子分类：
| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 121 | MANUFACTURING DEVICE AND PROCESS FOR PERSONALIZED DELIVERY VECTOR-BASED IMMUNOTHERAPY | US15326955 | 2016-06-24 | US20170204361A1 | 2017-07-20 | Anil EAPEN; Robert PETIT; Mayo PUJOLS |
| This invention provides a system of providing and a process of creating personalized immunotherapeutic compositions for a subject having a disease or condition, including therapeutic vaccine delivery vectors comprising gene expression constructs expressing peptides associated with one or more neo-epitopes or peptides containing mutations that are specific to an subject's cancer or unhealthy tissue. The invention further provides a scalable fully enclosed single use cell growth system, wherein the entire process of manufacturing of personalized immunotherapeutic compositions, up to and including dispensing said composition into containers for patient delivery is carried out within a single enclosed fluid flow path. | ||||||
| 122 | Carton | US29514236 | 2015-01-09 | USD792213S1 | 2017-07-18 | Michael R. Schmal; O'Neal Alexander; Mark Baldino; Michael Cerio; John Murdick Holley, Jr.; Frank N. Moncrief; Raymond S. Kastanek; Colin Ford |
| 123 | Kits including implantable medical devices and antioxidants | US13759898 | 2013-02-05 | US09655751B2 | 2017-05-23 | Ni Ding |
| Methods of incorporating an antioxidant into a medical device including a polymer are described, and methods of packaging medical devices. | ||||||
| 124 | METHOD AND SYSTEM FOR DECONTAMINATING CAPS OR NECKS OF CONTAINERS BY PULSED ELECTRON BOMBARDMENT | US15317291 | 2015-05-19 | US20170136135A1 | 2017-05-18 | Guy FEUILLOLEY |
| A method for decontaminating caps (2) or necks of containers by electron bombardment, the method including: an operation of the passage or positioning of the caps (2) or necks of containers in front of an electron bombardment window (8), the opening of the caps (2) or necks of the containers facing the window (8); and an operation of electron bombardment of the caps (2) or necks of the containers, during the passage or positioning of the caps or necks of the containers in front of the window (8); the bombardment being carried out by way of a pulsed electric field including a series of electrical pulses of determined frequency, duration and intensity. | ||||||
| 125 | Sterilizer and Sterilization Method | US15240217 | 2016-08-18 | US20170049916A1 | 2017-02-23 | Takeshi Ikeda |
| A sterilizer includes: a first sterilization unit configured to house an object to be sterilized; a second sterilization unit configured to house a bag that houses the object to be sterilized; and a sterilizing gas supply system configured to supply a sterilizing gas to both of the first sterilization unit and the second sterilization unit. | ||||||
| 126 | Carton with article protection feature | US14490970 | 2014-09-19 | US09573744B2 | 2017-02-21 | Michael R. Schmal; O'Neal Alexander; Mark Baldino; Michael Cerio; John Murdick Holley, Jr.; Frank N. Moncrief; Raymond S. Kastanek; Colin Ford |
| A carton for containing at least one article. The carton comprises at least one panel that can form an interior of the carton. The carton comprises at least one protection feature for protecting the articles from breakage. The article protection feature can comprise at least one feature in end flaps of the carton. The article protection feature can comprise an article protection flap foldably connected to the at least one panel. The article protection flap can be moveable between a first position and a second position wherein the article protection flap is folded relative to the at least one panel. | ||||||
| 127 | Stable therapeutic formulations | US14160326 | 2014-01-21 | US09573717B2 | 2017-02-21 | Mahmoud Ameri; Michel J. N. Cormier; Scott Sellers; Yuh-Fun Maa |
| Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents. | ||||||
| 128 | PACKING BOX, PACKING METHOD AND UNPACKING METHOD | US15206251 | 2016-07-09 | US20170008663A1 | 2017-01-12 | Tetsuya Atsumi |
| A packing box including lattice members which are arranged in a stacked state into stages, a stage-partition plate which is arranged between the stages of the lattice members, two or more inner tubular-trunk frames which are provided in a stacking direction of the lattice members to surround one or more stages of the lattice members, an outer tubular-trunk frame surrounding an outside of two or more stages of the inner tubular-trunk frames, a bottom lid which is arranged under the outer tubular-trunk frame, and a top lid which is arranged on the outer tubular-trunk frame. | ||||||
| 129 | IN-BOTTLE PASTEURIZATION | US14901711 | 2014-06-25 | US20160366920A1 | 2016-12-22 | Mary Tanzosh; Holly Symolon; Peter Simpson |
| A system and method for producing a packaged food article or beverage may include processing a first food source including a spoilage microorganism along a first processing path, which may limit temperature of the first food source to be below a temperature level that causes the spoilage microorganism to be inactivated. A second food source may be processed along a second processing path, which may heat the second food source to be in a predetermined temperature range that causes spoilage microorganisms in the second food source to be substantially inactivated when in the predetermined temperature range for a predetermined period of time. A package may be filled with the first and the second food sources. The second food source, when mixed with the first food source, may be in the predetermined temperature range for the predetermined period of time in the package to inactivate the spoilage microorganism. | ||||||
| 130 | METHOD OF PACKAGING FOOD | US15243648 | 2016-08-22 | US20160353732A1 | 2016-12-08 | Maria Paula Junqueira Conceicao Gonsalves; Andrea Marcarena Tapia Ulloa |
| The invention proposes a container further extending the shelf life of foods, particularly berries, by including an active agent having antifungal capability into the container surface so that when the fruit is packaged inside the container it is permanently exerted an antifungal effect over the surface, which is the place on the longer determinants occurs, but also contributing to preserve the general environment. Also it proposes a preparation process and its use. | ||||||
| 131 | Protective Box for Surgery | US15234351 | 2016-08-11 | US20160346055A1 | 2016-12-01 | Daniel R. Jacobson |
| The present invention is directed to providing a sterile container protecting various surgical grafts, implants and devices from incidental contamination and damage during operative procedures. The design includes an inner box to contain the items, and an outer box to protect the exterior of the inner box from contamination in the event of fall or other contamination, such as from airborne particles or liquids, fall from the sterile field, or by non-sterile handling. In the event of fall or contamination of the outer box, the surgical staff will be able to recover the inner box and its contents in sterile and unspoiled condition without difficulty. | ||||||
| 132 | Method of forming a carton with article protection feature | US14620595 | 2015-02-12 | US09499319B2 | 2016-11-22 | Michael R. Schmal; O'Neal Alexander; Mark Baldino; Michael Cerio; John Murdick Holley, Jr.; Frank N. Moncrief; Raymond S. Kastanek; Colin Ford |
| A method of forming a carton. The method includes obtaining a blank having at least one panel and at least one article protection flap foldably connected to the at least one panel. The method includes positioning the at least one panel to at least partially form an interior space of the carton, loading at least one article in the interior space, and folding the at least one article protection flap relative to the at least one panel after the loading the at least one article. The folding includes moving the article protection flap from a first position that is substantially parallel to the at least one panel to a second position wherein the article protection flap is folded relative to the at least one panel. | ||||||
| 133 | Method of forming a carton with article protection flap | US14609674 | 2015-01-30 | US09481501B2 | 2016-11-01 | Michael R. Schmal; O'Neal Alexander; Mark Baldino; Michael Cerio; John Murdick Holley, Jr.; Frank N. Moncrief; Raymond S. Kastanek; Colin Ford |
| A method of forming a carton. The method comprises obtaining a blank comprising a plurality of panels comprising a bottom panel, a first side panel, a second side panel, a top panel, at least two first end flaps, at least two second end flap, and at least one article protection flap foldably connected to the bottom panel. The method comprises positioning the plurality of panels to form an interior space of the carton, loading a plurality of beverage bottles into the interior space, closing a first end of the carton, closing a second end of the carton, and tightening the carton by folding the at least one article protection flap into the interior space after the loading of the plurality of beverage bottles. | ||||||
| 134 | Aseptic transfer bead for plastic containers | US14813576 | 2015-07-30 | US09475600B2 | 2016-10-25 | Edward Roubal; Larry Taylor |
| A plastic container includes a neck with an opening to an interior of the container, where the neck opening having a first diameter and a second diameter of different lengths. A shoulder portion surrounds the neck of the plastic container. A transfer bead is located on the neck above the shoulder portion where the first diameter of the neck opening is above the transfer bead and the second diameter is below the transfer bead. The transfer bead is advantageously shaped and sized so as to facilitate application and removal of a sterilization solution during the aseptic packaging process. | ||||||
| 135 | Trolley and method of using the trolley for vertical rolling | US14284487 | 2014-05-22 | US09446871B2 | 2016-09-20 | Claude Granger; Jean Roy |
| A trolley for supporting the plate during vertical rolling of the plate is provided. In one embodiment, the trolley can include a support body configured to provide support for the trolley; a plurality of wheels configured to allow the trolley to move across a floor; a lifting arm supported by the support body, wherein the lifting arm is movable about a first position and a second position; a pump handle configured to raise the lifting arm between the first position and the second position; and a plate holder configured to move with the lifting arm and hold the plate in place relative to the trolley. | ||||||
| 136 | Protective box for surgery | US14287668 | 2014-05-27 | US09414893B2 | 2016-08-16 | Daniel R. Jacobson |
| The present invention is directed to providing a sterile container protecting various surgical grafts, implants and devices from incidental contamination and damage during operative procedures. The design includes an inner box to contain the items, and an outer box to protect the exterior of the inner box from contamination in the event of fall or other contamination, such as from airborne particles or liquids, fall from the sterile field, or by non-sterile handling. In the event of fall or contamination of the outer box, the surgical staff will be able to recover the inner box and its contents in sterile and unspoiled condition without difficulty. | ||||||
| 137 | Reduced temperature sterilization of stents | US14263952 | 2014-04-28 | US09339568B2 | 2016-05-17 | Bin Huang; Abigail Freeman; Daniel Castro; David C. Gale |
| Methods and systems for reduced temperature radiation sterilization of stents are disclosed. | ||||||
| 138 | Method for building air separating units in a remote manufacturing yard | US14284510 | 2014-05-22 | US09302798B2 | 2016-04-05 | Claude Granger; Yves Hardy; Emmanuelle Bromet; Jean Roy; Philippe Grigoletto; Qun-Fang Li; Herve Ferriere; Sylvain Made |
| A method for fabricating a distillation column in a remote location away from a permanent manufacturing facility is provided. In one embodiment, the method can include the steps of: forming a plurality of column sections each having a diameter D, each column section comprising a plurality of courses that have been horizontally welded together, wherein each course is comprised of two or more partial shells that have been vertically welded together, wherein each of the two or more partial shells was created by vertically rolling a rectangular plate having a length of at least ( 1 N π · D ) , wherein N is the number of partial shells used to form the course; installing a distributor and packing in each column section to form a plurality of packed column sections; and stacking the plurality of packed column sections to form a column. | ||||||
| 139 | Carton with article protection feature | US13419740 | 2012-03-14 | US09284084B2 | 2016-03-15 | Michael R. Schmal; O'Neal Alexander; Mark Baldino; Michael Cerio; John Murdick Holley, Jr.; Frank N. Moncrief; Raymond S. Kastanek; Colin Ford |
| A carton for containing at least one article. The carton comprises at least one panel that can form an interior of the carton. The carton comprises at least one protection feature for protecting the articles from breakage. The article protection feature can comprise at least one feature in end flaps of the carton. The article protection feature can comprise an article protection flap foldably connected to the at least one panel. The article protection flap can be moveable between a first position and a second position wherein the article protection flap is folded relative to the at least one panel. | ||||||
| 140 | GEL CARD FILLING DEVICE COMPRISING AN IONIZER | US14861233 | 2015-09-22 | US20160011226A1 | 2016-01-14 | Frédéric BUFFIERE; Serge PETIT; Jean-Michel BRISEBRAT |
| The invention relates to a device for filling at least one receptacle (12) of gel card type initially sealed by a cap. The invention is characterized by the fact that the filling device comprises a piercing member (110) for perforating the cap, means (120) for eliminating the electrostatic charges capable of being borne by the receptacle, and filling means (130) for filling the receptacle after perforation of the cap and elimination of the electrostatic charges. | ||||||
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