专利检索_ ..铋专利检索_ ..铋专利检索查询

序号	专利名	申请号	申请日	公开（公告）号	公开（公告）日	发明人
1	PRODUCTION OF ISOTOPES USING HIGH POWER PROTON BEAMS	US14949665	2015-11-23	US20160111176A1	2016-04-21	Jerry A. Nolen, JR.; Itacil C. Gomes
The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope 225Ac is produced via the nuclear reaction (p,2p6n),whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a 232Th target nucleus. Another medically important isotope 213Bi is then available as a decay product. The production of highly purified 211At is also provided.
2	Production of isotopes using high power proton beams	US13025079	2011-02-10	US09202602B2	2015-12-01	Jerry A. Nolen, Jr.; Itacil C. Gomes
The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope 225Ac is produced via the nuclear reaction (p,2p6n), whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a 232Th target nucleus. Another medically important isotope 213Bi is then available as a decay product. The production of highly purified 211At is also provided.
3	The manufacturing method and apparatus of Bi-212 and uses thereof	JP51183298	1997-08-26	JP2000505097A	2000-04-25	ポールヴィーハーパー; ジョンジェイハインズ; ジェニーエルホワイトロック; ジェイコブロートメンシュ
(57)【要約】実質的に放射性不純物を含まないBi-212の製造方法が開示される。 Pb-212を含む供給酸性溶液を抽出媒体と接触させてそれに該Pb-212を結合させる。該抽出媒体を第２酸性溶液で洗浄して不純物を除去し、実質的に不純物を含まないPb-212担持抽出媒体を得る。該Pb-212が該抽出媒体上で成長して放射性壊変によりBi-212を生成する。次に、該抽出媒体から酸性溶液で該Bi-212を溶離して実質的に放射性不純物を含まないBi-212酸性溶液を生成する。本方法を行う装置及びその治療方法も開示される。
4	PROCESS AND APPARATUS FOR THE PRODUCTION OF Bi-212 AND A USE THEREOF	EP97940622.0	1997-08-26	EP0979513A1	2000-02-16	ROTMENSCH, Jacob; WHITLOCK, Jenny, L.; HINES, John, J.; HARPER, Paul, V.
A process for producing substantially radio-impurity-free Bi-212 is disclosed. An acidic feed solution containing Pb-212 is contacted with an extraction medium to bind the Pb-212 thereto. The extraction medium is rinsed with a second acid solution to remove impurities therefrom, leaving a substantially impurity-free Pb-212-laden extraction medium. The Pb-212 grows on the extraction medium to form Bi-212 by radioactive decay. The Bi-212 is then eluted from the extraction medium with an acid solution to form a substantially radio-impurity-free Bi-212 acid solution. An apparatus for carrying out this process and a process for the therapeutic use thereof are also disclosed.
5	PROCESS AND APPARATUS FOR THE PRODUCTION OF Bi-212 AND A USE THEREOF	EP97940622	1997-08-26	EP0979513A4	2002-04-10	ROTMENSCH JACOB; WHITLOCK JENNY L; HINES JOHN J; HARPER PAUL V
PCT No. PCT/US97/14994 Sec. 371 Date Jan. 28, 1999 Sec. 102(e) Date Jan. 28, 1999 PCT Filed Aug. 26, 1997 PCT Pub. No. WO98/08481 PCT Pub. Date Mar. 5, 1998A process for producing substantially radio-impurity-free Bi-212 is disclosed. An acidic feed solution containing Pb-212 is contacted with an extraction medium to bind the Pb-212 thereto. The extraction medium is rinsed with a second acid solution to remove impurities therefrom, leaving a substantially impurity-free Pb-212-laden extraction medium The Pb-212 grows on the extraction medium to form Bi-212 by radioactive decay. The Bi-212 is then eluted from the extraction medium with an acid solution to form a substantially radio-impurity-free Bi-212 acid solution. An apparatus for carving out this process and a process for the therapeutic use thereof are also disclosed.
6	SYSTEM, EMANATION GENERATOR, AND PROCESS FOR PRODUCTION OF HIGH-PURITY THERAPEUTIC RADIOISOTOPES	US15675529	2017-08-11	US20180047474A1	2018-02-15	Matthew J. O'Hara
An isotope production system, emanation generator, and process are disclosed for production of high-purity radioisotopes. In one implementation example, high-purity Pb-212 and/or Bi-212 isotopes are produced suitable for therapeutic applications. In one embodiment the process includes transporting gaseous radon-220 from a radium-224 bearing generator which provides gas-phase separation of the Rn-220 from the Ra-224 in the generator. Subsequent decay of the captured Rn-220 accumulates high-purity Pb-212 and/or Bi-212 isotopes suitable for direct therapeutic applications. Other high-purity product isotopes may also be prepared.
7	METHOD OF PRE-TREATING AN ADSORBENT FOR A CHROMATOGRAPHIC SEPARATION	US13707824	2012-12-07	US20130220928A1	2013-08-29	Steve OELSNER
A method of treating an adsorbent for a chromatographic separation. The method involves sonicating particles of an inorganic metal oxide having fragile edges in the absence of any alkylating or acylating agent to form smoothened particles of the inorganic metal oxide and washing the smoothened particles of the inorganic metal oxide to remove fine particulate matter to produce a treated adsorbent. The treated adsorbent can be used in a method of isolating a daughter radioisotope from a daughter radioisotope that is produced from the parent radioisotope by radioactive decay.
8	PRODUCTION OF ISOTOPES USING HIGH POWER PROTON BEAMS	US13025079	2011-02-10	US20110200154A1	2011-08-18	Jerry A. Nolen, JR.; Itacil C. Gomes
The invention provides for a method for producing isotopes using a beam of particles from an accelerator, whereby the beam is maintained at between about 70 to 2000 MeV; and contacting a thorium-containing target with the particles. The medically important isotope 225Ac is produced via the nuclear reaction (p,2p6n), whereby an energetic proton causes the ejection of 2 protons and 6 neutrons from a 232Th target nucleus. Another medically important isotope 213Bi is then available as a decay product. The production of highly purified 211At is also provided.
9	Process and apparatus for the production of BI-212 and a use thereof	US230635	1999-01-28	US6126909A	2000-10-03	Jacob Rotmensch; Jenny L. Whitlock; John J. Hines; Paul V. Harper
A process for producing substantially radio-impurity-free Bi-212 is disclosed. An acidic feed solution containing Pb-212 is contacted with an extraction medium to bind the Pb-212 thereto. The extraction medium is rinsed with a second acid solution to remove impurities therefrom, leaving a substantially impurity-free Pb-212-laden extraction medium The Pb-212 grows on the extraction medium to form Bi-212 by radioactive decay. The Bi-212 is then eluted from the extraction medium with an acid solution to form a substantially radio-impurity-free Bi-212 acid solution. An apparatus for carving out this process and a process for the therapeutic use thereof are also disclosed.
10	PROCESS AND APPARATUS FOR THE PRODUCTION OF BI-212 AND A USE THEREOF	PCT/US9714994	1997-08-26	WO9808481A3	1999-03-18	ROTMENSCH JACOB; WHITLOCK JENNY L; HINES JOHN J; HARPER PAUL V
PCT No. PCT/US97/14994 Sec. 371 Date Jan. 28, 1999 Sec. 102(e) Date Jan. 28, 1999 PCT Filed Aug. 26, 1997 PCT Pub. No. WO98/08481 PCT Pub. Date Mar. 5, 1998A process for producing substantially radio-impurity-free Bi-212 is disclosed. An acidic feed solution containing Pb-212 is contacted with an extraction medium to bind the Pb-212 thereto. The extraction medium is rinsed with a second acid solution to remove impurities therefrom, leaving a substantially impurity-free Pb-212-laden extraction medium The Pb-212 grows on the extraction medium to form Bi-212 by radioactive decay. The Bi-212 is then eluted from the extraction medium with an acid solution to form a substantially radio-impurity-free Bi-212 acid solution. An apparatus for carving out this process and a process for the therapeutic use thereof are also disclosed.

该功能需要专业版企业版VIP权限，您可以：