161 |
Improved medicine |
US68051D |
|
US68051A |
1867-08-27 |
|
|
162 |
Method of counteracting harmful effects of histamine |
US542427 |
2000-04-04 |
US6156318A |
2000-12-05 |
Minoru Sato; Masaaki Takeuchi; Naohiko Sato |
Harmful effects of histamine are counteracted by the administration of an antihistaminic substance comprising a water extract of a plant tissue of Stevia. Standing of the extract naturally cause fermentation to form one or more organic acids, such as lactic acid and acetic acid, thereby enhancing the antihistaminic action. The addition of at least one organic acid to the extract immediately after extraction can also enhance the antihistaminic action. |
163 |
Composition for cosmetic, pharmaceutical or dietetic use based on an
amino sugar and/or a polyhydroxylic acid |
US971436 |
1997-11-17 |
US6147054A |
2000-11-14 |
Gianfranco De Paoli Ambrosi |
A composition for cosmetic, pharmaceutical or dietetic use and including as the active ingredient, at least one of the substances which include acetylglucosamine and glucuronic acid in combination with the active ingredients which belong to the chemical class of the carboxylic acids, .alpha.-hydroxy acids, vitamins, amino acids, and bioflavonoids, and formulated with particular synergists, additives, and excipients for external use or for internal use. |
164 |
Breviscapinum and extracting process thereof from erigeron breviscapus |
US232082 |
1999-01-15 |
US6084080A |
2000-07-04 |
Lipin Zeng; De Pu |
An extracting process for extracting breviscapinum from erigeron breviscapus, wherein the breviscapinum has a chemical structure of 4',5,6-trishydroxyflavone-7-glucuronide that can increases cerebral blood flow for significantly decreasing cerebrovascular resistance; raises permeability of blood-brain barrier, increases nutritional blood flow of myocardium; raises immune function of body macrophage cell and counteraction against blood and oxygen depletion induced by hypophyseal pitutrin and thrombocyte agglutination induced by adenosine diphespate inhibiting internal thrombosis and promoting activity of cellulose dissolution; and increases peripheral and coronary bleed flow, effective for sequelas induced by cerebrovascular accident: palsy, coronary heart disease and angina pectoris. |
165 |
Galenic preparation for prevention and treatment of hepatocarcinoma |
US130488 |
1998-08-07 |
US6074648A |
2000-06-13 |
Jung Sik Lee |
The present invention relates to a galenic preparation for prevention and treatment of hepatocarcinoma. More specifically, the present invention relates to a galenic preparation which comprises an injectable composition having a good preventive and therapeutic effect particularly against hepatitis B virus and containing 4 kinds of main natural drugs, i.e., Hedyotidis herba, Curcumae longae rhizoma, Polygonati cuspidati radix and Sophorae tonkinesis radix; and an oral composition having a preventive and therapeutic effect against fatty liver and hepatic cirrhosis and containing 10 kinds of natural drugs, i.e., Hedyotidis herba, Paridis rhizoma, Polygoni cuspidati radix, Sophorae tonkinesis radix, Gentianae scabrae radix, Rhei rhizoma, Forsythiae fructus, Paeoniae radix rubra, Curcumae longae rhizoma and Acori graminei rhizoma, and which can effectively prevent the development of hepatic diseases including hepatitis, fatty liver and hepatic cirrhosis into hepatocarcinoma and treat hepatocarcinoma by combined administration of two kinds of the compositions. |
166 |
Dietary supplement for supporting cerebrovascular tone and treating
migraine headaches |
US104862 |
1998-06-25 |
US6068999A |
2000-05-30 |
Curt Hendrix |
The present invention relates to a dietary supplement for the support of normal cerebrovascular tone. Extracts of the feverfew plant in combination with magnesium and riboflavin, either singly or in combination provide the major therapeutic enhancement in the reduction of migraine headaches and the associated symptoms. |
167 |
Processing for preventing precipitates in fresh pressed echinacea juices |
US136670 |
1998-08-19 |
US6019977A |
2000-02-01 |
Heinz Walter Joseph |
A process for preventing precipitates in fresh pressed echinacea plant juice comprising cooling the fresh pressed plant juice obtained for a short time, followed by filtration and stabilisation by the addition of acid. The pressed plant juice is preferably cooled to temperatures between 0 and -15.degree. C. for less than 14 days and after filtration adjusted to a pH value below 6 by adding 0.01 to 5% of a polyvalent carboxylic acid, preferably citric acid. |
168 |
Nontoxic extract of larrea tridentata and method of making the same |
US152055 |
1998-09-11 |
US6004559A |
1999-12-21 |
Robert A. Sinnott; W. Dennis Clark; Kenneth Frank DeBoer |
A nontoxic, therapeutic agent having pharmacological activity comprising concentrated extract of Larrea tridentata plant material and ascorbic acid, an ascorbic acid ester, an ascorbic acid salt, butylated hydroxyanisole, butylated hydroxytoluene, hydrogen sulfide, hypophosphorous acid, monothioglycerol, potassium bisulfite, propyl gallate, sodium bisulfite, sodium hydrosulfite, sodium thiosulfate, sulfur dioxide, sulfurous acid, a tocopherol, or vitamin E is made by a process in which the plant material is extracted using an organic solvent, preferably acetone, and is then saturated with one of the listed reducing agents acid to reduce the toxic NDGA quinone, which naturally occurs in the plant material, to NDGA itself. Additional amounts of ascorbic acid, an ascorbic acid ester, an ascorbic acid salt, butylated hydroxyanisole, butylated hydroxytoluene, hydrogen sulfide, hypophosphorous acid, monothioglycerol, potassium bisulfite, propyl gallate, sodium bisulfite, sodium hydrosulfite, sodium thiosulfate, sulfur dioxide, sulfurous acid, a tocopherol, or vitamin E may be added to the extract to inhibit the natural oxidation of the NDGA into the toxic NDGA quinone in vivo, or during processing or storage. The resulting extract is useful in the treatment of viral diseases caused by viruses from the Herpesviridae family or viruses which require the Sp1 class of proteins to initiate viral replications. The resulting compound can also be used as an anti-inflammatory when the inflammatory diseases are mediated by the effects of leukotrienes. The listed reducing agents can also be used to stabilize NDGA as a therapeutic agent or a food additive. |
169 |
Insect repellent composition and method for inhibiting the transmission
and treatment of symptoms of vector-borne diseases |
US192421 |
1998-11-16 |
US5965137A |
1999-10-12 |
Edward J. Petrus |
A topical composition for the delivery of bio-affecting agents through the protective outer layer of skin into the underlying tissues and into the general circulation to prevent the causes and symptoms of vector-borne diseases. The transdermal penetration is achieved by the use of an essential volatile oil with insect repellent capabilities, such as eucalyptus oil. The bio-affective agents may be a combination of a zinc salt and form of vitamin A. A zinc salt may also be used for photoprotective purposes. The topical composition can be formulated as a solution, suspension, cream, ointment, gel, film or spray. |
170 |
Use of benzoin gum to inhibit P-glycoprotein-mediated resistance of
pharmaceutical compounds |
US973593 |
1998-02-11 |
US5916566A |
1999-06-29 |
Leslie Z. Benet; Vincent J. Wacher; Reed M. Benet |
A method for increasing bioavailabilty of an orally administered hydrophobic pharmaceutical compound, which comprises orally administering the pharmaceutical compound to a mammal in need of treatment with the compound concurrently with an essential oil or essential oil component in an amount sufficient to provide bioavailability of the compound in the presence of the essential oil or essential oil component greater than bioavailability of the compound in the absence of the essential oil or essential oil component, wherein the essential oil or essential oil component has an activity of at least 10% inhibition at a concentration 0.01 wt. % or less in an assay that measures reduced conversion of cyclosporine to hydroxylated products using an assay system containing 250 .mu.g rat liver microsomes, 1 .mu.M cyclosporine, and 1 .mu.M reduced nicotinamide adenine dinucleotide phosphate (NADPH) in 1 ml of 0.1 M sodium phosphate buffer, pH 7.4. |
171 |
Pharmaceutical compositions containing flavanolignanes and methods for
using same as an antiproliferative |
US952415 |
1997-11-18 |
US5912265A |
1999-06-15 |
Ezio Bombardelli; Paolo Morazzoni |
The invention relates to methods for preventing, inhibiting, or suppressing tumors by administering to a person in need of such treatment a therapeutically effective amount of one or more flavanolignanes, such as silymarin, silybin, silidianin, silicristin, dehydrosilybin, mixtures thereof, or extracts thereof as an antiproliferative. The invention further relates to the antitumor pharmaceutical composition includes a therapeutically effective amount of the flavanolignane selected from the group of silymarin, silybin, silidianin, silicristin, dehydrosilybin, and mixtures thereof, in combination with a different antitumor agent. In another embodiment, the pharmaceutical composition includes a therapeutically effective amount of a flavanolignane selected from the group of silidianin, silicristin, and mixtures thereof, with a pharmaceutically acceptable carrier or excipient. The compositions and method may be prepared or administered with different antitumoral agents for concurrent or sequential use for treating tumors, such as those typically found in the uterus, ovary, and breast. |
172 |
Compositions with analgesic, antipyretic and antiinflammatory properties |
US70240 |
1998-05-01 |
US5908628A |
1999-06-01 |
Liping Hou |
The present invention provides compositions comprising talc, silkworm excrement, and ingredients of plants of species of the genera Stephania, Coix, Pinellia, Prunus, Phellodendron, Sophora, Tetrapanax, Stemona, Glycyrrhiza, Tripterygium, Forsythia and Siegesbeckia, wherein such compositions have analgesic, antipyretic, and antiinflammatory properties. The present invention also provides methods of using such compositions for treating various diseases, including osteoarthritis and rheumatoid arthritis. |
173 |
Camomile oils having a high natural poly-ynes content and process for
their production |
US908856 |
1992-07-01 |
US5902587A |
1999-05-11 |
Reinhold Carle; Otto Isaac |
Camomile oil having a high cis- and trans-spiroether content is produced in a process which includes steam distillation or aqueous distillation of fresh camomile or an extraction residue of camomile. |
174 |
Internal breath freshener and digestive aid |
US869693 |
1997-06-05 |
US5900251A |
1999-05-04 |
Anthony Raissen |
An essentially herbal or herbal extract composition for the treatment and control of breath odors and aiding digestion, and method of treatment or control of breath odors and aiding digestion therewith. The preferred composition contains ginger, licorice, chamomile, parsley seed oil, and sunflower seed oil in a delivery system which is intended to be ingested and swallowed whole for delivery of the ingredients to the stomach and/or lower in the digestive tract. |
175 |
Compositions and methods for the control of smoking |
US809400 |
1997-03-21 |
US5883137A |
1999-03-16 |
Michael Glenn King |
Compositions and methods for the control of smoking are described. The compositions according to the invention comprise: (a) a xanthine oxidase inhibitor; (b) a cytochrome P450 inhibitor; (c) a sugar; (d) a source of phosphate; and, optionally, (e) one or more pharmaceutically acceptable excipients. |
176 |
Pain reliever and method of use |
US870261 |
1997-06-06 |
US5856361A |
1999-01-05 |
Stephen D. Holt; Timothy R. Laughlin |
A composition containing capsaicin together with another ingredient to neutralize the discomfort resulting from the application of capsaicin to the skin can be used to treat many types of discomforts, including musculo-skeletal pain, neuralgia and neurpathies, without the discomfort normally associated with the topical application of capsaicin. |
177 |
Use of an extract from a non-photosynthetic filamentous bacterium and
composition containing it |
US711109 |
1996-09-09 |
US5795574A |
1998-08-18 |
Lionel Breton; Lucien Aubert; Jacques Leclaire; Richard Martin; Olivier De Lacharriere |
The present invention relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium as substance P antagonist in a cosmetic composition or for the preparation of a pharmaceutical composition. The invention also relates to the use of at least one extract from at least one non-photosynthetic filamentous bacterium in a cosmetic composition or for the preparation of a pharmaceutical composition intended for the treatment of disorders associated with an excess in the synthesis and/or in the release of substance P. The invention additionally relates to various compositions containing an extract from at least one non-photosynthetic filamentous bacterium and to a cosmetic treatment process. |
178 |
Homeopathic pharmaceutical compositions |
US004573 |
1998-01-08 |
US5795573A |
1998-08-18 |
Lou Paradise |
A homeopathic topical anti-inflammatory and pain relieving composition containing an effective amount of the combination of Arnica Montana, Rhus toxicodendron and Aesculus hippocastanum together with belladonna in the form of a lotion, cream or gel. |
179 |
Active oxygen free radical scavenging agent |
US367277 |
1995-01-11 |
US5788971A |
1998-08-04 |
Keiichi Togasaki |
An active oxygen free radical scavenging agent superior in scavenging active oxygen free radicals produced in organisms is provided. The active oxygen free radical extinguishing agent includes green tea leaf extract containing epigallo catechin gallate and sunflower seed extract containing chlorogenic acid. When administrating green tea leaf extract and sunflower seed extract simultaneously as disclosed in the embodiment, the active oxygen free radical scavenging effect greatly excels the same when said two kinds of active oxygen free radical scavenging agents are separately administrated as shown in reference 2 and reference 3, or the same when rhubarb is administrated as shown in reference 4. |
180 |
Colloidal silver, honey, and helichrysum oil antiseptic composition and
method of application |
US781460 |
1997-01-10 |
US5785972A |
1998-07-28 |
Kathleen A. Tyler |
A composition of matter comprising a therapeutically active compound with antiseptic and osmotic characteristics for treatment or therapy for burns and open wounds experienced by animals and man and in particular to the treatment of thermal burns on humans by use of spray, mist, dropper or saturated bandage application of the solution disclosed. The compound in solution form composed of colloidal silver, helichrysum angustifolium or helichrysum italicum oil and raw honey emulsified with water soluble lecithin by agitation. |