Pharmaceutical preparation of active substance on surface of lung
专利汇可以提供Pharmaceutical preparation of active substance on surface of lung专利检索，专利查询，专利分析的服务。并且PURPOSE: The titled pharmaceutical preparation suspensible in physiologic salt solution in a short time without causing deterioration of active substance on the surface of the lung in ability to reduce surface tension in air cells, having low toxicity and improved solidification state, obtained by adding sugar alcohol or lactose to the active substance on the surface of the lung.
CONSTITUTION: The titled pharmaceutical preparation containing an active substance on the surface of the lung and a sugaralcohol (e.g., mannitol, xylitol, or sorbitol) or lactose in a weight ratio of 1:(0.4W2.0) (preferably 0.8W1.5). The pharmaceutical preparation is obtained by suspending and dissolving uniformly given amounts of the active substance on the surface of the lung and the sugaralcohol of lactose in water or an ethanol-water mixed solution (blending volume ratio of 1:4W9) at ≤40°C, weighting and packing the prepared suspension into sealed containers such as vials or ampuls, and after drying and solidifying the solution by lyophilization, sealing the containers.
COPYRIGHT: (C)1985,JPO&Japio，下面是Pharmaceutical preparation of active substance on surface of lung专利的具体信息内容。
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