序号 专利名 申请号 申请日 公开(公告)号 公开(公告)日 发明人
1 微粒检测设备 CN201110461361.2 2011-12-28 CN102608072A 2012-07-25 权俊亨; 尹斗燮; 卢禧烈; 金秀铉; 柳成润; 权元植; 李侠
发明公开了一种微粒检测设备。微粒检测设备包括:发光的光学元件;会聚光学系统,沿从光学元件发射的光的前进方向设置,以会聚光;微粒路径,沿已经经过会聚光学系统的光的前进方向定位,以使微粒路径与光交叉;光束阻挡单元,阻挡已经经过微粒路径的直接光;会聚透镜,设置在光束阻挡单元的后方;检测器,设置在会聚透镜的后方,以检测被微粒散射的光。由光学元件和会聚光学系统形成的光的焦点可位于微粒路径的后方。照射到微粒的光的焦点可以与微粒的引入位置不同。
2 一种带环形测量池的激光粒度分析仪 CN201710233885.3 2017-04-11 CN106908360A 2017-06-30 张福根; 潘林超
发明公开了一种带环形测量池的激光粒度分析仪,包括激光器、透镜、针孔、柱面镜、环形测量池、探测器组件;激光器、透镜、针孔、柱面镜、环形测量池在同一光轴上并依次设于机架之上;探测器组件包括中心探测器、主探测器、若干个大探测器,大角探测器以环形测量池为中心成环形布设,中心探测器设于主探测器之后,所述环形测量池为圆柱体结构的玻璃环柱,其中部设有圆柱形内腔;所述针孔位置、环形测量池中心和主探测器的通孔设置于上述光轴上;本发明的一种带环形测量池的激光粒度分析仪,其结构简洁、性能稳定、尤其在亚微米颗粒测量上具有良好的效果。
3 生物的检查方法及其装置 CN201380043829.3 2013-08-23 CN104619828A 2015-05-13 中田明子; 伏田真矢; 江藤聪; 松田真典; 保坂幸男
发明提供一种用于测定试样溶液中的生物量的微生物的检查装置(1),具备:搅拌混合机构(7),在以透光材质形成的试样容器(5)进行添加有试样与荧光染色试剂的试样溶液的搅拌、混合;激发光源(10),通过搅拌混合机构(7)搅拌试样溶液(5)并具备对试样容器(5)的被照射面照射激发光的光源;光接收机构(14),检测通过来自激发光源(10)的激发光而荧光发光的光线,并转换为电气信息;以及控制机构(23),通过来自光接收机构(14)的电气信息检测发光数,根据该发光数计算出试样容器(5)中的试样所含的微生物量。
4 観察システム及び観察方法 JP2016134170 2016-07-06 JP2018000141A 2018-01-11 松音 英明; 野中 修
【課題】効率よく撮影を行うことができる観察システムを提供する。
【解決手段】観察システム1は、試料を観察するための複数の撮像部721a,721b…と、試料に対する観察位置を変更するために撮像部721a,721b…の各々を移動させる複数の移動機構723a,723b…と、移動機構723a,723b…の各々に撮像部721a,721b…の各々を移動させながら、撮像部721a,721b…の各々に撮影させるように、移動機構723a,723b…及び撮像部721a,721b…の動作を制御する制御部710とを備える。制御部710は、撮像部721a,721b…の移動パターンについて試料の特徴に応じて異なる制限を課す。
【選択図】図19
5 OPTICAL MICRO-PARTICLES DETECTOR US15842889 2017-12-15 US20190072476A1 2019-03-07 Wei-Lan Chiu; Hsiang-Hung Chang
An optical micro-particle detector including a light source, a gas channel and a plurality of optical detectors is provided. The light source is configured to generate a light beam. The gas channel has at least one curved segment. The curved segment has a light entrance and a plurality of light exits. The light beam from the light source enters the gas channel through the light entrance. The plurality of optical detectors are optically coupled to the light exits, respectively.
6 Integrated detection device, in particular detector of particles such as particulates or alpha particles US14748961 2015-06-24 US10132934B2 2018-11-20 Sara Loi; Alberto Pagani
A detection device is formed in a body of semiconductor material having a first face, a second face, and a cavity. A detection area formed in the cavity, and a gas pump is integrated in the body and configured to force movement of gas towards the detection area. A detection system of an optical type or a detector of alpha particles is arranged at least in part in the detection area.
7 FLUID PROCESSING MICRO-FEATURE DEVICES AND METHODS US15151745 2016-05-11 US20170059459A1 2017-03-02 Daniel R. McPeak; Ka Man Lee
The present description provides, in some embodiments, an apparatus for mixing a fluid in a circuit having an inlet channel defining a flow path for a fluid including particulate matter, a first reagent channel in fluid communication with the inlet channel and defining a first reagent flow path for a first reagent, the inlet channel and first reagent channel configured to shear the fluid entering the first reagent channel from the inlet channel at a first junction, a shearing channel in fluid communication with the inlet channel and first reagent channel at the first junction, and a diffusion channel in fluid communication with the shearing channel at a second junction, the sheared fluid collectable into the diffusion channel such that the fluid is compressed at least in part by the first reagent to have a thickness close to a diameter of the particulate matter in the fluid.
8 Cell Construction For Light Scatter Detectors Having Self-Focusing Properties US13129933 2009-11-19 US20110242535A1 2011-10-06 Diethelm Fröse
The invention relates to a device and to a method for measuring the scattered light about molecules present in a suspension, wherein the suspension is fed through a measurement cell. The measurement cell is produced as a segment of a curved surface, particularly an ellipsoid, a hyperbolic shape, a parabolic shape, or a circle, and comprises a curved and a flat surface. Light-sensitive detectors are disposed about the curved surface and capture the scattered light.
9 Method and system for multi-pass laser-induced incandescence US15239634 2016-08-17 US10067049B1 2018-09-04 Ray Bambha; Hope A. Michelsen
Various technologies for measurement of properties of a particulate suspended in a gas phase via laser-induced incandescence (LII) are described herein. A beam of light can be emitted into a multi-pass optical cell using a laser. The multi-pass optical cell comprises a system of one or more mirrors that repeatedly reflects the beam through a measurement region, stimulating incandescence of particulates present in the measurement region. An LII detection system having a field of view that encompasses the measurement region then receives blackbody or quasi-blackbody radiation emitted by the incandescing particles and outputs data indicative of one or more properties of the particulates in the measurement region.
10 Method for examining microorganisms and examination apparatus for microorganisms US14423134 2013-08-23 US09915601B2 2018-03-13 Akiko Nakata; Shinya Fushida; Akira Eto; Masanori Matsuda; Yukio Hosaka
An examination apparatus 1 for microorganisms for measuring an amount of microorganisms in a sample solution, the apparatus including stirring and mixing means 7 for stirring and mixing the sample solution into which a sample and a fluorescent staining reagent are added, in a sample container 5 formed of a material allowing light to pass through, an excitation light source 10 including a light source that irradiates an irradiation target surface of the sample container 5 with excitation light while the sample solution is being stirred by the stirring and mixing means 7, light receiving means 14 for detecting light and converting the light resulting from a fluorescent emission caused by excitation light from the excitation light source 10, into an electric signal, and control means 23 for detecting the number of emissions based on the electric signal from the light receiving means 14 and calculating the amount of the microorganisms contained in the sample in the sample container 5 based on the number of emissions.
11 Smartphone compatible on-chip biodetection using integrated optical component and microfluidic channel with nanopillar array US14965948 2015-12-11 US20170167981A1 2017-06-15 Huan Hu; Oki Gunawan; Ning Li; Devendra K. Sadana; Joshua T. Smith; William T. Spratt; Yann Astier
Methods, apparatuses, and computer program products are provided where fluid, such as a blood sample, is entered into a microfluidic channel in a microchip where the microfluidic channel possesses a micro/nanopillar array for sorting molecules by size. When the fluid passes through the micro/nanopillar array it is separated into particles of interest or particles not of interest or both. When particles of interest are lit by a light source via a first waveguide in the microchip connecting the light source to the microfluidic channel, then lighted particles of interest can be detected by an optical detector via a second waveguide in the microchip connecting the optical detector to the microfluidic channel. The information from the optical detector can be analyzed further by connecting the microchip to a mobile computing device with its own processing abilities or abilities via the internet or cloud.
12 Method for Examining Microorganisms and Examination Apparatus for Microorganisms US14423134 2013-08-23 US20150219548A1 2015-08-06 Akiko Nakata; Shinya Fushida; Akira Eto; Masanori Matsuda; Yukio Hosaka
An examination apparatus 1 for microorganisms for measuring an amount of microorganisms in a sample solution, the apparatus including stirring and mixing means 7 for stirring and mixing the sample solution into which a sample and a fluorescent staining reagent are added, in a sample container 5 formed of a material allowing light to pass through, an excitation light source 10 including a light source that irradiates an irradiation target surface of the sample container 5 with excitation light while the sample solution is being stirred by the stirring and mixing means 7, light receiving means 14 for detecting light and converting the light resulting from a fluorescent emission caused by excitation light from the excitation light source 10, into an electric signal, and control means 23 for detecting the number of emissions based on the electric signal from the light receiving means 14 and calculating the amount of the microorganisms contained in the sample in the sample container 5 based on the number of emissions.
13 METHOD FOR DETERMINING THE AVERAGE RADIUS OF GYRATION OF PARTICLES WITH A SIZE OF LESS THAN OR EQUAL TO 1 MICRON IN A SUSPENSION, AND DEVICE FOR CARRYING OUT THE METHOD US15759280 2016-09-16 US20180180523A1 2018-06-28 Ines FRESE
The invention relates to a method for determining the average radius of gyration (rg) of particles with a size of ≤1 μm in a suspension, and to a device for carrying out the method according to the invention. The method is based on the scattering of linearly polarised electromagnetic radiation on nanoparticles, which, suspended in a solution, are moved through a through-flow cell. The irradiation is carried out perpendicular to the movement direction, wherein the scattering intensity is measured via at least four detectors that are arranged in a defined plane at defined angles. Alternatively, at least one mirror can be used in the position of at least one of the detectors, which deflects the radiation to at least one detector. Based on the scattering intensities, both the average radius of gyration (rg) of the particles as well as the concentration thereof in the suspension can be determined.
14 INTEGRATED DETECTION DEVICE, IN PARTICULAR DETECTOR OF PARTICLES SUCH AS PARTICULATES OR ALPHA PARTICLES US14748961 2015-06-24 US20160077218A1 2016-03-17 Sara LOI; Alberto PAGANI
A detection device is formed in a body of semiconductor material having a first face, a second face, and a cavity. A detection area formed in the cavity, and a gas pump is integrated in the body and configured to force movement of gas towards the detection area. A detection system of an optical type or a detector of alpha particles is arranged at least in part in the detection area.
15 Cell construction for light scatter detectors having self-focusing properties US13129933 2009-11-19 US08576396B2 2013-11-05 Diethelm Fröse
The invention relates to a device and to a method for measuring the scattered light about molecules present in a suspension, wherein the suspension is fed through a measurement cell. The measurement cell is produced as a segment of a curved surface, particularly an ellipsoid, a hyperbolic shape, a parabolic shape, or a circle, and comprises a curved and a flat surface. Light-sensitive detectors are disposed about the curved surface and capture the scattered light.
16 MICROPARTICLE DETECTION APPARATUS US13336486 2011-12-23 US20120162644A1 2012-06-28 Joonhyung KWON; Du Seop Yoon; Hee Yuel Roh; Soo Hyun Kim; Sung Yoon Ryu; Won Sik Kwon; Hyub Lee
A microparticle detection apparatus is provided. The microparticle detection apparatus includes a light emitting optical element, a converging optical system disposed in an advancing direction of light emitted from the optical element to converge the light, a particle path located in an advancing direction of the light having passed through the converging optical system so that the particle path intersects the light, a beam blocking unit to block direct light having passed through the particle path, a condensing lens disposed at the rear of the beam blocking unit, and a detector disposed at the rear of the condensing lens to detect light scattered by particles. A focal point of light formed by the optical element and the converging optical system may be located at the rear of the particle path. A focal point of light irradiated to the particles may be different from the introduction position of the particles.
17 METHOD FOR EXAMINING MICROORGANISM AND DEVICE FOR SAME EP13830429 2013-08-23 EP2889365A4 2016-03-30 NAKATA AKIKO; FUSHIDA SHINYA; ETO AKIRA; MATSUDA MASANORI; HOSAKA YUKIO
An examination apparatus 1 for microorganisms for measuring an amount of microorganisms in a sample solution, the apparatus including stirring and mixing means 7 for stirring and mixing the sample solution into which a sample and a fluorescent staining reagent are added, in a sample container 5 formed of a material allowing light to pass through, an excitation light source 10 including a light source that irradiates an irradiation target surface of the sample container 5 with excitation light while the sample solution is being stirred by the stirring and mixing means 7, light receiving means 14 for detecting light and converting the light resulting from a fluorescent emission caused by excitation light from the excitation light source 10, into an electric signal, and control means 23 for detecting the number of emissions based on the electric signal from the light receiving means 14 and calculating the amount of the microorganisms contained in the sample in the sample container 5 based on the number of emissions.
18 ZELLAUFBAU FÜR LICHTSTREUDETEKTOREN MIT SELBSTFOKUSSIERENDEN EIGENSCHAFTEN EP09808977.4 2009-11-19 EP2361375B1 2018-10-10 FRÖSE, Diethelm
19 Microparticle detection apparatus EP11195834.4 2011-12-27 EP2472248A3 2015-12-16 Kwon, Joonhyung; Yoon, Du Seop; Roh, Hee Yuel; Kim, Soo Hyun; Ryu, Sung Yoon; Kwon, Won Sik; Lee, Hyub

A microparticle detection apparatus is provided. The microparticle detection apparatus includes a light emitting optical element, a converging optical system disposed in an advancing direction of light emitted from the optical element to converge the light, a particle path located in an advancing direction of the light having passed through the converging optical system so that the particle path intersects the light, a beam blocking unit to block direct light having passed through the particle path, a condensing lens disposed at the rear of the beam blocking unit, and a detector disposed at the rear of the condensing lens to detect light scattered by particles. A focal point of light formed by the optical element and the converging optical system may be located at the rear of the particle path. A focal point of light irradiated to the particles may be different from the introduction position of the particles.

20 Microparticle detection apparatus EP11195834.4 2011-12-27 EP2472248A2 2012-07-04 Kwon, Joonhyung; Yoon, Du Seop; Roh, Hee Yuel; Kim, Soo Hyun; Ryu, Sung Yoon; Kwon, Won Sik; Lee, Hyub

A microparticle detection apparatus is provided. The microparticle detection apparatus includes a light emitting optical element, a converging optical system disposed in an advancing direction of light emitted from the optical element to converge the light, a particle path located in an advancing direction of the light having passed through the converging optical system so that the particle path intersects the light, a beam blocking unit to block direct light having passed through the particle path, a condensing lens disposed at the rear of the beam blocking unit, and a detector disposed at the rear of the condensing lens to detect light scattered by particles. A focal point of light formed by the optical element and the converging optical system may be located at the rear of the particle path. A focal point of light irradiated to the particles may be different from the introduction position of the particles.

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