序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
141 Utero-evacuant extracts from plant substances US690765 1976-05-27 US4076805A 1978-02-28 Jose Luis Mateos; Luis Noriega; Richard E. Huettemann; Ramesh M. Kanojia
A method of purifying utero-evacuant extracts from the zoapatle plant is described. The method involves the purification of extracts from the zoapatle plant which contain an active principle utilizing chromatographic techniques.
142 Hypoglycemic composition and method of use US578941 1975-05-20 US3950518A 1976-04-13 Carlton E. Turner; John C. Craig, Jr.
A compound prepared from the extract of Xanthium strumarium (cockleburr) characterized by being a white crystalline glycoside having a decomposition point of 278.degree.-279.degree.C.; a molecular formula of C.sub.31 H.sub.48 O.sub.24 S.sub.2, the aglycone portion of the molecule having a molecular formula of C.sub.19 H.sub.28 O.sub.4 ; substantially no ultraviolet absorption above 200 m.mu.; infrared spectrum showing hydrogen bonded OH absorption, 3440 cm.sup.-.sup.1 ; C--H stretch, 2940 cm.sup.-.sup.1 ; carbonyl stretch, 1735 cm.sup.-.sup.1 ; C--O stretch, 1250 cm.sup.-.sup.1 ; and other absorptions at 1640; 1460; 1380; 1040; 1000; 900; and 800 cm.sup.-.sup.1 ; a nuclear magnetic resonance spectrum in deuterium oxide showing a broad absorption at 304, 230, 162, 134, 92 and 58 cps relative to external tetramethylsilane standard; and the mass spectrum of the silylated derivative gives a mass fragment of 952 amu. Hypoglycemic compositions consisting essentially of the foregoing described compound prepared from cockleburrs in admixture with a non-toxic, pharmaceutically-acceptable carrier. A method of reducing blood sugar levels in animals comprising administering a therapeutically effective concentration of the inventive compound in a pharmaceutically suitable carrier intravenously, orally, intraperitoneally and intramuscularly. The method of preparing a hypoglycemic pharmacologically active therapeutic compound from cockleburrs (Xanthium strumarium).
143 Hypoglycemic compound and method of preparing US53334774 1974-12-16 US3922263A 1975-11-25 TURNER CARLTON E; CRAIG JR JOHN C
A compound prepared from the extract of Xanthium strumarium (cockleburr) characterized by being a white crystalline glycoside having a decomposition point of 278*-279*C.; a molecular formula of C31H48O24S2, the aglycone portion of the molecule having a molecular formula of C19H28O4; substantially no ultraviolet absorption above 200 m Mu ; infrared spectrum showing hydrogen bonded OH absorption, 3440 cm 1; C-H stretch, 2940 cm 1; carbonyl stretch, 1735 cm 1; C-O stretch, 1250 cm 1; and other absorptions at 1640; 1460; 1380; 1040; 1000; 900; and 800 cm 1; a nuclear magnetic resonance spectrum in deuterium oxide showing a broad absorption at 304, 230, 162, 134, 92 and 58 cps relative to external tetramethylsilane standard; and the mass spectrum of the silylated derivative gives a mass fragment of 952 amu. Hypoglycemic compositions consisting essentially of the foregoing described compound prepared from cockleburrs in admixture with a non-toxic, pharmaceutically-acceptable carrier. A method of reducing blood sugar levels in animals comprising administering a therapeutically effective concentration of the inventive compound in a pharmaceutically suitable carrier intravenously, orally, intraperitoneally and intramuscularly. The method of preparing a hypoglycemic pharmacologically active therapeutic compound from cockleburrs (Xanthium strumarium).
144 Process for obtaining an extract of arnica montana US29082672 1972-09-21 US3832343A 1974-08-27 MAJOIE B
THE INVENTION PROVIDES A PROCESS FOR EXTRACTING ARNICA MONTANA, IN WICH THE PLANT IS EXTRACTED WITH AT LEAST ONE SOLVENT CHOSEN FROM PETROLEUM ETHER, DIETHYL ETHER, ACETONE, CCLOROFRM, ETHANOL, WATER AND THEIR MIXTURES, THE RESULTING FILTRATE OR FILTRATES ARE TREATED WITH METHANOL, AND POLAR SUBSTANCES ARE REMOVED BY FILTRATION AFTER TREATMENT OF THE SOLUTION OBTAINED WITH ETHYL ACETATE. THE EXTRACT SO OBTAINED HAS ACITVITY IN PREVENTING THE COAGULATION OF BLOOD.
145 Extraction of pyrethrum US21884262 1962-08-23 US3243451A 1966-03-29 JULIUS WARD
146 Therapeutic d-ortho-menthatriene 1 (7), 5, 8-ol-3 US4250060 1960-07-13 US3112245A 1963-11-26 YVES-RENE NAVES; FERNAND CAUJOLLE
147 Process for extraction of oil soluble growth substances and hormones from flowering plants and resulting compositions US41446754 1954-03-05 US2937206A 1960-05-17 ROBERTS RAY H; STRUCKMEYER BURDEAN E
148 Sealing wounds and method of US2039082D US2039082A 1936-04-28
149 Powdered preparation for poultices US68040523 1923-12-13 US1519755A 1924-12-16 CHAPMAN FRANK F B
150 Process for manufacturing surgical dressings. US22557418 1918-03-29 US1268076A 1918-05-28 HOLLIDAY KARL J
151 Insecticide US593089D US593089A 1897-11-02
152 Mlian zinglee US281521D US281521A 1883-07-17
153 Hog-cholera compound US244643D US244643A 1881-07-19
154 Improvement in medical compounds US155581D US155581A 1874-10-06
155 Improved wt for burns, scalds US101340D US101340A 1870-03-29
156 Winiua j US96437D US96437A 1869-11-02
157 Improved troche US96324D US96324A 1869-11-02
158 Improved medical plaster US83872D US83872A 1868-11-10
159 Improved oathaetio igzenge US79641D US79641A 1868-07-07
160 William h US68582D US68582A 1867-09-03
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