| Document | Document Title |
|---|---|
| US12234450B2 |
Generation of synthetic genomes
Methods for generating synthetic genomes, for example synthetic genomes having desired properties or viable genomes of reduced size, are disclosed. Also disclosed are synthetic genomes produced by the methods disclosed herein and synthetic cells containing the synthetic genomes disclosed herein. |
| US12234448B2 |
Purification of nucleic acids using titanium oxides
The present disclosure relates to systems and methods for purifying nucleic acid. In particular, the present disclosure relates to systems and methods for purifying nucleic acids using metal or metal oxide compositions. |
| US12234447B2 |
Modified compounds and uses thereof
The present disclosure provides oligomeric compound comprising a modified oligonucleotide having a central region comprising one or more modifications. In certain embodiments, the present disclosure provides oligomeric compounds having an improved therapeutic index or an increased maximum tolerated dose. |
| US12234444B2 |
Composition for promoting the growth of lactic acid bacteria comprising growth factors
The present disclosure relates to a composition for promoting the growth of lactic acid bacteria comprising growth factors, and more particularly, to a composition for promoting the growth of lactic acid bacteria comprising growth factors, the composition being capable of efficiently promoting the growth of various lactic acid bacteria strains. |
| US12234443B2 |
Cell recovery apparatus, cell recovery method, cell separation system, and cell separation method
Apparatus, system, and method are disclosed for cell recovery or cell separation. A cell separation system has at least a first container having a first filter for separating a first removal target from a suspension comprising cells and a removal target including at least the first removal target and a second removal target; a cell separation apparatus; a first flow path connecting the first container and the cell separation apparatus; and a first pump interposed in the first flow path for transferring the suspension from the first container to the cell separation apparatus by decompression suction, for example. |
| US12234442B2 |
Intelligent bacterial collection system
An intelligent bacteria collection system includes a bottle opening module and a peristaltic pump module opposite to each other, wherein a guide rail is arranged between the bottle opening module and the peristaltic pump module, and a tray module is placed on the guide rail; a manipulator module and the peristaltic pump module are fixed on an infusion operation platform; a control infusion module is placed on the tray module, which can be moved to and fixed on the infusion operation platform by the manipulator module. The present invention replaces the conventional artificial bacteria collection process, makes the bacteria collection process more rapid, reduces the possible secondary pollution in the manual detection operation process, improves the accuracy of the bacteria collection detection, and improves the work efficiency. The present invention provides high degree of automation, wherein no manual operation is required in the bacteria collection process. |
| US12234435B2 |
Systems and methods for processing juice
This disclosure relates to a method and a system for processing grapes. An example system includes a simulated moving bed (SMB) device configured to receive a feed stream and an eluent stream as inputs and provide an extract stream and a raffinate stream as outputs. The feed stream includes a grape juice, the extract stream includes a high-sugar grape juice, and the raffinate stream includes a low-sugar grape juice. The system also includes fermentation equipment configured to produce a low-alcohol wine from the low-sugar grape juice. |
| US12234430B1 |
Enhancing solubility of water in MCT oil using alcohols
The invention relates to MCT oil/alcohol compositions without visible clouding or phase separation between the MCT and alcohol components at room temperature. The invention encompasses MCT oil/alcohol compositions containing MCT oil, alcohol, and water. The MCT oil/alcohol compositions can be used for mixing oil-soluble, alcohol-soluble, and water-soluble compounds, and for lubricating, disinfecting, sterilizing, cleaning, and coating surfaces. |
| US12234427B2 |
Process for making a laundry detergent composition
The present invention relates to a process for preparing a solid free-flowing particulate laundry detergent composition, wherein the process includes the steps of: (a) forming a mixture by contacting: (i) molten fatty acid; (ii) liquid alkaline ingredient, and (iii) non-ionic surfactant, to obtain a mixture, wherein the mixture includes: (i) partially neutralized fatty acid component; (ii) non-ionic surfactant; and (iii) water, wherein the molar ratio of fatty acid to liquid alkaline ingredient contacted together in step (a) is above 1:1; (b) contacting the mixture obtained in step (a) to a detergent powder to form a solid free-flowing particulate laundry detergent composition, wherein in step (b) the mixture is contacted to the detergent powder by spraying the mixture at a temperature of greater than 50° C. onto the detergent powder, wherein the detergent powder includes a detergent ingredient. |
| US12234426B2 |
Cleaning compositions employing extended chain anionic surfactants
The invention discloses synergistic combinations of surfactant blends and cleaning compositions employing the same. In certain embodiments a surfactant system is disclosed which includes an extended anionic surfactant with novel linker surfactants including one or more of an alkyl glycerol ether, an ethoxylated alkyl glycerol ether, an alcohol ethoxylate and/or a Gemini surfactant. This system forms emulsions with, and can remove greasy and oily stains, even those comprised of non-trans fats. The compositions may be used alone, as a pre-spotter or other pre-treatment or as a part of a soft surface or hard surface cleaning composition. |
| US12234423B2 |
Antifriction coating composition
An antifriction coating formulation composition comprising (a) a soluble resin, (b) an insoluble polymer, (c) optionally a solid lubricant, and (d) a solvent. |
| US12234421B2 |
Carbon dioxide recycle stream processing with ethylene glycol dehydrating in an enhanced oil recovery process
A method for carbon dioxide recycle stream processing with ethylene glycol dehydrating in an enhanced oil recovery process includes receiving a first carbon dioxide recycle stream from a hydrocarbon formation, adding ethylene glycol to the first carbon dioxide recycle stream to produce an ethylene glycol and carbon dioxide recycle stream, condensing the ethylene glycol and carbon dioxide stream to produce a multiphase stream, separating the multiphase stream into a water and ethylene glycol stream and a second carbon dioxide recycle stream, separating the water and ethylene glycol stream into a water stream and an ethylene glycol stream, and separating the second carbon dioxide recycle steam into a carbon dioxide reinjection stream and a natural gas liquids stream. |
| US12234418B2 |
Hydrocarbon stream separation system and method
A system and method for separating a hydrocarbon feed stream by flashing the feed stream under vacuum to form a remaining flashed vapor comprising atmospheric hydrocarbons, vacuum distillable hydrocarbons and a non-volatile liquid; condensing the flashed vapor to a liquid using a two-stage condenser and heat recovery system; and recycling a portion of the condensed liquid to be flashed under vacuum. Separation is accomplished by combining atmospheric and vacuum separation in one column. The non-volatile liquid recovered from the vacuum vessel may comprise asphalt. This process also injects steam generated within the process into the vacuum vessel which is condensed in a two-stage condenser system to augment vacuum and aid in separation. The feed stream may comprise diluted bitumen which may be removed using a feed preparation vessel. |
| US12234417B2 |
Process for separating cyclic paraffins
A feed stream of cyclic paraffins may be separated to obtain an overhead of methylcyclopentane or cyclohexane and a bottoms stream cyclohexane or methylcyclohexane. The overhead stream may be subjected to separation of normal paraffins from non-normal paraffins with the former being isomerized or the entire overhead stream may be isomerized. In a further embodiment, the bottoms stream may be subjected to steam cracking. In an additional embodiment, the feed stream of cyclic paraffins may be formerly subjected to aromatic saturation. |
| US12234413B2 |
Desulfurization process of waste tire pyrolysis oil to produce fuel
A method and system desulfurizes fuel produced from pyrolysis of waste tires and includes hydroprocessing tire pyrolysis oil to desulfurize the tire pyrolysis oil and obtain a hydroprocessed pyrolysis oil. The hydroprocessed oil is distilled into at least two environmentally fuel products selected from the group consisting of kerosene, naphtha, fuel oil, fuel and diesel. By combining hydroprocessing with distillation, and advantageously recycling byproducts, the methods of this disclosure allow for conversion of waste tires into fuel in a manner that is commercially viable and sustainable. |
| US12234412B2 |
Olefin and aromatics production by the catalytic pyrolysis of polymers
The invention comprises methods of catalytically pyrolyzing plastics. Since it has been discovered that plastics provide insufficient coke to provide adequate heat during catalyst regeneration, heat-forming additives can be introduced into the methods. Systems and compositions useful in the catalytic pyrolysis of plastics are also described. |
| US12234407B2 |
Compositions useful for diverting or stopping fluids in subterranean operations
The flow of a fluid may be diverted from a high permeability zone to a low permeability zone of a subterranean formation or well sections may be temporarily isolated by use of particles comprising a mixture of (i) at least one bi-phenyl compound of Compound I, (ii) one mellitic derivative of Compound II, (iii) one chelating agent of Compound III, (iv) one polymer of Compound IV, and (v) an internal breaker for the diverting agents and other additives like gels, foams, acids, brines and various other treatment chemicals. |
| US12234398B2 |
Metal organic framework (MOF) glass composite comprising metal halide perovskite
The present application relates to a metal organic framework (MOF) glass composite comprising metal halide perovskite, and a method for its preparation. |
| US12234394B2 |
Marking element comprising a reinforcement fabric
A marking element (1) for the labelling of a textile, wherein said marking element (1) comprises an adhesive layer (2), a reinforcement fabric (3) and a printable layer (4) which forms an outer surface (5) of the marking element (1), wherein the said outer surface (5) is thermal transfer printable and/or digital printable and wherein the fabric (3) is embedded between the printable layer (4) and the adhesive layer (2), wherein the fabric (3) is a porous fabric (3) having a thickness of at most 1000 μm and in that one or both of the abovementioned layers (2, 4) extend at least partly through the fabric (3) in such a way that the said layers (2, 4) are in direct contact with each other and method for producing such a marking element (1). |
| US12234390B2 |
Debondable compositions
Dual-cure compositions for use in high temperature adhesive applications, and particularly for temporarily adhesively attaching one substrate to another substrate, are provided. These dual-cure adhesives are silicone-based compositions that can be B-staged by exposure UV radiation to provide initial green strength, followed by a C-stage cure to give adhesives that can survive high temperature processes above 200° C., especially above 300° C., yet easy to debond afterwards to allow separation of the top and bottom substrates. |
| US12234388B2 |
Protective film
The present invention relates to a protective film and a polarizing plate comprising the same, and provides a protective film capable of minimizing the amount of static electricity that can be generated upon peeling the protective film. |
| US12234385B2 |
Surfactant, dispersion and adhesive composition
The invention relates to a surfactant comprising a grafted rosin ester which is a rosin ester grafted with a capped polyalkylene glycol, wherein the capped polyalkylene glycol is a polyalkylene glycol capped by an alkyl ether and an aqueous dispersion consisting of an aqueous phase and resin particles dispersed in the aqueous phase, wherein the dispersion comprises the surfactant according to the invention. |
| US12234384B2 |
Adhesion-improving composition for textile material and associated reinforcing textile material
The invention relates to a textile bonding composition comprising a salt of lignosulfonate, an aldehyde hardener thereof, and an elastomer latex. The lignosulfonate salt may be sodium, potassium, magnesium, ammonium, or calcium lignosulfonate. The invention also relates to the use of such a composition for imparting adhesion properties to a reinforcement textile, with regard to a rubber, a reinforcement textile, in particular yarn, cord or textile structure, at least partially coated and/or impregnated with this composition, and a part made of rubber or comprising a rubber, in which the rubber comprises at least one reinforcement textile, on the surface and/or integrated inside the rubber. |
| US12234382B2 |
CMP composition including anionic and cationic inhibitors
A chemical mechanical polishing composition for polishing tungsten or molybdenum comprises, consists essentially of, or consists of a water based liquid carrier, abrasive particles dispersed in the liquid carrier, an amino acid selected from the group consisting of arginine, histidine, cysteine, lysine, and mixtures thereof, an anionic polymer or an anionic surfactant, and an optional amino acid surfactant. A method for chemical mechanical polishing a substrate including a tungsten layer or a molybdenum layer includes contacting the substrate with the above described polishing composition, moving the polishing composition relative to the substrate, and abrading the substrate to remove a portion of the tungsten layer or the molybdenum layer from the substrate and thereby polish the substrate. |
| US12234381B2 |
Mixing system for producing aqueous coating agents with a low VOC
Described herein is a mixer system for producing aqueous coating materials from at least one aqueous pigment paste A, including at least one color pigment, and at least one pigment-free component B, including an aqueous, acrylate-based microgel dispersion having a glass transition temperature Tg of 50 to 60° C., where both the aqueous pigment paste A and the component B each have a VOC value of less than or equal to 250 g/L. Further described herein is a method for producing aqueous coating materials having a VOC content of 0 to 250 g/L, in which the individual components A and B are stored separately and not mixed until shortly before application, to give the aqueous coating material. Further described herein is a method of using the mixer system for producing aqueous coating materials for refinishing and/or for coating automobile bodies and/or plastics parts. |
| US12234367B2 |
Inkjet printing process, ink set of inkjet inks for forming an image on a substrate
An inkjet printing process and an ink set for forming an image on a substrate by applying a plurality of inkjet inks of the ink set on the substrate. The plurality of inkjet inks include at least a first ink and a second ink, each ink comprising: a pigment and a block copolymer dispersant for dispersing the pigment. The block copolymer dispersant includes a first block and a second block where the second block is formed using at least one monomer M2, which monomer M2 is selected from the group consisting of a methacrylate and an acrylate, and where the monomer M2 is an anchoring monomer for anchoring to the pigment. |
| US12234366B2 |
Method for the 3D printing of two-component polyurethane compositions
A method applying a two-component polyurethane composition by means of 3D printing, including steps providing pumpable first component A including at least one polyol having OH functionality in range from 1.5-4 and average molecular weight Mn in range from 250 to 15 000 g/mol, and at least one diol having two hydroxyl groups joined via a C2-C9 carbon chain, and at least one compound T having at least one thiol group; feeding pumpable second component B into continuous mixer's mixing region, where second component B includes at least one polyisocyanate; wherein one of components A and B additionally includes at least one metal catalyst for reaction of hydroxyl groups and isocyanate groups that is able to form thio complexes, and molar ratio of all thiol groups in at least one compound T to all metal atoms in at least one metal catalyst K is between 1:1 and 250:1. |
| US12234363B2 |
Aqueous ink, ink cartridge and ink jet recording method
Provided are an aqueous ink for ink jet capable of recording an image having excellent abrasion resistance and glossiness and an ink cartridge and an ink jet recording method using the aqueous ink. Provided is an aqueous ink for ink jet including a coloring material and a plurality of resins (first resin and second resin) different from the coloring material. The first resin is a resin particle formed of a first polyester resin and the second resin is at least one of (i) a block copolymer containing an A block having no acid group and a B block having an acid group and (ii) a second polyester resin having a sulfonic acid group. Further, an ink cartridge using the aqueous ink and an ink jet recording method in which the aqueous ink is ejected from an ink jet recording head to record an image on a recording medium are provided. |
| US12234362B2 |
Reflective particulate compositions including a particulate mixture having improved hardness, methods of making the same, and methods for analyzing particulate mixture strength
A reflective granular composition including a reflective pigment material including a majority of kaolin clay and a hardening additive including a sodium salt or another salt. A method for making a reflective granular composition includes the steps of mixing together a reflective pigment material including a majority of kaolin clay and a hardening additive including a sodium salt or another salt to form a particulate mixture, forming a slurry from the particulate mixture by adding to the particulate mixture water and a binder material, granulating the slurry, drying the granulated slurry, and kilning the dried, granulated slurry to form the reflective granular composition. Methods of analyzing the strength of a reflective granular composition are also disclosed. |
| US12234359B2 |
Plastic composite resin composition, a method of manufacturing a plastic molded article, and a plastic molded article for radar absorption manufactured using the method
The present disclosure relates to a plastic composite resin composition, a method of manufacturing a plastic molded article using the same, and a plastic molded article for radar absorption manufactured using the method. More particularly, the present disclosure provides a method of improving a radar absorption rate by manufacturing a plastic molded article having pores formed therein using a plastic resin including polyamide, a filler including carbon nanotubes, and a foaming agent. |
| US12234357B2 |
Copolymer blends
Copolymer blends comprising a first copolymer and a second copolymer, wherein the first and second copolymers each independently comprise units of A and B as defined herein. |
| US12234356B2 |
Epoxy compositions containing polyrotaxane additives having improved impact strength
This document relates to epoxy compositions containing a sliding-ring polymer (polyrotaxane) additive and a thermally-curable epoxy resin. The epoxy compositions exhibit increased flexural toughness and impact resistance as compared to the same epoxy composition that does not contain the additive. This document also relates to 3D-printed epoxy compositions containing a sliding-ring polymer (polyrotaxane) additive and a thermally-curable epoxy resin. |
| US12234352B2 |
Rubbery composition and method for producing the same
A rubbery composition is prepared by combining (A) a rubber component, (B) a cellulose, and (C) fluorene compound having a 9,9-bis(aryl)fluorene skeleton. The fluorene compound (C1) may be a compound represented by the following formula (1): wherein a ring Z represents an arene ring, R1 and R2 represent a substituent, X1 represents a heteroatom-containing functional group, k denotes an integer of 0 to 4, n denotes an integer of not less than 1, p denotes an integer of not less than 0. The rubbery composition has improved mechanical properties such as strength, elongation, and hardness. |
| US12234345B2 |
Flame retardant-stabilizer combination for thermoplastic polymers
The invention provides a flame retardant-stabilizer combination for thermoplastic polymers, comprising as component A 20% to 99.7% by weight of phosphinic salt of the formula (I), (I), in which R1 and R2 are each ethyl, M is Al and m is 3; as component B 0.2% to 16% by weight of aluminium salts of ethylbutylphosphinic acid, of dibutylphosphinic acid, of ethylhexylphosphinic acid, of butylhexylphosphinic acid and/or of dihexylphosphinic acid; as component C 0.1% to 80% by weight of a salt of phosphorous acid having the general formula (II) [HP(═O)O2]2−Mm+(II) in which M is Zn and m is 2; as component D 0% to 80% by weight of a salt of phosphorous acid having the general formula (III) [HP(═O)O2]2−3 Mm+2 (III) in which M is Al and m is 3; as component E 0% to 30% by weight of a nitrogen-containing synergist and/or of a phosphorus-containing and/or nitrogen-containing flame retardant; as component F 0% to 10% by weight of an inorganic synergist selected from zinc borate, zinc stannate, boehmite and/or hydrotalcite; as component G 0% to 3% by weight of an organic phosphonite and/or a mixture of an organic phosphonite and an organic phosphite and as component H 0% to 3% by weight of an ester and/or salt of long-chain aliphatic carboxylic acids (fatty acids) typically having chain lengths of C14 to C40, where the sum total of the components is always 100% by weight. |
| US12234343B2 |
Photovoltaic encapsulant films comprising fumed alumina
The present disclosure relates to a curable composition for an encapsulant film, the curable composition comprising: (A) a polyolefin; (B) a fumed alumina; (C) an organic peroxide; (D) a silane coupling agent; (E) a crosslinking co-agent; and, optionally, (F) an additive component comprising a UV stabilizer, wherein the polyolefin has a volume resistivity of less than 4.0E+15 ohm·cm. The present disclosure further relates to an encapsulant film made from such a curable composition and a PV module containing such an encapsulant film. |
| US12234338B2 |
Method for producing foam particles made of thermoplastic elastomers with polyamide segments
A process for producing foam particles composed of thermoplastic elastomers having polyamide segments, comprising the steps: (a) production of a suspension of pellets of the thermoplastic elastomer in a suspension medium, (b) addition of a blowing agent, (c) impregnation of the pellets with the blowing agent by heating of the suspension in a pressure vessel to an impregnation temperature IMT at an impregnation pressure IMP, depressurization of the suspension by emptying of the pressure vessel via a depressurization device and work-up of the foam particles obtained, and also foam particles obtainable by the process. |
| US12234336B2 |
Binder for inorganic fibers and inorganic fiber mat
The present invention provides a binder that is for inorganic fibers and that is characterized by containing (A) 100 parts by mass of a polyvinyl alcohol resin having a degree of polymerization of 100-3500, (B) 1-50 parts by mass of colloidal silica having an average particle size of 100 nm or less, and (C) 3 parts by mass or more of an ammonia-modified copolymer containing maleic anhydride. By using the binder for inorganic fibers according to the present invention, an inorganic fiber mat having resiliency comparable to that of phenolic resins can be fabricated, and the amount of volatile organic compounds released from the inorganic fiber mat is very small. |
| US12234334B2 |
Self-supported elastomeric film having self-healing properties made from a polymer latex
The present invention relates to self-supported elastomeric film made from a composition comprising polymer latex particles bearing ethylenically unsaturated groups pending from the polymeric backbone of the latex particles wherein the ethylenic unsaturation is separated from the polymeric backbone by at least 3 chemical bonds, to an article comprising the self-supported elastomeric film and to a method for making a self-supported elastomeric film from a composition comprising said polymer latex particles. |
| US12234330B2 |
Method for manufacturing stretchable electrochromic device, and stretchable electrochromic device manufactured thereby
The present invention relates to a method for manufacturing a stretchable electrochromic device and a stretchable electrochromic device manufactured thereby, and more specifically, the present invention is characterized in that a stretchable electrochromic device, which is manufactured by stretching color changeable polymer gel, and then coating one surface and/or the other surface thereof with a metal solution, has excellent water resistance and initial transmittance. |
| US12234329B2 |
Methods for forming lignin prepolymers and lignin resins
Methods of forming lignin prepolymers are provided. In an embodiment, such a method comprises adding an acid to an ozonized reaction mixture, the ozonized reaction mixture comprising ozonized lignin having a backbone, and aromatic monomers cleaved from a lignin, under conditions to react the cleaved aromatic monomers with the backbone of the ozonized lignin to form a lignin prepolymer. The methods may further comprise using the lignin prepolymer to form a lignin resin. |
| US12234327B2 |
Anhydride and aromatic functionalized polyorganosiloxanes
A polyorganosiloxanes has an anhydride functionality and an aromatic functionality, wherein a carbon of the aromatic functionality is separated from a carbon of a carbonyl group of the anhydride functionality by a carbon chain, wherein the polyorganosiloxane contains 5 weight-percent or more silicon atoms based on weight of the polyorganosiloxane. |
| US12234325B2 |
Resin composition, prepreg, laminate, metal foil-clad laminate, and printed circuit board
A resin composition, comprising: a modified maleimide resin (A), an active ester resin (B), and an epoxy resin (C); the modified maleimide resin (A) is obtained by means of reacting a maleimide compound (M) having at least two maleimide groups/molecules with an amine compound (N1) having at least one primary amine group/molecule and an amine compound (N2) having at least two primary amine groups/molecules, and the molecular weight distribution is: molecules having a molecular weight between 1000 and 4500 account for 25-60% the total number of molecules. |
| US12234322B2 |
Polyoxyalkylene polymer and curable composition
A polyoxyalkylene polymer including a main chain structure of a polyoxyalkylene and terminal structures bonded to ends of the main chain structure is provided. The terminal structures include a hydrolyzable silyl group and further include a terminal olefin group and/or an internal olefin group. The total number of the hydrolyzable silyl, terminal olefin, and internal olefin groups is more than 1.0 on average per terminal structure, and the ratio of the number of moles of the hydrolyzable silyl groups to the total number of moles of the hydrolyzable silyl, terminal olefin, and internal olefin groups is from 0.3 to 0.7. |
| US12234315B2 |
Molded product and uses thereof
A molded product of the present invention includes a polythiourethane, in which an SH group concentration according to an IR analysis method is 0.30 wt % to 3.0 wt %. |
| US12234311B2 |
Amphiphilic block copolymer
The invention relates to block copolymer comprising i) A first block wherein at least 65 mol-% of the repeating units of the first block are repeating units of the formula (I)—[CH2—CH2—O]—, ii) A second block wherein at least 90 mol-% of the repeating units of the second block are repeating units of at least one of formulae (II) or (III), wherein the groups R1, R2, and R3 independent of each occurrence are selected from hydrocarbyl groups having 1 to 40 carbon atoms, which are optionally substituted by ether or hydroxyl groups, and wherein the groups R1 and R2 are optionally linked to each other such that a nitrogen heterocyclic structure is present, iii) A third block which is different from the first block and the second block and which is more hydrophobic than the first block. |
| US12234309B1 |
High-temperature-resistant deep penetration molecular membrane acid copolymers and preparation methods thereof
The present disclosure provides a high-temperature-resistant deep penetration molecular membrane acid copolymer and a preparation method thereof. The copolymer is formed by polymerizing four raw monomers including 2-acrylamido-2-methylpropanesulphonic acid, vinyl phosphonic acid, alkyl dimethylallyl ammonium chloride, and perfluoropolyether acrylate. The method comprises: S1: mixing and stirring solvent oil, an emulsifier, the alkyl dimethyl allyl ammonium chloride, and the perfluoropolyether acrylate to be dispersed homogeneously to obtain an oil phase; S2: mixing and stirring the 2-acrylamido-2-methylpropanesulphonic acid, the vinyl phosphonic acid, a complexing agent, and distilled water, and adjusting pH to obtain an aqueous phase; S3: slowly dropwise adding the aqueous phase to the oil phase; and S4: introducing nitrogen into the water-in-oil emulsion to remove oxygen, then adding an initiator and carrying out a heating polymerization reaction to obtain copolymer emulsion (i.e., a molecular membrane agent). The copolymer emulsion is added to an acid solution to obtain molecular membrane acid. |
| US12234308B2 |
Polyethylene with a high vinyl content and beneficial rheological properties
The invention relates to a polyethylene which contains a total amount of vinyl groups which is B vinyl groups per 1000 carbon atoms, and B1≤B, wherein B1 is 0.30; and has a complex viscosity (η*) at 0.05 rad/sec, which is X Pas, and X1≤X≤X2, wherein X1 is 10000 and X2 is 30000; and has a complex viscosity (η*) at 300 rad/sec, which is Y Pas, and Y1≤Y≤Y2, wherein Y1 is 5 and Y2 is 350, both complex viscosities (η*) are determined according to method ISO 6721-1 on stabilised samples of the polyethylene, a polymer composition, an article being e.g. a cable, e.g. a power cable, and processes for producing a polyethylene, a polymer composition and an article, and an article; useful in different end applications, such as wire and cable (W&C) applications. |
| US12234302B2 |
Chitosan derivatives and methods for preparing the same
Disclosed is a method of preparing N-alkylated chitosan derivatives by treating chitosan with an acid and subsequently reacting the chitosan with an alkylating agent in the presence of a base. Also provided are novel N-alkylated chitosan derivatives. |
| US12234300B2 |
Conjugated hepcidin mimetics
The present invention provides hepcidin analogues with improved in vivo half lives, and related pharmaceutical compositions and methods of use thereof. |
| US12234299B2 |
Peptides for inducing bacteriocin synthesis and methods to identify and/or select and/or optimize the same
Described herein is a peptide or peptidomimetic with a length of at least 6 residues comprising, consisting essentially of, or consisting of the sequence motif Xaa1-Trp-Xaa2-Xaa3-Xaa4-Xaa5 (SEQ ID NO:1), wherein: Xaa1 represents an aromatic residue (Phe, Tyr, Trp, His), Cys or Ser; Xaa2, Xaa3 and Xaa4 represent any residue; and Xaa5 represents Gly, lie or Val. |
| US12234295B2 |
Chimeric transmembrane protein comprising antibody dimerization domains and a type I cytokine receptor endodomain, encoding nucleic acids thereof and methods of use thereof
The present invention provides a chimeric cytokine receptor (CCR) comprising: (i) an exodomain which binds to a ligand selected from a tumour secreted factor, a chemokine and a cell-surface antigen; and (ii) a cytokine receptor endodomain. |
| US12234293B2 |
Treatment for primary amyloidosis with anti-BCMA binding protein
Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and a proteasome inhibitor (e.g. bortezomib). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone). |
| US12234292B2 |
FN14 antibodies and uses thereof
An antibody or antigen binding fragment thereof that binds to a Fn14, wherein the antibody or antigen binding fragment thereof is an antagonist and non-agonist of Fn14. |
| US12234288B2 |
Immunogenic arginase 2 polypeptides
The present invention relates to novel polypeptides, which are derived from Arginase2. The invention also concerns uses of the polypeptides and compositions comprising the polypeptides. |
| US12234284B2 |
Treatment of kidney injury
Methods of treating and preventing kidney injury through inhibiting interleukin 11 (IL-11)-mediated signalling are disclosed, as well as agents for use in such methods. |
| US12234283B2 |
System for chromatography column qualification in manufacturing methods for producing anti-IL12/IL23 antibody compositions
The present disclosure is directed to a method of operating a chromatography column in methods of manufacture for producing anti-IL-12/IL-23p40 antibodies, e.g., the anti-IL-12/IL-23p40 antibody STELARA® (ustekinumab), specific pharmaceutical compositions of the antibodies, and antigen binding fragments thereof. This method involves collecting column outlet signal and accumulated flow parameters at two or more intervals of at least one mobile phase transition front during operation of the chromatography column comprising column packing. A model gamma cumulative distribution curve is determined based on the collected column outlet signal and accumulated flow parameters for the at least one mobile phase transition front. The height equivalent theoretical plate (HETP) value is calculated for the at least one mobile phase transition front using parameters of the model gamma cumulative distribution curve and the quality of the chromatography column packing is assessed based on the calculated HETP value. If during routine column monitoring, an adverse trend in HETP is observed or the control limits are exceeded, the eluate product quality, column process performance, and/or impurity removal data should be evaluated to ensure product quality for the identified batch. Should any of the product quality or column performance fail the criteria set, appropriate corrective action, such as conditioning, repacking or replacing the column, and qualification should be performed prior to release for further use. |
| US12234278B2 |
Combination of broadly neutralizing HIV antibodies and viral inducers
The present invention relates to methods and agents for preventing the establishment of HIV-1 latent reservoirs or for reducing the size of the reservoirs. Specifically, the disclosure provides methods and agents for preventing the establishment of HIV-1 latent reservoirs or for reducing the size of the reservoirs, the methods comprising administering to the subject a therapeutically effective amount of an isolated anti-HIV antibody, and administering to the subject two or more viral transcription inducers in effective amounts to induce transcription of an HIV provirus in the cells. Further provided are antibodies and viral transcription inducers used in the methods. |
| US12234277B2 |
Hydrophobic interaction chromatography for viral clearance
The present application provides a method for characterizing and/or determining viral clearance capacity of hydrophobic interaction chromatography (HIC) including experimental design for multivariate analysis of viral clearance of HIC. The method provides understanding of the mechanism of the viral clearance using HIC by running a D-Optimal design of experiment including evaluations of multiple factors, such as pH, buffer concentration, column loading concentration, flow rate of column, or hydrophobic strength of the HIC column. |
| US12234271B2 |
Il-2 conjugates and methods of use to treat autoimmune diseases
Disclosed herein are compositions, kits, and methods comprising interleukin (IL) conjugates (e.g., IL-2 conjugates) useful for the treatment of one or more indications. Also described herein are pharmaceutical compositions and kits comprising one or more of the interleukin conjugates (e.g., IL-2 conjugates). |
| US12234253B2 |
Silicone compounds with a substituted amine group and a benefit agent moiety
Silicone compounds, delivery compositions, compositions, packaged products and displays comprising such silicone compounds, and processes for making and using such benefit agent delivery compositions, compositions, packaged products and displays. Such compositions have improved deposition and retention properties that may impart improved benefit characteristics to a composition and/or situs. |
| US12234246B2 |
Solid state forms of baloxavir marboxil
The present disclosure relates to solid state forms of baloxavir marboxil, processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof. |
| US12234245B2 |
Sulfonimidamide compounds as inhibitors of interleukin-1 activity
The present disclosure relates to novel sulfonimidamide compounds and related compounds and their use in treating a disorder responsive to modulation of cytokines such as IL-1β and IL-18, modulation of NLRP3 or inhibition of the activation of NLRP3 or related components of the inflammatory process. |
| US12234242B2 |
Radiopharmaceuticals, radioimaging agents, and uses thereof
The present invention relates to compounds that are useful as radiopharmaceuticals and radioimaging agents which bear a radionuclide-chelating agent. These coordinated compounds are useful in radiotherapy and diagnostic imaging. The invention also relates to methods of diagnosis, prognosis and therapy utilising the non-coordinated and radiolabelled compounds of the invention. |
| US12234239B2 |
Crystalline forms of 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile
The present disclosure provides crystalline forms of 2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(cyclopropylsulfonyl)azetidin-3-yl)acetonitrile, pharmaceutical compositions comprising the crystalline forms, methods of using the crystalline forms, and processes for making the crystalline forms. |
| US12234237B2 |
Folate salts
The invention relates to crystalline folate salts. The salt consists of a folate anion and an organic cation. The folate anion is 5-methyl-(6S)-tetrahydrofolic acid, and the cation is an organic compound which is an alkanolamine selected from the group consisting of choline, N-methylaminoethanol, 2-amino-2-methylpropanol and 2-dimethylaminoethanol. |
| US12234234B2 |
Method for synthesizing 1,7-naphthyridine derivatives
The invention discloses a method for synthesizing 1,7-naphthyridine derivatives, which relates to the technical field of synthesizing pharmaceutical intermediates and organic chemical intermediates, wherein the method includes: (1) 2-chloro-3-amino-pyridine being used as Compound I as a starting material, and protecting an amino group to prepare Compound II; (2) the Compound II reacting with an aldehydation reagent under alkaline conditions to obtain Compound III; (3) cyclizing the Compound III with acrylate compounds under the action of Lewis acid to prepare compound IV. |
| US12234233B2 |
Crystal form of phosphodiesterase inhibitor, preparation method therefor and use thereof
The present invention falls within the technical field of medicine, and in particular relates to a crystal form of a phosphodiesterase inhibitor as shown in formula (I), a preparation method therefor and the use thereof. |
| US12234231B2 |
EIF4E inhibitors and uses thereof
The present invention provides compounds inhibiting eIF4E activity, and compositions and methods of using thereof. |
| US12234228B2 |
Nitric oxide donor and anti-oxidant compounds
In some aspects, the present disclosure provides compounds of the formulae: (A), (B), (III), and/or (IV), wherein the variables are as defined herein. Pharmaceutical compositions of the compounds are also provided. In some aspects, the compounds or compositions of the present disclosure may be used for the treatment of diseases or disorders, such as eye diseases and peripheral arterial diseases such as hind limb ischemia. |
| US12234225B2 |
IL-17 ligands and uses thereof
Provided herein are novel ligands and pharmaceutical compositions thereof which modulate IL-17A. Also provided are methods for preparing the IL-17A modulators. Such compounds may be useful in the treatment and/or prevention of, for example, inflammation, cancer or autoimmune disease. |
| US12234224B2 |
Pyrimidine and pyridine amine compounds and usage thereof in disease treatment
Pyrimidine and Pyridine containing compounds are described herein that are enzyme p70S6K inhibitors useful in the treatment of S6K-dependent or S6K-mediated diseases and conditions, including but not limited to cancer, fibrotic metabolic and certain neurological disorders. |
| US12234221B2 |
Pyridine carboxamide compounds for inhibiting NAV1.8
Pyridine carboxamide compounds for inhibiting NaV1.8 and methods for treating a condition, disease, or disorder associated with an increased NaV1.8 activity or expression are disclosed. |
| US12234220B2 |
Immunomodulatory compounds
Disclosed are immunomodulatory compounds, pharmaceutical compositions containing them, and methods of making and using the compounds to treat diseases and disorders characterized by aberrant protein activity that can be targeted by cereblon. |
| US12234218B2 |
Heterocyclic compounds as modulators of mGluR7
The present invention relates to novel heterocyclic compounds. The invention is also directed to compounds which are modulators of the metabotropic glutamate receptors (mGluR), preferably of the metabotropic glutamate receptor subtype 7 (“mGluR7”). The present invention also relates to pharmaceutical composition comprising such compounds and their use for the treatment or prevention of disorders associated with glutamate dysfunction or in which metabotropic glutamate receptor, preferably mGluR7 subtype of metabotropic glutamate receptors, is involved. |
| US12234216B2 |
Isotopologues salts, crystalline forms, stereoisomers, of methylone and ethylone and methods of use thereof
Described herein are isotopically enriched analogs of methylone (e.g., deuterated analogs of methylone (e.g., (S)-methylone and (R)-methylone) with improved characteristics. Also described herein are salts (such as hydrochloride salt) and solid forms (e.g., crystalline forms) of methylone. Also described herein are stereoisomers (e.g., enantiomers) of methylone. The present disclosure also provides methods of making and methods of use of the methylone or methylone analogs and solid forms of 3,4-methylenedioxy-N-ethylcathinone hydrochloride described herein to treat brain and neurological disorders such as depression. |
| US12234214B2 |
Method for continuously synthesizing 5-hydroxymethylfurfural by using micro-channel reactor
The present discloses relates to a method for continuously synthesizing 5-hydroxymethylfurfural by using a micro-channel reactor, which belongs to the technical field of micro-chemical engineering. The method includes: separately conveying an aqueous glucose solution, which contains FeCl3 and HCl, and methyl butyl ketone to a T-shaped micro-mixer, the T-shaped micro-mixer being in communication with a capillary tube; then enabling an aqueous glucose solution phase and a methyl butyl ketone phase to flow in the capillary tube in a segmented flow manner while performing an HMF synthesis reaction; and collecting a reaction product flowing out of the capillary tube, wherein HMF generated by the reaction is present in an organic phase of the reaction product. The method is easy to operate, has a controllable process, high product yield, a low by-product amount and a short synthesis period, and is a green method for efficient and continuous synthesis of HMF. |
| US12234206B2 |
Bi- and tricyclic compounds for use as aroma chemicals
The present invention relates to bi- and tricyclic compounds of the general formula (I) (I) wherein the dashed lines independently of each other represent a single or a double bond, X represents a group of the formulae X1 to X3 wherein the asterisk denotes the point of attachment to the rest of the molecule, R1a and R1b, independently of each other, are selected from hydrogen or methyl, or R1a together with R1b form a methylene or ethylene group, R2, R3a, R3b, R4, R5a and R5b, independently of each other, are selected from hydrogen or methyl, R6 is selected from hydrogen, methyl or ethyl, and R7 is methyl or ethyl, to a method of preparing said compounds, to the use of a bi- or tricyclic compounds or of mixtures of two or more bi- and tricyclic compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof as aroma chemicals; to the use of a bi- or tricyclic compound for modifying the scent character of a fragranced composition; to an aroma chemical composition containing a bi- or tricyclic compound or a mixture of two or more bi- and tricyclic compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof; and to a method of preparing a fragranced composition or for modifying the scent character of a fragranced composition, comprising incorporating a bi- or tricyclic compound or a mixture of two or more bi- and tricyclic compounds or of a stereoisomer thereof or of a mixture of two or more stereoisomers thereof into said composition. |
| US12234205B1 |
Sulfonylhydrazide derivatives as anticancer agents
Novel sulfonylhydrazide derivatives, a method of synthesizing said compounds, a pharmaceutical composition comprising said compounds and a suitable carrier, and a method of using the compounds. The sulfonylhydrazide derivative compounds, identified as FAAH inhibitors, are useful as anticancer and/or antitumor agents. |
| US12234202B2 |
Covalent inhibitors of coronavirus papain-like protease
A compound having the following structure: wherein: R1 is a linker having the formula —(CH2)n-L1-, wherein L1 contains 1-6 carbon atoms and at least one —NH— linkage and at least one oxygen-containing or sulfur-containing linkage, and n is an integer of 0-3; R2 is a group having the formula —C(Y)-E, wherein Y is O or S, and E is a hydrocarbon group and either: (i) at least one carbon-carbon or carbon-nitrogen unsaturated bond or (ii) at least one alkyl halide group; R3 is selected from H, NR′2, NHC(O)R′, and —(CH2)p-T, wherein T contains at least one —NH— linkage; Ra, Rb, Rc, Rd, Re, and Rf are independently selected from of H, hydrocarbon groups containing 1-3 carbon atoms, fluorine atom, and chlorine atom; X is N or CR9, wherein R9 is selected from H, hydrocarbon groups containing 1-3 carbon atoms, fluorine atom, and chlorine atom; and pharmaceutically acceptable salts thereof. |
| US12234199B2 |
Systems, methods, and devices for methane conversion via gas recycling
In a first stage of a methane conversion system, at least some methane (CH4) in an input gas flow stream can be converted into C2 hydrocarbons, hydrogen gas (H2), and aromatics to provide a first processed stream. The conversion can be direct non-oxidative methane conversion (DNMC). At least some of the aromatics can be removed from the first processed stream to provide a second processed stream. In a second stage of the methane conversion system, at least some of the H2 can be removed from the second processed stream to provide a recycle stream. The recycle stream can be returned to the first stage of the methane conversion system for further conversion of methane and removal of aromatics and H2 products. |
| US12234195B2 |
Biochar coated seeds
The present invention provides for biochar coated particles and a method for coating the particles with biochar. |
| US12234191B2 |
Bioceramic compositions
This invention relates to compositions and applications for a bioceramic composition that includes from about 45 to about 55% by weight of kaolinite (Al2Si2O5(OH)4); from about 5 to about 15% by weight of tourmaline; from about 3 to about 13% by weight of aluminum oxide (Al2O3); from about 11 to about 19% by weight of silicon dioxide (SiO2); and from about 3 wt % to about 13 wt % zirconium oxide (ZrO2). |
| US12234190B2 |
Electrically-conductive asphalt concrete containing carbon fibers
The present application relates to an electrically conductive asphalt mastic (ECAM) composition that includes an asphalt binder, a mineral filler, and a plurality of conductive carbon microfibers, between 3 and 12 mm in length, which are the sole source of electrical conductivity in the ECAM composition where the conductive carbon microfibers and the mineral filler are dispersed in the asphalt binder, and wherein said conductive carbon microfibers are present in the ECAM composition in an amount of less than 2.00% of total volume of the ECAM composition. The application further relates to an electrically conductive asphalt concrete (ECAC) composition that includes an asphalt binder, a mineral filler, an aggregate, and a plurality of conductive carbon microfibers, where the conductive carbon microfibers are the sole source of electrical conductivity in the electrically conductive asphalt concrete composition. |
| US12234188B2 |
Permeable pavement system including a permeable pavement composition and a related method
A permeable pavement system including a permeable pavement composition and a related method are provided. The permeable pavement system includes a first layer of a permeable pavement composition including a quantity of a first permeable pavement material and a quantity of cured carbon fiber composite material (CCFCM) incorporated therewith, the first layer defining a first surface; and a second layer of a second permeable pavement material deposited over a substantial entirety of and covering the first surface of the first layer of the permeable pavement composition, wherein the first layer interfaces with the second layer to at least strengthen the permeable pavement system. |
| US12234185B2 |
Cementitious reagents, methods of manufacturing and uses thereof
Described are cementitious reagent materials produced from globally abundant inorganic feedstocks. Also described are methods for the manufacture of such cementitious reagent materials and forming the reagent materials as microspheroidal glassy particles. Also described are apparatuses, systems and methods for the thermochemical production of glassy cementitious reagents with spheroidal morphology. The apparatuses, systems and methods make use of an in-flight melting/quenching technology such that solid particles are flown in suspension, melted in suspension, and then quenched in suspension. The cementitious reagents can be used in concrete to substantially reduce the CO2 emission associated with cement production. |
| US12234179B2 |
High-definition flicker-free etched glass, manufacturing process therefor, and application thereof
A high-definition flicker-free etched glass, having a glossiness of 110-145, a haze of 3-10, and a definition of 90%-99.5%. The front surface of the glass is an irregular concave-convex lens surface having an average roughness of 0.025 μm-0.050 μm and provided with dents and bumps; the average chord length of the dents is 1.8 μm-10.0 μm; the average depth from the bottom of the dent to the top of the bump is 0.2 μm-0.7 μm; the average chord length of the bumps is 0.1 μm-0.5 μm; when a 250 μm*250 μm area on the front surface of the glass is observed after being amplified 500 times, there are 800-2500 irregular bumps, and the irregular bumps form an array of micro-convex lenses. By means of a sandblasting etching process, the spherical radius of each bump on the front surface of the etched glass is reduced and the focal length of each micro-convex lens is shortened, so that the focal point of light is closer to the surface of the glass, brightness of a high-pixel display device is brighter and more uniform, and it is not prone to see flicker of the focus point by the naked eye any more. |
| US12234173B2 |
Electronic device including back surface plate and manufacturing method of back surface plate
According to various embodiments, a back surface plate configured to form a back surface of an electronic device may include: a first glass part including a first pattern area including a pattern having a predetermined shape on a first surface; and a second glass part, at least a portion of which is disposed on the first surface of the first glass part, the second glass part including a first shape complimentary to the first pattern area, wherein the second glass part may have a color different from the color of the first glass part. |
| US12234169B2 |
Centrifugal dehydrator and centrifugal dehydration method
A centrifugal dehydrator according to an embodiment of the present disclosure for solving the above problems includes: a slurry flow tube through which slurry, in which polymers and water are mixed, flows; a gas flow tube through which a gas flows; a mixture flow tube which is connected from the slurry flow tube and the gas flow tube and through which a mixture of the slurry and the gas flows; a basket into which the mixture is injected from the mixture flow tube and which rotates to apply centrifugal force to the slurry in the mixture; a driving part that allows the basket to rotate; and a porous plate disposed on a peripheral portion of the basket to discharge the water from the slurry to the outside of the basket. |
| US12234166B2 |
Dispensing cartridge alert
A cartridge dispenser having a rotatable sleeve for alerting a person as to when a cartridge dispenser should be replaced based on when the cartridge dispenser is placed in a body of water with the cartridge replacement date carried forward on the cartridge dispenser. |
| US12234165B2 |
Process for producing cationic lignin copolymer under aqueous acid conditions
A water-based process was developed for the synthesis of aminated lignin copolymers with high MW, thermal stability and solubility in water over a wide range of p H values. The cationic lignin copolymer described herein comprises: a grafting ratio of (weight of cationic amine compound)/(weight of lignin) of 70 to 200% and a charge density of +1.4-3.0 meq/g. This cationic lignin copolymer can be used as a flocculant in numerous wastewater streams including municipal and industrial systems and sludge dewatering in the pulp & paper, mining and oil industries. |
| US12234164B2 |
Electrodialysis deionization battery cells
A deionization battery cell including a first electrode compartment containing a first intercalation host electrode and includes a first water stream compartment in fluid communication with the first electrode compartment. The deionization battery cell further includes a second electrode compartment containing a second intercalation host electrode and a second water stream compartment in fluid communication with the second electrode compartment. The deionization battery cell also includes an ion exchange membrane assembly including a plurality of anion exchange membranes separated from each other, and from one or more cation exchange membranes positioned between the anion exchange membranes, by a plurality of intervening water stream compartments. The first and second water stream compartments are separated from one another by the ion exchange membrane assembly. |
| US12234159B2 |
Method and apparatus for recycling waste water from a grouting process
A method of recycling waste water from an offshore grouting process is provided. The method includes the steps of receiving waste water from a grouting equipment cleaning process, passing the waste water into a settling tank where sediment is separated from the waste water, removing water from the settling tank, and re-using the water removed from the settling tank. |
| US12234156B1 |
Method for making nanosilica from glass waste
A method of making nanosilica from glass, the method comprising: gathering glass waste; grinding the glass waste to obtain a glass powder containing nanoparticles; adding the glass powder containing the nanoparticles to a water solution comprising a dispersing agent to obtain a colloidal system containing nanoparticles; separating the nanoparticles from the colloidal system to obtain separated nanoparticles; and drying the separated nanoparticles to obtain nanosilica. |
| US12234152B2 |
Mechanochemical process to produce exfoliated nanoparticles
The invention relates to a mechanochemical process to produce exfoliated nanoparticles comprising the steps of providing a solid feedstock comprising a carbonaceous and/or mineral-based material; providing a flow of an oxidizing gas; introducing the solid feedstock and the flow of an oxidizing gas into a mechanical agitation unit, subjecting the material of the solid feedstock in the presence of the oxidizing gas to a mechanical agitation operation in the mechanical agitation unit at a pressure of at least 1 atm (15 psi). The invention further relates to nanoparticles obtainable by the mechanochemical process and to the use of such nanoparticles. |
| US12234151B2 |
Method for producing graphene and new form of graphene
The invention provides a method for preparing graphene which method comprises the steps of: (a) forming a graphite/water mixture; and (b) introducing the graphite/water mixture into a cavitation reactor using at least two offset nozzles; a cavitation reactor for use in the method wherein the cavitation reactor has a cavitation chamber wherein the cavitation chamber has at least two offset inlet nozzles which are directed towards the centre of the cavitation chamber and at least one outlet; and graphene having a carbon content of at least about 98 wt %. |
| US12234149B2 |
Co-production of hydrogen-enriched compressed natural gas and carbon nanotubes
The present subject matter relates to co-producing H-CNG and CNTs. The process comprises adding catalyst to a first reactor (110) and activating the catalyst and performing a reaction to obtain H-CNG and CNTs. At a first predetermined time after reaction has progressed in the first reactor (110), catalyst is added to a second reactor (120), activated, and then the reaction proceeds simultaneously in the first reactor (110) and second reactor (120). The use of multiple reactors with staggered start times helps in the continuous co-production of H-CNG and CNTs. Catalyst preparation process is integrated with the co-production process for efficient heat recovery. The first and second reactors are fluidized bed reactors with cantilever trays having weirs for controlling the residence time of the catalyst in the reactor and thereby controlling the purity of CNTs produced. |
| US12234147B2 |
Lithium-containing chalcophosphates for thermal neutron detection
Inorganic compounds having the formula LiMP2Q6, where M is Ga, In, Bi, Sb, As, Al, or a combination thereof, and Q is S and/or Se, are provided. Methods and devices for detecting incident neutrons and alpha-particles using the compounds are also provided. For thermal neutron detection applications, the compounds can be enriched with lithium-6 isotope (6Li) to enhance their neutron detecting capabilities. |
| US12234146B2 |
Transportable system for creating an oxidation reduction potential (ORP) in water via multi-path manifold for mixing and distribution
A transportable system for creating an ORP in water includes an ozone supply unit and a manifold housed in separate enclosures on a wheeled frame. The ozone supply unit feeds into the manifold which contains a plurality of fluid paths and has one or more ozone intake ports. The ozone intake ports are fluidically coupled to one or more ozone output ports of the ozone supply unit. The manifold includes flow switches configured to transmit control signals to one or more controllers of the ozone supply unit in response to sensing a flow of water through the fluid paths in order to cause the ozone supply unit to generate ozone. The manifold also includes fluid mixers that are fluidically coupled to the ozone intake ports and configured to introduce the ozone generated by the ozone supply unit into the water flowing through the fluid paths. |
| US12234143B2 |
Microelectromechanical system component or a microfluidic component comprising a free-hanging or free-standing microchannel
The invention relates to a microelectromechanical system (MEMS) component or microfluidic component comprising a free-hanging or free-standing microchannel (1), as well as methods for manufacturing such a microchannel, as well as a flow sensor, e.g. a thermal flow sensor or a Coriolis flow sensor, pressure sensor or multi-parameter sensor, valve, pump or microheater, comprising such a microelectromechanical system component or microfluidic component. The MEMS component allows to increase the flow range and/or decrease the pressure drop of for instance a micro Coriolis mass flow meter by increasing the channel diameter, while maintaining its advantages. |
| US12234141B2 |
Outgassing material coated cavity for a micro-electro mechanical system device and methods for forming the same
A MEMS support structure and a cap structure are provided. At least one vertically-extending trench is formed into the MEMS support structure or a portion of the cap structure. A vertically-extending outgassing material portion having a surface that is physically exposed to a respective vertically-extending cavity is formed in each of the at least one vertically-extending trench. A matrix material layer is attached to the MEMS support structure. A movable element laterally confined within a matrix layer is formed by patterning the matrix material layer. The matrix layer is bonded to the cap structure. A sealed chamber containing the movable element is formed. Each vertically-extending outgassing material portion has a surface that is physically exposed to the sealed chamber, and outgases a gas to increase the pressure in the sealed chamber. |
| US12234139B2 |
Fluid dispensing systems and methods
A dispenser system includes a first container configured to contain a first fluid, a second container configured to contain a second fluid, a faucet coupled with the first container and the second container via first and second hoses, respectively, and including first and second switches installed on the faucet, and a controller configured to control dispensing of the first and second fluids through the faucet. When the first switch is turned on while the second switch is turned off, the controller dispenses the first fluid to the faucet through the first hose. When the first switch is turned off while the second switch is turned on, the controller dispenses the second fluid to the faucet through the second hose. The dispenser system is configured and dimensioned to prevent cross contamination between the first and second hoses. |
| US12234134B2 |
Net loading hanger with functional hooks
A lift system for a baler implement includes a hanger including a hanger body defining a first aperture and a second aperture. The first aperture is positioned such that a center of gravity of the hanger body is located within the first aperture. The second aperture is positioned vertically below the first aperture. A lift line includes an upper end portion secured to a line actuator, and a lower end portion supporting the hanger. The lower end portion of the lift line is routed through the first aperture and the second aperture and is secured relative to the hanger such that the lift line applies a lift force to the hanger body at the center of gravity of the hanger body. The hanger includes a first pocket and a second pocket at respective ends of the hanger body shaped to capture respective lifting bands on a roll of wrap material. |
| US12234130B2 |
Fairlead with integrated positioning device
A positioning system includes a plurality of sensors, a frame, including a plurality of rollers, and a housing. The housing includes at least one guide rod and a driving module. The at least one guide rod is disposed laterally within the housing. The frame is coupled to the at least one guide rod, such that the frame is configured to translate laterally along the at least one guide rod. The driving module is configured to translate the frame along the at least one guide rod, responsive to a signal received from the plurality of sensors. |
| US12234128B2 |
Vacuum extraction for material sorting applications
Systems and methods for vacuum extraction for material sorting applications are provided. In one embodiments, a vacuum object sorting system comprises: a vacuum extraction assembly that includes at least one vacuum extractor device having an inlet and an outlet, wherein the at least one vacuum extractor device is configured to convert a controlled compressed air stream into a channeled vacuum airflow entering the inlet and exiting the outlet; and an object recognition device coupled to sorting control logic and electronics, wherein the controlled compressed air stream is controlled in response to a signal generated by the object recognition device; wherein the at least one vacuum extractor device is configured to capture a target object identified by the sorting control logic and electronics utilizing the channeled vacuum airflow, and further utilizing the channeled vacuum airflow, to pass the target object through the inlet and outlet to a deposit location. |
| US12234123B2 |
Elevator door interlock device, elevator door interlock operation method and elevator system
An elevator door interlock device, an elevator door interlock operation method and an elevator system. The elevator door interlock device is arranged on an elevator car and has a first state in which to operate a landing door lock at a current arrival position of the elevator car to open or close a landing door, and a second state in which it makes no contact with the landing door lock, and the elevator door interlock device is configured to be in the first state when the elevator car travels in a vertical direction, and to be in the second state when the elevator car travels in a horizontal direction and to switch to the first state to open or close the landing door after the elevator car reaches a landing door position, and to return to the second state when the elevator car continues to travel in the horizontal direction. |
| US12234117B2 |
Recording-material-transporting apparatus and image forming system
A recording-material-transporting apparatus includes: a transport unit that transports a recording material along a transport path; at least one image reader that reads an image formed on the recording material transported by the transport unit; and a common housing that supports the transport unit and the at least one image reader. The transport path is accessible by a user through at least one gap existing between the transport path and the at least one image reader. |
| US12234113B2 |
Splice interrupt mechanism
A system is disclosed. The system comprises one or more print controllers to generate print interrupt instructions in response to receiving a web splice signal indicating that a web splice on a web print medium has been detected, wherein the print interrupt instructions indicate a first side sheet image and a second side sheet image within a print job to pause prior to stopping printing, wherein the print interrupt instructions comprise gap instructions to open a first printhead gap at the first print engine and to open a second printhead gap at the second print engine, control printing of the first side sheet image on a first side of a web at a first print engine based on the print interrupt instructions, control printing of the second side sheet image to a second side of the web at a second print engine based on the print interrupt instructions, wherein the print interrupt instructions are generated based on a determination of an interrupted first side sheet image to be paused prior to opening the first printhead gap and a determination of an interrupted second side sheet image to be paused prior to opening the second printhead gap. |
| US12234109B2 |
Supermarket basket lifting-stacking machine
The invention relates to a basket lifting-stacking machine, for lifting baskets by means of a rack-and-pinion lifting system driven by a single-phase self-braking motor so that the customer can lift the basket to the height that best suits their own height, with automatic movement of the basket towards the basket-stacking module, by means of conveyor belts and an electromagnet driven by a linear actuator, and automatic basket stacking with a platform that adapts its height to the number of baskets stacked by means of a scissor lift system driven by a linear actuator with a potentiometer. |
| US12234107B2 |
Apparatus and method for transferring the substrate
A substrate transferring apparatus including a non-contact type driving unit is provided. The substrate transferring apparatus comprises a stator assembly including a driving surface and an electromagnetic generating module, a first mover including a first magnet module facing the electromagnetic generating module and floating and moving on the driving surface, and including a first inclined surface, a second mover including a second magnet module facing the electromagnetic generating module and floating and moving on the driving surface, and including a second inclined surface, and a transfer member disposed between the first mover and the second mover and moving along the first inclined surface and the second inclined surface according to a distance between the first mover and the second mover. |
| US12234106B1 |
Apparatus for transferring substrate in vaccum chamber
A substrate transfer apparatus transfers a substrate in a vacuum chamber. The substrate transfer apparatus includes an elevating robot, a travel robot and a transfer robot. The elevating robot includes an elevating plate through which through-holes are formed, and hollow elevating shafts, wherein each central axis of the hollow elevating shafts corresponds to each center of the through-holes, wherein the elevating robot is sealably coupled with a vacuum chamber through-hole. The travel robot includes a travel arm platform through which coupling holes are formed, wherein each of the hollow elevating shafts is inserted into each lower space of each of the coupling holes, a first travel arm part including a (1_1)-st and a (1_2)-nd travel link arms, second travel arm parts including a (2_1)-st and a (2_2)-nd travel link arms, and a transfer robot coupling part coupled with the (1_2)-nd and the (2_2)-nd travel link arms. |
| US12234102B2 |
Rubber plug supply apparatus
A rubber plug supply apparatus 10 according to the present invention includes a supply device 20, a sensor 32, an orientation correction device 40, and an accommodation assistance device 107. The supply device 20 includes an accommodation portion 21 accommodating a rubber plug 5 and a discharge port 22b, from which the rubber plug 5 is discharged. The sensor 32 detects the orientation of the rubber plug 5 supplied by the supply device 20. The orientation correction device 40 includes an accommodation hole 51 accommodating the rubber plug 5, and changes the orientation of the rubber plug 5 to a predetermined orientation in the case where the orientation of the rubber plug 5 detected by the sensor 32 is different from the predetermined orientation. The accommodation assistance device 107 moves one of, or both of, the accommodation hole 51 and the discharge port 22b to move the position of the accommodation hole 51 with respect to the discharge port 22b at least between a first position P1 directly facing the discharge port 22b and a second position P2 shifted from the first position P1 and facing a part of the discharge port 22b. |
| US12234099B2 |
Crop unloader drive with tensioner
A crop unloader system comprising: an elevator assembly, a boom assembly, a flexible drive, and a tensioning assembly. The elevator assembly has a frame, an elevator drive and drive motor, and an elevator drive output. The boom assembly has a frame connected to the elevator frame at a boom pivot axis to rotate through a range of motion, and an unloader drive input. The flexible drive is operatively connected between the elevator drive output and the unloader drive input. The tensioning assembly has a tensioner link and a control link that are pivotally to each other and with one of the two links each pivotally connected to one of the boom and elevator frame. An idler wheel is on the tensioner link. The tensioning assembly maintains a tension load on the endless flexible drive within a predetermined range, throughout the range of motion of the boom frame. |
| US12234098B2 |
Conveying system for longitudinally transporting elongate items
A conveying system for longitudinally transporting elongate items, including a circulating traction belt and a supporting structure for the circulating traction belt, wherein a plurality of supports are connected by means of at least one traction element to form the circulating traction belt, wherein each of the supports comprises an indentation for supporting the elongate item. Each of the supports is fastened at at least two spaced-apart fastening points to the at least one traction element and the circulating traction belt is mounted, at least in a conveying region of the conveying system, by rollers so as to be movable with respect to the supporting structure. |
| US12234096B2 |
Chute liner
The disclosure relates to a chute liner for mounting on a shelf of a material transfer chute. The shelf has at least one locking formation aperture formed therein. The chute liner has a base for mounting on the shelf. The base has an operatively upper surface that comes into contact with material passing through the chute and an opposed operatively lower surface. The base has at least one mounting formation that depends from the operatively lower surface of the base that defines a passage which in use is passed through the locking formation aperture in the shelf. The chute liner also has a locking member passed through the passage until it operatively engages the mounting formation to lock the base to the shelf. |
| US12234093B2 |
Method and apparatus for sorting or retrieving items
A method and apparatus are provided for sorting or retrieving items to/from a plurality of destinations areas. The items are loaded onto one of a plurality of independently controlled delivery vehicles. The delivery vehicles follow a track that guides the delivery vehicles to/from the destination areas, which are positioned along the track. Once at the appropriate destination area, an item is transferred between the delivery vehicle and the destination area. |
| US12234092B2 |
System-directed single line pick batching
A system-directed single line pick batching is described. In an example implementation, the system may receive data describing a set of orders including SKU identifiers associated with items in the orders, identify an eligible cart, and assign a location to a task queue of the cart based on the location being associated with a particular SKU identifier. In some instances, the location or SKU identifier may be determined based on an order with a certain quantity of different SKU identifiers. In some instances, the system may navigate the cart to the location and instruct the item to be picked from the location. In response to completion of the pick of the item, the system may navigate the cart to an end point. |
| US12234090B1 |
Metal detector for a receptacle
A metal detector is used with a receptacle to receive refuse. The metal detector includes a body defining an opening, a controller, and a coil wound around the opening. The controller detects changes to a magnetic field generated by the coil when an object comprised of a metallic material that is located proximate the coil interacts with the magnetic field and induces a voltage within the coil. A capacitive sensor is mounted to the body and communicates with the controller. The controller is configured to detect the object located within the opening based on a proximity signal produced by the capacitive sensor when the object interacts with an electrical field of the capacitive sensor. When the controller determines that the object is comprised of a metallic material and disposed within the opening based on the induced voltage and the proximity signal, the metal detector correspondingly produces an alarm. |
| US12234089B2 |
Medical waste container transport device and system
A transport device to removably receive a medical waste container for transport of the medical waste container includes a body having a base wall with at least one opening for receiving a medical waste container. A portion of the base wall defining the at least one opening is configured to engage and completely surround an exterior of the medical waste container. The body further includes a side wall extending from the base wall, the base wall and side wall together defining a cavity. A cover is movably coupled to the side wall and is movable between a closed position, in which the cover cooperates with the side wall to close a top of the cavity, and an open position, in which the cavity is open at the top. |
| US12234088B2 |
Dust and allergen control for surface cleaning apparatus
A system comprising a vacuum cleaner and an apparatus for receiving dirt from a dirt collection region of the vacuum cleaner. The apparatus has an air flow passage from an inlet port to a clean air outlet, wherein the dirt collection region of the vacuum cleaner is positionable in air flow communication with the inlet port. The apparatus also has an air treatment member positioned in the air flow passage downstream from the inlet port wherein the air treatment member comprises an apparatus dirt collection region. When the apparatus is standing on the floor, the apparatus has an upper end which has the inlet port, and the dirt collection region of the vacuum cleaner is moved in a downward direction to an emptying position in which the dirt collection region of the vacuum cleaner is in air flow communication with the inlet port. |
| US12234086B2 |
Waste receptacle
A waste receptacle includes a housing defining a rim, the rim defining a rim opening configured to receive a liner. The waste receptacle may include a plurality of retention tabs extending from the rim. At least one retention tab of the plurality of retention tabs extends outward relative to the rim opening. The waste receptacle may include a lid, a lift-rod, a pedal operatively coupled to the lift-rod, and a locking tab configured to lock or unlock the lift-rod. The waste receptacle may include a foldable pedal being foldable about a fold axis between a pedal-extended configuration and a pedal-folded configuration. The waste receptacle may include a plurality of dampening feet. |
| US12234083B2 |
Collapsible container with slidable retractable wall
In multiple embodiments, a collapsible container includes a base and a plurality of walls pivotably connected to edges of the base and collapsible onto the base. The plurality of walls include a retractable first wall. The first wall includes a frame having a lower horizontal portion and a pair of upstanding vertical portions extending upward from the lower horizontal portion to define an access opening therebetween. An upper beam is slidably coupled to the vertical portions and movable between a first position away from the lower horizontal portion of the frame and a second position proximate the lower horizontal portion of the frame. In some embodiments, the first wall includes a mid-beam coupled to the upper beam. The mid-beam is spaced away from the upper beam and spaced away from the lower horizontal portion of the frame when the upper beam is in the first position. |
| US12234082B2 |
Rotationally stabilized wine bottle with rotationally controlling bumpers
A substantially cylindrical glass bottle that is susceptible to accidental rolling and breakage when stored on its side has been structurally modified by forming a series of between approximately 8 and 24 small protrusions or bumpers spaced apart at regular intervals along either one path or two separated paths around the bottle's circumference at certain distances from the shoulder and base of the bottle. The bumpers project outward between approximately 2 mm to 6 mm from the bottle's outer sidewall surface, and pairs of these bumpers stably support the bottle stored on its side without the bottle rocking or rolling. |
| US12234081B2 |
Cell box and cell box device
A cell box includes a bottom plate on which an object to be packed is placed, a sidewall formed at a peripheral edge of the bottom plate, and a spacer that is switched between a first state where one end of the spacer protrudes by a first distance from a sidewall toward a side of an accommodation space accommodating the object to be packed, and a second state where the one end does not protrude from the sidewall toward the side of the accommodation space. |
| US12234073B2 |
Package
A package with a first container defining a storage region defined by side walls extending upward from a lower region to a top surface. A first cartridge is positioned within the storage region of the first container. A card is mounted to the top surface of the first container. A leading edge of the card and a front face of the first container define an opening dimensioned to receive a handle. |
| US12234069B2 |
Reclosing septum cap for medical sample transport and processing
A pierceable cap may be used for containing sample specimens. The pierceable cap may prevent escape of sample specimens before transfer with a transfer device. The pierceable cap may fit over a vessel. An access port in the shell of the pierceable cap may allow passage of a transfer device through the pierceable cap. The shell receives a septum that has four half dome indentations, each indentation defining a quadrant of the septum interior. The indentations are separated by the septum floor which extends along respective first and second diameters of the septum and intersect at approximately ninety degrees. The half dome indentations guide a transfer device to the partially slitted portion of the septum floor. |
| US12234067B2 |
Transport structure for lead-acid battery
A transport structure (1) for a lead-acid battery (10) includes: a packing box (20) in which a lead-acid battery (10) is packed, in which an upper wall portion (23) is formed by two flaps (24) extending from two first side wall portions (21) facing each other of the packing box (20), and in which a distal end portion (26) of at least one of the flaps (24) is bent and inserted into the packing box (20); and an upper buffer body (42A) disposed outside the upper wall portion (23), the upper buffer body (42A) including an upper wall portion (51) facing the upper wall portion (23). |
| US12234065B2 |
Tray for transport and storage of products and method for use thereof
A tray comprises a foldable sheet including: a bottom having a first sector with a folding line that defines a first joining zone, and a second sector joined to the first sector in the first joining zone; end walls each having an interior surface; support surfaces each extending from an end wall, where the support surfaces are oriented to support the weight of another stacked tray; first flaps each extending from a support surface, where each of the first flaps is folded towards an interior of the tray and having a surface facing and separated from the interior surface of an end wall; side walls; and a second flap extending from a side wall. The second flap is placeable a first position on a side wall for reinforcement and in a second position substantially perpendicular to the side walls to serve as a lid. |
| US12234061B2 |
Container closure having a hinge and a grip projection
A container closure including a retaining ring which extends around a reference axis of the container closure, a cap part and a hinge which connects the retaining ring to the cap part. The cap part has an end plate, an enclosing circumferential wall and a grip projection which extends radially outward from the circumferential wall, axially with a distance to the end plate. A deformable region of the circumferential wall extends diametrically opposite the hinge, between the end plate and the grip projection, and has a latching projection directed radially inward, a lower wall section which lies between the latching projection and the grip projection and an upper wall section which lies between the latching projection and the end plate. |
| US12234060B2 |
Child-resistant reclosable bags
A child-resistant reclosable bag includes a container configured to retain one or more items, and a zipper coupled to the container. The zipper includes one or more primary seals, and one or more secondary seals at one or more defined locations. The one or more secondary seals at the one or more defined locations provide one or more areas to be engaged to peel open the container. |
| US12234059B2 |
Method of forming a paper container and related materials
Materials for coating paper sleeve blanks are provided, wherein the paper sleeve blank includes a multilayer coating. The multilayer coating includes a barrier layer and a top coat. At least two polymeric layers, including a top coat, are added to one side of the paper sleeve blank and the bottom blank. A container forming machine wraps and seals the multilayer coated paper sleeve blank to the coated bottom blank. |
| US12234050B2 |
Linear filling machine for filling containers with filling material
A linear filling machine for filling containers that are transported in groups along a linear conveying path has a plurality of machine sections following one another along the conveying path. The respective machine sections form an input station for receiving the containers, a handling station for treating the containers, a filling station for filling the containers, and a discharge station for delivering the containers. The machine sections are exchangeable machine modules, wherein each machine module forms an independent functional unit with a power supply unit and a media supply unit, in particular a pneumatic medium supply unit. The supply units are arranged spatially separate from one another, with the power supply unit arranged on a first side and the pneumatic medium supply unit arranged on an opposite, second side of the machine module. |
| US12234046B2 |
Methods of making and transporting frozen food compositions and re-using components utilized therein
A method of transporting one or more frozen food compositions can include providing a first container; dispensing at least one comestible ingredient into the first container, the dispensing of the at least one comestible ingredient into the first container is performed at a first location; positioning a first lid on the first container containing the at least one comestible ingredient; freezing the first container with the first lid thereon and the at least one comestible ingredient therein to form a first frozen food composition in the first container; attaching a first jacket to at least one of (a) the first container with the first frozen food composition therein or (b) the first lid on the first container with the first frozen food composition therein; and transporting the first frozen food composition to a second location by transporting the first container in the first jacket to the second location. |
| US12234044B2 |
Wildlife warning system for aerial vehicle
An aerial vehicle according to the present invention includes: at least one rotor configured to generate an air flow for lifting; and at least one sound producing structure having an opening and configured to produce sound for scaring birds and animals when the air flow generated by the rotor causes air to flow into the opening. |
| US12234040B2 |
Multi-purpose planet rover
A multi-purpose planet planetary exploration rover is provided in this invention, which relates to the field of planet exploration. The multi-purpose planetary exploration rover includes a case body, mounted with a first wheel at left and right sides respectively; and a cantilever, having a front end connected to the case body, a rear end of the cantilever being mounted with a second wheel; wherein the cantilever is rotated or fixed relative to the case body, the second wheel is steered relative to the cantilever, and the first wheel and the second wheel are used to drive the multi-purpose planetary exploration rover. Compared with the prior art, the multi-purpose planetary exploration rover of this invention can effectively explore special geographic locations such as cliffs, volcanic craters, craters and lava caves on alien planets. |
| US12234039B2 |
Repeating ground track orbits for a reusable launch vehicle
Methods for a reusable space vehicle to land at substantially the same location as its launching site. The vehicle traveling in a particular orbit, which is a repeating ground track orbit, allows for launching and landing at the same location once per day. The repeating ground track orbits that allow for launching and landing at the same location once per day overfly the launch and landing site once per day. Launching and landing at the same site provides a number of direct advantages. For example, the just-landed vehicle may be transported a relatively short distance to the launch site, reconditioned relatively quickly, and be ready for a quick turn-around launch. |
| US12234038B2 |
Recoverable rocket and an associated recovery method
A recoverable rocket and an associated recovery method are disclosed. A recoverable rocket comprises a rocket body and at least two side wings. One end of each side wing is connected to the casing of the rocket body, and the other end is connected to a deceleration mechanism; the deceleration mechanism comprises a turbine engine and a propeller. The propeller is arranged below the turbine engine. The propeller is connected to the drive shaft of the turbine engine, and the turbine engine drives the propeller to rotate in the air to generate a thrust which decelerates the rocket during recovery. The rocket body comprises a structural system, a propulsion system, a control system and a set of landing legs. The advantage of this invention is that it realizes the recovery of rockets. |
| US12234036B2 |
Vacuum film with ventilation
Film for the repair of aircraft components made of fiber-reinforced thermoplastic including an embossed film made of polyimide and a coating made of an electrically conductive material. |
| US12234034B2 |
Aircraft opening plug and installation tool
A cover for an opening on the exterior of an aircraft that contains a fire-resistant, high-temperature tolerant foam encased in a cover made of an aramid fabric. The cover is friction-fitted to the interior of the orifice. The cover can contain one or more durable rings embedded in the fire-resistant, high-temperature tolerant foam meant to protrude outward from the rest of the cover of the body to contact an interior of the orifice into which they are inserted holding the cover in place with friction instead of fasteners. |
| US12234032B2 |
Quick-connect fittings for convertible cargo handling assemblies
A quick-connect fitting for a convertible cargo handling assembly may comprise a fixed portion and a coupling component. The fixed portion may be secured to an aircraft frame structure. The coupling component may be coupled to a removable cargo handling component. The coupling component may be configured to rotate relative to the fixed portion. |
| US12234029B2 |
Device and method to intercept an aerial vehicle
An airframe is provided that can be flown under the control of an operator or an automated sensor and feedback system. The airframe can be any of a variety of known configurations with multiple rotors, fixed or retractable wings, puller or pusher propellers, or jet engines. The airframe includes at least one arm that is used to intercept and disable another airborne vehicle. In some configurations, the arm is fixed and can include fingers at its outer end. In other configurations, the arm is movable from a closed condition to an open condition. A wire or net is connected between the arm and a portion of the airframe so that the wire or net is spread open when the arm is deployed to the open condition. The wire or net are configured to disable or capture a target such as another aerial vehicle. |
| US12234022B2 |
Electrical energy system for barring rotor
An example system includes an electrical machine electrically configured to generate electrical energy used by one or more components of a gas-turbine engine; an energy storage system; and a controller electrically connected to the energy storage system and configured to receive electrical energy from the energy storage system, wherein, in response to the gas-turbine engine being shut off, the controller is configured to cause the electrical machine to rotate a rotor of the gas-turbine engine using the energy received from the energy storage system. |
| US12234021B2 |
Systems and methods for improved gearboxes for evtol aircraft
The present disclosure relates generally to a method for balancing a rotor of an electrical engine of an electrical propulsion system comprising: identifying an axis of rotation of a rotor, wherein the rotor comprises a sacrificial layer having a mass M formed along a circumference of the rotor; determining an imbalance present in the rotor by rotating the rotor about the axis of rotation, wherein determining an imbalance includes marking the rotor, rotating the rotor, and detecting an amplitude of the imbalance; calculating an amount of mass k to add or remove at a position p along the sacrificial layer such that a center of mass of the rotor coincides with the axis of rotation of the rotor; and removing an amount of mass r from the sacrificial layer such that an amount of remainder mass n is present along the circumference of the rotor. |
| US12234015B2 |
Free play chatter suppression
An apparatus and method for suppressing free play chatter of a control surface of an aircraft. The free play chatter suppression apparatus includes a containment vessel connected to a control surface of an aircraft. A lossy material is contained within the containment vessel. A body is positioned within the lossy material. The deceleration of the body by the lossy fluid is transmitted to the control surface to dampen vibrations of the control surface. |
| US12233996B1 |
Underwater submersible robot and control method and control apparatus therefor
A method includes: calculating a first difference between a current actual attitude of a fuselage and a desired attitude and a second difference between an actual depth and a desired depth; inputting the first difference and the second difference into a set terminal sliding mode surface to obtain an output value of the terminal sliding mode surface; using the output value as an input of a preset high-order observer, a radial basis function neural network and a terminal sliding mode control law, respectively, and using an output of the high-order observer and an output of the radial basis function neural network as a compensation input of the terminal sliding mode control law; performing power distribution for each propeller of a propeller assembly on the basis of the virtual force to obtain a propelling force of each propeller; and controlling the propellers of the underwater submersible robot. |
| US12233994B2 |
Providing system of ship propulsive performance in actual seas
Objects of the present invention are provide an evaluation method of ship propulsive performance in actual seas, an evaluation program of ship propulsive performance in actual seas and an evaluation system of ship propulsive performance in actual seas capable of precisely evaluating ship propulsive performance in actual seas on the same scale also before the ship sails for example. As solving means of the objects, a standard sailing model 2 of the ship in actual seas is set, a sailing condition of the ship and a ship condition of the ship are input to the standard sailing model 2, the standard sailing model 2 into which the sailing condition and the ship condition are input and the ship condition are applied to a previously verified calculating method 1 of ship performance in actual seas, and ship propulsive performance in actual seas is evaluated. |
| US12233993B1 |
Floating power generation system
A floating power generation system incorporates a scotch yoke mechanism that is coupled with an electrical generator to produce power and is actuated by a fin assembly having a plurality of fins that move or pivot from a first pivot position to a second pivot position. The fins are coupled with the yoke of the scotch yoke by a cable to move the yoke back and forth in a reciprocating motion. As the fins move back and forth from one side of the water flow direction to the other, the yoke reciprocates and turns the flywheel to produce electrical power. The floating power generation system may employ two fin assemblies, wherein a first fin assembly directs water through the plurality of first fins into the plurality of second fins of the second fin assembly to force the second fins in an opposing pivot orientation from said first fins. |
| US12233981B2 |
Pannier and vehicle including the same
A pannier includes: a casing body; a lid; an attaching-detaching holder which removably attaches the casing body to the vehicle; an opening-closing holder which attaches the lid in an openable and closeable manner; a cylinder which serves to lock both of the attaching-detaching holder and the opening-closing holder; and first and second movable holders which are movable when the cylinder is unlocked. At a lock position of the cylinder, the first and second movable holders are retained at a position where the casing body is unremovable and the lid is unopenable. At a pannier detaching position off the cylinder, the second movable holder is movable to an attachable-detachable position where the movable holder allows the casing body to be detached. At a pannier opening position of the cylinder, the first movable holder is movable to an openable position where the movable holder allows the lid to be opened. |
| US12233979B2 |
Removable bass speaker enclosure for motorcycle saddlebags
A sealed speaker enclosure for a bass speaker that is hand-insertable and removable from a hard-side motorcycle saddlebag. The body of the enclosure complements the interior space of the saddlebag making sealing contact with the interior walls of the saddlebag. The bass speaker faces the motorcycle side of the saddlebag within the shock absorber tower indentation overlapping and opening. A speaker grill overlays the opening in the shock absorber tower indentation of the saddlebag. |
| US12233977B2 |
Handlebar assembly for a bicycle and accessory structure
A bottle structure for a bicycle handlebar, includes a bottle body having an integrally-formed bottle and bottle coupling structure. The bottle coupling structure is directly connected to the bicycle handlebar, and is dissociable from the bicycle handlebar. The integrated bottle structure may include additional features such as a straw structure or other devices. |
| US12233973B2 |
Steer by wire steering column assembly
A steer by wire steering column assembly for a vehicle comprises a shroud having a first shroud portion and a second shroud portion, the two shroud portions being constrained to move telescopically relative to one another for adjustment of a reach position of the steering column assembly; a shaft supported by one or more bearing assemblies housed within the shroud and adapted for supporting a handwheel or another user operable device at a free end; and a linear actuator that includes an elongate threaded rod that is connected at a first location to one of the shroud portions by a first bracket assembly and at a second location to the other shroud portion by a second bracket assembly, the linear actuator controlling the telescopic position of the shroud by causing the threaded rod to rotate around its axis. At least one of the bracket assemblies is adapted to provide a degree of lost motion between the linear actuator and the associated shroud portion that accommodates misalignment of the two shroud portions during use of the steering column assembly that would otherwise apply a bending moment to the linear actuator. |
| US12233970B2 |
Steering system based on intended yaw rate during loss of traction
Systems, methods, and other embodiments described herein relate to steering a vehicle based on an intended yaw rate during loss of traction. In one arrangement, a method for steering a vehicle during loss of traction is disclosed. The method includes detecting a slipping tire of a vehicle losing traction with a road. The method also includes decoupling control of a pair of front tires of the vehicle by a steering wheel of the vehicle. The method also includes identifying an intended yaw rate for controlling the vehicle by detecting an angle of the steering wheel while the slipping tire does not have traction. The method further includes steering the vehicle separately from an input of a steering wheel of the vehicle to cause intended yaw rate. |
| US12233966B2 |
Electric power steering device, control device for electric power steering device, and program
An electric power steering device 100 includes: an electric motor 110 configured to apply a driving force to steer a wheel in response to operation of a steering wheel; and a control device 10 configured to perform control of drive of the electric motor by estimating a degree of sloping in a transverse direction of a roadway on which a vehicle travels, determining, based on the estimated degree of sloping, a correction current for correcting a target current required for the electric motor to generate the driving force, and correcting the target current with the correction current. |
| US12233961B2 |
Steering column for a motor vehicle
A steering column may include a steering shaft that is mounted so as to be rotatable about its longitudinal axis relative to a steering column housing and a revolution limiter to limit rotation of the steering shaft. The revolution limiter has a winding core that is connected fixedly to the steering shaft for conjoint rotation therewith. A strap element may be attached to both the winding core and the steering column housing. The strap element may be elongate, may be deformable flexibly transversely with respect to its longitudinal extent, and may have a strap section that can be wound on the winding core in a winding direction around the longitudinal axis. To decrease complexity and to facilitate compactness, the winding direction of the strap section is reversible. |
| US12233955B2 |
Systems and methods for accessing motor vehicle cargo spaces
Various vehicle systems are proposed for facilitating access to and utilization of motor vehicle cargo spaces. The vehicle systems may include deployable stairgate systems, deployable step systems, cargo bed swing door systems, etc. The vehicle systems allow the cargo spaces to be accessed from a variety of positions relative to the cargo space. |
| US12233951B2 |
Reinforcement structure
A structural member (10) comprising: (i) a first carrier (12A) and a second carrier (12B), each carrier including a plurality of interconnecting ribs (16), each carrier further including one or more projections (28) extending from exterior walls (30) of each carrier; (ii) one or more secondary members (14) secured to one or more surfaces of each carrier; and (iii) an adhesive material (32) disposed on the first carrier (12A), the second carrier (12B), or both, wherein the first carrier (12A) and the second carrier (12B) are bonded to each other via the adhesive material (32). |
| US12233950B2 |
Joint structure and joining method
According to the present invention, provided are a joint structure (100) which joins a plurality of overlapped steel members (110, 120) using a connecting element (130) having a shaft portion (131), the joint structure including: a first steel member (110); and one or more of second steel members (120) overlapping the first steel member (110), in which the shaft portion (131) of the connecting element (130) is penetrated through the second steel member (120), and the shaft portion (131) of the connecting element (130) and the second steel member (120) are joined by friction welding, and the shaft portion (131) and the first steel member (110) are joined by friction welding, and a joining method for obtaining the joint structure. |
| US12233949B2 |
Vehicle skid plate comprising at least one lighting element
A vehicle skid plate comprises a skid plate body, at least one lighting element, and a plurality of fasteners. The skid plate body comprises at least a first section and a second section. The first section comprises an outer surface, an inner surface, at least one lighting aperture, a plurality of light fastening apertures, and at least one mounting aperture. Each lighting element is connected to the inner surface at a lighting aperture of the at least one lighting aperture by passing at least one fastener through an aperture in the lighting element and into a light fastening aperture. The skid plate body is configured to connect to a vehicle chassis by passing at least one fastener through a chassis aperture and into a mounting aperture. |
| US12233948B2 |
Vehicle body joint structure
An embodiment joint structure of a vehicle body includes a mount bracket attached to a side member of an underbody of the vehicle body and a supporting unit coupled to the mount bracket and to a lower part of a pillar of an upper body of the vehicle body. An embodiment vehicle includes a vehicle body including an underbody and an upper body coupled to the underbody, wherein the upper body includes a plurality of pillars extending in a vertical direction of the vehicle, a floor panel coupled to the plurality of pillars, a mount bracket attached to a side member of the underbody, and a supporting unit coupled to the mount bracket and to a lower part of a pillar of the plurality of pillars. |
| US12233944B2 |
Vehicle roof comprising a support for at least two environment sensors
A vehicle roof, in particular for a passenger car, the vehicle roof having a roof skin which forms a visible outer surface of the vehicle roof, and a sensor unit having at least two environment sensors for detecting a vehicle environment, the sensor unit being disposed below the roof skin and attached to a carrier and may have a support for the at least two environment sensors, the support being connected to a thermal management system. An electrical insulation element is disposed between each of the environment sensors and the support, the electrical insulation elements thermally coupling the respective environment sensors and the support. |
| US12233941B2 |
Body structure for vehicle having reinforcement member
A vehicle body structure includes a vehicle pillar and a unitized reinforcement member. The vehicle pillar includes an inner panel and an outer panel secured to the inner panel to form an internal cavity. The unitized reinforcement member is disposed within the internal cavity of the vehicle pillar and extends along a longitudinal direction of the vehicle pillar. The unitized reinforcement member includes an inner panel portion spaced apart from the inner panel, an outer panel portion coupled to an inner surface of the outer panel, and a connecting portion connecting the inner panel portion and the outer panel portion. |
| US12233940B2 |
Roll over protection system
A support frame assembly configured to strengthen an upper frame portion of a frame of a vehicle, comprising a first frame member having a first end and a second end, and a second frame member having a first end and a second end, wherein both the first ends of the first and second frame members are configured to couple to a front half of the frame and the second ends of the first and second frame members are configured to couple to the front half of the frame to strengthen the upper frame portion, at least one of the first and second ends of each of the first and second frame members including at least one mechanically coupled joint configured for coupling each of the first and second frame members to the front half of the frame. |
| US12233937B2 |
Vehicle subframes and methods of producing the same
Vehicle subframes and methods of producing the same are disclosed. An example apparatus includes a subframe of a vehicle including longitudinal members, and lateral extensions extending from the longitudinal members, the lateral extensions extending outward from a longitudinal centerline of the vehicle, outer edges of the lateral extensions including contours to avoid turn radii of steerable tires of the vehicle. |
| US12233933B2 |
Device for vehicles for carrying out a steering movement
Device for vehicles, in particular fork-lift trucks, the device being designed at least for carrying out a steering movement of the vehicle, the device being arranged on an arm rest of a vehicle seat of the vehicle, wherein an actuation of the device causes the steering movement, and wherein the device has a first device element arranged above the arm rest, and a second device element fixedly connected to the first device element and extending downwardly from the first device element beyond the first device element, wherein the first device element and the second device element are intended and designed for a hand to be at least partially placed thereon, wherein during a forward movement of the vehicle the hand can be at least partially placed on the first device element and during a rearward movement of the vehicle the hand can be at least partially placed on the second device element. |
| US12233930B1 |
Beach cart
A beach cart comprises a cart body, wherein the cart body comprises a push rod and a load-bearing rod; both ends of the push rod are movably sleeved with a main body support tube; a cross bar is provided between the two main body support tubes, and an inside of the cross bar is provided with a locking mechanism for adjusting the height of the push rod and locking; the locking mechanism comprises two transmission handles and a gear for driving the two transmission handles to move relative to each other or in opposite directions. The foldable support frame facilitates the user to adjust the posture of the load-bearing rod and makes loading more convenient; the cart body can also be used with the luggage to increase the carrying space and meet the user's needs. |
| US12233929B1 |
Shopping cart double handle system
A double handle shopping cart system including a shopping cart frame with a child's seat basket, with an upper rear handle for a taller shopper to hold onto and a pair of lower rear handles for a shorter shopper to hold onto. |
| US12233915B2 |
Allocating resources for a vehicle
In some examples, a system may determine a plurality of candidate routes between a source location and a destination location for a vehicle, and may segment each candidate route into multiple road segments. Further, the system may receive vehicle computing resource information and sensor configuration information for the vehicle. The system may determine that at least one of the sensor configuration or the computing resources on board the vehicle fails to satisfy a threshold associated with autonomous navigation of a road segment of a first candidate route of the plurality of candidate routes. The system may select, for the vehicle, the first candidate route based at least on determining that a computing device external to the vehicle is scheduled to perform at least one computational task for the vehicle to enable the vehicle to meet the threshold associated with autonomously navigating the road segment of the first candidate route. |
| US12233911B2 |
Autonomous yard truck for moving a trailer
Some embodiments include an autonomous yard truck that includes a speed control mechanism; a steering system; a geolocation sensor; a plurality of sensors; a fifth wheel coupling; a robotic arm disposed on the deck; an air hose with a first hose connector; a transceiver; and a controller. The controller may identify a first trailer hose connector location on a specific trailer; determine the location of a first hose connector on an autonomous yard truck; engage the first hose connector with a robotic arm; move the first hose connector from the first hose connector location to the first trailer hose connector location on the specific trailer with the robotic arm; connect the first hose connector with the first trailer hose connector; disengage the first hose connector from the robotic arm; and/or test the connection between the connection between the first hose connector and the first trailer hose connector. |
| US12233910B2 |
Indoor localization of autonomous vehicles
Devices, systems, and methods are provided for indoor localization. A self-driving vehicle may detect a first fiducial marker located at a first location within a building, wherein the first fiducial marker comprises first fiducial marker information associated with the first location. The self-driving vehicle may retrieve the first fiducial marker information from the first fiducial marker. The self-driving vehicle may generate localization information of the self-driving vehicle based on the first fiducial marker information. The self-driving vehicle may utilize the localization information to transition to a second location within the building, wherein the second location comprises a second fiducial marker. |
| US12233909B2 |
Vehicle parking assist apparatus
A vehicle parking assist apparatus acquires and registers first information on a parking lot from a camera image when a vehicle stops by the parking lot. The vehicle parking assist apparatus acquires and registers second information on the parking lot from the camera image when completing parking the vehicle in the parking lot by a parking assist control. The vehicle parking assist apparatus acquires the information on the parking lot as current parking lot information from the camera image when the vehicle stops by the parking lot after registering the first and second parking lot information and executes the parking assist control with realizing a relationship in position between the vehicle and the parking lot by comparing the current parking lot information with the registered parking lot information. |
| US12233901B2 |
Graph neural networks with vectorized object representations in autonomous vehicle systems
Techniques are discussed herein for generating and using graph neural networks (GNNs) including vectorized representations of map elements and entities within the environment of an autonomous vehicle. Various techniques may include vectorizing map data into representations of map elements, and object data representing entities in the environment of the autonomous vehicle. In some examples, the autonomous vehicle may generate and/or use a GNN representing the environment, including nodes stored as vectorized representations of map elements and entities, and edge features including the relative position and relative yaw between the objects. Machine-learning inference operations may be executed on the GNN, and the node and edge data may be extracted and decoded to predict future states of the entities in the environment. |
| US12233900B2 |
Edge system for providing local dynamic map data
Embodiments include methods performed by a processor of an Edge computing device for generating local dynamic map (LDM) data. The processor may receive new or updated (“first”) LDM data for a service area of the Edge computing device. The processor may integrate the first LDM data into an LDM data model. The processor may determine second LDM data of the LDM data model that is relevant to a vehicle or mobile device. The processor may provide the determined second LDM data to the vehicle or mobile device. |
| US12233899B2 |
Systems and methods for simulated rumble strips using fully actuating vehicle seat
System, methods, and other embodiments described herein relate to generating a response of a vehicle to a virtual rumble strip. In one embodiment, a method includes determine that a virtual boundary corresponding to a real-world location in proximity of a vehicle has been crossed as the vehicle travels based upon first sensor data generated by the vehicle. The method further includes determine information about an environment of the vehicle as the virtual boundary is crossed based upon second sensor data generated by the vehicle. The method also includes activate an actuator of a seat of the vehicle such that haptic feedback is delivered to the seat, wherein the haptic feedback is based upon the information about the environment and a type of a virtual rumble strip. |
| US12233893B2 |
Pedal system for a vehicle designed to be driven in an at least partly automated manner
A pedal system for a vehicle that is configured to be driven in an at least part-automated manner. The pedal system includes a driving pedal and a brake pedal. The pedal system is allocated a representation function between a pedal actuation and control parameters for the longitudinal control of the vehicle. The pedal system is configured so as, when the vehicle is being operated, to vary the representation function between the pedal actuation and the control parameters for the longitudinal control of the vehicle in dependence upon a variable that represents the degree of automation of the driving mode of the vehicle and at least a first condition for restricting the representation function of the pedal actuation and/or at least a second condition for eliminating the restriction of the representation unction of the pedal actuation. |
| US12233883B1 |
Systems and methods for intelligently transforming data to generate improved output data using a probabilistic multi-application network
Disclosed are systems and methods for intelligently transforming data to generate improved output data, including, for example, for use in a multi-application network with disparate parties. The systems and methods include transforming data using a probabilistic network and a knowledge base generated using historic data to generate improved output data and include the steps of receiving first data associated with a first user and associated with a first incident object. In some embodiments, the systems and methods include generating a first computing object, transmitting the first computing object, receiving a first selection, transmitting a data collection computing input tool, receiving a second selection, receiving second data comprising a first image of a first incident object, transmitting the second data, transforming the second data using a probabilistic network, a machine learning model, a knowledge base, and a data group associated with patterns of processed historic data, and generating improved output data. |
| US12233882B2 |
Control system for vehicle powertrain during off-road jumping
A vehicle includes at least one drive wheel, a powerplant, a clutch, and a controller. The powerplant is configured to generate and deliver power to the at least one drive wheel. The clutch is disposed between the at least one drive wheel and the powerplant. The controller is programmed to, in response to detecting the at least one drive wheel disengaging the ground during a vehicle jump, open the clutch to disconnect the at least one drive wheel from the powerplant. |
| US12233880B2 |
Methods and systems for information recommendation
The embodiments of the present disclosure may disclose methods and systems for information recommendation. The method for information recommendation method may include: determining a violation count corresponding to a violation behavior in historical driving behavior of a driver; determining, based on the violation behavior and its corresponding violation count, information to be recommended; and sending the information to be recommended to a driver terminal of the driver. |
| US12233879B2 |
Vehicle-interior monitoring apparatus
A vehicle-interior monitoring apparatus for a vehicle includes a millimeter-wave sensor, a determiner, and a movement sensor. The millimeter-wave sensor outputs a millimeter radio wave toward a vehicle cabin of the vehicle and detects a millimeter reflection wave from an in-vehicle object including either one of an occupant and baggage in the vehicle cabin. The determiner determines a type of the in-vehicle object based on a detection level of the detected millimeter reflection wave. The movement sensor detects movement of the vehicle. The determiner re-determines that a determined in-vehicle object is either one of the baggage and a child as the occupant based on a positional change of the determined in-vehicle object upon the movement sensor detecting the movement of the vehicle, the determined in-vehicle object being the in-vehicle object of which the determiner has determined the type based on the detection level of the millimeter reflection wave. |
| US12233878B2 |
Enhanced rider pairing for autonomous vehicles
Devices, systems, and methods are provided for enhanced rider pairing of an autonomous vehicle (AV). A system may pair a first user profile of a first user located at a first location with a first autonomous vehicle (AV) to complete a trip to a destination selected by the first user. The system may detect a second AV at the first location, wherein the second AV is associated with a second user profile. The system may connect the second AV with the first user using a connection mechanism. The system may select a profile status of the first user profile based on the connection to the second AV. The system may pair the first user profile with the second AV based on the profile status. |
| US12233871B1 |
Vehicle gear selection control
A motor vehicle for operation by a driver has a frame with wheels and a motor connected to the frame. A steering control is connected to the wheels to establish a steering angle. A controller is operably connected to the steering control, to the motor, and to the wheels, and is operable to selectably drive the wheels in a forward direction in a drive mode and in a rearward direction in a reverse mode. The controller is operable to select a direction for driving the wheels in response to a pattern of steering angle movements, without operator indication of a direction. |
| US12233870B2 |
Vehicle driving assistance apparatus
A vehicle driving assistance apparatus includes a traveling environment recognizer and an adaptive cruise controller. The traveling environment recognizer recognizes traveling environment information regarding an outside of a vehicle. Based on the traveling environment information, the adaptive cruise controller performs a follow-up traveling control of causing the vehicle to travel to follow a preceding vehicle, if recognized, and performs a constant-speed traveling control of causing the vehicle to travel at constant speed. If the vehicle starts a lane change to a traveling lane during traveling based on the follow-up traveling control, the adaptive cruise controller keeps a target vehicle speed at a start of the lane change at least until the lane change ends, and thereafter accelerates the vehicle, by setting a set vehicle speed as a new target vehicle speed, and setting a target acceleration rate based on the new target vehicle speed. |
| US12233866B2 |
Vehicle control device, vehicle control method, and non-transitory computer-readable recording medium recording program
A vehicle control device includes: a recognition part recognizing a first road marking line on a first side of a lane traveled by a vehicle; an obtaining part obtaining information on a second road marking line on the first side of the lane from map information; and a support part that executes a support processing for preventing the vehicle from deviating from a road marking line when a probability that the vehicle deviates from the road marking line is greater than or equal to a predetermined degree. When a degree of matching between a first position of the first road marking line and a second position of the second road marking line is less than or equal to a first threshold value, the support part suppresses execution of the support processing for preventing the vehicle from deviating from a road marking line on the first side. |
| US12233865B2 |
Preceding vehicle selection device, preceding vehicle selection method, and non-transitory recording medium
The preceding vehicle selection device includes a processor configured to estimate a continuous running distance from a present time of a surrounding vehicle based on information relating to the surrounding vehicle for each of a plurality of surrounding vehicles, estimate a followable distance when the host vehicle follows the surrounding vehicle based on the continuous running distance from the present time of the surrounding vehicle for each of the plurality of surrounding vehicles, and select the preceding vehicle from among the plurality of surrounding vehicles based on the followable distance. The information relating to the surrounding vehicle includes at least one of an SOC or an amount of remaining fuel of the surrounding vehicle, and a continuous running time or a continuous running distance up to the present time of the surrounding vehicle. |
| US12233862B2 |
Driver assistance device to be applied to vehicle at times of right- and left-hand turns
A driver assistance device acquires information about vehicle-driving environment ahead of the vehicle to detect an intersection. Upon determining that the vehicle makes a right- or left-hand turn at the intersection, the driver assistance device sets a projected course of the vehicle and recognizes a moving object ahead in a direction in which the vehicle making a right- or left-hand turn is headed. The driver assistance device calculates a movement vector from positional changes of the moving object to calculate a meeting point of a path of the object and the projected course. When an interval between times at which the vehicle and the moving object reach the meeting point is found to fall within a predetermined range, the driver assistance device determines that there is a possibility of interference between the vehicle and the moving object and then causes the vehicle to halt short of the meeting point. |
| US12233861B2 |
Object recognition apparatus and non-transitory recording medium
An object recognition apparatus includes at least one processor and at least one memory communicably coupled to the processor. The processor sets one or more object presence regions in each of which an object is likely to be present, on the basis of observation data of a distance sensor. The processor estimates an attribute of the object that is likely to be present in each of the one or more object presence regions. The processor sets, on the basis of the attribute of the object, a level of processing load to be spent on object recognition processing to be executed for each of the one or more object presence regions by using at least image data generated by an imaging device. The processor performs, for each of the one or more object presence regions, the object recognition processing corresponding to the set level of the processing load. |
| US12233858B2 |
Trailer monitoring system
A trailer monitoring system for a vehicle includes a processor and a memory communicably coupled to the processor. The memory stores instructions that when executed by the processor cause the processor to receive, from at least one monocular camera mounted to a vehicle towing a trailer, at least one monocular camera image of at least a portion of the trailer. The instructions also cause the processor to generate at least one depth map based on the at least one monocular camera image. The instructions further cause the processor to identify a trailer irregularity based on the at least one depth map. |
| US12233857B2 |
Obstacle avoidance for vehicle
A computer includes a processor and a memory, the memory storing instructions executable by the processor to receive sensor data indicating an obstacle, formulate a control barrier function for a vehicle based on the sensor data, determine a control input based on the control barrier function, and actuate a component of the vehicle according to the control input. The control barrier function is defined with respect to a reference point that is spaced from a centroid of the vehicle. |
| US12233855B2 |
Motion manager, vehicle, vehicle control method, and non-transitory storage medium
A motion manager configured to request motion of a vehicle according to a kinematic plan on driver assistance of the vehicle to at least one of a plurality of actuators provided in the vehicle includes one or more processors. The one or more processors are configured to receive information indicating a plurality of kinematic plans and classify the information into predetermined items such that a realization method of achieving a purpose of each of the kinematic plans is selectable without specifying or distinguishing a setting source of each of the kinematic plans, arbitrate the kinematic plans, calculate a motion request to the vehicle based on a result of arbitrating the kinematic plans, and distribute the motion request to at least one of the actuators. |
| US12233851B2 |
Plug-in electric vehicles with derated traction control upon system faults
A method for controlling the distribution of power to a traction motor in a plug-in electric vehicle having a plurality of on-board sources of electric power. Power is distributed at a normal power control relationship in response to an operator control input during operation in a normal mode. Power is depleted at a first rate during operation of the vehicle in the normal mode. Power is distributed at a derate power control relationship in response to the operator control input during operation in a derate mode. Power is depleted at a second rate that is less than the first rate during operation in the derate mode to conserve the power of the one or more on-board sources. Operation in the derate mode can be initiated in response to information from sensors identifying a vehicle condition indicating a battery charge limitation. |
| US12233848B2 |
Controls and methods to calculate clutch torque to include seal friction
A hybrid vehicle includes an engine, an electric machine, a disconnect clutch configured to selectively couple the engine to the electric machine, and a controller. The controller is programmed to, in response to a request to start the engine with the electric machine, command a target pressure to the disconnect clutch that depends on a seal friction derived from a measured line pressure of the disconnect clutch and a rate change of the measured line pressure. |
| US12233847B2 |
System and method of vehicle powertrain control
An efficiency-based powertrain control system and method to provide real-time optimization of powertrain efficiency for a plug-in hybrid electric vehicle (PHEV). |
| US12233846B2 |
Hybrid vehicle control device
Provided is a hybrid vehicle control device excellent in quietness while suppressing knocking within an allowable limit. The hybrid vehicle control device of an aspect of the invention is a hybrid vehicle control device that controls a hybrid vehicle including a motor that drives wheels, a generator that supplies electric power to the motor, and an engine configured by an internal combustion engine that drives the generator, and includes a control unit that calculates a knock index value indicating a knock degree of the engine at an engine operating point represented by a relationship between an engine rotational speed and an engine torque, and controls the engine rotational speed and the engine torque based on the knock index value. As the knock index value decreases, the control unit sets the target engine rotation speed to be lower and the target engine torque to be higher in the target power generation amount. |
| US12233844B2 |
Method for controlling interference torque, controller, equipment and medium
A method for controlling an interference torque for a vehicle is provided. The method is applied to a new energy vehicle including an electric motor and an engine, and includes steps of: arbitrating between a pedal torque of a driver and an interference torque required by ESP; performing an initial allocation on the electric motor and/or the engine in response to the pedal torque when the vehicle is in a hybrid drive mode, to meet an engine torque request while ensuring that the engine is operated at an optimal operation point; and determining, based on the initial allocation, whether the motor is capable of fully responding to the arbitrated torque, if so, controlling the motor to respond to the arbitrated torque in priority, otherwise controlling the engine and the motor to cooperatively respond to the arbitrated torque. |
| US12233842B2 |
Vehicle behavior control method
A vehicle behavior control method is suitable for a vehicle behavior control device. The vehicle behavior control device includes: a lateral acceleration sensor, detecting lateral acceleration occurring in a vehicle body; a wheel speed sensor, detecting a wheel speed of a wheel; a steering angle sensor, detecting a steering angle of the wheel; a steering angle lateral acceleration calculation unit, calculating steering angle lateral acceleration from the wheel speed and the steering angle; and a yaw moment control unit, applying yaw moment to the vehicle body. In the vehicle behavior control method, when the lateral acceleration and the steering angle lateral acceleration meet a predetermined condition, a yaw moment directed inward in a turning direction of the vehicle body is applied by the yaw moment control unit. |
| US12233839B2 |
Redundancy based electric brake failure detection method and device using the same
A motor control device is provided which achieves redundancy while suppressing an increase in the number of parts and connection signal lines. The device includes angle sensors for detecting a rotation angle of a motor, a first microcomputer unit for controlling the motor based on a stroke sensor and receiving the detected value of the angle sensor, a second microcomputer unit for controlling the motor based on the stroke sensor and receiving the detected value of the angle sensor, and communication units for transmitting and receiving signals between the microcomputer units. The first microcomputer unit includes an angle sensor failure detecting unit for detecting a failure of the angle sensors, according to the detected value of the angle sensors, and a control angle of the motor created in response to the stroke sensor. |
| US12233836B2 |
Braking control device for vehicle
A braking control device includes a braking control unit that controls a braking device, a load reduction amount derivation unit that derives a reduction amount of a load input from a vehicle body to a suspension for a second wheel, and an anti-force derivation unit that derives an anti-lift force. The braking control unit performs posture braking processing of adjusting the second braking force so that the difference between the reduction amount of the load and the anti-lift force is less than or equal to a difference determination value, and adjusting the first braking force so that the vehicle braking force becomes the required value. |
| US12233834B2 |
Vehicle control device, vehicle control method, and storage medium
A vehicle control device includes: a recognizer configured to recognize a surrounding situation of a host vehicle; an input unit configured to receive an input operation from an occupant of the host vehicle; a controller configured to perform automatic stop control of decelerating and stopping the host vehicle when the input operation is received by the input unit; and a setter configured to perform a setting process of setting a first time after the input operation has been received by the input unit and until the automatic stop control is started by the controller. The setter is configured to change the first time based on a result of recognition of a following vehicle of the host vehicle from the recognizer in the setting process. |
| US12233833B2 |
Braking assist control device, braking assist system, and braking assist control method for vehicle
A braking assist control device for a vehicle including a detector and a braking assist control device is provided. The braking assist control device includes an acquisition unit configured to acquire information on an ambient environment of an own vehicle from the detector, and a control unit configured to cause the braking assist device to perform intersection entry prevention assist in a case where it is determined, using the acquired information on the ambient environment, that the own vehicle is approaching an intersection and an own lane in which the own vehicle is traveling is a non-priority lane with respect to an intersecting lane. |
| US12233827B2 |
Electronic brake system
Disclosed herein an electronic brake system includes a reservoir provided with spaces for storing oil, the spaces configured to be partitioned; a master cylinder connected to the reservoir, the master cylinder including first and second master chambers and first and second pistons provided in each master chamber, to discharge oil according to a pedal effort of a brake pedal; a hydraulic pressure supply device operated by an electrical signal to generate hydraulic pressure and including first and second pressure chambers and a hydraulic piston; a first hydraulic circuit configured to transmit hydraulic pressure discharged from the hydraulic pressure supply device to wheel cylinders of left front and right front wheels; and a second hydraulic circuit configured to transmit hydraulic pressure discharged from the hydraulic pressure supply device to wheel cylinders of left rear and right rear wheels; wherein hydraulic pressure returned from the wheel cylinders and hydraulic pressure returned from the second pressure chamber flow into the same reservoir chamber. |
| US12233821B2 |
Vehicle cleaner unit and vehicle cleaner system
A vehicle cleaner unit is configured to clean a cleaning object mounted near a bumper or a grille of a vehicle. The vehicle cleaner unit includes a blower configured to be attached to a rear surface of the bumper or the grille. The bumper or the grille is provided with an air outlet for jetting air blown from the blower toward the cleaning object. |
| US12233816B2 |
Locking boot for vehicle wheel
A vehicle locking boot includes a horizontal support arm and a first vertical support arm extending from the horizontal support arm. The first vertical support arm includes a front engagement protrusion. A receiving sleeve extends from the horizontal support arm at a base of the first vertical support arm. A horizontal extension portion is coupled to the horizontal support arm. A second vertical support arm extends from the horizontal extension portion. The second vertical support arm includes a rear engagement protrusion extending therefrom. The front engagement protrusion faces the rear engagement protrusion. A keypad is disposed on the first engagement portion to lock and unlock the horizontal extension portion. A lug nut blocking plate is coupled to the first vertical support arm. A global positioning system (GPS) housing is positioned at an upper portion of the first vertical support arm. |
| US12233815B1 |
Vehicle securement assembly and method for monitoring vehicle securement assemblies
A retractable securement assembly, including a frame, a shaft rotatably connected to the frame, the shaft including a first end and a second end, a spring assembly connected to the first end, the spring assembly operatively arranged to bias the shaft in a first circumferential direction, a line connected to the shaft and arranged to form a coil around the shaft in a fully retracted state, and an electronics assembly, including a plate non-rotatably connected to the second end, and a circuit operatively arranged proximate the plate to retrieve information about the shaft or the line and send the information to a remote location. |
| US12233810B2 |
Occupant protection device
An occupant protection device for a vehicle includes a first bag that deploys in front of a vehicle's occupant, a second bag that deploys adjacent to the first bag, and a deployment controller that selects, according to a collision mode, a first deployment mode in which the first bag deploys and the second bag does not deploy and a second deployment mode in which both bags deploy. The first bag includes a first air chamber, a second air chamber that extends from the first air chamber toward the second bag, and a communication flow path that supplies deployment gas from the first air chamber to the second air chamber. The communication flow path includes a supply restriction unit that restricts supply of the deployment gas from the first air chamber to the second air chamber in response to interference between the second air chamber and the second bag. |
| US12233806B2 |
Airbag apparatus
An airbag apparatus includes a far-side airbag and an expansion control processor controlling expansion of the far-side airbag. The far-side airbag is a cylindrical base fabric member, has an annular outer periphery, and has a shoulder protection air chamber, a head protection air chamber, and a non-inflating unit in an inner periphery. The shoulder protection air chamber is expanded into a longitudinal cylindrical shape to protect a shoulder of an occupant seated in a vehicle front seat. The head protection air chamber is expanded into a semicircular shape and falls against the occupant to protect the occupant's head. The non-inflating unit is disposed adjacent to the back shoulder air chamber and includes an inflator covered with a cylinder. The far-side airbag has a gas passage through which high-pressure gas discharged from discharge ports of the cylinder are fed to the shoulder protection air chamber and the head protection air chamber. |
| US12233805B2 |
Method for securing a passenger in a motor vehicle, and motor vehicle
A motor vehicle and a method secure a passenger in the motor vehicle in a collision. The motor vehicle has a seat including a seat body, which forms a seat surface, and a backrest connected to the seat body. An inertial force acting on the passenger in a collision is transmitted by a seatbelt arrangement to the backrest in such a manner that the latter pivots forwards relative to the seat body counter to the restoring effect of an elastic and/or plastic deformation of at least part of the backrest. A force which counteracts the pivoting-forwards action is generated by a force generator, and transmitted to the backrest, and/or the maximum pivoting path of the backrest is limited by a limiting device in that, when a predetermined reference acceleration is present, a deviation between a present pivoting path of the backrest and a predetermined reference pivoting path is minimized. |
| US12233799B1 |
Vehicle skid plate
A planar skid plate (1) having specially placed slits (11) that allow the skid plate to conform and seal to three-dimensional contours of a vehicle's exterior surface when pressed against vehicle's exterior surface. The skid plate may be removed without causing damage to the existing finish of the vehicle and without leaving any signs it was ever installed on the vehicle. |
| US12233798B2 |
Vehicle front structure
A vehicle front structure includes side frames in pairs, a bumper beam, lower frames in pairs, and a lower beam. The lower beam extends in a vehicle width direction on a vehicle lower side of the bumper beam. The lower beam is coupled to vehicle-front-side end parts of the lower frames. The lower beam includes a front lower beam member and lower beam members in pairs. The front lower beam member constitutes a vehicle-front-side part of the lower beam. The front lower beam member extends in the vehicle width direction. Longitudinal-direction end parts of the front lower beam member are disposed outward in the vehicle width direction, as seen from the lower frames. The rear lower beam members constitute a vehicle-rear-side part of the lower beam. The rear lower beam members are joined respectively to both of the longitudinal-direction end parts of the front lower beam member. |
| US12233795B2 |
Vehicle-electric vehicle supply equipment connection confirmation
A vehicle includes control pilot circuitry connected with a charge port and including a control pilot line, a resistor, and a switch that selectively connects the resistor between the control pilot line and a ground of electric vehicle supply equipment plugged into the charge port. The vehicle also includes a controller that toggles the switch between open and closed states after receiving an off-board request defining a number of toggles for the switch. |
| US12233792B2 |
In-vehicle device and control method
An in-vehicle device that provides a predetermined function to a passenger of a vehicle, the in-vehicle device comprises an operation element that is a hardware interface; and a controller comprising at least one processor configured to perform output a signal for supplying power to an accessory power supply system of the vehicle, in a case where operation is performed on the operation element. |
| US12233788B2 |
Control apparatus
A control apparatus includes a processor that determines whether an ice generation condition is satisfied on the basis of at least one or both of a state of a heat source of a vehicle and an outside air temperature after an operation stop of a drive source of the vehicle. If the ice generation condition is satisfied, the processor repeats an ice-crushing operation at a predetermined time interval in a predetermine ice-crushing time period by turning on and thereafter turning off the relay. The predetermined ice-crushing time period is determined on the basis of a temperature difference between a temperature of the fixed contact or the movable contact of the relay and a temperature of an internal atmosphere inside the relay. The predetermined time interval is a time period in which the ice on the fixed contact and the movable contact of the relay grows to a predetermined size. |
| US12233773B2 |
Exterior light structure for vehicle
An exterior light structure is mounted in a vehicle including fender members and a hood member. The fender members are disposed in side parts of a vehicle body. The hood member is disposed adjacent to upper parts of the fender members. The exterior light structure includes lamp bodies 22. The lamp bodies 22 are disposed between the upper parts of the fender members and side edge parts of the hood member substantially in a vehicle body forward-rearward direction. The lamp bodies 22 radiate light to the outside of the vehicle through gaps d between the fender members and the hood member. |
| US12233770B2 |
Wheel chock device and method of forming
A vehicle chock device includes a first body portion and a stepped-box body integrally formed with the first body portion. The stepped-box body has a lower portion and an upper portion. The stepped-box body transitions from a first generally planar, generally horizontal surface on the lower portion to an intermediate sloped surface to a generally planar, generally vertical surface on the upper portion. The lower portion has a second generally planar, generally horizontal surface configured to engage a supporting surface of a carrier vehicle on which an automobile is disposed. An opposite side of the upper portion that is opposite the generally planar, generally vertical surface defines a tire-contacting surface that is positioned to engage a vehicle tire of the automobile while the second generally planar, generally horizontal surface engages the supporting surface of the carrier vehicle. |
| US12233765B2 |
Kinetic seat cushions for vehicles
A kinetic seat cushion assembly that rotates based on a force applied on an occupant seated therein is provided. The kinetic seat cushion assembly includes a primary seat cushion frame, a secondary seat cushion frame, a seat cushion tilt mechanism coupling the secondary seat cushion frame to the primary seat cushion frame such that the secondary seat cushion frame is movable with respect to the primary seat cushion frame, and a front pivot mechanism that pivotally couples a front portion of the primary seat cushion frame to a front portion of the secondary seat cushion frame. |
| US12233763B2 |
Energy absorbing device for vehicle seat
An assembly includes a vehicle floor. The assembly includes a seat including a pedestal supported by the vehicle floor. The assembly includes a track supported by the vehicle floor. The pedestal is slidable along the track. The assembly includes an energy absorbing device supported by and slidable along the track. The energy absorbing device is between the track and the pedestal. The energy absorbing device is deformable relative to the track. |
| US12233761B2 |
Cargo partition locking apparatus for a vehicle
A cargo locking system for a vehicle, the cargo locking system includes a gate and a pivot bracket coupled with the gate. The cargo locking system also includes a latch radially extending from the pivot bracket. The latch is movable between a first position and a second position. The cargo locking system also includes an actuator coupled with the latch. The cargo locking system further includes a striker coupled with the gate. The striker is movable between an unlocked position and a locked position. The striker holds the latch in the first position when the striker is in the locked position. |
| US12233760B2 |
Vehicle systems including stowable and deployable vehicle motion controller
In at least some implementations, a motion control system for a vehicle includes a steering shaft having an axis of rotation and a motion control input coupled to the steering shaft for rotation with the steering shaft about the axis of rotation. The motion control input is pivotable about a pivot axis that is at a non-zero angle to the axis of rotation, and wherein pivoted movement of the motion control input about the pivot axis in a first direction causes a forward motion of the vehicle, and pivoted movement of the motion control input about the pivot axis in a second direction that is opposite to the first direction reduces a speed of forward motion of the vehicle. |
| US12233759B2 |
Rotatable car seat with detachable seat and top anchor
A child safety seat for use in a vehicle, the safety seat having a base including a rotating mechanism and a seat shell for a child that is detachably connectable to the base. The base is anchorable in the vehicle using either conventional safety belts or LATCH anchoring provisions. The base is configured to allow a conventional three-point occupant restraint to secure the base to the vehicle and to prevent interaction between the seat shell and the restraint belt. The seat shell, when connected to the base, may be rotated about a generally upstanding axis into forward-facing, rearward-facing, or side-facing configurations. The base includes a moveable wedge that allows the base to optimally fit a variety of vehicle seat having different seat cushion inclinations. The seat shell also includes a height-adjustable backrest portion that allows the seat configuration to be optimized for the occupant, even as the occupant child grows. |
| US12233756B2 |
Track system with a support member
A support assembly may be configured for connections with, adjustment along, and removal from a track assembly. The support assembly may include a support member and/or an electrical connector. The electrical connector may be adjustably connected to the support member and adjustable to a first position and a second position relative to the support member. The electrical connector may include a first contact configured to engage a first conductor of said track assembly. The first contact may be engageable with said first conductor when the electrical connector is in the first position. The electrical connector may be configured such that the first contact is disposed at a distance from said first conductor when the electrical connector is in the second position. The first contact may be movably connected to the electrical connector such that the first contact is movable relative to the electrical connector and the support member. |
| US12233749B2 |
Electrified vehicle configured to identify battery condition by classifying data set
This disclosure relates to an electrified vehicle configured to identify a battery condition, such as a thermal event and/or an open circuit event, by classifying a data set, and a corresponding method. In some aspects, the techniques described herein relate to an electrified vehicle, including: a battery pack; a sensor configured to generate signals indicative of a property of the battery pack; and a computing system including a controller and a classification model, wherein the controller is configured to interpret the signals from the sensor to obtain a data set corresponding to the properties of the battery pack over a period of time, and wherein the controller is configured to use the classification model to classify the data set as a thermal event. |
| US12233748B2 |
Multi-voltage vehicle operation
A vehicle includes two or more battery packs configured to power a motor. A controller is configured to dynamically activate an operational mode during operation. The operational mode is one of multiple possible operational modes including a first operational mode defining a series connection between the two or more battery packs and second operational mode defining a parallel connection between the two or more battery packs. The connection between the battery packs is controlled by a first plurality of switches. A plurality of low voltage loads are connected to a subset of the battery packs in the battery packs such that a power output of the subset of the battery packs provides full power to the plurality of low voltage loads. The plurality of low voltage loads are connected to only the subset of the battery packs in both the first operational mode and the second operational mode. |
| US12233744B2 |
Charging system for a vehicle
A vehicle includes a battery, an electric machine, an electrical port, sensors, and a controller. The battery is configured to store electrical power. The electric machine is configured to receive electrical power from the battery to propel the vehicle. The electrical port is configured to receive an electrical connector of a charging station to initiate a charging operation of the battery. The sensors are configured to monitor an exterior of the vehicle. The controller is programmed to, in response to the sensors detecting an unidentified individual approaching the vehicle, eject the electrical connector from the electrical port or enable full operation of the vehicle. |
| US12233742B2 |
Electric vehicle supply equipment
Electric vehicle supply equipment includes at least first and second connectors, and a controller. The controller, responsive to detecting the first and second connectors are engaged with first and second vehicles respectively, synchronizes electric power from the first and second vehicles and supplies the electric power to an entity other than the first and second vehicles. |
| US12233740B2 |
Machine learning for optimization of power distribution to electric vehicle charging ports
An approach is provided for dynamically controlling power distribution amongst a plurality of charging station ports based on one or more objectives. A method includes obtaining input data, wherein the input data includes at least one of: user data associated with one or more current charging station users, or non-user data that is not associated with the current charging station users. The method includes processing the input data through one or more machine learning engines, wherein the one or more machine learning engines are trained to determine a particular power distribution, among the plurality of charging station ports, that achieves one or more objectives. The method includes configuring the plurality of charging station ports according to the particular power distribution. The particular power distribution specifies a maximum charging rate or a percentage of a power budget for each of the plurality of charging station ports. |
| US12233739B2 |
Charger peak power optimization for fleet depot
A system for charging electric vehicles is disclosed, comprising: vehicle chargers coupled to an electric power grid; and a controller in communication with the chargers and vehicles and configured to execute software to cause the controller to: determine characteristics of each vehicle, the characteristics including a charge capacity of a battery system of each vehicle and a mission schedule; determine characteristics of each charger, the characteristics including a type of each charger and a charging capacity; process the characteristics of each vehicle and each charger to identify charging opportunities for each vehicle over the course of a time period; and perform a peak power optimization analysis to generate a vehicle charging profile configured to activate a minimum number of chargers simultaneously and to minimize downtimes of the plurality of chargers to thereby distribute the power demand from the electric power grid and result in an initial peak power demand. |
| US12233738B2 |
Battery preconditioning systems and methods for electric-drive vehicles
Presented are closed-loop feedback control systems for preconditioning batteries, methods for making/using such systems, and electric-drive vehicles with battery preconditioning capabilities. A method for operating a battery system of a motor vehicle includes a system controller receiving a recharge signal to schedule a recharge event for a battery of the vehicle. The system controller responsively derives a target preconditioning temperature for optimizing the battery recharge event, and determines the battery state of voltage or charge for at the vehicle's current location. The system controller also predicts an SOV/SOC for the battery upon arrival of the motor vehicle at a selected charging station, and estimates a preconditioning time to thermally precondition the battery to the target preconditioning temperature. The system controller then transmits one or more preconditioning signals to the thermal system to precondition the battery based at least upon the present SOV/SOC, target preconditioning temperature, and predicted battery preconditioning time. |
| US12233735B2 |
Customizable electric vehicle supply equipment systems
Customizable electric vehicle supply equipment (EVSE) systems may be utilized for charging electrified vehicles. Exemplary EVSE systems may include a charging cord assembly having a cable that includes an outer sheath and a lighting module housed within the outer sheath. The lighting module may be controlled to emit lighting effects for providing visual indications of various electrified vehicle charging statuses. Settings associated with the lighting effects may be customized within a human machine interface (HMI) of the EVSE system. |
| US12233732B2 |
Customized electric vehicle charger
An electric vehicle (EV) charger includes a disconnect switch assembly including an EV connector structured to be inserted into a power receptacle for an EV, an EV charging cord coupled to the EV connector, and a disconnect switch box including a disconnect switch structured to connect or disconnect power supply to the EV and a terminal block structured to connect communications lines, where the disconnect switch box is structured to be installed at a charging space for the EV; and an EV circuit breaker charger couplable to the disconnect switch box via a separate EV charging cord and structured to be inserted within a panelboard remotely located from the charging space, the EV circuit breaker charger including a circuit interrupter structured to interrupt current from flowing to the EV in an event of fault, an EV charger structured to supply power to the EV, and a communications component structured to communicate with the EV via the communications lines. |
| US12233728B2 |
Conveyor arrangement for aerial vehicles
A conveyor arrangement for airborne battery replacement between an aerial supply vehicle having a store of replacement batteries suitable to power electric aerial vehicles and an electric aerial vehicle powered by a set of replaceable batteries is disclosed. The conveyor arrangement is configured to convey batteries between the aerial supply vehicle and the electric aerial vehicle during flight to replace a replaceable battery from the set of the electric aerial vehicle by a replacement battery from the store of the aerial supply vehicle. |
| US12233726B2 |
Charging control device
A charging control device includes an acquirer, a first deriver, a second deriver, and an executer. The acquirer is configured to acquire battery information regarding a battery. The first deriver is configured to derive an estimated charging time estimated as time to be taken to charge the battery in external charging of the battery. The estimated charging time is derived based on the battery information. The second deriver is configured to derive a difference time between the estimated charging time and a set charging time set as time for which the external charging of the battery is to be performed. The executer is configured to perform the external charging of the battery such that the battery is to be cooled throughout the difference time and the battery is to be charged throughout the estimated charging time. |
| US12233722B2 |
Battery safety alert system
A battery safety alert system includes a detection device and a controller communicatively connected to the detection device. The detection device is configured to detect position information of an engagement mechanism provided at one of a battery and a battery mounting member. A matching mechanism is provided at another one of the battery and the battery mounting member. The engagement mechanism is configured to engage with the matching mechanism to fix the battery to the battery mounting member. The controller is configured to receive the position information, determine whether the engagement mechanism is fully engaged with the matching mechanism based on the position information, and send out alarm information in response to the engagement mechanism not being fully engaged with the matching mechanism. |
| US12233719B2 |
Vehicle configured to enter a battery save mode when in a known extended parking location
The techniques described herein relate to a motor vehicle, including: a battery pack electrically connected to an electric machine and a plurality of electrical loads, wherein the motor vehicle is operable in a full power mode in which power can flow from the battery pack to the electric machine and each of the plurality of electrical loads, and a battery save mode in which a flow of power is prevented between the battery pack and either or both of the electric machine or at least some of the plurality of electrical loads; and a controller configured to command the motor vehicle to operate in the battery save mode if the motor vehicle has been parked in a known extended parking location for a first time period, or if the motor vehicle has been parked in a location other than a known extended parking location for a second time period longer than the first time period. |
| US12233717B2 |
Control device
A control device for a vehicle is provided with: two drive devices; a first speed reducer that transmits the torque of one drive device to an output shaft; and a second speed reducer that transmits the torque of the other drive device to the output shaft. The control device is provided with a torque control unit that controls, according to a target torque, the torque output by the two drive devices. The torque control unit includes a restriction unit that controls the torque output by the two drive devices when the sign of the target torque is changed from a first sign to a second sign. While outputting torque that reduces the backlash of the first speed reducer or the second speed reducer to one of the drive devices, the restriction unit outputs torque according to the target torque to the other drive device. |
| US12233715B2 |
Method and device for controlling display on basis of driving context
Methods and devices are provided for use in a vehicle. Driving information of the vehicle is obtained. The driving information includes transmission state information of the vehicle and information for an autonomous driving function. When the transmission state information indicates a position other than drive, a size of an exposed region of a first display is controlled to be a first size. When the transmission state information indicates drive and the driving information indicates that the autonomous driving function is enabled, the exposed region of the first display is controlled to be a second size that is less than the first size. When the transmission state information indicates drive and the driving information indicates that the autonomous driving function is disabled, the exposed region of the first display is controlled to be less than the second size. |
| US12233710B2 |
Drive device
The drive device comprises first and second motors comprising respective first and second rotary shafts. The drive device comprises first and second counter shafts connected to each of the first and second rotary shafts via first and second counter gears. The drive device comprises first and second transmission shafts connected to each of the first and second counter shafts via third and fourth counter gears. The drive device comprises first and second drive shafts connected to each of the first and second transmission shafts via first and second hypoid gears. The first and second rotary shafts are located between the first and second counter shafts with respect to the vehicle width direction. The first and second transmission shafts are located between the first and second counter shafts in the vehicle width direction. |
| US12233709B2 |
Fuel type identifying gas cap
A fuel type identifying gas cap that is configured to being operably coupled to an opening of a gas can and provide identification of the fuel type and a fuel to oil ratio of the fuel disposed in the gas can. The present invention includes a body wherein the body includes a top portion. The top portion includes an inner dial member being configured to display the fuel to oil ratio of the fuel disposed in the gas can. An outer dial member is present and is configured to display the fuel type, specifically indicating the octane level. A center portion is present in the body that is releasably secured thereto. The center portion is configured to display the month and year of the fuel deposit into the gas can. Additionally, the center portion is releasably secured in order to facilitate an operable coupling with a spout. |
| US12233707B2 |
Fuel device assemblies, valve assemblies, and vehicles including same
A valve assembly includes a case, a bottom cap provided at a lower end of the case, a lower float provided within an open interior of the case, an upper float provided within the open interior of the case between the lower float and the upper end of the case, and a biasing member biasing the lower float and the upper float toward the upper end of the case. The lower float includes a canister having an upper end and a rim extending from the upper end of the canister. A pair of openings is formed within the rim adjacent the upper end of the canister and partially defined by a curvilinear edge. The upper float includes a pair of legs, each leg received within a corresponding opening. |
| US12233705B2 |
Hybrid all-terrain vehicle
A hybrid all-terrain vehicle includes an engine and a motor, the engine being configured to drive the motor or output power, the motor being configured to generate electric energy or output power; the motor defining a motor cooling channel; a motor radiator including a motor radiator liquid inlet and a motor radiator liquid outlet, the motor radiator liquid inlet, the motor cooling channel, and the motor radiator liquid outlet being communicated to form a motor cooling system; and a water pump connected in the motor cooling system, a height of the water pump from the ground being less than or equal to heights of two ends of the motor cooling channel from the ground; and/or the height of the water pump from the ground being less than or equal to heights of the motor radiator liquid inlet and the motor radiator liquid outlet from the ground. |
| US12233701B2 |
Structural assembly and vehicle having structural assembly
A structural assembly for an electric vehicle includes a vehicle frame and a battery structure. The vehicle frame is distinct from a vehicle body and includes a front section, a rear section and a mid-section disposed between the front and rear sections. The mid-section includes opposed longitudinal rails. The battery structure is configured to house power storage units and is disposed between the opposed longitudinal rails. The battery structure includes a battery housing secured to the opposed longitudinal rails of the mid-section. The mid-section and the battery housing are combined into a unitized structure that is removably secured to the front and rear sections of the vehicle frame. |
| US12233696B2 |
Power line routing structure in hybrid vehicle
On a lower side of a floor (2), a battery storage section (31) is formed on a front side of a cross member (27) that connects left and right side members (3l, 3r) to dispose a driving battery (34), a tank storage section (30) is formed on a rear side to dispose a fuel tank (32) and a driving motor (9) is disposed on a rear side of the tank storage section (30). A power cable (26) from a terminal block (34a) of the driving battery (34) is routed and fixed as appropriate so as to bypass the fuel tank (32) via the left side of the fuel tank (32) in the tank storage section (30) and connected to the driving motor (9) via a junction box (21). In an extra length routing area (37) on a side wall (27a) of the cross member (27), an extra length area (26a) is formed by slackening the power cable (26) in a semicircular shape. |
| US12233695B1 |
Electric vehicle having motor shield
An electric vehicle includes a pair of opposed longitudinal outer rails, a plurality of cross beams, a pair of opposed longitudinal inner rails, a housing and a plurality of bushings. The cross beams extend in a transverse direction of the electric vehicle and include first and second cross beams secured to the pair of opposed longitudinal outer rails. The pair of opposed longitudinal inner rails are located inboard of the pair of opposed longitudinal outer rails and between the first and second cross beams. The pair of opposed longitudinal inner rails are secured to the first and second cross beams to form a box. The housing is connected to the box and is configured to be connected to the motor. The bushings are at least partially supported by the housing. |
| US12233691B2 |
Windshield defroster for a vehicle
A vehicle has a windshield, a cladding element having a front surface, which faces the windshield, a rear surface, which faces away from the windshield, and a top surface, which is arranged between the front surface and the rear surface and is angled toward the front surface and rear surface. An airflow element has a wall element, a grille element and an air inlet. At least the front surface and the top surface of the cladding element have a recess in which the wall element and the grille element are arranged. The grille element is designed to direct air from the airflow element to the windshield. |
| US12233687B2 |
Transport climate control remote management
A method of remotely managing a transport climate control system (TCCS) includes a remote management device receiving performance data from the TCCS. The performance data based on one or more detected operating parameters of the climate control circuit. The method also including the remote management device providing the performance data to one or more user devices. A remote management system includes a remote management device configured to receive performance data for a climate control circuit from a climate controller of a TCCS and to provide the performance data to one or more user devices. A TCCS includes a controller configured to: generate performance data based on the one or more detected operating parameters of a climate control circuit, and transmit the performance data to a remote monitoring device. The climate controller also configured to receive an operating instruction from the remote monitoring device. |
| US12233685B2 |
Reheating method for operating a refrigeration system for a motor vehicle, refrigeration system, and motor vehicle having a refrigeration system of this type
A reheating method for operating a refrigeration system for a motor vehicle. The refrigeration system includes a refrigerant compressor, connected to a primary line and a secondary line; an external heat exchanger; an evaporator; a heating register; at least one movable temperature flap; and at least one shutoff element, which is arranged downstream of the heating register in the secondary line. The reheating method includes following steps: setting the at least one shutoff element in a position in which the refrigerant flows into the evaporator downstream of the heating register while bypassing the external heat exchanger, and incorporating at least one further heat sink, which is fluidically arranged in parallel or in series to the evaporator, in particular a chiller operating as a water heat pump evaporator and/or the external heat exchanger operating as an air heat pump evaporator. |
| US12233683B2 |
Optimized power distribution to transport climate control systems amongst one or more electric supply equipment stations
A method for optimizing power distribution amongst one or more electrical supply equipment stations at a power distribution site is provided. The method includes obtaining infrastructure data about the power distribution site, obtaining vehicle/transport climate control system data from one or more transport climate control systems and one or more vehicles demanding power from the one or more electrical supply equipment, and obtaining external data from an external source that can impact power demand from the one or more transport climate control systems. Each of the one or more transport climate control systems configured to provide climate control within a climate controlled space. The method also includes generating an optimized power distribution schedule based on the infrastructure data, the vehicle/transport climate control system data and the external data, and distributing power to the one or more transport climate control systems based on the optimized power distribution schedule. |
| US12233679B2 |
Semi-rigid axle for a vehicle
A semi-rigid axle for a vehicle may include a torsion profile, which extends in a Y direction and is open downward in a Z direction; and two longitudinal control arms, which are connected to the semi-rigid axle and are each connected to the torsion profile by a gusset plate arrangement. Each gusset plate arrangement has a first gusset plate welded to one of the two longitudinal control arms and a second gusset plate arranged at least partially above the first gusset plate. First and second connecting sections of the first and second gusset plates are connected to one another and each of the first and second gusset plates is welded to an inside of the torsion profile on both sides in an X direction. |
| US12233674B2 |
Bracket for mounting a tire pressure sensor
An inflation manifold connected to dual pneumatic tires by air hoses provides a central location for tire inflation and location of pressure sensors. A hose block connected to dual pneumatic tires by air hoses provides a central location for location of pressure sensors. The pressure sensors may be TPMS sensors or a combination of TPMS sensor and pressure gauge. |
| US12233673B2 |
Tyre-removal apparatus with automatically pivoting tool
A tyre-removal apparatus includes a base having a support for receiving and rotating a wheel, and a frame joined to the base having an upright with a longitudinal axis substantially parallel to an axis of rotation of the wheel. A support arm associated with the upright is movable substantially parallel to the axis of rotation of the wheel. A tool for operating on the wheel is mounted pivoting on the support arm. A sensor associated with the tool detects a parameter representing contact between the tool and the wheel, and is connected to a control unit controlling an actuator associated with the support arm, to pivot the tool between a withdrawn position with respect to the axis of rotation of the wheel and an advanced position with respect to the axis of rotation of the wheel, depending on the parameter representing contact between the tool and the wheel. |
| US12233670B2 |
Pneumatic vehicle tyre with circumferential groove
A pneumatic vehicle tire having a tread (2) which has a profiling and which has at least one circumferential groove (1) which runs in encircling fashion in the circumferential direction of the pneumatic vehicle tire and is formed to a profile depth PT and which has, in alternating fashion over the entire tire circumference over partial sections (21, 24) of the circumference of the pneumatic vehicle tire, a first cross section perpendicular to the circumferential direction and a second cross section perpendicular to the circumferential direction. The first cross section is made up of at least two groove portions adjoining one another in a first radial direction R1 of the pneumatic vehicle tire, a first groove portion (3) which is symmetrical to the first radial direction R1 and the width BV,1 of which in the axial direction A of the pneumatic vehicle tire is less than 3 mm and varies by no more than 10%, and a radially inner second groove portion (4) which extends in the axial direction A in relation to the first groove portion (3) and has the largest cross-sectional area of all of the groove portions. The second cross section is made up of at least two groove portions which adjoin one another in a second radial direction R2 of the pneumatic vehicle tire and are symmetrical to the radial direction R2, a first groove portion (33) which widens outward, and an inner second groove portion (34) which is narrowed in relation to the first groove portion and the width BY,2 of which varies in the axial direction A of the pneumatic vehicle tire by no more than 10% and is less than 40% of the width BY,O in the axial direction A of the second cross section on the surface of the tread when the pneumatic vehicle tire is new. The second groove portion (34) of the second cross section extends here in the radial direction R2 over at least 50% of the height H2V of the second groove portion (4) of the first cross section in the radial direction R1, and over at least 50% of its height H2Y in the radial direction R2 is at a distance from the surface of the tread (2), at which the second groove portion (4) is located in the first cross section. |
| US12233669B2 |
Tire for motorcycle for running on rough terrain
A tread portion 2 of a tire 1 includes a plurality of shoulder blocks 11 and a plurality of middle blocks 12. An inner edge 11B in the tire axial direction of a tread surface of each shoulder block 11 protrudes on an outer side in a tire radial direction with respect to a virtual profile 18. A side surface S on the inner side in the tire axial direction of each shoulder block 11 includes one first side surface S1 extending from the inner edge 11B toward a groove bottom, and at least one second side surface S2 extending from a bottom side end of the first side surface S1 toward the groove bottom, and the second side surface S2 is a surface inclined toward the inner side in the tire axial direction relative to the first side surface S1. |
| US12233665B2 |
Chalk box with line lock assembly
A line lock assembly for locking a retraction assembly of a chalk box may include a line lock cover (250) operably coupled to a housing of the chalk box to form a line lock member enclosure, and a line lock member (260) disposed within the line lock member enclosure. The line lock member may be configured to move responsive to rotation of the line lock cover to alternately lock the retraction assembly and unlock the retraction assembly based on a position of the line lock cover. |
| US12233662B2 |
Hot stamping method
A hot stamping apparatus and a hot stamping method are for collectively decorating a plurality of decoration objects using a decorative sheet. In a hot stamping apparatus, an upper chamber and a lower chamber are partitioned by a partition sheet and pressing bodies, so that decorative sheet pieces can be used instead of a decorative sheet having a large area. Then, by using the decorative sheet pieces, local thermal deformation can be prevented. A usage amount of the decorative sheet can be reduced, and three-dimensional decoration can be implemented as needed on a portion requiring decoration. |
| US12233661B2 |
Digital pen with enhanced educational and therapeutic feedback
Disclosed is a digital pen that tracks the user's writing and provides useful feedback based on the user's writing. In one embodiment, the pen may provide feedback when the user has written a misspelled word, invalid mathematical expression, or any noncompliant expression. The pen may also provide feedback relating to the user's handwriting. The feedback may be visual, auditory, or tactile, and may be realtime or delayed. Statistics relating to the user's performance may be tracked, uploaded to external devices, and shared with others. This allows the user and interested parties to track the user's progress over time. The disclosed pen will be useful in educational settings. |
| US12233656B2 |
Method of performing screen printing on a substrate used for the manufacture of a solar cell, controller and apparatus for performing same
A method of performing screen printing on a substrate used for the manufacture of a solar cell is provided. The method includes moving a print head over a screen by a first drive actuator to perform a printing stroke in a first direction. The method includes moving a material processing head in the first direction by a second drive actuator to perform a material processing stroke behind the print head. The print head is moved away from the material processing head by the first drive actuator during a distance increasing phase of the printing stroke to increase a separation distance between the print head and the material processing head. |
| US12233655B2 |
Printer device
A printing device for printing on a label sheet includes a first print head to perform printing on a first side of a label sheet being conveyed along a conveyance path. The label sheet is interposed between the first print head and a first roller. A second print head is upstream of the first print head and performs printing on a second side of the label sheet. A second roller is adjacent the second print head across the conveyance path. A cutter is downstream of the first print head to cut off a first portion of the label sheet. A processor is configured to cause the label sheet to be conveyed in a second direction after the first portion is cut off from the sheet so that the cut end of the sheet reaches the first print head. |
| US12233653B2 |
Liquid ejecting head and liquid ejecting apparatus
A liquid ejecting head includes a liquid ejecting section, a first-valve-unit adjusting a pressure of liquid to be supplied to the liquid ejecting section, and a housing accommodating the liquid ejecting section and the first-valve-unit, in which the first-valve-unit includes a first-flow-path communicating with the liquid ejecting section, a first flexible film that has a first-inner-surface defining a part of the first-flow-path and a first-outer-surface being opposite from the first inner surface, and is configured to displace in a first-direction from the first-outer-surface toward the first-inner-surface and in a second-direction opposite to the first-direction, and a first-valve-body that is moved between an opening position and a closing position, due to displacement of the first flexible film, and the housing has a first-opening-portion facing at least a part of the first-outer-surface. |
| US12233639B2 |
Source wafer, method, and optoelectronic devices
A source wafer for use in a micro-transfer printing process. The source wafer comprising: a wafer substrate; a photonic component, provided in a device coupon, the device coupon being attached to the wafer substrate via a release layer; and one or more etch stop layers, located between the photonic component and the wafer substrate. |
| US12233635B2 |
Fiber-reinforced films
An apparatus includes a first layer including unidirectional first fibers oriented in a first direction and embedded within the first layer, where the first layer has a thickness of less than 25 μm and a second layer bound to the first layer, the second layer including unidirectional second fibers oriented in a second direction and embedded within the second layer, where the first layer has a thickness of less than 25 μm and where the first direction is nonparallel to the second direction. |
| US12233633B2 |
Acquisition distribution layer
Acquisition-distribution-layers (ADL) comprising a hydroentangled composite are provided. The hydroentangled composite includes (a) a first outer layer including a first plurality of synthetic fibers, (b) a second outer layer including a second plurality of synthetic fibers, and (c) at least one core layer including cellulose fibers comprising natural cellulose fibers, synthetic cellulose fibers, or a combination thereof, in which the at least one core layer is located directly or indirectly between the first outer layer and the second outer layer. The first plurality of synthetic fibers, the second plurality of synthetic fibers, and the cellulose fibers are physically entangled together. The hydroentangled composite further comprises a three-dimensional topography defined by a first outermost surface of the hydroentangled composite, in which the three-dimensional topography includes a plurality raised portions and a plurality of recessed portions. |
| US12233629B2 |
Flexible multilayer film
The present disclosure provides a flexible multilayer film. The flexible multilayer film includes at least three layers. One of the layers is a seal layer and one of the layers is a barrier layer. The seal layer is an ionomer. The backing layer is in direct contact with the seal layer. The backing layer is an ethylene/α-olefin multi-block copolymer. |
| US12233624B2 |
Vehicle laminated glazing and device with associated near infrared viewing system
A laminated vehicle glazing with includes a first extraclear glass sheet forming an exterior glazing, a lamination interlayer and a second glass sheet forming an interior glazing with a traversing hole in these last two. |
| US12233620B2 |
Thermoplastic liquid crystal polymer molded body and method for manufacturing same
A thermoplastic liquid crystal polymer (TLCP) molded body including a thermoplastic polymer capable of forming an optically anisotropic melt phase. The TLCP molded body includes an adherend portion in at least a part of the TLCP molded body. The adherend portion has a surface satisfying: a ratio |
| US12233614B2 |
Auto extruded split/spherical tee and full encirclement saddle
The disclosure describes an automated system and method to manufacture extruded split tees, spherical tees, and full encirclement saddle (FES) component parts. The system and method provide for the manufacture of pipe reinforcement components from raw material plates, comprising: an input storage for the raw material plates; one or more ovens for heating the plates; one or more extrusion presses for extruding the heated raw material plates into one or more pipe reinforcement components and an output storage for the pipe reinforcement components. A robotic device is adapted to automatically access and perform operations at the input storage, at the one or more ovens, at the one or more extrusion presses, and at the output storage. |
| US12233612B2 |
Display system
A display system includes an optical system and a curved display disposed to emit light toward the optical system. The optical system includes at least a first optical lens, a partial reflector and a reflective polarizer. The optical system has an optical axis such that a light ray propagating along the optical axis passes through the first optical lens the partial reflector and the reflective polarizer without being substantially refracted. At least one major surface of the optical system can be rotationally asymmetric about the optical axis. A major surface of the optical system may have a first portion defined by a first equation and a second portion adjacent the first portion defined by a different equation. The first optical lens may have a contoured edge adapted to be placed adjacent an eye of a viewer and substantially conform to the viewer's face. |
| US12233611B2 |
Functional wafers by 3D printing
A method of manufacturing an optical lens (417, 901), comprising: obtaining (S301) a transparent thermoplastic (TP) carrier (410, 1210) with at least one smooth surface; printing (S305), via a 3-D printer on the side opposite to the at least one smooth surface of the transparent TP carrier (410, 1210), at least one transparent layer (420, 1220) using a thermoplastic filament (403), each transparent layer (420, 1220) having a predetermined light filtering property, thereby forming a functional layer (420, 1220); and performing (S307) an injection over-molding process (415) to fuse bond the functional layer (420, 1220) to a thermoplastic substrate thereby forming the optical lens, wherein the at least one smooth surface of the transparent TP carrier (410, 1210) forms a smooth surface of the manufactured optical lens (417, 901). |
| US12233608B2 |
Apparatus for automatic manufacturing of wind turbine blades
An apparatus and method for the automatic manufacturing of wind turbine blades, including an elongate tool support (2) with a main suspension beam (4), a plurality of support frames (8) supporting the main suspension beam (4) above the wind turbine blade mould (1), an elongate guide rail (5) provided on the main suspension beam (4) so as to extend longitudinally along the main suspension beam (4), a slider base (6) slidably mounted on the guide rail (5), a drive mechanism (53) for driving the slider base (6) longitudinally along the guide rail (5) and a tool holder (7) mounted on the slider base (6). The apparatus/method improves the efficiency and accuracy of the blade manufacture, and also reduces the exposure of the human body to harmful substances used in blade manufacture. |
| US12233603B2 |
Slicer systems for generating a molecular dynamic graded lattice structure and their application to additive manufacturing
Slicer system for generating molecular dynamic graded lattice structures that can be used as infill for additively manufactured articles. Molecular dynamically generated lattice infill is based on force balancing a node distribution instead of a circle packing. Field data can be utilized to adjust the spacing of the node distribution according to a force balance equilibrium model that accounts for the field expected to be experienced by the article being additively manufactured. The resultant non-uniform honeycomb structures from force-balancing robustly and efficiently address the connection issues with traditional non-uniform lattice structures. |
| US12233592B2 |
Solid-state additive manufacturing methods for compounding conductive polymer compositions
Solid-state additive manufacturing methods for compounding conductive plastic compositions, fabrication of conductive plastic parts and conductive coatings, and plastic recycling are disclosed. Electrically conductive or thermally conductive plastic compositions are compounded and subsequently printed with the solid-state additive manufacturing system. The solid-state fabricated compositions, parts and coatings can also be manufactured to be both thermally and electrically conductive. Solid-state plastic waste recycling methods are also disclosed where various plastic waste materials and shapes are solid-state processed. The plastic waste can be mixed with virgin plastic material or mixed with other types of materials such as metals, ceramics or their combination. The waste plastic feedstock is reinforced with different types of reinforcing particles or fibers, or various additives are added for improving properties of the final deposits. |
| US12233591B2 |
Apparatus for slip and wedge systems
Embodiments presented provide for a method of making as well as an apparatus for holding a hydraulic fracturing plug in a desired position within a wellbore. The hydraulic fracturing plug is configured with a slip and wedge system to maintain the desired position within the wellbore. |
| US12233589B2 |
Integrally blow-moulded bag-in-container having a bag anchoring point, process for the production thereof, and tool thereof
The invention is an integrally blow-moulded bag-in-container obtainable by blow-moulding an injection moulded multi-layer preform. The bag-in-container includes an inner layer forming the bag and an outer layer forming the container, and a single opening, the mouth, fluidly connecting the volume defined by the bag to the atmosphere. The container further includes at least one interface vent fluidly connecting the interface between inner and outer layers to the atmosphere, wherein the bag is anchored to the outer layer at at least one point remote from the single opening and interface vent. The invention also relates to a process and a mould for the production of the blow-moulded bag-in-container. |
| US12233587B2 |
Coextrusion die for manufacturing multilayer tubular preforms made from thermoplastic plastic
A coextrusion die for manufacturing multilayer, coextruded, tubular preforms made from thermoplastic plastic. A storage cylinder element has an inner storage space. A spindle, and an annular storage space is formed between the spindle and the storage cylinder element, which opens into an output ring channel. An extrusion head, which is axially displaceable with respect to the storage cylinder element includes a ring piston, in which at least two heart distributor elements are coaxially arranged. A flow channel is formed in each case between the ring piston and the adjacent heart distributor element as well as between each of two heart distributor elements, which widens from an inlet opening to a distributor ring channel from where it transitions into a cylindrical ring channel as a frustoconical ring channel. |
| US12233586B2 |
Machine and method for forming articles
A machine and method of forming an article generally comprising extruding a molten bead of thermoplastic material along x, y and z axes in forming an article consisting of a strata of such material, and passing a roller over each applied portion of such molten bead to compress such bead portion, enhancing the fusion of engaging plies of such extruded material. |
| US12233585B2 |
Method and apparatus for producing a dispensing part of a container, and dispensing part of a container
A method comprises in sequence the steps of: dispensing a continuous polymeric extrudate in a molten state; separating from the continuous extrudate a dose substantially having the shape of a parallelepiped, the dose having a separation surface at which the dose has been separated from the continuous extrudate, the dose further having a face adjacent to the separation surface; conveying the dose towards a mould comprising a first mould part and a second mould part; shaping the dose in the mould by moving the first mould part and the second mould part one towards the other in a moulding direction arranged transversally to said face, thereby obtaining a dispensing part of a container. The dispensing part comprises: an edge zone suitable for being joined to a container body; a neck surrounding a passage through which a product contained in the container can be dispensed; a membrane which closes the passage, the passage being intended to be opened after the shaping step, so that said product can flow out. |
| US12233579B2 |
Foaming and shaping process for a thermoplastic sheet, and associated apparatus and shaped foamed thermoplastic sheet
A method of foaming and shaping a thermoplastic sheet comprising a poly(phenylene ether), a polyetherimide, or a combination thereof includes foaming the thermoplastic sheet with supercritical carbon dioxide to form a foamed thermoplastic sheet, and shaping the foamed thermoplastic sheet to form a shaped foamed thermoplastic sheet. The shaping step includes compressing the foamed thermoplastic sheet between a first metal plate and a secondi metal plate, each of which has a grooved surface facing the thermoplastic sheet. The first metal plate and the second metal plate are connected by a flexible, compressible linkage capable. When the flexible, compressible linkage is in its uncompressed state, only the second (lower) metal plate is in contact with the shaped foamed thermoplastic sheet. When the flexible, compressible linkage is in its compressed state, both the first (upper) and second (lower) metal plates are in contact with the shaped foamed thermoplastic sheet. |
| US12233578B2 |
Devices and methods for dynamic pixel molding
Systems and methods for reusable molding devices in accordance with embodiments of the invention are disclosed. In one embodiment, a reusable molding device is provided comprising: an array comprising a plurality of pixel pins, which are arranged to form a two-dimensional plane and which are each linearly movable to create an impression of a surface of an object, a first pixel guide plate, a second pixel guide plate, a first clamp pressure plate, a second clamp pressure plate, a first clamp screw, wherein the first clamp screw moves the first clamp pressure plate towards the first side of the array, a second clamp screw which moves the second clamp pressure plate towards the second side of the array, a pressure clamp frame enclosing the first and second pixel guide plates and the first and second clamp pressure plates, and a top pressure plate, which includes an injection entrance bore. |
| US12233572B2 |
Methods to eliminate mudcracks in CMC matrix by humidity controlled atmosphere
Methods of reducing dry crack formation in ceramic matrix composite green bodies are provided. Some of the methods expose the green body to a gaseous atmosphere at a relatively high humidity for a first period, and then slowly lower the humidity over a second period, where the gaseous atmosphere is at room temperature for both periods. Other methods start the gaseous atmosphere at room temperature and then raise the temperature to a higher temperature while the humidity is relatively high, and hold that temperature even as the humidity is lowered in the second period. |
| US12233571B2 |
Construction method for spatial aggregate reinforced 3D printed concrete structure
A construction method for a spatial aggregate reinforced 3D printed concrete structure, includes: selecting a structural member, performing mechanical analysis, and determining a basic dosage and a printing and weaving process of an implanted reinforcement, determining a type, positioning and dosage of a spatial aggregate, preparing 3D printing materials, editing an electromagnetic signal and positioning push program according to the selected positioning and dosage of the spatial rigid aggregate, the 3D printing material is extruded along the printing and weaving process and the spatial rigid aggregate is evenly scattered, and realizing the connection between spatial aggregates and the connection between the spatial aggregates and the reinforcements, a spatial aggregate reinforced 3D printed concrete structure is formed after layer-by-layer construction, superimposed and hardened, or after segmented printing, component nodes are connected through lap design of preset tenon and mortise and reinforcement. |
| US12233569B1 |
Coping nailer
A wheeled conveyance straddles and squeezes a parapet or similar vertical wall from both the inside and outside vertical faces. Side wheels may be adjusted to be closer together or farther apart to accommodate the thickness of the wall being straddled. The conveyance traverses the parapet along the top edge, and at least one fastener driver suspended from the carriage faces one or both of the inside and outside vertical faces at some preferably adjustable distance below the top edge of the parapet. While the conveyance traverses the parapet, an actuator selectively and repeatedly actuates the fastener driver(s). Various sensors and controls are provided that permit the speed, fastener spacing, and travel distance to be adjusted. Position awareness and visual, auditory, and radio communications may optionally be employed. |
| US12233568B2 |
Wood optimization system, method of optimizing wood products and wood product selector therefore
There is described a wood optimization system for a production line. The wood optimization system generally having a conveyor moving wood products across a handling area; a wood product selector positioned proximate to a selected wood product in the handling area; and a computer vision system along the production line having a camera imaging the handling area, a processor communicatively coupled to the camera, and a computer-readable memory having program code that when executed by the processor perform the steps of: receiving from the camera an image representing at least a portion of the handling area; finding the wood product selector in the image; identifying the selected wood product in the image as the wood product of the plurality being most proximate to the wood product selector; receiving an instruction associated to the selected wood product; and implementing the instruction into optimization data associated to the selected wood product. |
| US12233562B2 |
Folding knife
This disclosure describes systems, methods, and apparatus for a locking folding knife having a handle lock and a safety switch arranged around and rotatable around a pivot axis of the knife. In an engaged position the switch overlaps at least a portion of the handle lock and prevents it from moving into an unlocked position. A spring, such as a wire form spring, can be arranged within a pocket of the switch, and when the switch is moved between engaged and disengaged positions the spring can be compressed generating a rotational bias on the switch urging the switch toward either the engaged or disengaged position. |
| US12233559B2 |
Systems and methods for automated framing construction
Techniques of automated framing for use in the construction of building structures are described. Examples of such structures includes walls, wall panels, roofs, and the like. In one scenario, a robotic automated framing system assists with construction of a building structure. The robotic automated framing system can analyze an architectural plan and determine a project, based at least in part, on the architectural plan. The robotic automated framing system can also schedule a robot to perform the project, and cause the robot to perform at least some of the project. |
| US12233558B2 |
Robotic control for tool sharpening
This disclosure describes systems, methods, and devices related to robotic control for tool sharpening. The device may determine a first location associated with a first cutting tool of the one or more cutting tools relative to the first container. The device may grip the first cutting tool based on the first location of the first cutting tool relative to the first container. The device may move the robotic device to one more scanning sensors. The device may collect three dimensional data. The device may extract a profile of the first cutting tool. The device may determine a top edge and a bottom edge based on the profile. The device may determine a tip of the first cutting tool. The device may generate a sharpening path based on the tip and the profile of the first cutting tool. |
| US12233555B2 |
Cleaning robot and task performing method therefor
A task performing method for a cleaning robot, according to the disclosure, comprises the operations of: photographing an object in proximity to the cleaning robot includes obtaining recognition information of the object included in the photographed image, by applying the photographed image to a trained artificial intelligence model, obtaining, from among a plurality of sensors, additional information of the object by using a result obtained by detecting the object by at least one sensor selected, based on the recognition information of the object, and performing a task of the cleaning robot based on the additional information of the object. The trained artificial intelligence model, for example, a deep learning neural network model, in which a plurality of network nodes having weights are located in different layers so as to exchange data according to a convolution relationship, can be used, but is not limited to the aforementioned example. |
| US12233548B2 |
Robotic system with enhanced scanning mechanism
A method for operating a robotic system including determining an initial pose of a target object based on imaging data; calculating a confidence measure associated with an accuracy of the initial pose; and determining that the confidence measure fails to satisfy a sufficiency condition; and deriving a motion plan accordingly for scanning an object identifier while transferring the target object from a start location to a task location. |
| US12233547B2 |
Powering a surgical robot arm
A control system for a surgical robotic system, the surgical robotic system comprising a remote surgeon console having a surgeon input device, and a surgical robot arm comprising a series of joints extending from a base to a terminal end for attaching to a surgical instrument, the surgical robot arm operable in a full power mode in which the joints of the surgical robot arm are powered by a first power source and a reduced power mode in which the joints of the surgical robot arm are powered by a second power source, the control system configured to: whilst the surgical robot arm is operating in the full power mode, control the surgical robot arm in a surgical mode by converting movements of the surgeon input device to control signals for moving joints of the surgical robot arm; detect a power failure of the first power source; in response to detecting the power failure, enable the reduced power mode, and transition control of the surgical robot arm from the surgical mode to a standby mode; whilst in the reduced power mode, receive a command from a user input located on or adjacent to the surgical robot arm or on the surgeon console; and in response to receiving the command, transition control of the surgical robot arm from the standby mode to a calibration mode. |
| US12233546B2 |
Robot
A robot includes: a chest; a pair of right and left upper limbs; and a pair of right and left shoulders connecting the right and left upper arms rotatably to the chest with two rotational degrees of freedom, respectively. The shoulder includes: a shoulder joint connecting the upper arm rotatably; a chest-side main link attaching unit provided; an upper arm main link attaching unit provided in the upper arm; an upper arm drive main actuator including an upper arm drive main link having a variable length and a power source for generating force changing the length of the upper arm drive main link; a chest-side auxiliary link attaching unit provided in the chest; an upper-arm-drive-main-link-side auxiliary link attaching unit provided in the upper arm drive main link; and an upper arm drive auxiliary actuator including an upper arm drive auxiliary link having a variable length and a power source for generating force changing the length of the upper arm drive auxiliary link. |
| US12233543B2 |
Wire routing for robotic manipulator
A robot includes an input link, an output link, and a wire routing. The output link is coupled to the input link at an inline twist joint where the output link is configured to rotate about the longitudinal axis of the output link relative to the input link. The wire routing traverses the inline twist joint to couple the input link and the output link. The wire routing includes an input link section, an output link section, and an omega section. A first position of the wire routing coaxially aligns at a start of the omega section on the input link with a second position of the wire routing at an end of the omega section on an output link. |
| US12233539B2 |
Systems and methods for plant embryo orientation and replating
Methods and systems are provided for singulating, orienting, and delivering oriented objects (e.g., embryos) to a desired location (e.g., a plate containing a selected medium). |
| US12233536B2 |
Digital finger
A digital finger for testing a touchscreen of an appliance using a testing robot is provided. A control circuit receives, from a load cell, first signals indicative of pressure applied by a finger holder simulating interaction with the touchscreen, the load cell being held by a load cell housing defining a channel for receiving the finger holder, such that when the finger holder is pressed onto the touchscreen, the finger holder moves to increase pressure against the load cell. The control circuit receives, from the appliance, second signals indicative of recognition of a touch to the touchscreen. The control circuit determines, response time of the touchscreen and/or the pressure required to operate the touchscreen based on the first and second signals. |
| US12233534B2 |
Robot
Provided is a robot capable of automatically confirming the accuracy of a three-dimensional sensor and correcting the accuracy. The robot comprises: a three-dimensional sensor; a notification unit for notifying a determination timing for determining a deviation of an optical system of the three-dimensional sensor, on the basis of a change in a physical quantity related to the three-dimensional sensor; and a determination unit for determining whether or not there is a deviation at the optical system of the three-dimensional sensor. The change in the physical quantity includes at least one of acceleration and the number of times of acceleration and deceleration added to the three-dimensional sensor, a change in temperature of the three-dimensional sensor within a certain period, a change in temperature of the three-dimensional sensor within a total operating period, and the number of times of change in temperature of the three-dimensional sensor within the total operating period. |
| US12233532B2 |
Robot, and outer skin thereof
The present invention provides a structure that is effective in providing a robot with appropriate warmth. A robot includes a frame, a surface skin that covers the frame, a heat source that heats a fluid, and a pressurizing unit that pressurizes a space enclosed by the frame. A heated fluid flows out from the space owing to the space being pressurized. A fluid layer is formed on an inner side of the surface skin covering the frame by the fluid that has flowed out from the space. |
| US12233529B2 |
Interchangeable and interconnectable tool organizing device
A custom tool accessory to hold a tool, the custom tool accessory including a body, at least one tongue disposed at a first side of the body, at least one tongue receiving groove disposed at a second side of the body opposite from the first side of the body, and a tool holding portion disposed on the body to hold the tool. At least one magnet is attached to the underside of a metallic base plate that is in turn secured to the underside of the body. A retainer surrounds the at least one magnet and also underlies the area of the bottom of the base plate that is not covered by the at least one magnet. |
| US12233518B2 |
Method for the servo-installation of a threaded fastener
A method for the installation of a threaded fastener (10) in a structure, the threaded fastener comprising a screw (20) and a nut (28), the method comprising the following steps: a) inserting the screw into the structure, and tightening the nut onto the screw, b) simultaneously transmitting/receiving ultrasonic waves into/from the fastener for the measurement of a parameter representative of a variation in said waves, said first parameter providing an indirect measurement of an axial tension in the screw, c) stopping the screwing when a target value for the first parameter is reached. The process further comprises determining the thickness of the structure to be tightened, and determining the target value of the first parameter in accordance with the thickness of the structure to be tightened and the geometrical characteristics of the fastener (10). |
| US12233515B2 |
Torque sensing arrangement of power tool
A power tool includes a housing (10), a power device (20), a bearing set (30), a torque post (40) and a torque sensor (50). The housing (10) includes a main body (11) and a handle (12) perpendicularly connected to one side of the main body (11). The power device (20) is disposed in the main body (11) and includes a power body (21) and a bushing (22) adapted to sheathe the power body (21). The bearing set (30) is arranged between the bushing (22) and the housing (10). The power body (21) may rotate relative to the housing (10). The torque post (40) is disposed in the handle (12) and abuts against the bushing (22). The torque post (40) is arranged perpendicularly to the power body (21). The torque sensor (50) is disposed on the torque post (40). |
| US12233511B2 |
Coated abrasives having an improved supersize coating
Systems and methods include providing a coated abrasive article with an enhanced anti-loading composition in a supersize coat. The anti-loading composition includes a mixture of a metal stearate, at least one performance component, and a polymeric binder composition. |
| US12233509B2 |
Cutting elements and methods for fabricating diamond compacts and cutting elements with functionalized nanoparticles
A method of fabricating a diamond compact includes functionalizing surfaces of diamond nanoparticles with fluorine; combining the functionalized diamond nanoparticles with a non-group-VIII metal to form a particle mixture; and subjecting the particle mixture to high pressure and high temperature (HPHT) conditions to form inter-granular bonds between the diamond nanoparticles. A cutting element for an earth-boring tool includes a plurality of grains of diamond material; a plurality of diamond nanoparticles bonded to the plurality of grains of diamond material; and a non-group-VIII metal fluoride disposed within interstitial spaces between the grains of diamond material and the plurality of diamond nanoparticles. The cutting element is substantially free of a metal-solvent catalyst. |
| US12233507B2 |
Apparatus for changing an abrasive sheet in an abrading machine
A system for replacing an abrasive sheet in a sanding machine including a working head in which it is provided a support body having an engagement surface arranged to engage with an abrasive sheet. The sanding machine also includes a handling device arranged to actuate the support body in space according to at least two degrees of freedom. The system may include a computing device to compute the spatial orientation of the support body. Furthermore, the system may include a removal station having a gripping element configured to grip the abrasive sheet in order to disengage the abrasive sheet from the support body. |
| US12233506B2 |
Centerless roll grinding machine with reduced radial variation errors
A centerless roll grinding machine includes a lateral support of a V-channel support that is received by a vertical support of a frame and extending horizontally in the first direction to contact a second side of one neck of a work roll. A lower support received by and extending generally upwardly from the frame displaced in the first lateral direction from a geometric center of the neck of the work roll cooperates with the lateral support to provide the V-channel support to hold the work roll for rotation about a longitudinal axis. A lateral support device includes radially spaced bearing pads on the neck in opposition to a grinding wheel. Each pair of bearing pads is pivotally attached to a respective first tier averaging link that is pivotally coupled to a horizontal ram to reduce displacements of the work roll caused by errors in the neck. |
| US12233499B2 |
Damper
A milling machine includes a spindle which is arranged to receive a tool holder and in use to cause rotation of the tool holder within the spindle. A portion of the spindle housing surrounding the tool holder is provided with at least one pair of opposing damping units. |
| US12233497B2 |
Joining tool and tool gripper
A joining tool unit including a hold-down device with a movable tool and a tool counter element. The hold-down device together with the movable tool and the tool counter element are provided opposite each other. A workpiece can be positioned between the hold-down device and the tool counter element in the arranged state. The movable tool and the tool counter element interact in order to form a joint connection. A light-guiding system is formed on the hold-down device, to conduct a light beam in the direction of a joint location of the workpiece when the workpiece is arranged on the joining tool unit. A flow channel for a fluid is defined along a section of the light beam up to a workpiece-side end of the hold-down device. |
| US12233496B2 |
Mobile fastener machine platform
An apparatus for providing an efficient platform for installing screws can include a cart with wheels and a screw assembly mounted to the cart. The screw assembly can include a screwing device that rotates a drive shaft that engages a screw, a screw guide tube and a screw feeding tube connected to the screw guide tube. In another embodiment, an assembly is provided. The assembly may include a bracket for coupling to a moveable platform, a screwing device coupled to the bracket and that rotates a drive shaft that engages a screw, a screw guide tube and a screw feed tube connected to the screw guide tube. |
| US12233495B2 |
Precision assembly process and advance tooling methods of use
Aspects of the present disclosure relate generally to the manufacture of assemblies of components, and in particular to methods, apparatus, and systems for performing manufacturing operations. In one aspect, a method of manufacturing an assembly of components includes positioning first and second components into a nominal configuration with respect to each other at a first factory location. The method further includes drilling a fastener joining hole through an interface of the first and second components at the first factory location. The method further includes positioning the first and second components for fastener joining at a second factory location. The method further includes inserting a fastener into the fastener joining hole to couple the first and second components together. |
| US12233493B2 |
Heat transfer sheet, method for producing heat transfer sheet, heat transfer sheet package, and method for producing heat transfer sheet package
A method for producing a heat transfer sheet, includes: (A1) forming a mixture including at least one of a carbon fiber and a boron nitride flake, an inorganic filler, and a binder resin into a molded body in which the at least one of the carbon fiber and the boron nitride flake is oriented in a thickness direction of the molded body; (B1) slicing the molded body into a sheet shape to obtain a molded sheet; (C1) pressing the molded sheet; and (D1), after the pressing, inserting the molded sheet between films and performing a vacuum packing of the molded sheet with the films such that an uncured component of the binder resin present inside the molded sheet is exuded to a surface of the molded sheet, which is the heat transfer sheet. |
| US12233492B2 |
Inert gas welding torch head with adjustable electrode receiver
A removable arc welding torch head having a variable electrode receiving aperture that includes a number of discrete, slidable wedges guided within a conical interior surface to enable the head to be used with electrodes of various diameters without changing components of the torch head. The removable nature of the torch, while providing for adequate flow of inert gas, provides an adjusting collar that engages the wedges and forms an adjustable opening for an electrode to be inserted therein. |
| US12233491B2 |
Welding method for connecting a first connector to a second connector, the use of the welding method, and a welded connection
A welding method includes providing a first connector having a first end, providing a second connector having a second end for being welded to the first end, overlapping the first end and the second end, applying a contactless heating to a central section of the first end and melting an end section of the first end facing the second connector, and cooling the first end and the second end to form a weld connecting the first connector and the second connector. The first connector and the second connector extend in opposite directions from the weld. |
| US12233490B2 |
Welding power supply
A welding power supply includes a DC power supply circuit that outputs DC power, an inverter circuit provided with a plurality of switching elements and configured to receive the DC power from the DC power supply circuit and to output AC power, a current sensor that detects output current from the inverter circuit, and a controlling circuit that controls the DC power supply circuit and the inverter circuit. In switching the output polarity of the inverter circuit, the controlling circuit reduces the output of the DC power supply circuit, then provides a short-circuit state by setting all of the switching elements to ON, and then switches a switching element that was ON before the short-circuit state to OFF when the absolute value of an instantaneous value of the output current decreases to or below a threshold value. |
| US12233489B2 |
Methods and apparatus to communicate via a welding arc
Methods and apparatus to communicate via a welding arc are disclosed. An example welding-type power supply includes a power converter, a weld monitor, and an arc modulator. The power converter outputs welding power to sustain a welding-type arc at a welding-type torch. The weld monitor monitors one or more aspects of a weld performed using the welding-type arc and the welding-type torch, and selects an audio message based on the one or more aspects. The arc modulator configured to modify the welding-type arc to output the selected audio message as a plasma speaker. |
| US12233488B2 |
Systems and methods for tracking weld training arc parameters
A welding system includes one or more sensors configured to detect data relating to one or more arc parameters for the welding system during a weld performed by the welding system. The welding system also includes control circuitry configured to receive the data corresponding to the one or more arc parameters from the one or more sensors, time synchronize the data corresponding to the one or more arc parameters with data relating to one or more welding parameters over a time period for the weld, present the data corresponding to the one or more arc parameters graphically over the time period via a user-viewable screen during the weld, and present the data corresponding to the one or more welding parameters graphically over the time period via the user-viewable screen during the weld. |
| US12233487B2 |
Automatic weld arc monitoring system
An example welding system includes a power supply configured to output welding power; a weld parameter feedback sensor configured to produce a weld feedback parameter corresponding to an actual weld condition during welding; and a welding program comprising: a first weld having first weld parameters; a second weld having second weld parameters, wherein the second weld follows the first weld; a controller configured to, in response to selection of the weld program for performing a welding job on a part: control the power supply to provide the welding power to a first weld operation based the first weld parameters; monitor first feedback from the power supply; control the power supply to provide the welding power to a second weld operation based the second weld parameters; monitor second feedback from the power supply; and determine whether at least one of the welding job or the part is acceptable. |
| US12233486B2 |
Assembly and joining table, systems and methods for automated operations of the same
An assembly and joining table, such as with weld splatter protection features, are disclosed along with systems and methods for operating the same in at least partially automated fashion. The table includes holders positioned about platform providing a work surface. Parts are placed within at least certain of the holders for joining to create an assembly. The holders include conductive surfaces and may include a sinuous recessed channels for wiring connecting the conductive surfaces to an electrical ground. A controller may operate motors of the table and command operations of robots for material handling and/or joining, such as based on data from a machine vision system viewing the table. |
| US12233482B2 |
Intelligent electromagnetic induction heating leveling system and method thereof
An intelligent electromagnetic induction heating leveling system, comprising: a trolley type leveler, an unmanned aerial vehicle temperature measurement device, indoor positioning devices used for converting position information of a trolley of the trolley type leveler and the unmanned aerial vehicle temperature measurement device into position parameters, and a control system. The system can perform, according to preset data parameters, data transmission by means of a wireless local area network and the unmanned aerial vehicle temperature measurement device and control the unmanned aerial vehicle temperature measurement device to move to a specified position. The system intelligently controls the leveling temperature and leveling time of a leveling area, and thus may be suitable for leveling of weld joints having different sizes and depths, and achieve a good leveling effect. Also provided is an intelligent electromagnetic induction heating leveling method. |
| US12233481B2 |
Laser processing device, and method for manufacturing chip
This laser processing apparatus is for forming modified regions in an object, which includes a sapphire substrate having a C-plane as a main surface, along cutting lines by focusing laser light on the object, and is provided with a laser light source, a spatial light modulator, and a focusing optical system. The spatial light modulator performs aberration correction by a first aberration correction amount smaller than an ideal aberration correction amount when the modified region is formed along a first cutting line along an a-axis direction of the sapphire substrate, and performs aberration correction by a second aberration correction amount smaller than the ideal aberration correction amount and different from the first aberration correction amount when the modified region is formed along a second cutting line along an m-axis direction of the sapphire substrate. |
| US12233480B2 |
Information processing device, laser processing machine, judgment method, and recording medium
An information processing device includes a support extraction unit that extracts a support supporting an object corresponding to a cutout region at an outermost position among one or more supports supporting the object based on cutout region information indicating the cutout region as a region to be cut out by a laser processing machine and support information indicating the one or more supports supporting the object corresponding to the cutout region and a judgment unit that judges whether the object will incline and rise by being supported by the one or more supports or not based on a support count as the number of supports supporting the object at outermost positions. |
| US12233479B2 |
Methods of enhancing surface hardness of quench-sensitive age-hardening materials, alloys produced therefrom, and laser cladding systems therefor
Methods of enhancing surface hardness of a quench-sensitive age-hardening material, such as an aluminum alloy, with cryogenic quenching, aluminum alloys produced by the methods, and a laser cladding system with cryogenic quenching capability. Laser cladding or other heat treatment of a quench-sensitive age-hardening material, such as an aluminum alloy, is combined with in-situ cryogenic quenching of the heated area with a spray of cryogenic fluid as the material cools down from the cladding or other heat treatment. The laser cladding system has both a laser emitter to heat a workpiece and a cryogenic nozzle to deliver a cryogenic fluid spray onto the workpiece. The resulting material may have a surface hardness higher than can be achieved without the quenching spray, often approaching or exceeding a T6 temper, without using a solution heat treatment. |
| US12233478B2 |
Laser-assisted additive manufacturing
Laser additive manufacturing apparatus, systems, and methods for the fabrication of high quality freeform high value structures. The apparatus, systems, and methods utilize a material powder having varying particle size and shape as raw material. It can also be adopted to use a wire as the feed material. |
| US12233477B2 |
Hermetic assembly and device including same
Various embodiments of a hermetic assembly and a method of forming such assembly are disclosed. The hermetic assembly includes a dielectric substrate having a first major surface and a second major surface, a patterned layer connected to the first major surface of the dielectric substrate by a laser bond, and a ferrule having a body and a flange extending from the body. The flange is welded to a welding portion of the patterned layer that is disposed between the flange and the first major surface of the dielectric substrate such that the ferrule is hermetically sealed to the dielectric substrate. |
| US12233474B2 |
Methods for laser processing transparent workpieces using modified pulse burst profiles
A method of laser processing a transparent workpiece includes directing a pulsed laser beam into the transparent workpiece. The pulsed laser beam includes pulse bursts having 2 sub-pulses per pulse burst or more, each pulse burst of the pulsed laser beam has a burst duration Tbd of 380 ns or greater; and the pulsed laser beam forms a pulsed laser beam focal line in the transparent workpiece, the pulsed laser beam focal line inducing absorption in the transparent workpiece, the induced absorption producing a defect in the transparent workpiece. The pulsed laser beam focal line includes a wavelength λ, a spot size wo, and a Rayleigh range ZR that is greater than F D π w o 2 λ , where FD is a dimensionless divergence factor comprising a value of 10 or greater. |
| US12233471B2 |
Techniques for forming composite sandwich structures
In some examples, a technique including positioning supports such that the supports are between a first metallic substrate and a second metallic substrate, wherein an undulating member is located between the first metallic substrate and the second metallic substrate, the undulating member defining a plurality of first peaks adjacent to a first surface of the first metallic substrate and a plurality of second peaks adjacent to a second surface of the second metallic substrate, wherein a first support of the supports is positioned such that the first support extends between a first peak of the plurality of first peaks and the second surface of the second metallic substrate; welding the first peak to the first surface of the first metallic substrate in an area of the first support; and removing the first support by at least one of a thermal removal process or a chemical removal process. |
| US12233467B2 |
Hole saw
A hole saw includes a cylindrical body having a sidewall with a first end and a second end opposite the first end. The cylindrical body includes a gullet formed in the sidewall between a leading surface, a trailing surface, and a bottom surface of the sidewall. The gullet defines a central longitudinal axis extending between the first and second ends of the sidewall that is obliquely oriented relative to a rotational axis of the hole saw such that the gullet is angled from the first end to the bottom surface in a direction toward a cutting direction of the hole saw. The gullet has a dimension measured parallel to the rotational axis between the first end of the sidewall and the bottom surface of the gullet that is greater than 1.5 inches. The hole saw includes a cutting tooth coupled to the first end of the sidewall adjacent the gullet. |
| US12233463B2 |
Composition for pressure bonding, and bonded structure of conductive bodies and production method therefor
A composition for pressure bonding contains a metal powder and a solid reducing agent and has a compressibility of 10% to 90%, the compressibility being expressed by a relationship formula using the thickness A of a dried coating film formed by drying the composition in an air atmosphere at 110° C. under atmospheric pressure for 20 minutes and the thickness B of a sintered body formed by treating the dried coating film in a nitrogen atmosphere at 280° C. under a pressure of 6 MPa for 20 minutes. The solid reducing agent may be BIS-TRIS. Also provided is a bonded structure of conductors in which a bonding portion via which two conductors are bonded together is formed by treating, under pressure, the two conductors and a coating film formed of the composition for pressure bonding provided therebetween. |
| US12233459B1 |
Binder trap system
A binder trap system that has more than one binder trap. All of the binder traps are independently connected to a chill unit. The chill unit provides chilled fluid at a precise temperature to chill contents of the binder traps. All of the binder traps are independently connected to a heat unit. The heat unit provides heated fluid at a precise temperature to heat contents of the binder traps. The binder trap system has the capability to independently be chilled or heated from all of the other binder traps in the system. |
| US12233454B1 |
Casting-rolling side sealing device with electromagnetic stirring function
A casting-rolling side sealing device with an electromagnetic stirring function is provided and includes a pair of side sealing plates covering two side ends of a casting-rolling zone from a casting-rolling starting end to a casting-rolling ending end respectively, a pre-tightening force is formed between one of the side sealing plates and adjacent casting rolls. A pulse end of a first electromagnetic assembly releases first pulses along a first axis direction parallel to a direction from the side ends to a center of the casting-rolling zone. The first pulses are configured to generate an electromagnetic stirring effect in the casting-rolling zone. A second electromagnetic assembly is arranged on each of the side sealing plates, a pulse end of the second electromagnetic assembly releases second pulses along a second axis direction perpendicular to the first axis direction. |
| US12233453B2 |
Hand riveter
The present invention discloses a hand riveter and relates to the field of hand-operated tools, and the hand riveter comprises a first handle, a second handle and a clamping and pulling mechanism, wherein the second handle is capable of rotating around a pivoting shaft with respect to the first handle; the second handle is separated into a force applying end and a warping end by the pivoting shaft, and the warping end and the clamping and pulling mechanism are connected via a connecting shaft; when the force applying end of the second handle is rotated and opened with respect to the first handle, the warping end of the second handle drives the clamping and pulling mechanism to move in a rivet-driving direction; and when the force applying end of the second handle is rotated and closed with respect to the first handle, the warping end of the second handle drives the clamping and pulling mechanism to move in a rivet-pulling direction. According to rational arrangements of the present invention, the hand riveter is labor-saving and is comfortable to hold during pull riveting. |
| US12233451B2 |
Rotary cable arranging tool
A rotary cable arranging tool is disclosed. The rotary cable arranging tool is used for untwisting a first and a second cable. The rotary cable arranging tool includes a first annular structure, a first and a second assembly member, and a first and a second hole. The first and the second holes are assembled by the cooperation of the first and the second assemblies so as to be pressed to change a width of an inner diameter. When the first and second cables are in a twisted state, the first and second assemblies are counter-rotated together, so that the first and the second cables are untwisted and enter the first and second holes respectively. Then the first and second holes are tightly combined with the first and second cables, and the first and the second cable are pulled out to be straightened. |
| US12233447B2 |
Hybrid fixture assemblies with additive manufactured features integrated with machined metal features
Presented are hybrid fixture assemblies with integrated additive manufactured features, methods for making/using such fixtures, and manufacturing systems equipped with such fixtures. A manufacturing fixture assembly includes a fixture support frame formed, at least in part, from a first material, and a fixture support shell formed, at least in part, from a second material distinct from the first material. The support frame, which seats on/mounts to a work surface, includes a skeletal substructure with multiple male connectors projecting therefrom. The skeletal substructure contains multiple first frame walls that are removably intermeshed with multiple second frame walls in a collapsible format. The support shell includes a support surface that holds a workpiece, an interface surface that abuts the skeletal substructure, and multiple female connectors that project from the interface surface. Each female connector removably receives therein a respective male connector to thereby detachably mount the support shell to the support frame. |
| US12233437B2 |
Machine, in particular padding machine, to backfill pipelines
Machine, especially a padding machine, for the burying of pipes, in particular arranged in a respective excavation of the ground, gas pipelines, oil pipelines, aqueducts, etc., in particular for covering of said pipe with a corresponding material, in particular a treated material, preferably screened, comprising including a main support framework of the apparatus, in particular which extends according to a respective longitudinal axis of the same machine, a cabin for housing the driver of the machine, such a cabin is in the form of a cabin movable with respect to said main support frame. Said cabin for housing the driver of the machine can be positioned, in corresponding vertical positions, or placed at height levels different from each other, preferably moving vertically, or perpendicularly to said ground. |
| US12233433B2 |
Uniform thin film deposition for poly-p-xylylene
Embodiments of the invention are directed to a deposition chamber for forming a poly-para-xylylene film. A non-limiting example of the deposition chamber includes a chamber body, an inlet coupling the chamber body to a furnace, and an outlet coupling the chamber body to a vacuum pump. The deposition chamber includes at least one heating element arranged on a surface of the chamber body. The heating element is configured to raise an internal temperature of the deposition chamber body to a substantially uniform internal temperature across an entire internal volume of the chamber body. |
| US12233427B2 |
Reject chamber of a centrifugal cleaner and a centrifugal cleaner
A centrifugal cleaner with a reject chamber (1) having a center dilution arrangement (3) with a dilution nozzle (4) to deliver dilution fluid to the reject chamber (1), and a reject outlet (7) at the bottom of the reject chamber (1). The dilution nozzle (4) points outwards to create a crossing outward flow of dilution fluid across an annular space (5) around the dilution arrangement (3) to slow circulating fluid flowing down from a cone (2) of the centrifugal cleaner to the reject chamber (1). The dilution arrangement (3) may have a clearing nozzle (6), directed against the reject outlet (7). The dilution nozzle (4) may be pointed below the bottom end (9) of the cone (2) and the dilution arrangement (3) may not extend higher than the bottom end of the cone. |
| US12233422B2 |
PCR tube, apparatus for PCR including the same and PCR method using the same
Provided is a PCR tube including: an outer tube configured to provide a first space having a blocked lower portion; and an inner tube inserted to the first space. Here, the inner tube includes: an inner tube body configured to provide a second space; and a spiral structure protruding from a side surface of the inner tube body to the outside of the inner tube body, and a micro-channel is defined by the outer tube, the inner tube body, and the spiral structure in a state in which the inner tube is inserted into the first space. |
| US12233420B2 |
Colorimetric sensors and methods of manufacturing the same
A colorimetric sensor for detecting an analyte of interest that includes multiple surfaces and a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. Each surface defines a void (e.g., a pore or a nanohole) and at least one surface defines a fluid inlet. The sensor is configured such that, when an analyte contacts the molecularly imprinted polymer and becomes disposed within the cavity, a wettability of at least one of the surfaces changes thereby to cause a detectable color change in the sensor. Optionally, the sensor may also include a metal layer at a bottom of each void or nanohole and outside a top of each void or nanohole for use as a plasmon resonance-type sensor. |
| US12233418B2 |
Cell capture in microfluidic devices
A capturing of target cells from a biological sample is achieved by inducing a flow of the biological sample in a flow channel (30, 60) of an upstream microfluidic device (1). Target cells present in the biological sample are captured in cell channels (20) of the upstream microfluidic device (1). Once at least a minimum number of target cells are captured in the cell channels (20), the flow of the biological sample in the flow channel is reduced and are verse flow is applied at the upstream microfluidic device (1) to release the target cells captured in the cell channels (20) of the upstream microfluidic device (1) and enable transfer the target cells into cell channels (120) of a downstream microfluidic device (100). |
| US12233417B2 |
Microfluidic chip and microfluidic device for physicochemically treating single cell, and method for physicochemically treating single cell by using microfluidic chip and microfluidic device
Provided is a microfluidic chip for physicochemically treating a single cell whose diameter is 50-400 micrometers. The body of the microfluidic chip comprises a fluidic layer, a pneumatic layer, and an elastic film sandwiched between the fluidic layer and the pneumatic layer; the fluidic layer comprises a switch-back single cell treating and retrieving channel, a first reagent inflow channel, a second reagent inflow channel, a reagent mixing channel, a third reagent inflow channel, a backwash channel, and a negative pressure and waste liquid sharing channel; the pneumatic layer comprises a pneumatic micro-valve group for controlling the opening and closing of each channel in the fluidic layer; the first reagent inflow channel and the second reagent inflow channel are separately connected with the inlet of the reagent mixing channel; the reagent mixing channel, the third reagent inflow channel, the backwash channel, and the negative pressure and waste liquid sharing channel are separately connected with the switch-back single cell treating and retrieving channel; and the third reagent inflow channel and the backwash channel are separately independent channels or share one channel. Also provided is a microfluidic device comprising the microfluidic chip and a method for physicochemically treating a single cell by using the microfluidic chip and the microfluidic device. |
| US12233411B2 |
Detection chip, method of using detection chip and reaction system
A detection chip, a method of using a detection chip and a reaction system are provided. The detection chip includes a first substrate, a micro-chamber definition layer and a heating electrode. The micro-chamber definition layer is located on the first substrate and defines a plurality of micro-reaction chambers. The heating electrode is located on the first substrate and closer to the first substrate than the micro-chamber definition layer, and configured to release heat after being energized. The heating electrode includes a plurality of sub-electrodes, orthographic projections of the plurality of micro-reaction chambers on the first substrate overlap with orthographic projections of at least two of the plurality of sub-electrodes on the first substrate, and the at least two of the plurality of sub-electrodes have different heating values per unit time after being energized. |
| US12233410B2 |
Microfluidic channel backplane and method of manufacturing the same, and microfluidic detection chip
A microfluidic channel backplane includes a base, and a plurality of microfluidic channels, a sample-adding channel and an enrichment channel that are disposed above the base. Each microfluidic channel of the plurality of microfluidic channels includes a first end and a second end. The sample-adding channel is communicated with first ends of the plurality of microfluidic channels. The enrichment channel includes a first enrichment sub-channel and a second enrichment sub-channel. The first enrichment sub-channel is communicated with second ends of the plurality of microfluidic channels, and one end of the second enrichment sub-channel is communicated with the first enrichment sub-channel. |
| US12233408B2 |
Smart storage container for health logistics
Provided herein are methods and related devices for preprocessing a biological sample during transit. The method may comprise the steps of: storing a biological sample in a storage container having walls that defines a storage volume; transporting the storage container with the stored biological sample to a sample processing facility; controlling one or more storage container parameters during the transporting step to initiate preprocessing of the biological sample; wherein the controlling step improves a processing parameter at the sample processing facility. |
| US12233406B2 |
Automated system for high-throughput microinjection of adherent cells
Two or more micropipettes are used to increase a microinjection throughput in an automated system for microinjecting adherent cells on a Petri dish. In the system, a motorized stage carrying the Petri dish sequentially visits the cells according to an optimized injection sequence. The sequence is selected by minimizing a total distance traveled by the motorized stage such that each cell is visited once by one of the micropipettes. Using multiple micropipettes advantageously reduces the minimized total distance over using a single micropipette to thereby increase the throughput. The optimized injection sequence is obtained by solving an equality-generalized traveling salesman problem. Each micropipette is mounted on a motorized micromanipulator. The motorized stage and motorized micromanipulators operate coordinately that each micromanipulator goes down or up during movement of the motorized stage to compensate for unevenness between a focus plane and a moving trajectory of the motorized stage. |
| US12233404B2 |
Exhaust gas purification catalyst
The present invention provides an exhaust gas purification catalyst including a base material and a catalyst layer that is arranged on the base material. The catalyst layer includes a catalyst metal and a carrying material carrying the catalyst metal. The catalyst layer satisfies below: (1) in a pore distribution curve measured by a mercury porosimeter, a peak for the largest pore volume exists within a range of a pore diameter equal to or more than 1 μm and not more than 10 μm; and (2) on an electron microscopy observation image (with a 1000-fold magnification) of a surface of the catalyst layer, when areas of a plurality of voids comprised in the electron microscopy observation image are respectively calculated, a standard deviation for the areas of the plurality of voids is not more than 30 μm2. |
| US12233402B2 |
Cross-coupling reaction catalysts, and methods of making and using same
The present invention provides novel transition-metal precatalysts that are useful in preparing active coupling catalysts. In certain embodiments, the precatalysts of the invention are air-stable and moisture-stable. The present invention further provides methods of making and using the precatalysts of the invention. |
| US12233401B1 |
Lithium absorbent and preparation method therefor
Provided are a lithium adsorbent and a preparation method therefor. A raw material for preparing the lithium adsorbent includes a lithium adsorbent active material and an auxiliary material, where the auxiliary material includes a hydrophilic binder and reinforcing fibers, and the use of the reinforcing fibers and the hydrophilic binder strongly prevents the propagation of brittle cracks caused by volume expansion and contraction of the lithium adsorbent active material during use, significantly increasing the strength and cycle life of the lithium adsorbent, while the use of the hydrophilic binder increases the adsorption rate and capacity of the lithium adsorbent. |
| US12233395B2 |
Method and system for solventless calibration of volatile or semi-volatile compounds
A system for solventless calibration of volatile or semi-volatile compounds and methods thereof. The system includes a fluid path having a first end configured to be operably coupled to a fluid source and a second end configured to be operably coupled to the analytical instrument. A solid sorbent is disposed along the fluid path and is configured to absorb an analyte. The flow of fluid along the fluid path from the first end to the second end causes absorbed analyte to be desorbed from the solid sorbent at a desired concentration to the instrument. |
| US12233394B2 |
Method and fluidized bed granulator for the production of granules from a slurry
A method for granulating a slurry in a fluidized bed granulator having a main longitudinal direction from a seed end where granulation is initiated, to a product discharge end where granules are discharged from the fluidized bed granulator, including at least one fluidized bed compartment, an injection section and a granulation section, separated by a bottom plate including one or more injection nozzles, wherein a feed slurry is provided to the injection section, wherein a first fraction of the feed slurry provided to the injection section is injected into the granulation section through the one or more injection nozzles and a second fraction of the feed slurry, being the remainder of the feed slurry, is passed through the injection section without being injected into the granulation section. A fluidized bed granulator for the granulation of slurries for fertilizer products such as UAS according to the method of the invention. |
| US12233392B2 |
Reactor for endothermic reaction
A solar reactor useful in reaction processes, more particularly, useful in endothermic reaction processes, such as a catalyzed process or an adsorption-desorption process. The reactor comprises a reaction pathway defined by an exterior wall and an interior wall, the exterior wall comprising a solar radiation receiver capable of converting solar radiation into heat and transmitting the heat to the reaction pathway. The reaction pathway has disposed therein, in alternating fashion, a plurality of reactive elements comprised of a catalyst or a sorbent and a plurality of heat transfer elements. |
| US12233391B2 |
Loading nucleic acids onto substrates
Methods, compositions, and systems for distributing nucleic acids into array regions are provided. The methods, compositions, and systems utilize nucleic acid condensing agents to increase efficiency of distribution of the nucleic acids into the array regions. Various methods for facilitating distribution of the nucleic acids to the array regions are provided. |
| US12233390B2 |
Nonfouling compositions and methods for manipulating and processing encapsulated droplets
Compositions for preventing or limiting surface fouling as well as evaporation and methods for their use in air-matrix digital microfluidics (DMF) apparatuses are described. A mobilizing wax material may be used to selectively encapsulate a reaction droplet in the air gap of the apparatus, which permits the at least partially encapsulated reaction droplet to be portable within the DMF apparatus. Additional aqueous droplets may be combined with the encapsulated droplet, by merging with an aqueous droplet having a coating of a secondary material (e.g., an oil or other hydrophobic material) that may allow combining of the droplets. The compositions may be additionally useful in non-DMF applications such as laboratory protocols for hybridization, ligation and amplification. |
| US12233387B2 |
Method and system for the treatment of materials
A system for the treatment of materials, to be selected from between materials in a fluid state (1) and particles suspended in a fluid material (1), comprising at least one upper kinematic pair equipped with two mechanical elements (2a, 2b; 2a, 2c), said kinematic pair being in contact with a material in a fluid state (1) or with particles suspended in a fluid material (1); motor means (5) to generate a pre-set relative velocity (v) between the elements (2a, 2b; 2a, 2c) of said kinematic pair, and tensioning means (8) to subject said kinematic pair to a pre-set pressure (P). |
| US12233386B2 |
Impeller guard
Guard for impellers, methods of using the guards, impeller assemblies including the guards mounted to impellers, impeller systems, and biocontainer systems including the impeller systems, are disclosed. |
| US12233384B2 |
Bubble counter
A bubble counter includes a body. The body is provided with a gas inlet, a gas outlet, a cavity, a water inlet, a water inlet channel, a first check valve and a second check valve. An end of the water inlet channel is connected to the water inlet, and another end of the water inlet channel is connected to the cavity. The first check valve is arranged between the gas inlet and the cavity, and the second check valve is arranged at a connection between the water inlet channel and the cavity. The water inlet channel and the gas outlet are independent from each other. With the bubble counter, it is not required to turn off or disassemble the bubble counter, water can be added at any time and gas leakage can be prevented. |
| US12233380B2 |
Environmental control system utilizing an anion conducting membrane
An environmental control system employs an electrolysis cell utilizing an anion conducting membrane. A power supply is coupled across the anode and cathode of the electrolysis cell to drive reactions to reduce oxygen and/or carbon dioxide in an output gas flow. A cathode enclosure may be coupled with the electrolysis cell and provide an input gas flow and receive the output gas flow. A first electrolysis cell may be utilized to reduce the carbon dioxide concentration in an output flow that is directed to a second electrolysis cell, that reduces the concentration of oxygen. The oxygen and/or carbon dioxide may be vented from the system and used for an auxiliary purpose. An electrolyte solution may be configured in a loop from a reservoir to the anode, to provide a flow of electrolyte solution to the anode. Moisture from the cathode may be collected and provided to the anode. |
| US12233377B2 |
Hydrogen gas supply apparatus and hydrogen gas supply method
A hydrogen gas supply apparatus includes a compressor configured to compress hydrogen gas and supply the compressed hydrogen gas toward a pressure accumulator which accumulates the hydrogen gas, a first adsorption column disposed between the discharge port of the compressor and the pressure accumulator and configured to include the first adsorbent for adsorbing impurities in the hydrogen gas discharged from the compressor, a first valve disposed between the discharge port of the compressor and the gas inlet port of the first adsorption column, a second valve disposed between the gas outlet port of the first adsorption column and the pressure accumulator, a return pipe configured to branch from between the first valve and the gas inlet port of the adsorption column and connect to the suction side of the compressor, and a second adsorption column disposed in the middle of the return pipe. |
| US12233376B2 |
Surface-modified carbon and sorbents for improved efficiency in removal of gaseous contaminants
A material, and filters and other structures exposed to flowing gas that have the material therein, which removes VOCs, such as formaldehyde, from the gas. The material is a porous sorbent impregnated by a metal oxide, such as manganese oxide (MnOx) nano particles. The sorbent may be activated carbon, and the manganese oxide may catalyze formaldehyde to water and carbon dioxide while the carbon may adsorb formaldehyde, both mechanisms of which remove the VOC from the air to prevent or reduce inhalation of the same by humans. The material may be combined with an untreated sorbent or sorbent treated with ionic alkaline salts. |
| US12233375B2 |
Filtration systems with proactive pulse cleaning
Included herein are filtration systems that can proactively pulse clean filter elements in response to anticipated changes, such as anticipated changes in filtration performance or anticipated changes in filtration system demand. In an embodiment, a filtration system is included having a filter element mount for a filter element, a compressed gas supply, and a valve, wherein opening the valve results in a pulse of gas directed at the filter element. A control circuit can control the valve. A communications circuit can receive data related to an anticipated change, such as data regarding an anticipated change in filtration performance and/or data regarding an anticipated change in filtration system demand. The control circuit can execute operations based on the anticipated change data such as adjusting a pressure drop threshold and initiating proactively opening the valve in the absence of a pressure drop threshold being crossed. Other embodiments are also included herein. |
| US12233371B2 |
Passive inline annular phase separator
A phase separator includes an inlet of an inlet duct to receive two-phase flow from a two-phase flow source that is in line with the inlet duct. The two-phase flow includes gas and liquid. The phase separator also includes a liquid permeable membrane arranged at an outlet of the inlet duct to pass the liquid for capture while diverting the gas to result in an annular flow of the gas around the liquid permeable membrane. An outlet of an outlet duct outputs the gas that is separated from the liquid and that results in the annular flow of the gas. |
| US12233370B2 |
Filter element with integral breather filter
The technology disclosed herein relates to a filter element having a first endcap, a second endcap, and filter media extending between the first endcap and the second endcap. The filter media defines a central opening and is coupled to the first endcap and the second endcap. A filter cover is coupled to the first endcap, and a breather filter is integral to the filter cover. The breather filter defines a first flow face and a second flow face. The filter element defines an airflow pathway from ambient environment through the first flow face and the second flow face. |
| US12233365B2 |
Tailing pond remediation
Various embodiments of the present disclosure can include a system for filtering of contaminated fluid. The system can include a fiber manufacturing plant. The system can include a filter system which utilizes a fiber filter produced in the fiber manufacturing plant to clean and recycle a contaminated fluid. |
| US12233364B2 |
Fuel filter cartridge with keyed profile
A filtration system comprises a filter head assembly comprising an outlet slot, valve element, and latch element. The valve element is in fluid communication with the outlet slot and includes an open position and a closed position. In the open position fluid flow travels through the outlet slot. In the closed position fluid flow is prevented through the outlet slot. The latch element is configured to lock the valve element in the closed position. The filtration further comprises a filter cartridge structured to engage the filter head assembly. The filter cartridge comprises a first and second filter end. The filter cartridge comprises filter media and a keyed element disposed on the first filter end. The keyed element is structured for engagement of the latch element, wherein the engagement unlocks the valve element causing the valve element to be in the open position. |
| US12233362B2 |
Energy saving and emission reduction system for chemical separation and purification process
An energy saving and emission reduction system for chemical separation and purification process is disclosed. The chemical separation and purification process includes a synthesis section and/or a distillation section and/or a recovery section. The energy saving and emission reduction system includes an energy comprehensive utilization maximizing energy saving module. The energy comprehensive utilization maximizing energy saving module comprehensively evaluates the chemical separation and purification process, and acquires a lowest energy consumption value according to initial and final material flow parameters. Then energy integration optimization and energy saving technical modification are performed on the synthesis section and/or distillation section and/or recovery section according to the lowest energy consumption value. The disclosure involves a comprehensive and extensive energy saving and emission reduction system for chemical separation and purification process, and has achieved good environmental benefits. |
| US12233361B2 |
Filter insert and guide arrangement
A filter insert is provided for being removably arranged in a filter housing and includes a first actuation arrangement positioned at a first end of the filter insert, wherein the first actuation arrangement is adapted for being actuated by a corresponding second actuation arrangement of a filter housing lid for controlling a relative axial movement between the filter insert and the filter housing lid. |
| US12233360B2 |
Liquid filter
In one or more embodiments, a liquid filter 100 to filter fuel or lubricant is provided. The liquid filter 100 includes a housing 102 extending along the vertical axis XX′. The housing 102 has a cylindrical shape and includes a top end cap 104 and a bottom end cap 106 provided at both ends. The top end cap 104 and the bottom end cap 106 are integratedly formed in one piece with the housing 102. The top end cap 104 includes an outlet 108 for allowing outflow of filtered liquid from the housing 102. A hand priming pump 110 is functionally attached to the outlet 108 of the top end cap 104 for easing priming. The bottom end cap 106 includes an inlet 112 for allowing inflow of dirty liquid inside the housing 102. |
| US12233356B2 |
Process for preparing extracellular vesicles
The present disclosure relates to multistep chromatographic methods for preparing extracellular vesicles (EVs). The methods were demonstrated to be effective in preparing highquality EVs in a large scale. The methods enable preparation of EVs for therapeutic and diagnostic applications, and isolation and/or sub-fractionation of EVs with desired properties for specific use. |
| US12233355B2 |
Methanol-based extraction of psychoactive alkaloids from fungus
This invention relates to the extraction of psychoactive compounds from fungus for use in medicine. Raw fungus is dried and ground. The solvent used for extraction is methanol or a hydro-methanol mixture, an acidic hydro-methanol mixture, or an alkaline hydro-methanol mixture. The extraction slurry is filtered and pH-adjusted if necessary. The methanol in the solvent is then completely evaporated and water added back, where necessary, to form a concentrated slurry. The concentrated slurry is then standardized to provide a known concentration of the psychoactive alkaloids that have been extracted. The standardized slurry may then be dried to result in a powdered extract with a precisely defined purity of psychoactive compounds. |
| US12233353B2 |
Bubble machine
The present disclosure provides a bubble machine. The bubble machine includes a shell, a bubble forming part, and a motion and liquid introduction member, wherein the bubble forming part is arranged on the shell and is provided with a plurality of bubble forming units; the motion and liquid introduction member is arranged on the shell and is provided with a liquid inlet and a liquid outlet; the liquid inlet is configured to obtain bubble liquid and introduce the bubble liquid into the liquid outlet; the liquid outlet is arranged in a manner of corresponding to the bubble forming part; and the motion and liquid introduction member is configured to be driven to move to introduce the bubble liquid at the liquid outlet into the plurality of bubble forming units. |
| US12233352B2 |
Splicing animal building block toy
Described herein is an assembled building block toy, and in particular to a splicing animal building block toy which consists of several different body part building blocks of different types of animals. The building blocks are divided into a head part building block, a body part building block, a limbs part building block, and a combined part building block, which are body parts of different types of animals. The connection structures at the splicing positions have the same design method, size and shape, making it possible to realize the mixed splicing use of building blocks of different types of animals and splice a variety of variant models. |
| US12233347B2 |
Target game device
A target game device for use in conjunction with a toilet includes a target portion with sensors to detect a urine stream and logic to allocate points based on accuracy. A user interface provides engaging and entertaining feedback to motivate users to improve their aim. |
| US12233342B2 |
Fantasy sports data analysis for game structure development
In an aspect, fantasy sports data is analyzed to generate and/or manage the delivery of and user experience of fantasy sports games and contests, including timing and payout structure(s) for short-term fantasy contests, such as daily, weekly, etc. fantasy sports contests, that motivate and appeal to contestants and is/are reasonably structured and concisely represented. In yet another aspect, a daily fantasy contest system is provided to automatically adjust to user demand without overshooting profitable levels and offer a variety of different contests, as well as offer contests with guaranteed and non-guaranteed payouts. |
| US12233340B2 |
Method and apparatus for controlling virtual character in virtual environment, device, and medium
Embodiments of this disclosure include an information processing method. In the method, a picture of a virtual environment is displayed. The picture includes a target region located in the virtual environment where the target region is adjacent to a neighboring region in the virtual environment. In response to a first movement instruction, a virtual character is controlled to enter the target region from the neighboring region by processing circuitry of an information processing apparatus. A first movement speed of the virtual character in the neighboring region is higher than a second movement speed of the virtual character in the target region. The information processing apparatus and non-transitory computer-readable storage medium counterpart embodiments are also contemplated. |
| US12233332B2 |
Remote multiplayer interactive physical gaming with mobile computing devices
Methods and systems for remote multiplayer gameplay are disclosed. An example method can include joining a multiplayer interactive physical game including first and second players competing in an activity; capturing a first game video of a first player in a first play of the multiplayer interactive physical game, using a first camera on a first mobile computing device in a first gaming area; determining a first object flow associated with the first player from the first game video, by performing an algorithm on one or more frames of the first game video to detect one or more key points of the first player; generating a first analytic based on the first object flow; receiving a second analytic associated with the second player in a second gaming area; and generating a feedback to the first player based on the first analytic or the second analytic. |
| US12233331B2 |
Card holding and playing system
Certain aspects are directed to a portable and compact card holding and playing system comprising a card caddy with a detachable rotating mechanism, a flexible retaining device with at least one weighted element, a plurality of retaining discs, and a game plate using a number of flexible retaining mechanisms. The game plate is single and/or trifold with the trifold plate comprising a ferrous core with top and bottom laminate materials connected via hinges. The retaining disc is stackable, which can be placed on a number of cards or on each other. The card tray is preferably detachable from a rotatable base with a center divider that includes a magnetic component used to securely attach the card tray to the magnets embedded in the flexible retaining device and the base, thus allowing the kit to operate via magnetic and gravitational forces and be used in the presence of wind, turbulence or on uneven playing surfaces. |
| US12233328B2 |
Athletic monitoring garment with non-transmitting, non-receiving sensor systems and methods
A garment including a breath sensor module. The breath sensor module includes a stretchable sensor configured to respond to at least one of expansion and contraction of a torso of an individual wearing the garment. The breath sensor module also may include an electronics module. The electronics module includes, for example, a processor and a haptic feedback device. In response to the processor determining that the individual's breathing meets predetermined criteria based on the response of the stretchable sensor, the haptic feedback device produces haptic feedback such that the individual is reminded to breathe. Further, the breath sensor module does not include a transmitter or a receiver configured to transmit or receive data outside of the breath sensor module. Advantageously, this allows for streamlined use, and less-intrusive reminders to the individual wearing the garment, without the complexities of signal transmission or receiving. |
| US12233325B2 |
Court edge enhancement
An apparatus or system for enhancing an edge of a sporting court may include a first surface configured to engage with a surface of the sporting court and a second surface coupled to the first surface and configured to receive a ball and retain the ball in engagement with the second surface. The second surface may comprise a plurality of sub-surfaces, wherein one of the sub-surfaces may comprise a radial curve or at least one peak and at least one trough. The apparatus may comprise a retaining mechanism configured to retain at least one of the first surface or the second surface adjacent a court edge barrier. |
| US12233322B2 |
Training device
A training device for teaching and practicing ball handling skills for basketball players or persons training for sports, the training device including stanchions positionable on a floor using attachment members, such as suction cups, or a flexible resilient layer. A crossbar extends between the stanchions. Flexible elements can be used to connect the stanchions to the suction cups. The lengths of the stanchions and crossbar can be adjustable to set the height of the crossbar above the floor and the separation of the crossbars. Detents can allow for adjustably fixing the lengths. |
| US12233321B1 |
Collapsible devices for improving playability and marketability of net based sports
A portable net system for net games is disclosed which provides for rapid assembly, lightweight construction, durability against damage while assembling and playing, and also provides enhancements inherent in the design which allow for improved marketing and advertising during tournaments. The net functions through having a bow-shaped tensioning rod reacting against the net top-tape to provide primary shape, net tension and height control. A vertical post at each distal end is attached to the foldable feet to provide lateral stability, and these are attached to the net via insertion into the net end-band and durably connected via the rigid bow end-connectors. Removable end-panels at each end net termination provides for a self-tensioned surface where advertising and sponsor labels may be attached. |
| US12233318B2 |
Golf club heads
Golf club heads are provided for selectively increasing or optimizing the coefficient of restitution (COR) at likely impact locations on the striking face of the golf club heads, while simultaneously maintaining characteristic time (CT) below a threshold value in those likely impact locations. By analyzing historical impact locations of a large cross-section of golfers, golf club head COR values can be increased or optimized in preferential locations on the striking face, such as using weighting factors for a predefined set of locations on the striking face. Therefore, instead of increasing COR uniformly across the face and/or increasing COR at impact locations on the face where golfers are unlikely to strike the golf ball, the sweet spot of the golf club head can be increased at the impact locations where golfers typically strike the golf ball. |
| US12233316B2 |
Fold-up trampoline, method for folding up a trampoline and method for tensioning a jumping bed
A fold-up trampoline, having at least three posts arranged in parallel to one another and to a vertical direction (V), wherein a jumping bed is tensioned between the at least three posts, at least three bracing struts which connect a respective other pair of posts arranged next to one another in a peripheral direction (U) of the trampoline and stabilize these posts in a horizontal direction (H), wherein each bracing strut is foldably mounted on both posts arranged next to one another in the peripheral direction (U) and has at least one central joint, which is provided in a central region (B1) of the bracing strut, wherein all the posts arranged next to one another in the peripheral direction (U) can be moved towards one another in order to fold up the trampoline. |
| US12233310B2 |
Treadmill platform folding mechanism of treadmill
The present disclosure provides a treadmill platform folding mechanism of a treadmill. The treadmill platform folding mechanism of the treadmill includes: two base frames, running decks, and a hinge; opposite openings are formed in two ends of opposite sides of the two base frames; one running deck is fixed on each of the two base frames; the hinge includes two hinge bodies; each hinge body includes a hinge seat, a hinge shaft, a hinge piece, and a sliding shaft; one end of the hinge seat of the single hinge body is plugged into the opening of the corresponding base frame, and a bolt vertically passes through the base frame and the hinge seat for fixing; the hinge shafts are arranged on upper sides of unfixed ends of the two hinge seats; sloping-upward strip-shaped through slots are also formed in the two hinge seats. |
| US12233303B2 |
Carriage assembly and weightlifting assembly including a carriage assembly
An adjustable carriage assembly includes a carriage defining a passage configured to receive a frame member therethrough such that the carriage is moveable along the frame member, and a locking structure configured for engaging the frame member to lock the carriage in position relative to the frame member. The locking structure includes a main pin and an auxiliary pin connected to the carriage that are each moveable between a locked position, where the respective pin extends into the passage and is configured to engage the frame member to lock the carriage in position, and an unlocked position, where the respective pin is retracted from the passage and is configured to disengage from the frame member. The carriage may also include a first portion and a second portion, where a space is defined between the first and second portions, and the second portion is adjustable with respect to the first portion. |
| US12233302B2 |
Modular exercise weight system
The device is a modular exercise weight system comprising at least one outer containing bag which can contain at least one particle filled weight bags. The user lifts the outer containing bag for exercise. Multiple outer containing bags may be affixed to a bar and the bar may be lifted for exercise. The outer containing bags may be affixed to an element of a machine and the element of the machine may be lifted or manipulated for exercise. |
| US12233300B1 |
Yoga block system
A yoga block system that is comprised of a plurality of props wherein the props are configured to be releasably secured in order to facilitate creation of a multitude of configured props having various shapes and sizes. The prop of the present invention is provided in various shapes and sizes. At least one surface of the prop includes a magnet secured therein. The magnet can be secured so as to be in one of three positions; flush, recessed or extended. The magnets of the props are aligned in a pattern so as to facilitate releasable securing of a first prop to a second prop. The prop can further be configured with a peg extending outward from a surface thereof wherein the peg is operable to be inserted into a hole formed in a surface of a prop that is designed to be releasably secured thereto. |
| US12233298B2 |
Multi-purpose pump
The present invention discloses an improved compressed air foam pumping/generation system in which the compressed gas that is used to drive a pumping system is re-utilized and introduced into the outlet manifold to more efficaciously generate a compressed gas foam. A further improvement could include a three-way valve which controls the flow of the compressed gas so that the present invention could be used to generate CAF, aspirated foam (with use of an appropriate nozzle), gels or operate as a simple pump. Additional optional components include a check valve and flexible connection material. |
| US12233291B2 |
Face mask with smart features and functions
Masks for being worn by a person are described herein. The masks include a shell configured to cover a nose and a mouth of the person, at least a portion of the shell having sufficient transparency to provide for visual observation of the mouth of the person when the person is wearing the mask. The shell includes an inhale port configured to provide for air to pass from an environment into a cavity defined by the shell when the person wearing the mask inhales and an exhale port configured to provide for air to pass from the cavity to the environment when the person wearing the mask exhales. The masks also include a retaining element coupled to the shell for retaining the mask on the person. |
| US12233281B2 |
Therapeutic device for painful inflammatory pathologies and for neuro-muscular and neuro-postural modulation
The therapeutic device of the invention consists of a support to be placed on the skin of a patient and made of specific nanocrystals, which when properly activated, produce electromagnetic emissions that have beneficial effects on inflammatory, painful pathologies, and neuro-muscular and postural modulations of the patient. |
| US12233280B2 |
Adhesive phototherapy method, system, and devices for acne
A phototherapy device, system, and method for treating acne and/or acne scarring, includes a light emitting device configured and arranged to emit light from a bottom surface thereof; and an attachment portion having an aperture therethrough configured to permit light through. The attachment portion is configured to retain the device to a user's skin and bathe the skin with phototherapeutic light from the light emitter. Attachment of the device may be preceded with the application of synergistic fluid, ointment, gel, cream, lotion, foam, soap, or other solutions which may or may not consist of known topical acne treatment agents, augment device attachment to the skin, and/or have photodynamic properties. The light emitted may be any wavelength, combinations of wavelengths, intensity, pulse frequency, and exposure duration. |
| US12233278B2 |
Laser system for enhancing remineralization and strength of hard tissue
A laser-based system and method for treatment of hard tissue enhances remineralization and fluoride uptake to improve resistance to demineralization. The system can include a laser source, an optic, and a controller for controlling the laser source and/or the optic to deliver radiation to a treatment region with desirable characteristics (e.g., to remove carbonate without damaging the tissue surface). In some cases, the system includes a handpiece having an optical element (e.g., a lens) mounted within a replaceable cartridge and adapted to modulate a laser beam to render the beam non-ablative, prior to the laser beam's delivery to the treatment region. In some embodiments, treatment with the laser can be combined with a fluoride treatment for enhanced therapeutic effect. |
| US12233269B2 |
Power controls for an implantable device powered using ultrasonic waves
Method and system embodiments for controlling power provided to a device implantable in a subject are described. In some embodiments, a method is performed at the implantable device to receive, from an interrogator, powering ultrasonic waves having a wave power. Then, energy from the powering ultrasonic waves is converted into an electrical signal to power the implantable device. Information that indicates whether more power or less power should be transmitted to the implantable device is transmitted to the interrogator. |
| US12233264B2 |
Hearing device and method of using same
Various embodiments of a hearing device and a method of using such device are disclosed. The hearing device includes a housing having an inner surface and an outer surface, electronic components disposed within the housing, and a port disposed in the housing and extending between a first end at the outer surface of the housing and a second end disposed within the housing, where the port is acoustically connected to at least one of a speaker or a microphone of the electronic components. The hearing components also include a controller that is electrically connected to a sensor and that is adapted to detect a change in capacitance of the sensor, where the change in capacitance is associated with debris at least partially occluding the port. |
| US12233260B2 |
Electroosmotic tissue treatment
Apparatus is provided that includes a first electrode, configured to be implanted at a first anatomical site in a nucleus pulposus of an intervertebral disc of a subject, and a second electrode, configured to be implanted at a second anatomical site outside the nucleus pulposus of the disc. A control unit is configured to detect a pressure difference between the first and the second anatomical sites by detecting a streaming voltage between the first and the second electrodes, and, in response to the detected pressure difference, drive fluid between the nucleus pulposus and outside the nucleus pulposus by applying a treatment voltage between the first and the second electrodes. Other embodiments are also described. |
| US12233259B2 |
Transvascular medical lead
A medical electrical lead and methods of implanting medical electrical leads in lumens. Leads in accordance with the invention employ preformed biases to stabilize the lead within a lumen or lumen and to provide feedback to lead implanters. |
| US12233255B2 |
Hearing percept parameter adjustment strategy for a hearing prosthesis
A prosthetic system, comprising a first sub-system configured to evoke a hearing percept based on a first principle of operation, and a second sub-system configured to evoke a hearing percept based on at least one of the first principle of operation or a second principle of operation different from the first principle of operation, wherein the first and second sub-systems are configured to independently process respective inputs indicative of an ambient sound to harmonize an estimated recipient perception of magnitude of a property of the respective evoked hearing percepts. |
| US12233250B2 |
Device for inductive energy transmission into a human body and use thereof
The invention relates to a device (10; 10a) for inductive energy transfer into a human body (1), having a transmitter unit (11) with a housing (12), in which at least one transmitter coil (14) is arranged, wherein the housing (12) comprises a contact surface (23), which is configured in order to be brought into surface contact with the body (1), and a receiver unit (20) that can be positioned in the body (1) with a receiver coil (21), wherein a heat-insulating element (26) and a heat-conducting element (30; 30a) are arranged between the transmitter coil (14) and the body. |
| US12233248B2 |
Smart injector
A device that regulates, monitors, and provides data on the progress of a large-volume injector during its injection sequence. The device comprises an injector and a monitor assembly. The injector has a syringe having a plunger, and a biasing device that biases the plunger through the syringe. The monitor assembly comprises a resistance unit configured to resist movement of the plunger, a gear connected to the plunger by the resistance unit, and a control unit configured to monitor the position, and regulate the rotation, of the gear. Wherein linear movement of the plunger causes the gear to rotate so that the control unit generates information on the position of the plunger. |
| US12233247B2 |
Injection device
An injection device includes an elongated housing extending along a longitudinal axis, a piston rod to operably engage with a piston of a cartridge filled with the medicament, a dose tracker selectively operably engageable with the piston rod, wherein the dose tracker is longitudinally displaceable relative to the housing from an initial position in a proximal direction towards at least a first activation position for setting of the dose and wherein the dose tracker is longitudinally displaceable relative to the housing in a distal direction from the at least first activation position towards the initial position for dispensing of the dose, a spring to urge the dose tracker in the proximal direction relative to the housing, an interlock to lock the dose tracker in the initial position relative to the housing, and a release member to release the interlock. |
| US12233245B2 |
Shock absorber for injection devices
The present application relates to shock absorbers for injection devices. According to a first aspect, this specification discloses an injection device including: a medicament container; a stopper translatably disposed within the medicament container; and a plunger rod including: a plunger rod body; and a shock absorber, wherein the plunger rod is operable to displace the stopper; and wherein the shock absorber contacts the stopper during displacement of the stopper by the plunger rod, thereby reducing an impact force between the plunger rod and the stopper. |
| US12233244B2 |
Autoinjector
An autoinjector includes a case adapted to hold a medicament container having a needle telescopically coupled to the case and movable between a first extended position relative to the case in which the needle is covered and a retracted position relative to the case in which the needle is exposed. The autoinjector includes a plunger rotationally and slidably disposed in the case rotatable relative to the case between a first rotational position in which the plunger is engaged to the case and a second rotational position in which the plunger disengages the case engages the plunger to rotate the plunger from the first rotational position to the second rotational position when the needle shroud translates from the first extended position to the retracted position. The autoinjector includes a cap removably coupled to the case includes at least one compliant case beam adapted to releasably engage at least one aperture in the case. |
| US12233241B2 |
Methods and systems to validate physiologic waveform reliability and uses thereof
Methods and systems to validated physiologic waveform reliability and uses thereof are provided. A number of embodiments describe methods to validate waveform reliability, including blood pressure waveforms, electrocardiographic waveforms, and/or any other physiological measurement producing a continuous waveform. Certain embodiments output reliability measurements to closed loop systems that can control infusion rates of cardioactive drugs or other fluids in order to regulate blood pressure, cardiac rate, cardiac contractility, and/or vasomotor tone. Further embodiments allow for waveform evaluators to validate waveform reliability based on at least one waveform feature using data collected from clinical monitors using machine learning algorithms. |
| US12233238B2 |
Diabetes therapy based on determination of food item
Devices, systems, and techniques for guiding therapy delivery to a diabetes patient is described. Some devices, systems, and techniques proactively monitor the patient's food consumption and (if needed) adapt the patient's diabetes therapy accordingly. In one example, a system comprises one or more sensors configured to capture a representation of the object, and processing circuitry configured to determine data corresponding to the representation of the object, wherein the data comprises information identifying the object as a particular food item; generate food item information based on the information identifying the object as the particular food item, wherein the food item information comprises at least one of nutrition information or volume information of the particular food item, generate therapy information for the patient based on the food item information, and output content indicative of at least one of the therapy information or the food item information. |
| US12233235B2 |
Patch-sized fluid delivery systems and methods
A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device. |
| US12233231B2 |
Vented connector for medical fluid vessels and tapered plug
A connector for medical fluid vessels includes a fluid-seal fitting such as a male plug defining a lumen and mating with a cooperating connector, a mechanical fastener such as a screw thread for mating with the cooperating connector, and an outer housing positioned around the plug to form an annular space. A cap can be provided with a fluid-seal fitting such as a male plug for mating with the lumen of the connector. In example embodiments, the male plug is tapered and can comprise one or more projections for sealingly engaging with the lumen of the connector. According to some example embodiments, the cap can be tethered to the connector. |
| US12233230B2 |
Single-use disposable set connector
A medical connector for providing a sterile connection between a multi-use portion and a single-use portion of a fluid delivery system is provided. The medical connector includes a fluid inlet port configured for removable engagement with a connection port of a multi-use disposable set (MUDS) to establish a fluid connection therewith and a waste outlet port configured for removable engagement with a waste inlet port of the MUDS to establish a fluid connection therewith. A patient fluid line is connected, at a first end, to the fluid inlet port and connected, at a second end, to the waste outlet port. Fluid flow through the patient fluid line is unidirectional from the first end to the second end. The patient fluid line is configured for being disconnected from the waste outlet port for delivering fluid to a patient. A multi-fluid delivery system having the medical connector and MUDS is also provided. |
| US12233228B2 |
Methods and devices to prevent premature birth
Methods and devices to affect types, proportion, quantity, distribution, or proliferation of microorganisms within a female reproductive system. |
| US12233224B2 |
Persistent perfusion sheath
A persistent perfusion sheath assembly can be used for the passage of an intravascular medical device while maintain a flow passage in the vessel. The sheath assembly passes through an arteriotomy and can include a first lumen configured for the passage of a medical device, a second lumen configured to allow a flow of fluid from a location in the blood vessel upstream of the arteriotomy to a location downstream of the arteriotomy. The sheath assembly can further include a stylet, a sleeve or an additional sheath configured to selectively open and close the flow of blood between upstream and downstream of the arteriotomy. The sheath assembly can further include a closure device distal of the arteriotomy, the closure device configured to control blood flow through the arteriotomy. |
| US12233221B2 |
Telescoping catheter
A telescoping catheter including an elongated tubular member having a proximal end, a distal end, and a passageway extending between the proximal end and the distal end. The tubular member includes a first tubular segment and a second tubular segment. The first tubular segment and the second tubular segment are slidable relative to one another to vary a length of the tubular member. The first tubular segment includes a first connector mateable with a second connector of the second tubular segment to selectively maintain the first and second tubular segments in an extended position. The second tubular segment includes a second proximal end that is mateable with a handle. |
| US12233213B1 |
Inhaled internal heat/thermal conduction therapy for esophageal cancer
A method for treating esophageal cancer in situ with heated air that can be inhaled through a face mask, at an elevated temperature less than sauna air temperatures and at a constant positive air pressure. The inhaled heated air will heat the very thin tracheoesophageal party wall sheath membrane between the esophagus and the respiratory trachea in the throat. The tracheoesophageal party wall sheath membrane therefore can heat the esophageal cancer tumor adjacent to the heated trachea and tracheoesophageal party wall sheath membrane. The heated air will be inspired/inhaled through the mouth and into the trachea/windpipe. Then the trachea and trachea tube under heated constant positive pressure will then transfer heat through and to the esophagus wall, and esophagus and tumor. The heat from the heater air inspiration through the trachea migrates/transmits/disperses across the membrane separating the trachea/windpipe from the esophagus and hits the esophagus with heat. |
| US12233210B2 |
Method of delivering variable ventilation with AVAPS
A method for controlling a ventilator to provide variable volume (VV) with average volume assured pressure support (AVAPS), including: producing a VV target volume using a VV distribution function; producing a volume error Verror that is the difference between the VV target volume and a measured volume of the previous breath; scaling the volume error Verror; producing a VV target difference as the difference between VV target volume and the VV target volume of the previous breath; producing a modified volume error by adding the VV target difference to the scaled volume error Verror; producing a delta pressure support ΔPS based upon the modified volume error and a dynamic compliance; and producing a current pressure support value based upon the delta pressure support ΔPS and the pressure support value of the previous breath. |
| US12233209B2 |
Ventilation treatment device and ventilation-control method
A tube assembly includes a first tube piece and a second tube piece. The first tube piece includes an inlet end connecting a gas source and an outlet end connecting the second tube piece. The first tube piece includes a discharging hole that is configured so that, in a connecting state, the discharging hole is closed to make the gas to enter the second tube piece, in the separating state, the discharging hole is opened to make the gas to be discharged outside from the discharging hole. The tube assembly includes a valve member that is configured so that, in the connecting state, the valve member opens the outlet end of the first tube piece to make the gas to enter the second tube piece, and in the separating state, the valve member closes the outlet end to make the gas to be discharged outside from the discharging hole. |
| US12233208B2 |
Radio-frequency identification (RFID) authentication system for aerosol delivery devices
A control body and cartridge that are coupleable with one another to form an aerosol delivery device are provided. The control body comprises a control component and an RFID reader contained within at least one housing. The cartridge comprises at least one heating element and an RFID tag contained within at least one housing. The RFID reader of the control body is coupled to the control component of the control body and configured to communicate with the RFID tag of the cartridge upon coupling of the control body with the cartridge. The control component of the control body is configured to authorize the cartridge for use with the control body based at least in part on communication between the RFID reader and the RFID tag. |
| US12233205B2 |
Thermal modulation of an inhalable medicament
A thermally modulating inhalable medicament delivery device may deliver an inhalable medicament as an aerosol, vapor, or partial aerosol and partial vapor mixture to a subject. The inhalable medicament may be delivered to a targeted location in an airway of the subject. Various other devices, systems, and methods for delivering an inhalable medicament to a subject are also disclosed. |
| US12233204B2 |
Nicotine powder delivery system
A nicotine powder delivery system includes an inhaler article and a nicotine powder capsule disposed within the inhaler article. The nicotine powder capsule rotates about a longitudinal axis when air flows through the inhaler article. |
| US12233202B2 |
Vaporizing unit with dry wick indication
A personal vapor inhaling unit is disclosed. An electronic flameless vapor inhaler unit that may simulate a cigarette has a cavity that receives a cartridge in the distal end of the inhaler unit. The cartridge brings a substance to be vaporized in contact with a wick. When the unit is activated, and the user provides suction, the substance to be vaporized is drawn out of the cartridge, through the wick, and is atomized by the wick into a cavity containing a heating element. The heating element vaporizes the atomized substance. The vapors then continue to be pulled by the user through a mouthpiece and mouthpiece cover where they may be inhaled. |
| US12233201B2 |
Inhaler system
Provided is a system comprising an inhaler. The inhaler comprises a use determination system. The use determination system is configured to determine a parameter relating to airflow during a use of the inhaler by a subject. The use determination system also assigns a time to the use. The system also comprises a user interface, and a processing module. The processing module is configured to determine inhalation information from the parameter, and control the user interface to issue a notification that the inhalation information is available. The notification is issued at a notification time. The processing module is configured to implement a deliberate time delay such that the notification time is delayed relative to the time assigned to the use. |
| US12233196B2 |
Systems and methods for operating a wound therapy device in stealth mode
A negative pressure wound therapy system can include a housing and a source of negative pressure enclosed by the housing configured to aspirate fluid from a wound covered by a wound dressing. The system can have one or more visual indicators visible at the exterior surface of the housing, configured to indicate status of the system to a user. The system can also have electronic circuitry enclosed by the housing, the electronic circuitry configured to automatically, or in response to a request from the user, transition the system between at least a first operational state and a second operational state, wherein in the second operational state the one or more visual indicators are configured to not emit any light or to emit light at one or more wavelengths that are not visible to naked human eye. |
| US12233195B2 |
Negative pressure wound therapy apparatuses and methods for using the same
Embodiments of negative pressure wound therapy systems, apparatuses, and methods for operating the systems and apparatuses are disclosed. In some embodiments, a medical device is configured to detect an identity of a patient-contacting disposable connected to the medical device. The medical device automatically modifies one or more operational parameters of the medical device based on the identity of the patient-contacting disposable connected to the medical device. The medical device can include a user interface and modify automatically available selections in the user interface based on the identity of the patient-contacting disposable connected to the medical device. |
| US12233194B2 |
Systems for eliminating and/or reducing aerosol emissions from a heater/cooler
A system including tubing and a filter configured to be fluidly coupled to a vacuum source and to a heater/cooler unit by the tubing. The filter includes a filter container having negative air pressure in the filter container provided by the vacuum source to pull aerosol from the heater/cooler unit into the filter container and eliminate and/or reduce the aerosol emitted from the heater/cooler unit. |
| US12233192B2 |
Cell washing apparatus
A cell washing apparatus is provided to wash a cell-containing fluid. The apparatus is arranged to exchange one or more exchangeable entities from a cell-containing first fluid, and comprises, a first fluid conduit and a second fluid conduit, the second fluid conduit separated from the first fluid conduit by a semi-permeable membrane disposed therebetween; the first fluid conduit having a first fluid inlet and a first fluid outlet, the first fluid conduit arranged to transport the first fluid in a first direction between the first fluid inlet and the first fluid outlet; the second fluid conduit being arranged to house a second fluid; wherein the semi-permeable membrane comprises a plurality of pores arranged to permit transport of said one or more exchangeable entities from the first fluid to the second fluid; wherein the one or more exchangeable entities comprise free haemoglobin and/or blood plasma; and wherein the first fluid is whole blood isolated from a human body, or packed red blood cells. The cell washing apparatus of the present invention aims to solve the problem of harmful species that accumulate in a cell-containing fluid (such as, for example, transfusion blood) during storage and other applications, in which it is desired to transfer red blood cells to a clean suspending liquid. |
| US12233189B2 |
Smart artificial lung and perfusion systems
An artificial lung system for a patient having a membrane lung system having an gas inlet, a blood inlet, a blood outlet, and an exhaust; a gas system operably coupled to the gas inlet of the membrane lung system; a gas phase CO2 sensor disposed downstream of the exhaust of the membrane lung system and monitoring an exhaust gas CO2 (EGCO2) level and/or an blood oxygen saturation sensor disposed upstream of the blood inlet of the membrane lung system and monitoring a blood oxygen saturation level; and a feedback controller receiving the CO2 signal and/or blood oxygen saturation signal and outputting a control signal to control gas flow and/or blood flow. |
| US12233184B2 |
Dimethylacrylamide (DMAA) hydrogel for expansion microscopy (ExM)
The invention provides a method for preparing an expanded cell or tissue sample suitable for microscopic analysis. Expanding the sample can be achieved by binding, e.g., anchoring, key biomolecules to a DMAA-TF polymer network and swelling, or expanding, the polymer network, thereby moving the biomolecules apart as further described herein. As the biomolecules are anchored to the polymer network isotropic expansion of the polymer network retains the spatial orientation of the biomolecules resulting in an expanded, or enlarged, sample. |
| US12233182B2 |
Instant underwater bio-adhesive containing catechol moieties and water-resistant cholesterol
A novel bio-adhesive suitable for in vivo and/or underwater medical use is disclosed. The bio-adhesive includes base polymers conjugated to hydrophobic moieties for imparting water-resistance and/or to phenolic moieties for enhancing adhesion to biological tissues. The bio-adhesive exhibits low toxicity and is highly compatible with biological tissues. |
| US12233181B2 |
Systems and methods for monitoring disinfection of a device
Various embodiments illustrated herein disclose a method for monitoring disinfection of a device. The method includes receiving sensor data from a plurality of sensors positioned at a respective plurality of surfaces of the device. The sensor data indicates that a disinfecting agent is applied on one or more surfaces of the plurality of surfaces of the device. The method further includes determining at least one exposure characteristic based on the sensor data. The at least one exposure characteristic is associated with disinfection of the one or more surfaces of the device by the disinfecting agent. The method further includes comparing the at least one exposure characteristic to a threshold parameter associated with the at least one exposure characteristic. In response to the comparison, the method further includes generating a notification indicating that the one or more surfaces of the device are disinfected. |
| US12233178B2 |
Systems and methods of verifying effective motion of a wand assembly of an ultraviolet (UV) light sanitizing system
A system and a method include a wand assembly including a sanitizing head having an ultraviolet (UV) lamp configured to emit UV light to sanitize a surface of a component. The wand assembly further includes a first monitored member. The system also includes a second monitored member. A verification control unit is in communication with the first monitored member and the second monitored member. The verification control unit is configured to detect a speed of the wand assembly based on a comparison of the first monitored member in relation to the second monitored member. |
| US12233177B2 |
Method for external sterilization of drug delivery device
A method of externally sterilizing a drug delivery device utilizing Nitrogen Dioxide (NO2) is provided, including placing the drug delivery device in a sterilization chamber, introducing into the chamber a dose of NO2 having a concentration of between about 2 and 20 milligrams per Liter by applying a vacuum level of between about 10 and 600 Torr and holding the vacuum level for a dwell time of between about 2 and 20 minutes, repeating the step of introducing into the chamber a dose of NO2 for a number of pulses between about 1 and 24, purging the sterilization chamber of at least substantially all of the NO2, and aerating the sterilization chamber. |
| US12233176B2 |
Disinfection device
The present invention is directed to a portable, rechargeable, sanitation device that easily disinfects masks, as well as other items, by inactivating viruses and bacteria present on the mask's surface via exposure to UVC light. This sterilization device is composed of a mechanical case to storing the mask, a novel fastening device to ensure mask is properly secured in place for maximum sanitation effect, an optical component consisting of multiple UVC LEDs, a rechargeable power source, and a visual display that indicates the sanitation and lighting status of the device. This device will encourage adoption of reusable masks as opposed to one-time use, reducing costs of purchasing multiple masks as well environmental impact produced by single use waste. The device will ensure an easy solution for proper and frequent sanitation of face masks, meeting current CDC guidelines. Kits comprising the device and one or more attachment or mounting apparatus are also provided herein. |
| US12233175B2 |
Modular components, systems, and methods for disinfecting objects
Systems, apparatus, and methods are described for a disinfecting system formed of a plurality of modular units, wherein each modular unit is (1) coupleable to at least one other modular unit from the plurality of modular units and (2) includes an energy source from a plurality of energy sources. The plurality of energy sources can be configured to provide energy having an intensity capable of disinfecting a surface of the object located in a disinfecting area. |
| US12233173B2 |
Light-coupling cap sterilization system
A light-coupling cap can sterilize targets including connectors and other devices such as catheters with Luer fittings conforming to ISO 594 or ISO 80369 standards. The cap can be disposable. A light-coupling cap can reversibly attach to a connector of a target, creating a physical seal and barrier between the inside of the connector and the outside environment while at the same time transmitting light into the connector. A sterilizer can be connected to the end cap while the end cap is connected to the target. The sterilizer can include a UV light emitter that emits UV light through the end cap into the target. The light-coupling end cap sterilization system can be self-healing by measuring internal performance indicators and adjusting its operation in response to them. The light-coupling end cap sterilization system can provide to the user an indication of the amount of light dosage applied to the target. |
| US12233169B2 |
Vapor phase coating technology for pharmaceutical abuse deterrent formulations
A method of preparing an abuse deterrent pharmaceutical composition having a drug-containing core enclosed by one or more metal oxide materials is provided. The method includes the sequential steps of (a) loading the particles comprising the drug into a reactor, (b) applying a vaporous or gaseous metal precursor to the particles in the reactor, (c) performing one or more pump-purge cycles of the reactor using inert gas, (d) applying a vaporous or gaseous oxidant to the particles in the reactor, and (e) performing one or more pump-purge cycles of the reactor using inert gas. This produces an abuse deterrent pharmaceutical composition comprising a drug containing core enclosed by one or more metal oxide materials. |
| US12233167B2 |
Bio-compatible polyurethane microcapsules and process for the preparation thereof
The present invention relates to partially bio-based and bio-compatible polyurethane microcapsules. More particularly, the present invention relates to partially bio-based and bio-compatible polyurethane microcapsules for sustained release of an active ingredient. The present invention also relates to a process for the preparation of the partially bio-based and bio-compatible polyurethane microcapsules. |
| US12233166B2 |
Extended release compositions comprising pyridostigmine
Extended release pyridostigmine dosage forms, suitable for maintaining stable plasma concentrations with reduced or minimized initial burst release/dose dumping of pyridostigmine, are provided. The dosage forms include matrix tablets, gastroretentive tablets, and pellets, the latter being suitable for dosing in capsules, tablets, and sachets, as well as for sprinkling on foodstuffs. The disclosure also provides methods for improving patient compliance by administering once-a-day extended release pyridostigmine bromide dosage forms that provide a superior controlled drug release. |
| US12233165B2 |
Microsphere formulations comprising ketamine and methods for making and using the same
Extended-release, injectable microsphere formulations comprising ketamine are provided. Methods for making and using the microsphere formulations are also provided. |
| US12233162B2 |
Method for preparing liposomes
The invention relates to liposomes, methods of producing liposomes, and methods of loading cell-derived liposomes with cargo molecules. The invention extends to such liposomes per se, and to the use of these liposomes as cellular delivery systems for the delivery of biologically and therapeutically active payload molecules, such as small molecules, RNAi molecules (e.g. siRNA), bioactive proteins, genome editing tools (e.g. Cas9) and drugs into cells for treating a range of disorders. The liposomes may also be used in a range of diagnostic and theranostic applications. The invention extends to pharmaceutical compositions comprising such liposomes, including populations of extracellular vesicles (EV), exosomes and to fusion proteins. |
| US12233159B2 |
Astaxanthin nanoemulsion and manufacturing method thereof
The invention discloses an astaxanthin (AST) nanoemulsion and its manufacturing method. The manufacturing method comprising steps of: adding an AST material into a peanut oil and mixing them uniformly to obtain an AST oil; adding 0.25-1.5 (w/w) % of a surfactant into the AST oil and mixing them uniformly to obtain a mixed solution; and adding water into the mixed solution to obtain an AST emulsion precursor; and shaking the AST emulsion precursor to obtain the AST nanoemulsion. |
| US12233156B2 |
Microneedle device and method for producing the same
The present invention aims to manufacture a microneedle device capable of carrying and administering a larger amount of biologically active substance per one microneedle. One aspect of the present invention is a method of manufacturing a microneedle device comprising coating microneedles with a coating liquid, wherein the coating liquid comprises a biologically active substance and a sulfated polysaccharide. The microneedle device manufactured by such a method comprises a substrate, microneedles disposed on the substrate, and a coating formed on the microneedles, wherein the coating comprises a biologically active substance and a sulfated polysaccharide. |
| US12233154B2 |
Compositions for sensitive skin
Disclosed are compositions and methods for their use that include a combination of escin, Ruscus aculeatus root extract, ammonium glycyrrhizate. Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract. |
| US12233144B2 |
Method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors
A method for stabilizing retinoic acid precursors and a skin benefit composition with stabilized retinoic acid precursors are described. The composition has a retinoic acid precursor and a resorcinol to impede oxidation of the precursor in situ in the composition. |
| US12233140B2 |
Hyperbranched polyglycerol-coated particles and methods of making and using thereof
Core-shell particles and methods of making and using thereof are described herein. The core is formed of or contains one or more hydrophobic materials or more hydrophobic materials. The shell is formed of or contains hyperbranched polyglycerol (HPG). The HPG coating can be modified to adjust the properties of the particles. Unmodified HPG coatings impart stealth properties to the particles which resist non-specific protein absorption and increase circulation in the blood. The hydroxyl groups on the HPG coating can be chemically modified to form functional groups that react with functional groups and adhere the particles to tissue, cells, or extracellular materials, such as proteins. |
| US12233136B2 |
Myosin 15 promoters and uses thereof
The disclosure provides polynucleotides containing regions of the Myosin 15 (Myo15) promoter, as well as vectors containing the same, that can be used to promote expression of a transgene specifically in hair cells. The polynucleotides described herein may be operably linked to a transgene, such as a transgene encoding a therapeutic protein, so as to promote hair cell-specific expression of the transgene. The polynucleotides described herein may be operably linked to a therapeutic transgene and used for the treatment of subjects having or at risk of developing hearing loss or vestibular dysfunction. |
| US12233135B2 |
Therapeutic constructs for treating cancer
The present disclosure provides nucleic acid constructs for the treatment of cancer, comprising a cancer-specific promoter and one or more therapeutic genes. |
| US12233133B2 |
Preparation of solid cyclodextrin complexes for ophthalmic active pharmaceutical ingredient delivery
The present disclosure relates to ophthalmic compositions containing solid complexes of active pharmaceutical ingredient and cyclodextrin, to their method of preparation and their uses. The compositions can include an active agent drug/cyclodextrin complex substantially dissolved in an aqueous eye drop vehicle. The ophthalmic composition is generally in the form of a microsuspension including an active agent complex having a diameter of less than about 100 μm. |
| US12233131B2 |
Cationic calibrated-size gas-filled microvesicles
Technical field The invention relates to new calibrated-size gas-filled microvesicles bearing an overall positive charge, to their use and to their method of manufacturing. The gas-filled microvesicles have a geometric standard deviation (GSD) value of at least 1.25 or lower and a stabilizing envelope comprising an amphiphilic material, said amphiphilic material comprising a cationic lipid and a neutral or cationic amphiphilic polymeric compound. |
| US12233130B2 |
Covalently-modified steroid acid-peptides having enhanced stability and/or biological activity
Steroid acid-peptide conjugates covalently modified for improved stability and/or biological activity are described herein. Covalent modifications include the formation of multimeric compounds comprising at least two steroid acid-peptide monomers covalently bound to one another that behave as new chemical entities, as well as protecting one or more free thiol groups present in the steroid acid-peptide conjugates to improve their stability and/or biological activity. |
| US12233129B2 |
Methods and compositions for the treatment of cancer
Disclosed herein are compositions for treating cancer comprising a modified veratridine.In certain aspects, the modified veratridine comprises a polyglutamic acid (PLE) or polyethylene glycol/polyglutamic acid (PEG-PLE) conjugated to the 4′ hemiketal thereof. Further disclosed is a method of treating colorectal cancer in a subject comprising administering to a subject an effective amount of the disclosed compositions. |
| US12233124B2 |
Recombinant metapneumovirus f proteins and their use
Metapneumovirus (MPV) F proteins stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the MPV F proteins and/or nucleic acid molecules can be used to generate an immune response to MPV in a subject. In additional embodiments, the therapeutically effective amount of the MPV F ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing MPV infection. |
| US12233121B2 |
Methods of producing bioconjugates of E. coli O-antigen polysaccharides, compositions thereof, and methods of use thereof
Methods of producing bioconjugates of O-antigen polysaccharides covalently linked to a carrier protein using recombinant host cells are provided. The recombinant host cells used in the methods described herein encode a particular oligosaccharyl transferase enzyme depending on the O-antigen polysaccharide bioconjugate to be produced. The oligosaccharyl transferase enzymes can be PglB oligosaccharyl transferase or variants thereof. Also provided are compositions containing the bioconjugates, and methods of using the bioconjugates and compositions described herein to vaccinate a subject against extra-intestinal pathogenic E. coli. (ExPEC). |
| US12233120B2 |
Proteins and immunizing compositions containing Pasteurella proteins and methods of use
The present invention provides isolated proteins isolatable from a Pasteurella spp. such as P. multocida. Also provided by the present invention are compositions that include one or more of the proteins, and methods for making and methods for using the proteins. |
| US12233119B2 |
Composition for oral or nasal delivery of tetanus, diphtheria, and pertussis vaccine alone or in combination using neurotoxin associated proteins
The present invention describes a second-generation tetanus toxoid vaccine and a process for the preparation thereof, comprising the steps of: inducing an E. coli culture OD600=0.5 by adding 0.2 mM IPTG; growing the culture at 14-16° C. for 14 to 20 hours; suspending the culture in 25 mM phosphate buffer containing 200 mM sodium chloride; adding 1% of triton-X-100 to the phosphate buffer, and adding the buffer to the culture; sonicating the culture for a period of 3 minutes (at 5 sec on/off pulse) at 4° C. on cold beads; centrifuging the culture for 60 to 90 minutes; collecting and purifying a supernatant using Ni-NTA affinity column with an eluant; and combining the supernatant into a pool with contaminated bands and concentrating using Centriprep-30 centrifuge filters (30 kDa pores). |
| US12233118B2 |
Multivalent vaccine compositions and uses thereof
Compositions and methods are described for inducing an immune response against extra-intestinal pathogenic Escherichia coli (ExPEC) to thereby provide immune protection against diseases associated with ExPEC. In particular, compositions and methods are described for using conjugates of E. coli polysaccharide antigen O75 covalently bound to a carrier protein for the prevention of invasive ExPEC disease. |
| US12233115B2 |
Long-acting parathyroid hormone
The invention provides a long-acting parathyroid hormone peptide (PTH) that is retained in a subject's blood serum for periods of time that greatly exceed the natural hormone. The long-acting PTH is conjugated to at the carbon 3 position of a non-hormonal vitamin D via a scaffold of discreet length that facilitates its purification, detection, solubility, and efficacy at the PTH receptor (PTHR). The PTH may be conjugated to the non-hormonal vitamin D via a 36 mer poly(ethylene glycol) moiety (PTH-PEG36-VitD). The invention also provides optimized manufacturing methods and formulations. The PTH-PEG36-VitD has a vastly-improved serum half-life and bioavailability when compared to a non-conjugated PTH peptide. PTH-PEG36-VitD also significantly increases serum calcium, reduces urinary calcium, and reduces serum phosphate. |
| US12233114B2 |
Method for treating diabetes
The present invention relates to insulin degludec for use in medicine. |
| US12233113B2 |
Pharmaceutical composition comprising recombinant hGH for the treatment of growth hormone deficiency
Provided are a method for administering a recombinant human growth hormone GX-H9 for treating growth hormone deficiency and a pharmaceutical composition containing a recombinant human growth hormone GX-H9 and a pharmaceutically acceptable carrier. The method includes administering recombinant human growth hormone GX-H9 once a week with a dosage of 0.1 to 0.3 mg per weight kg of a patient or twice-monthly with a dosage of 0.1 to 0.4 mg per weight kg of the patient. |
| US12233111B2 |
Compositions comprising pharmaceutically acceptable salts of glucagon-like peptide-1 analogs and uses thereof
Provided herein are compounds having the structure of Formula Ia, wherein the compounds comprise a therapeutic agent having the sequence of SEQ ID NO: 35, and the compounds have an anion:cation molar ratio of from about 1:1 to about 1:7, and methods of using thereof for the treatment of metabolic diseases or disorders, including type 1 diabetes, type 2 diabetes, obesity, overweight, and nonalcoholic steatohepatitis, and for reducing weight in a subject in need thereof. |
| US12233104B2 |
Combination of an IL-2RBETA-selective agonist and a long-acting IL-15 agonist
In one or more embodiments of the invention, a method is provided, the method comprising the steps of administering to a cancer patient: (a) an IL-2Rβ-activating amount of a long-acting, IL-2Rβ-selective agonist; and (b) an IL-15R-activating amount of a long-acting, IL-15 moiety. In one or more embodiments of the invention, a composition is provided, the composition comprising: an IL-2Rβ-activating amount of a long-acting, IL-2Rβ-selective agonist; and an IL-15R-activating amount of a long-acting, IL-15 moiety. In one or more embodiments of the invention, a kit is provided, the kit comprising: an IL-2Rβ-activating amount of a long-acting, IL-2Rβ-selective agonist; an IL-15R-activating amount of a long-acting, IL-15 moiety; and instructions for use of the IL-2Rβ-selective agonist and the long-acting, IL-15 moiety. |
| US12233102B2 |
Alvoecore a respiratory system protection product and immune system booster
The present invention is a respiratory system protection product and a method for creating said product. The product is created by separating an aloe vera gel from a quantity of aloe vera leaves. The aloe vera gel is added to a heating vessel. A first solution is prepared and added to cover the aloe vera gel. The heating vessel is covered, heated, and stirred until boiling, then removed from heat. After cooling to room temperature an oil component is added. The mixture is blended and amalgamated, then filtered to remove solid materials. In some embodiments, baking soda may be added to further induce chemical reactions amongst the ingredients. |
| US12233101B2 |
Compositions and methods useful in treatment of lower urinary tract symptoms, benign prostatic hyperplasia, erectile dysfunction, and other diseases or symptoms
The invention relates to therapeutic compositions, solid oral dosage forms, and methods for treating, preventing, or alleviating lower urinary tract symptoms (LUTS), benign prostatic hyperplasia (BPH), erectile dysfunction (ED), urinary incontinence, bladder obstruction, overactive bladder (OAB), underactive bladder, interstitial cystitis, prostatitis, bladder and prostate inflammation, prostate fibrosis or pelvic pain. The therapeutic compositions can comprise cranberry powder enriched in cranberry seeds or cranberry seed meal. |
| US12233100B1 |
Composition for improving respiratory health of companion animals
A composition for improving respiratory health of companion animals, includes butyric acid as a short-chain fatty acid, propionic acid as a short-chain fatty acid, acetic acid as a short-chain fatty acid, red ginseng extract powder, Siberian gooseberry extract powder, omega-3 fatty acid, glutathione powder, chlorella powder, spirulina powder, propolis powder, plantago seed (psyllium) husk powder, zinc powder and CTF-901 as active ingredients, thereby inhibiting bronchial thickening in airway smooth muscle cells through edible feeding thus to contribute to enhancement of respiratory health. |
| US12233099B2 |
Composition for promoting myogenesis, containing processed ginseng extract
The present invention relates to a composition for promoting myogenesis, containing, as an active ingredient, a processed ginseng extract in which a trace amount of a ginsenoside ingredient is increased. It has been ascertained that the processed ginseng extract promotes the differentiation of myoblasts into muscle and inhibits muscle atrophy caused by myostatin, which is a myogenesis inhibitory factor, and thus it is expected that a composition for preventing or treating muscle disorder-related diseases, having excellent effects, can be developed. |
| US12233097B2 |
Compositions and methods for promoting a healthy microbial flora in a mammal
The disclosure provides compositions and dosage forms for promoting healthy microbial flora in a mammal, for example, a human. The disclosure further provides compositions and dosage forms for disrupting biofilm or preventing formation of biofilm containing pathogenic bacteria and/or pathogenic fungi in a particular region of a subject. The dosage forms contain (i) an isolated non-pathogenic fungal strain that is viable in the region of the subject, (ii) an isolated non-pathogenic bacterial strain that is viable in the region of the subject, and optionally (iii) an enzyme capable of disrupting the biofilm. The present disclosure also provides methods of disrupting a biofilm or preventing formation of a biofilm with such a composition or dosage form, methods of identifying a subject suitable for treatment with such a composition or dosage form, and methods of improving nutrient absorption using such a composition or dosage form. |
| US12233095B2 |
Methods and compositions for treatment of microbiome associated disorders
Disclosed herein are methods and compositions for treatment of a microbiome associated disorder. Further, disclosed herein are methods and compositions for modulating short chain fatty acid production in a subject. |
| US12233094B2 |
Interaction of fibroblasts and immune cells for activation and uses thereof
The present disclosure is directed to systems, methods, and compositions for functional interaction of fibroblasts with one or more types of immune cells such that the interaction results in modification to the fibroblasts, the one or more types of immune cells, or both. In some embodiments, one or more certain agents are also utilized during the interaction or in lieu of one of the types of cells. In specific embodiments, cells to be used in cellular transplantation therapy are modified to have reduced immunogenicity. |
| US12233092B2 |
MSC-NTF specific exosomes and use thereof
Provided herein are highly-characterized isolated exosomes, methods to produce such exosomes, and methods for the use of such exosomes in treating diseases such as neurodegenerative diseases. |
| US12233091B2 |
Vaccine compositions and methods
The present invention relates to pharmaceutical vaccine compositions comprising at least one vaccine antigen together with living immune cells. These immune cells include at least a portion of activated T-cells and act as an adjuvant. Methods for using these pharmaceutical compositions to prevent or treat diseases, such as cancer, infectious diseases and autoimmune disease are also included. |
| US12233089B2 |
Foods to promote better health and/or to maintain homeostasis and method of production thereof
Engineered food to promote health and maintain homeostasis in a subject and methods of producing the food. |
| US12233086B2 |
Biomarkers for neurogenerative disease
Described herein are methods of monitoring and treating a subject with ALS based on biomarkers. |
| US12233085B2 |
Application of hyaluronic acid in preparing medicines for preventing or treating ferroptosis-related diseases
An application of hyaluronic acid in preparing medicines for preventing or treating ferroptosis-related diseases is provided, and an application of hyaluronic acid or salts of hyaluronic acid or derivatives of hyaluronic acid in preparing medicines for inhibiting ferroptosis is also provided. According to the present application, the anti-ferroptosis function of hyaluronic acid is disclosed. The hyaluronic acid is the first natural extracellular matrix material with anti-ferroptosis function found at present. The hyaluronic acid is one of the components of natural extracellular matrix and exists in large quantities in human body and is also a widely used material in clinic. |
| US12233081B2 |
Hygromycin a compounds and methods of treating spirochete diseases
This invention provides, among other things, compounds useful for treating spirochete diseases such as Lyme disease, as well as pharmaceutical formulations and/or environmental baits containing such compounds. |
| US12233080B2 |
Lipotechoic acid for immune modulation
Provided herein are compositions comprising lipotechoic acid (LTA) and methods of use thereof for immune modulation. In particular, compositions comprising S. epidermidis lipotechoic Acid (SELTA) are provided, as well as method of use thereof for the treatment of immune—(e.g., autoimmune) and inflammation-related conditions and diseases (e.g., chronic pelvic pain syndrome (CPPS), arthritis, etc.). |
| US12233078B2 |
Method and kit for analysis of drug resistance of tumor cells
The present invention discloses a method for analysis of drug resistance of tumor cells. The method includes the steps of: (a) providing silicon dioxide nanoparticles, polystyrene-co-polyacrylic acid nanoparticles or metal-organic framework nanoparticles; (b) co-incubating the silicon dioxide nanoparticles, the polystyrene-co-polyacrylic acid nanoparticles or the metal-organic framework nanoparticles with the tumor cells; and (c) detecting endocytosis of the silicon dioxide nanoparticles, the polystyrene-co-polyacrylic acid nanoparticles or the metal-organic framework nanoparticles by the tumor cells. The analysis method of the present invention can analytically identify drug-resistant tumor cells in a clear, intuitive and efficient way. The provided nanoparticles feature simple synthesis processes that take short periods of time, and after they are co-incubated with the tumor cells, a flow cytometer is used for detection. Based on a result of the detection, a degree of drug-resistance of the tumor cells and a proportion of drug-resistant cells therein are determined, making the method simple and efficient. |
| US12233076B2 |
Stable liquid formulations of cyclophosphamide and processes to prepare the same
The present invention relates to stable liquid pharmaceutical formulations of cyclophosphamide comprising cyclophosphamide and at least one pharmaceutically acceptable excipient wherein moisture content of the liquid formulation is less than about 2.0% by weight. The invention further relates to stable liquid formulations of cyclophosphamide prepared by a process comprising a step of reducing the moisture content from cyclophosphamide or liquid compositions of cyclophosphamide or both. The invention further relate to method of using such stable liquid formulations of cyclophosphamide for parenteral administration either as ready-to-use or ready-to-dilute for treating various cancer disorders. |
| US12233073B2 |
Skin care formulations and skin cancer treatment
An example technique for treating a skin cancer condition includes administering a therapeutically effective amount of a p53-related protein kinase (PRPK) inhibitor to a patient having skin cancer or having a high risk of developing skin cancer. An example composition includes a therapeutically effective amount of a PRPK inhibitor for treating a skin cancer condition. An example composition includes a pharmaceutically effective amount of at least one anti-solar ultraviolet (anti-sUV) combination for preventing a skin cancer condition. The at least one anti-sUV combination is chosen from the combinations: avobenzone and octinoxate; octocrylene and zinc oxide; avobenzone, octocrylene, and titanium dioxide; or avobenzone, octocrylene, and zinc oxide. |
| US12233072B2 |
Compositions comprising bisfluoroalkyl-1,4-benzodiazepinone compounds for treating Adenoid Cystic Carcinoma
The present invention provides methods of treating or suppressing Adenoid Cystic Carcinoma (ACC) or inhibiting ACC tumor growth in subjects by administering compositions comprising bisfluoroalkyl-1,4-benzodiazepinone compounds, including compounds of Formula (III) or prodrugs thereof. |
| US12233070B2 |
Methods for treating benzodiazepine misuse/use disorder
Disclosed are compositions and methods for treating benzodiazepine misuse and/or use disorder. A method of treating benzodiazepine misuse and/or use disorder includes administering to a subject in need thereof of an effective amount of a compound provides both partial modulator and antagonist effects at GABAA receptors. |
| US12233066B2 |
Combinations of inhibitors of influenza virus replication
Provided herein are combinations of compounds that can inhibit the replication of influenza viruses, reduce the amount of influenza viruses, and/or treat influenza. |
| US12233065B2 |
Inhibitors of RNA helicase DHX9 and uses thereof
Provided are compounds of the Formula (IVB): or pharmaceutically acceptable salts thereof, which are useful for the inhibition of DHX9 and in the treatment of a variety of DHX9 mediated conditions or diseases, such as cancer. |
| US12233059B2 |
Effective treatment of depression in patients having impaired learning and/or memory or certain EEG characteristics with a benzylpiperazine-aminopyridine agent
This invention relates to the use of (4-benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone (NSI-189) or a pharmaceutically acceptable salt thereof in the treatment of a psychiatric condition in which depressive symptoms are prominent, including major depressive disorder (MDD), bipolar disorder, post-traumatic stress disorder, substance use disorder, and depression-related aspects of schizophrenia (e.g. negative symptoms) in select patients who exhibit impaired learning and/or memory. The invention also relates to the use of NSI-189 or a pharmaceutically acceptable salt thereof in the treatment of a psychiatric condition in which depressive symptoms are prominent, including major depressive disorder (MDD), in select patients who exhibit impaired learning and/or memory or certain EEG characteristics. |
| US12233058B2 |
Methods of treating non-obstructive hypertrophic cardiomyopathy using modified forms of trimetazidine
The invention provides methods of treatment of non-obstructive hypertrophic cardiomyopathy using modified forms of trimetazidine, such as CV-8972 and CV-8814. |
| US12233057B2 |
Small molecules for inhibiting chemokine activity and/or cancer cells growth
Compounds capable of, or usable in, inducing death of cancer cells and/or modulating a biological activity of a chemokine e.g., cell migration, and/or treating diseases and disorders associated with a biological activity of a chemokine and/or cell migration, and/or inhibiting a kinase and/or in treating a disease or disorder associated with an activity of a kinase, such as cancer and inflammatory diseases and disorders, are provided herein. The compounds are collectively represented by Formulae Ia or Ib: wherein A, B D, E, G and R1-R5 are as defined in the specification. |
| US12233056B2 |
Lysyl oxidase inhibitors for treating myeloid malignancies
Lysyl oxidase (LOX) inhibitors, lysyl oxidase-like (LOXL) inhibitors, or pharmaceutically acceptable salts thereof and methods for the treatment of myeloid malignancies, comprising administering a therapeutically effective amount of those inhibitors alone or optionally in combination with a second therapeutic agent. |
| US12233055B2 |
Topical Montelukast formulations
The present disclosure provides for topical emulsion comprising about 0.5% to about 10% Montelukast or pharmaceutically acceptable salt thereof; and about 0.4% to about 4% carbomer; wherein particles comprising the Montelukast in the emulsion have D90 of less than about 50 μm, wherein the Montelukast or pharmaceutically acceptable salt thereof is homogeneously dispersed in the emulsion, and wherein the emulsion has a pH of about 3.0 to about 6.5. The present disclosure also provides a topical gel comprising (a) about 0.5% to about 10% Montelukast or pharmaceutically acceptable salt thereof; (b) about 0.2% to about 8% cellulose polymer; and (c) about 80% to about 95% amphiphilic compound; wherein the gel comprises less than 4% water. |
| US12233053B2 |
Adenosine A3 receptor antagonists for treating aging skin and wounds
The invention provides a method of improving the appearance of aging skin by administering locally to an area of the aging skin of a subject a cosmetic or dermatological composition that includes an effective amount of an adensoine A3 receptor antagonist and a dermatologically acceptable carrier, thereby improving the appearance of the area of the aging skin. |
| US12233052B2 |
Tetrahydro-pyrido[3,4-b]indole estrogen receptor modulators and uses thereof
Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors. |
| US12233046B2 |
Psychoactive medicines and their use for treating psychiatric and neurological conditions and disorders
The invention relates to psychoactive medicines including 2C-B, methylone, MBDB, their respective metabolites, isomers, enantiomers, polymorphs, and analogues (2C-series and cathinones); their preparation, formulations, intermediates, routes of administration, dosing and schedule for medical uses for psychiatric and neurological conditions and disorders. |
| US12233042B2 |
Treatment of cutaneous disorders
Methods of treating one or more skin lesions using cantharidin as well as associated compositions, treatment regimens, kits, devices, and systems are provided. A method of treating a subject having one or more skin lesions may involve administering a composition comprising cantharidin to one or more skin lesions. The method may allow for the efficacious treatment of the skin lesion(s) with minimal or no adverse side effects (e.g., severe adverse side effects, permanent damage of the dermal tissue, scarring, excessive blistering of skin surrounding the lesion, elevated plasma cantharidin concentration, systemic exposure to cantharidin). The efficacy and/or safety of the treatment may be due, to certain features of the composition and/or prolonged exposure of the skin lesion(s) to cantharidin. The methods described herein may be used for a wide variety of cutaneous disorders, including skin disorders that primarily affect the epidermis of skin. |
| US12233040B2 |
Combustible and edible composition of medium-chain triglycerides and silicic acid
The present invention relates to a combustible and edible composition comprising medium-chain triacylglycerols and silica, wherein the composition is in one embodiment a solid shaped body. The invention further relates to the use of a composition or of a solid shaped body as an item of equipment for outdoor activities, camping, sports activities, and/or in a diet. |
| US12233037B2 |
Method for producing a polyphenolic composition from barley malt
Method for the production of a polyphenolic composition from barley malt, including the fundamental steps of: grinding of the malt grains and splitting into two portions, 20% and 80%; mixing each of the two portions with water to obtain an A mixture and a B mixture, the A mixture being prepared with the 20% portion to obtain a mixture of the malt in water at a final concentration between 9.5% and 20%, the B mixture being prepared with the 80% portion to obtain a mixture of the malt in water at a final concentration between 33% and 60%; thermal cycle; separation of the liquid component from the solid component; boiling of the liquid component and the addition of hops; rapid cooling of the wort; storage; in which said thermal cycle consists of a first phase and a second phase, in which the first phase applies to the 20% portion (Mixture A) and the second phase during which Mixture B is added to Mixture A. The relative polyphenolic composition obtained according to this method is characterized by the fact that it can be in liquid, powder, dry, and lyophilized form, its use and relative beverage or beer according to the present method not obtained with fermentation methods. |
| US12233035B2 |
Method of treating cardiovascular events using colchicine concurrently with an antiplatelet agent and statin
A method for reducing a composite endpoint risk of myocardial infarction (MI), stroke, coronary revascularization, unstable angina requiring hospitalization, cardiac arrest, and cardiovascular death in a subject including administering, orally once per day to the subject, a composition comprising about 0.5 total mg of (i) colchicine, (ii) a pharmaceutically acceptable salt of (i), or any combination of (i) and (ii), wherein the patient has at least one history of diabetes, a past myocardial infarction, an unstable angina, a coronary bypass surgery, and a coronary angioplasty; wherein the patient is also administered a daily dose of statin therapy; and wherein the composite endpoint risk in the subject is reduced relative to a dosing regimen where the patient receives standard secondary prevention therapy of a statin. |
| US12233034B2 |
Formulations for epidermal repair
The present disclosure is directed to dermatological formulations and their use for treating a variety of dermatological diseases and disorders, and for repairing and restoring a disrupted epidermal barrier, inhibiting inflammation, restoring a proper environment for maintaining a balanced symbiotic microbiome, and inhibiting the growth of pathogenic microorganisms in the epidermis—the outer layer of mammalian skin. |
| US12233032B2 |
Compositions for management of polycystic ovary syndrome
The invention discloses compositions comprising bisdemethoxycurcumin and methods for managing polycystic ovary syndrome (PCOS) and its associated conditions which include hormonal imbalance, obesity, hypothyroidism, hyperandrogenism, oxidative stress, inflammation, gut dysbiosis, hypercholesterolemia, cardiovascular complications, hyperglycemia and insulin resistance. The invention also discloses the potential of a curcuminoid composition comprising 20-80% w/w bisdemethoxycurcumin, 10-35% w/w demethoxycurcumin and 10-50% w/w curcumin for use in the therapeutic management of PCOS. |
| US12233031B2 |
Closing station, capsule filling machine and method thereof
The present invention discloses a closing station for a capsule filling machine comprising a bottom and a top closing unit configured to displace towards each other, such that bottom pins associated with said bottom closing unit urge into through holes of a body holder (B) to contact closed ends of each filled capsule body sections and sliding them into said open ends of each capsule cap sections, such that each capsule is partially closed against an exerting pre-compressive force of the top pins and is completely closed when force against biasing means of said top pins is exerted for providing telescoping closing of the cap and body sections of each capsule. |
| US12233023B2 |
Myofascial release apparatus
A myofascial release apparatus can include a head member and a shaft configured to couple to the head member and to releasably mount the head member to a weightlifting rack. This can be accomplished, for example, by threading the shaft of the apparatus through apertures on a support member of the weightlifting rack and placing a securing member or securing loop on the shaft to prevent the shaft from retreating through the support member during use. The apparatus can be included in a kit having one or more of the following additional components: a washer, a magnet, collars, two or more additional head members, or a handle. The head members can be any suitable shape, including a blunt nub head, a precision nub head, and/or a broad nub head. |
| US12233014B2 |
Modular patient lift system
A modular patient lift system includes a ceiling grid, a plurality of rails, a gantry configured to traverse the ceiling grid via the plurality of rails, and a patient lift coupled to the gantry and configured to traverse the ceiling grid with the gantry. The modular patient lift system further includes one or more sensors provided on at least one of the plurality of rails, the gantry, and the patient lift, the one or more sensors configured to collect at least one of environmental data and position data. |
| US12233011B2 |
Radiology holding unit for a radiology device
A radiology holding device (1) for a radiology apparatus (50) such as an X-ray apparatus (51), a magnetic resonance tomography apparatus (52), a computerized tomography apparatus (53) or a radiotherapy apparatus (54), comprising an attachment device (2) and pivotally accommodated thereon, a supporting arm (3) having at least one axle component (4) pivotally accommodated on the attachment device and a supporting component (5). Furthermore, a locking device (6) is provided for locking the supporting arm (3) in at least one locking position (7). An actuating mechanism (8) serves to actuate the locking device. A holding device (9) attached to the supporting arm (3) provides a patient with a holding means. The actuating mechanism (8) comprises a transfer component (11) passing through a hollow section (10) of the axle component (4). |
| US12233010B2 |
Patient support apparatus with ramp transition detection
A patient support apparatus for transporting a patient over a floor surface is described herein. The patient support apparatus includes a drive system with a drive member, a user interface for receiving user commands from a user to operate the drive system, and a control system for operating the drive system. The control system includes a memory device configured to store a plurality of transition profiles and a controller configured to sense a plurality of positions of the drive member relative to the support structure, calculate a distance traveled by the patient support apparatus over the floor surface, compare the plurality of positions of the drive member and the distance traveled by the patient support apparatus with the transition profiles, and determine that the patient support apparatus is traveling on an inclined floor surface. |
| US12233009B2 |
Controlling device for adjustable bed foundation
A sleep system comprises at least one mattress including a first sleep area for a first occupant, the first sleep area including a first section for a portion of a body of the first occupant, and a second sleep area adjacent to the first sleep area for a second occupant, the second sleep area including a second section for a portion of a body of the second occupant, an articulation system for articulating the first section and the second section, a first user controller configured to communicate with the articulation system in order to control articulation of the first section, and a second user controller configured to communicate with the articulation system in order to control articulation of the second section, wherein the first user controller is further configured to communicate with the articulation system in order to move the second section into a predetermined position. |
| US12233005B2 |
Systems and methods for aligning an eye with a patient interface of an ophthalmic laser device
In certain embodiments, a system for aligning an eye with a patient interface of a laser device includes a camera, a display screen, and a computer. The camera records images of the eye through the patient interface of the laser device. A liquid is disposed between and is in contact with the patient interface and the outer surface of the eye. The images include an outline of the liquid. The display screen displays the images of the eye. The computer aligns the eye with the patient interface by: identifying the outline of the liquid in an image received from the camera; determining a misalignment of the eye according to the outline; and instructing the display screen to display a description of the misalignment. |
| US12233004B2 |
Ocular implant with stiffness qualities, methods of implantation and system
Described herein are devices and methods for treating eye conditions. Described is an ocular implant including an elongate member having an internal lumen forming a flow pathway, at least one inflow port communicating with the flow pathway, and at least one outflow port communicating with the flow pathway. The elongate member is adapted to be positioned in the eye such that at least one inflow port communicates with the anterior chamber, at least one outflow port communicates with the suprachoroidal space to provide a fluid pathway between the anterior chamber and the suprachoroidal space when the elongate member is implanted in the eye. The elongate member has a wall material imparting a stiffness to the elongate member. The stiffness is selected such that after implantation the elongate member deforms eye tissue surrounding the suprachoroidal space forming a tented volume. |
| US12233001B2 |
Enclosure ventilation filter
A filter assembly for an enclosure, particularly for an ostomy bag, is described having an enclosure side, a first layer which is gas permeable, and an adsorbent layer comprising adsorbent particles dispersed in a fine fiber web. The enclosure side of the filter assembly includes an adhesive zone in which adhesive is present having an outer adhesive perimeter and a weld area surrounding at least a portion of the adhesive zone, where the filter assembly is heat-sealable to the enclosure at the weld area. A method of assembly is also described. |
| US12232996B2 |
Patient stabilization and securing device for robotic and laparoscopic surgeries in trendelenburg position
The present application is directed to a method and system for restraining a patient before, during, or after surgery that increases efficiency of the surgical setup process and minimizes risk of musculoskeletal damage to the patient, particularly in surgeries requiring a patient to be in a Trendelenburg position (e.g., robotic or laparoscopic surgeries). One or more restraints can be worn by a patient prior to surgery', and may function to redistribute the patient's weight across the patient's torso to reduce strain on the patient's shoulders and back. The restraint(s) can be attached to a surgical table by way of an attachment mechanism coupled to the restraint(s) and the table. The attachment mechanism can secure the patient to the table by way of one or more straps, clips, and/or other intermediates. Optionally, the restraint(s) can fulfill other surgical needs, such as heat regulation and vascular compression. |
| US12232987B2 |
Stent
The invention relates to a medical device and a method of using it. The device is a stent which can be percutaneously deliverable with (or on) an endovascular catheter or via other surgical or other techniques and then expanded. The stent is configured to have a central portion defined by “open” cells and at least two end portions, defined by “closed” cells, spaced apart and directly connected to the distal and proximal ends of the central portion of the stent. The stent may also optionally have a covering or a lattice with openings. |
| US12232983B2 |
Vertebral implants and attachment assemblies
A prosthetic implant for engagement between first and second vertebrae. The implant includes a first plate configured for attachment to the first vertebrae and defining a first interbody connection member and a second plate configured for attachment to the second vertebrae and defining a second interbody connection member. An interbody component includes a body with a first end defining a first plate connection member configured for connection to the first interbody connection member and a second end defining a second plate connection member configured for connection to the second interbody connection member. A method of inserting the implant is also provided. |
| US12232975B2 |
Lockable spinal implant
A spinal implant which is configured to be deployed between adjacent vertebral bodies. The implant has at least one extendable support element with a retracted configuration to facilitate deployment of the implant and an extended configuration so as to expand the implant and effectively distract the disc space, stabilize the motion segments and eliminate pathologic spine motion. The implant has a minimal dimension in its unexpanded state that is smaller than the dimensions of the neuroforamen through which it typically passes to be deployed within the intervertebral space. The implant is provided with a locking system having a plurality of linked locking elements that work in unison to lock the implant in an extended configuration. Bone engaging anchors also may be provided to ensure secure positioning. |
| US12232973B2 |
Intervertebral internal screw guide and fixation apparatus including screw lock
A bi-directional fixating transvertebral (BDFT) screw/cage apparatus including an intervertebral cage for maintaining disc height, and a method of inserting the same is provided. The intervertebral cage includes a first internal screw guide and a second internal screw guide, a first screw member and a second screw member, and a central screw locking lever coupled to the intervertebral cage, wherein the central screw locking lever prevents the first screw member and the second screw from pulling-out of the first internal screw guide and the second internal screw guide. The central screw locking lever includes a rotatable handle and stem portion, or a screw locking horizontal bracket. A pliers device for inserting and removing the bi-directional fixating transvertebral (BDFT) screw/cage apparatus, a posterior cervical and lumbar facet joint staple, and a staple gun for a posterior cervical and lumbar facet joint staple also are provided. |
| US12232968B2 |
Knee joint device and method
A medical device for creating an artificial knee joint or an artificial cruciate ligament in a mammal patient, the medical device comprising a transversal member adapted to be placed through at least three layers of cortical bone of the distal portion of the femoral bone, out of totally four cortical layers along a prolongation of the transversal member. The transversal member is adapted to be involved in the artificial knee joint or the artificial cruciate ligament, wherein the transversal member comprises at least one fixation portion adapted to be involved in fixation of the transversal member to at least one of the at least four layers of femoral cortical bone. |
| US12232965B2 |
Patient specific graft cage for craniomaxillofacial repair
A method of forming a patient-specific-bone-graft cage based on a patient-specific bone graft cage computer model that is based on a contour of a surface of the bone defining a void, and/or a patient-specific-bone-graft cage that includes a plurality of apertures, that terminate at a location between a front surface and a back surface of the patient-specific-bone-graft cage, for receipt of bone graft material. The patient-specific-bone-graft cage can construct an essential portion (including complex thin anatomical structures) of or substantially the entirety of the mid-face region (e.g., to fill a void in a damaged orbital region), which enables an improved structure reproduction and simplification for the surgeon. For example, the patient-specific-bone-graft cage may be formed based on the contour of the periphery defining the void in the damaged region, and require less modification by a surgeon compared to graft cages formed only by mirroring techniques or normalized models. |
| US12232962B2 |
Methods and devices to reduce the risk of infection
Articles for reducing the risk of infection, bearing, or containing an antimicrobial composition containing a solid-phase peroxyxcarboxylic acid metal salt are provided. Methods of reducing the risk of infection using the antimicrobial composition are also provided. |
| US12232954B2 |
Artificial valve
The present invention relates to a method of placing an artificial valve in a blood vessel of a mammal patient. The method involves placing the artificial valve into the blood vessel. The artificial valve comprises a casing and a closing mechanism, with at least part of said closing mechanism being a first moving part which is adapted to make movements relative to the casing to assume an open position and a closed position for opening and closing, respectively, a blood flow through a blood vessel of the body, as well as positions between said open and closed positions. |
| US12232952B2 |
Ophthalmic implants with extended depth of field and enhanced distance visual acuity
A lens configured for implantation into an eye of a human can include an optic including transparent material. The optic can have an anterior surface and a posterior surface. The anterior surface can be convex and the posterior surface can be concave such that the optic is meniscus shaped. Each of the convex anterior surface and the concave posterior surface can have a surface vertex. The optic can have an optical axis through the surface vertices and a thickness along the optical axis that is between about 100-700 micrometers. The lens can also include haptic portions disposed about the optic to affix the optic in the eye when implanted therein. The anterior and posterior surfaces can include aspheric surfaces. |
| US12232951B2 |
Optical material and method for modifying the refractive index
An optical device comprising an optical hydrogel with select regions that have been irradiated with laser light having a pulse energy from 0.01 nJ to 50 nJ and a wavelength from 600 nm to 900 nm. The irradiated regions are characterized by a positive change in refractive index of from 0.01 to 0.06, and exhibit little or no scattering loss. The optical hydrogel is prepared with a hydrophilic monomer. |