Dynemicin c antitumor antibiotic |
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| 申请号 | JP34934691 | 申请日 | 1991-11-05 | 公开(公告)号 | JPH04368388A | 公开(公告)日 | 1992-12-21 |
| 申请人 | Bristol Myers Squibb Co; | 发明人 | SAITO KYOICHIRO; MIYAGI TAKEO; YAMAMOTO HARUAKI; ODA NAOMI; | ||||
| 摘要 | PURPOSE: To obtain a novel compd. having excellent antibacterial activity, antifungal activity and antitumor activity. CONSTITUTION: A compd. of the formula. For example, Dynemicin C. The compd. of the formula is obtd. by culturing, for example, Micromonospora chermina F1085 (ATCC-55077) or its variant in an aq. nutrient medium contg. an assimilable carbon source or nitrogen source under an intra-liquid aerobic condition preferably at about 28°C for 3 to 4 days and executing isolation and refining with chromatography, etc. A medicinal compsn. is obtd. by combining a carrier and diluent with the effective amt. of the compd. of the formula. COPYRIGHT: (C)1992,JPO |
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