FLUOROGENIC PH SENSITIVE DYES AND THEIR METHOD OF USE

申请号 US15899021 申请日 2018-02-19 公开(公告)号 US20180238912A1 公开(公告)日 2018-08-23
申请人 LIFE TECHNOLOGIES CORPORATION; 发明人 Jeffrey DZUBAY; Kyle Gee; Vladimir Martin; Aleksey Rukavishnikov; Daniel Beacham;
摘要 A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: wherein the variables are described throughout the application.
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