序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
101 Composite melanin pigment in the form of particles comprising a wax-based spherical core, preparation processes and cosmetic uses US991303 1997-12-16 US5954871A 1999-09-21 Luc Nicolas-Morgantini; Alain Lety; Guy Vanlerberghe
A composite melanin pigment in the form of particles comprising a spherical core less than 1 .mu.m in diameter, which comprises at least one wax and at least one surfactant, and an outer layer which envelops the core, which comprises at least one compound resulting from the oxidative polymerization of a melanin pigment precursor; and uses of the pigment in powder form or in the form of an aqueous dispersion, in cosmetic compositions, in particular in dye products and/or make-up products and/or care products for keratin substances such as the skin, the hair and the nails.
102 Products derived from 2-imino-2,3-dihydro-1H-indoles, processes for their preparation, their use in cosmetics and cosmetic compositions using them US916215 1997-08-22 US5919469A 1999-07-06 Alain Lagrange
Products derived from 2-imino-2,3-dihydro-1H-indoles resulting from the oxidative polymerization of at least one compound of formula (I) or (II) below: ##STR1## in which: R.sub.1, R.sub.2 and R.sub.3 denote hydrogen, alkyl, carboxyl, alkoxycarbonyl, monohydroxyalkyl, polyhydroxyalkyl, alkoxyalkyl, monoalkylaminoalkyl or dialkylaminoalkyl; R'.sub.3 and R.sub.4 denote alkyl, carboxyl, alkoxycarbonyl, monohydroxyalkyl, polyhydroxyalkyl, alkoxyalkyl, monoalkylaminoalkyl or dialkylaminoalkyl;R.sub.5 denotes hydrogen, alkyl, monohydroxyalkyl, polyhydroxyalkyl, alkoxyalkyl, monoalkylaminoalkyl or dialkylaminoalkyl;and to the addition salts thereof with an acid, as well as to their uses in cosmetics for making up the exoskeleton and/or the skin.
103 Process for the preparation of a melanic pigment of small particle size and its use in cosmetics US815662 1997-03-10 US5776241A 1998-07-07 Paolo Giacomoni; Laurent Marrot; Myriam Mellul; Annick Colette
Process for the preparation of a melanic pigment of small particle size and its use in cosmetics. The subject of the present invention is a process for the preparation of a melanic pigment of very small particle size in which 100% of the particles have a particle size smaller than 1.mu.m, consisting in dissolving a melanin of natural and/or synthetic origin in an aqueous medium containing at least one alkalifying agent and/or at least one sequestering agent, and in precipitating the melanin thus dissolved by addition of at least one alkaline-earth metal salt. Another subject of the invention is the use of this pigment in compositions for cosmetic treatments and for dyeing hair.
104 Melanin enhanced photothermolysis hair removal US634569 1996-04-18 US5766214A 1998-06-16 Thomas L. Mehl, Sr.; Nardo Zaias
A method of permanent hair removal which uses a high energy light source projected at the skin to cause death of the hair follicle by photothermolysis. The process uses either incoherent or coherent light energy. Additional melanin is added to the skin by a process which delivers the melanin to the region of the hair follicle thereby enhancing that area as a light absorbing target. Collateral damage to the surrounding skin tissue is minimized. The delivery process uses liposomes selected particularly to encapsulate and carry melanin to the target region. The invention also encompasses a general method of deleterious tissue destruction by selective introduction of melanin and subsequent photothermolysis.
105 Method to deliver compositions conferring resistance to alopecia to hair follicles US486520 1995-06-07 US5753263A 1998-05-19 Valeryi Lishko; Lingna Li
The invention describes a method to deliver a composition selectively to hair follicles using a liposomal formulation. Proteins which are cell cycle inhibitors are products of the multi-drug resistance gene or the recombinant materials for their production are targeted to hair follicles by encapsulating them in liposomes.
106 Methods and compositions for reducing pyrimidine photoproducts US440626 1995-05-15 US5629314A 1997-05-13 Frances C. Gaskin
This invention is directed to a method for reducing pyrimidine photoproducts comprising applying an effective amount of melanin to human skin prior to exposure to ultraviolet rays, wherein said melanin is in a vehicle suitable for topical application and measuring the amount of pyrimidine photoproducts as compared to a control sample. Another embodiment of this invention is where the vehicle is an ointment, cream or lotion. For the purpose of this invention, measuring also means determining, and/or quantifying.This invention is also directed to a method for reducing pyrimidine photoproducts comprising applying an effective amount of melanin and solubilizing substance to human skin prior to exposure to ultraviolet rays, wherein said substance for solubilizing melanin is selected from the group consisting of triethanolamine and trypsin, wherein said solubilizing substance is present in an amount sufficient to solubilize the melanin thereby producing melanin solubilized by said substance, wherein said melanin and solubilizing substance is in a vehicle suitable for topical application and measuring the amount of pyrimidine photoproducts as compared to a control sample. Another embodiment of this invention is where the vehicle is an ointment, cream or lotion. For the purpose of this invention, measuring also means determining, and/or quantifying.
107 Soluble melanin US16348 1993-02-11 US5618519A 1997-04-08 John M. Pawelek; Seth J. Orlow
A melanin that is soluble in an aqueous solution at a pH of at least 5 to 9 at a temperature of 0.degree. to 100.degree. C. The melanin is further characterized by being capable of being filtered through at least a 0.45 micron size filter. Still further, the melanin is characterized by having a molecular weight of greater than 10,000 kilodaltons. The melanin is useful for providing a naturally-appearing tan to mammalian skin and hair. Such melanin can be produced by combining dopachrome and 5,6-dihydroxyindole (or allowing dopachrome to spontaneously form 5,6-dihydroxyindole) and an appropriate enzyme or by combining 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid or by incubating 5,6-dihydroxyindole-2-carboxylic acid alone. The melanin is also useful for providing a sun-screen to mammalian skin and hair.
108 Electrophoretic apparatus and method for applying therapeutic, cosmetic and dyeing solutions to hair US369446 1995-01-06 US5472456A 1995-12-05 Edvin G. Larsky; Gary Van Sickler
A method of introducing therapeutic, cosmetic, and dyeing agents in buffer medium created by the electrophoretic flow of these solutions into the hair. The result is to increase the therapeutic effect of treatments for the hair including hair growth and regeneration. Other results include the even and stable dyeing of hair due to the increased adhering properties created through the electrophoretic device and the solutions used with it. These solutions include, but are not limited to, those dyeing and therapeutic agents which do not readily stick to the hair or those which may form unstable compounds.
109 Fine dispersion of melanin pigments, its preparation and its use in cosmetics US211168 1994-09-19 US5451254A 1995-09-19 Herve Andrean; Didier Candau; Myrian Mellul; Christos Papantoniou; Bertrand Piot
The invention relates to a dispersion of melanic pigments containing in a medium selected amongst: a) the straight or branched monoalcohols comprising at least 3 carbon atoms; the straight or branched polyols comprising at least 2 carbon atoms; the saturated or unsaturated cycloaliphatic alcohols comprising at least 6 carbon atoms; the aromatic alcohols comprising at least 6 carbon atoms; the C.sub.8 -C.sub.22 fatty acid esters and C.sub.1 -C.sub.6 alcohol esters or the C.sub.2 -C.sub.6 polyol esters; the C.sub.1 -C.sub.6 aliphatic acid esters or the C.sub.8 -C.sub.22 aromatic acid and fatty alcohol esters; the C.sub.8 -C.sub.22 fatty acid esters and the C.sub.8 -C.sub.22 fatty alcohol esters, the C.sub.6 -C.sub.22 polyacid and alcohol esters, the hydroxylated fatty acid diesters; the straight or branched paraffins comprising at least 8 carbon atoms; the silicone oils; and the mixture of these different organic compounds, or b) an emulsion comprised of a liquid defined under a), non water miscible, water and an emulsifying agent, a melanic pigment in the form of particles in which at least 75% of the particles have a grain size smaller than 10 microns. The invention also relates to a method for the preparation and the utilization of such dispersion in cosmetics.
110 Cosmetics based on naturally derived melanin-coated pigments US150114 1993-11-24 US5380359A 1995-01-10 Shinkichi Honda; Yoichiro Takekoshi; Yoichiro Arai
A melanin-coated pigment obtained by coating a carrier with a readily alkali-soluble natural melanin, and a cosmetic containing the pigment are provided. The melanin-coated pigment is highly safe and has high coloring and high saturation tone, and a cosmetic which contains it is also expected to have ultraviolet-ray-absorbing and anti-oxidizing effects.
111 Color modified melanins and methods for their preparation and use US990496 1992-12-14 US5240715A 1993-08-31 Ago B. Ahene; Miles Chedekel
Color modified melanin compositions are produced by exposure of a natural or synthetic melanin starting material to a color modifying agent under controlled conditions. By treating the melanin starting materials for a preselected time period, melanin products having a desired final color may be obtained. The color modified melanin may be employed in a variety of cosmetic and other topically applied formulations. Prior to incorporation in such formulations, the color modified melanins will be cleaned to remove the color modifying agent and low molecular weight degradation products of the melanin.
112 Soluble melanin US674489 1991-03-25 US5225435A 1993-07-06 John M. Pawelek; Seth J. Orlow
A melanin that is soluble in an aqueous solution at a pH of at least 5 to 9 at a temperature of 0 to 100.degree. C. The melanin is further characterized by being capable of being filtered through at least a 0.45 micron size filter. Still further, the melanin is characterized by having a molecular weight of greater than 10,000 kilodaltons. The melanin is useful for providing a naturally-appearing tan to mammalian skin and hair. Such melanin can be produced by combining dopachrome and 5,6-dihydroxyindole (or allowing dopachrome to spontaneously form 5,6-dihydroxyindole) and an appropriate enzyme or by combining 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid or by incubating 5,6-dihydroxyindole-2-carboxylic acid alone. The melanin is also useful for providing a sun-screen to mammalian skin and hair, to treat post-inflammatory hypo- and hyperpigmentation, to tint glass and plastic, to protect industrial materials against ultraviolet damage, and as a coloring agent in foodstuffs such as coffee, tea, soda, whiskey and liquors.
113 Composition based on cationic polymers, anionic polymers and waxes for use in cosmetics US225583 1988-07-28 US4871536A 1989-10-03 Jean-Pierre Arraudeau; Jeanne Patraud; Louis Le Gall
The invention relates to cosmetic compositions comprising at least one wax having a melting point of 60.degree. to 110.degree. C., at least one cationic polymer having a molecular weight of between 1,000 and 3,000,000, at least one anionic polymer and ingredients normally used in cosmetics.
114 Sun protectant composition and method US635 1987-01-05 US4806344A 1989-02-21 Frances C. Gaskin
The invention relates to a composition and method of dissolving melanin in a composition for the purpose of photoprotection of the human epidermis from exposure to the sun's harmful rays. The composition consists of melanin, as an active ingredient, sunscreens, vitamins and emollients. These ingredients are rapid blended by ultrasound for 2-3 hours to form a mixture that enhances the sun protective factor when applied topically.
115 Hair conditioning preparation US644419 1984-08-27 US4753793A 1988-06-28 Ian B. Walton
There is disclosed a hair rinse conditioner which is capable of imparting a degree of set to the hair. The conditioner comprises, in an aqueous medium, a cationic surfactant which is present in lamellar phase and a latex of particles of a water-insoluble film-forming polymer, which latex has a minimum film-forming temperature in the range 15.degree. C. to 50.degree. C.
116 Pigmented detergents US389746 1973-08-20 US3956163A 1976-05-11 Do Ik Lee
Pigmented detergents having improved shelf stability are provided by dispersing in liquid detergent a polymeric pigment made by an emulsion polymerization process comprising the steps of (1) emulsion polymerizing from about 0 to about 80 weight percent of total monomer in absence of emulsifier, (2) adding a nonionic surfactant, and (3) continuing emulsion polymerization of the remaining monomer charge.
117 Conditioning shampoo containing a water-insoluble hair cosmetic agent US382440 1973-07-25 US3950510A 1976-04-13 Geoffrey Philip Adams
A shampoo which imparts various cosmetic attributes to the hair, ranging from gloss and condition to body and manageability comprises an aqueous solution of a surfactant and a hair cosmetic agent, for example a wood rosin or a polyketone resin maintained in dispersion in the solution by means of a thickening and suspending agent. On dilution of the shampoo with water during shampooing, the hair cosmetic agent is deposited onto the hair.
118 Oxygen-generating composition US21041038 1938-05-27 US2170052A 1939-08-22 LEIB HEIM MOSES; KARL FIEDLER
119 Method of and means for removing hair US69664133 1933-11-04 US2067909A 1937-01-19 KEMLER FLORENCE A
120 Detergent composition of matter US43416030 1930-03-07 US1921676A 1933-08-08 KAHN MAXWELL M
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