| 序号 | 专利名 | 申请号 | 申请日 | 公开（公告）号 | 公开（公告）日 | 发明人 |
|---|---|---|---|---|---|---|
| 1 | 一种用于放射性同位素生产系统的靶设备 | CN201280029863.0 | 2012-06-13 | CN103621189B | 2016-09-14 | J.诺尔林; T.埃里克松 |
| 本发明提供一种用于放射性同位素生产系统的靶设备。所述靶设备包括生产室，所述生产室配置成容纳启动液体。所述生产室配置成接纳粒子束，所述粒子束入射到所述启动液体上，从而产生放射性同位素并且将所述启动液体的一部分转换成蒸汽。所述靶设备还包括冷凝室和流体通道，所述流体通道将所述生产室和冷凝室流体连通，并且配置成允许所述蒸汽从所述生产室流动到所述冷凝室。所述冷凝室配置成将所述蒸汽转换成冷凝液体。 | ||||||
| 2 | 电化学电池和用于在电极上分离来自溶液的无载流子的18F-的方法 | CN201080024005.8 | 2010-04-17 | CN102449706A | 2012-05-09 | K.哈马歇 |
| 本发明涉及电化学电池以及用于将无载流子的放射性核从溶液中分离到电极上的方法。根据本发明，18F-在电化学电池中从水溶液中沉积到被金刚石化的阳极（1）上。接着抽干该电化学电池并且用具有转移催化剂的液体涂层，优选地阳极连接为阴极并且18F-被转移到液体相。 | ||||||
| 3 | 一种用于放射性同位素生产系统的靶设备 | CN201280029863.0 | 2012-06-13 | CN103621189A | 2014-03-05 | J.诺尔林; T.埃里克松 |
| 本发明提供一种用于放射性同位素生产系统的靶设备。所述靶设备包括生产室，所述生产室配置成容纳启动液体。所述生产室配置成接纳粒子束，所述粒子束入射到所述启动液体上，从而产生放射性同位素并且将所述启动液体的一部分转换成蒸汽。所述靶设备还包括冷凝室和流体通道，所述流体通道将所述生产室和冷凝室流体连通，并且配置成允许所述蒸汽从所述生产室流动到所述冷凝室。所述冷凝室配置成将所述蒸汽转换成冷凝液体。 | ||||||
| 4 | 放射性药物制造和装置 | CN201180068484.8 | 2011-12-22 | CN103380058A | 2013-10-30 | C.斯蒂尔; S.K.卢思拉; R.富特; F.沙 |
| 一种用于PET放射性药物制造的构件和系统包括用于放射性同位素筒的运输防护件、用于从运输防护件进行分配的盒、用于盒的盒合成平台，以及合成器防护件。 | ||||||
| 5 | Electrochemical phase transfer device and method | JP2012519803 | 2010-07-12 | JP2012533070A | 2012-12-20 | ボーラー，マルコ; サンパー，ビクター; レンシュ，クリスティアン; ボールド，クリストフ |
| 電気化学的相間移動用のデバイス及び方法は、ガラス状炭素又は炭素とポリマーとの複合材料から形成される１以上の電極を利用する。 本デバイスは、入口４２、出口４４、及びそれらの間に延在する細長い流体通路３６を画成するデバイス筐体を含む。 捕集電極１２及び対電極は、流体通路が捕集電極と対電極との間に延在するように筐体内に配置される。
【選択図】 図１ |
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| 6 | フローセル、放射性フッ素アニオン濃縮装置及び放射性フッ素アニオン濃縮方法 | JP2009529942 | 2007-08-31 | JPWO2009028093A1 | 2010-11-25 | 中西 博昭; 博昭 中西; 小西 聡; 聡 小西; 圭介 中 |
| フローセル2は絶縁性の基板2a,2bにより構成されている。両基板2a,2bは例えば陽極接合やフッ酸接合など堅牢な接合方法により直接接合されている。基板2aと2bの対向面には流路6が形成されており、その流路6内で基板2a上には、ペースト状の炭素材料を焼結させてなる炭素電極4aが流路6に沿って形成されている。一方、基板2bにはその流路6をなす溝6aが形成され、その溝6aの底面に金属膜からなる電極4bが形成されている。 | ||||||
| 7 | Apparatus and method for the manufacture of 18f- fluoride by ion beam | JP2003504416 | 2002-06-13 | JP2005517151A | 2005-06-09 | ツァイスラー，シュテファン，ケイ．; バックリー，ケネス，アール．; ルース，トーマス，ジェイ． |
| 本発明は、気体状または液状の転換媒体に放射線照射する粒子ビームを用いて、 18 Ｆ−フッ化物を製造する装置および方法である。 照射された転換媒体は、生産された 18 Ｆ−フッ化物が結合するフッ化物吸着物質に取り囲まれたチェンバーに入っている。 上記物質に付着するフッ化物の吸着特性は、吸着の増加／減少要因により操作される。 チェンバーにある間、溶媒は、上記物質を吸着した 18 Ｆ−フッ化物から取り出した製造された 18 Ｆ−フッ化物を溶かす。 溶媒はそれから、 18 Ｆ−フッ化物を得るために、処理される。 | ||||||
| 8 | TARGET ASSEMBLY AND ISOTOPE PRODUCTION SYSTEM | US15348198 | 2016-11-10 | US20180130567A1 | 2018-05-10 | Tomas Eriksson; Martin Pärnaste; Jonas Norling |
| Target assembly for an isotope production system. The target assembly includes a target body having a production chamber and a beam cavity that is adjacent to the production chamber. The production chamber is configured to hold a target material. The beam cavity opens to an exterior of the target body and is configured to receive a particle beam that is incident on the production chamber. The target assembly also includes a target sheet positioned to separate the beam cavity and the production chamber. The target sheet has a side that is exposed to the production chamber such that the target sheet is in contact with the target material during isotope production. The target sheet includes graphene. | ||||||
| 9 | Target apparatus and isotope production systems and methods using the same | US13162941 | 2011-06-17 | US09336915B2 | 2016-05-10 | Jonas Norling; Tomas Eriksson |
| A target apparatus for a radioisotope production system. The target apparatus includes a production chamber that is configured to contain a starting liquid. The production chamber is configured to receive a particle beam that is incident upon the starting liquid thereby generating radioisotopes and transforming a portion of the starting liquid into vapor. The target apparatus also includes a condensing chamber and a fluid channel that fluidly couples the production and condensing chambers and is configured to allow the vapor to flow from the production chamber to the condensing chamber. The condensing chamber is configured to transform the vapor into a condensed liquid. | ||||||
| 10 | RADIOPHARMACY AND DEVICES | US13976106 | 2011-12-22 | US20130334443A1 | 2013-12-19 | Colin Steel; Sajinder Kaur Luthra; Robin Fortt; Farah Shah |
| Components and systems for a PET radiopharmacy include a transport shield for a radioisotope cartridge, a cassette for dispensing from a transport shield, a cassette synthesis platform for a cassette, and a synthesizer shield. | ||||||
| 11 | Device For Producing Radioisotopes | US13881305 | 2011-10-27 | US20130266105A1 | 2013-10-10 | Bernard Lambert; Jean-Michel Geets; Andrea Cambriani; Michel Degeyter; Maxim Kiselev |
| The invention relates to a device (1) for producing radioisotopes by irradiating a target fluid using a particle beam (13). This device comprises an irradiation cell (7) that includes a cavity (3) for receiving the target fluid. A non-cryogenic cooling device cools the walls of the cavity (3). The cavity (3) has an inclined surface (15) downwardly delimiting the cavity (3) so as to evacuate the target fluid, which condenses on contact with the cooled walls, under gravity towards a metal foil (4) which closes off this cavity (3). The inclined surface (15) intersects the plane formed by the metal foil (4), making an acute angle (a) with said plane, so as to form with the metal foil (4) a wedge-shaped zone (18) capable of collecting, by gravity, the condensed target fluid. | ||||||
| 12 | Flow cell, apparatus for concentrating radioactive fluoride anion, and method of concentrating radioactive fluoride anion | US12674001 | 2007-08-31 | US08491776B2 | 2013-07-23 | Hiroaki Nakanishi; Satoshi Konishi; Keisuke Naka |
| A flowcell 2 is constituted of insulating substrates 2a and 2b. The two substrates 2a and 2b have been directly bonded to each other by a bonding method for attaining tenacious bonding, for example, anodic bonding or hydrofluoric acid bonding. A channel 6 has been formed at the interface between the substrates 2a and 2b. Part of the substrate 2a which faces the channel 6 has a carbon electrode 4a formed thereon by sintering a pasty carbon material, the electrode 4a extending along the channel 6. On the other hand, the substrate 2b has a groove 6a serving as the channel 6, and has an electrode 4b made of a metal film formed on a bottom surface of the groove 6a. | ||||||
| 13 | TARGET APPARATUS AND ISOTOPE PRODUCTION SYSTEMS AND METHODS USING THE SAME | US13162941 | 2011-06-17 | US20120321026A1 | 2012-12-20 | JONAS NORLING; TOMAS ERIKSSON |
| A target apparatus for a radioisotope production system. The target apparatus includes a production chamber that is configured to contain a starting liquid. The production chamber is configured to receive a particle beam that is incident upon the starting liquid thereby generating radioisotopes and transforming a portion of the starting liquid into vapor. The target apparatus also includes a condensing chamber and a fluid channel that fluidly couples the production and condensing chambers and is configured to allow the vapor to flow from the production chamber to the condensing chamber. The condensing chamber is configured to transform the vapor into a condensed liquid. | ||||||
| 14 | ELECTROCHEMICAL PHASE TRANSFER DEVICES AND METHODS | US13377881 | 2010-07-12 | US20120145557A1 | 2012-06-14 | Marko Baller; Victor Samper; Christian Rensch; Christoph Boeld |
| Devices and methods for electrochemical phase transfer utilize at least one electrode formed from either glassy carbon or a carbon and polymer composite. The device includes a device housing defining an inlet port (42), an outlet port (44) and an elongate fluid passageway (36) extending therebetween. A capture electrode (12) and a counter electrode are positioned within said housing such that the fluid passageway extends between the capture and counter electrodes. | ||||||
| 15 | RADIOACTIVE FLUORINE ANION CONCENTRATING DEVICE AND METHOD | US12532957 | 2007-03-26 | US20100101943A1 | 2010-04-29 | Ren Iwata; Eiichi Ozeki; Hiroaki Nakanishi; Katsumasa Sakamoto; Ryo Yamahara |
| A radioactive fluoride anion concentrating device capable of concentrating 18F− ions speedily and efficiently. A flow cell (11) is composed of a metal plate electrode (21), an insulating sheet (23) and a carbon plate electrode (25) located so that the sides of electrodes may be opposed to each other with the insulating sheet (23) inserted between them. An example of the plate metal plate electrode (21) is obtained by forming a film of metallic material on an insulation plate, and an example of the insulating sheet (23) is a PDMS from which a groove being a channel (26) having a thickness of ≦500 μm is cut out. The thickness of the sheet is desirably about 100 μm. The upper and lower sides of the flow cell (11) are fixed by fixing jigs (27) and (29). | ||||||
| 16 | Apparatus for generating 18F-Fluoride by ion beams | US11000040 | 2004-12-01 | US20050201504A1 | 2005-09-15 | Stefan Zeisler; Kenneth Buckley; Thomas Ruth |
| An apparatus for producing 18F-Fluoride by using a particle beam to irradiate conversion medium in gaseous or liquid form. The irradiated conversion medium is contained in a chamber surrounded by a Fluoride adsorbing material to which the produced 18F-Fluoride adheres. The adsorption properties of the Fluoride adsorbing material are manipulated by an adsorption enhancing/decreasing element. A solvent dissolves the produced 18F-Fluoride off of the Fluoride adsorbing material while it is in the chamber. The solvent is then processed to obtain the 18F-Fluoride. | ||||||
| 17 | System and method for the production of 18F-Fluoride | US09790572 | 2001-02-23 | US20010043663A1 | 2001-11-22 | Thomas J. Ruth; Kenneth R. Buckley; Kwonsoo Chun; Salma Jivan; Stefan K. Zeisler |
| A system and method for producing 18F-Fluoride by using a proton beam to irradiate 18Oxygen in gaseous form. The irradiated 18Oxygen is contained in a chamber that includes at least one component to which the produced 18F-Fluoride adheres. A solvent dissolves the produced 18F-Fluoride off of the at least one component while it is in the chamber. The solvent is then processed to obtain the 18F-Fluoride. | ||||||
| 18 | Process for preparing fluorine-18 | US501557 | 1974-08-29 | US3981769A | 1976-09-21 | Harry S. Winchell; Dale K. Wells; James F. Lamb; Samuel B. Beaudry |
| An improved process for preparation of fluorine-18 by a neon (deuteron, alpha particle) fluorine-18 nuclear reaction in a non-reactive enclosed reaction zone wherein a ultrapure product is recovered by heating the reaction zone to a high temperature and removing the product with an inert gas. | ||||||
| 19 | 電気化学的相間移動デバイス及び方法 | JP2012519803 | 2010-07-12 | JP5856954B2 | 2016-02-10 | ボーラー,マルコ; サンパー,ビクター; レンシュ,クリスティアン; ボールド,クリストフ |
| 20 | Method of separating from the electrochemical cell and the solution 18f of carrier-free in one of the electrodes | JP2012512196 | 2010-04-17 | JP2012528929A | 2012-11-15 | ハーマッハー・クルト |
| 本発明は、電気化学セル及び溶液から無担体の放射性核種を一方の電極に分離する方法に関する。 本発明では、電気化学セル内の水溶液から、ダイヤモンドコーティングされたアノード（１）に 18 Ｆを析出させる。 それに続いて、電気化学セルを乾燥して、相関移動触媒を含む液体を投入し、有利には、アノードをカソードとして切り換えて、 18 Ｆを液相に移行させる。 | ||||||
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