Aerobic fermentation apparatus
阅读：327发布：2023-06-20
专利汇可以提供Aerobic fermentation apparatus专利检索，专利查询，专利分析的服务。并且Yeasts are grown aseptically by an improved aerobic fermentation process, employing an aqueous ethanolic substrate fortified with nutrient elements, preferably under oxygen-limited conditions. Fermentation is effected in a continuous manner in a zone maintained under super-atmospheric pressure. Micro-nutrients are added to the substrate separately from macronutrients as a sterile aqueous solution, preferably containing iron as ferric citrate. A preferred yeast is Candida utilis.，下面是Aerobic fermentation apparatus专利的具体信息内容。
1. IN A CONTINUOUS AEROBIC FERMENTATION APPARATUS, INCLUDING A VERTICAL CYLINDRICAL FERMENTOR VESSEL, AN INTERNAL COOLING APPARATUS IN COMBINATION THEREWITH, SAID COOLING APPARATUS COMPRISING, A. A TOP CIRCULAR HEADER PIPE DISPOSE HORIZONTALLY WITHIN AN UPPER SECTION OF THE FERMENTOR VESSEL; B. A BOTTOM CIRCULAR HEADER PIPER, ALIGNED AXIALLY WITH AND HAVING SUBTANTIALLY THE SAME MEANS DIAMETER AS THE TOP HEADER PIPE, DISPOSED HORIZONTALLY WITHIN LOWER SECTION OF THE FERMENTOR VESSEL; C. A PLURALITY OF CONNECTOR PIPES, DISPOSED VERTICALLY IN A SPACE RELATIONSHIP AND SEVERALLY ATTACHING THE BOTTOM CIRCULAR HEADER PIPE TO THE TOP CIRCULAR HEADER PIPE, BEING ARRANGED IN PARALLEL ROWS ALONG THE CIRCUMFERENCE DESCRIBED BY THE CIRCULAR HEADER PIPES IN SUFFICIENT NUMBER TO PROVIDE A TOTAL CROSS-SECTION AREA SUBSTANTIALLY EQUAL TO THE CROSS-SECTION AREA OF EITHER OF THE HEADER PIPES; D. AN INLET PIPE, EXTENDING HORIZONTALLY THROUGH THE FERMENTOR VESSEL WALL IN SEALED RELATION THERETO IN THE PLANE OF THE BOTTOM HEADER PIPE AND ATTACHED AT ONE END TO THE HEADER PIPE; E. AN EXIT PIPE, ATTACHED AT ONE END TO THE TOP CIRCULAR HEADER PIPE AND EXTENDING HORZONTALLY THEREFROM AND PASSING THROUGH THE FERMENTOR VESSEL WALL IN SEALED RELATION THEREWITH; AND F. PUMPING AND COMPRESSING MEANS LOCATED EXTERNALLY OF THE FERMENTOR VESSEL AND ATTACHED EXTERNALL THEREOF TO THE EXTENDED ENDS OF BOTH THE INLET PIPE AND THE EXIT PIPE, IN ORDER TO PROVIDE A CONTINUOUSLY FLOWING SYSTEM FOR CONTAINMMENT OF COOLANT LIQUID AND VAPOR PHASES, WHEREBY EFFICIENT INDIRECT HEAT EXCHANGE IS EFFECTED WITH A FERMENTATION LIQUOR CONTAINED IN THE SECTIONS OF THE FERMENTOR VESSEL AND SURROUND THE INTERNAL COOLING APPARATUS, SO THAT A SUBSTANTIALLY CONSTANT TEMPERATURE IS MAINTAINED WITHIN THE FERMENTATION LIQUOR THROUGHOUT THE COURSE OF THE AEROBIC FEMENTATION PROCESSING; AND SAID FERMENTOR VESSEL COMPRISING,
1. AN AIR INLET AND OUTLET MEANS ATTACHED TO THE TOP SECTION;
2. an agitator means located directly below the bottom circular header pipe;
2. The apparatus of claim 1 wherein the top and bottom circular header pipes are disposed within a fermentor vessel having a capacity of about 50,000 gallons and are fashioned from pipe having a diameter of about two feet to describe a circle whose outside diameter is about 16 feet.
2. A AN AGITATOR MEANS LOCATED DIRECTLY BELOW THE BOTTOM CIRCULAR HEADER PIPE;
3. an air sparger means attached to the air entry means within the bottom section and situated directly beneath the agitator means;
3. AN AIR SPARGER MEANS ATTACHED TO THE AIR ENTRY MEANS WITHIN THE BOTTOM SECTION AND SITUATED DIRECTLY BENEATH THE AGITATOR MEANS;
3. The apparatus of claim 2 wherein the vertical connector pipes are fashioned from pipe having a diameter of about 1 inch and are arranged in two parallel rows about the circumference of the circular header pipes.
4. a nutrient inlet means attached to the top section;
4. A NUTRIENT INLET MEANS ATTACHED TO TOP SECTION;
5. A FERMENTATION BROTH OUTLET MEANS ATTACHED TO THE BOTTTOM SECTION; AND
5. a fermentation broth outlet means attached to the bottom section; and
6. two vertical baffle means located along the interior wall of the vessel on either side of the internal cooling apparatus.
6. TWO VERTICAL BAFFLE MEANS LOCATED ALONG THE INTERIOR WALL OF THE VESSEL ON EITHER SIDE OF THE INTERNAL COOLING APPARATUS.
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