DEPROTECTION METHOD FOR PROTECTED HYDROXYL GROUP

申请号 EP12774758 申请日 2012-04-19 公开(公告)号 EP2700628A4 公开(公告)日 2014-10-08
申请人 ASAHI GLASS CO LTD; 发明人 ISHIBASHI YUICHIRO; MATSUMURA YASUSHI;
摘要 To deprotect an alcoholic hydroxyl group protected by a t-butyldimethylsilyl group without influencing a functional group unstable to an acid. In the presence of a solvent, an alcohol having a hydroxyl group protected by a t-butyldimethylsilyl group is deprotected in the presence of an acid or an acid salt having a pKa of from 1.0 to 3.0 in water.
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