COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY

申请号 US14676255 申请日 2015-04-01 公开(公告)号 US20150342993A1 公开(公告)日 2015-12-03
申请人 MEMORIAL SLOAN-KETTERING CANCER CENTER; 发明人 Christopher C. Kloss; Michael Sadelain;
摘要 The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen recognizing receptor and one of a chimeric costimulatory receptor. Methods of using the immunoresponsive cell include those for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired.
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