COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY |
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申请号 | US14676255 | 申请日 | 2015-04-01 | 公开(公告)号 | US20150342993A1 | 公开(公告)日 | 2015-12-03 |
申请人 | MEMORIAL SLOAN-KETTERING CANCER CENTER; | 发明人 | Christopher C. Kloss; Michael Sadelain; | ||||
摘要 | The present invention provides immunoresponsive cells, including T cells, cytotoxic T cells, regulatory T cells, and Natural Killer (NK) cells, expressing at least one of an antigen recognizing receptor and one of a chimeric costimulatory receptor. Methods of using the immunoresponsive cell include those for the treatment of neoplasia and other pathologies where an increase in an antigen-specific immune response is desired. | ||||||
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说明书全文 |