggagg gtggtgcttg gtcaccgttg catttgttat 1920[2742] agaaatggcc attcgccata aatctgactg cctgtgtttg tgttggtggg ggtaaggggc 1980[2743] agtggtgtga agggaccaaa agggcctcag gctcaagggg tgggatgcgg ctcctgcagg 2040[2744] agagaggttg agacctggtc aaatttattt cctatcaatc actgaatctc agggataatg 2100[2745] ggtcaaccca gaactgagat gtctgtatga cagccactcc taaaaataaa caacaacaaa 2160[2746] aacaaaaaaa gaagaaaact aaataaaaat aaaaataaaa ataaaaaaaa aaaaaaaaaa 2220[2747] aaaaaaaaaa aaaaaaaaaa aaaaaa 2246[2748] <210>60

[2749] <211>2418

[2750] <212>DNA

[2751] <213>人

[2752] <400>60

[2753] agtccagctt gggtccctga gagctgtgag aaggagatgc ggctgctgct ggccctgttg 60[2754] ggggtcctgc tgagtgtgcc tgggcctcca gtcttgtccc tggaggcctc tgaggaagtg 120[2755] gagcttgagc cctgcctggc tcccagcctg gagcagcaag agcaggagct gacagtagcc 180[2756] cttgggcagc ctgtgcggct gtgctgtggg cgggctgagc gtggtggcca ctggtacaag 240[2757] gagggcagtc gcctggcacc tgctggccgt gtacggggct ggaggggccg cctagagatt 300[2758] gccagcttcc tacctgagga tgctggccgc tacctctgcc tggcacgagg ctccatgatc 360[2759] gtcctgcaga atctcacctt gattacaggt gactcctcga cctccagcaa cgatgatgag 420[2760] gaccccaagt cccataggga cctctcgaat aggcacagtt acccccagca agcaccctac 480[2761] tggacacacc cccagcgcat ggagaagaaa ctgcatgcag tacctgcggg gaacaccgtc 540[2762] aagttccgct gtccagctgc aggcaacccc acgcccacca tccgctggct taaggatgga 600[2763] caggcctttc atggggggaa ccgcattgga ggcattcggc tgcgccatca gcactggagt 660[2764] ctcgtgatgg agagcgtggt gccctcggac cgcggcacat acacctgcct ggtagagaac 720[2765] gctgtgggca gcatccgtta taactacctg ctagatgtgc tggagcggtc cccgcaccgg 780[2766] cccatcctgc aggccgggct cccggccaac accacagccg tggtgggcag cgacgtggag 840[2767] ctgctgtgca aggtgtacag cgatgcccag ccccacatcc agtggctgaa gcacatcgtc 900[2768] atcaacggca gcagcttcgg agccgacggt ttcccctatg tgcaagtcct aaagactgca 960[2769] gacatcaata gctcagaggt ggaggtcctg tacctgcgga acgtgtcagc cgaggacgca 1020[2770] ggcgagtaca cctgcctcgc aggcaattcc atcggcctct cctaccagtc tgcctggctc 1080[2771] acggtgctgc caggtactgg gcgcatcccc cacctcacat gtgacagcct gactccagca 1140[2772] ggcagaacca agtctcccac tttgcagttc tccctggagt caggctcctc cggcaagtca 1200[2773] agctcatccc tggtacgagg cgtgcgtctc tcctccagcg gccccgcctt gctcgccggc 1260[2774] ctcgtgagtc tagatctacc tctcgaccca ctatgggagt tcccccggga caggctggtg 1320[2775] cttgggaagc ccctaggcga gggctgcttt ggccaggtag tacgtgcaga ggcctttggc 1380[2776] atggaccctg cccggcctga ccaagccagc actgtggccg tcaagatgct caaagacaac 1440[2777] gcctctgaca aggacctggc cgacctggtc tcggagatgg aggtgatgaa gctgatcggc 1500[2778] cgacacaaga acatcatcaa cctgcttggt gtctgcaccc aggaagggcc cctgtacgtg 1560[2779] atcgtggagt gcgccgccaa gggaaacctg cgggagttcc tgcgggcccg gcgcccccca 1620[2780] ggccccgacc tcagccccga cggtcctcgg agcagtgagg ggccgctctc cttcccagtc 1680[2781] ctggtctcct gcgcctacca ggtggcccga ggcatgcagt atctggagtc ccggaagtgt 1740[2782] atccaccggg acctggctgc ccgcaatgtg ctggtgactg aggacaatgt gatgaagatt 1800[2783] gctgactttg ggctggcccg cggcgtccac cacattgact actataagaa aaccagcaac 1860[2784] ggccgcctgc ctgtgaagtg gatggcgccc gaggccttgt ttgaccgggt gtacacacac 1920[2785] cagagtgacg tgtggtcttt tgggatcctg ctatgggaga tcttcaccct cgggggctcc 1980[2786] ccgtatcctg gcatcccggt ggaggagctg ttctcgctgc tgcgggaggg acatcggatg 2040[2787] gaccgacccc cacactgccc cccagagctg tacgggctga tgcgtgagtg ctggcacgca 2100[2788] gcgccctccc agaggcctac cttcaagcag ctggtggagg cgctggacaa ggtcctgctg 2160[2789] gccgtctctg aggagtacct cgacctccgc ctgaccttcg gaccctattc cccctctggt 2220[2790] ggggacgcca gcagcacctg ctcctccagc gattctgtct tcagccacga ccccctgcca 2280[2791] ttgggatcca gctccttccc cttcgggtct ggggtgcaga catgagcaag gctcaaggct 2340[2792] gtgcaggcac ataggctggt ggccttgggc cttggggctc agccacagcc tgacacagtg 2400[2793] ctcgaccttg atagcatg 2418[2794] <210>61

[2795] <211>1944

[2796] <212>DNA

[2797] <213>人

[2798] <400>61

[2799] ccctctcgcg ccccaggccg gtgtaccccc gcactccgcg ccccggccta gaagctctct 60[2800] ctccccgctc cccggcccgg cccccgcccc gccccgcccc agcccgctgg gccgccatgg 120[2801] agcgctggcc ttggccgtcg ggcggcgcct ggctgctcgt ggctgcccgc gcgctgctgc 180[2802] agctgctgcg ctcagacctg cgtctgggcc gcccgctgct ggcggcgctg gcgctgctgg 240[2803] ccgcgctcga ctggctgtgc cagcgcctgc tgcccccgcc ggccgcactc gccgtgctgg 300[2804] ccgccgccgg ctggatcgcg ttgtcccgcc tggcgcgccc gcagcgcctg ccggtggcca 360[2805] ctcgcgcggt gctcatcacc ggctgtgact ctggttttgg caaggagacg gccaagaaac 420[2806] tggactccat gggcttcacg gtgctggcca ccgtattgga gttgaacagc cccggtgcca 480[2807] tcgagctgcg tacctgctgc tcccctcgcc taaggctgct gcagatggac ctgaccaaac 540[2808] caggagacat tagccgcgtg ctagagttca ccaaggccca caccaccagc accggcctgt 600[2809] ggggcctcgt caacaacgca ggccacaatg aagtagttgc tgatgcggag ctgtctccag 660[2810] tggccacttt ccgtagctgc atggaggtga atttctttgg cgcgctcgag ctgaccaagg 720[2811] gcctcctgcc cctgctgcgc agctcaaggg gccgcatcgt gactgtgggg agcccagcgg 780[2812] gggacatgcc atatccgtgc ttgggggcct atggaacctc caaagcggcc gtggcgctac 840[2813] tcatggacac attcagctgt gaactccttc cctggggggt caaggtcagc atcatccagc 900[2814] ctggctgctt caagacagag tcagtgagaa acgtgggtca gtgggaaaag cgcaagcaat 960[2815] tgctgctggc caacctgcct caagagctgc tgcaggccta cggcaaggac tacatcgagc 1020[2816] acttgcatgg gcagttcctg cactcgctac gcctggccat gtccgacctc accccagttg 1080[2817] tagatgccat cacagatgcg ctgctggcag ctcggccccg ccgccgctat taccccggcc 1140[2818] agggcctggg gctcatgtac ttcatccact actacctgcc tgaaggcctg cggcgccgct 1200[2819] tcctgcaggc cttcttcatc agtcactgtc tgcctcgagc actgcagcct ggccagcctg 1260[2820] gcactacccc accacaggac gcagcccagg gcccaaacct gagccccggc ccttccccag 1320[2821] cagtggctcg gtgagccatg tgcacctatg gcccagccac tgcagcacag gaggctccgt 1380[2822] gagcccttgg ttcctccccg aaaaccccca gcattacgat cccccaagtg tcctggaccc 1440[2823] tggcctaaag aatcccaccc ccacttcatg cccactgccg atgcccaatc caggcccggt 1500[2824] gaggccaagg tttcccagtg agcctctgcg cctctccact gtttcatgag cccaaacacc 1560[2825] ctcctggcac aacgctctac cctgcagctt ggagaactcc gctggatggg gagtctcatg 1620[2826] caagacttca ctgcagcctt tcacaggact ctgcagatag tgcctctgca aactaaggag 1680[2827] tgactaggtg ggttggggac cccctcagga ttgtttctcg gcaccagtgc ctcagtgctg 1740[2828] caattgaggg ctaaatccca agtgtctctt gactggctca agaattaggg ccccaactac 1800[2829] acacccccaa gccacaggga agcatgtact gtacttccca attgccacat tttaaataaa 1860[2830] gacaaatttt tatttcttct aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1920[2831] aaaaaaaaaa aaaaaaaaaa aaaa 1944[2832] <210>62

[2833] <211>661

[2834] <212>DNA

[2835] <213>人

[2836] <400>62

[2837] tttttttttt tttaaaatca atacaaatct tttattaaag atctactcat accatggctg 60[2838] aaatcatcta ttattgttgc tagttagcct ctcttctata gttgggtaat gttgtcttgc 120[2839] cactgtgttt gccatctctc ccaagtgaaa agaacacttt ttaaaaaaaa ttaattgctc 180[2840] caagttttca ggcccagggg aggctctccc attctcctcc ttcaataagt cccgtccagg 240[2841] aaagggtgat cttgtggata aattcatcat acttcacttt gccattgggt tcgatatctg 300[2842] cttccctgaa gagatcatcc acttccttgt gggtgagctt ctcccccaga ctcgtgagtt 360[2843] ttgaccgcag gtcggacgcc atgacgtaac ctttcttctc cttgtccacc atcaacatgg 420[2844] ctagaagaat ttctttcttt gggtcttctt gttttatttg catgtgcata atggtcagaa 480[2845] aagtggagaa atccagctct ccatttccgt ctatcccgtg ggtctgcagg tgccgctgca 540[2846] cctcccctgg cgttgggctg gcccccaggc acctcatggc caccatgagg tcgggggctt 600[2847] tatcttcccc ctctgctgct gtcatacaag gagaagcatt tcttgtctca ttaatttggt 660[2848] c 661[2849] <210>63

[2850] <211>532

[2851] <212>DNA

[2852] <213>人

[2853] <220>

[2854] <221>misc_feature

[2855] <222>(519)..(519)

[2856] <223>N EQUALS ANY KIND OF BASE

[2857] <400>63

[2858] taactatgga aaaccatgtt tatttttaat aaaggatgac atttccaatc agtaaaatat 60[2859] cataaaagta taaaaatgta ctaagtacaa tcattagcat tatgttatag gggaatagtg 120[2860] gttataactt ttccctgtaa gatggcacat tggatggtca cagttggctt gatttacaga 180[2861] ggggcaagag taggtgacca gttgtaccag ttgctccagt ttcctaggat ttgggactct 240[2862] tgtaaaatga gaaagtccca ggcaaactgg gacggttggt cctacaagaa aaagagcagc 300[2863] atcagagtgt tggctatagt ttggaactta ggaacaggat cagacattat tttttaactt 360[2864] ctccacctat tttcccttta gctgtgaaat aaaaatccct tttgttatta ctgagggtgt 420[2865] tacagctttc agaggctttt ttaccactgg gtttcatgta attttgactt aatacctatg 480[2866] tcaagcctgg gaagaaaggc agttctaatc aacttgcang tgtggcattc tg 532[2867] <210>64

[2868] <211>1013

[2869] <212>DNA

[2870] <213>人

[2871] <400>64

[2872] atcattccta gaactgaagt tgaaaaggcc atcaggatgt cccggagccg tatcaatgat 60[2873] gctttccgtc tgaatgacaa cagcctagag tttctgggga tacagccaac acttggacct 120[2874] cctaaccagc cccctgtttc catatggctg attgtttttg gagttgtgat gggagtgata 180[2875] gtggttggca ttgtcatcct gatcttcact gggatcagag atcggaagaa gaaaaataaa 240[2876] gcaagaagtg gagaaaatcc ttatgcctcc atcgatatta gcaaaggaga aaataatcca 300[2877] ggattccaaa acactgatga tgttcagacc tccttttaga aaaatctatg tttttcctct 360[2878] tgaggtgatt ttgttgtatg taaatgttaa tttcatggta tagaaaatat aagatgataa 420[2879] agatatcatt aaatgtcaaa actatgactc tgttcagaaa aaaaattgtc caaagacaac 480[2880] atggccaagg agagagcatc ttcattgaca ttgctttcag tatttatttc tgtctctgga 540[2881] tttgacttct gttctgtttc ttaataagga ttttgtatta gagtatatta gggaaagtgt 600[2882] gtatttggtc tcacaggctg ttcagggata atctaaatgt aaatgtctgt tgaatttctg 660[2883] aagttgaaaa caaggatata tcattggagc aagtgttgga tcttgtatgg aatatggatg 720[2884] gatcacttgt agaggacatt gctttttcac ttccaaggtg cttgatcaac atctccctga 780[2885] caacacaaaa ctagagccag gggcctccgt gaactcccag agcatgcctg atagaaactc 840[2886] atttctactg ttctctaact gtggagtgaa tggaaattcc aactgtatgt tcaccctctg 900[2887] aagtgggtac ccagtctctt aaatcttttg tatttgctca cagtgtttga gcagtgctga 960[2888] gcacaaagca gacactcaat aaatgctaga tttacacaaa aaaaaaaaaa aaa 1013[2889] <210>65

[2890] <211>2060

[2891] <212>DNA

[2892] <213>人

[2893] <400>65

[2894] tgttcccagc actcaagcct tgccaccgcc gagccgggct tcctgggtgt ttcaggcaag 60[2895] gaagtctagg tccctggggg gtgaccccca aggaaaaggc agcctccctg cgcacccggt 120[2896] tgcccggagc cctctccagg gccggctggg ctgggggttg ccctggccag caggggcccg 180[2897] ggggcgatgc cacccggtgc cgactgaggc caccgcacca tggcccgctc gctgacctgg 240[2898] cgctgctgcc cctggtgcct gacggaggat gagaaggccg ccgcccgggt ggaccaggag 300[2899] atcaacagga tcctcttgga gcagaagaag caggaccgcg gggagctgaa gctgctgctt 360[2900] ttgggcccag gcgagagcgg gaagagcacc ttcatcaagc agatgcggat catccacggc 420[2901] gccggctact cggaggagga gcgcaagggc ttccggcccc tggtctacca gaacatcttc 480[2902] gtgtccatgc gggccatgat cgaggccatg gagcggctgc agattccatt cagcaggccc 540[2903] gagagcaagc accacgctag cctggtcatg agccaggacc cctataaagt gaccacgttt 600[2904] gagaagcgct acgctgcggc catgcagtgg ctgtggaggg atgccggcat ccgggcctgc 660[2905] tatgagcgtc ggcgggaatt ccacctgctc gattcagccg tgtactacct gtcccacctg 720[2906] gagcgcatca ccgaggaggg ctacgtcccc acagctcagg acgtgctccg cagccgcatg 780[2907] cccaccactg gcatcaacga gtactgcttc tccgtgcaga aaaccaacct gcggatcgtg 840[2908] gacgtcgggg gccagaagtc agagcgtaag aaatggatcc attgtttcga gaacgtgatc 900[2909] gccctcatct acctggcctc actgagtgaa tacgaccagt gcctggagga gaacaaccag 960[2910] gagaaccgca tgaaggagag cctcgcattg tttgggacta tcctggaact accctggttc 1020[2911] aaaagcacat ccgtcatcct ctttctcaac aaaaccgaca tcctggagga gaaaatcccc 1080[2912] acctcccacc tggctaccta tttccccagt ttccagggcc ctaagcagga tgctgaggca 1140[2913] gccaagaggt tcatcctgga catgtacacg aggatgtaca ccgggtgcgt ggacggcccc 1200[2914] gagggcagca agaagggcgc acgatcccga cgccttttca gccactacac atgtgccaca 1260[2915] gacacacaga acatccgcaa ggtcttcaag gacgtgcggg actcggtgct cgcccgctac 1320[2916] ctggacgaga tcaacctgct gtgacccagg ccccacctgg ggcaggcggc accggcgggc 1380[2917] gggtgggagg tgggagtggc tgcagggacc ctagtgtcct ggtctatctc tccagcctcg 1440[2918] gcccacacgc aagggagtcg ggggacggcc cgctgctggc cgctctcttc tctgcctctc 1500[2919] accaggacag ccgcccccca gggtactcct gcccttgctt gactcagttt ccctcctttg 1560[2920] aaagggaagg agcaaaacgg ccatttggga tgccagggtg gatgaaaagg tgaagaaatc 1620[2921] aggggattga gacttgggtg ggtgggcatc tctcaggagc cccatctccg ggcgtgtcac 1680[2922] ctcctgggca gggttctggg accctctgtg ggtgacgcac accctgggat ggggctagta 1740[2923] gagccttcag gcgccttcgg gcgtggactc tggcgcactc tagtggacag gagaaggaac 1800[2924] gccttccagg aacctgtgga ctaggggtgc agggacttcc ctttgcaagg ggtaacagac 1860[2925] cgctggaaaa cactgtcact ttcagagctc ggtggctcac agcgtgtcct gccccggttt 1920[2926] gcggacgaga gaaatcgcgg cccacaagca tcccccatcc cttgcaggct gggggctggg 1980[2927] catgctgcat cttaaccttt tgtatttatt ccctcacctt ctgcagggct ccgtgcgggc 2040[2928] tgaaattaaa gatttcttag 2060[2929] <210>66

[2930] <211>7265

[2931] <212>DNA

[2932] <213>人

[2933] <400>66

[2934] catagagcca gcgggcgcgg gcgggacggg cgccccgcgg ccggacccag ccagggcacc 60[2935] acgctgcccg gccctgcgcc gccaggcact tctttccggg gctcctaggg acgccagaag 120[2936] gaagtcaacc tctgctgctt ctccttggcc tgcgttggac cttccttttt ttgttgtttt 180[2937] tttttgtttt tcccctttct tccttttgaa ttaactggct tcttggctgg atgttttcaa 240[2938] cttctttcct ggctgcgaac ttttccccaa ttgttttcct tttacaacag ggggagaaag 300[2939] tgctctgtgg tccgaggcga gccgtgaagt tgcgtgtgcg tggcagtgtg cgtggcagga 360[2940] tgtgcgtgcg tgtgtaaccc gagccgcccg atctgtttcg atctgcgccg cggagccctc 420[2941] cctcaaggcc cgctccacct gctgcggtta cgcggcgctc gtgggtgttc gtgcctcgga 480[2942] gcagctaacc ggcgggtgct gggcgacggt ggaggagtat cgtctcgctg ctgcccgagt 540[2943] cagggctgag tcacccagct gatgtagaca gtggctgcct tccgaagagt gcgtgtttgc 600[2944] atgtgtgtga ctctgcggct gctcaactcc caacaaacca gaggaccagc cacaaactta 660[2945] accaacatcc ccaaacccga gttcacagat gtgggagagc tgtagaaccc tgagtgtcat 720[2946] cgactgggcc ttcttatgat tgttgtttta agattagctg aagatctctg aaacgctgaa 780[2947] ttttctgcac tgagcgtttt gacagaattc attgagagaa cagagaacat gacaagtact 840[2948] tctagctcag cactgctcca actactgaag ctgattttca aggctactta aaaaaatctg 900[2949] cagcgtacat taatggattt ctgttgtgtt taaattctcc acagattgta ttgtaaatat 960[2950] tttatgaagt agagcatatg tatatattta tatatacgtg cacatacatt agtagcacta 1020[2951] cctttggaag tctcagctct tgcttttcgg gactgaagcc agttttgcat gataaaagtg 1080[2952] gccttgttac gggagataat tgtgttctgt tgggacttta gacaaaactc acctgcaaaa 1140[2953] aactgacagg cattaactac tggaacttcc aaataatgtg tttgctgatc gttttactct 1200[2954] tcgcataaat attttaggaa gtgtatgaga attttgcctt caggaacttt tctaacagcc 1260[2955] aaagacagaa cttaacctct gcaagcaaga ttcgtggaag atagtctcca ctttttaatg 1320[2956] cactaagcaa tcggttgcta ggagcccatc ctgggtcaga ggccgatccg cagaaccaga 1380[2957] acgttttccc ctcctggact gttagtaact tagtctccct cctcccctaa ccacccccgc 1440[2958] ccccccccac cccccgcagt aataaaggcc cctgaacgtg tatgttggtc tcccgggagc 1500[2959] tgcttgctga agatccgcgc ccctgtcgcc gtctggtagg agctgtttgc agggtcctaa 1560[2960] ctcaatcggc ttgttgtgat gcgtatcccc gtagatgcca gcacgagccg ccgcttcacg 1620[2961] ccgccttcca ccgcgctgag cccaggcaag atgagcgagg cgttgccgct gggcgccccg 1680[2962] gacgccggcg ctgccctggc cggcaagctg aggagcggcg accgcagcat ggtggaggtg 1740[2963] ctggccgacc acccgggcga gctggtgcgc accgacagcc ccaacttcct ctgctccgtg 1800[2964] ctgcctacgc actggcgctg caacaagacc ctgcccatcg ctttcaaggt ggtggcccta 1860[2965] ggggatgttc cagatggcac tctggtcact gtgatggctg gcaatgatga aaactactcg 1920[2966] gctgagctga gaaatgctac cgcagccatg aagaaccagg ttgcaagatt taatgacctc 1980[2967] aggtttgtcg gtcgaagtgg aagagggaaa agcttcactc tgaccatcac tgtcttcaca 2040[2968] aacccaccgc aagtcgccac ctaccacaga gccatcaaaa tcacagtgga tgggccccga 2100[2969] gaacctcgaa gacatcggca gaaactagat gatcagacca agcccgggag cttgtccttt 2160[2970] tccgagcggc tcagtgaact ggagcagctg cggcgcacag ccatgagggt cagcccacac 2220[2971] cacccagccc ccacgcccaa ccctcgtgcc tccctgaacc actccactgc ctttaaccct 2280[2972] cagcctcaga gtcagatgca ggatacaagg cagatccaac catccccacc gtggtcctac 2340[2973] gatcagtcct accaatacct gggatccatt gcctctcctt ctgtgcaccc agcaacgccc 2400[2974] atttcacctg gacgtgccag cggcatgaca accctctctg cagaactttc cagtcgactc 2460[2975] tcaacggcac ccgacctgac agcgttcagc gacccgcgcc agttccccgc gctgccctcc 2520[2976] atctccgacc cccgcatgca ctatccaggc gccttcacct actccccgac gccggtcacc 2580[2977] tcgggcatcg gcatcggcat gtcggccatg ggctcggcca cgcgctacca cacctacctg 2640[2978] ccgccgccct accccggctc gtcgcaagcg cagggaggcc cgttccaagc cagctcgccc 2700[2979] tcctaccacc tgtactacgg cgcctcggcc ggctcctacc agttctccat ggtgggcggc 2760[2980] gagcgctcgc cgccgcgcat cctgccgccc tgcaccaacg cctccaccgg ctccgcgctg 2820[2981] ctcaacccca gcctcccgaa ccagagcgac gtggtggagg ccgagggcag ccacagcaac 2880[2982] tcccccacca acatggcgcc ctccgcgcgc ctggaggagg ccgtgtggag gccctactga 2940[2983] ggcgccaggc ctggcccggc tgggccacgc gggccgccgc cttcgcctcc gggcgcgcgg 3000[2984] gcctcctgtt cgcgacaagc ccgccgggat cccgggccct gggcccggcc accgtcctgg 3060[2985] ggccgagggc gcccgacggc caggatctcg ctgtaggtca ggcccgcgca gcctcctgcg 3120[2986] cccagaagcc cacgccgccg ccgtctgctg gcgccccggc cctcgcggag gtgtccgagg 3180[2987] cgacgcacct cgagggtgtc cgccggcccc agcacccagg ggacgcgctg gaaagcaaac 3240[2988] aggaagattc ccggagggaa actgtgaatg cttctgattt agcaatgctg tgaataaaaa 3300[2989] gaaagatttt atacccttga cttaactttt taaccaagtt gtttattcca aagagtgtgg 3360[2990] aattttggtt ggggtggggg gagaggaggg atgcaactcg ccctgtttgg catctaattc 3420[2991] ttatttttaa tttttccgca ccttatcaat tgcaaaatgc gtatttgcat ttgggtggtt 3480[2992] tttattttta tatacgttta tataaatata tataaattga gcttgcttct ttcttgcttt 3540[2993] gaccatggaa agaaatatga ttcccttttc tttaagtttt atttaacttt tcttttggac 3600[2994] ttttgggtag ttgttttttt ttgttttgtt ttgttttttt gagaaacagc tacagctttg 3660[2995] ggtcattttt aactactgta ttcccacaag gaatccccag atatttatgt atcttgatgt 3720[2996] tcagacattt atgtgttgat aattttttaa ttatttaaat gtacttatat taagaaaaat 3780[2997] atcaagtact acattttctt ttgttcttga tagtagccaa agttaaatgt atcacattga 3840[2998] agaaggctag aaaaaaagaa tgagtaatgt gatcgcttgg ttatccagaa gtattgttta 3900[2999] cattaaactc cctttcatgt taatcaaaca agtgagtagc tcacgcagca acgtttttaa 3960[3000] taggattttt agacactgag ggtcactcca aggatcagaa gtatggaatt ttctgccagg 4020[3001] ctcaacaagg gtctcatatc taacttcctc cttaaaacag agaaggtcaa tctagttcca 4080[3002] gagggttgag gcgggtgcca ataattacat ctttggagag gatttgattt ctgcccaggg 4140[3003] atttgctcac cccaaggtca tctgataatt tcacagatgc tgtgtaacag aacacagcca 4200[3004] aagtaaactg tgtaggggag ccacatttac ataggaacca aatcaatgaa tttaggggtt 4260[3005] acgattatag caatttaagg gccaccagaa gcaggcctcg aggagtcaat ttgcctctgt 4320[3006] gtgcctcagt ggagacaagt gggaaaacat ggtcccacct gtgcgagacc ccctgtcctg 4380[3007] tgctgctcac tcaacaacat ctttgtgttg ctttcaccag gctgagaccc taccctatgg 4440[3008] ggtatatggg cttttacctg tgcaccagtg tgacaggaaa gattcatgtc actactgtcc 4500[3009] gtggctacaa ttcaaaggta tccaatgtcg ctgtaaattt tatggcacta tttttattgg 4560[3010] aggatttggt cagaatgcag ttgttgtaca actcataaat actaactgct gattttgaca 4620[3011] catgtgtgct ccaaatgatc tggtggttat ttaacgtacc tcttaaaatt cgttgaaacg 4680[3012] atttcaggtc aactctgaag agtatttgaa agcaggactt cagaacagtg tttgattttt 4740[3013] attttataaa tttaagcatt caaattaggc aaatctttgg ctgcaggcag caaaaacagc 4800[3014] tggacttatt taaaacaact tgtttttgag ttttcttata tatatattga ttatttgttt 4860[3015] tacacacatg cagtagcact ttggtaagag ttaaagagta aagcagctta tgttgtcagg 4920[3016] tcgttcttat ctagagaaga gctatagcag atctcggaca aactcagaat atattcactt 4980[3017] tcatttttga caggattccc tccacaactc agtttcatat attattccgt attacatttt 5040[3018] tgcagctaaa ttaccataaa atgtcagcaa atgtaaaaat ttaatttctg aaaagcacca 5100[3019] ttagcccatt tcccccaaat taaacgtaaa tgtttttttt cagcacatgt taccatgtct 5160[3020] gacctgcaaa aatgctggag aaaaatgaag gaaaaaatta tgtttttcag tttaattctg 5220[3021] ttaactgaag atattccaac tcaaaaccag cctcatgctc tgattagata atcttttaca 5280[3022] ttgaaccttt actctcaaag ccatgtgtgg agggggcttg tcactattgt aggctcactg 5340[3023] gattggtcat ttagagtttc acagactctt accagcatat atagtattta attgtttcaa 5400[3024] aaaaaatcaa actgtagttg ttttggcgat aggtctcacg caacacattt ttgtatgtgt 5460[3025] gtgtgtgtgc gtgtgtgtgt gtgtgtgtga aaaattgcat tcattgactt caggtagatt 5520[3026] aaggtatctt tttattcatt gccctcagga aagttaaggt atcaatgaga cccttaagcc 5580[3027] aatcatgtaa taactgcatg tgtctggtcc aggagaagta ttgaataagc catttctact 5640[3028] gcttactcat gtccctattt atgatttcaa catggataca tatttcagtt ctttcttttt 5700[3029] ctcactatct gaaaatacat ttccctccct ctcttccccc caatatctcc ctttttttct 5760[3030] ctcttcctct atcttccaaa ccccactttc tccctcctcc ttttcctgtg ttctcttaag 5820[3031] cagatagcac atacccccac ccagtaccaa atttcagaac acaagaaggt ccagttcttc 5880[3032] ccccttcaca taaaggaaca tggtttgtca gcctttctcc tgtttatggg tttcttccag 5940[3033] cagaacagag acattgccaa ccatattgga tctgcttgct gtccaaacca gcaaacttcc 6000[3034] tgggcaaatc acaatcagtg agtaaataga cagcctttct gctgccttgg gtttctgtgc 6060[3035] agataaacag aaatgctctg attagaaagg aaatgaatgg ttccactcaa atgtcctgca 6120[3036] atttaggatt gcagatttct gccttgaaat acctgtttct ttgggacatt ccgtcctgat 6180[3037] gatttttatt tttgttggtt tttatttttg gggggaatga catgtttggg tcttttatac 6240[3038] atgaaaattt gtttgacaat aatctcacaa aacatatttt acatctgaac aaaatgcctt 6300[3039] tttgtttacc gtagcgtata catttgtttt gggatttttg tgtgtttgtt gggaattttg 6360[3040] tttttagcca ggtcagtatt gatgaggctg atcatttggc tctttttttc cttccagaag 6420[3041] agttgcatca acaaagttaa ttgtatttat gtatgtaaat agattttaag cttcattata 6480[3042] aaatattgtt aatgcctata actttttttc aatttttttg tgtgtgtttc taaggacttt 6540[3043] ttcttaggtt tgctaaatac tgtagggaaa aaatgcttct ttctaacttt gtttatttta 6600[3044] gactttaaaa tgagctactt cttattcact tttgtaaaca gctaatagca tggttccaat 6660[3045] tttttttaag ttcacttttt ttgttctagg ggaaatgaat gtgcaaaaaa agaaaaagaa 6720[3046] ctgttggtta tttgtgttat tctggatgta taaaaatcaa tggaaaaaaa taaactttca 6780[3047] aattgaaatg acggtataac acatctactg aaaaagcaac gggaaatgtg gtcctattta 6840[3048] agccagcccc cacctagggt ctatttgtgt ggcagttatt gggtttggtc acaaaacatc 6900[3049] ctgaaaattc gtgcgtgggc ttctttctcc ctggtacaaa cgtatggaat gcttcttaaa 6960[3050] ggggaactgt caagctggtg tcttcagcca gatgacatga gagaatatcc cagaaccctc 7020[3051] tctccaaggt gtttctagat agcacaggag agcaggcact gcactgtcca cagtccacgg 7080[3052] tacacagtcg ggtgggccgc ctcccctctc ctgggagcat tcgtcgtgcc cagcctgagc 7140[3053] agggcagctg gactgctgct gttcaggagc caccagagcc ttcctctctt tgtaccacag 7200[3054] tttcttctgt aaatccagtg ttacaatcag tgtgaatggc aaataaacag tttgacaagt 7260[3055] acata 7265[3056] <210>67

[3057] <211>4221

[3058] <212>DNA

[3059] <213>人

[3060] <400>67

[3061] gtcggccgtc ccctttaatt tttaaataca cggtcccctc ttttctctgg ggggggcaag 60[3062] caagaaatca aagaaggagg agacaagccg tcaattttct ccaaaacaaa ccccaccggg 120[3063] caatttggtc tcggggtagg gggagacggg gtgattgcaa attattccag gacgagatcc 180[3064] agttctccag cgggaaaggg gcaaaggaac gccgcgcgtt ggaagggcca gggtacgcag 240[3065] ctccccttgc agcgcccgca ggacccccgc aagctcgtgc cggcgaaatc ggagaccgcc 300[3066] gatctgtcct cgttctctcc tgcacgtctg gctgcattcg gaggaagacc tggggcgcga 360[3067] gcgagcggcg acagcatgag cctgtgctga cctccgcgcg gcgggccgag cccagggctt 420[3068] tgtcgcggta cctgcgccca gcccgcgccg caactctgtg cccagctttt gcaatctttt 480[3069] gttgcagcgc tgaccgcacc aagttaaatg ctcccttgca atttttcttt tttttgtttg 540[3070] tttgtttaat ttttggagag ctcgcgatct tggaaaagcc tcagacgcca tctacagtta 600[3071] aaacgtaggt aactgccctc tcccgcaccc cccccttaca cgccccccac cctttccacc 660[3072] aaaaaaaggg ggtgcagcgc ggattctggc tgccgtgcgt cgccagccgg tagacccgtg 720[3073] cttgtttcct ttctcttttt gtttggcttc taacgcgttg ggactgagtc gccgccgtga 780[3074] gctccccgaa gactgcacaa actaccgcgg gctcctccgc cccgtctgcg attcggaagc 840[3075] cggcctgggg gtcgcgtcgg gagccctgcg ctgcagctcc gcaccttagc agcccgggta 900[3076] ctcatccaga tccacgccgg ggacacacac acagagtaac taaaagtgcg gcgattctgc 960[3077] acatcgccga ctgctttggg gtaacaaaaa gacccgagtt gcctgccgac cgaggacccc 1020[3078] cgggagccgg gctcggagca gacgaggtat ccggcggcgc ccatttgggg gcttctaact 1080[3079] ctttctccac gcagcccctc ttctgtcccc tcccctctcg ctccctttta aaatcagtgg 1140[3080] caccgaggcg cctgcagccg cactcgccag cgactcatct ctccagcggg tttttttttg 1200[3081] tttgtcgtgt gcgatcctca cactcatgaa catacacagg tctaccccca tcacaatagc 1260[3082] gagatatggg agatcgcgga acaaaaccca ggatttcgaa gagttgtcgt ctataaggtc 1320[3083] cgcggagccc agccagagtt tcagcccgaa cctcggctcc ccgagcccgc ccgagactcc 1380[3084] gaacttgtcg cattgcgttt cttgtatcgg gaaatactta ttgttggaac ctctggaggg 1440[3085] agaccacgtt tttcgtgccg tgcatctgca cagcggagag gagctggtgt gcaaggtgtt 1500[3086] tgatatcagc tgctaccagg aatccctggc accgtgcttt tgcctgtctg ctcatagtaa 1560[3087] catcaaccaa atcactgaaa ttatcctggg tgagaccaaa gcctatgtgt tctttgagcg 1620[3088] aagctatggg gacatgcatt ccttcgtccg cacctgcaag aagctgagag aggaggaggc 1680[3089] agccagactg ttctaccaga ttgcctcggc agtggcccac tgccatgacg gggggctggt 1740[3090] gctgcgggac ctcaagctgc ggaaattcat ctttaaggac gaagagagga ctcgggtcaa 1800[3091] gctggaaagc ctggaagacg cctacattct gcggggagat gatgattccc tctccgacaa 1860[3092] gcatggctgc ccggcttacg taagcccaga gatcttgaac accagtggca gctactcggg 1920[3093] caaagcagcc gacgtgtgga gcctgggggt gatgctgtac accatgttgg tggggcggta 1980[3094] ccctttccat gacattgaac ccagctccct cttcagcaag atccggcgtg gccagttcaa 2040[3095] cattccagag actctgtcgc ccaaggccaa gtgcctcatc cgaagcattc tgcgtcggga 2100[3096] gccctcagag cggctgacct cgcaggaaat tctggaccat ccttggtttt ctacagattt 2160[3097] tagcgtctcg aattcagcat atggtgctaa ggaagtgtct gaccagctgg tgccggacgt 2220[3098] caacatggaa gagaacttgg accctttctt taactgagct catgccccac ggagacttag 2280[3099] caggttccag gagtgagcga gggcagcgga aaggagttct tccgggggac acgaattgcc 2340[3100] tggctgagta gcaagaaaga cacactctta agtttcttgg ttcagagcag gaaaaccttc 2400[3101] aaggagctga ctgaccacgt agcatggggg caagaggcgt gggatgggga ttggggtgag 2460[3102] atggatggga gcccgctgga gcttgtcttc cctaacatag cctgggagac caccccttgc 2520[3103] cacttgggcc acttccgcct accccacttt tcattttgtt ccaaaatagt tgcagatcct 2580[3104] gacagaatca aaactctctg cctcaaacac acatcctggc atcgcactgt tagcatttaa 2640[3105] cttcttgtta ggattcaggg aaggaacagt tggccaagaa ttttttttct tttaaacaag 2700[3106] ccaaccacct agctggtaat taatgaggtt cacttaaaaa aaaaattcgg tgcacacaga 2760[3107] ctgacatgaa acctgggtgc tacagtaaaa gaaaacaaaa gtccagtttg tgtctcttaa 2820[3108] tcgctcactt caactcattt cttctaaata aactatttaa tatcctggtc aggaaatgac 2880[3109] atgttaatgc tttgctccct gaagggggaa aaaatctgtc ctttaacaag ctattctgtt 2940[3110] ttgtgtcaat tgggtccgtg gcaaggaagc tattaggaag tcaaacggtc caggatgcat 3000[3111] tacctgctaa tccttaggtt taaaggggga aagaaaaggg aagaagaaag gaaaagagaa 3060[3112] atccaactcc tttttcatgt tttgcttttg aacaatgagg gtttgtgtga caggcattcc 3120[3113] tctttgctga gatgatagca atggcctgag attttagcaa gctcctggag tctgatgctt 3180[3114] ttgcagtact ctgatcgcaa ctaaacattt gtctttgttt tattagaaac tagtgaaaca 3240[3115] aagcaggttg tcccacatgt ataaaataca gggcagctat ttagttttct ttacagagaa 3300[3116] tgatcctttt aaggcttgta aggccctctg gtttggacaa aaaccctcag tagagacaag 3360[3117] cgggaaggat aattagctga aagctatgat gatataaata aaaacagctc tctatcccaa 3420[3118] tacgcacctt tgtattttca agaactcttc tatttattaa ggaaaatgtc acattgtgat 3480[3119] gtattaagcc agtacttcaa ttacgggttg acttgggatg acatattaca tgctgtagtt 3540[3120] aacatttata attctttttc cttgtttgag tatttctgtc tctgaaataa ccttttactt 3600[3121] ggcttttcta gatagcttta tttgatttcg agtggcaaaa tgttttttat tacggctttt 3660[3122] ctattgctgt atgatacaga actcttttgg cataaatatt tgtgttccca gtacctcact 3720[3123] tgttcggatt tgactgcctg tatatgtttt gtgaaatggt cctgtttttg ggtaggtgac 3780[3124] acgtggactc tagtatgtaa atgttacttg aatctgtgct tcataatagt gtgtggcatg 3840[3125] tatgtgcaga ctcttggatg ctttatgcct gcgcaccagg agccctgtcc tcacgttccc 3900[3126] aggagggcgg cttcaccctt cgtaaccagg agacaaggcg gccatggatt tgcccttgat 3960[3127] tctattttgc taatggaaga tagaaaggag agaaggtttt tttttttttt taacattctg 4020[3128] aagatggtgc tgtgtcaaga aggacctttt ttttcccctc tcccctattt tttaagtacc 4080[3129] ttggaggagg agaggttggt gacatgcatg gtggggatct atggcctctg gtgctttgtc 4140[3130] ctgtatttgg tttaatgttt ttgtcctaat ctcttcaatc aataaaattg tgcgtattta 4200[3131] actaaaaaaa aaaaaaaaaa a 4221[3132] <210>68

[3133] <211>524

[3134] <212>DNA

[3135] <213>人

[3136] <400>68

[3137] ccctgccttc caccttggaa gaggaggctg gacgcatcag cagtggccag gcaggtcgca 60[3138] aaatctccca gcctagagac cacacctgaa acggctgaag ccagcttgca caagggctgc 120[3139] tgtccctctg cggcaggcag agctggtggg ggcaggggtc acagagcagt catagacacc 180[3140] atggaccagg caggagaagg gcagatggca catgggcaca acagggcctt gtccttagag 240[3141] cactgggggg tcatggctgg gaggggcatg gcaggggctg gcatccctgt agagccagag 300[3142] gggccaccca ggcagtgaca ttccagatat gttgggctca cctcatcctt gctgtgagac 360[3143] tggagttcca tggggacatg aagtcagtac accgcagagc tgctcagctg ctctacctct 420[3144] cgctgacttt tttgttgcac atatacattt tctttcaatt agcatttatt tcagctttta 480[3145] tttaagcttt ttgacagtac atgtaaatat atgattataa ccat 524[3146] <210>69

[3147] <211>4151

[3148] <212>DNA

[3149] <213>人

[3150] <400>69

[3151] gggaatagca gaataggagc aagccagcac tagtcagcta actaagtgac tcaaccaagg 60[3152] ccttttttcc ttgttatctt tgcagatact tcattttctt agcgtttctg gagattacaa 120[3153] catcctgcgg ttccgtttct gggaacttta ctgatttatc tcccccctca cacaaataag 180[3154] cattgattcc tgcatttctg aagatctcaa gatctggact actgttgaaa aaatttccag 240[3155] tgaggctcac ttatgtctgt aaagatggga aaaaaataca agaacattgt tctactaaaa 300[3156] ggattagagg tcatcaatga ttatcatttt agaatggtta agtccttact gagcaacgat 360[3157] ttaaaactta atttaaaaat gagagaagag tatgacaaaa ttcagattgc tgacttgatg 420[3158] gaagaaaagt tccgaggtga tgctggtttg ggcaaactaa taaaaatttt cgaagatata 480[3159] ccaacgcttg aagacctggc tgaaactctt aaaaaagaaa agttaaaagt aaaaggacca 540[3160] gccctatcaa gaaagaggaa gaaggaagtg catgctactt cacctgcacc ctccacaagc 600[3161] agcactgtca aaactgaagg agcagaggca actcctggag ctcagaaaag aaaaaaatca 660[3162] accaaagaaa aggctggacc caaagggagt aaggtgtccg aggaacagac tcagcctccc 720[3163] tctcctgcag gagccggcat gtccacagcc atgggccgtt ccccatctcc caagacctca 780[3164] ttgtcagctc cacccaacag ttcttcaact gagaacccga aaacagtggc caaatgtcag 840[3165] gtaactccca gaagaaatgt tctccaaaaa cgcccagtga tagtgaaggt actgagtaca 900[3166] acaaagccat ttgaatatga gaccccagaa atggagaaaa aaataatgtt tcatgctaca 960[3167] gtggctacac agacacagtt cttccatgtg aaggttttaa acaccagctt gaaggagaaa 1020[3168] ttcaatggaa agaaaatcat catcatatca gattatttgg aatatgatag tctcctagag 1080[3169] gtcaatgaag aatctactgt atctgaagct ggtcctaacc aaacgtttga ggttccaaat 1140[3170] aaaatcatca acagagcaaa ggaaactctg aagattgata ttcttcacaa acaagcttca 1200[3171] ggaaatattg tatatggggt atttatgcta cataagaaaa cagtaaatca gaagaccaca 1260[3172] atctacgaaa ttcaggatga tagaggaaaa atggatgtag tggggacagg acaatgtcac 1320[3173] aatatcccct gtgaagaagg agataagctc cagcttttct gctttcgact tagaaaaaag 1380[3174] aaccagatgt caaaactgat ttcagaaatg catagtttta tccagataaa gaaaaaaaca 1440[3175] aacccgagaa acaatgaccc caagagcatg aagctacccc aggaacagcg tcagcttcca 1500[3176] tatccttcag aggccagcac aaccttccct gagagccatc ttcggactcc tcagatgcca 1560[3177] ccaacaactc catccagcag tttcttcacc aagaaaagtg aagacacaat ctccaaaatg 1620[3178] aatgacttca tgaggatgca gatactgaag gaagggagtc attttccagg accgttcatg 1680[3179] accagcatag gcccagctga gagccatccc cacactcctc agatgcctcc atcaacacca 1740[3180] agcagcagtt tcttaaccac gttgaaacca agactgaaga ctgaacctga agaagtttcc 1800[3181] atagaagaca gtgcccagag tgacctcaaa gaagtgatgg tgctgaacgc aacagaatca 1860[3182] tttgtatatg agcccaaaga gcagaagaaa atgtttcatg ccacagtggc aactgagaat 1920[3183] gaagtcttcc gagtgaaggt ttttaatatt gacctaaagg agaagttcac cccaaagaag 1980[3184] atcattgcca tagcaaatta tgtttgccgc aatgggttcc tggaggtata tcctttcaca 2040[3185] cttgtggctg atgtgaatgc tgaccgaaac atggagatcc caaaaggatt gattagaagt 2100[3186] gccagcgtaa ctcctaaaat caatcagctt tgctcacaaa ctaaaggaag ttttgtgaat 2160[3187] ggggtgtttg aggtacataa ggtaagccca caccattgtt ttataaaatt tctcctgcaa 2220[3188] cctccaattt ttaaagtctt aacttgtcaa ctggagtttg gtcaacttac tcaacacaga 2280[3189] aaatcaaccc cttcaccctt cccccagcac tagagataat tgaatagagt tcatttcagg 2340[3190] atatggggta cgttatattg taacattcct cttcttaagg tatcatcatg caagttattt 2400[3191] agacagtcac taggaaactt ggcattttat tagttttgat gatctattca gagccaccct 2460[3192] tgtccaggac agtgcagagt ttatatcaac acacatatcc ttaggatttt gtttctttga 2520[3193] gttcttctcc atctgtatca atgacaactt aatttaattg tgaataaaag agttgctctc 2580[3194] ccaagcctga atcctgattg tgacaaccag agtaagaaat aaaatagact actctgcttt 2640[3195] agaatgcagc tatgtctaac agttagctag aattctgatc atttggactc caaagtttct 2700[3196] tgcctcttct cattcattaa ttcatcagga gactgtagag caactaactt ctgcattaaa 2760[3197] taataagaga aatacgaagc aaaaagacta aaaaagtcac gtagcttaac tgctcaattt 2820[3198] ataaatgggg caataaaatg caaaaaaaaa gaaaaaaagc ttggtgaatt cttaggctta 2880[3199] cagtgtgcct ttcagtctct acacatcatg taaatattat gcttagctga tttaacttct 2940[3200] tgtttgaagt actgtttcat actccattat acatgtcttc tagggtggct tacttttaat 3000[3201] tgtgctgttt tctctacact cagtttaaat gactgtacat atatatgtgg ttggagagtt 3060[3202] aatgaataat gagctacaaa ccagaacaat gtgactagat agataggatg atctagaatt 3120[3203] gagaactggc agattgggaa aagagtggct atatggagaa agaaagaaag tagttccata 3180[3204] ttgaaataac agtctactta atgaggaccg ttgcaacatt ctttctcaaa cttacaaagt 3240[3205] gccataaaaa gcctctattc tctgctcttg ggcaggtgtg aaagaaacct accaaattaa 3300[3206] tcagattttt ctgtatccag gctccttaaa aaatcccagc tgtgctgatg tggaaacagg 3360[3207] aagaattagg aaagtaatca attttttttc ctagaaaaaa tccagcagac aaagaacttc 3420[3208] aacaaaagag gctcaaggga ggagttgaaa ggcaggattc aaagaccaag tatcttaagc 3480[3209] tatttggtac ctgttattca ggacctacag ctctgtttac tctatcaaag accaaaagtt 3540[3210] tccagaaaca ccctgtattt ctcatagatt tgaaaattat tgatccagtt tcagaagata 3600[3211] agtgttaatt ttcttttgca gaaaaatgta aggggtgaat tcacttatta tgaaatacaa 3660[3212] gataatacag ggaagatgga agtggtggtg catggacgac tgaccacaat caactgtgag 3720[3213] gaaggagata aactgaaact cacctgcttt gaattggcac cgaaaagtgg gaataccggg 3780[3214] gagttgagat ctgtaattca tagtcacatc aaggtcatca agaccaggaa aaacaagaaa 3840[3215] gacatactca atcctgattc caagtatgga aacttcacca gactttttct tctaaaatct 3900[3216] ggatgtcatt gacgataatg tttatggaga taaggtctaa gtgcctaaaa aaatgtacat 3960[3217] atacctggtt gaaatacaac actatacata cacaccacca tatatactag ctgttaatcc 4020[3218] tatggaatgg ggtattggga gtgctttttt aatttttcat agtttttttt taataaaatg 4080[3219] gcatattttg catctacaac ttctataatt tgaaaaaata aataaacatt atcttttttg 4140[3220] tgaaaaaaaa a 4151[3221] <210>70

[3222] <211>741

[3223] <212>DNA

[3224] <213>人

[3225] <220>

[3226] <221>misc_feature

[3227] <222>(492)..(492)

[3228] <223>N EQUALS ANY KIND BASE

[3229] <220>

[3230] <221>misc_feature

[3231] <222>(652)..(652)

[3232] <223>N EQUALS ANY KIND BASE

[3233] <220>

[3234] <221>misc_feature

[3235] <222>(696)..(696)

[3236] <223>N EQUALS ANY KIND BASE

[3237] <220>

[3238] <221>misc_feature

[3239] <222>(707)..(707)

[3240] <223>N EQUALS ANY KIND BASE

[3241] <400>70

[3242] tttgcttttg tttcttctgg tcccatcact gggacctaaa agaagctcac atgtggtctc 60[3243] tggaaatgct gaagctgtgg actgtagaca ttattttcag tccttgtcct ggtggctgca 120[3244] taccagatgc tgctccttcc ctgtgtgtgg ccagctgtac acagtgacat gctcccaagg 180[3245] ccgcggcaca ggcggtgatg ggaactcctc cccgggccag cctctcaggc tgcagcccca 240[3246] cggcaccctg aggccctcat ctctgctcgg cagctaaaac atctccttct tcgatgctct 300[3247] gcaactgcag cctctggctc acaagagttc tgctgcctcg gcggcccccg aagccgcccc 360[3248] ccgggacagt ccgtgctgta accaagaccc ctggcaaagc ctcctcccca aataagttga 420[3249] ttttggcttc ggcctcaatg gctttggcca agcttgctgc gtaactgtcc aaggacttgt 480[3250] gtacttcagc tntcacatga agaatcgagt tcttggcagc ttctttgatt tgttccactt 540[3251] catcctcaaa tgtcaccgag ctccttctct ttggtgggca agtgcagtga gaagggaggg 600[3252] tgtcatcaga cgtgtgtcct caagcagcat catatctgtc cctgagtcct gngagcagct 660[3253] gaaaccagtg tcccccgtgc tgctgctgtg ccccangggc tgtccgnctg ccatgagcgc 720[3254] aatgagtgtg ggacaggccc c 741[3255] <210>71

[3256] <211>755

[3257] <212>DNA

[3258] <213>人

[3259] <220>

[3260] <221>misc_feature

[3261] <222>(643)..(643)

[3262] <223>N EQUALS ANY KIND BASE

[3263] <220>

[3264] <221>misc_feature

[3265] <222>(741)..(741)

[3266] <223>N EQUALS ANY KIND BASE

[3267] <400>71

[3268] tggtagtgaa tactttattt tgttgtaaac aagttagttt tgagggtatt tcctcgtggt 60[3269] cctcctgccg tcactcgtcc ccatgttcca atgatgctga tcaactgctt tattcagttt 120[3270] cccatctttc ttcttgccca ggcatcgtag cctttctttt tttaaacaca tgatccctag 180[3271] tactcatctt tggaggacaa aaggctttcc atatgttaga aaaatttgaa tctcatagta 240[3272] ctcacaacaa tgagcagcat tgtaagttgt gatgcattca tttggattgg aacattctca 300[3273] atcagtcctt ccactctaag taaatatttg tttctcacag aacacaaggc agttcaaaag 360[3274] gcctcttggt taaggaatta tagggtgttg aatgggaaac atcatacaag cagtgaaaac 420[3275] aaaaatcttt ccaggttgtc ggattttctc cttcttggtc ttataaaaag caactagaca 480[3276] tctctaattt aaaaaataca tgcacatata tacaatagtg attggaatgt attcttatcc 540[3277] aaaacattat agagtttatc tcagatatac tgagtactgt cactcagtct gtaaattacc 600[3278] cccaagaagg tgggttgttt cctcattcct taaataaaaa cangatcgaa taacagacca 660[3279] aaaagaagtt actaaatttt aacactgaca tccttgtgaa gagccagtct ttacaggcgt 720[3280] ttgtaaagta gactgtgggg nagtgtacac taata 755[3281] <210>72

[3282] <211>1894

[3283] <212>DNA

[3284] <213>人

[3285] <400>72

[3286] aggactcggg ccggagcgtg gccggacccc cacccgccga ggggcccagg gaggacgcgg 60[3287] cagagtcacg gtggcagcat tgagagttgg acacccgggt ccttgaagtg atctctaggc 120[3288] cccagcccca aatccgccac cattccgtgc tgcggggaca ccatggctcc agaagaggac 180[3289] gctggagggg aggccttagg gggcagtttc tgggaggctg gcaactacag gcgcacggta 240[3290] cagcgggtgg aggacgggca ccggctgtgc ggggacctgg tcagctgctt ccaggagcgc 300[3291] gcccgcatcg agaaggctta tgcccagcag ttggctgact gggcccgaaa gtggaggggg 360[3292] accgtggaga agggccccca gtatggcaca ctggagaagg cctggcatgc ctttttcacg 420[3293] gcggctgagc ggctgagcgc gctgcacctg gaggtgcggg agaagctgca agggcaggac 480[3294] agtgagcggg tgcgcgcctg gcagcggggg gctttccacc ggcctgtgct gggcggcttc 540[3295] cgcgagagcc gggcggccga ggacggcttc cgcaaggccc agaagccctg gctgaagagg 600[3296] ctgaaggagg ttgaggcttc caagaaaagc taccacgcag cccggaagga tgagaagacc 660[3297] gcccagacga gggagagcca cgcaaaggca gacagcgccg tctcccagga gcagctgcgc 720[3298] aaactgcagg aacgggtgga acgctgtgcc aaggaggccg agaagacaaa agctcagtat 780[3299] gagcagacgc tggcagagct gcatcgctac actccacgct acatggagga catggaacag 840[3300] gcctttgaga cctgccaggc cgccgagcgc cagcggcttc ttttcttcaa ggatatgctg 900[3301] ctcaccttac accagcacct ggacctttcc agcagtgaga agttccatga actccaccgt 960[3302] gacttgcacc agggcattga ggcagccagt gacgaagagg atctgcgctg gtggcgcagc 1020[3303] acccacgggc caggcatggc catgaactgg ccacagttcg aggagtggtc cttggacaca 1080[3304] cagaggacaa tcagccggaa agagaagggt ggccggagcc ctgatgaggt taccctgacc 1140[3305] agcattgtgc ctacaagaga tggcaccgca cccccacccc agtccccggg gtccccaggc 1200[3306] acggggcagg atgaggagtg gtcagatgaa gagagtcccc ggaaggctgc caccggggtt 1260[3307] cgggtgaggg cactctatga ctacgctggc caggaagctg atgagctgag cttccgagca 1320[3308] ggggaggagc tgctgaagat gagtgaggag gacgagcagg gctggtgcca aggccagttg 1380[3309] cagagtggcc gcattggcct gtaccctgcc aactacgtgg agtgtgtggg cgcctgagtg 1440[3310] tcctgacagc ccttctgcaa cgtttaccca ccctggttca gagcccagct tctcctggag 1500[3311] agccggaccc tcagggccct gaaccgtcgc tctctggctg ctcctctgtc ccttgaggga 1560[3312] ggaagtcctg ggacccaggg aggggagggg cctttgtcta gggaagggac tggtagggaa 1620[3313] gggacgagtc taggctgagg gcaagatggg aggtcagagg tgacagaagc gttcaggggt 1680[3314] gcctgggcct ccccaggagc tgtggactca gttcctgacc tctgctttgg ggttcctggg 1740[3315] gtgggcttgg ggtgagtgta gttctggcct agcagcaccc tcttgtggct tgttctagcg 1800[3316] tgtattaaaa cttgacacac acccacacac aaaaccaaaa aaaaaaaaaa aaaaaaaaaa 1860[3317] aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaa 1894[3318] <210>73

[3319] <211>649

[3320] <212>DNA

[3321] <213>人

[3322] <400>73

[3323] ggcgaggcgt ctcggagtct cagagacacc aaggcccctg cgacaaggtg gctgcagcta 60[3324] ggccgggggc gtcaggacga cggagcgggt tcgggtcggt gacacgcaga cctgagggag 120[3325] ctgggcccgc cttttccgcc cgcgccccag gcccttgcag atcgagattt gcgtcctaga 180[3326] gtgggaaaaa agcagaggcc agggcgccga ttttatttgg agagaagcaa gcatctttgc 240[3327] ctctttggag taggaaattc agacttgaaa aagtggtgtg tggttgactc tgtttctcgc 300[3328] catgtcttct cacaagactt tcaccattaa gcgattcctg gccaagaaac aaaagcaaaa 360[3329] tcgtcccatc ccccagtgga ttcagatgaa acctggtagt aaaatcaggt acaactccaa 420[3330] aaggaggcat tggagaagaa ccaagctggg tctataagga attgcacatg agatggcaca 480[3331] catatttatg ctgtatcaag ttcacgatca tcttacgata tcaagctgaa aatgtcacca 540[3332] ctacctggac agttgcacat gttttactgg gaatattttt ttctgttttt ctgtatgctc 600[3333] tgtgctagta gggtggattc agtaataaat atgtgaaagc ttttgtttc 649[3334] <210>74

[3335] <211>1561

[3336] <212>DNA

[3337] <213>人

[3338] <400>74

[3339] gcggcgcgga gggcgcgggc ccgggagcca gggagcgagc ggggcgcccg gcagcgcgga 60[3340] gtcagcgccg cgggggccgc acccgactcg cgcctggaca ctcgcggggc gccgacctgg 120[3341] cagggggcca aaccagtgct cctgccacct ctctggctgc cccctagagc ctgcccatcc 180[3342] cagcctgacc aatgtccaca gccagggagc agccaatctt cagcacacgg gcgcacgtgt 240[3343] tccaaattga cccagccacc aagcgaaact ggatcccagc gggcaagcac gcactcactg 300[3344] tctcctattt ctacgatgcc acccgcaatg tgtaccgcat catcagcatc ggaggcgcca 360[3345] aggccatcat caacagcact gtcactccca acatgacctt caccaaaact tcccagaagt 420[3346] tcgggcagtg ggccgacagt cgcgccaaca cagtctacgg cttgggcttt gcctctgaac 480[3347] agcatctgac acagtttgcc gagaagttcc aggaagtgaa ggaagcagcc aggctggcca 540[3348] gggagaaatc tcaggatggc ggggagctca ccagtccagc cctggggctc gcctcccacc 600[3349] aggtgccccc gagccctctc gtcagtgcca acggccccgg cgaggaaaaa ctgttccgca 660[3350] gccagagcgc tgatgccccc ggccccacag agcgcgagcg gctaaagaag atgttgtctg 720[3351] agggctccgt gggcgaggta cagtgggagg ccgagttttt cgcactgcag gacagcaaca 780[3352] acaagctggc aggcgccctg cgagaggcca acgccgccgc agcccagtgg aggcagcagc 840[3353] tggaggctca gcgtgcagag gccgagcggc tgcggcagcg ggtggctgag ctggaggctc 900[3354] aggcagcttc agaggtgacc cccaccggtg agaaggaggg gctgggccag ggccagtcgc 960[3355] tggaacagct ggaagctctg gtgcaaacca aggaccagga gattcagacc ctgaagagtc 1020[3356] agactggggg gccccgcgag gccctggagg ctgccgagcg tgaggagact cagcagaagg 1080[3357] tgcaggacct ggagacccgc aatgcggagt tggagcacca gctgcgggcg atggagcgca 1140[3358] gcctggagga ggcacgggca gagcgggagc gggcgcgggc tgaggtgggc cgggcagcgc 1200[3359] agctgctgga cgtcaggctg tttgagctga gtgagctgcg tgagggcctg gcccgcctgg 1260[3360] ctgaggctgc gccctgagcc ggggctggtt ttctatgaac gattccggcc tgggatgcgg 1320[3361] gccaggctgc aggcggcata gttgggccca ttcgtcctgg aaagggactg gggggtccca 1380[3362] acttagccct gggtgggccg ggccgggctg ggctggggtg ggccccagtc ggctctggtt 1440[3363] gttggcagct ttggggctgt ttttgagctt ctcattgtgt agaatttcta gatcccccga 1500[3364] ttacatttct aagcgtgaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa 1560[3365] a 1561[3366] <210>75

[3367] <211>1188

[3368] <212>DNA

[3369] <213>人

[3370] <400>75

[3371] tcgagatcca ttgtgctcta aaggctcgcc ctcctgtgca tcgcggctaa tttggggtat 60[3372] cactgagctg aagacaaaga gaagggggag aaaacctagc agaccaccat gtgctatggg 120[3373] aagtgtgcac gatgcatcgg acattctctg gtggggctcg ccctcctgtg catcgcggct 180[3374] aatattttgc tttactttcc caatggggaa acaaagtatg cctccgaaaa ccacctcagc 240[3375] cgcttcgtgt ggttcttttc tggcatcgta ggaggtggcc tgctgatgct cctgccagca 300[3376] tttgtcttca ttgggctgga acaggatgac tgctgtggct gctgtggcca tgaaaactgt 360[3377] ggcaaacgat gtgcgatgct ttcttctgta ttggctgctc tcattggaat tgcaggatct 420[3378] ggctactgtg tcattgtggc agcccttggc ttagcagaag gaccactatg tcttgattcc 480[3379] ctcggccagt ggaactacac ctttgccagc accgagggcc agtaccttct ggatacctcc 540[3380] acatggtccg agtgcactga acccaagcac attgtggaat ggaatgtatc tctgttttct 600[3381] atcctcttgg ctcttggtgg aattgaattc atcttgtgtc ttattcaagt aataaatgga 660[3382] gtgcttggag gcatatgtgg cttttgctgc tctcaccaac agcaatatga ctgctaaaag 720[3383] aaccaaccca ggacagagcc acaatcttcc tctatttcat tgtaatttat atatttcact 780[3384] tgtattcatt tgtaaaactt tgtattagtg taacatactc cccacagtct acttttacaa 840[3385] acgcctgtaa agactggcat cttcacagga tgtcagtgtt taaatttagt aaacttcttt 900[3386] tttgtttgtt tatttgtgta acatactccc cacagtctac ttttacaaac gcctgtaaag 960[3387] actggcatct tcacaggatg tcagtgttta aatttagtaa acttcttttt tgtttgttta 1020[3388] tttgtttttg ttttttttta aggaatgagg aaacaaacca ccctctgggg gtagtttaca 1080[3389] gactgagtga cagtactcag tatatctgag ataaactcta taatgttttg gataaaaata 1140[3390] acattccatg gcacatatat acaatagtga ttggctttag agcacaat 1188[3391] <210>76

[3392] <211>1075

[3393] <212>DNA

[3394] <213>人

[3395] <400>76

[3396] cgcagcaaac acatccgtag aaggcagcgc ggccgccgag agccgcagcg ccgctcgccc 60[3397] gccgcccccc accccgccgc cccgcccggc gaattgcgcc ccgcgcccct cccctcgcgc 120[3398] ccccgagaca aagaggagag aaagtttgcg cggccgagcg gggcaggtga ggagggtgag 180[3399] ccgcgcggga ggggcccgcc tcggccccgg ctcagccccc gcccgcgccc ccagcccgcc 240[3400] gccgcgagca gcgcccggac cccccagcgg cggcccccgc ccgcccagcc ccccggcccg 300[3401] ccatgggcgc cgcggcccgc accctgcggc tggcgctcgg cctcctgctg ctggcgacgc 360[3402] tgcttcgccc ggccgacgcc tgcagctgct ccccggtgca cccgcaacag gcgttttgca 420[3403] atgcagatgt agtgatcagg gccaaagcgg tcagtgagaa ggaagtggac tctggaaacg 480[3404] acatttatgg caaccctatc aagaggatcc agtatgagat caagcagata aagatgttca 540[3405] aagggcctga gaaggatata gagtttatct acacggcccc ctcctcggca gtgtgtgggg 600[3406] tctcgctgga cgttggagga aagaaggaat atctcattgc aggaaaggcc gagggggacg 660[3407] gcaagatgca catcaccctc tgtgacttca tcgtgccctg ggacaccctg agcaccaccc 720[3408] agaagaagag cctgaaccac aggtaccaga tgggctgcga gtgcaagatc acgcgctgcc 780[3409] ccatgatccc gtgctacatc tcctccccgg acgagtgcct ctggatggac tgggtcacag 840[3410] agaagaacat caacgggcac caggccaagt tcttcgcctg catcaagaga agtgacggct 900[3411] cctgtgcgtg gtaccgcggc gcggcgcccc ccaagcagga gtttctcgac atcgaggacc 960[3412] cataagcagg cctccaacgc ccctgtggcc aactgcaaaa aaagcctcca agggtttcga 1020[3413] ctggtccagc tctgacatcc cttcctggaa acagcatgaa taaaacactc atccc 1075[3414] <210>77

[3415] <211>1358

[3416] <212>DNA

[3417] <213>人

[3418] <400>77

[3419] gcgacccggg gcgtttgcag cggtgccgag gaagaggacg ggaacggtgt tacgattgcc 60[3420] tgcgtttagg aggtggctgc gttgtgggaa aagctatcaa ggaagaaatt gccaaaccat 120[3421] gtcttttttt ctgttttcag agtagttcac aacagatctg agtgttttaa ttaagcatgg 180[3422] aatacagaaa acaacaaaaa acttaagctt taatttcatc tggaattcca cagttttctt 240[3423] agctccctgg acccggttga cctgttggct cttcccgctg gctgctctat cacgtggtgc 300[3424] tctccgacta ctcaccccga gtgtaaagaa ccttcggctc gcgtgcttct gagctgctgt 360[3425] ggatggcctc ggctctctgg actgtccttc cgagtaggat gtcactgaga tccctcaaat 420[3426] ggagcctcct gctgctgtca ctcctgagtt tctttgtgat gtggtacctc agccttcccc 480[3427] actacaatgt gatagaacgc gtgaactgga tgtacttcta tgagtatgag ccgatttaca 540[3428] gacaagactt tcacttcaca cttcgagagc attcaaactg ctctcatcaa aatccatttc 600[3429] tggtcattct ggtgacctcc cacccttcag atgtgaaagc caggcaggcc attagagtta 660[3430] cttggggtga aaaaaagtct tggtggggat atgaggttct tacatttttc ttattaggcc 720[3431] aagaggctga aaaggaagac aaaatgttgg cattgtcctt agaggatgaa caccttcttt 780[3432] atggtgacat aatccgacaa gattttttag acacatataa taacctgacc ttgaaaacca 840[3433] ttatggcatt caggtgggta actgagtttt gccccaatgc caagtacgta atgaagacag 900[3434] acactgatgt tttcatcaat actggcaatt tagtgaagta tcttttaaac ctaaaccact 960[3435] cagagaagtt tttcacaggt tatcctctaa ttgataatta ttcctataga ggattttacc 1020[3436] aaaaaaccca tatttcttac caggagtatc ctttcaaggt gttccctcca tactgcagtg 1080[3437] ggttgggtta tataatgtcc agagatttgg tgccaaggat ctatgaaatg atgggtcacg 1140[3438] taaaacccat caagtttgaa gatgtttatg tcgggatctg tttgaattta ttaaaagtga 1200[3439] acattcatat tccagaagac acaaatcttt tctttctata tagaatccat ttggatgtct 1260[3440] gtcaactgag acgtgtgatt gcagcccatg gcttttcttc caaggagatc atcacttttt 1320[3441] ggcaggtcat gctaaggaac accacatgcc attattaa 1358[3442] <210>78

[3443] <211>1246

[3444] <212>DNA

[3445] <213>人

[3446] <400>78

[3447] ggaaaggcct tggaaagcag tcgttgcgcc agacagccca gggaagagcg gcagcctgag 60[3448] gacctagggc cacctgctgt tccctgggat tcatgtcctt ctggggagga gggaggaccc 120[3449] aggacaatgg ctgctgttca tgatctggag atggagagca tgaatctgaa tatggggaga 180[3450] gagatgaaag aagagctgga ggaagaggag aaaatgagag aggatggggg aggtaaagat 240[3451] cgggccaaga gtaaaaaggt ccacaggatt gtctcaaaat ggatgctgcc cgaaaagtcc 300[3452] cgaggaacat acttggagag agctaactgc ttcccgcctc ccgtgttcat catctccatc 360[3453] agcctggccg agctggcagt gtttatttac tatgctgtgt ggaagcctca gaaacagtgg 420[3454] atcacgttgg acacaggcat cttggagagt ccctttatct acagtcctga gaagagggag 480[3455] gaagcctgga ggtttatctc atacatgctg gtacatgctg gagttcagca catcttgggg 540[3456] aatctttgta tgcagcttgt tttgggtatt cccttggaaa tggtccacaa aggcctccgt 600[3457] gtggggctgg tgtacctggc aggagtgatt gcagggtccc ttgccagctc catctttgac 660[3458] ccactcagat atcttgtggg agcttcagga ggagtctatg ctctgatggg aggctatttt 720[3459] atgaatgttc tggtgaattt tcaagaaatg attcctgcct ttggaatttt cagactgctg 780[3460] atcatcatcc tgataattgt gttggacatg ggatttgctc tctatagaag gttctttgtt 840[3461] cctgaagatg ggtctccggt gtcttttgca gctcacattg caggtggatt tgctggaatg 900[3462] tccattggct acacggtgtt tagctgcttt gataaagcac tgctgaaaga tccaaggttt 960[3463] tggatagcaa ttgctgcata tttagcttgt gtcttatttg ctgtgttttt caacattttc 1020[3464] ctatctccag caaactgacc tgcccctatt gtaagtcaat taataaaaag agccatctgg 1080[3465] aggaaataaa aaaaaaagga agactctatg aagaaacaga gaagtctcag aaaaggctaa 1140[3466] caattttata tagaggacaa aacagcatta aactcatcag ttgcaaagat tgcctataaa 1200[3467] aggaccttag gatttaagga aggggcttct taatgtagaa agggaa 1246[3468] <210>79

[3469] <211>704

[3470] <212>DNA

[3471] <213>人

[3472] <220>

[3473] <221>misc_feature

[3474] <222>(23)..(23)

[3475] <223>N EQUALS ANY KIND BASE

[3476] <400>79

[3477] tttttttttt tttttttcag tantcagaat aatatatttt acttcttata atgtaaaaaa 60[3478] tataatcgtt tgagtggttt tcagcatgat ctgttaattt tgaatacaga gaatgaacaa 120[3479] agcaggtaaa tatatgtata tgctgaataa tgtaattcca tatacaattc acagttagat 180[3480] gcacttaatt gtggaaaata aaggaagaca ataacatcaa gatctttttc caaaacacgg 240[3481] taaaaataac gttcacatgc attaaacatt tcaagccatc tcagtatatg tctttcttga 300[3482] gtaagtagtg aaccaatgga ccagtggtta ttgttggaga aaacaattag gcaactcatc 360[3483] aatgcgctat ttatacaatc ttagtgacta tttaccactt cacctaagta gactttccca 420[3484] ctcatttgaa gctattgcta tctataaata aatggcaaca ggaaatgttt cacaagggcc 480[3485] tttgatttcc aaaactctca aattccacag caaagactca atttaaggca attatttatg 540[3486] cactgaatat ttgaatgaag atgtattatt ttccttaagt gaaaaaagct gatactattt 600[3487] tgtaatgata aaatttgtat accatagtag aaaatgattt gcaattatgt gttaggactt 660[3488] ttcatattcc atattgaaac atagtgattc tgtagctggg atca 704[3489] <210>80

[3490] <211>1605

[3491] <212>DNA

[3492] <213>人

[3493] <400>80

[3494] atgggctgtg tgcaatgtaa ggataaagaa gcaacaaaac tgacggagga gagggacggc 60[3495] agcctgaacc agagctctgg gtaccgctat ggcacagacc ccacccctca gcactacccc 120[3496] agcttcggtg tgacctccat ccccaactac aacaacttcc acgcagccgg gggccaagga 180[3497] ctcaccgtct ttggaggtgt gaactcttcg tctcatacgg ggaccttgcg tacgagagga 240[3498] ggaacaggag tgacactctt tgtggccctt tatgactatg aagcacggac agaagatgac 300[3499] ctgagttttc acaaaggaga aaaatttcaa atattgaaca gctcggaagg agattggtgg 360[3500] gaagcccgct ccttgacaac tggagagaca ggttacattc ccagcaatta tgtggctcca 420[3501] gttgactcta tccaggcaga agagtggtac tttggaaaac ttggccgaaa agatgctgag 480[3502] cgacagctat tgtcctttgg aaacccaaga ggtacctttc ttatccgcga gagtgaaacc 540[3503] accaaaggtg cctattcact ttctatccgt gattgggatg atatgaaagg agaccatgtc 600[3504] aaacattata aaattcgcaa acttgacaat ggtggatact acattaccac ccgggcccag 660[3505] tttgaaacac ttcagcagct tgtacaacat tactcagaga aagctgacgg tttgtgtttt 720[3506] aacttaactg tgattgcatc gagttgtacc ccacaaactt ctggattggc taaagatgct 780[3507] tgggaagttg cacgtcgttc gttgtgtctg gagaagaagc tgggtcaggg gtgtttcgct 840[3508] gaagtgtggc ttggtacctg gaatggaaac acaaaagtag ccataaagac tcttaaacca 900[3509] ggcacaatgt cccccgaatc attccttgag gaagcgcaga tcatgaagaa gctgaagcac 960[3510] gacaagctgg tccagctcta tgcagtggtg tctgaggagc ccatctacat cgtcaccgag 1020[3511] tatatgaaca aaggaagttt actggatttc ttaaaagatg gagaaggaag agctctgaaa 1080[3512] ttaccaaatc ttgtggacat ggcagcacag gtggctgcag gaatggctta catcgagcgc 1140[3513] atgaattata tccatagaga tctgcgatca gcaaacattc tagtggggaa tggactcata 1200[3514] tgcaagattg ctgacttcgg attggcccga ttgatagaag acaatgagta cacagcaaga 1260[3515] caaggtgcaa agttccccat caagtggacg gcccccgagc gagccctgta cgggaggttc 1320[3516] acaatcaagt ctgacgtgtg gtcttttgga atcttactca cagagctggt caccaaagga 1380[3517] agagtgccat acccaggcat gaacaaccgg gaggtgctgg agcaggtgga gcgaggctac 1440[3518] aggatgccct gcccgcagga ctgccccatc tctctgcatg agctcatgat ccactgctgg 1500[3519] aaaaaggacc ctgaagaacg ccccactttt gagtacttgc agagcttcct ggaagactac 1560[3520] tttaccgcga cagagcccca gtaccaacct ggtgaaaacc tgtaa 1605[3521] <210>81

[3522] <211>1717

[3523] <212>DNA

[3524] <213>人

[3525] <400>81

[3526] ccggggacgg ctgctggagc ggcgcccgcc gcggctcagc gcattcccgc tctccgcttc 60[3527] cctctccgct gcgtccccgc gcgaagatgg caaccgaggg gctgcacgag aacgagacgc 120[3528] tggcgtcgct gaagagcgag gccgagagcc tcaagggcaa gctggaggag gagcgagcca 180[3529] agctgcacga tgtggagctg caccaggtgg cggagcgggt ggaggccctg gggcagtttg 240[3530] tcatgaagac cagaaggacc ctcaaaggcc acgggaacaa agtcctgtgc atggactggt 300[3531] gcaaagataa gaggaggatc gtgagctcgt cacaggatgg gaaggtgatc gtgtgggatt 360[3532] ccttcaccac aaacaaggag cacgcggtca ccatgccctg cacgtgggtg atggcatgtg 420[3533] cttatgcccc atcgggatgt gccattgctt gtggtggttt ggataataag tgttctgtgt 480[3534] accccttgac gtttgacaaa aatgaaaaca tggctgccaa aaagaagtct gttgctatgc 540[3535] acaccaacta cctgtcggcc tgcagcttca ccaactctga catgcagatc ctgacagcga 600[3536] gcggcgatgg cacatgtgcc ctgtgggacg tggagagcgg gcagctgctg cagagcttcc 660[3537] acggacatgg ggctgacgtc ctctgcttgg acctggcccc ctcagaaact ggaaacacct 720[3538] tcgtgtctgg gggatgtgac aagaaagcca tggtgtggga catgcgctcc ggccagtgcg 780[3539] tgcaggcctt tgaaacacat gaatctgaca tcaacagtgt ccggtactac cccagtggag 840[3540] atgcctttgc ttcagggtca gatgacgcta cgtgtcgcct ctatgacctg cgggcagata 900[3541] gggaggttgc catctattcc aaagaaagca tcatatttgg agcatccagc gtggacttct 960[3542] ccctcagtgg tcgcctgctg tttgctggat acaatgatta cactatcaac gtctgggatg 1020[3543] ttctcaaagg gtcccgggtc tccatcctgt ttggacatga aaaccgcgtt agcactctac 1080[3544] gagtttcccc cgatgggact gctttctgct ctggatcatg ggatcatacc ctcagagtct 1140[3545] gggcctaatc atcttctgac agtgcactca tgtatacctg agaatttgaa atcttcacat 1200[3546] gtaaatagat attacttcta gaggagctta gagtttattg cagtgtagct taggggagca 1260[3547] acccatggct cacaggtcac taagcgtctc caatatgact attaaaactg tcacctctgg 1320[3548] aaatacacta gtgtgagcct tcagcactgc gagaatacct tcaagtacag tatttttctt 1380[3549] ttggaacact ttttaaaatg tatctgtttt taaggttatt ctaaattata gtagcctcaa 1440[3550] ctcattctgt caccagtaga attcagcagt taatatattc catattattt ctttgaatca 1500[3551] attcattttc agagcacttt aaagtctgat atttctcgat gtgcactgtg atgcctggaa 1560[3552] ccttcctctg gaagtgctga ttttatggac tgaggactgg tgactggtct gtgatagaag 1620[3553] caaattccaa ttccaaatgt aattagacaa aaatcatttt tttagaatgt gtttttattg 1680[3554] taaaagtatc tttttcagca aaaaaaaaaa aaaaaaa 1717[3555] <210>82

[3556] <211>691

[3557] <212>DNA

[3558] <213>人

[3559] <220>

[3560] <221>misc_feature

[3561] <222>(281)..(281)

[3562] <223>N EQUALS ANY KIND BASE

[3563] <220>

[3564] <221>misc_feature

[3565] <222>(345)..(345)

[3566] <223>N EQUALS ANY KIND BASE

[3567] <220>

[3568] <221>misc_feature

[3569] <222>(358)..(358)

[3570] <223>N EQUALS ANY KIND BASE

[3571] <220>

[3572] <221>misc_feature

[3573] <222>(443)..(443)

[3574] <223>N EQUALS ANY KIND BASE

[3575] <220>

[3576] <221>misc_feature

[3577] <222>(478)..(478)

[3578] <223>N EQUALS ANY KIND BASE

[3579] <400>82

[3580] tttttttttt tttttagaac cttagcactt taatagaatt agagactttg gaatttcagg 60[3581] tccttagaac caaagactca cagcatcttt gaaacctaga acctttgaat ctagactctt 120[3582] taaaccttgg actctagagt cttggaatgt taacacctgg gagggcttca gatattgcaa 180[3583] tccaacccct tccttttaca gatggtgatg ctactgcttt caaggtgatg ctactgcaca 240[3584] gagaagggga gggacctgtc tgggatggag gtgggatagg ntagagacag ggctgcaagt 300[3585] ggggataagg cgtggtggga aagtgggaag ggggagtttc cccantggca gtgcttanct 360[3586] tggatcctga gagggagtac caggtggagg gttgtctcag gcaccatcct cctgccctgg 420[3587] ggctgctggg gagcccctat cancaggctg agcggggcta ggggttgtgg aagggcanag 480[3588] gacatagcgt tcagcaggat ggacctcaac cgcagtgagg cagctacagg aatccttagg 540[3589] gtctggctgg gtttgggggg tcagctcctt cttgagcttc cagggggtca aggtaacctc 600[3590] caccttattc atggtgacat agagggattc gtcggcttct gggcagggaa gcagggcttt 660[3591] agtggtgtct tcaaaacttc cccgagctct g 691[3592] <210>83

[3593] <211>1284

[3594] <212>DNA

[3595] <213>人

[3596] <400>83

[3597] ggcctgtaca ttttcaagga attcttgaga ggttcttgga gagattctgg gagccaaaca 60[3598] ctccattggg atcctagctg ttttagagaa caacttgtaa tggagccttc atctcttgag 120[3599] ctgccggctg acacagtgca gcgcattgcg gctgaactca aatgccaccc aacggatgag 180[3600] agggtggctc tccacctaga tgaggaagat aagctgaggc acttcaggga gtgcttttat 240[3601] attcccaaaa tacaggatct gcctccagtt gatttatcat tagtgaataa agatgaaaat 300[3602] gccatctatt tcttgggaaa ttctcttggc cttcaaccaa aaatggttaa aacatatctt 360[3603] gaagaagaac tagataagtg ggccaaaata gcagcctatg gtcatgaagt ggggaagcgt 420[3604] ccttggatta caggagatga gagtattgta ggccttatga aggacattgt aggagccaat 480[3605] gagaaagaaa tagccctaat gaatgctttg actgtaaatt tacatcttct aatgttatca 540[3606] ttttttaagc ctacgccaaa acgatataaa attcttctag aagccaaagc cttcccttct 600[3607] gatcattatg ctattgagtc acaactacaa cttcacggac ttaacattga agaaagtatg 660[3608] cggatgataa agccaagaga gggggaagaa accttaagaa tagaggatat ccttgaagta 720[3609] attgagaagg aaggagactc aattgcagtg atcctgttca gtggggtgca tttttacact 780[3610] ggacagcact ttaatattcc tgccatcaca aaagctggac aagcgaaggg ttgttatgtt 840[3611] ggctttgatc tagcacatgc agttggaaat gttgaactct acttacatga ctggggagtt 900[3612] gattttgcct gctggtgttc ctacaagtat ttaaatgcag gagcaggagg aattgctggt 960[3613] gccttcattc atgaaaagca tgcccatacg attaaacctg cgagatcgga gttctttaat 1020[3614] taggaatgga atgcaacaga tttggacaag tcaaggacaa gagctttaga gagaccaaag 1080[3615] agtttttcac tgttaaagtg tccagtatgt agccgagaac catatggaga acatcaaata 1140[3616] cagtggaaca aatgtaactg ctattgatgt cacactttgt gaagtagtct ttgttgctta 1200[3617] aaaagggtga catctagtgg ctaaacatgt tatttcaaat aaataatatc gaaataaaaa 1260[3618] aaaaaaaaaa aaaaaaaaaa aaaa 1284[3619] <210>84

[3620] <211>566

[3621] <212>DNA

[3622] <213>人

[3623] <400>84

[3624] ttttgggatg cttcactttc tttattgccc atccagggga cagccaagcc agctccatct 60[3625] gcattctggc tgcagcgtgt acattagggg actcaggggc cacagtgtgg gaccgtgcac 120[3626] actggcaagg cactggcgga tgctggcagg ccagtggaca tggatagatg agaatgacaa 180[3627] ctcacagatg tcctagcttc cgctggccca gctgccagcc actggccatc acccttttgc 240[3628] ccagcatgtg tgcattgtca cccaaaacat cttgaaactt gccattagtg aggcattcaa 300[3629] caaagaagta agctaagtga gtaggaaaca gtgtttcctg gaatataccg cactctgcct 360[3630] gaaataggaa aactatgttt gccgggaagc agcagcagca ggaaagaagt tataccaaaa 420[3631] acgacttgta caccacagac attataaccc tttcctcaaa gaaacagtca tgttctgttg 480[3632] ggtattatgg acaggtctct ggaaatttat ctaataaaga ccaacaaact tccccagcag 540[3633] tgcctctgag taccgtgtga attctg 566[3634] <210>85

[3635] <211>813

[3636] <212>DNA

[3637] <213>人

[3638] <220>

[3639] <221>misc_feature

[3640] <222>(688)..(688)

[3641] <223>N EQUALS ANY KIND BASE

[3642] <400>85

[3643] tttttttttt tttttttttt tttttttttt ttaaacaaac aaaaaagaag tttactaaat 60[3644] ttaaacactg acatcctggg aagatgccag tctttacagg cgtttgtaaa agtaaactgg 120[3645] ggggagtatg ttacactaat acaaagtttt acaaatgaat acaagtgaaa tatttaaatt 180[3646] acaatgaaat agaggaagat tggggctttg tcctgggttg gtttttttag cagtcatatt 240[3647] gctgttgggg agagcagcaa aagccacata tgcctccaag cactccattt attacttgaa 300[3648] taagacacaa gatgaattca attccaccaa gagccaagag gatagaaaac agagatacat 360[3649] tccattccac aatgtgcttg ggttcagtgc actcggacca tgtggaggta tccaaaaggg 420[3650] tcttgccctt ggggcttgga aaaggggtat ttccactggc cgagggaatc aagacatagt 480[3651] ggtccttctg ctaagccaag ggctgccaca atgacacagt agccagatcc tgcaattcca 540[3652] atgagagcag ccaatacaga agaaagcatc gcacatcgtt tgccacagtt ttcatggcca 600[3653] cagcagccac agcagtcatc ctgttccagc ccaatgaaga caaatgctgg caggagcatc 660[3654] agcaggccac cttctacgat gccagaanaa gaacacacga aagcgggttg aggggttttg 720[3655] ggaggcattc tttgtttccc ccttggggaa ataaaagcaa attttaaccc gggatgcccc 780[3656] aggaggcggg ccccaaccaa aaaaatgtcg gat 813[3657] <210>86

[3658] <211>2328

[3659] <212>DNA

[3660] <213>人

[3661] <400>86

[3662] gccagccgag cggccagcca gtgcggggct ggccatgtaa ggcccacagg cggtcctgcc 60[3663] cgcccggtgc cctgcggaga gcctcgtgca gccctgggca ccgcccctgc cctgccctga 120[3664] ccccttggcc ttgaaatgct gtcatcggag gagccgtccc gctcgggaca aggccagcat 180[3665] ggacaaagct agagctgggg caagcaagga gccttcctgt cctcgaggcc gtgggaagag 240[3666] aagcacgccc agggggccac tcctgagagc ctctctgtcc accaggcctc tgcagagggg 300[3667] tcaccatggc tctggcccga ggcagccggc agctgggggc cctggtgtgg ggcgcctgcc 360[3668] tgtgcgtgct ggtgcacggg cagcaggcgc agcccgggca gggctcggac cccgcccgct 420[3669] ggcggcagct gatccagtgg gagaacaacg ggcaggtgta cagcttgctc aactcgggct 480[3670] cagagtacgt gccggccgga cctcagcgct ccgagagtag ctcccgggtg ctgctggccg 540[3671] gcgcgcccca ggcccagcag cggcgcagcc acgggagccc ccggcgtcgg caggcgccgt 600[3672] ccctgcccct gccggggcgc gtgggctcgg acaccgtgcg cggccaggcg cggcacccat 660[3673] tcggctttgg ccaggtgccc gacaactggc gcgaggtggc cgtcggggac agcacgggca 720[3674] tggccctggc ccgcacctcc gtctcccagc aacggcacgg gggctccgcc tcctcggtct 780[3675] cggcttcggc cttcgccagc acctaccgcc agcagccctc ctacccgcag cagttcccct 840[3676] acccgcaggc gcccttcgtc agccagtacg agaactacga ccccgcgtcg cggacctacg 900[3677] accagggttt cgtgtactac cggcccgcgg gcggcggcgt gggcgcgggg gcggcggccg 960[3678] tggcctcggc gggggtcatc tacccctacc agccccgggc gcgctacgag gagtacggcg 1020[3679] gcggcgaaga gctgcccgag tacccgcctc agggcttcta cccggccccc gagaggccct 1080[3680] acgtgccgcc gccgccgccg ccccccgacg gcctggaccg ccgctactcg cacagtctgt 1140[3681] acagcgaggg cacccccggc ttcgagcagg cctaccctga ccccggtccc gaggcggcgc 1200[3682] aggcccatgg cggagaccca cgcctgggct ggtacccgcc ctacgccaac ccgccgcccg 1260[3683] aggcgtacgg gccgccgcgc gcgctggagc cgccctacct gccggtgcgc agctccgaca 1320[3684] cgcccccgcc gggtggggag cggaacggcg cgcagcaggg ccgcctcagc gtaggcagcg 1380[3685] tgtaccggcc caaccagaac ggccgcggtc tccctgactt ggtcccagac cccaactatg 1440[3686] tgcaagcatc cacttatgtg cagagagccc acctgtactc cctgcgctgt gctgcggagg 1500[3687] agaagtgtct ggccagcaca gcctatgccc ctgaggccac cgactacgat gtgcgggtgc 1560[3688] tactgcgctt cccccagcgc gtgaagaacc agggcacagc agacttcctc cccaaccggc 1620[3689] cacggcacac ctgggagtgg cacagctgcc accagcatta ccacagcatg gacgagttca 1680[3690] gccactacga cctactggat gcagccacag gcaagaaggt ggccgagggc cacaaggcca 1740[3691] gtttctgcct ggaggacagc acctgtgact tcggcaacct caagcgctat gcatgcacct 1800[3692] ctcataccca gggcctgagc ccaggctgct atgacaccta caatgcggac atcgactgcc 1860[3693] agtggatcga cataaccgac gtgcagcctg ggaactacat cctcaaggtg cacgtgaacc 1920[3694] caaagtatat tgttttggag tctgacttca ccaacaacgt ggtgagatgc aacattcact 1980[3695] acacaggtcg ctacgtttct gcaacaaact gcaaaattgt ccaatcctga tctccgggag 2040[3696] ggacagatgg ccaatctctc cccttccaaa gcaggccctg ctccccgggc agcctcccgc 2100[3697] cgaggggccc agcccccaac ccacaggcag ggaggggcat ccctccctgc cggcctcagg 2160[3698] gagcgaacgt ggatgaaaac cacagggatt ccggatgcca gaccccattt tatacttcac 2220[3699] ttttctctac agtgttgttt tgttgttgtt ggtttttatt ttttatactt tggccatacc 2280[3700] acagagctag attgcccagg tctgggctga ataaaacaag gtttttct 2328[3701] <210>87

[3702] <211>544

[3703] <212>DNA

[3704] <213>人

[3705] <400>87

[3706] aggcttttag aaaatttatt atgaattccg agaagtctgc tcatcatata cctcccccag 60[3707] ccccaaataa aacaaacaac atgtttgtac ataaagcctg gatttacttg gtacaaaatt 120[3708] tgagtctttg aaaaaaatag ttaatggaaa atctcaataa aaattcattt tgaaagtaac 180[3709] cagtactgtt cagaaataag gaagtcatgt tacttgagaa gtcacacagt tttattacag 240[3710] aactatgtgt atatattttg ggtttaaaac ttgccaatag ctgtttgaaa ggatagctca 300[3711] taatttattc aaatagatat tttattaatc aaatgttttt ggtttatcaa cataaccaaa 360[3712] tgtataaaaa atgtttttaa atacaagaca taactataaa gtcatgaggc tgattgacct 420[3713] tttaaactaa cataataaaa tctatatggt caaaatgagt ggtgatgctt taaggtaatg 480[3714] attatgcgtc ccatctaagg atgctgcaat ggcctagggc agttttgaaa tgtctctttg 540[3715] caac 544[3716] <210>88

[3717] <211>5189

[3718] <212>DNA

[3719] <213>人

[3720] <400>88

[3721] cttgcgaggt gagcatttcc aaggctgtgt gctcgtgggg tggggggaca cacgatgacc 60[3722] ttctcctcct caggaagacc taagagggaa gagcaaaccc cagcgagatc ccccctgtgc 120[3723] tgatgatttt cagggacttg ttggcaactc agcgagggtt gccatagctt ttttatgtag 180[3724] ggtgaccaga accggctgaa actggtttga ggcagatcag ctcctgaaca caatgcagtc 240[3725] actgagctac tacagtagga tagcagcttc ctcccttcat ggcagccaaa agcagaggag 300[3726] cttgcaggaa ggtaccatcc ctacacagta tgtgaatgca cacttagaca ccacacagca 360[3727] ctggtacgtg actaatggag ccctaaaaga ttctgggtag agaagatgga aaaaaaggtg 420[3728] caggtttgca gggtctgaga ttacttgggc ttttcctgcc tttttctttt gcttaaggga 480[3729] tggacaagga gctgagattt atgaccctta ttagagaaaa aaatgtgcct tgctagggtg 540[3730] gggacacttg gttgatgcag tctctctctc tctttctcgg tgtttataac aaaacaaaac 600[3731] caaaatgaac tgaggggttt gtaatggtag tttgtttgtt gctggagaat gctactttgc 660[3732] atgctttttt tctcttgcag ggtatgttct gtcttgtgct ttttctttta gaagctacta 720[3733] aagggtgttg gggatgcttc tgactattat gaaggccaaa aggcctgttg actggggctg 780[3734] cttttaaccc tttcctattt gctgagaatg cagccgtgtg acagtaactg aacattggtc 840[3735] taaagtcttt ccaaaaggtc aaggttcaca agaacatctg ctcaaattaa tgaccatggg 900[3736] ggatatgaag accccagact ttgatgacct cctggcagca tttgacatcc cagatatggt 960[3737] cgatcctaaa gcagctattg agtctggaca cgatgaccat gaaagccaca tgaagcagaa 1020[3738] tgctcacgga gaggatgact cccacgcacc atcatcttct gatgtgggtg tcagcgttat 1080[3739] cgtcaagaat gttcggaaca ttgactcttc cgagggcggg gagaaagacg gccacaaccc 1140[3740] cactggcaat ggcttacata atgggtttct cacagcatcc tcccttgaca gttacagtaa 1200[3741] agatggagca aagtccttga aaggagatgt gcctgcctct gaggtgacac tgaaagactc 1260[3742] gacattcagc cagtttagcc cgatctccag tgctgaagag tttgatgacg acgagaagat 1320[3743] tgaggtggat gacccccctg acaaggagga catgcgatca agcttcaggt cgaatgtgtt 1380[3744] gacggggtcg gctccccagc aggactacga taagctgaag gcactcggag gggaaaactc 1440[3745] cagcaaaact ggactctcta cgtcaggcaa tgtggagaaa aacaaagctg ttaagagaga 1500[3746] aacagaagcc agttctataa acctgagtgt ttatgaacct tttaaagtca gaaaagcaga 1560[3747] ggataaattg aaggaaagct ctgacaaggt gctggaaaac agagtcctag atgggaagct 1620[3748] gagctccgag aagaatgaca ccagcctccc cagcgttgcg ccatcaaaga caaagtcgtc 1680[3749] ctccaagctc tcgtcctgca tcgctgccat cgcggctctc agcgctaaaa aggcggcttc 1740[3750] agactcctgc aaagaaccag tggccaattc gagggaatcc tccccgttac caaaagaagt 1800[3751] aaatgacagt ccgagagccg ctgacaagtc tcctgaatcc cagaatctca tcgacgggac 1860[3752] caaaaaacca tccctgaagc aaccggatag tcccagaagc atctcaagtg agaacagcag 1920[3753] caaaggatcc ccgtcctctc ccgcagggtc cacaccagca atccccaaag tccgcataaa 1980[3754] aaccattaag acatcttctg gggaaatcaa gagaacagtg accagggtat tgccagaagt 2040[3755] ggatcttgac tctggaaaga aaccttccga gcagacagcg tccgtgatgg cctctgtgac 2100[3756] atcccttctg tcgtctccag catcagccgc cgtcctttcc tctcccccca gggcgcctct 2160[3757] ccagtctgcg gtcgtgacca atgcagtttc ccctgcagag ctcaccccca aacaggtcac 2220[3758] aatcaagcct gtggctactg ctttcctccc agtgtctgct gtgaagacgg caggatccca 2280[3759] agtcattaat ttgaagctcg ctaacaacac cacggtgaaa gccacggtca tatctgctgc 2340[3760] ctctgtccag agtgccagca gcgccatcat taaagctgcc aacgccatcc agcagcaaac 2400[3761] tgtcgtggtg ccggcatcca gcctggccaa tgccaaactc gtgccaaaga ctgtgcacct 2460[3762] tgccaacctt aaccttttgc ctcagggtgc ccaggccacc tctgaactcc gccaagtgct 2520[3763] aaccaaacct cagcaacaaa taaagcaggc aataatcaat gcagcagcct cgcaaccccc 2580[3764] caaaaaggtg tctcgagtcc aggtggtgtc gtccttgcag agttctgtgg tggaagcttt 2640[3765] caacaaggtg ctgagcagtg tcaatccagt ccctgtttac atcccaaacc tcagtcctcc 2700[3766] cgccaatgca gggatcacgt taccgacgcg tgggtacaag tgcttggagt gtggggactc 2760[3767] ctttgcactt gaaaagagtc tgacccagca ctacgacaga cggagcgtgc gcatcgaagt 2820[3768] aacgtgcaac cattgtacaa agaacctcgt tttttacaac aaatgcagcc tcctttccca 2880[3769] tgcccgtggg cataaggaga aaggggtggt aatgcaatgc tcccacttaa ttttaaagcc 2940[3770] agtcccagca gatcaaatga tagtttctcc gtcaagcaat acttccactt caacttccac 3000[3771] tcttcagagc cctgtgggag ctggcacaca cactgtcaca aaaattcagt ctggcataac 3060[3772] tgggacagtc atatcggctc cttcaagcac tcccatcacc ccagccatgc ccctagatga 3120[3773] agacccctcc aaactgtgta gacatagtct aaaatgtttg gagtgtaatg aagtcttcca 3180[3774] ggacgagaca tcactggcta cacatttcca gcaggctgca gatacgagtg gacaaaagac 3240[3775] ttgcactatc tgccagatgc tgcttcctaa ccagtgcagt tatgcatcac accagagaat 3300[3776] ccatcagcac aaatctccct acacctgccc tgagtgtggg gccatctgca ggtcggtgca 3360[3777] cttccagacc cacgtcacca agaactgtct gcactacacg aggagagttg gttttcgatg 3420[3778] tgtgcattgc aatgttgtgt actctgatgt ggctgctctg aagtctcaca ttcaaggttc 3480[3779] tcactgtgaa gtcttctaca agtgtcctat ttgtccaatg gcgtttaagt ctgccccaag 3540[3780] cacacattcc cacgcctaca cacagcatcc tggcatcaag ataggagaac caaaaataat 3600[3781] atataagtgt tccatgtgcg acactgtgtt caccctgcaa accttgctgt atcgccactt 3660[3782] tgaccaacac attgaaaacc agaaggtgtc tgttttcaag tgtccagact gttctctttt 3720[3783] atatgcacag aagcaactta tgatggacca tatcaagtct atgcatggaa cattgaaaag 3780[3784] tattgaaggg cctccaaact tgggtataaa cttgcctttg agcattaagc ctgcaactca 3840[3785] aaattcagca aatcagaaca aagaggacac caaatccatg aatgggaaag agaaattgga 3900[3786] aaagaaatct ccatctcctg tgaaaaaatc aatggaaacc aagaaagtgg ccagtcctgg 3960[3787] gtggacgtgt tgggagtgtg actgcctgtt catgcagaga gatgtgtaca tatcccacgt 4020[3788] gaggaaggag cacgggaagc aaatgaagaa acacccctgc cgccagtgtg acaagtcttt 4080[3789] cagctcgtcc cacagcctgt gccggcacaa ccggatcaag cacaaaggca tcaggaaagt 4140[3790] gtacgcctgc tcgcactgcc cagactccag acgtaccttt accaaacgtt tgatgctgga 4200[3791] gaagcacgtc cagctgatgc atggcatcaa ggaccctgac ctgaaagaaa tgacagatgc 4260[3792] caccaatgag gaggaaacag aaataaaaga agacactaag gtccccagtc ccaagcggaa 4320[3793] gttggaagaa ccagttctgg agttcaggcc tccccgagga gcaatcactc aaccactgaa 4380[3794] aaagctgaaa atcaatgttt ttaaggttca caagtgtgcc gtgtgtggct tcaccaccga 4440[3795] aaacctgctg caattccacg aacacatccc tcagcacaaa tcggatggtt cttcctacca 4500[3796] gtgccgggag tgtggcctct gctacacgtc tcacgtctct ctgtccaggc acctcttcat 4560[3797] cgtacacaag ttaaaggaac ctcagccagt gtccaagcaa aatggggctg gggaagataa 4620[3798] ccaacaggag aacaaaccca gccacgagga tgaatcccct gatggcgccg tgtcagacag 4680[3799] aaagtgcaaa gtgtgcgcaa aaacttttga aactgaagct gccttaaata ctcacatgcg 4740[3800] gacacacggc atggccttca tcaaatccaa aaggatgagc tcagccgaga aatagccaca 4800[3801] gatgctccat gaggaaaatc cctgtccaca ttggaataaa aaagacattt ttgttacaaa 4860[3802] gtttgcagta taatagagtt aacagtactg tctaggctgt tgcaatatat tctctttcaa 4920[3803] tgtaccttcc ttcacctcgt cgtatatatc ctcgataagt attaaaacag tatttgagtt 4980[3804] taaaagagtt tgtatatatt taaatgaata actttttata ctctttgtta catgtttgta 5040[3805] tcagtattta gtggaaaacc atttgagttg ttttgggtta gaatttttct ttttgtactg 5100[3806] tttctttaaa acagagttct tagtaacagg ggcagttcct gaattcaaat aaaccatttt 5160[3807] gtatgtttgg aaaaaaaaaa aaaaaaaaa 5189[3808] <210>89

[3809] <211>1061

[3810] <212>DNA

[3811] <213>人

[3812] <400>89

[3813] ctctgttttc tcaaagctga agtcggctag gtttgcaaag ctgtgggctg agcactcagg 60[3814] caatcacact ctcagaaact gcggcggctc tggactgcag cctcccaagg ctccatgcca 120[3815] gacaaagcat gcgtgtcaca cttgctacaa tagcctggat ggtttctttt gtctccaatt 180[3816] attcacacac agcaaatatt ttgccagata tcgaaaatga agatttcatc aaagactgcg 240[3817] ttcgaatcca taacaagttc cgatcagagg tgaaaccaac agccagtgat atgctataca 300[3818] tgacttggga cccagcacta gcccaaattg caaaagcatg ggccagcaat tgccagtttt 360[3819] cacataatac acggctgaag ccaccccaca agctgcaccc aaacttcact tcactgggag 420[3820] agaacatctg gactgggtct gtgcccattt tttctgtgtc ttccgccatc acaaactggt 480[3821] atgacgaaat ccaggactat gacttcaaga ctcggatatg caaaaaagtc tgtggccact 540[3822] acactcaggt tgtttgggca gatagttaca aagttggctg cgcagttcaa ttttgcccta 600[3823] aagtttctgg ctttgacgct ctttccaatg gagcacattt tatatgcaac tacggaccag 660[3824] gagggaatta cccaacttgg ccatataaga gaggagccac ctgcagtgcc tgccccaata 720[3825] atgacaagtg tttggacaat ctctgtgtta accgacagcg agaccaagtg aaacgttact 780[3826] actctgttgt atatccaggc tggcccatat atccacgtaa cagatacact tctctctttc 840[3827] tcattgttaa ttcagtaatt ctaatactgt ctgttataat taccattttg gtacagctca 900[3828] agtaccctaa tttagttctt ttggactaat acaattcagg aaagaaaaaa cccaaaaacc 960[3829] aacctcattc acatatggct tttttttaac caataacaat taggtgtact tctattttaa 1020[3830] aacatttcag aaaaaaatat atgttatagc aatactctta c 1061[3831] <210>90

[3832] <211>1453

[3833] <212>DNA

[3834] <213>人

[3835] <400>90

[3836] agcgcgagtg ccagagccca gccggcgcgg agcgggagcg gtgcaggctg aggtctccga 60[3837] gcggctcgcc atggctggcc cgcagcagca gcccccttac ctgcacctgg ccgagctgac 120[3838] ggcgtcccag ttcctggaaa tatggaagca ctttgacgca gacggaaatg ggtatattga 180[3839] aggtaaagag ctagaaaact ttttccaaga gctggagaag gcaaggaaag gctctggcat 240[3840] gatgtcaaag agtgacaact ttggagaaaa gatgaaggag ttcatgcaga agtatgataa 300[3841] aaactcagat gggaaaatcg agatggcaga gctggcgcag atcctgccaa ccgaagagaa 360[3842] cttccttctg tgcttcaggc agcacgtggg ctccagcgcc gagtttatgg aggcttggcg 420[3843] gaagtacgac acagacagga gtggctacat cgaagccaat gagctcaagg gattcctgtc 480[3844] agacctgctg aagaaggcga accggccgta cgatgagccc aagctccagg aatacaccca 540[3845] aaccatacta cggatgtttg acttgaacgg ggatggcaaa ttgggcctct cagagatgtc 600[3846] ccgactcctg cctgtccagg aaaacttcct gcttaaattt cagggcatga agctgacctc 660[3847] agaggagttt aacgcgatct tcacatttta cgacaaggat agaagcggct acattgacga 720[3848] gcatgagctg gatgcccttt tgaaggatct gtacgagaaa aacaaaaagg aaatcaatat 780[3849] tcaacagctc accaactaca gaaagagcgt catgtccttg gcagaggcag ggaagctcta 840[3850] ccgcaaggac ctggagattg tgctctgcag cgagcccccc atgtaaagtg gggacggggg 900[3851] ctgcttctcc acctccccca aaccctgctt ctgctgccct gatgcgtcta cccagactca 960[3852] gagaccgtga gcgccccgcc cccaccccta cagcctgcac acacctgcct gcagagcagg 1020[3853] aaacgagaga tagaggatgg gcagctgggg ggctgtcctg agccccctgc acccacccct 1080[3854] gcccaggcag tctttgctca gtggatcaca cacatggaag gtgatggggg catgggtgga 1140[3855] gggtccctaa ttctcttcgc tgtgatgcat gagctccctc gctgtatgat ttaggcttct 1200[3856] atgtccaaca gagtggactc ttccctctcg ctcccctctg ccggtccccc atgccaccac 1260[3857] ccaccccaaa cttccaggtt ccatccacca ccttgccaat ggtgtagctg tcctctcaga 1320[3858] actcctgtgt gtggaaggca cccgcccttt ccttgccttc tttactcggc gtgctccttt 1380[3859] tctctttggg tttcttgttt accaaagaag agtttacaga caataaaatg gaaaggtcct 1440[3860] gctgtggaaa ctt 1453[3861] <210>91

[3862] <211>2223

[3863] <212>DNA

[3864] <213>人

[3865] <400>91

[3866] tcagtgtgtg cggaacgcaa gcagccgaga gcggagaggc gccgctgtag ttaactcctc 60[3867] cctgcccgcc gcgccgaccc tccccaggaa cccccaggga gccagcatga agcgagctca 120[3868] ccccgagtac agctcctcgg acagcgagct ggacgagacc atcgaggtgg agaaggagag 180[3869] tgcggacgag aatggaaact tgagttcggc tctaggttcc atgtccccaa ctacatcttc 240[3870] ccagattttg gccagaaaaa gacggagagg aataattgag aagcgccgac gagaccggat 300[3871] caataacagt ttgtctgagc tgagaaggct ggtacccagt gcttttgaga agcagggatc 360[3872] tgctaagcta gaaaaagccg agatcctgca gatgaccgtg gatcacctga aaatgctgca 420[3873] tacggcagga gggaaaggtt actttgacgc gcacgccctt gctatggact atcggagttt 480[3874] gggatttcgg gaatgcctgg cagaagttgc gcgttatctg agcatcattg aaggactaga 540[3875] tgcctctgac ccgcttcgag ttcgactggt ttcgcatctc aacaactacg cttcccagcg 600[3876] ggaagccgcg agcggcgccc acgcgggcct cggacacatt ccctggggga ccgtcttcgg 660[3877] acatcacccg cacatcgcgc acccgctgtt gctgccccag aacggccacg ggaacgcggg 720[3878] caccacggcc tcacccacgg aaccgcacca ccagggcagg ctgggctcgg cacatccgga 780[3879] ggcgcctgct ttgcgagcgc cccctagcgg cagcttcgga ccggtgctcc ctgtggtcac 840[3880] ctccgcctcc aaactgtcgc tgcctctgct ctcctcagtg gcctccctgt cggccttccc 900[3881] cttctctttc ggctccttcc acttactgtc tcccaatgca ctgagccctt cagcacccac 960[3882] gcaggctgca aaccttggca agccctatag accttggggg acggagatcg gagcttttta 1020[3883] aagaactgat gtagaatgag ggaggggaaa gtttaaaatc ccagctgggc tggactgttg 1080[3884] ccaacatcac cttaaagtcg tcagtaaaag taaaaaggaa aaaggtacac tttcagataa 1140[3885] tttttttttt aaagactaaa ggtttgttgg tttactttta tcttttttaa tgtttttttc 1200[3886] atcatgtcat gtattagcag tttttaaaaa ctagttgtta aattttgttc aagacattaa 1260[3887] attgaaatag tgagtataag ccaacacttt gtgataggtt tgtactgtgc ctaatttact 1320[3888] ttgtaaacca gaatgattcc gtttttgcct caaaatttgg ggaatcttaa catttaggta 1380[3889] tttttggtct gtttttctcc ttgtatagtt atggtctgtt tttagaatta attttccaaa 1440[3890] ccactatgct taatgttaac atgattctgt ttgttaatat tttgacagat taaggtgttg 1500[3891] tataaataat attcttttgg ggggagggga actatattga attttatatt tctgagcaaa 1560[3892] gcgttgacaa atcagatgat cagctttatc caagaaagaa gactagtaaa ttgtctgcct 1620[3893] cctatagcag aaaggtgaat gtacaaactg ttggtggcct gaatccatct gaccagctgc 1680[3894] tggtatctgc caggactggc agttctgatt tagttaggag gaccgctgat aggttaggtc 1740[3895] tcatttggag tgttggtgga aaggaaactg aaggtaattg aatagaatac gcctgcattt 1800[3896] accagcccca gcaacacaaa gaatttttaa tcacacggat ctcaaattca caaatgttaa 1860[3897] catggataag tgatcatggt gtgcgagtgg tcaattgagt agtacagtgg aaactgttaa 1920[3898] atgcataacc taattttcct gggactgcca tattttcttt taactggaaa tttttatgtg 1980[3899] agttttcctt ttggtgcatg gaactgtggt tgccaaggta tttaaaaggg ctttcctgcc 2040[3900] tccttctctt tgatttattt aatttgattt gggctataaa atatcatttt tcaggtttat 2100[3901] tcttttagca ggtgtagtta aacgacctcc actgaactgg gtttgacctc tgttgtactg 2160[3902] atgtgttgtg actaaataaa aaagaaagaa caaagtaaaa aaaaaaa aaaaaaaaaa 2220[3903] aaa 2223[3904] <210>92

[3905] <211>4712

[3906] <212>DNA

[3907] <213>人

[3908] <400>92

[3909] cccggcggtg gcggcgtctc tggccggcct tggtgcggcg agccgagcga ggcagctctg 60[3910] agccgcgcgg aaatctggca ttttttaaag tttgcgcccc acaaagagga aatattccaa 120[3911] aggtactcag gatgtaaaag gggagatctt cacagatgcc tccgtggatg gcatggcaat 180[3912] ccatccatca atgagaagac catgatttct tttaattttc tgtgtgtttc cacattcccc 240[3913] agtgagaatt cttccacctt tttttgtgcc atgggaaaaa cctgaagggc aggcagagct 300[3914] gctcccgaac ttgtgacctt ctctgaggtt gcagcggctc ttgtagaaca tgactctggg 360[3915] acatcacttc cttttgtttt ctttcggagc tgaaccaaag aatgtgcacc ctctttctct 420[3916] agtgctgtgg tgtctgctta tttttgtatt tgtgctttcc atccatcttc tgtgatcaca 480[3917] aggcattctt aaggttttct agcacgactt gcggacatcc agactcgtgg ggggcccacc 540[3918] catggctcgg taagccagca gcccagggca ctggcactac catgaggcac tgcattaatt 600[3919] gctgcataca gctgttaccc gacggcgcac acaagcagca ggtcaactgc caagggggcc 660[3920] cccatcacgg tcaccaggcg tgccccacgt gcaaaggaga aaacaaaatt ctgtttcgtg 720[3921] tggacagtaa gcagatgaac ttgcttgctg ttctcgaagt gaggactgaa gggaacgaaa 780[3922] actggggtgg gtttttgcgc ttcaaaaagg ggaagcgatg tagcctcgtt tttggactga 840[3923] taataatgac cttggtaatg gcttcttaca tcctttctgg ggcccaccaa gagcttctga 900[3924] tctcatcacc tttccattac ggaggcttcc ccagcaaccc cagcttgatg gacagcgaaa 960[3925] acccaagtga cacaaaggag catcaccacc aatcctctgt aaataatatt tcatacatga 1020[3926] aggactatcc aagcattaaa ttaattatca acagcatcac aactaggatt gagttcacga 1080[3927] ccagacagct cccagactta gaagacctta agaagcagga gttgcatatg ttttcagtca 1140[3928] tccccaacaa attccttcca aacagtaaga gcccctgttg gtacgaggag ttctcggggc 1200[3929] agaacaccac cgacccctac ctcaccaact cctacgtgct ctactccaag cgcttccgct 1260[3930] ccaccttcga cgccctgcgc aaggccttct ggggccacct ggcgcacgcg cacgggaagc 1320[3931] acttccgcct gcgctgcctg ccgcacttct acatcatagg gcagcccaag tgcgggacca 1380[3932] cagacctcta tgaccgcctg cggctgcacc ctgaggtcaa gttctccgcc atcaaggagc 1440[3933] cacactggtg gacccggaag cgctttggaa tcgtccgcct aagagatggg ctgcgagacc 1500[3934] gctatcccgt ggaagattat ctggacctct ttgacctggc cgcacaccag atccatcaag 1560[3935] gactgcaggc cagctctgca aaggagcaga gcaagatgaa tacaatcatt atcggggagg 1620[3936] ccagtgcctc cacgatgtgg gataataatg cctggacgtt cttctacgac aacagcacgg 1680[3937] atggcgagcc accgtttctg acgcaggact tcatccacgc ctttcagcca aatgccagac 1740[3938] tgattgtcat gctcagggac cctgtggaga ggttgtactc agactatctc tactttgcaa 1800[3939] gttcgaataa atccgcggac gacttccatg agaaagtgac agaagcactg cagctgtttg 1860[3940] aaaattgcat gcttgattat tcactgcgcg cctgcgtcta caacaacacc ctcaacaacg 1920[3941] ccatgcctgt gaggctccag gttgggctct atgctgtgta ccttctggac tggctcagcg 1980[3942] tttttgacaa gcaacagttt ctcattcttc gcctggaaga tcatgcatcc aacgtcaagt 2040[3943] acaccatgca caaggtcttc cagtttctga acctagggcc cttaagtgag aagcaggagg 2100[3944] ctttgatgac caagagcccc gcatccaatg cacggcgtcc cgaggaccgg aacctggggc 2160[3945] ccatgtggcc catcacacag aagattctgc gggatttcta caggcccttc aacgctaggc 2220[3946] tggcgcaggt cctcgcggat gaggcgtttg cgtggaagac gacgtgagag ctgaattgtt 2280[3947] gctgcacgtg ctgggcccgc caatgccgtc atcatcagga ttttacaaat ctctttgcgg 2340[3948] ggaactgttt cactcatggt atggaaaacc ccaggactct gccactctag gcacacatga 2400[3949] attataacca ttttggaatt tccttcgtga tgttcgagag ctcagcaatg gacccctcac 2460[3950] agagctcctc tatccgaggc cattggagac cccagtttct caagaattca gctctgctct 2520[3951] gagcgtcctg gagcttgggg atgcagccag ctggcctgca ctgggtgtgg agagaacacc 2580[3952] tagggaaggc agcctggccc tgcccgcctc cgccttctgg agagcctctg ggttctgagt 2640[3953] cagcaagcca gaggtcatgc cacaggcctg gctggaactt acacttcacg ttcccttttt 2700[3954] ttccccctag agatggggtc tcgccgtgtt gcacagactg tctgtattca atggctatct 2760[3955] tcacaggtgt gatcatacca cattcacttc tgaaacactc ttgttgcgat cgctaacctc 2820[3956] actgggacag agaaccgcag tctttcgaga atggaggctc ttcatttttt ttttctcctt 2880[3957] tactccaaac tcagccctcc agtttcttca gatgtaaacc ctgttaacgt cactgtttcc 2940[3958] aaaaggaaaa aaataagtca gtttttggca gcaccttcat ctttctgacc tcctcctatt 3000[3959] ctgtccttgt ggacttatgt ttaacataga aaatgaatgc gtttaaaaca aaaccacttt 3060[3960] ctgcatttaa ccagtcctgg ctctctctct gctgcctctt catacgtttt ctcaagaact 3120[3961] tcagtttata attggaagag aaatttttgc tgttaatgcc agaatgagca acctcaagga 3180[3962] attgaacact tcttggaaaa tctaggtaat tcaagccctc atcaggttta caagatcatc 3240[3963] agagaaacag aggattttaa tttttagttc tggccggcta caggctccat ttctctgcct 3300[3964] tcccattgga aatagtttat ttccacattc tccactgcgt gtggtcaaag ttcctcaccc 3360[3965] agcaagggac tatagatact cgtgtcccaa ttccaaaaca caatgcacaa gctgaacttg 3420[3966] ggctgaacgt ggcgtgttga gatttggaat gaggtttcta agagccgtgt tcttcatgga 3480[3967] attttccagg ccacttggca gcttggttta ccgatggatg ggctagagat cttgtcgttt 3540[3968] cttggaagtc acagggaaga ttgaagagaa cgcttgagca tccttggcaa cagcccaggt 3600[3969] gggacctgga tgaagctttg cactcaagta ttgtcaaggg aagcttcctg tgaaccaaag 3660[3970] ttctcaggcc aaggtctcgc ccaccaaagc cagaaagtgc aagcacccgt ctacccagct 3720[3971] ctaacttgta tgtgtgagac agaccaggct tcgggggtag gaggatctgc agttgttcag 3780[3972] ccgtctttct gctggtgttg tctttctgcc atcagagaag ggacacacag cccgttcgaa 3840[3973] ggtgtgcaga gggctctgag cgccaggatg gccagggctg tttttgctac tgaaggagcg 3900[3974] tgtgtcctga actcccactt gcagggacag tccccacctt ctctatagcc ggcactggga 3960[3975] gcagccgcca gcagggaaat ctggcctgag cacaaggatg ctttagggag agatcacttc 4020[3976] agtgtgtgtg tatatttatt tgcagtacag tgcgcgcgtg tgtgtgtgtg tacgcgcacg 4080[3977] tgtgggtgag tgcgtcttct gagtgggttc tgttcagttg ctaatgaggc tcctccgctc 4140[3978] tggacacaac ccttttatag attaatttct ctgccaatta acttgtcatt ttcagtacat 4200[3979] attttactat tccacaccaa ccataattac aacaagggat ttttcttatg cactcctatg 4260[3980] catgtgaata acatgtggtg taattctgct tcttacagaa gtattactga aggtattatt 4320[3981] tccaatatta tttggtttat tatgcggatc ttttttatat atgcagtccc atcccttctg 4380[3982] tgccactcaa tgccatccag acatggtttt tccctccagg ggcctttctc tccagagggc 4440[3983] acttcggctg cctctgcttc ctctcattcg aggcccggct cttgctgaca gaataggttc 4500[3984] cgttctgggc ggtggttctc gagcctgcca ttcaaaacca aagcaaattg gagcatttct 4560[3985] cacaacatgg tattgaagtt cctttttgtt ctcaaaagtt gtgaccgtgt taaattgtac 4620[3986] tcccttagtc ctgtaaggta tgttaagtga atcgcagtta cgctgtactt ttattaatat 4680[3987] ttaacataat taaagatgga cccataagag tg 4712[3988] <210>93

[3989] <211>1398

[3990] <212>DNA

[3991] <213>人

[3992] <400>93

[3993] gtgtgaaatc ttcagagaag aatttctctt tagttctttg caagaaggta gagataaaga 60[3994] cactttttca aaaatggcaa tggtatcaga attcctcaag caggcctggt ttattgaaaa 120[3995] tgaagagcag gaatatgttc aaactgtgaa gtcatccaaa ggtggtcccg gatcagcggt 180[3996] gagcccctat cctaccttca atccatcctc ggatgtcgct gccttgcata aggccataat 240[3997] ggttaaaggt gtggatgaag caaccatcat tgacattcta actaagcgaa acaatgcaca 300[3998] gcgtcaacag atcaaagcag catatctcca ggaaacagga aagcccctgg atgaaacact 360[3999] taagaaagcc cttacaggtc accttgagga ggttgtttta gctctgctaa aaactccagc 420[4000] gcaatttgat gctgatgaac ttcgtgctgc catgaagggc cttggaactg atgaagatac 480[4001] tctaattgag attttggcat caagaactaa caaagaaatc agagacatta acagggtcta 540[4002] cagagaggaa ctgaagagag atctggccaa agacataacc tcagacacat ctggagattt 600[4003] tcggaacgct ttgctttctc ttgctaaggg tgaccgatct gaggactttg gtgtgaatga 660[4004] agacttggct gattcagatg ccagggcctt gtatgaagca ggagaaagga gaaaggggac 720[4005] agacgtaaac gtgttcaata ccatccttac caccagaagc tatccacaac ttcgcagagt 780[4006] gtttcagaaa tacaccaagt acagtaagca tgacatgaac aaagttctgg acctggagtt 840[4007] gaaaggtgac attgagaaat gcctcacagc tatcgtgaag tgcgccacaa gcaaaccagc 900[4008] tttctttgca gagaagcttc atcaagccat gaaaggtgtt ggaactcgcc ataaggcatt 960[4009] gatcaggatt atggtttccc gttctgaaat tgacatgaat gatatcaaag cattctatca 1020[4010] gaagatgtat ggtatctccc tttgccaagc catcctggat gaaaccaaag gagattatga 1080[4011] gaaaatcctg gtggctcttt gtggaggaaa ctaaacattc ccttgatggt ctcaagctat 1140[4012] gatcagaaga ctttaattat atattttcat cctataagct taaataggaa agtttcttca 1200[4013] acaggattac agtgtagcta cctacatgct gaaaaatata gcctttaaat catttttata 1260[4014] ttataactct gtataataga gataagtcca ttttttaaaa atgttttccc caaaccataa 1320[4015] aaccctatac aagttgttct agtaacaata catgagaaag atgtctatgt agctgaaaat 1380[4016] aaaatgacgt cacaagac 1398[4017] <210>94

[4018] <211>2972

[4019] <212>DNA

[4020] <213>人

[4021] <400>94

[4022] gcgcgcggct ccgatgggaa gcatgacccg ggtggcggga caagacttgc ttcccggcca 60[4023] cgcgcgctcg gccggccgtg gggcggggca taggcgtgac gtggtgtcgc gtatcgagtc 120[4024] tccgccccct tcccgcctcc ccgtatataa gacttcgccg agcactctca ctcgcacaag 180[4025] tggaccgggg tgttgggtgc tagtcggcac cagaggcaag ggtgcgagga ccacggccgg 240[4026] ctcggacgtg tgaccgcgcc tagggggtgg cagcgggcag tgcggggcgg caaggcgacc 300[4027] atggarcttt tgcggactat cacctaccag ccagccgcca gcaccaaaat gtgcgagcag 360[4028] gcgctgggca agggttgcgg aggggactcg aagaagaagc ggccgccgca gccccccgag 420[4029] gaatcgcagc cacctcagtc ccaggcgcaa gtgcccccgg cggcccctca ccaccatcac 480[4030] caccattcgc actcggggcc ggagatctcg cggattatcg tcgaccccac gactgggaag 540[4031] cgctactgcc ggggcaaagt gctgggaaag ggtggctttg caaaatgtta cgagatgaca 600[4032] gatttgacaa ataacaaagt ctacgccgca aaaattattc ctcacagcag agtagctaaa 660[4033] cctcatcaaa gggaaaagat tgacaaagaa atagagcttc acagaattct tcatcataag 720[4034] catgtagtgc agttttacca ctacttcgag gacaaagaaa acatttacat tctcttggaa 780[4035] tactgcagta gaaggtcaat ggctcatatt ttgaaagcaa gaaaggtgtt gacagagcca 840[4036] gaagttcgat actacctcag gcagattgtg tctggactga aataccttca tgaacaagaa 900[4037] atcttgcaca gagatctcaa actagggaac ttttttatta atgaagccat ggaactaaaa 960[4038] gttggggact tcggtctggc agccaggcta gaacccytgg aacacagaag gagaacgata 1020[4039] tgtggtaccc caaattatct ctctcctgaa gtcctcaaca aacaaggaca tggctgtgaa 1080[4040] tcagacattt gggccctggg ctgtgtaatg tatacaatgt tactagggag gcccccattt 1140[4041] gaaactacaa atctcaaaga aacttatagg tgcataaggg aagcaaggta tacaatgccg 1200[4042] tcctcattgc tggctcctgc caagcactta attgctagta tgttgtccaa aaacccagag 1260[4043] gatcgtccca gtttggatga catcattcga catgactttt ttttgcaggg cttcactccg 1320[4044] gacagactgt cttctagctg ttgtcataca gttccagatt tccacttatc aagcccagct 1380[4045] aagaatttct ttaagaaagc agctgctgct ctttttggtg gcaaaaaaga caaagcaaga 1440[4046] tatattgaca cacataatag agtgtctaaa gaagatgaag acatctacaa gcttaggcat 1500[4047] gatttgaaaa agacttcaat aactcagcaa cccagcaaac acaggacaga tgaggagctc 1560[4048] cagccaccta ccaccacagt tgccaggtct ggaacacccg cagtagaaaa caagcagcag 1620[4049] attggggatg ctattcggat gatagtcaga gggactcttg gcagctgtag cagcagcagt 1680[4050] gaatgccttg aagacagtac catgggaagt gttgcagaca cagtggcaag ggttcttcgg 1740[4051] ggatgtctgg aaaacatgcc ggaagctgat tgcattccca aagagcagct gagcacatca 1800[4052] tttcagtggg tcaccaaatg ggttgattac tctaacaaat atggctttgg gtaccagctc 1860[4053] tcagaccaca ccgtcggtgt ccttttcaac aatggtgctc acatgagcct ccttccagac 1920[4054] aaaaaaacag ttcactatta cgcagagctt ggccaatgct cagttttccc agcaacagat 1980[4055] gctcctgagc aatttattag tcaagtgacg gtgctgaaat acttttctca ttacatggag 2040[4056] gagaacctca tggatggtgg agatctgcct agtgttactg atattcgaag acctcggctc 2100[4057] tacctccttc agtggctaaa atctgataag gccctaatga tgctctttaa tgatggcacc 2160[4058] tttcaggtga atttctacca tgatcataca aaaatcatca tctgtagcca aaatgaagaa 2220[4059] taccttctca cctacatcaa tgaggatagg atatctacaa ctttcaggct gacaactctg 2280[4060] ctgatgtctg gctgttcatc agaattaaaa aatcgaatgg aatatgccct gaacatgctc 2340[4061] ttacaaagat gtaactgaaa gacttttcga atggacccta tgggactcct cttttccact 2400[4062] gtgagatcta cagggaagcc aaaagaatga tctagagtat gttgaagaag atggacatgt 2460[4063] ggtggtacga aaacaattcc cctgtggcct gctggactgg gtggaaccca gaaccaggct 2520[4064] aaggcataca gttcttgact ttggacaatc ccaagagtga accagaatgc agttttcctt 2580[4065] gagatacctg ttttaaaagg tttttcagac aattttgcag aaaggtgcat tgattcttaa 2640[4066] attctctctg ttgagagcat ttcagccaga ggactttgga actgtgaata tacttcctga 2700[4067] aggggaggga gaagggagga agctcccatg ttgtttaaag gctgtaattg gagcagcttt 2760[4068] tggctgcgta actgtgaact atggccatat ataatttttt ttcattaatt tttgaagata 2820[4069] cttgtggctg gaaaagtgca ttccttgtta ataaactttt tatttattac agcccaaaga 2880[4070] gcagtattta ttatcaaaat gtcttttttt ttatgttgac cattttaaac cgttggcaat 2940[4071] aaagagtatg aaaacgcaaa aaaaaaaaaa aa 2972