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Di-hydro triazine derivatives

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专利汇可以提供Di-hydro triazine derivatives专利检索,专利查询,专利分析的服务。并且N-substituted symmetrical di-hydrotriazine derivatives and salts are described having anti-malarial and antibacterial activity as well as effectiveness against some fungi and protozoa. A representative compound is 4,5-diamino-1,2-dihydro-2,2-dimethyl1-(3''-(2,4,5-trichlorophenoxy)propyloxy)-1,3,5-triazine hydrobromide. The compounds can be prepared by reacting a substituted diguanide with a carbonyl compound in the presence of an acid catalyst to form a substituted triazine which may then be salified or acylated.,下面是Di-hydro triazine derivatives专利的具体信息内容。

  • 2. A compound of claim 1, wherein R3 and R4 are both methyl, R2 is alkylene of two to four carbon atoms and X is oxygen.
  • 3. A compound of claim 1, wherein R1 is phenyl or halogeno-, alkyl-, nitro-, methoxyl- or trifluoromethyl-phenyl.
  • 4. A compound of claim 3, wherein R1 is mono-, di-, tri- or tetrahalogeno-phenyl.
  • 5. A compound of claim 4, wherein R1 is dichlorophenyl or trichlorophenyl.
  • 6. A compound of claim 1 which is 4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3''-(2,4,5-trichlorophenoxy) -propyloxy)-1,3,5-triazine or a non-toxic acid salt or an acetyl derivative thereof.
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