| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | Production of selenium-72 and arsenic-72 | US9250 | 1993-01-25 | US5371372A | 1994-12-06 | Dennis R. Phillips |
| Methods and apparatus for producing selenium-72, separating it from its daughter isotope arsenic-72, and generating multiple portions of a solution containing arsenic-72 from a reusable parent substance comprised of selenium-72. The invention provides apparatus which can be located at a site where arsenic-72 is used, for purposes such as PET imaging, to produce arsenic-72 as needed, since the half-life of arsenic-72 is very short. | ||||||
| 2 | Production of selenium-72 and arsenic-72 | US756022 | 1991-09-06 | US5204072A | 1993-04-20 | Dennis R. Phillips |
| Methods for producing selenium-72, separating it from its daughter isotope arsenic-72, and generating multiple portions of a solution containing arsenic-72 from a reusable parent substance comprised of selenium-72. | ||||||
| 3 | Production of selenium-72 and arsenic-72 | US297459 | 1994-08-29 | US5405589A | 1995-04-11 | Dennis R. Phillips |
| Methods and apparatus for producing selenium-72, separating it from its daughter isotope arsenic-72, and generating multiple portions of a solution containing arsenic-72 from a reusable parent substance comprised of selenium-72. The invention provides apparatus which can be located at a site where arsenic-72 is used, for purposes such as PET imaging, to produce arsenic-72 as needed, since the half-life of arsenic-72 is very short. | ||||||
| 4 | PRODUCTION OF SELENIUM-72 AND ARSENIC-72. | EP92919525 | 1992-09-04 | EP0604505A4 | 1994-04-27 | PHILLIPS DENNIS RAY |
| Methods and apparatus for producing selenium-72, separating it from its daughter isotope arsenic-72, and generating multiple portions of a solution containing arsenic-72 from a reusable parent substance comprised of selenium-72. The invention provides apparatus which can be located at a site where arsenic-72 is used, for purposes such as PET imaging, to produce arsenic-72 as needed, since the half-life of arsenic-72 is very short. A solution containing arsenic-72 is placed into reactor (100). Hydrazine dihydrochloride and a carrier comprised of selenium are added through additive funnel (103) and conduit (102). The contents of reactor (100) are heated by electrical heating jacket (106). After reaction, the material in reactor (100) is passed to separation means (101), where the solution containing As-72 is separated from the solid comprised of Se-72. The solution is returned to reactor (100) by means of conduit (112). Product solution is treated to remove hydrazinium ion and then removed from reactor (100) by means of conduit (110). An HCl/H2O2 solution is then heated in reactor (100) and circulated through filter means (101) in order to dissolve the precipitated Se. This solution is removed through conduit (110) and is stored to allow As-72 to grow-in and H2O2 to decompose. | ||||||
| 5 | Sorbent for receiving radionuclide arsenic-72, production of this sorbent and its use | EP12152024.1 | 2012-01-22 | EP2618335A1 | 2013-07-24 | Polkowska-Motrenko, Halina; Bilewicz, Aleksander; Doner, Katarzyna; Chajduk, Ewelina |
According to the invention, the method of obtaining arsenic-72 radionuclide from selenium-72 radionuclide, consists in separating arsenic radionuclide from selenium radionuclide by the means of extraction chromatography, using hydrophobic styrene-divinylbenzene copolymers, especially Amberlite XAD-4 or Bio-Beads SM-2 carriers, with embedded substance, from the group of aromatic ortho-diamines, favourably 3,3' diaminobenzidine or 2,3 naphthalenediamine. |
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| 6 | Sorbent for receiving radionuclide arsenic-72, production of this sorbent and its use | EP12152024.1 | 2012-01-22 | EP2618335B1 | 2014-12-17 | Polkowska-Motrenko, Halina; Bilewicz, Aleksander; Doner, Katarzyna; Chajduk, Ewelina |
| 7 | PRODUCTION OF SELENIUM-72 AND ARSENIC-72 | EP92919525.0 | 1992-09-04 | EP0604505A1 | 1994-07-06 | PHILLIPS, Dennis, Ray |
| Procédé et dispositif servant à produire du sélénium-72, à le séparer de l'arsenic-72, son isotope de filiation, et à générer des quantités multiples d'une solution contenant l'arsenic-72 à partir d'une substance mère réutilisable constituée par le sélénium-72. L'invention décrit un dispositif pouvant se trouver dans des installations où on utilise de l'arsenic-72, par exemple, dans une installation de tomographie par émission de positrons (PET), de façon à produire ledit arsenic-72 en fonction des nécessités, étant donné que la période radioactive dudit arsenic-72 est très courte. On place une solution contenant de l'arsenic-72 dans un réacteur (100). On ajoute du dihydrochlorure d'hydrazine et un véhicule constitué par du sélénium à travers l'entonnoir d'apport (103) et le conduit (102). Les contenus dudit réacteur (100) sont réchauffés par une chemise de réchauffement électrique (106). Après la réaction, le matériau situé dans le réacteur (100) passe dans un moyen de séparation (101), où la solution contenant de l'As-72 est séparée du solide constitué par le Se-72. On renvoie la solution au réacteur (100) au moyen du conduit (112). On traite la solution obtenue, de façon à supprimer les ions d'hydrazinium et on l'enlève ensuite du réacteur (100) au moyen du conduit (110). On réchauffe ensuite une solution de HCl/H2O2 dans le réacteur (100) et on la fait circuler par le filtre (101), de façon à dissoudre le sélénium précipité. On évacue la solution par le conduit (110) et on la stocke, de façon à permettre la croissance de As-72 et la décomposition de H2O2. | ||||||
