MAMMALIAN GENES AND GENE PRODUCTS INVOLVED IN INFECTION

申请号 PCT/US2012048507 申请日 2012-07-27 公开(公告)号 WO2013066442A3 公开(公告)日 2013-07-18
申请人 HODGE THOMAS W; MCDONALD NATALIE J; MURRAY JAMES L; SHAW MICHAEL W; RUBIN DONALD H; SANCHEZ ANTHONY; 发明人 HODGE THOMAS W; MCDONALD NATALIE J; MURRAY JAMES L; SHAW MICHAEL W; RUBIN DONALD H; SANCHEZ ANTHONY;
摘要 The present disclosure relates to mammalian genes and gene products that are involved in infection or are otherwise associated with the life cycle of one or more pathogens. Disclosed herein are methods of reducing infection of a cell by a pathogen, for example to treat or prevent a pathogen infection. Exemplary pathogens include HIV-1, HIV-2, influenza A, Marburg virus and Ebola virus. The disclosure also relates to methods of identifying agents involved in pathogen infection.
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