最新美国发明专利第2023-01-24期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

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US11560652B2	Knitted component having at least one thermoplastic polymer element A knitted component may include a molded thermoplastic polymer element surrounded by a knit element, where the knit element includes a first layer forming a first side and a second layer forming a second side facing opposite the first side, the first layer and the second layer being coextensive and secured via interlooped knit loops that form at least a portion of the molded thermoplastic polymer element. The first side may include the molded thermoplastic polymer element, where the second layer is coextensive with the thermoplastic polymer element, and where the second side faces opposite the first side.
US11560650B2	Fiber structure and a composite material part incorporating such a structure A method of fabricating a fiber structure by multilayer three-dimensional weaving between a plurality of weft yarns and of warp yarns, the fiber structure having at least first and second portions that are adjacent in the warp direction, the first portion presenting, in a direction perpendicular to the warp and weft directions, a thickness greater than the thickness of the second portion, includes making the first portion using a step of three-dimensionally weaving warp and weft layers in which a fiber fabric is formed in the form of a Mock-Leno weave grid in a core of the first portion together with skins at a surface of the first portion, a weave of the skins being modified locally so as to deflect certain warp yarns from said skins and weave them with the fiber fabric in the form of the Mock-Leno weave grid.
US11560644B2	Supramolecular tessellation of rigid triangular macrocycles Disclosed herein are crystalline compositions comprising tessellated rigid triangular macrocycles in a two-dimensional plane and methods of making the same.
US11560641B2	Surface-treated aluminum material having excellent adhesiveness to resins, method for manufacturing the same, and surface-treated aluminum material-resin bonded body The present disclosure provides a surface-treated aluminum material having excellent adhesiveness to resins, on the surface of which an oxide film is formed, the oxide film comprising a surface-side porous aluminum oxide film having a thickness of 20 to 500 nm and a base-side barrier aluminum oxide film having a thickness of 3 to 30 nm, wherein small pores each having a diameter of 5 to 30 nm are formed on the porous aluminum oxide film, and the length of cracks formed in a boundary between the porous aluminum oxide film and the barrier aluminum oxide film is not more than 50% of the length of the boundary, a method for manufacturing the surface-treated aluminum material, and a surface-treated aluminum material-resin bonded body, comprising the surface-treated aluminum material and a resin that covers the surface of the oxide film formed thereon.
US11560640B2	Filling plating system and filling plating method The purpose of the present invention is to provide a filling plating system and a filling plating method capable of filling plating sufficiently even if the plating is interrupted between electrolytic plating cells. A filling plating system for forming filling plating in a via hole and/or a through hole of a work to be plated, comprising: a plurality of electrolytic plating cells; and an additive adhesion region arranged between each of the plurality of electrolytic plating cells, wherein solution containing one or more kinds of additive selected from at least a leveler comprising nitrogen-containing organic compound, a brightener comprising sulfur-containing organic compound, and a carrier comprising polyether compound, is directly adhered to the work to be plated at the additive adhesion region.
US11560637B2	Electrolytic reduction device and electrolytic reduction method To improve the efficiency of a reduction reaction. A power source applies a voltage to an oxidation electrode immersed in an aqueous solution in an oxidation tank and a reduction electrode immersed in an aqueous solution in a reduction tank, the voltage having a voltage value that changes with a predetermined cycle to be a voltage value at which ions can be desorbed from a surface of the oxidation electrode and a surface of the reduction electrode during one cycle of the voltage change. The frequency of the voltage is set within a range of 10 Hz to 1 kHz.
US11560636B2	Low temperature electrolytes for solid oxide cells having high ionic conductivity Methods for forming a metal oxide electrolyte improve ionic conductivity. Some of those methods involve applying a first metal compound to a substrate, converting that metal compound to a metal oxide, applying a different metal compound to the metal oxide, and converting the different metal compound to form a second metal oxide. That substrate may be in nanobar form that conforms to an orientation imparted by a magnetic field or an electric field applied before or during the converting. Electrolytes so formed can be used in solid oxide fuel cells, electrolyzers, and sensors, among other applications.
US11560629B2	Methods of preparing articles by electrodeposition and additive manufacturing processes Articles prepared by additive manufacturing of preforms that are coated by electrodeposition of nanolaminate materials, and methods of their production are described.
US11560624B2	Precursor delivery system A precursor delivery system is described herein. Some embodiments provide a precursor delivery system capable of providing a uniform gas flow comprising precursor into a processing chamber for atomic layer deposition processes. Some embodiments of the precursor delivery system comprise a reservoir with an inlet line, an outlet line and an outlet valve. Further embodiments comprise a precursor source, an inlet valve, a heater, a processing chamber and a controller. Additional embodiments relate to methods for using a precursor delivery system.
US11560620B2	Gold sputtering target and method for producing the same A gold sputtering target has a gold purity of 99.999% or more. In such a gold sputtering target, an average value of Vickers hardness is 20 or more and less than 40, an average crystal grain size is 15 μm or more and 200 μm or less, and a {110} plane of gold is preferentially oriented to a surface to be sputtered of the gold sputtering target.
US11560619B2	Laminate and method of producing the same, and gas barrier film and method of producing the same A laminate that improves barrier properties of an atomic layer deposition film in spite of use of a substrate made of a polymer material, and provides a gas barrier film and a method of producing the same. The laminate includes: a substrate made a polymer material; an undercoat layer disposed on at least part of a surface of the substrate and made up of an inorganic material containing Ta; and an atomic layer deposition film disposed so as to cover a surface of the undercoat layer.
US11560618B2	Al—Cr-based ceramic coatings with increased thermal stability The present invention relates to a method for producing a multilayer film comprising aluminum, chromium, oxygen and nitrogen, in a vacuum coating chamber, the multilayer film comprising layers of type A and layers of type B deposited alternate one of each other, wherein during deposition of the multilayer film at least one target comprising aluminum and chromium is operated as cathode by means of a PVD technique and used in this manner as material source for supplying aluminum and chromium, and an oxygen gas flow and a nitrogen gas flow are introduced as reactive gases in the vacuum chamber for reacting with aluminum and chromium, thereby supplying oxygen and nitrogen for forming the multilayer film, characterized in that: —The A layers are deposited as oxynitride layers of Al—Cr—O—N by using nitrogen and oxygen as reactive gas at the same time, —The B layers are deposited as nitride layers of Al—Cr—N by reducing the oxygen gas flow and by increasing the nitrogen gas flow in order to use only nitrogen as reactive gas for the formation of the Al—Cr—N layer, and wherein the relation between oxygen content and nitrogen content in the multilayer film correspond to a ratio in atomic percentage having a value between and including 1.8 and 4.
US11560614B2	High-strength galvanized steel sheet, high strength member, and method for manufacturing the same A high-strength galvanized steel sheet includes a steel sheet having a chemical composition containing a predetermined component element, a mass ratio of a content of Si to a content of Mn in the steel (Si/Mn) being 0.1 or more and less than 0.2, and the balance: Fe and incidental impurities, and a steel structure in which an average grain size of inclusions containing at least one of Al, Si, Mg, and Ca and existing in an area extending from a surface to a position of ⅓ of a sheet thickness is 50 μm or less, and an average nearest distance between ones of the inclusions is 20 μm or more; and a galvanized layer provided on a surface of the steel sheet, in which an amount of diffusible hydrogen contained in the steel is less than 0.25 mass ppm, and a tensile strength is 1100 MPa or more.
US11560613B2	Martensitic stainless steel A martensitic stainless steel contains 0.20 mass %≤C≤0.60 mass %, 0.10 mass %≤N≤0.50 mass %, 14.00 mass %≤Cr≤17.00 mass %, 1.00 mass %≤Mo≤3.00 mass %, 0.20 mass %≤V≤0.40 mass %, Si≤0.30 mass %, Mn≤0.80 mass %, P≤0.040 mass %, S≤0.040 mass %, Cu≤0.25 mass %, Ni≤0.20 mass %, and the balance Fe with inevitable impurities.
US11560608B2	Cold-rolled flat steel product for packaging materials A cold-rolled flat steel product for packaging materials has a thickness of less than 0.6 mm, which has been cold-rolled from steel along a rolling direction (0°) and which has an excellent isotropy with respect to its mechanical properties.
US11560606B2	Methods of producing continuously cast hot rolled high strength steel sheet products Methods of producing high strength continuously cast hot rolled steel sheet products are disclosed. The methods include continuously casting a steel slab and then hot rolling with finish rolling on a hot strip mill, quenching on the hot strip mill to form a predominantly matrensitic microstructure, and performing a thermal cycling step including soaking at an intercritical temperature followed by holding at a lower temperature. The resultant hot rolled steel sheet products have a microstructure comprising ferrite and retained austenite. Steels processed in accordance with the present invention exhibit favorable combined ultimate tensile strength and total elongation (UTS·TE) properties, and may fall into the category of Generation 3 advanced high strength steels, desirable in various industries including automobile manufacturers.
US11560604B2	Ferritic stainless steel Provided is a ferritic stainless steel in which cracking is unlikely to be caused in the vicinity of a weld zone by the stress due to expansion, contraction, and deformation due to the thermal effect of welding in the case of performing welding after deep drawing and which is excellent in corrosion resistance in the vicinity of the weld zone.The ferritic stainless steel has a composition containing C: 0.001% to 0.020%, Si: 0.01% to 0.30%, Mn: 0.01% to 0.50%, P: 0.04% or less, S: 0.01% or less, Cr: 18.0% to 24.0%, Ni: 0.01% to 0.40%, Mo: 0.30% to 3.0%, Al: 0.01% to 0.15%, Ti: 0.01% to 0.50%, Nb: 0.01% to 0.50%, V: 0.01% to 0.50%, Co: 0.01% to 6.00%, B: 0.0002% to 0.0050%, and N: 0.001% to 0.020% on a mass basis, the remainder being Fe and inevitable impurities. The composition satisfies 0.30%≤Ti+Nb+V≤0.60%.
US11560602B2	Primer set for detecting trichophyton gene by lamp method, kit including same, and method for detecting trichophyton using same The present invention has an object to provide a simpler and quicker method for diagnosing tinea, method for detecting a Trichophyton, or method for detecting the Trichophyton gene. Use of at least four kinds of specific primers each designed based on a DNA sequence of the Trichophyton gene makes it possible to simply and quickly detect the Trichophyton gene.
US11560599B2	Onion discrimination method The present invention provides a means for accurately discriminating whether an onion is an onion with no pungent taste and/or tear-inducing property. The present invention relates to a method of discriminating traits of an onion, comprising a first determination step of determining presence of the nucleotide sequence of SEQ ID NO:1 corresponding to alliinase gene 1 in a nucleic acid derived from the onion, and a second determination step of determining presence of the nucleotide sequence of SEQ ID NO:2 corresponding to alliinase gene 2, wherein the onion is discriminated to be an onion with no pungent taste and/or tear-inducing property if the presence of the nucleotide sequence of SEQ ID NO:1 is not determined in the first determination step and the presence of the nucleotide sequence of SEQ ID NO:2 is determined in the second determination step.
US11560595B2	Method for preventing progression to type II Diabetes The method for preventing progression to Type II Diabetes includes determining whether a subject possesses a risk variant expression profile demonstrating dysregulation of the IL-33/ST2 axis, and providing an intervention to prevent progression to Type II Diabetes and/or to reverse prediabetes, including modifications of diet and exercise, administration of one or more pharmaceutical compounds, or a combination thereof. The method may be useful to reduce the risk of developing complications associated with Type II Diabetes or prediabetes, such as heart disease, stroke, or obesity. The pharmaceutical compound may be one or more pharmaceuticals capable of reducing circulating cholesterol, reducing blood glucose levels, reducing blood pressure, or a combination thereof.
US11560594B2	Methods of detecting osteoarthritis and predicting progression thereof Provided herein are methods and biomarkers useful for detecting and diagnosing osteoarthritis and predicting the progression of osteoarthritis in subjects. The diagnoses and predictions of prognosis may be used to develop treatment plans for subjects. Also included are methods of treating subjects and administering pharmaceuticals based on the diagnosis and prognosis predictions.
US11560593B2	Methods for spatial analysis using RNA-templated ligation Provided herein are methods of detecting an analyte of interest to interrogate spatial gene expression in a sample using RNA-templated ligation.
US11560590B2	Methods and compositions for sequencing complementary polynucleotides Disclosed herein, inter alia, are substrates, kits, and efficient methods of preparing and sequencing two or more regions of a double-stranded polynucleotide.
US11560588B2	Multiplex Q-PCR arrays This invention provides methods and systems for measuring the concentration of multiple nucleic acid sequences in a sample. The nucleic acid sequences in the sample are simultaneously amplified, for example, using polymerase chain reaction (PCR) in the presence of an array of nucleic acid probes. The amount of amplicon corresponding to the multiple nucleic acid sequences can be measured in real-time during or after each cycle using a real-time microarray. The measured amount of amplicon produced can be used to determine the original amount of the nucleic acid sequences in the sample. Also provided herein are biosensor arrays, systems and methods for affinity based assays that are able to simultaneously obtain high quality measurements of the binding characteristics of multiple analytes, and that are able to determine the amounts of those analytes in solution. The invention also provides a fully integrated bioarray for detecting real-time characteristics of affinity based assays.
US11560587B2	Spatially encoded biological assays The present invention provides assays and assay systems for use in spatially encoded biological assays. The invention provides an assay system comprising an assay capable of high levels of multiplexing where reagents are provided to a biological sample in defined spatial patterns; instrumentation capable of controlled delivery of reagents according to the spatial patterns; and a decoding scheme providing a readout that is digital in nature.
US11560586B2	Methods and processes for non-invasive assessment of genetic variations Provided herein are methods, processes and apparatuses for non-invasive assessment of genetic variations.
US11560585B2	Methods of identifying multiple epitopes in cells The invention provides methods, compositions, kits and devices for the detection of target molecules. In some embodiments, the invention allows for multiplexed target molecule detection.
US11560583B2	Heterologous carotenoid production in microorganisms Non-naturally occurring microorganisms are provided that produce C40 carotenoid compound(s), utilizing exogenously added enzyme activities. Methods of producing C40 carotenoid compounds in microbial cultures, and feed and nutritional supplement compositions that include the C40 carotenoid compounds produced in the microbial cultures, are also provided.
US11560581B2	Process for producing enzymes with a strain belonging to a filamentous fungus A process for producing cellulolytic and/or hemicellulolytic enzymes with a strain of microorganism belonging to the family of filamentous fungi. The process includes growing the fungi in an aqueous culture medium, in the presence of at least one carbon-based growth substrate, in a stirred and aerated bioreactor. It also includes the production of enzymes, starting with the aqueous culture medium in the presence of at least one inductive carbon-based substrate and also inducing the production of hydrophobins. Further, at least a portion of the hydrophobins produced in step (b) are reintroduced into the growth step (a).
US11560580B2	Process for production of a solid material containing isomaltulose crystals and trehalulose A process for producing a solid material comprising isomaltulose crystals and trehalulose, including: A) contacting an enzyme complex with a sucrose-containing solution; B) isomerizing at least a part of the sucrose to isomaltulose and trehalulose; C) separating off the enzyme complex to obatin a solution including isomaltulose, trehalulose and water; D) partially removing the water by evaporation to obtain a concentrated solution; E) bringing the concentrated solution to a temperature range of 30° C. to 63° C. and subsequently inducing isomaltulose crystallization in this temperature range followed by cooling, thereby obtaining a solid material including isomaltulose crystals and trehalulose.
US11560579B2	Method for pretreating lignocellulosic biomass The present invention describes a process for pretreatment of lignocellulosic biomass that comprises the step of contacting a lignocellulosic biomass with an ionic liquid consisting of a phthalic salt of dicholine in the weight ratio from 1:1 to 1:100 of biomass:ionic liquid, said step taking place for a period of time that varies from 0.4 to 48 hours and in a temperature range that varies from 60 to 200° C. Furthermore, the present invention also relates to the use of the pretreated lignocellulosic biomass in an enzymatic hydrolysis process.
US11560571B2	Simultaneous gene silencing and suppressing gene silencing in ihe same cell The present invention relates to genetically modified cells that are capable of optimal transgene expression by co-expressing a silencing suppressor whilst at the same time are also capable of silencing a gene, such as a naturally occurring gene of the cell. The present invention also relates to methods of producing the modified cells, as well as relates to processes for obtaining a genetically modified cell with a desired property.
US11560570B2	Plant promoter for transgene expression This disclosure concerns compositions and methods for promoting transcription of a nucleotide sequence in a plant or plant cell, employing a promoter from a GmTEFs1 gene. Some embodiments relate to a promoter or a 5′ UTR from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences. Other embodiments relate to a 3′ UTR or a terminator from a GmTEFs1 gene that functions in plants to promote transcription of operably linked nucleotide sequences.
US11560569B2	Promoter, promoter control elements, and combinations, and uses thereof The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the promoters, control elements, or fragments thereof. The invention further relates to the use of the present promoters or promoter control elements to modulate transcript levels in plants, and plants containing such promoters or promoter control elements.
US11560567B2	Genetic elements driving circular RNA translation and methods of use Provided herein are recombinant circular RNA (circRNA) molecules comprising an internal ribosome entry site (IRES) operably linked to a protein-coding nucleic acid sequence. The IRES includes at least one RNA secondary structure element; and a sequence region that is complementary to an 18S ribosomal RNA (rRNA). Methods of producing a protein in a cell using the recombinant circRNA molecules are also provided.
US11560565B2	Electrochemical detection nanostructure, systems, and uses thereof Described herein are DNA-nanostructures that can be used in an assay to detect and/or quantify an analyte of interest. Aspects of the DNA-nanostructure can include a single DNA molecule composed of hairpin structural motifs, an anchor recognition moiety, and a signal moiety, where the anchor recognition moiety and the signal moiety are in effective proximity to each other such that the tethered diffusion of the signal molecule can be altered based upon binding status of the anchor recognition moiety. Also described herein are methods of making and using the DNA-nanostructures.
US11560564B2	Aptamers for targeting HPV16-positive tumor cells A composition for binding to human papillomavirus type 16 (HPV16)-positive tumor cells, the composition including a DNA aptamer. The DNA aptamer includes one of SEQ ID NO: 1 and SEQ ID NO: 2.
US11560562B2	Large-scale synthesis of messenger RNA The present invention provides methods for large-scale production of a composition enriched for full-length mRNA molecules using an SP6 RNA polymerase and compositions produced using such methods and uses thereof.
US11560557B2	Acoustic wave based particle agglomeration Articles of manufacture, including an apparatus for acoustic wave based agglomeration, are provided. The apparatus may include a well and an acoustic wave device. The well may be configured to hold a suspension that includes a plurality of particles. The acoustic wave device may be configured to generate a plurality of acoustic waves. The plurality of acoustic waves inducing acoustic streaming within the suspension. The acoustic streaming agitating the suspension to form an agglomerate comprising at least a portion of the plurality of particles. Methods for acoustic wave based agglomeration are also provided.
US11560554B2	Lysosomal storage disease enzymes The present invention provides compositions of recombinant human lysosomal acid lipase having particular glycosylation patterns for internalization into target cells, a vector containing the nucleic acid encoding human lysosomal acid lipase, a host cell transformed with the vector, pharmaceutical compositions comprising the recombinant human lysosomal acid lipase and method of treating conditions associated with lysosomal acid lipase deficiency.
US11560546B2	Methods for neural conversion of human embryonic stem cells The present invention relates generally to the field of cell biology of stem cells, more specifically the directed differentiation of pluripotent or multipotent stem cells, including human embryonic stem cells (hESC), somatic stem cells, and induced human pluripotent stem cells (hiPSC) using novel culture conditions. Specifically, methods are provided for obtaining neural tissue, floor plate cells, and placode including induction of neural plate development in hESCs for obtaining midbrain dopamine (DA) neurons, motor neurons, and sensory neurons. Further, neural plate tissue obtained using methods of the present inventions are contemplated for use in co-cultures with other tissues as inducers for shifting differentiation pathways, i.e. patterning.
US11560539B2	Reversible liquid filtration system A reversible liquid filtration system for cell culture perfusion comprises: a bioreactor vessel (B4), for storing the cell culture (L4); a perfusion pump (P7), comprising a reciprocable element (P71) which is movable in opposing first and second pumping directions (dF, dR); a filter (F4); and first and second bi-directional valves (BV1, BV2), each selectively controllable between open and closed positions. The perfusion pump (P7), the filter (F4), and the first and second bi-directional valves (BV1, BV2), together comprise a fluidic circuit in communication with the bioreactor vessel (B4). The bi-directional valves (BV1, BV2) are controllable to open and close in co-ordination with the reciprocating perfusion pump (P7), in order to enable both a two-way filtering flow around the fluidic circuit and also an alternating filtering flow between the bioreactor vessel (B4) and the perfusion pump (P7).
US11560533B2	Post chemical mechanical planarization (CMP) cleaning Provided are formulations that offer a high cleaning effect on inorganic particles, organic residues, chemical residues, reaction products on the surface due to interaction of the wafer surface with the Chemical Mechanical Planarization (CMP) slurry and elevated levels of undesirable metals on the surface left on the semiconductor devices after the CMP. The post-CMP cleaning formulations comprise one or more organic acid, one or more polymer and a fluoride compound with pH<7 and optionally a surfactant with two sulfonic acid groups.
US11560531B2	Spray container comprising a detergent composition The need for a container and detergent composition which exhibit good cleaning, including on greasy soils, and good surface shine, while also maintaining spray visibility on the treated hard surface, is met by formulating an aqueous detergent composition using a low level of surfactant system, an aminoalcohol solvent, and a glycol ether solvent, at the specified ratios.
US11560530B2	Surfactants based on monounsaturated fatty alcohol derivatives Surfactant compositions comprising an alkoxylate, a sulfate, or ether sulfate of a C10-C12 monounsaturated alcohol are disclosed. The alkoxylate, sulfate, or ether sulfate may derive from undecylenic acid or undecylenic alcohol. Compared with their saturated analogs, the monounsaturated alkoxylates, sulfates, and ether sulfates are less irritating, making them valuable for personal care, laundry, cleaners, and other household applications. Microscopy studies show that the alkoxylates, sulfates, and ether sulfates have favorable phase behavior over a wide range of actives levels, expanding opportunities for products with greater compaction. When combined with cationic surfactants, the alkoxylates, sulfates, and ether sulfates exhibit synergy, and they have improved solubility compared with their saturated analogs. The surfactants find value for the personal care, laundry and cleaning, emulsion polymerization, agricultural products, oilfield applications, and specialty foams industries.
US11560527B2	Lubricating oil composition for transmission A lubricating oil composition for a transmission, the composition including: (A) a lubricant base oil comprising a mineral base oil and/or a synthetic base oil; and (B) a poly(meth)acrylate having a weight average molecular weight of no more than 25,000, wherein the composition has a kinematic viscosity at 100° C. of 2.5 to 4.9 mm2/s.
US11560524B2	Coal powder pretreatment method and coal powder gasification method Disclosed are a pulverized coal preprocessing method and a pulverized coal gasifying method. The pulverized coal preprocessing method comprises the following steps: (1) performing pore broadening on pulverized coal to obtain preprocessed pulverized coal; (2) loading alkali metal ions into the preprocessed pulverized coal under an ion exchange condition to obtain alkali metal loaded pulverized coal. The method further comprises loading a chrome complex into the alkali metal loaded pulverized coal obtained in described step (2). In gasification, the pulverized coal loaded with alkali metal potassium and chrome catalysts obtained by the method has the advantages of high sulphur removal rate, high carbon conversion rate, short gasifying reaction time and high methane production.
US11560522B2	Method of making a hydrodesulfurization catalyst with a structural directing surfactant A method of preparing hydrodesulfurization catalysts having cobalt and molybdenum sulfide deposited on a support material containing mesoporous silica. The method utilizes a sulfur-containing silane that dually functions as a silica source and a sulfur precursor. The method involves an one-pot strategy for hydrothermal treatment and a single-step calcination and sulfidation procedure. The application of the hydrodesulfurization catalysts in treating a hydrocarbon feedstock containing sulfur compounds to produce a desulfurized hydrocarbon stream is also specified.
US11560521B2	High performance process oil Naphthenic process oils are made by blending one or more naphthenic vacuum gas oils in one or more viscosity ranges with a high CA content ethylene cracker bottoms, slurry oil, heavy cycle oil or light cycle oil feedstock to provide at least one blended oil, and hydrotreating the at least one blended oil to provide an enhanced CA content naphthenic process oil. The order of the vacuum distillation and blending steps may be reversed.
US11560519B2	Transfer hydrogenation of heavy hydrocarbons with hydrogen-donor solvents Processes for converting the coal-derived heavy-oil fraction of syncrude to polyols are described. The processes involve mixing a feed stream comprising the coal-derived heavy-oil fraction with an alcohol and aqueous sulfuric acid, heating the mixture, reacting the coal-derived heavy-oil fraction with ozone, and reacting the ozonated heavy-oil fraction with glycerin to form the polyol. In some cases, the ozonated heavy-oil fraction can be neutralized before reacting the ozonated heavy-oil fraction with the glycerin.
US11560517B2	Photoreactive liquid crystal composition, display element, optical element, method for manufacturing display element, and method for manufacturing optical element A photoreactive liquid crystal composition containing (A) a photoreactive polymer liquid crystal which includes a photoreactive side chain in which at least one type of reaction selected from (A-1) photocrosslinking and (A-2) photoisomerization occurs, and (B) a low molecular weight liquid crystal. An optical element or display element is formed having a liquid crystal cell including the photoreactive liquid crystal composition.
US11560515B2	Lutetium based oxyorthosilicate scintillators codoped with transition metals Codoped lutetium-based oxyorthosilicate scintillators (e.g., lutetium oxyorthosilicase (LSO) and lutetium-ytrrium oxyorthosilicate (LYSO) scintillators) codoped with transition metal ions (e.g., Cu2+) are described. The codoping can alter one or more optical and/or scintillation property of the scintillator material. For example, the codoping can increase scintillation light yield and/or decrease scintillation decay time. Radiation detectors comprising the scintillators, methods of detecting high energy radiation using the radiation detectors, and methods of altering one or more scintillation and/or optical properties of a lutetium-based oxyorthosilicate scintillator are also described.
US11560514B2	Method for producing β-sialon fluorescent material Provided is a method for producing a β-sialon fluorescent material, comprising preparing a composition containing a silicon nitride that contains aluminium, oxygen, and europium; heat-treating the composition at a temperature in a range of 1300° C. or more and 1600° C. or less to obtain a heat-treated product; subjecting the heat-treated product to a temperature-decrease of from the heat treatment temperature to 1000° C. as a first temperature-decrease step; and subjecting the heat-treated product to a temperature-decrease of from 1000° C. to 400° C. as a second temperature-decrease step. The first temperature-decrease step has a temperature-decrease rate in a range of 1.5° C./min or more and 200° C./min or less, and the second temperature-decrease step has a temperature-decrease rate in a range of 1° C./min or more and 200° C./min or less.
US11560510B2	Aqueous fracturing fluid composition and fracturing process using the composition Fracturing fluid comprising, in solution in water, a proppant and an associative amphoteric polymer, the said polymer and comprising: 0.01 to 10 mol % of at least one cationic monomer containing a hydrophobic chain, from 0.09 to 89.99 mol % of at least one anionic monomer, and from 10 to 99.9 mol % of at least one nonionic water-soluble monomer, the total amount of monomer being 100 mol %. Fracturing process using this fluid.
US11560505B2	Heat transfer fluids containing synergistic blends of corrosion inhibitor formulations Corrosion inhibitor formulations for use in heat transfer fluids include: (a) an optionally substituted benzoic acid or a salt thereof; (b) at least a first n-alkyl monocarboxylic acid or a salt thereof and a second n-alkyl monocarboxylic acid or a salt thereof, the first n-alkyl monocarboxylic acid and the second n-alkyl monocarboxylic acid being different; and (c) an azole compound. A ratio of weight percent of the first n-alkyl monocarboxylic acid or the salt thereof to weight percent of the second n-alkyl monocarboxylic acid or the salt thereof ranges from about 1:0.75 to about 1:2.00. A ratio of weight percent of the benzoic acid or the salt thereof to combined weight percent of the first n-alkyl monocarboxylic acid or the salt thereof and the second n-alkyl monocarboxylic acid or the salt thereof ranges from about 1:0.30 to about 1:2.25.
US11560504B2	Salt hydrate-based phase change thermal energy storage and encapsulation thereof Among other things, the present disclosure relates to phase change material (PCM) composites composed of an PCM mixed with a nucleating agent contained within the pores of a graphite matrix and/or a hydrogel. The process to create these PCM composites includes coating the surface of graphite with a surfactant, compressing the graphite to form a matrix, then filling the graphite matrix with the PCM.
US11560500B2	Optical adhesive and optical laminates and lenses formed with same The present invention pertains to polyurethane-urea based optical adhesives for formation of optical film laminates, optically functional film laminates, and ophthalmic or eyeglass lenses employing the same and methods for producing the same.
US11560496B2	Self-wetting adhesive composition According to various embodiments of the present disclosure, a composition includes about 5 to about 40 parts by weight of a solute copolymer component. The solute component optionally has one Tg or Tm of at least 25° C. The composition further includes about 60 to about 95 parts by weight of a solvent monomer. The solvent monomer component includes (meth)acrylate monomers and a multifunctional acrylate. The sum of the solute copolymer component and the solvent monomer component is 100 parts by weight. The composition further includes about 5 to about 100 parts of a plasticizer, relative to the 100 parts.
US11560494B2	Coating composition, surface treatment agent containing said composition, and article which is surface-treated with said surface treatment agent According to the present invention, a surface treatment agent which contains a coating composition that contains (A) one or more compounds selected from among organosilane or siloxane compounds represented by formula (1) and partial (hydrolysis) condensation products of the compounds and (B) one or more compounds selected from among silane or siloxane compounds represented by formula (2) and partial (hydrolysis) condensation products of the compounds at a mass ratio of from 50:50 to 90:10 is able to form a cured coating film that has excellently low fingerprint visibility. (In formula (1), A represents —C(═O)OR1, —C(═O)NR12, —C(═O)SR1 or —P(═O)(OR1)2; R1 represents H, an alkyl group, an aryl group or an aralkyl group; Y represents a divalent organic group; R represents an alkyl group or a phenyl group; X represents a hydroxyl group or a hydrolyzable group; and n is 1-3.) (In formula (2), Rf represents a perfluoroalkylene group or a divalent perfluoropolyether group.)
US11560490B2	Water-based ink composition for ballpoint pen and water-based ballpoint pen using the same The present invention provides a water-based ink composition for a ballpoint pen that is less likely to cause bleeding of a written trace in writing, provides a favorable written trace without causing no blurring or line splitting, and excels in the storage stability of the ink composition; and a water-based ballpoint pen using the ink composition.A water-based ink composition for a ballpoint pen comprising water, a coloring agent, a copolymer having a specific structure; and a water-based ballpoint pen using the ink composition.
US11560483B2	Compositions for inhibiting corrosion The present disclosure relates to agents, compositions, and methods for inhibiting corrosion in various substrates, for example in metal substrates. The present disclosure also relates to compositions for inhibiting corrosion comprising at least one organic heterocyclic compound and at least one metal salt or mixed metal salt selected from rare earth, alkali earth and transition metals.
US11560479B2	Bitumen/polymer composition having improved mechanical properties The invention relates to a bitumen/polymer composition containing at least one elastomer of the heat-crosslinkable S-B-S type, where S is a styrene or other vinylaromatic polymer block, and B is a polybutadiene block, the composition comprising an adjuvant of the olefin polymer type and having improved mechanical properties. The invention also relates to the use of the compositions in the fields of road applications such as hot mixes; warm mixes; cold mixes, for example cold-cast mixes or emulsion gravel; or surface dressings, for example fluxed bitumen or emulsions; and in the fields of industrial applications, for example in the production of inside and outside coatings.
US11560474B2	Information carrying card comprising a cross-linked polymer composition, and method of making the same The disclosure provides a cross-linkable polymer composition, a core layer for an information carrying card comprising such cross-linked composition, resulting information carrying card, and methods of making the same. An information carrying card includes a body defining a first cavity and a second cavity. The first cavity has a first area and the second cavity has a second area. The first cavity is continuous with the second cavity and the second area is less than the first area. A circuit element is disposed within the first cavity.
US11560473B2	Dimensionally stable acrylic alloy for 3-D printing The invention relates to an acrylic alloy composition that can be 3-D printed by a material extrusion additive manufacturing process, to an acrylic filament that has a very uniform diameter useful in the extrusion additive manufacturing process, to acrylic articles made from the acrylic alloy composition by a material extrusion additive process, and to a material extrusion additive manufacturing process for producing the acrylic articles. The acrylic alloy composition is an alloy of an acrylic polymer, and a low melt viscosity polymer, such as polylactic acid. The alloy may optionally be impact modified, preferably with hard core core-shell impact modifiers.
US11560471B2	Patient support formed from an elastomeric composition including a polymer blend of seeps copolymers This disclosure provides a person support formed from an elastomeric composition. The elastomeric composition includes a polymer blend with the polymer blend consisting essentially of a first and second SEEPS copolymer. The first and second SEEPS copolymers are present in the polymer blend in an amount of from 75 to 95 percent by weight and 5 to 25 percent by weight, respectively, based on the total weight of the polymer blend. In addition, the sum of the first and second SEEPS copolymers in the polymer blend is 100 percent by weight. The first and second SEEPS copolymers have a weight average molecular weight of weight of at least 200,000 and 125,000 to 175,000, respectively. The disclosure also provides a patient support for supporting a patient with the patient support formed from the elastomeric composition.
US11560470B2	Thermoplastic elastomer composition Provided is a thermoplastic elastomer composition capable of producing a molded article having a good appearance such as surface smoothness and excellent bondability to another member, the thermoplastic elastomer composition comprising: an ethylene-based polymer (A); and a propylene-based polymer (B), wherein a melt viscosity of the thermoplastic elastomer composition measured at a temperature of 220° C. and a shear rate of 12 sec−1 is 2,500 Pa·sec or less; the thermoplastic elastomer composition has a sea-island structure; and an island portion has a volume average particle diameter of 2.1 μm or more and a particle diameter dispersion D of 7.0 or less.
US11560469B2	Polypropylene composition and thermoformed sheet thereof The present invention relates to a polypropylene composition for thermoforming comprising: from 50% by weight to at most 90% by weight of a polypropylene A, wherein polypropylene A is a polypropylene random copolymer, based on the total weight of the polypropylene composition; and from 10% by weight to at most 50% by weight of a polypropylene B, wherein polypropylene B is a polypropylene homopolymer, based on the total weight of the polypropylene composition; wherein the melt flow index of polypropylene B is at most 1.0 g/10 min, as measured according to the method of standard ISO 1133, condition M, at 230° C. and under a load of 2.16 kg; and wherein the ratio of the melt flow index of polypropylene A to the melt flow index of polypropylene B is at least 80.
US11560465B2	Composition for curable resin, cured product of said composition, method of producing said composition and said cured product, and semiconductor device Provided is a curable resin composition for obtaining a cured product that can satisfy both high heat resistance and high adhesiveness to metal, a cured product thereof, and methods of producing the curable resin composition and the cured product, and a semiconductor device using the cured product as a sealant. A curable resin composition containing (A) a multifunctional benzoxazine compound having two or more benzoxazine rings, (B) a multifunctional epoxy compound having at least one norbornane structure and at least two epoxy groups, (C) a curing agent, (D) a triazole-based compound, and optionally (E) a curing accelerator and (F) an inorganic filler, a cured product thereof, and methods of producing the curable resin composition and the cured product. A semiconductor device in which a semiconductor element is disposed in a cured product obtained by curing a curable resin composition containing components (A) to (D), and optionally components (E) and (F).
US11560453B2	Polyorganosilsesquioxane, hard coat film, adhesive sheet, and laminate Provided is a polyorganosilsesquioxane capable of forming, when cured, a cured product that offers high surface hardness and good heat resistance, is highly flexible, and has excellent processability. The present invention relates to a polyorganosilsesquioxane including a constitutional unit represented by Formula (1). The polyorganosilsesquioxane includes a constitutional unit represented by Formula (I) and a constitutional unit represented by Formula (II) in a mole ratio of the constitutional unit represented by Formula (I) to the constitutional unit represented by Formula (II) of 5 or more. The polyorganosilsesquioxane has a total proportion of the constitutional unit represented by Formula (1) and a constitutional unit represented by Formula (4) of 55% to 100% by mole based on the total amount (100% by mole) of all siloxane constitutional units. The polyorganosilsesquioxane has a number-average molecular weight of 1000 to 3000 and a molecular-weight dispersity (weight-average molecular weight to number-average molecular weight ratio) of 1.0 to 3.0. [R1SiO3/2] (1) [Chem. 2] [RaSiO3/2] (I) [Chem. 3] [RbSiO(ORc)] (II) [Chem. 4] [R1SiO(ORc)] (4)
US11560448B2	Antimony free flame-retarded epoxy compositions A curable epoxy composition suitable for surface application, comprising one or more epoxy resin (s); 2, 4, 6-tribromophenyl end-capped tetrabromobisphenol A epoxy-based flame retardant; and phosphorus-containing compound selected from the group consisting of one or more of: ammonium polyphosphate; resorcinol bis (diphenyl phosphate); and liquid alkylated triphenyl phosphate ester. The composition is substantially Sb2O3-free.
US11560446B2	Polyurethane foam article and method of forming same A polyurethane foam article comprises the reaction product of an isocyanate component and isocyanate-reactive composition in the presence of a blowing agent. The isocyanate component includes an isocyanate prepolymer comprising the reaction product of a first polyether polyol and a methylene diphenyl diisocyanate. The isocyanate-reactive composition comprises a second polyether polyol having secondary terminal hydroxyl groups and an amine-initiated catalytic polyether polyol having primary hydroxyl groups. A method of making the polyurethane foam article comprises the steps of reacting the first polyether polyol and methylene diphenyl diisocyanate to form the isocyanate prepolymer and reacting the isocyanate prepolymer with the isocyanate-reactive composition in the presence of the blowing agent to form the polyurethane foam article.
US11560445B2	Silylated polyurethanes and methods for preparing thereof The invention relates to a silylated polyurethane obtainable by reacting: d) at least one polyol having a number average molecular weight of from 1000 to 50,000 g/mol; e) at least one polyisocyanate, preferably diisocyanate; and f) at least one tertiary hydroxyl functional alkoxysilane of the general formula (I) wherein R1 is selected from the group consisting of hydrogen and a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R2 and R3 are same or different and are, independent from one another, selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R4 is selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R5 is selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; R6 and R7 are same or different and are, independent from one another, selected from a linear or branched, substituted or unsubstituted hydrocarbon residue having 1 to 20 carbon atoms; and n is 1, 2 or 3, a method for preparing thereof, a curable composition comprising the thereby obtained silylated polyurethane, and its use.
US11560443B2	Grafted polyvinyl alcohol polymer, formulations containing the same, and creping methods A grafted polyvinyl alcohol polymer includes a polyvinyl alcohol main chain and a plurality of side chains grafted to the polyvinyl alcohol main chain. One or more of the side chains from the plurality of side chains include one or more units selected from: an aliphatic carboxylic acid, an aliphatic amide, an amino alkyl (meth)acrylate, a hydroxylated alkyl (meth)acrylate, or any combinations thereof. The grafted polyvinyl alcohol polymer can be included in a formulation that also includes water, and the formulation can be used as an adhesive in a creping process.
US11560437B2	Stable multispecific antibodies The invention relates to multispecific antibody constructs comprising Fab fragments having a particular set of mutations at the interface of the CH1 and CL domains, the mutations preventing heavy chain/light chain mispairing.
US11560436B2	Anti-VWF D'D3 single-domain antibodies fuse to clotting factors The invention relates to isolated single-domain antibodies (sdAb) directed against von Willebrand Factor (VWF) D′D3 domain and chimeric polypeptides comprising thereof such as blood clotting factors and their uses in therapy such as in the prevention and treatment of hemostatic disorders. The invention also relates to a method of extending or increasing half-life of a therapeutic polypeptide comprising a step of adding to the polypeptide sequence of said therapeutic polypeptide at least one sdAb directed against VWF D′D3 domain.
US11560429B2	Anti PD-1 antibodies The present invention relates to antibodies and antigen-binding fragments thereof that bind to PD-1, and to methods of using such antibodies and antigen-binding fragments. For example, the present invention provides humanized anti-PD-1 antibodies and methods of use thereof.
US11560424B2	Antibodies to alpha-synuclein and uses thereof The invention provides antibodies that specifically bind human α-synuclein with a high affinity and reduces α-synuclein spreading in vivo, recombinant polypeptides comprising said antibodies or antigen-binding fragment thereof and methods for generating such polypeptides, as well as compositions and methods for generating α-synuclein antibodies, and methods of using α-synuclein antibodies for the treatment of diseases of the central nervous system, in particular alpha-synucleinopathies.
US11560423B2	Isolated monoclonal antibodies and/or antigen-binding fragments thereof against indoxyl sulfate and uses thereof The present invention relates to isolated monoclonal antibodies (mAbs) and/or antigen-binding fragments thereof that specifically recognize indoxyl sulfate, a protein-bound uremic toxin, and uses of such isolated anti-IS mAbs and/or antigen-binding fragments thereof to create immunoassay methods applied in theragnosis of IS-related diseases.
US11560420B2	Method for producing antibodies using ovine B-cells and uses thereof Herein is reported a cultivation system for cultivating a pool of ovine B-cells or single deposited ovine B-cells in the presence of phorbol myristate acetate (PMA).
US11560418B2	Methods and compositions for modified factor IX fusion proteins The present invention provides Factor IX fusion proteins with higher specific activity and a longer useful clotting function relative to wild type or non-modified Factor IX protein.
US11560417B2	Isolated polypeptides of CD44 and uses thereof Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.
US11560416B2	Method for producing dual function proteins and its derivatives A method for producing a dual function protein includes a biologically active protein and an FGF21 mutant protein. The method allows stable production of a target protein by effectively preventing decomposition of the target protein, and thus has a high potential for commercial usage.
US11560415B2	Method of promoting regulatory T-cell proliferation Described herein are immunosuppressive molecules including immunosuppressive variants of IL-2, and use of such molecules to treat inflammatory and autoimmune disorders.
US11560410B2	Modified biotin-binding protein, fusion proteins thereof and applications The disclosure provides modified biotin-binding proteins which can be expressed in soluble form in high yield in bacteria. Also provided are fusion proteins comprising the modified biotin-binding protein and an antigen. The disclosure further provides non-hemolytic variants of alpha-hemolysin from S. aureus and fusion protein comprising non-hemolytic variant of alpha-hemolysin and a biotin-binding domains. Immunogenic compositions comprising the proteins are also disclosed and use of such immunogenic compositions for inducing an immune response or for vaccinating a subject are also disclosed.
US11560409B2	Epitope focusing by variable effective antigen surface concentration The present disclosure provides compositions and methods for the generation of an antibody or immunogenic composition, such as a vaccine, through epitope focusing by variable effective antigen surface concentration. Generally, the composition and methods of the disclosure comprise three steps: a “design process” comprising one or more in silico bioinformatics steps to select and generate a library of potential antigens for use in the immunogenic composition; a “formulation process”, comprising in vitro testing of potential antigens, using various biochemical assays, and further combining two or more antigens to generate one or more immunogenic compositions; and an “administering” step, whereby the immunogenic composition is administered to a host animal, immune cell, subject or patient. Further steps may also be included, such as the isolation and production of antibodies raised by host immune response to the immunogenic composition.
US11560406B2	Anti-androgen peptides and uses thereof in cancer therapy The present invention relates to isolated or purified or partially purified peptide derived molecules having the following general formula (S1): X-[(Pro)n-His-Pro-His-Ala-Arg-Ile-Lys]m-Y. The peptides are for medical use, in particular as anti-tumoral agents.
US11560403B2	1,2,4-oxadiazole compounds as inhibitors of CD47 signaling pathways The present invention relates to compounds of formula (I), compositions, methods and uses involving the said formula (I) that inhibit CD47 signaling pathway. The present invention also relates to methods of making such compounds and their uses for the treatment of diseases or disorders mediated by CD47.
US11560402B2	Method for cleavage of solid phase-bound peptides from the solid phase The invention relates to a method for the cleavage of a solid phase-bound polypeptide from the solid phase, the method comprising contacting the solid phase, to which the polypeptide is bound, with a composition consisting essentially of trifluoroacetic acid and 1,2-ethanedithiol, at a temperature in the range of about 23° C. to about 29° C.
US11560399B2	Process for preparing mannose derivatives The invention relates to a process to prepare a compound of the following formula (I): (I), in which P represents a protective group of a hydroxyl function which is a —COR1 group with R1 representing an aryl or a (C1C6)alkyl, R represents a hydrogen atom or a protective group of a terminal alkyne, from mannose, comprising the following steps: (a) protecting the 5 hydroxyl groups of the mannose by a protective group P; (b) coupling the protected mannose obtained at step (a) with a compound of the following formula (II). The present invention also relates to a compound of formula (IIIa).
US11560397B2	Group VI precursor compounds The invention provides a facile process for preparing various Group VI precursor compounds, set forth below as Formula (I), useful in the vapor deposition of certain Group VI metals onto solid substrates, especially microelectronic semiconductor device substrates. Also provided is a process for the preparation of such precursor compounds. Additionally, the invention provides a method for vapor deposition of Group VI metals onto microelectronic device substrates utilizing the precursor compounds of the invention.
US11560396B2	Diphosphites having an open and a closed 2,4-methylated outer unit Diphosphites having an open and a closed 2,4-methylated outer unit and use thereof in hydroformylation.
US11560394B2	Metal complex comprising amidine and indole fused cyclopentadienyl ligands A metal complex of the formula (1) InCyLMZp (1), wherein M is a group 4 metal, Z is an anionic ligand, p is number of 1 to 2, InCy is an indole fused cyclopentadienyl-type ligand of the formula (2) wherein R1 independently is a C1-C4-alkyl, m is a number of 0 to 4, R2 is a C1-C10-alkyl, C5-C10-cycloalkyl, or a C6-C10-aryl unsubstituted or substituted with C1-C10-alkyl or C1-C4-dialkyl amino, R3, R4 and R5 each is independently selected from hydrogen, C1-C4-alkyl, C6-C10-aryl unsubstituted or substituted with C1-C4-alkyl, halide, or both of C1-C4-alkyl and halide and, L is an amidinate ligand of the formula (3a) wherein the amidine-containing ligand (3a) is bonded to the metal M via the imine nitrogen atom N2, wherein R7 is independently selected from C1-C4-alkyl and halide and q is a number of 0 to 4, Sub4 is a cyclic or linear aliphatic or aromatic substituent.
US11560392B2	Boron-containing compounds Described herein are boron-containing compounds, compositions, and methods for their preparation.
US11560390B2	Compounds for the treatment of cancer and inflammatory disease Provided herein are compounds that inhibit the phosphorylation of MAPK and thus are useful in compositions and methods for treating cancer and inflammatory disease.
US11560388B2	Anthelmintic aza-benzothiophene and aza-benzofuran compounds This invention provides for compounds of the formula: wherein the variables are defined herein, or a stereoisomer, tautomer, N-oxide, hydrate, solvate, or salt thereof, compositions comprising these compounds, and method for the treatment, control or prevention of a parasitic infestation or infection in an animal in need thereof by administering an effective amount of these compounds to said animal.
US11560387B2	Thermally sensitive protecting groups for cysteine, and manufacture and use thereof In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
US11560386B2	Modulators of the beta-3 adrenergic receptor useful for the treatment or prevention of disorders related thereto The present invention relates to compounds of Formula (Ia) and pharmaceutical compositions thereof that modulate the activity of the beta-3 adrenergic receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to methods useful in the treatment of a beta-3 adrenergic receptor-mediated disorder, such as, heart failure; cardiac performance in heart failure; mortality, reinfarction, and/or hospitalization in connection with heart failure; acute heart failure; acute decompensated heart failure; congestive heart failure; severe congestive heart failure; organ damage associated with heart failure (e.g., kidney damage or failure, heart valve problems, heart rhythm problems, and/or liver damage); heart failure due to left ventricular dysfunction; heart failure with normal ejection fraction; cardiovascular mortality following myocardial infarction; cardiovascular mortality in patients with left ventricular failure or left ventricular dysfunction; left ventricular failure; left ventricular dysfunction; class II heart failure using the New York Heart Association (NYHA) classification system; class III heart failure using the New York Heart Association (NYHA) classification system; class IV heart failure using the New York Heart Association (NYHA) classification system; LVEF<40% by radionuclide ventriculography; LVEF≤35% by echocardiography or ventricular contrast angiography; and conditions related thereto.
US11560382B2	Organic compounds This invention relates to particular substituted heterocycle fused gamma-carbolines, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving 5-HT2A receptor, serotonin transporter (SERT) and/or pathways involving dopamine D1/D2 receptor signaling systems, and/or the treatment of residual symptoms.
US11560381B1	Compounds and uses thereof The present invention relates to compositions and methods for the treatment of BAF-related disorders, such as cancers and viral infections.
US11560380B2	Substituted naphthalene diimides and their use The present invention relates to naphthalene diimides, NDIs, and methods of synthesising them. The NDIs have DNA-quadruplex binding and stabilising activity, and potential in treatment of pancreatic, prostate, and other human cancers. The NDIs are a compound of Formula I.
US11560376B2	Amino acid compounds and methods of use The invention relates to compounds of formula (A) and formula (I): or a salt thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).
US11560375B2	Composition and method for treating metabolic disorders Bromocriptine citrate administered to a vertebrate, animal or human, can be used for any purpose including, e.g., the long-term modification and regulation of metabolic disorders, including prediabetes, obesity, insulin resistance, hyperinsulinemia, hyperglycemia and type 2 diabetes mellitus (T2DM) and/or, e.g., the treatment of other medical disorder(s) including immune or endocrine disorders or diseases. Bromocriptine citrate is administered over a limited or extended period at a time of day dependent on re-establishing the normal circadian rhythm of central dopaminergic activity of healthy members of a similar species and sex. Insulin resistance, hyperinsulinemia and hyperglycemia, T2DM, prediabetes, MS or all, can be controlled in humans on a long term basis by such treatment inasmuch as the daily administration of bromocriptine citrate resets neuronal activity timing in the neural centers of the brain to produce long term effects.
US11560371B2	Cereblon binding compounds, compositions thereof, and methods of treatment therewith Provided herein are piperidine dione compounds having the following structure: wherein R1, R2, R3, R4, L, V, X, A, A′, a and m are as defined herein, compositions comprising an effective amount of a piperidine dione compound, and methods for treating or preventing an androgen receptor mediated disease.
US11560369B2	Crystalline forms and processes for the preparation of cannabinoid receptor modulators The present invention relates to crystalline forms of (1aS,5aS)-2-(4-oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa[a]pentalene-4-carboxylic acid ((S)-1-hydroxymethyl-2,2-dimethyl-propyl)-amide (Compound 1) and pharmaceutical compositions thereof that modulate the activity of the cannabinoid CB2 receptor and are therefore useful in the treatment of CB2 receptor-mediated disorders, for example, osteoarthritis; pain; hyperalgesia; allodynia; inflammatory hyperalgesia; neuropathic hyperalgesia; acute nociception; osteoporosis; multiple sclerosis-associated spasticity; autoimmune disorders; allergic reactions; CNS inflammation for example; atherosclerosis; undesired immune cell activity, and inflammation associated with a disorder selected from: osteoarthritis, anaphylaxis, Behcet's disease, graft rejection, vasculitis, gout, spondylitis, viral disease, bacterial disease, lupus, inflammatory bowel disease, autoimmune hepatitis, and type 1 diabetes mellitus; age-related macular degeneration; cough; leukemia; lymphoma; CNS tumors; prostate cancer; Alzheimer's disease; stroke-induced damage; dementia; amyotrophic lateral sclerosis; and Parkinson's disease.
US11560367B2	Pyrrolidinones and a process to prepare them This application is directed to a compound of Formula II Also disclosed is a process for preparing a compound of Formula II comprising using the compounds of Formulae IV and V Also disclosed is a method for preparing a compound of Formula I comprising contacting a compound of Formula II with a compound of a compound of Formula VI wherein A1, A2 A3, R1, R2, R3a, R3b, R4, B1, B2 and B3, are as defined in the disclosure.
US11560366B2	Bicyclo[1.1.1]pentane inhibitors of dual leucine zipper (DLK) kinase for the treatment of disease Disclosed herein are compounds which inhibit the kinase activity of dual leucine zipper (DLK) kinase (MAP3K12), pharmaceutical compositions, and methods of treatment of DLK-mediated diseases, such as neurological diseases that result from traumatic injury to central nervous system and peripheral nervous system neurons (e.g. stroke, traumatic brain injury, spinal cord injury), or that result from a chronic neurodegenerative condition (e.g. Alzheimer's disease, frontotemporal dementia, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, spinocerebellar ataxia, progressive supranuclear palsy, Lewy body disease, Kennedy's disease, and other related conditions), from neuropathies resulting from neurological damage (chemotherapy-induced peripheral neuropathy, diabetic neuropathy, and related conditions) and from cognitive disorders caused by pharmacological intervention (e.g. chemotherapy induced cognitive disorder, also known as chemobrain).
US11560363B2	Synthesis of esuberaprost prodrugs Provided are novel prodrugs of esuberaprost and pharmaceutical compositions thereof, as well as methods of making and methods of using these prodrugs.
US11560362B2	Dibutylfluorene derivative and application thereof as photoinitiator The present invention provides a dibutylfluorenyl derivative, an application of same as a photoinitiator, and a preparation method therefor. The present invention provides a photocuring composition including the compound and a photocuring method using the composition.
US11560356B2	Compounds and compositions for the treatment of cancer The present disclosure provides compounds, pharmaceutical compositions, and methods for the treatment of cancer and fibrosis. The disclosed pharmaceutical compositions may include one or more pyrazolyl-containing compounds, or a derivative thereof.
US11560355B2	Onium salt, chemically amplified resist composition, and patterning process A novel onium salt of formula (1) and a chemically amplified resist composition comprising the same as a PAG are provided. When processed by photolithography using KrF or ArF excimer laser, EB or EUV, the resist composition has a high sensitivity and reduced acid diffusion and is improved in exposure latitude, MEF, and LWR.
US11560352B2	P62-ZZ small molecule modulators A compound, or a pharmaceutically acceptable salt thereof, having a formula I of: wherein Ar is an arylene or heteroarylene; R1 has a structure of: wherein W is an alkanediyl, alkenediyl, a carbonyl, or a combination thereof; X is —NR5—, wherein R5 is H or an alkyl, or —O—; and Y is optionally-substituted cycloalkyl, optionally-substituted cycloalkyl-substituted alkyl, optionally-substituted heterocycloalkyl, or optionally-substituted heterocycloalkyl-substituted alkyl; each R2 is the same or different and has a structure of: wherein Z is —NR6—, wherein R6 is H or an alkyl, —O—, —S—, or —CH2—; Z1 is (—CH2-)m wherein m is 0 to 5, or an alkenediyl having 2 to 6 carbon atoms; Cy is a 3-8-membered cycloalkyl, heterocycloalkyl, aryl or heteroaryl ring; and each R4 is the same or different and is selected from hydroxy, halogen, substituted or unsubstituted alkoxy, substituted or unsubstituted alkyl, or amino; and c is 0 to 5; and each R3 is the same or different and is selected from hydroxy, halogen, substituted or unsubstituted alkoxy, substituted or unsubstituted alkyl, amino, substituted or unsubstituted cycloalkyl, substituted or unsubstituted heterocycloalkyl, substituted or unsubstituted aryl, or a nitro, wherein a is 2 to 5, and b is 0 to 3.
US11560345B2	Fluoroethane production method and fluoroolefin production method Provided are a method for producing a fluoroethane, which is the desired product, with high selectivity; and a method for producing a fluoroolefin. The production method according to the present disclosure comprises obtaining a product comprising a fluoroethane represented by CX1X2FCX3X4X5 (wherein X1, X2, X3, X4, and X5 are the same or different and each represents a hydrogen atom, a fluorine atom, or a chlorine atom; and at least one of X1, X2, X3, X4, and X5 represents a hydrogen atom) from a fluoroethylene by a reaction in the presence of at least one catalyst in at least one reactor. The reaction is performed by introducing a starting material gas comprising the fluoroethylene into the reactor, and the water content in the starting material gas is 150 ppm by mass or less based on the total mass of the starting material gas.
US11560343B2	Process for capture of carbon dioxide from air and the direct conversion of carbon dioxide into fuels and chemicals The invention relates to a process, catalysts, materials for conversion of renewable electricity, air, and water to low or zero carbon fuels and chemicals by the direct capture of carbon dioxide from the atmosphere and the conversion of the carbon dioxide to fuels and chemicals using hydrogen produced by the electrolysis of water.
US11560340B2	Seed treatment methods and compositions Disclosed are methods of enhancing plant growth, comprising treating seed at least one month prior to planting with an effective amount of a plant signal molecule, wherein upon harvesting the plant exhibits at least one of increased plant yield measured in terms of bushels/acre, increased root number, increased root length, increased root mass, increased root volume and increased leaf area, compared to plants harvested from untreated seed, or compared to plants harvested from seed treated with the signal molecule just prior to or within a week or less of planting.
US11560337B2	Additive for hydraulic binder useful to prevent the formation of rust-colored stains at the surface of hydraulic compositions A method for preventing formation of rust-colored stains on the surface of a hydraulic composition includes mixing the hydraulic composition with an additive for hydraulic binder including at least a dialkanolamine including from 2 to 8 carbon atoms, and at least a polyol preferably chosen from a diol, a triol, a tetraol and mixtures thereof. Other uses include a grinding aid for hydraulic binder precursor, and/or improving the compressive strength of a set hydraulic composition.
US11560335B2	Molded body formed from curable composition To provide a molded body which has high strength, high ductility, and excellent dimensional stability while maintaining incombustibility and fire resistance.A molded body formed from a curable composition containing (A) at least one aluminosilicate source, (B) an alkali metal hydroxide, (C) a calcium ion source, and (D) an alkali resistant fiber, wherein the aluminosilicate source (A) has an SiO2 content of 50% by mass or more based on a total mass of the aluminosilicate source (A), an amorphous ratio of 50% by mass or higher, and an average particle diameter of 50 μm or smaller, and comprises an aluminosilicate source having an average particle diameter of 10 μm or smaller in an amount of 30% by mass or more based on the total mass of the aluminosilicate source (A).
US11560334B2	Concrete repair coating A concrete and asphalt repair coating formulation includes a cement component and an aggregate component. The cement component includes a calcium sulfoaluminate cement and a Portland cement. The aggregate component includes coarse aggregates between 125-500 microns in diameter and fine aggregates between 5-62.5 microns in diameter.
US11560332B2	Glass-based articles with engineered stress profiles and methods of manufacture Strengthened glass-based substrates having a first outer region compressive stress and a first side having first coating thereon are disclosed. The first coating comprising a material selected to have a first coating Young's modulus value, a first coating thickness, and a first coating stress that is either neutral or compressive, such that the absolute value of first outer region compressive stress is greater than the absolute value of the first coating stress. Methods of making glass-based articles are provided, and glass-based articles having coatings that provide different strength values and/or reliability on different sides of the glass-based articles are also disclosed.
US11560331B2	Coated glass article containing a semi-interpenetrating network A coated glass substrate and a method of making the glass substrate is disclosed. The method comprises the following: providing a coating formulation on a glass substrate wherein the coating formulation comprises at least one polymerizable compound, a glass frit, and a non-crosslinked polymer and heating the coating formulation on the glass substrate. The coated glass substrate includes a coating provided on a surface of a glass substrate wherein the coating comprises a semi-interpenetrating polymer network including a non-crosslinked polymer and a glass frit. The coating exhibits a stud pull of about 275 psi or more.
US11560323B2	Compositions of dry acid polymers and uses thereof The present embodiments generally relate to the use of one or more polymers, e.g., one or more dry acid polymers and/or one or more dry acid polymers with salt, as flocculants, generally for treating tailings, e.g., oil sands tailings, in need of solid-liquid separation, e.g., in order to efficiently recycle water and/or to reduce the volume of tailings which may be transferred to a tailings pond and/or a dedicated disposal area.
US11560318B2	Facile, low-energy routes for the production of hydrated calcium and magnesium salts from alkaline industrial wastes Divalent ions are extracted from solids by leaching to form a divalent ion-containing solution. The divalent ion-containing solution is subjected to concentration to form a concentrated divalent ion-containing solution. Precipitation of a divalent ion hydroxide salt is induced from the concentrated divalent ion-containing solution. In other cases, the concentrated divalent ion-containing solution is exposed to carbon dioxide to induce precipitation of a divalent ion carbonate salt.
US11560313B2	Graphene nanoribbons, graphene nanoplatelets and mixtures thereof and methods of synthesis Provided herein are graphene nanoribbons with high structural uniformity and low levels of impurities and methods of synthesis thereof. Also provided herein are graphene nanoplatelets of superior structural uniformity and low levels of impurities and methods of synthesis thereof. Further provided herein are mixtures of graphene nanoribbons and graphene nanoplatelets of good structural uniformity and low levels of impurities and methods of synthesis thereof. The method includes, for example, the steps of depositing catalyst on a constantly moving substrate, forming carbon nanotubes on the substrate, separating carbon nanotubes from the substrate, collecting the carbon nanotubes from the surface where the substrate moves continuously and sequentially through the depositing, forming, separating and collecting steps. Further processing steps convert the synthesized carbon nanotubes to graphene nanoribbons, graphene nanoplatelets and mixtures thereof.
US11560307B2	CO2 hydrogenation in reverse flow reactors Systems and methods are provided for hydrogenation of CO2 in a reverse flow reactor environment via a reverse water gas shift reaction. A reverse flow reactor environment is suitable for performing endothermic reactions at high temperatures, where a reactant flow is passed into the reactor in a first portion of the cycle in a first flow direction while a combustion or heating flow is passed into the reactor during a second portion of the reaction cycle from the opposite direction. This can allow for efficient heating of surfaces within the reactor to provide heat for the endothermic reverse water gas shift reaction while reducing or minimizing incorporation of combustion products into the desired reaction products.
US11560306B2	Method for producing ammonia The invention relates to a method for producing ammonia (1), wherein a carbon-containing energy carrier flow (2) and an oxygen flow (3) from an oxygen-producing assembly (4) are fed to a synthesis gas reactor assembly (5) for obtaining a synthesis gas flow (6) with hydrogen and carbon oxides, wherein the synthesis gas flow (6) is fed to an adsorption device (7) for separating the synthesis gas flow (6) into a hydrogen flow (8), which comprises hydrogen, and a purge flow (9), and wherein the hydrogen flow (8) and a nitrogen flow (10) are fed to an ammonia reactor assembly (11) and converted into ammonia (1) there. The method is characterized in that the purge flow (9) is fed to a recovery device (12), which obtains a hydrogen-containing recovery flow (13) from the purge flow (9) and discharges a waste gas flow (14) therefrom, and that the hydrogen of the recovery flow (13) is at least partly fed to the ammonia reactor assembly (11) for conversion into ammonia (1). The invention also relates to a corresponding system for the production of ammonia (1).
US11560304B2	Surface bio-functionalization method A method for functionalizing a surface of a dielectric plate that is transparent to visible light—to be able to examine the dielectric plate using optical microscopy—includes depositing a negative film on the dielectric slide. The negative film comprises a polymerizable composition that polymerizes when exposed to an electron beam. The polymerizable composition is polymerized—by exposing the negative film to the electronic beam—at a set of points representing a preset pattern. Non-polymerized portions of the polymerizable composition are dissolved—to develop the negative film—forming a set of pads of polymerized portions of the polymerizable composition. Each pad corresponds to one point of the preset pattern. A metal film is disposed on the negative film, and the developed negative film is dissolved to define holes through the metal film. Each of the holes corresponds to a base of one pad of the set of pads.
US11560301B2	Equine saddle pad display system A saddle pad display system, especially for equine use wherein a strap loop is mounted on the pad horizontally and the display is mounted via a pair of vertical loops. This system makes it easier to add and remove the display quickly and efficiently, ensuring repetitive results. This is especially useful for a competitor or exhibitor display number.
US11560299B2	Auto-water shut-off for an external door water dispenser A refrigerator including a refrigerated compartment and a door to open and close at least a portion of the refrigerated compartment. A dispenser unit is positioned on the door that is configured to dispense content into a receptacle. The dispenser unit includes a receptacle support, a dispensing system, a sensor system with at least a first sensor and a second sensor. A control unit electrically coupled to the dispensing system and sensor system. The dispensing system is configured to operate the first sensor to determine the receptacle height and the second sensor to determine the liquid height within the receptacle. The control unit determines when to stop filling the receptacle based on the two measurements. A method for detecting when to shut off the dispensing unit when dispensing liquid into a receptacle.
US11560297B2	Lifting system with indoor positioning system and method therefor The present invention relates to a lifting system and method for lifting a vehicle, wherein the lifting system including one or more lifting devices and: a frame with a carrier configured for carrying the vehicle; a drive for driving the carrier in at least one of the ascent or descent of the carrier; and a controller including an indoor positioning system with a transponder, wherein the transponder is provided on or at the carrier such that the controller determines the location and the height of the carrier in at least one of the ascent or descent of the carrier.
US11560294B2	Pulley with secured opening The tandem pulley comprises a pair of sheaves mounted in line between first and second flanges. A gate is fitted rotating with respect to the first flange between closed and open positions. The gate comes into contact with the second flange in the closed position to close a housing. The clamp is movable in rotation on the gate between a locking position locking the gate in the closed position and an unlocking position. The clamp has a prong pressing on the first flange and the gate in the locking position. The clamp has an actuating area separated from the first flange by the gate. Rotation of the actuating area from the locking position to the unlocking position corresponds to a movement of the actuating area away from the second flange. Rotation of the actuating area results in pivoting of the prong.
US11560291B2	Elevator arrangement to open the roof of an elevator car The invention relates to an elevator arrangement comprising an elevator with a control system, and an inspection or maintenance mode, which elevator further comprises an elevator car arranged to run up and down in an elevator shaft along its guide rails, and which elevator car is equipped with a roof and a car operating panel. The arrangement comprises actuating means to open the roof of the elevator car, which actuating means are operatively connected to the car operating panel of the elevator.
US11560287B2	Reel system and method A reel system that includes a drum that receives a coil of flexible pipe. A first flange that removably couples to a first side of the drum. A second flange that removably couples to a second side of the drum. The first flange and the second flange secure the coil of flexible pipe to the drum.
US11560286B2	Sheet folding device and sheet post-processing apparatus including the same A sheet folding device includes a folding rollers pair, a folding blade and a sheet guide. The folding rollers pair causes a sheet to pass through a first nip area to fold the sheet. The folding blade includes a blade portion and a pair of arm portions. The blade portion is selectively disposed in a folding position where the blade portion pushes a folded portion of the sheet into the first nip area and in a retracting position where the blade portion is retracted from the folding position. The pair of arm portions couples both end portions of the blade portion with the pivot shaft. The sheet guide can be passed between the pair of arm portions. Between the blade portion and the sheet guide, a retreating path in which a part of the sheet is retreated when the folded portion is pushed into the first nip area.
US11560284B2	Sheet discharge device and image forming apparatus A sheet discharge device includes a discharge member and a control part. When a sheet is discharged to a first offset position, the control part shifts the discharge member to a first reception position separated from a home position in a second direction by a second distance shorter than a first distance, and shifts the discharge member to a first discharge position separated from the first reception position in the first direction by the first distance after the sheet is received. When the sheet is discharged to a second offset position, the control part shifts the discharge member to a second reception position separated from the home position in the first direction by the second distance, and shifts the discharge member to a second discharge position separated from the second reception position in the second direction by the first distance after the sheet is received.
US11560279B2	Systems and methods for classifying sheets of a printing device A method comprises obtaining a training dataset, the training dataset comprising sheet passage interval information associated with conveyance of a plurality of sheets in a sheet conveyance path of a training sheet processing apparatus, at least a portion of the sheets of the plurality of sheets having a known sheet classification of a set of sheet classifications; obtaining sheet timing data associated with the classifying, the sheet timing data comprising sheet passage interval information associated with conveyance of a predetermined number of sheets in the sheet conveyance path of a deployed sheet processing apparatus; classifying, using a machine learning model and the training dataset and the sheet timing data, for each interval window of a plurality of different interval windows, a predetermined number of sheets in a sheet conveyance path of a deployed sheet processing apparatus as a particular classification of the set of sheet classifications; and adjusting, based on the classifying, one or more operational parameters of a deployed sheet processing apparatus.
US11560271B2	Liquid containers for electronic smoking device An electronic smoking device includes a liquid supply (34) and an atomizer in a housing. The liquid supply (34) includes at least two container members (34a, 34b) attachable to one another through a connection mechanism to form a liquid supply main body. Each of the container members (34a, 34b) may have an outlet (341a, 341b) sealed by a sealing member (342a, 342b) and a second end which is closed, and an aerosol channel (343a, 343b) formed between the container members.
US11560270B2	Spray can actuator An actuator for a spray can. The actuator includes a housing for attachment to an aerosol can covering a stem valve. A finger operating button structure is engaged with the housing for engaging the stem valve. A rotary two-way diverter valve is supported within the housing and rotatably engaged with the finger operating button structure. In a spray position/straw down, the two-way diverter valve directs spray through a first direct spray nozzle. In a second straw position/straw up, to make use of an adjustable straw, the diverter valve is rotated to engage a straw spray passage of the diverter valve in fluid communication with an adjustable rotary spray tip and engaged straw. By rotating the adjustable rotary spray tip to an aligned position, the tip substantially blocks the straw spray passage to provide a drip mode, where drops of fluid exit the straw. A flexible tip may optionally be provided on the straw to enable bending and retention of the flexible tip to a desired position.
US11560268B2	Device for packaging at least a first and a second fluid The invention relates to a device for packaging at least a first and a second fluid comprising an arrangement consisting of a first container for containing a first fluid and a second container for containing a second fluid, wherein the first container is substantially in the form of a tube, preferably in the form of a tube, the first end of which is provided with a dispenser and the second end of which is designed to attach said second container to this second end and thus close said second end of the first container, wherein the second container is substantially in the form of a tube, preferably in the form of a tube, the first end of which is designed to be attached to the second end of the first container, said first end of the second container being closed by means of a tearable wall, and the second end of which is closed by means of a movable wall, said movable wall being designed to be displaced in the direction of said tearable wall to open said tearable wall and thus allow the first and second fluid to mix with each other.
US11560267B2	Evacuated bottle system A cap assembly including a self-sealing membrane that overlaps an opening to an interior of a container. The cap assembly further includes a cap having a cover portion that includes an annular wall that defines a central opening, and at least one evacuating opening located radially outward of the central opening. The cover portion defines a gap above the self-sealing membrane. The gap is configured to allow the self-sealing membrane to be at least partially displaced from the opening to allow fluid communication between the interior of the container and an outside atmosphere when a suction is applied to the cap.
US11560266B1	Heterogeneous insulated bag for food delivery to end consumers A food delivery enclosure for delivering groceries includes a low insulation zone and a high insulation zone. The low insulation zone includes energy packs, such as chill packs or hot packs and food items suitable for contact with the energy packs. The high insulation zone is above the low insulation zone and includes food items that are not suitable for contact with the energy packs.
US11560265B2	Packing film with a top layer forming a predefined opening track The invention is directed to a packaging film (2) comprising: a top layer (4) with at least one aperture (4.1); a bottom layer (8) adhered to the top layer (4); a tear layer (6) adhered to the bottom layer (8) and extending along the at least one aperture (4.1) so that upon traction on the tear layer, said layer tears the bottom layer (8) through the aperture(s) (4.1). The tear layer (6) extends beyond the at least one aperture (4.1), between the top layer (4) and the bottom layer (8), preferably longitudinally in two opposite directions. The invention also relates to a condom wrapping with such a film and to the manufacturing method for such a film.
US11560261B2	Double-spout bottle cover and water bottle A double-spout bottle cover includes a cover body. A second water outlet is arranged at the upper end of the cover body. A flip cover is covered on the second water outlet. The cover head of the flip cover covers the second water outlet. A flip cover shaft of the flip cover is fixed on the cover body and is opposite to the second water outlet. The middle of the flip cover is a hollow area. The hollow area is provided with a first water outlet, and the surface of the first water outlet is flush with the surface of the flip cover. The bottom of the first water outlet is connected to a preset through hole on the cover body. The first water outlet is fixed on the cover body by a rotating shaft.
US11560260B2	Packaging container having a secure closure and retention elements A thermoformed packaging container includes a base section having a bottom surface, first and second inner and outer base side walls, and first and second inner and outer base end walls forming a chamber, with at least one outer base one side wall having a plurality of base indentations and protrusions formed therein. A cover section having a top surface, first and second cover side walls, and first and second cover end walls, the cover section adapted to cover the base section when in a closed state, with at least one of the cover side walls having a plurality of cover indentations and protrusions formed therein for engaging with the plurality of base indentations and protrusions. The container also includes a closure mechanism for securing the container in a closed position, wherein the closure mechanism is formed within at least one end wall of the base section and a corresponding end wall of the cover section.
US11560259B2	Liquid-dispensing container with multiple-position selector A liquid-dispensing container may include a vessel, lid body, valve assembly, selector and/or straw. The selector may be movable between a first position that allows fluid disposed within the container to be discharged through a straw, and a second position that allows fluid within the container to be discharged by inverting and/or squeezing the container. The selector may be movable into a closed position that restricts fluid from being discharged from the container. The selector may be movable into a detachment position that allows for detachment of the selector from a remainder of the container, disassembly of the valve assembly, or both.
US11560253B2	Roller assembly, package including the roller assembly and method of using the package A roller assembly includes at least one roller, an L-shaped board and at least one L-shaped fixing member. The L-shaped fixing member is fixed on the L-shaped board; and the roller is fixed and connected on the L-shaped board through the L-shaped fixing member. A package includes a box and the roller assembly. The box contains at least one hole and the roller protrudes from the hole. Further, the package is used as follows. The box is opened and the matter to be packaged is put into the box. Then the roller assembly is placed into the box, and the roller assembly is sandwiched between the box and the matter. Next, the roller(s) is aligned with the hole(s). Subsequently, the box and the matter are compressed to make the roller(s) protrude from the hole(s). Finally, the box are sealed from the bottom surface to complete the package.
US11560251B2	Shipping container and method of folding a shipping container A foldable container blank includes at four side walls, a top panel foldably connected to one of the side walls, a bottom panel foldably connected to one of the side walls, and at least one internal support structure that is connected to one of the side walls. Each internal support structure includes a first portion that is in adjacent relation with the top panel when the container is in a closed condition, and a second portion that is in adjacent relation with the first portion when the container is in a closed condition. In some embodiments, the foldable container blank is integrally formed. A method of forming the foldable container blank and a method of folding a container blank are also provided.
US11560249B2	Case unpacking system and method A product unpacking system includes a work surface at a first height and a product unloading position at a second height. An adjustable cutter is positioned adjacent to the work surface and configured to cut a plurality of sides of each case. A case movement device, such as a robot or manual mover, is configured to retrieve a case from a group of cases and move the case to the cutter to cut a plurality of sides of the case. The case movement device may then move the cut case to an unload position over a product container to allow products within the case to drop into the product container. A system of conveyors may be used to convey empty product containers toward the work surface and to convey filled product containers away from the work surface. The system may be automated to receive recipe information for each case to be unloaded and modify parameters of the system based on the case.
US11560247B2	Strapping tool A strapping tool is disclosed herein. In one or more embodiments, the strapping tool includes a motive power source and a sealing assembly. The sealing assembly includes a first punch and a die, the first punch and die configured to crimp or cut a notch in a strapping seal member and/or a piece of strapping so as to secure the piece of strapping around a package or bundle of items.
US11560246B2	Strapping apparatus A strapping apparatus for strapping articles with a strapping band having a tensioning device for imparting a band tension to a loop of the strapping band, the tensioning device including a driveable tensioning element provided for engaging the strapping band to impart a band tension. The strapping apparatus including a connecting device for generating a permanent connection, in particular a welded connection, at two regions, situated one above the other, of the loop of the strapping band. The strapping apparatus is configured to achieve the release of the tensioning element from the strapping band reliably to avoid or reduce adverse characteristics attributed to the release of the tensioning device from the band.
US11560241B2	Support bracket for holding interior components of a vehicle A support bracket for holding interior components of a vehicle includes a base plate and an add-on module, which are engageable with each other to facilitate replacement and maintenance.
US11560238B2	Providing a load from a motor to inhibit further rotation of a propeller of an aerial vehicle while in flight A technique for operating an aerial vehicle involves enabling a vertical takeoff and landing (VTOL) propeller of the aerial vehicle to rotate freely. The VTOL propeller is coupled with a VTOL motor (e.g., a 3-phase brushless DC motor). The technique further involves detecting when the VTOL propeller rotates to a predefined position relative to a direction of flight for the aerial vehicle (e.g., when blades of the VTOL propeller extend along an axis that is parallel to the direction of flight). The technique further involves, in response to detecting that the VTOL propeller has rotated to the predefined position, providing a load from the VTOL motor that inhibits further rotation of the VTOL propeller. Accordingly, while the aerial vehicle is in fixed wing horizontal flight, the controller is able to align the VTOL propeller in the direction of horizontal flight to minimize drag from the VTOL propeller.
US11560236B2	System and method for controlling a takeoff thrust The present disclosure provides systems and methods for controlling thrust produced at takeoff by at least one engine (114, 116) of an aircraft (100). At least one input signal comprising input data indicative of a speed of the aircraft is received (202). The speed of the aircraft is compared to a first pre-determined threshold. Responsive to determining that the speed is below the first threshold, a thrust limit for the at least one engine is determined (204) from the input data and output to the at least one engine a thrust limitation signal for causing the thrust to be limited according to the thrust limit (210).
US11560235B2	Aircraft propulsion unit An aircraft propulsion unit includes an electric motor, at least one accessory unit used for operating the electric motor, an inverter module, the inverter module including a plurality of inverters for powering the electric motor and the at least one accessory unit, and a cooling system coupled to the electric motor and the inverter module, the cooling system comprising a coolant path for circulating a coolant through or adjacent to the electric motor and the at least one accessory unit.
US11560230B2	Removable cargo floor systems and methods for cargo aircraft Systems and methods for removeably adding a cargo bay floor to the interior cargo bay of cargo aircraft bay are disclosed. The system includes a rail disposed in a cargo bay of a cargo aircraft with the rail extending longitudinally along both a length of a forward portion and an aft portion of the fuselage. The system includes a cargo floor segment configured to be removeably attached to the rail. When attached, the cargo floor segment can transform between a first arrangement with the cargo floor segment translatable along the rail, and a second arrangement with the cargo floor segment fixedly secured to a location along the rail. The cargo floor segment is configured to, when secured to the rail, define a section of a floor of the cargo bay of the cargo aircraft. Multiple floor segments can be used together to form a continuous floor for the aircraft.
US11560229B2	High-efficiency method using unmanned aerial vehicles for firefighting A method of fire-fighting is provided based on unmanned aerial vehicles “UAV(s)” launched from transporter aircrafts to deliver water or fire-retardants or any other fire-fighting materials to a location selected by the fire-fighting personnel. A capability of putting-off high intensity forest fires is provided that stems from the precision and the quantity of material that can be delivered per unit surface per unit time. After releasing the fire-fighting material(s), the UAV reaches a safe altitude from which it flies on autopilot to intercept and then proceed on a pre-programmed route to land per pre-programmed instructions on an airfield from which fire-fighting transporter(s) operate, allowing a high efficiency along the line, from loading the transporter airplanes to maximizing the quantity of material that reach the target, to minimizing the remote-pilot time and up to the recovery system that minimizes the recovery cost and it maximizes UAVs' utilization by a quick turnaround.
US11560228B2	Restrain and release mechanism for an externally airborne load A restrain and release mechanism for an externally airborne load, includes at least one stiff support for suspending the load and an elastically deformable adaptive member designed to maintain the load at pressure contact against the support. The adaptive member is a three-dimensional monolithic metallic body obtained using an additive manufacturing method and having a flexural orthotropic behaviour.
US11560225B2	Hover and thrust control assembly for dual-mode aircraft A combined hover and forward thrust control assembly for a dual-mode aircraft includes a support structure attached to an aircraft frame of an aircraft having at least a vertical thrust propulsor and at least a forward thrust propulsor a throttle lever rotatably mounted to the support structure, wherein rotating the throttle lever in a first direction increases power to at least a vertical thrust propulsor and rotating the throttle lever in a second direction decreases power to at least a vertical thrust propulsor and a linear thrust control mounted on the throttle lever, wherein movement of the linear thrust control in a first direction increases forward thrust of at least a forward thrust propulsor, and movement of the linear thrust control in a second direction decreases forward thrust of the forward thrust propulsor.
US11560223B2	Flight vehicle Provided is a flight vehicle and in particular a flight vehicle in which a main module equipped with a device capable of carrying cargo, photographing, etc. may freely switch directions during flight while applying a posture independent of a thrust module because the thrust module is configured to freely perform roll and pitch motions with respect to the main module.
US11560219B2	Aircraft landing gear uplock system An uplock for use with an aircraft landing gear is disclosed having a hook configured to engage a capture pin mounted on the landing gear. The hook is mounted for movement between a closed and locked position and an open and unlocked position. A proximity detector directly detects whether the pin is “up”. An uplock hook sensor detects when the hook is in the closed and locked position. The outputs of the proximity detector and the uplock hook sensor may be used to indicate the “up and locked” condition, i.e., landing gear up, and/or to indicate a fault. Such outputs may be provided by an associated device of an avionics system.
US11560218B2	Electromechanical actuator disconnect A landing gear includes a strut and an electromechanical actuator coupled to the strut. The electromechanical actuator includes a motor assembly, a ball nut, a split ball screw disposed between the motor assembly and the ball nut, and an actuator release assembly coupled to the split ball screw.
US11560213B2	Devices and methods to structurally close and seal openings in an aircraft wing fuel tank Closure devices and methods are provided for closing a stringer penetration space defined between a stringer and a wing rib of an aircraft wing section. According to certain embodiments, the closure devices will integrally include a forward face plate positioned in covering relationship to at least a portion of the stringer penetration space, and a rearwardly projecting attachment arm rigidly adapted for rigid attachment to the stringer so as to positionally fix the forward face plate relative to the stringer penetration space.
US11560210B2	Aerospace balloon system and method of operation A balloon system including a balloon, and optionally including a payload and/or a safety module. A balloon, preferably including a balloon envelope and one or more passive vents, and optionally including one or more active valves. A method of balloon system operation, preferably including maintaining a zero-pressure balloon condition and sealing balloon vents, and optionally including ascending, descending, and/or otherwise operating the balloon system in flight.
US11560208B2	Harness spreader bar for wind sports A spreader bar for a wind sport harness, with a front member having at least one release latch on one end. A structural side member is releasably securable to the release latch. A bracket for receiving the side member is configured to releasably secure the side member. The length of the side member extending through the bracket is adjustable. Closing the at least one release latch can create a unitary mechanical connection around a user.
US11560207B2	Mask for underwater use, in particular of granfacial type with assisted breathing A diving mask includes a transparent visor, a frame, a gasket to guarantee the watertight seal and appropriate belts for fitting the mask, a breathing tube associated with the facial part is fitted onto the upper part of the mask and which enables the flow of air to enter into the compartment between the frame and the visor. The path of air in the inhalation phase and in the exhalation phase both in the mask and tube are different from each other. The tube is made with separate ducts for inhalation and exhalation and the inside of the mask is made with two compartments, one upper front and one lower oronasal separated by a wall. The path provides that inhalation air is introduced by the tube into the frontal compartment and then into the oronasal one and air exhaled from the oronasal compartment travels up to the tube.
US11560206B1	Stern light The present disclosure is directed to a stern light for illuminating a watercraft without visually impairing a passenger of the watercraft. The stern light includes a flexible pole with a hollow interior for housing wires. The wires are connected to a watercraft at one end of the pole and to a light source at another end of the pole. The light source, which may be an LED light source, is covered by a globe that at least partially refracts light. When powered, the stern light produces light capable of providing visibility of the watercraft for at least two nautical miles while also avoiding the visual impairment of watercraft passengers. Pole flexibility allows operation of the stern light during watercraft motion and in areas with potential obstructions, such as low-hanging branches.
US11560205B2	Lifting system for a floating vessel A lifting system includes elevator towers constructed on a deck of a floating vessel, tracks constructed above the deck of the floating vessel, a traveling cradle beam, and one or more cranes supported by the traveling cradle beam. The traveling cradle beam can be in a first configuration in which the traveling cradle beam is coupled to the elevator towers and can move along the elevator towers past the tracks, and in a second configuration in which the traveling cradle beam is decoupled from the elevator towers and can skid over the tracks. The lifting system can be constructed in stages, and the portion of the lifting system constructed in the initial stages can be used to continue constructing the lifting system in the remaining stages. The lifting system can be used for transporting equipment on the floating vessel.
US11560204B2	Techniques for providing variable buoyancy to a device A variable buoyancy device has an inner region and an outer cavity. The outer cavity extends at least partially around the inner region and is adapted to contain fluids, such as a liquid and a gas, the relative proportions of which can be varied to vary buoyancy. The inner region provides an advantageous location for equipment, while the outer cavity provides a significant volume for achieving a wide range of buoyancy adjustments.
US11560197B2	Electric assist bicycle An electric assist bicycle includes an electric motor that generates an assistance force to assist a human force of a rider, a handle to be gripped by the rider with a hand to steer the electric assist bicycle, a manipulation device provided on the handle and including an operation switch that receives a manipulation from the rider and an alternate switch that receives a manipulation from the rider to change functions to be assigned to the operation switch, and a control circuit that performs a control to alter an operation to be executed by the electric assist bicycle depending on whether the rider manipulates the operation switch in a state of keeping the alternate switch manipulated or the rider manipulates the operation switch in a state of not manipulating the alternate switch.
US11560195B2	Profiles for bicycle components A bicycle includes a frame having cross sectional profiles. The profiles are designed according to certain criteria to enhance bicycle performance. The profiles for multiple frame members may each fall within a range for each of aspect ratio, circumference, drag coefficient, first moment of inertia and/or second moment of inertia.
US11560190B2	Track chain components with hardface overlay A steel track chain component, such as a track bushing, may be formed with a carburized portion, a hardface portion, and a core portion. The core portion may be softer than the carburized portion, which in turn, may be softer than the hardface portion. This configuration of the various portions of the component may allow for relatively high wear resistance of the component, as well as toughness. The core portion may be mostly ferrite crystal structure, while the carburized portion and the hardface portions may include martensitic and/or austenitic crystal structure. The carburized portion may be formed by carburizing the track chain component in a heated and carbon rich environment. The hardface portion may be formed by welding a hardface alloy over at least a portion of the carburized portion.
US11560186B2	Load sensing pin box A pin box assembly having a column connected to a skid plate with an upper and lower surface. A kingpin is affixed to and extends from the skid plate. The skid plate is restrained from movement with respect to the column, and the column is for being connected to a towable RV. A strain gauge may be mounted to an upper surface of the skid plate. As an alternative to mounting the strain gauge to the skid plate, the strain gauge may be mounted to the column of the pin box. The strain gauges in the aforementioned locations measure strain as the weight of a towable RV is placed upon a fifth wheel hitch.
US11560185B2	System and method for controlling deployment of a vehicle air dam A system and method for controlling deployment of a vehicle air dam that include receiving vehicle data associated with a vehicle operating condition. The system and method also include analyzing the vehicle data to determine if an elevated engine load condition is present to implement a normal air dam deployment mode or a prohibitive air dam deployment mode. The system and method further include controlling an actuator associated with the vehicle air dam to deploy or retract the vehicle air dam based on the implementation of the normal air dam deployment mode or the prohibitive air dam deployment mode.
US11560183B2	Truck bedslide assembly A bedslide assembly for use on a deck bed of a pickup truck is provided. An illustrative example of the bedslide assembly includes a bottom frame assembly, middle frame assembly, and top frame assembly. The bottom frame assembly includes a first latch bracket and a second latch bracket. The middle frame assembly includes a first latch assembly and a second latch assembly. The first latch assembly includes a hook. The second latch assembly also includes a hook. The top frame assembly includes an end plate. The hook of the first latch assembly is selectively engageable with the first latch bracket of the bottom frame assembly. The hook of the second latch assembly is selectively engageable with the end plate of the top frame assembly.
US11560181B2	Grounds maintenance vehicle with flip-up implement drive cover A stand-up grounds maintenance vehicle including a chassis, a control tower, an implement, and a cover. The chassis is supported upon a ground surface by a plurality of ground-engaging members and extends along a longitudinal axis between a front end and a rear end. The control tower is coupled to the chassis proximate the rear end. The implement is attached to the chassis and is positioned at least partially forward of the control tower. The implement includes an implement drive. The cover extends over the implement drive and is pivotally coupled to the chassis.
US11560180B2	Vehicle component with multi-hollow beam A rocker component for a vehicle includes a reinforcement beam having a metal sheet that is shaped with a plurality of elongated bends extending in parallel along a length of the reinforcement beam that together form a cross-sectional shape extending continuously along the length of the reinforcement beam. The cross-sectional shape of reinforcement beam includes a beam portion and a flange portion integrally extending from the beam portion. The beam portion has a multi-hollow shape that encloses a plurality of hollow cavities that extend longitudinally between openings at opposing ends of the reinforcement beam. The flange portion integrally extends from the beam portion and includes an edge of the metal sheet. The flange portion is configured to attach to the vehicle for supporting the rocker component along an outboard side region of the vehicle.
US11560179B2	Collision energy absorbing apparatus The present disclosure provides a collision energy absorbing apparatus capable of suppressing a peak load at the initial stage of a collision and a load drop immediately after it. The collision energy absorbing apparatus is an apparatus that absorbs collision energy, the apparatus being mounted on a vehicle and including a pressure member, an absorbing member, and a guide part that guides, a moving direction of the pressure member, in which a hole through which the pressure member guided and moved by the guide part enters is formed in the absorbing member, and in an event of a collision, the pressure member is guided by the guide part and a tip part of the pressure member enters the hole formed in the absorbing member while shearing an inner wall of the hole, to thereby absorb collision energy.
US11560178B2	Apparatus and method for displaying rear image of vehicle Disclosed are an apparatus and method for displaying a rear image of a vehicle. The apparatus for displaying a rear image of a vehicle includes a rear camera configured to capture a rear image of the vehicle, a steering angle sensor configured to sense a steering angle of a steering wheel, a display unit, and an image processing unit configured to convert the rear image captured by the rear camera when the vehicle moves backward into an image in a direction where the vehicle is to move backward according to the steering angle of the steering wheel that is sensed by the steering angle sensor, and display the converted image in the direction where the vehicle is to move backward through the display unit.
US11560174B2	Automatic steering control device An automatic steering control device includes a forward recognition device, a traveling state detector, a lateral positional deviation calculator, a steering angle controller. The lateral positional deviation calculator calculates a first lateral positional deviation that is the lateral positional deviation ahead of the vehicle by a first distance, and a second lateral positional deviation that is the lateral positional deviation ahead of the vehicle by a second distance larger than the first distance. The steering angle controller performs first control on the steering angle so that an absolute value of the first lateral positional deviation decreases, and second control on the steering angle based on the second lateral positional deviation so that a difference between a change amount of the steering angle in the first control and a change amount of an actual steered angle that is a steered angle of wheels of the vehicle decreases.
US11560172B2	Motor control device A motor control device drives a motor based on a vehicle signal including drive assist information and performs vehicle control. The motor control device includes: a first controller and a second controller that perform a calculation operation concerning drive control over the motor. A first microcomputer corresponds to a calculation portion of the first controller. A second microcomputer corresponds to a calculation portion of the second controller. The first microcomputer and the second microcomputer mutually transmit and receive operation results by inter-microcomputer communication, or the first microcomputer unilaterally transmits an operation result from the first microcomputer by the inter-microcomputer communication. The first microcomputer and the second microcomputer synchronize timings to start and end control by performing at least one of three types of arbitration processes including: an AND-start arbitration process; an OR-start arbitration process; and a forced arbitration process.
US11560169B2	Retractable steering column system and method A steering column system includes a steering column shaft. Also included is a steering input device coupled to the steering column shaft. Further included is an energy absorbing mechanism operatively engaged with at least one of the steering column shaft and the steering input device. Yet further included is a column adjustment assembly configured to translate the steering column shaft between a retracted position and a driving position. Also included is at least one signal indicating whether the steering column shaft is in the retracted position or the driving position, and when the steering column shaft is in the retracted position, directional control of a vehicle is automated and the energy absorbing mechanism is in a non-operational state, and when the steering column shaft is returned to the driving position as indicated by the at least one signal, the energy absorbing mechanism is in an operational state.
US11560168B2	Four position hand truck A hand truck includes a frame that is supported by main wheels and a handle having two side members. Two handle brackets are pivotably mounted on opposite sides of the frame. The handle brackets are arranged for rotation in relation to the frame around a handle rotation axis. The handle brackets slidably receive the side members of the handle so that the handle is able to slide between a first retracted position and a second extended positon. The handle is also able to rotate with the handle brackets between first and second rotational positions. A lock mechanism that is mechanically associated with the handle brackets and the handle is able to releasably lock the degree of extension of the handle in at least one position between the retracted and extended positions and is able to lock the rotational position of the handle in at least one rotational position.
US11560165B2	Apparatus and method for gathering data from sensors oriented at an oblique angle relative to a railway track A system and method for inspecting a railway track using sensors oriented at an oblique angle relative to a rail vehicle on which the system is traveling. The orientation of the sensors allows for different data to be gathered regarding a particular rail including rail design specifications (gathered based on manufacturer markings detected and analyzed by the system), rail seat abrasion values based on direct measurement of rails from the oblique angle, and other analysis of rail features including joint bars, rail welds, bond wires, rail holes, and broken rails. The use of an air blower, ducts, and one or more air distribution lids over the sensors helps remove debris from blocking the sensors and structured light generators.
US11560162B2	Railcar energy absorption system and related method for absorbing energy on a railcar An energy absorption system for a railcar having an elongated sill with front and rear stops defining a pocket therebetween. To facilitate use of known railcar structures, the energy absorption system can be used in combination with a railcar also having a sill with center stops disposed between the front and rear stops. A coupler having a head portion and a shank portion is arranged in operable combination with the energy absorption system. The energy absorption system also includes a first cushioning assembly positioned in the sill pocket. A first follower is urged toward and engageable with the front stops under the influence of the first cushioning assembly and is operably engageable with a free end of the shank portion of the coupler. A second cushioning assembly is positioned in generally axial alignment with first cushioning assembly. A second follower is positioned and normally urged by the energy absorption system toward and configured to engage with the center stops. An axially elongated yoke encompasses the first and second cushioning assemblies, terminates in an open forward end, and is coupled to the shank portion of the coupler. The first and second cushioning assemblies act in series relative to each other to absorb and cushion impact forces directed against them when the energy absorption system operates in a buff direction. Advantageously, the second follower acts in concert with the center stops and the second cushioning assembly to minimize excessive system cycles while better dissipating train action energy when the energy absorption system operates in a draft direction.
US11560155B2	Information processing device, information processing method, and system An information processing device includes a control unit configured to: acquire information on a destination of a user who uses a resting unit including equipment on which the user is able to sleep, information on an arrival time at the destination, and information on a place in which the user uses the resting unit; transmit a command to a traveling unit configured to be coupled to the resting unit and carry the resting unit such that the traveling unit is coupled to the resting unit and arrives at the destination at the arrival time; and transmit a command to a stimulation device configured to stimulate the user who is using the resting unit such that the stimulation device is activated before the traveling unit is coupled to the resting unit or before the traveling unit departs for the destination after being coupled to the resting unit.
US11560154B1	Autonomous vehicle remote teleoperations system A teleoperations system may be used to modify elements in the mapping data used by an autonomous vehicle to cause the autonomous vehicle to control its trajectory based on the modified elements. In addition, in some instances, a teleoperations system may be used to generate virtual paths of travel for an autonomous vehicle based upon teleoperations system virtual path suggestion inputs.
US11560153B2	Systems and methods for collision avoidance by autonomous vehicles Systems for collision avoidance by an autonomous vehicle include a navigational controller adapted to (i) control a driving path of the autonomous vehicle, (ii) process sensor signals from a first sensor system, and (iii) determine whether an object is present in the driving path of the autonomous vehicle based on the sensor signals from the first sensor system. The systems can also include a processor, operationally independent from the navigational controller, adapted to (a) process sensor signals from a second sensor system and (b) determine whether an object is present in the driving path of the autonomous vehicle based on the sensor signals from the second sensor system.
US11560146B2	Interpreting data of reinforcement learning agent controller The present disclosure describes systems and methods that include calculating, via a reinforcement learning agent (RLA) controller, a plurality of state-action values based on sensor data representing an observed state, wherein the RLA controller utilizes a deep neural network (DNN) and generating, via a fuzzy controller, a plurality of linear models mapping the plurality of state-action values to the sensor data.
US11560144B2	Drive safety forecast for future drives In non-limiting examples of the present disclosure, systems, methods and devices for surfacing drive safety notifications are provided. A personal driving pattern library comprising first data associated with a first user for a plurality of road sections included in a first route may be maintained. A global driving pattern library comprising second data associated with a plurality of users for the plurality of road sections included in the first route may be maintained. A determination may be made that the first user is going to travel the first route. A first drive safety score for the first user driving the first route may be calculated. A determination may be made that the first drive safety score is below a threshold value. A drive safety notification may be caused to be surfaced.
US11560142B2	Speed sensor including insulating inner and outer recesses A speed sensor for measuring a speed of an object moving relative to the speed sensor, including: a speed sensor housing for providing sliding and/or frictional and/or positively locking insertion into a fixed receptacle, wherein the speed sensor housing houses an injection molded part which is made of plastic and into which at least part of a speed sensor element is injected; wherein the injection molded part has at least one outer recess, on its outer circumferential surface facing an inner face of a wall of the speed sensor housing, wherein an empty outer chamber is formed between each boundary surface of an outer recess and the inner face of the wall of the speed sensor housing, and/or wherein at least one inner recess, which forms an empty inner chamber, is formed inside the injection molded part. Also described are a related driver assistance system and a motor vehicle.
US11560141B2	Vehicle A vehicle includes a first rotary electric machine, a second rotary electric machine, and a control circuit. When the control circuit determines that a failure has occurred in the first rotary electric machine, the control circuit places the first rotary electric machine and a first transmission path as a power transmission path of the vehicle in the disconnection state, and places the second rotary electric machine and the first transmission path in the connection state. Further, when the control circuit determines that a failure has occurred in the second rotary electric machine, the control circuit places the first rotary electric machine and a first transmission path in the connection state, and place the second rotary electric machine and the first transmission path in the disconnection state.
US11560140B2	Switchable powertrain A switchable powertrain comprises at least four points of freedom. The switchable powertrain comprises a main gear set configured for gear ratio selection, the main gear set comprising main gears coupled to a main shaft and second gears coupled to a second shaft. An adapter comprises a first selective coupling configured to selectively couple to the main shaft, and a second selective coupling configured to selectively couple to the second shaft. A first torque source and a clutch are configured for selectively coupling or decoupling first torque to the main shaft. A second torque source is configured for selectively outputting second torque to the first selective coupling or to the second selective coupling.
US11560134B2	Default charging of automotive battery while parked A vehicle control system may, during a deactivated state of the vehicle, generate a wake up signal, and responsive to a current or voltage associated with the wake up signal being outside a predetermined range, activate an ignition relay of the vehicle for a predefined period of time. The vehicle control system may further, responsive to a request to activate the vehicle, activate the ignition relay.
US11560132B2	Adaptive refueling for evaporative emission control Methods and systems are provided for an evaporative emission control system. In one example, a method may include halting a dispensing of fuel to a fuel tank during a refueling event by increasing a backpressure in the fuel tank. The halt to fuel dispensing may be executed based on one or more of an upcoming fuel vapor canister purge event and an estimated fuel vapor canister loading capacity to determine a predicted canister breakthrough. The predicted canister breakthrough may be compared to a threshold to regulate a refueling volume.
US11560131B2	Lane prediction and smoothing for extended motion planning horizon Embodiments of the present disclosure are directed to lane marker prediction for occluded lane markers. Image data from one or more sensors of a vehicle is received by a processor of a control system. The image data includes a roadway from a route being navigated by the vehicle and lane marker information. If there are not enough lane markers captured in the lane marker information to produce a threshold look-ahead horizon of the roadway ahead of the vehicle, a longest lane marker ahead of the vehicle from the lane marker information is selected. A curvature tangent to the longest lane marker is computed and predictive lane markers are generated based on the curvature tangent. The vehicle is steered based on the predictive lane markers ahead of the vehicle generated from the curvature tangent.
US11560130B2	Control allocation for vehicle torque Methods and systems are provided for using the weights of cost functions to improve linear-program-based vehicle driveline architectures and systems. In some embodiments, the methods and systems may include establishing values for driveline controls of a linear program based on driveline requests of the linear program. The values of the driveline controls, which may be used to adjust driveline actuators, may be established based on values of a plurality of weights of a cost function of the linear program, the weights respectively corresponding with the plurality of driveline requests.
US11560128B2	Electronic brake system The present disclosure relates to a control method of a brake system including a reservoir in which oil is stored, wherein the control method includes detecting a first level of a liquid level of oil stored in the reservoir, detecting a second level of the liquid level of oil stored in the reservoir, determining a decrease trend of an oil amount stored in the reservoir based on a time point when the first level is detected and a time point when the second level is detected, and limiting at least one additional function based on the decrease trend of the oil amount.
US11560116B2	Vehicle passenger restraint system comprising an airbag module A vehicle occupant restraint system comprises an airbag module (12) which includes an airbag (16) as well as an inflator (18) which upon activation supplies filling gas for the airbag (16). The airbag (16) is folded prior to activation into an airbag package (14) so that a main package (48) which contains a restraint part (52) of the airbag (16) constituting a major part of the airbag volume as well as a connecting portion (50) is formed which comprises a neck (54) of the airbag (16) connecting the restraint part (52) to the inflator (18), wherein the restraint part (52) is folded differently from the neck (54).
US11560114B2	Airbag apparatus Disclosed herein is an airbag apparatus that includes a pair of main cushions installed to respective left and right sides of a seat back and deployed forward when gas is delivered to an internal filling chamber, to restrain a passenger from sides, and a pair of auxiliary cushions coupled to respective front ends of the main cushions while in communication with the main cushions and deployed laterally at one ends thereof to restrain the passenger from a front.
US11560111B2	All TPO airbag assemblies An all thermoplastic olefin (TPO) airbag system for an automotive vehicle including a TPO airbag module housing coupled with a TPO airbag cover or chute, the system being particularly suitable as a front airbag system, and method of making the same. The airbag module housing may couple with the chute through a plurality of projections and windows, or through bolts.
US11560110B2	Collision detecting device A collision detection unit corrects a threshold value to a larger value, which a collision check unit uses to compare an output value of a collision detection unit, in case of a rough road surface than in case of a flat road surface. Thus, it becomes possible to suppress erroneous detection on the rough road surface while detecting a collision sensitively on a flat road surface. The rough road is detected by a vibration detection unit provided in a tire side device.
US11560106B2	Control device for vehicle-mounted apparatus A control device for a vehicle-mounted apparatus, the control device includes: a second CPU state judging section provided to the first CPU, and configured to judge a state of the second CPU based on a state of the inter-CPU communication and a voltage value of the electric power supplied from the first electric power supply section, or the second reset signal; and a first CPU state judging section provided to the second CPU, and configured to judge a state of the first CPU based on the state of the inter-CPU communication and a voltage value of the electric power supplied from the second electric power supply section, or the first reset signal.
US11560105B2	Undercover for vehicles having high elasticity and rigidity and method for manufacturing the same Disclosed are an undercover for vehicles with high elasticity and rigidity and a method of manufacturing the same. The undercover for vehicles with high elasticity and rigidity may include a needle-punched nonwoven fabric having a multi-layer structure of felt layers including a first PET fiber and a low-melting-point PET fiber, and each of the felt layers may have improved tensile strength and have optimized fiber alignment, to thereby improve the binding between fibers, mechanical rigidity and elasticity, as well as to reduce the weight of components, improve durability and secure harmlessness and inline workability.
US11560103B2	Component with integrated sensor chip A vehicle trim assembly includes a first trim component having an interior facing surface and an exterior facing surface, the first trim component including an extended portion, a second trim component including an edge defining a groove configured to engage with the extended portion of the first trim component, and a single chip sensor overmolded with the second trim component such that the single chip sensor is integrated into the second trim component. The single chip sensor is formed with the second trim component in a multi-shot injection molding process.
US11560102B2	Vehicle with speaker for outputting virtual engine sound and controlling method thereof A vehicle and a controlling method of the same include a speaker outputting virtual engine sound integrated with a head lamp. The vehicle includes the head lamp; a head lamp case in which the head lamp is provided; and a speaker for outputting a virtual engine sound, and provided inside the head lamp case, where an internal cross-sectional area of the head lamp case may increase in a direction toward a front of the vehicle based on a position where the speaker is provided.
US11560101B2	Headliner-mounted telematics control unit package A roof structure of a motor vehicle includes an outer sheet and a headliner below the outer sheet. A telematics control unit (TCU) is disposed in an insulated space of the roof structure. The TCU is configured to provide Wi-Fi within a passenger space of the vehicle above an electrically non-conductive grille extending across an opening in the headliner. The grille permits airflow between the insulated space and a passenger space below the headliner to cool the TCU, without interfering with Wi-Fi signals from the TCU.
US11560100B2	Carrier element A carrier element is configured to securely store a foldable wheelchair that is mountable in an ambulette or other vehicle without interfering with passenger space in the vehicle.
US11560099B2	Collapsible cargo platform The disclosure relates generally to a cargo platform designed to be used in connection with a trailer hitch and, more particularly, to a cargo platform designed to be collapsible. A cargo platform has an open position and a closed position. The cargo platform includes a frame with a front portion, a rear portion, first and second stationary side portions coupled to the front portion, first and second rotatable side portions, a first hinge element to rotatably could the first rotatable side portion to the rear portion, a second hinge element to rotatably could the second rotatable side portion to the rear portion, and a foldable floor. The foldable floor includes a first floor, second floor rotatably connected to the first floor, and a third floor rotatably connected to the second floor. The first floor is coupled to the front portion. The third floor is coupled to the rear portion.
US11560096B2	Vehicle storage assembly A storage assembly for a vehicle includes a first harness assembly configured to selectively engage said vehicle. The first harness assembly includes a first inner support strap and a second inner support strap coupled to the first inner support strap in a crossing configuration. An inner connector strap is coupled to at least one of the first inner support strap and the second inner support strap. A second harness assembly is configured to selectively engage said vehicle. The second harness assembly includes a first outer support strap and a second outer support strap coupled to the first outer support strap in a crossing configuration. An outer connector strap is coupled to at least one of the first outer support strap and the second outer support strap. The outer connector strap of the first harness assembly selectively couples with the inner connector strap of the second harness assembly.
US11560094B2	Vehicular exterior lighting assembly with micro-LED lighting devices A vehicular exterior lighting assembly includes a plurality of lighting devices. The plurality of lighting devices includes a first lighting device operable to emit light for a first lighting function and a second lighting device operable to emit light for a second lighting function. A plurality of micro-LEDs of the lighting devices are disposed at electrically conductive traces of at least one flexible circuit element. Packing density of the micro-LEDs at the at least one flexible circuit element is at least 10 micro-LEDs per square centimeter. Each individual micro-LED of the plurality of micro-LEDs when operated to emit light passes less than 4 mA electrical current. With the vehicular exterior lighting assembly attached at an exterior portion of a vehicle, light emitted by the first lighting device and light emitted by the second lighting device, when operated to emit light, is viewable exterior the equipped vehicle.
US11560089B2	Bus with a variable height warning signal A bus, notably an articulated low platform bus with an electric drive or a hybrid drive. The bus includes a vehicle detection module configured for detecting vehicle such as a car, a van or a motorbike, a height obtaining module adapted for obtaining the height of the detected vehicle, and a lighting system with a lighting surface adapted for displaying a luminous picture at least partially or totally above the height of the detected vehicle. The height of the luminous picture is adapted depending on the size of the vehicle for visibility purposes.
US11560087B1	Housing for connecting a light bar to a vehicle A housing for connecting a light bar to a vehicle comprises at least a front surface comprising a lighting aperture, a first side surface, a second side surface opposite the first side surface, and a top surface defining a hollow interior. The housing further comprises at least a first bracket and a second bracket located within the hollow interior. The first bracket is configured to connect a first interior face of the housing to a first side of the light bar while the second bracket is configured to connect a second interior face of the housing to a second side of the light bar. At least a portion of at least one of the front surface, the first side surface, the second side surface, the first bracket, and/or the second bracket is configured to connect to a surface of the vehicle.
US11560085B2	Vehicle light assembly A vehicle includes a light assembly and an electric control module. The light assembly is assembled to an underbody of the vehicle. The light assembly has a light bar and an image projector. The light bar has a plurality of first light sources. The image projector has a housing that is fitted to a longitudinal end of the light bar. The housing has a circuit board and an emitting portion that houses a second light source. The circuit board is electrically connected to the second light source to regulate electric current to the light source. The electric control module is electrically connected to the light bar and the circuit board to provide electrical power to both the light bar and the image projector.
US11560080B2	Installation trailer for coiled flexible pipe and method of utilizing same A system includes a trailer frame, a lifting mechanism coupled to the trailer frame, wherein the lifting mechanism is configured to raise or lower a coil of pipe or a reel of pipe, a braking mechanism configured to apply pressure to the pipe while the pipe is being deployed by the system, and a hydraulic power unit configured to hydraulically power the system.
US11560076B2	Vehicle seat A seat back pad 70 has a groove 73 for tucking a skin material therein, formed at borders between a central portion 71 and side portions 72. A hole (slot hole 74) is formed in a bottom of the groove 73 along the groove 73. A tuck-in wire 76 for tucking the skin material in includes a plurality of tuck-in portions 76A provided along the groove 73, and a connecting portion (detour portion 76B) detouring around the hole and connecting the tuck-in portions 76A. With this configuration, when an upper body of an occupant P subsides into a seat back S2 in a rear-end collision of a vehicle, the central portion 71, defined by the groove 73 as a border, is easily and sufficiently moved rearward relative to the left and right side portions 72. Furthermore, the tuck-in wire 76 is not exposed through the hole, and thus adhesion between the seat back pad 70 and the tuck-in wire 76 can be improved.
US11560075B2	ISOFIX interface structure of vehicle seat The present invention provides an ISOFIX interface structure of a vehicle seat. The ISOFIX interface structure of the vehicle seat comprises a shroud mounting base and two ISOFIX shrouds. Two mounting holes are formed in the shroud mounting base, and the mounting holes are penetrated from front to rear. The two ISOFIX shrouds can correspondingly be inserted into the corresponding mounting holes and can be detachably mounted on the shroud mounting base. According to the ISOFIX interface structure of the vehicle seat, the structure is novel, neat, attractive, and easy to realize. The problem is that conventional ISOFIX interfaces collapse surrounding seat foam when being installed. Here, consistency of the two ISOFIX interfaces on the same vehicle seat is guaranteed, the subsequent installation of a child safety seat is convenient, and the assembly and disassembly efficiency of the child safety seat can be effectively improved.
US11560074B2	Vehicle seat, method for mounting auxiliary seat, and structure for mounting auxiliary seat A vehicle seat includes a seat face part, a back face part, and a fixing member for fixing an auxiliary seat, which is disposed between the seat face part and the back face part. The seat face part includes a seat face recess capable of housing a lower face side of a seat part of an auxiliary seat, and a seat face cushion that is detachably attached to the seat face recess. The back face part includes a back face recess capable of housing a rear face side of a back part of the auxiliary seat, and a back face cushion that is detachably attached to the back face recess.
US11560068B2	Circuit arrangement for a vehicle electrical system of an electrically driven motor vehicle and method for operating a circuit arrangement of this type The invention relates to a circuit arrangement (24) for a vehicle electrical system of an electrically driven motor vehicle (42), comprising: a high-voltage battery (26) for supplying power to an electrical drive machine (28) of the motor vehicle (42); a range extender (22), which is designed to charge the high-voltage battery (26) and which has a plurality of identical fuel-cell base modules (10) having interfaces for supplying reactants in the form of hydrogen and air; a switching device (32) for connecting the range extender (22), the circuit arrangement (42) having no DC-to-DC converter; a control device (36) which is designed to carry out the following steps after the control device has received an activation signal regarding the range extender (22): determining an operating point of the range extender (22) in dependence on at least one variable of the high-voltage battery (26); defining a setpoint value regarding the supply of the reactants to the fuel-cell base modules (10) and/or a setpoint value regarding an operating temperature of the fuel cells on the basis of the determined operating point; controlling a system (40), which is designed to provide the reactants to and/or to control the temperature of the fuel cells, in accordance with each defined setpoint value; controlling the switching device (34) so as to connect the range extender (22), only after the setpoint value regarding the supply of the reactants and/or the setpoint value regarding the operating temperature has been reached. The invention further relates to an electrically driven motor vehicle (42) having the circuit arrangement (24), and to a method for operating the circuit arrangement (24).
US11560067B2	Apparatus and method for processing battery cell voltage data An apparatus and a method for processing battery cell voltage data, which calculate a moving average by assigning a weight to one or more voltage data acquired from the battery cell and reflect the acquired voltage data to the calculated moving average and use the voltage data to rapidly follow a sudden change of the voltage data applied from the battery cell.
US11560061B2	Motor drive device and electric vehicle system A motor drive device includes a power conversion circuit that drives an AC motor and a controller that controls the power conversion circuit. The controller includes a command current calculation unit generating a command current according to command torque for the AC motor and a current control unit that performs feedback control for adjusting a current applied to the AC motor to the command current. The controller also includes a control gain setting unit that calculates a control gain used for the feedback control based on the command torque and sets the calculated control gain in the current control unit. The control gain setting unit performs control such that a time from a decrease of an absolute value of the command torque to switching of the control gain is longer than a time from an increase of the absolute value of the command torque to switching of the control gain.
US11560060B2	Power supply device A power supply device is provided with a disconnection means (AND element) for forcibly disconnecting a battery module from a series connection regardless of a gate signal. The power supply device forcibly disconnects partial battery modules from the series connection by the disconnection means (AND element) during powering by a power supply output, thereby performing control so that the accumulated discharge current amounts thereof per unit time become smaller than those of the other battery modules.
US11560055B2	Self-balancing two-wheeled vehicle In an aspect, a self-balancing two-wheeled vehicle is provided, having a body, and first and second wheels rotatably coupled to the body. The second wheel has at least one lateral roller rotatable about an axis that is one of oblique and orthogonal to a rotation axis of the second wheel. At least one motor is coupled to the second wheel to control rotation of the second wheel and the at least one lateral roller. At least one sensor is coupled to the body to generate orientation data therefor. A control module is coupled to the at least one motor to control operation thereof at least partially based on the orientation data generated by the at least one sensor.
US11560047B2	Support apparatus for an off-axle load A vehicle including a frame having an axle and a support apparatus coupled thereto. The support apparatus is configured to support a load coupled to the axle and permit the load to translate along an x-axis, a y-axis, and a z-axis.
US11560043B2	Passenger cabin air distribution system and method of using A passenger cabin air distribution system includes a ventilation system and an ejector-diffuser. The ventilation system is operable to provide a conditioned air. The ejector-diffuser is positioned to receive a flow of the conditioned air from the ventilation system. The ejector-diffuser includes an induction unit and a diffuser section. The induction unit includes a secondary inlet in communication with a cabin air from a passenger cabin and is configured to mix the flow of the conditioned air with an induced flow of the cabin air into a mixed air. The diffuser section includes a discharge to eject the mixed air to the passenger cabin. The diffuser section is shaped to provide for efficient mixing with low backpressure in order to maintain the low motive pressure in the nozzle.
US11560041B1	Vehicle thermal system A vehicle thermal system includes a heat-generating component, a heat-absorbing component, a liquid coolant reservoir for receiving and distributing a liquid coolant, a first liquid loop that is connected to the liquid coolant reservoir, includes a first pump upstream from a first functional component to circulate the liquid coolant, is heated by the heat-generating component, and includes a first valve downstream from the first functional component to control recirculation or return of the liquid coolant to the liquid coolant reservoir, and a second liquid loop that is connected to the liquid coolant reservoir, includes a second pump upstream from a second functional component to circulate the liquid coolant, is cooled by the heat-absorbing component, and includes a second valve downstream from the second functional component to control recirculation or return of the liquid coolant to the liquid coolant reservoir.
US11560034B1	Situation-based vehicle configuration Particular embodiments may enable configuring settings of a vehicle in a designated mode. A signal to place the vehicle in a designated mode may be received. A roll angle and a pitch angle of the vehicle as parked may be assessed based on data received from a position sensor built into the vehicle. Signals to adjust an electronically controlled suspension of the vehicle to reduce the roll angle or the pitch angle so that the vehicle is level as parked may be sent based on the assessed roll angle and pitch angle exceeding a threshold value. One or more settings of the vehicle to change default operating characteristics by the vehicle while in the designated mode may be modified.
US11560033B2	Vehicle with road surface condition detector A vehicle with a road surface condition detector includes: a vehicle body configured to have one or more passengers; front and rear wheels configured to move the vehicle body; and a road surface condition detector configured to detect road surface conditions in front of the front and rear wheels, wherein the road surface condition detector includes front-wheel road surface condition detectors configured to detect road surface conditions in front of the front wheels and rear-wheel road surface condition detectors configured to detect road surface conditions in front of the rear wheels, and the rear-wheel road surface condition detectors detect areas located outer in a vehicle width direction than ends of detection areas detected by the front-wheel road surface condition detectors.
US11560032B2	System and method for determining whether to adjust the ride height of a vehicle The present invention relates to a system for determining whether to inhibit lowering of the ride height of a vehicle when the vehicle speed exceeds a speed threshold value. The system includes a processor having an input configured to receive ride attribute data from at least one on-board vehicle ride attribute sensor, the ride attribute data being indicative of the roughness of the surface over which the vehicle is travelling, and a data memory configured to store at least one predetermined ride attribute threshold value for the or each ride attribute sensor. The processor is configured to calculate a ride attribute parameter in dependence on the received ride attribute data for the or each ride attribute sensor. The processor is also configured to compare the or each calculated ride attribute parameter with the corresponding at least one predetermined ride attribute threshold value to determine whether the vehicle is travelling on a smooth surface or a rough surface, and to inhibit lowering of the ride height when it is determined that the vehicle is travelling on a rough surface.
US11560031B2	Methods and apparatus to determine vehicle weight Methods and apparatus to determine vehicle weight are disclosed. An example apparatus includes a vehicle controller configured to control a motor operatively coupled to a suspension system to raise or lower a vehicle. The vehicle controller is to also determine a first parameter of the motor while controlling the motor to raise or lower the vehicle when the vehicle is unloaded. The vehicle controller is to also determine a second parameter of the motor while controlling the motor to raise or lower the vehicle when the vehicle is at least partially loaded. The vehicle controller is to also calculate a weight of the vehicle based on the first and second parameters of the motor.
US11560028B2	Methods and apparatus for payload estimation and hitch condition detection using integrated sensors Methods, apparatus, systems and articles of manufacture are disclosed for payload estimation and fault detection using hitch integrated sensors. An example apparatus includes a pin orientation determiner to determine a first orientation of a first pin and a second orientation of a second pin, the first pin and the second pin disposed within a hitch and calculate a relative orientation of the first pin and the second pin based on the first orientation and the second orientation. The example apparatus further includes a hitch condition detector to determine if a physical change has occurred in the hitch by comparing the relative orientation to an installation orientation of the first pin and the second pin.
US11560027B2	Underbed hitch mounting system An underbed hitch mounting system is described. The mounting system may be utilized for towing vehicles wherein the mounting system may selectively accommodate either a fifth wheel hitch or a gooseneck hitch. The mounting system may include at least one rail capable of being connected to a vehicle frame, wherein the rail includes at least one socket. The socket may be engaged with a receiving member, wherein the receiving member may be engaged with a leg of a fifth wheel hitch. A mid rail may be connected to the rails and may include a hitch ball socket that is capable of engagement with a hitch.
US11560025B2	Process for tire dismount Described herein is a method for dismounting a tire from a wheel assembly. The method may comprise inserting at least a first finger and a second finger between a top bead of a tire and a top bead seat of a wheel, pulling a portion of at least the top bead past a plane defined by the outer edge of the top bead seat, and moving the first finger in a first rotational direction away from the second finger. Also described herein is a finger for dismounting a tire from a wheel. The finger may comprise at least one roller having two opposing ends, each end connected to a corresponding end of a roller nest of the finger. Also described herein is an apparatus for removing a tire from a wheel. The apparatus may comprise a wheel alignment assembly, a tire dismount assembly, a bead lifter, and a rotation assembly.
US11560020B2	Tire comprising optimized architecture and tread pattern A tire (1) for a vehicle has a tread surface having a transverse radius RT and comprises a crown layer (3) that comprises at least one undulation (312) in line with a rib (26). The undulation (312) is such that it is radially on the outside of the points of the undulated layer in line with the center of the bottom face of the circumferential furrow (25) closest to the undulation (312) and has an amplitude at least equal to 1 mm. The radial distance (da) between at least one contact edge corner of a rib (26) in line with which an undulation is located and the transverse radius RT of the rib is at least equal to 0.2 mm and at most equal to 2 mm.
US11560017B2	Adjustable axle assembly for a vehicle An axle assembly for a vehicle. A movable housing is movably positioned within a closed channel defined by a central housing. The movable housing moves the axle assembly between a retracted configuration and an extended configuration. A mounting assembly may be coupled to and spaced from the movable housing and slidably positioned adjacent the central housing. A steering actuator is coupled to a steering arm and the mounting assembly such that the steering actuator moves as a unit. A track assist bracket may be fixedly coupled to the central housing and define a gap sized to slidably receive a mounting plate of the mounting assembly. A bushing may be disposed on each wall of a telescoping portion of the movable housing. A bellows may be provided to enclose exposed portions of the bushings in the extended configuration. Methods of adjusting the track of the axle assembly are also disclosed.
US11560015B2	Wheel hub A sensor is mounted to or embedded in a wheel hub. The sensor node includes a power source and a sensing device that detects and monitors at least one parameter associated with the wheel hub. The sensor node also includes a communication module that communicates via wireless communication signals and a processing device in communication with the sensing device and the communication module. The processing device collects data from the sensing devices, processes the data, and based on that processing, communicates information relating to the wheel hub to a remote server or network. A mesh network of multiple sensor nodes can be applied to multiple different wheel hubs on a vehicle and communicate with a central processing device. The processing device can thus monitor performance and/or operation of each wheel hub.
US11560014B2	Nanostructured surfaces The present invention is directed to methods for inhibiting growth of bacteria and to nanometer scale surfaces having antibacterial properties.
US11560011B2	Method for pretreating materials for flexography by means of mobile low-temperature plasma application Where printing plate is to be secured to a plate cylinder by means of double-sided adhesive tape, the surface of the printing plate to be secured to the plate cylinder is, prior to bonding, partially pre-treated by means of a low-temperature plasma pencil after cleaning with isopropanol.
US11560010B2	On-machine development-type lithographic printing plate precursor and method for producing lithographic printing plate An on-machine development lithographic printing plate precursor includes an image-recording layer on an aluminum support having an anode oxide film, wherein an end portion of the lithographic printing plate precursor has a shear droop shape, the image-recording layer contains a compound having a support adsorptive property, having a molecular weight of 1,000 or less, and not having an unsaturated double bond group in a molecule, and a content of the compound is substantially the same in a plane of the image-recording layer.
US11560009B2	Stamps including a self-assembled block copolymer material, and related methods Methods for fabricating stamps and systems for patterning a substrate, and devices resulting from those methods are provided.
US11560004B2	Liquid ejection apparatus and delivery system for liquid ejection head A liquid ejection apparatus includes a liquid ejection head that is detachably attached and ejects a liquid, and a control section that is configured to transmit a delivery request for a new liquid ejection head to a server apparatus via a network.
US11559998B2	Retractable printable medium support A printable medium support for a printer comprises a support element to support a printable medium, wherein the support element is movable between a protruding configuration to support the printable medium, and a retracted configuration in which the support element is at least partially retracted in a first direction. The printable medium support comprises an actuating element to move the support element between the protruding configuration and the retracted configuration.
US11559996B2	Ink jet printer production techniques Techniques for operating a printer are provided. In an example, the printer can include a print head a cure light and a controller. The controller can be configured to move the print head relative to a print media to print a given image, to move the cure light relative to the print media at a cure speed in response to the cure light passing over a printed portion of the given image to cure the ink of the given image, and to move the cure light at an index speed in response to the cure light passing over a non-printed portion of the given image, wherein the index speed is greater than the cure speed.
US11559995B2	Printer and printing method A printer includes a printing head, a nail information detection unit, an outline comparison determination unit, and a display unit. The printing head prints on a print target. The nail information detection unit detects a base outline that is a base outline in an area including the print target and a non-print target adjacent to the print target. The outline comparison determination unit compares a print outline that is an outline of an area to be printed on the print target with the base outline, and determines whether or not there is a difference equal to or larger than a set value. The display unit reports, as a reporting unit, to a user that the difference determined by the outline comparison determination unit is equal to or larger than the set value.
US11559985B2	Integrated circuit with address drivers for fluidic die An integrated circuit for a fluidic die including an address bus to communicate a set of addresses, a first group of die configuration functions including a first address driver to drive a first portion of an address of the set of addresses on the address bus, a second group of die configuration functions including a second address driver to drive a second portion of the address of the set of addresses on the address bus, and an array of fluid actuating devices addressable by the set of addresses communicated via the address bus.
US11559983B2	Method for creating a print control profile for printing on a contoured axially symmetric object A process is disclosed for creating a print profile to control the operation of a direct-to-shape printing system for applying images on the exterior of an axially symmetrical media object that has a contoured, varying exterior surface, such as occurs on curved wine bottles and sports equipment like bats. The process takes a media recipe holding media geometry information and an image intended to be printed and processes that information to control a motion control subsystem and a print engine subsystem. The geometry information is manipulated to generate a CAM table suitable for the motion control subsystem, and the image file is processed to create a raster image file suitable for ink head expression. Various setup values are included in the process to prepare the direct-to-shape printing system for use of the media recipe.
US11559982B2	Digital printing process A printing process is disclosed which comprises directing droplets of an ink onto an intermediate transfer member to form an ink image, the ink including an organic polymeric resin and a coloring agent in an aqueous carrier, and the transfer member having a hydrophobic outer surface so that each ink droplet in the ink image spreads on impinging upon the intermediate transfer member to form an ink film. The ink is dried while the ink image is being transported by the intermediate transfer member by evaporating the aqueous carrier from the ink image to leave a residue film of resin and coloring agent. The residue film is then transferred to a substrate. The chemical compositions of the ink and of the surface of the intermediate transfer member are selected such that attractive intermolecular forces between molecules in the outer skin of each droplet and on the surface of the intermediate transfer member counteract the tendency of the ink film produced by each droplet to bead under the action of the surface tension of the aqueous carrier, without causing each droplet to spread by wetting the surface of the intermediate transfer member.
US11559978B2	Printing machine and system for rotary screen printing including a screen-printing cylinder having flexible surface elements A printing system for rotary screen printing includes a screen-printing cylinder having flexible surface elements. The flexible surface elements give way upon contact with sheet grippers projecting from an impression cylinder, so that it is not necessary to move the screen-printing cylinder out to avoid contact with the sheet grippers. A screen-printing cylinder, a method for producing a screen-printing cylinder, a printing machine and a method for using a screen-printing cylinder, are also provided.
US11559977B2	Plate sleeve-holder cylinder made of carbon-fibre composite material for flexographic printing and including compressed air channels A plate sleeve-holder cylinder provided with a carbon-fibre central tube (T) comprising compressed air channels (6, 7, 8) arranged between one of the end flanges (Fb, Fm) of said plate sleeve-holder cylinder and a plurality of holes (H) formed in the outer surface of said central tube (T) made of carbon-fibre composite material. Said air channels (6, 7, 8) are partly embedded within said end flanges (Fb, Fm), partly within a thickness of a side wall (P) of said central tube (T) made of carbon-fibre composite material. Additionally, a process of manufacturing said central tube (t) is disclosed by inserting air pipes (6) into grooves (1) which are formed by mechanical milling of a surface of the supporting structure (P) of said central tube (T) obtained through a first lamination and polymerization, said grooves being coated with a surface finishing structure (S) obtained through a second lamination and polymerization.
US11559970B2	Thin-film devices and fabrication Thin-film devices, for example electrochromic devices for windows, and methods of manufacturing are described. Particular focus is given to methods of patterning optical devices. Various edge deletion and isolation scribes are performed, for example, to ensure the optical device has appropriate isolation from any edge defects. Methods described herein apply to any thin-film device having one or more material layers sandwiched between two thin film electrical conductor layers. The described methods create novel optical device configurations.
US11559969B2	Laminated glass and method of manufacturing the same A laminated glass comprising an outer glass sheet, an inner glass sheet, and an intermediate layer between the outer and inner glass sheets. The intermediate layer has a first busbar, a second busbar, and heating wires connecting the first and second busbars, and a sheet-like substrate supporting the heating wires. The intermediate layer further comprises an adhesive layer. A distance from a centre of the wires to a surface the outer glass sheet and a distance from the centre of the wires to a surface the inner glass sheet being different; and a distance from the centre of the wires to the inside surface of the outer glass sheet and a distance from the centre of the wires to the outside surface of the inner glass sheet being different, and the adhesive layer thickness or the substrate thickness, whichever is smaller, is not more than 400 micrometres.
US11559965B2	Shaped part and method for producing a shaped part A shaped part can comprise an opaque decorative layer, at least two symbols on the front side, a translucent base, the decorative layer having one or more first light channels, one or more first functional having a first light element, a first functional layer on the rear side of the base, the first functional elements on the front side of the first functional layer, the decorative layer having one or more second light channels, one or more second functional elements having a second light element, a second functional layer on the rear side of the decorative layer, the second functional elements in or on the second functional layer, and being provided at least partially in the second light channels, the second functional elements covering the second light channels of the decorative layer such that the second light channels become or are shielded from light of the first light elements.
US11559960B2	Tire with an element attached to the surface thereof and method for attaching an element to the surface of a tire A tire comprises an interior surface and an exterior surface, an accommodating region arranged on one of said interior and exterior surfaces, an adhesive layer arranged on the accommodating region and a member attached to the accommodating region by the adhesive layer, in which the adhesive layer is based on a silanized polyether.
US11559956B2	Method and apparatus for rapid continuous consolidation of thermoplastic components A method and structure for processing a plurality of prepreg sheets includes a conveyor assembly having a first conveyor, a second conveyor, and a processing zone positioned between the first and second conveyors. In an implementation, a plurality of prepreg sheets are advanced from a plurality of material supply creels into the processing zone by a first conveyor and a second conveyor turning in opposite directions. Within the processing zone, a compressive pressure is applied to the prepreg sheets by first pressure plates attached to first conveyor and second pressure plates attached to the second conveyor. A thermoplastic within the prepreg sheets is melted within the processing zone by a heater to consolidate the prepreg sheets into a consolidated laminate.
US11559952B2	Three-dimensional shaping system and three-dimensional shaped object manufacturing method A three-dimensional shaping system includes a first table provided with a first positioning mechanism, a first shaping machine configured to shape a first shaped object on the first table, a first cutting machine provided with a first mounting portion having a second positioning mechanism and configured to cut the first shaped object, a conveying machine configured to convey the first table between the first shaping machine and the first cutting machine, and a control unit configured to control the first shaping machine, the first cutting machine, and the conveying machine. The control unit controls the first shaping machine to shape the first shaped object, controls the conveying machine to convey the first table from the first shaping machine to the first cutting machine so that the first and second positioning mechanisms engage with each other, and controls the first cutting machine to cut the first shaped object.
US11559951B2	Composite component The invention relates to a composite component that has improved bonding properties and includes a substrate (i) made of a thermoplastic polymer blend composition, and a coating (ii); in a layer located 5 to 10 μm below the boundary surface between the substrate (i) and the coating (ii), the substrate (i) has a dispersed, non-lamellar phase structure. The invention also relates to a method for manufacturing the composite component.
US11559950B2	Adjustable sealing bar for pre-applied bottom gusset package and method of using the same A set of sealing jaws incorporating an adjustable seal area to seal the vertical portion of a bottom gusseted style of package. An adjustable seal surface allows a packaging machine to run different film web widths without the need to change jaws. The sealing jaws to be converted to run bottom gusset packages to pillow packages without the requirement to change jaws.
US11559949B2	Method for connecting two unitary elements of a conduit for transporting fluids by means of a sleeve A method of connecting together two unit elements (4, 4′) of a fluid transport pipe, each unit pipe element being covered in an outer insulating coating (6, 6′) made of a thermoplastic material, with the exception of an end portion that does not have an outer insulating coating. The method includes: a step of welding together two abutting unit pipe elements; a step of positioning an annular sleeve (14) around a cut-back and in part around the outer insulating coatings of the two unit pipe elements, the sleeve being made of a thermoplastic material; a step of fastening the sleeve in sealed manner by weld bonding on the outer insulating coatings; and a step of applying an external pressure on the sleeve to enable it to be deformed elastically and match the shape of the respective end portions of the two unit pipe elements.
US11559945B2	Membrane assembly for a 3D printing system A tank assembly for a 3D printing system may include a membrane assembly that is releasably secured to a bottom rim of a tank sidewall of the tank assembly. The securing mechanism may include one or more of a friction-fit coupling and a magnetic coupling. The membrane assembly may include a frame, a radiation-transparent flexible membrane and a membrane securing member. A peripheral portion of the flexible membrane may be secured within a groove of the frame by the membrane securing member. The tank sidewall may include one or more components for supplying fresh resin to the tank assembly and one or more components for draining used resin from the tank assembly.
US11559942B2	Three-dimensional object molding method and molding device A three-dimensional object molding method and molding device, where the method includes the following steps: forming a powder particle layer, wherein the powder particle layer at least contains thermosetting powder particles capable of undergoing thermal polymerization; spraying a photocurable material onto the powder particle layer according to layer printing data, such that the photocurable material covers at least part of the powder particle layer and permeates into this layer; curing the photocurable material to form a slice layer; repeating the steps to obtain a plurality of slice layers, and stacking the plurality of slice layers layer-by-layer to form a three-dimensional object green body; and heating the green body to thermally polymerize the thermosetting powder particles so as to obtain the three-dimensional object. The method provided in the present application enables the obtained three-dimensional object to have very good mechanical properties and a high molding accuracy.
US11559941B2	Selective laser solidification apparatus and method A method of selecting a scanning sequence of a laser beam in a selective laser solidification process, in which one or more objects are formed layer-by-layer by, repeatedly, depositing a layer of powder on a powder bed and scanning a plurality of laser beams over the deposited powder to selectively solidify the powder layers, wherein a gas flow is passed over the powder bed in a gas flow direction. The method including selecting a scanning sequence for the plurality of laser beams to include the simultaneous exposure of an upstream point together with a downstream point located downstream of a flow of debris carried from the upstream point by the gas flow, the downstream and upstream points selected for simultaneous exposure based upon the downstream point being within a maximum separation distance from the upstream point.
US11559938B2	Method of layerwise building up an object and a 3D printing device for performing such a method A method of layerwise building up an object from at least a first and a second light hardenable resin on a 3D printing device, and a 3D printing device that is configured to perform such a method. The 3D printing device has a build platform on which the object can be built up, a light-transmissive carrier comprising a plurality of recesses and a light projector for projecting a light-pattern through the carrier. The method has the steps of (a) partially building up the object and thereby providing an object-in-process; (b) coating a first surface area of the carrier with a first blank layer of the first light hardenable resin; (c) moving the carrier and thereby positioning the first blank layer between the build platform and the light projector; (d) bringing the object-in-process into contact with the first blank layer; (e) irradiating the first blank layer with a light pattern and thereby supplementing the object-in-process by a hardened layer; and (f) separating the supplemented object-in-process from the carrier.
US11559935B2	Method and printing system for printing a three-dimensional structure, in particular an optical component A method and printing system for printing a three-dimensional structure, in particular an optical component, by depositing droplets of printing ink side by side and one above the other in several consecutive depositing steps by means of a print head. In each depositing step a plurality of droplets is ejected simultaneously by a plurality of ejection nozzles of the print head. The print head is moved relative to the deposited droplets in a moving step performed between at least two consecutive depositing steps in such a manner that the droplets deposited in the same position in the at least two consecutive depositing steps are ejected at least partly from two different ejection nozzles.
US11559934B2	Heating device for the temperature conditioning of preforms, and method for operating a heating device of this kind A method for operating a heating device for thermal conditioning preforms made of a thermoplastic material in which each respective one of the preforms is prepared for a subsequent forming process during which the preforms are formed into containers with a forming fluid fed under pressure into the preforms. The heating device is operated in at least a first operating state and a second operating state. The second operating state is a startup phase of the heating device during which a temperature of the heating device approaches an equilibrium temperature of a thermodynamically stable equilibrium state of the heating device. The first operating state is a continuous operation state following the startup phase. The second operating state is operated with a heating output value that varies over time. Furthermore, the invention relates to a heating device and a machine having a heating device, which are configured to implement the method.
US11559931B2	Resin tank and method for manufacturing resin tank A resin tank and a method for manufacturing a resin tank in which positional deviation and deformation of an inserted member is prevented. In a resin tank formed through resin injection molding, a gradually changing thickness portion in which a thickness of a resin layer gradually changes from one side to the other side with respect to a surface of an insert plate for attachment of an auxiliary component is formed in the resin layer at a region into which the insert plate is inserted.
US11559926B2	Method of producing separator plates by compaction and a production facility A method for producing a separator plate, where thermoplastic polymer material and a powder of electro-conductive filler, ECF is kneaded at a kneading temperature above a glass transition temperature for the thermoplastic polymer material but below a melting temperature for the thermoplastic polymer material in order to provide a malleable but not molten compound and for causing fibrillization in the thermoplastic polymer material prior to hot-compacting the sheet in a press-form to form a separator plate. A production facility for practicing the method is also disclosed.
US11559924B2	Concrete forming systems and methods Systems and methods for constructing concrete foundations are provided which allow for rapid and high-precision placement and alignment of anchor bolts across large distances. A frame system is constructed outside of an excavation and then suspended, using supports, over an excavation. The frame system can include a frame having one or more templates for anchor bolts, a form suspended from the frame, and a mat and cage assembly tied to the frame. The frame system can be aligned in proper position and the anchor bolts placed in the frame system before the concrete is placed. In this way, the anchor bolts can be cast in place as the footing is placed.
US11559923B2	Method for preparing polyamide-imide film One embodiment relates to a method for preparing a polyamide-imide film which is colorless and transparent and has good mechanical properties, easily and efficiently in terms of yield. Particularly, the embodiment relates to a preparation method capable of obtaining a polyamide-imide film of which the optical characteristics, mechanical properties and flexibility are harmoniously improved without complicated processes, by controlling the amount of imide repeating units and amide repeating units constituting the polyamide-imide film.
US11559921B2	Preforms for blow molding and additive manufacturing thereof A preform and methods for making the preform, as well as containers made by blow molding an additive manufactured preform.
US11559920B2	Seal gasket element for a mixing apparatus, method for obtaining and applying the same, and special equipment for fitting the same A method for obtaining and applying a sealing gasket element on a slide-valve sliding in a cavity of an apparatus for the recirculation and mixing of chemically reactive polymeric components, comprises the steps of: obtaining from an elastic-plastic material a precursor element of the seal element, with a grid structure having a reticular shape; positioning the precursor element around the slide-valve; exerting on the precursor element, through temporary clamping elements, a radial compression and contraction action to insert it and couple it to one or more housing seats provided on the slide-valve so as to obtain the seal element well coupled to the latter; progressively removing the clamping elements to sequentially release successive parts of the gasket element and gradually free the slide-valve to gradually introduce the parts of the slide-valve—freed in succession—in the housing cavity allowing the sealing gasket element to gradually expand radially due to the elastic return by adhering tightly to the inner surface of the same housing cavity. The special equipment for fitting the sealing gasket element on the slide-valve and the so obtained recirculation and mixing apparatus is also described.
US11559918B2	Additively manufactured composite components An example technique includes extruding, by a tow deposition device, on a tow-by-tow basis, respective impregnated tows of a plurality of respective impregnated tows to form a layer of material on a major surface of a substrate. Each respective impregnated tow includes at least one ceramic fiber and a curable resin coating the at least one ceramic fiber. The example technique includes curing the curable resin to form a cured composite component. An example system includes a tow deposition device, an energy source, and a computing device. The computing device is configured to control the tow deposition device to extrude, on a tow-by-tow basis, respective impregnated tows of a plurality of respective impregnated tows to form a layer of material, and is configured to control the energy source to cure the curable resin to form a cured composite component.
US11559916B2	Electric working machine An electric working machine may include: a support rod constituted of metal; a tool disposed at a front end of the support rod; a motor configured to drive the tool; a control unit disposed at a rear end of the support rod and configured to control the motor; and a heat transfer structure configured to transfer heat from the control unit to the support rod.
US11559906B1	Apparatus and method for object mounting system Embodiments of an active object mounting system secure an object of interest to a surface of a secured-to object using one or more vacuum mounting modules, wherein each vacuum mounting module comprises at least one vacuum pump controllably coupled to a microcontroller, a vacuum cup fluidly coupled to the at least one vacuum pump, and a transceiver that receives an instruction corresponding to one of a vacuum cup actuation signal or a vacuum cup release signal.
US11559905B2	Subsea manipulator A subsea manipulator for a remotely operated underwater vehicle (ROV) that includes at least one linear, oil-filled electric actuator to control a motion of the manipulator in a subsea environment is disclosed. The remotely operated underwater manipulator includes an electric actuator for each axis of motion of the manipulator, and an end effector that includes a rotational joint and a tool motor for controlling a tool affixed to the end effector. A method for changing the tool of the manipulator in a subsea environment is disclosed.
US11559900B2	Systems, devices, components, and methods for a compact robotic gripper with palm-mounted sensing, grasping, and computing devices and components Disclosed are various embodiments of a three-dimensional perception and object manipulation robot gripper configured for connection to and operation in conjunction with a robot arm. In some embodiments, the gripper comprises a palm, a plurality of motors or actuators operably connected to the palm, a mechanical manipulation system operably connected to the palm, a plurality of fingers operably connected to the motors or actuators and configured to manipulate one or more objects located within a workspace or target volume that can be accessed by the fingers. A depth camera system is also operably connected to the palm. One or more computing devices are operably connected to the depth camera and are configured and programmed to process images provided by the depth camera system to determine the location and orientation of the one or more objects within a workspace, and in accordance therewith, provide as outputs therefrom control signals or instructions configured to be employed by the motors or actuators to control movement and operation of the plurality of fingers so as to permit the fingers to manipulate the one or more objects located within the workspace or target volume. The gripper can also be configured to vary controllably at least one of a force, a torque, a stiffness, and a compliance applied by one or more of the plurality of fingers to the one or more objects.
US11559898B2	Teleoperation system, method, apparatus, and computer-readable medium Embodiments of the present disclosure provide a system, method, apparatus and computer-readable medium for teleoperation. An exemplary system includes a robot machine having a machine body, at least one sensor, at least one robot processor, and at least one user processor operable to maintain a user simulation model of the robot machine and the environment surrounding the robot machine, the at least one user processor being remote from the robot machine. The system further includes at least one user interface comprising a haptic user interface operable to receive user commands and to transmit the user commands to the user simulation model, a display operable to display a virtual representation of the user simulation model.
US11559897B2	Reconfigurable, fixtureless manufacturing system and method assisted by learning software Systems and methods for AI assisted reconfigurable, fixtureless manufacturing is disclosed. The invention eliminates geometry-setting tools (hard points, pins and nets—traditionally known as 3-2-1 fixturing schemes) and to replace the physical geometry setting with virtual datums driven by learning AI algorithms. A first type of part and a second type of part may be located by a machine vision system and moved by material handling devices and robots to locations within an assembly area. The parts may be aligned with one another and the alignment may be checked by the machine vision system which is configured to locate datums, in the form of features, of the parts and compare such datums to stored virtual datums. The parts may be joined while being held by the material handling devices or robots to form a subassembly in a fixtureless fashion. The material handling devices are able to grasp a number of different types of parts so that a number of different types of subassemblies are capable of being assembled. The system enables one skilled in the art to develop a product design with self-locating parts that will eliminate and minimize the need for geometry setting dedicated line tools and fixtures. This leads to the development of a manufacturing process that utilizes the industry 4.0 technologies to once again eliminate or significantly reduces the need for geometry setting line tools.
US11559885B2	Method and system for grasping an object The method for increasing the accuracy of grasping an object can include: labelling an image based on an attempted object grasp by a robot and generating a trained graspability network using the labelled images. The method can additionally or alternatively include determining a grasp point using the trained graspability network; executing an object grasp at the grasp point S400; and/or any other suitable elements.
US11559882B2	Torque sensor Aspects of the disclosure include a torque sensor arrangement configured to attach between a first part and a second part to sense torque therebetween, the torque sensor arrangement comprising an interface member having on its exterior an engagement configuration configured to rotationally engage the first part, a torsion member comprising a deflectable body attached at one end thereof to the interface member and comprising, at the other end of the deflectable body, an engagement configuration configured to fixedly engage the second part, and a deflection sensor attached to the deflectable body, wherein the interface member defines a rigid sleeve extending around the deflectable body and the torque sensor arrangement further comprises a bushing located between and in contact with both the sleeve and the deflectable body.
US11559879B2	Power tool A power tool can absorb the shock from suspension resulting from falling while preventing the power tool from falling on the ground. A power tool includes a tool holder attachable to the power tool. The tool holder includes an annular portion that receives a suspension member through the annular portion, a base supporting the annular portion, and at least one bend located between the annular portion and the base.
US11559878B2	Multi-use tool A tool includes a handle and a blade. The handle extends from a handle first end to a handle second end. The blade has a first surface and an opposed second surface and defines a cutting edge between the first surface and the second surface. The blade extends from a blade first end to a blade second end. The blade and the handle are rotatably coupled at the blade first end and the handle first end about an axis extending from the first surface of the blade to the second surface of the blade. The blade is rotatable from a first position to a second position. The blade is lockable in the first position. When in the first position, the blade extends out from the handle second end.
US11559872B2	Device and method for the surface treatment of a material A device and a method for the surface treatment of a material by a pressurized jet of liquid nitrogen, supercritical cryogenic nitrogen or hypercritical cryogenic nitrogen that may be loaded with particles, use a device that includes a mixing chamber (10) closed by a downstream wall with an outlet orifice, and a diffusion focusing barrel (20) having an inlet and an outlet, the inlet being designed to be fastened to the mixing chamber (10) while being in fluid contact with the outlet orifice of the mixing chamber (10), the pressurized jet of nitrogen having to pass through the focusing barrel from the inlet to the outlet. The diffusion focusing barrel (20) includes a hollow tube having three successive portions placed one after the other, namely a convergent portion (21) located on the side of the inlet opening of the diffusion focusing barrel and whose inner face, considered in the direction of flow of the nitrogen jet, is convergent, a neck (22) whose inner face is cylindrical, and a divergent portion (23) ending in the outlet of the diffusion focusing barrel and whose inner face, considered in the direction of flow of the nitrogen jet, is divergent.
US11559867B2	Motor control device and industrial machine for suppressing vibration A motor control device includes an acceleration detecting section configured to detect an acceleration of a control object, and an acceleration control section configured to control an acceleration of a motor driving the control object based on the detected acceleration, in which the acceleration control section includes a vibration component extraction filter configured to extract a vibration component generated between the motor and the control object, and the vibration component extraction filter changes a filter characteristic frequency according to at least one of a position and a mass of the control object.
US11559864B2	Tool changer device for a robotic arm A tool changer device for a robotic arm comprising a robot adapter (1) particularly adapted to be connected to a robotic arm (5) and to a tool (6). The robot adapter (1) comprises a pneumatic cylinder (117) inside which a piston (116) is slidably arranged for activating a coupling and uncoupling mechanism (120) of the robotic arm (5) to the tool (6). On one of the walls of the robot adapter (1) at least four through conduits (24, 25, 26, 27) are arranged, one end of which opens into the pneumatic cylinder (117) and another end of which opens outside of the pneumatic cylinder (117). The device further comprises a first differential pressure sensor (18) connected to at least two of the through conduits (24, 25), and a second differential pressure sensor (19) connected to another two of the through conduits (26, 27).
US11559863B2	C-axis unit for a machine tool with high-speed cutting A C-axis unit for a machine tool, the C-axis unit comprising a bushing (134) adapted to be fixed to a unit support (121) of the machine tool; a head mounting platform (130) adapted to receive an operating head (40), the head mounting platform being supported by the bushing (134) and being rotatable relative to the bushing (134) around a vertical axis; a platform rotation motor (150) supported by the bushing (134) and configured to control the rotation of the head mounting platform (130); and a spindle motor (160) configured to control the rotation of a tool-carrying spindle (45) on the operating head (40) through a driving extension (163) arranged in a through-bore (133) obtained through the head mounting platform (130). The spindle motor (160) is fixed to and is rotationally integral with the head mounting platform (130).
US11559859B2	Weld coupon destructive test device A weld coupon destructive test device includes a support base. A plunger connected to the support base and movable between a first position and a second position along a length of the support base. A handle to operate the plunger between the first position and the second position. A header on the support base, the header configured to press a weld coupon between the header and the plunger, the header having a first support end and a second support end, the header having a depression formed between the first support end and the second support end. The weld coupon rests between the first support end and the second support end of the header, and the weld coupon is pressed into the depression formed between the first support end and the second support end of the header.
US11559858B2	System and method for creation of a predetermined structure from a diamond bulk Aspects of the invention may be directed to a method of creating a predetermined structure from a diamond bulk. In some embodiments, the method may include: irradiating the diamond bulk with at least one laser having a focal point at a predetermined location, the laser may create graphitization at locations where the focal point of the laser engages the diamond bulk; at least one of: moving the diamond bulk to be positioned with the focal point of the laser within the diamond bulk, and moving the at least one laser such that diamond bulk be positioned with the focal point of the laser, along at least one axis wherein the movement corresponds to a predefined scheme; removing of the graphite from the diamond bulk; and extracting the predetermined structure from the diamond bulk.
US11559848B2	Method for weld performance validation Methods are provided for joint performance validation and include preparing a coupon from a blank by bending the blank to have a pair of legs disposed at substantially ninety degrees relative to each other. Another coupon is prepared by forming an opening in a segment of another blank and bending the segment approximately ninety degrees. The segment is disposed adjacent an end of the second blank. A test sample is prepared by joining the coupons together at a joint with a leg attached to the segment approximately at a center of the leg. The test sample is subjected to a force test to generate data for the performance validation.
US11559844B2	Whirling tool A whirling tool for machining a workpiece, having: three or a multiple of three cutting plates, wherein each of the cutting plates comprises at least one cutting edge; a cutting plate holder having a plurality of cutting plate receptacles, wherein each of the cutting plate receptacles is configured to receive one of the cutting plates, wherein the cutting plate receptacles are disposed so as to be distributed in a circumferential direction across the cutting plate holder; and a plurality of fastening elements for releasably fastening the cutting plates in the cutting plate receptacles of the cutting plate holder; wherein the cutting plates comprise at least two different kinds of cutting plates, wherein at least one cutting plate of a first kind, and one cutting plate of a second kind are provided for each group of three cutting plates that are disposed beside one another on the cutting plate holder, wherein the cutting plate of the first kind differs from the cutting plate of the second kind by an overall geometry, by a dimension of the at least one cutting edge, and by a shape of the at least one cutting edge.
US11559840B2	Hole saw A hole saw includes a cylindrical body having a sidewall with a first end and a second end opposite the first end. The cylindrical body includes a gullet formed in the sidewall between a leading surface, a trailing surface, and a bottom surface of the sidewall. The gullet defines a central longitudinal axis extending between the first and second ends of the sidewall that is obliquely oriented relative to a rotational axis of the hole saw such that the gullet is angled from the first end to the bottom surface in a direction toward a cutting direction of the hole saw. The gullet has a dimension measured parallel to the rotational axis between the first end of the sidewall and the bottom surface of the gullet that is greater than 1.5 inches. The hole saw includes a cutting tooth coupled to the first end of the sidewall adjacent the gullet.
US11559839B2	Method and apparatus for producing nanoscale materials A method of producing nanoscale materials comprising the steps of entraining liquid droplets containing at least one nanoparticle precursor within a gaseous stream, and passing said gaseous stream containing said liquid droplets through a non-thermal equilibrium plasma whereby said plasma interacts with said at least one nanoparticle precursor to produce nanoparticles within said droplets without substantial evaporation of the droplets and conveying the thus produced nanoparticles within said gaseous stream downstream of said plasma.
US11559837B2	System and method for powder manufacturing A powder production method includes providing an elongated workpiece and repeatedly contacting an outer surface of the elongated workpiece with a reciprocating cutter according to a predetermined at least one frequency to produce a powder. The powder includes a plurality of particles, wherein at least 95% of the produced particles have a diameter or maximum dimension ranging from about 10 μm to about 200 μm. A system for producing powders having a plurality of particles including a cutter and at least one controller is also provided herein.
US11559830B2	Roll stand having a hybrid cooling device A roll stand (1) for rolling flat rolling stock (2) includes an upper working roller (3) and a lower working roller (4) that form a roll gap (5) between each other. The flat rolling stock (2) runs through the roll gap (5) in a transport direction (x) during rolling of the flat rolling stock (2). An upper cooling device (8), cools the upper working roller (3) and is arranged on the outlet side of the roll stand (1). The upper cooling device (8) has an upper spray boom (17), which extends parallel to the upper working roller (3) and has a plurality of upper spray nozzles (22), which spray a liquid coolant (12) onto the upper working roller (3). The upper cooling device (8) also has a lower spray boom (18), which extends parallel to the upper working roller (3) and has a plurality of lower spray nozzles (23), which spray the liquid coolant (12) onto the upper working roller (3). The lower spray boom (18) is arranged between the flat rolling stock (2) and the upper spray boom (17). At least some of the upper spray nozzles (22) are flat jet nozzles, and at least some of the lower spray nozzles (23) are full jet nozzles.
US11559828B2	Plant product extraction apparatus A plant product extraction apparatus or extractor is provided for separating or grading fine particles from a larger portion of material, such as separating trichomes from a stalk or flower of a plant. The apparatus imparts a plurality modes or patterns of oscillations and vibrations to a particle separator or sieve that holds the plant matter. A motor drives a back and forth motion to a support platform supporting a sieve. The sieve is constrained by a retention tray that is supported by the support platform. Vibratory motors provide rapid shaking vibration through the retention tray to the sieve. Agitators may be placed inside of the sieve to facilitate the separation of the plant materials. The various motors and locomotion patterns facilitate the separation of finer plant materials from a larger portion of a plant.
US11559827B2	Microfabricated ultrasonic transducer having individual cells with electrically isolated electrode sections An ultrasonic transducer includes a membrane, a bottom electrode, and a plurality of cavities disposed between the membrane and the bottom electrode, each of the plurality of cavities corresponding to an individual transducer cell. Portions of the bottom electrode corresponding to each individual transducer cell are electrically isolated from one another. Each portion of the bottom electrode corresponds to each individual transducer that cell further includes a first bottom electrode portion and a second bottom electrode portion, the first and second bottom electrode portions electrically isolated from one another.
US11559825B2	Gravitational method for assembling particles A method for assembling particles on a microstructured surface of a sample. The method includes a step of covering the surface of the sample with a colloidal suspension with a so-called covering temperature range. The method includes a step of sedimentation of particles contained in the colloidal suspension such that particles settle towards the surface of the sample, the sedimentation step being carried out within a so-called sedimentation temperature range.
US11559823B2	Volumetric measurement and regulation device incorporated in a time-pressure dispenser A device for measuring and regulating a volume of a fluid dispensed by a time-pressure dispenser, the device comprising: an adaptor for releasably coupling a syringe to the device, the syringe containing a fluid to be dispensed; a probe configured to be coupled with a piston of the syringe, the piston being operative to apply a pressure for ejecting the fluid from the syringe upon the application of an air pressure to the piston; and a displacement detector operative in use to determine a position of the probe so as to determine a position of the piston when dispensing the fluid, whereby to regulate the volume of the fluid dispensed from the syringe.
US11559822B2	Cosmetic container having retractable button Provided is a cosmetic container having a retractable button including: a container body filled with contents; a pump part arranged on the upper portion of the container body in order to discharge the contents externally through a pumping action; and a button part arranged on the upper portion of the pump part to make the pumping action carried out by the user's pressing and releasing action, the button part having a discharge part to discharge the contents externally, wherein the button part has an inhalation space formed inside the button part, and the inhalation space is communicated with the discharge part, is increased or decreased in volume according to pressurization and release of the button part in order to inhale the contents remaining in the discharge part.
US11559818B2	Cell washing device and method A cell washer is disclosed. The cell washer includes a vessel configured to hold cells. The vessel includes an elongated body including an opening, an inner surface, and a pocket defined by a first inner surface portion of the inner surface disposed between and radially outward relative to a second inner surface portion and a third inner surface portion of the inner surface, and a cavity. The vessel also includes an actuating device capable of causing the vessel to spin about an axis.
US11559816B2	System and a process to determine online the characteristics of expended balls and the stitches of the same, which have been expulsed from a semiautogen mineral grinding mill The invention relates to the field of operating, monitoring and controlling mills of the mining industry. It specifically relates to a system and a method for in-line determination of the characteristics of worn balls and pieces thereof, which have been ejected from a semi-autogenous mineral grinding (SAG) mill to the external classifiers.
US11559812B2	Apparatus for multi-specimen test instrument Described are a test device, a multi-specimen test fixture star and a multi-specimen test fixture. The test device includes a bath chamber that is automatically replenished with bath liquid throughout an extended test period. The multi-specimen test fixture star is non-circularly symmetric and can be used, for example, in a rectangular bath chamber to hold a greater number of test specimens than a circularly symmetric test fixture star. The multi-specimen test fixture includes, in part, a multi-specimen test fixture star and a shaft having one or more keyways and enables the test fixture star to be repositioned along the shaft without loss of rotational alignment to the shaft.
US11559811B2	Cell culture system and method A bioprocess system and a method for incubating, growing and harvesting cell cultures is described. Also disclosed is a bioprocess container that can be used with the system. In one aspect of the present disclosure, the bioprocess system includes bioprocess tubes and cell culture tubes having particular dimensions and being made from specific materials that allow the tubes to be welded together while preventing open connections and/or ruptures. In this manner, bioprocess containers can be connected and disconnected from a cell culture apparatus without having to perform the manipulation within a closed environment and without associated monitoring.
US11559808B2	Microfluidic device A microfluidic device includes a lower casing and an upper casing covering the lower casing. The lower casing includes a lower base wall having a top surface and a plurality of spaced-apart columns that protrude upwards from the top surface. The upper casing includes an upper base wall. A first gap between the upper base wall and a column top surface of each of the columns is large enough to permit passage of large biological particles of a liquid sample, and a second gap between any two adjacent ones of the columns is not large enough to permit passage of the large biological particles and is large enough to permit passage of small biological particles of the liquid sample.
US11559805B2	Systems, methods, and apparatuses to image a sample for biological or chemical analysis A fluidic device holder configured to orient a fluidic device. The device holder includes a support structure configured to receive a fluidic device. The support structure includes a base surface that faces in a direction along the Z-axis and is configured to have the fluidic device positioned thereon. The device holder also includes a plurality of reference surfaces facing in respective directions along an XY-plane. The device holder also includes an alignment assembly having an actuator and a movable locator arm that is operatively coupled to the actuator. The locator arm has an engagement end. The actuator moves the locator arm between retracted and biased positions to move the engagement end away from and toward the reference surfaces. The locator arm is configured to hold the fluidic device against the reference surfaces when the locator arm is in the biased position.
US11559803B2	Microfluidic chip for analysis of cell motility and methods for using same The present invention describes an integrated apparatus that enables identification of migratory cells directly from a specimen. The apparatus only requires a small number of cells to perform an assay and includes novel topographic features which can reliably differentiate between migratory and non-migratory cell populations in a sample. Both the spontaneous and chemotactic migration of cancer cells may be measured to distinguish between subpopulations within a tumor sample. The migratory cells identified using the apparatus and methods of the present invention may be separated and further analyzed to distinguish factors promoting metastasis within the population. Cells in the apparatus can be treated with chemotherapeutic or other agents to determine drug strategies to most strongly inhibit migration. The use of optically transparent materials in some embodiments allows a wide range of imaging techniques to be used for in situ imaging of migratory and non-migratory cells in the apparatus. The apparatus and methods of the present invention are useful for predicting the metastatic propensity of tumor cells and selecting optimal drugs for personalized therapies.
US11559798B2	Process for production of attrition stable granulated material The present invention relates to granulated particles with improved attrition and a method for producing granulated particles by fluidized bed granulation of inorganic particles wherein particles of reduced particle size are fed into a fluldized-bed granulation reactor thereby producing granulated particles with improved attrition.
US11559793B2	Perovskite catalysts and uses thereof The present disclosure provides perovskite catalytic materials and catalysts comprising platinum-group metals and perovskites. These catalysts may be used as oxygen storage materials with automotive applications, such as three-way catalysts. They are also useful for water or CO2 reduction, or thermochemical energy storage.
US11559791B2	Carbon-doped nickel oxide catalyst and methods for making and using thereof A catalyst composition including nickel foam and a plurality of carbon-doped nickel oxide nanorods disposed on the nickel foam.
US11559790B2	Reconstituted dehydrogenation catalyst showing slowed activity loss when compared with fresh catalyst A process for dehydrogenating alkane or alkylaromatic compounds comprising contacting the given compound and a dehydrogenation catalyst in a fluidized bed. The dehydrogenation catalyst is prepared from an at least partially deactivated platinum/gallium catalyst on an alumina-based support that is reconstituted by impregnating it with a platinum salt solution, then calcining it at a temperature from 400° C. to 1000° C., under conditions such that it has a platinum content ranging from 1 to 500 ppm, based on weight of catalyst; a gallium content ranging from 0.2 to 2.0 wt %; and a platinum to gallium ratio ranging from 1:20,000 to 1:4. It also has a Pt retention that is equal to or greater than that of a fresh catalyst being used in a same or similar catalytic process.
US11559785B2	Method for separation of radioactive sample using monolithic body on microfluidic chip The present invention relates to monolithic bodies, uses thereof and processes for the preparation thereof. Certain embodiments of the present invention relate to the use of a monolithic body in the preparation of a radioactive substance, for example a radiopharmaceutical, as part of a microfluidic flow system and a process for the preparation of such a monolithic body.
US11559782B2	Reactive media Various embodiments of the present invention relate to reactive media including calcium. A reactive media includes a vitrified calcium silicate comprising reactive calcium. Various embodiments of the reactive media described herein are useful for removal of anionic impurities such as phosphate from water.
US11559769B2	Nanocarbon separation device and nanocarbon separation method A nanocarbon separation device includes a first porous structure configured to hold a solution containing a surfactant, a second porous structure configured to hold a dispersion medium, a holding part provided between the first porous structure and the second porous structure and configured to hold the dispersion liquid containing the nanocarbons and the surfactant and having a smaller content of the surfactant than that of the solution, a separation tank in which the first porous structure, the holding part and the second porous structure are disposed and accommodated in an order of the first porous structure, the holding part and the second porous structure, a first electrode provided on a lower section of the first porous structure, and a second electrode provided on an upper section of the second porous structure.
US11559763B2	Regenerable solvent mixtures for acid-gas separation A solvent system for the removal of acid gases from mixed gas streams is provided. Also provided is a process for removing acid gases from mixed gas streams using the disclosed solvent systems. The solvent systems may be utilized within a gas processing system.
US11559762B1	Heat pump-based water harvesting systems, and methods of using thereof Provided herein are water harvesting systems, as well as methods of making and using such systems, for capturing water from surrounding air using a design that reduces overall energy costs of the systems and improve water harvesting cycle efficiency. The systems and methods use sorbent materials, such as metal-organic frameworks, to adsorb water from the air. The systems and methods desorb this water in the form of water vapor, and the water vapor is condensed into liquid water and collected. The liquid water is suitable for use as drinking water.
US11559760B2	Grounded filter regulator lubricator A grounded FRL for treating a pressurized air supply has a housing with a connecting mechanism for connecting to a collector bowl. The collector bowl is made from a metal base material and has an open end with a connecting mechanism and a closed distal end. The housing has a flange that is electrically conductive and extending downwardly at an exterior of the bowl. At least one grounding clip member is made from electrically conductive material and has an exterior mounting end attached to the flange for electrical connectivity thereto and has a radially inner end that electrically makes contact with the metal base materials of the collector bowl and the housing.
US11559755B2	Vortex reservoir A vortex reservoir for separation of an aerated portion of a hydraulic fluid includes an upper chamber and a lower chamber, in fluid communication with the upper chamber, having a lower chamber sidewall. The lower chamber includes a lower lower chamber and an upper lower chamber. The lower chamber includes a lower chamber partitioning plate. The lower chamber partitioning plate is located between the lower lower chamber and the upper lower chamber. The lower lower chamber is in fluid communication with the upper lower chamber via a gap between the lower chamber partitioning plate and the lower chamber sidewall.
US11559753B2	Isolating components from plants The invention relates to methods of separating or isolating a component from a plant using freeze separation. The invention includes products produced by said methods.
US11559749B2	Systems and methods for thrust-vectored practical fluid flow effects An amusement park attraction effects system includes a dynamic display for viewing by a user traveling through an attraction, a display monitor to provide status data indicative of a status of the dynamic display, a location identification system to determine a location of the user, a thrust-vectoring flow effect generator to generate and direct a fluid flow toward any particular target location of a range of target locations, and an automation controller communicatively coupled to the display monitor, the location identification system, and the thrust-vectoring flow effect generator. The automation controller is configured to receive the status data, receive the location of the user, set a target location based on the location of the user, instruct the thrust-vectoring flow effect generator to direct the fluid flow based on the target location, and instruct the thrust-vectoring flow effect generator to control the fluid flow based on the status data.
US11559744B2	Targeting of an individual object among a plurality of objects in a multi-player online video game Systems, methods, and media are provided for improved targeting of an individual object among a plurality of objects in a multi-player online video game. The video game may include plurality of objects located at various places at a given frame. At each frame, a position of the objects is identified. If a player object (except for the player object associated with the user) is within a predetermined radius of another player object, a target position of the player object is modified relative to other player objects. Next, the target position of the player object is modified towards its original position within the frame. This process is repeated for each player object until the corresponding player object is no longer within the predetermined radius of another player object or a violation of a constraints prevents the modification from being performed.
US11559739B2	Storage medium having stored therein game program, game apparatus, game system, and game processing method In a second mode where a first enemy object attacks a player object in a virtual space, no matter which of a switching condition that a second time elapses and a switching condition that the player object gains a second required number of target objects smaller than a first required number before the second time elapses is satisfied, a game mode is switched to a first mode where the first enemy object does not attack the player object.
US11559737B2	Video modification and transmission using tokens Methods and apparatus are disclosed for video transmission using tokens. According to one example, computer-readable storage media store instructions that cause a processor to: distribute, toward terminal devices of a plurality of viewers via a communication line, motion data or a first video including an animation of an avatar of a distributor generated on the basis of the motion data; distribute, toward the terminal devices of the plurality of viewer via the communication line, a second video related to a computer-implemented game generated on the basis of operation data by using a received web page; receive, via the communication line, token data indicating that any type of token among a plurality types of tokens is given to the distributor, the token data being generated by the terminal device of each viewer viewing the second video; calculate a score based on the total number of at least one type of tokens given to the distributor using the token data; and control a game object used in the game on the basis of the score.
US11559731B2	Portable instructional baseball pitching apparatus An apparatus for teaching baseball pitching includes a substantially flat panel having a substantially rectangular shape with adjustable height and width dimensions. The apparatus further includes at least two support members for supporting the flat panel in an upright position. The length of the support members can be adjusted to obtain a desired distance between a bottom edge of the flat panel and the ground.
US11559730B2	Sports equipment with alterable characteristic Articles of sports equipment, such as striking implements (e.g., sticks) and wearable articles (e.g., skates, helmets) for playing hockey or other activities, in which at least one of the characteristics (e.g., stiffness) of the articles of sports equipment is adaptable and can be altered during use of the sports equipment, such as by comprising an alterable component coupled to a controller, by comprising an alterable component that is autonomously alterable, and/or by an alterable component that can be altered in response to a command of a remote device.
US11559729B2	Club head with sole mass element and related method Embodiments of a golf club head comprising a club head body and a sole mass element are described herein. The club head comprises a center of gravity height measured between a club head center of gravity and at least one keel point. The club head comprises a face surface, wherein the face surface defines a face height. The club head defines a ratio of club head center of gravity height to face height, wherein the ratio is less than or equal to approximately 0.36.
US11559727B2	Golf club head Disclosed herein is an iron-type golf club head that comprises a body, made of a first material having a first density. The iron-type golf club head also comprises a weight located within the internal cavity. The iron-type golf club head further comprises a filler material that has a density no less than 0.21 g/cc. The filler material has a mass no less than 2.5 grams and no more than 8 grams. The internal cavity has an internal cavity volume ranging between 5 cc to 20 cc. A ratio of the internal cavity volume to external club head volume ranges between 0.14 and 0.385. The internal cavity has a minimum front-to-back depth above a midplane of the golf club head of no less than 1.4 mm and a maximum front-to-back depth of the internal cavity above the midplane of the golf club head is no more than 13 mm.
US11559726B2	Grooves of golf club heads and methods to manufacture grooves of golf club heads A golf club head including a club face defined by a toe end, a heel end, a top rail and a sole. The golf club head including a plurality of grooves disposed on the club face between the top rail and the sole. Each groove extends between the toe end and the heel end. Depths of the grooves vary in a direction extending between the top rail and the sole and in a direction extending between the heel end and the toe end. Widths of each of the plurality of grooves vary in a direction extending between the heel end and the toe end.
US11559723B2	Combined oscillating positive expiratory pressure therapy and Huff Cough simulation device A respiratory treatment device including an OPEP (oscillating positive expiratory pressure) mechanism, a Huff Cough mechanism, a user interface, and a conduit leading from the user interface to the OPEP mechanism and the Huff Cough mechanism, wherein air flow through the conduit is selectively directed to the OPEP mechanism and the Huff Cough mechanism.
US11559714B1	Piercing pipe fire suppression system A method and system are provided for an unmanned sprinkler system for suppressing fires that includes one or more hoses, one or more pipes, and a plurality of piercing nozzles arrayed and extending downward along each of the one or more pipes. Each of the piercing nozzles comprise a plurality of water flow openings for providing a sprinkler effect that suppresses or extinguishes fires.
US11559712B2	Hermetically sealed portable fire extinguisher with pressure indicator A portable fire extinguisher is disclosed which includes a cylinder for storing a pressurized fire extinguishing agent and has a neck portion defining an outlet, and a flexible hermetic seal supported across the outlet of the cylinder, wherein the flexible hermetic seal is adapted and configured to transition between: an unexpanded condition corresponding to an unpressurized cylinder; an expanded condition corresponding to a pressurized cylinder; and a bursted condition corresponding to an opened cylinder.
US11559709B2	Receptacle for suppressing and containing a fire The present invention is a shipping container adapted to isolate and extinguish a fire within the container, the container comprising a container body having a bottom, an interior wall defining an internal region, an opening into the internal region, a cover positionable over the opening, an insert or liner provided within the container and at a fixed distance from its interior wall, the insert having apertures extending therethrough, the region between the container's interior wall and bottom and the insert containing a free-flowing expanded glass granulate having fire insulating, fire suppressing and smoke absorbing properties.
US11559707B2	Oxygen candle Provided is an oxygen candle starting device, comprising a pull line column (17) and a percussion cap (15), wherein a pull line hole (155) is provided in the pull line column in an axial direction of the pull line column, a percussion cap cavity (154) is provided inside one end of the pull line column, a fire-preventing cavity is provided inside the other end of the pull line column, and the pull line hole passes through the fire-preventing cavity and the percussion cap cavity; the percussion cap is mounted in the percussion cap cavity, and sand grains (16) are packaged in the fire-preventing cavity. Further provided is an oxygen candle comprising the oxygen candle starting device and an oxygen generator, wherein the oxygen generator comprises an agent loading housing, with a through hole being provided in the top of the agent loading housing, a gas outlet being provided in the bottom thereof, and a filter being mounted at the gas outlet; and the percussion cap of the oxygen candle starting device is in contact with an oxygen candle agent via the through hole, the oxygen generator is connected to the agent loading housing in a sealed manner, and the filter is connected to the gas outlet in a sealed manner. The oxygen candle employs a pull-type starting device, and the starting structure for an existing oxygen candle is simplified, thereby preventing a false start caused by the falling-off of a steel needle and improving the reliability.
US11559702B2	Charged particle treatment planning system with PBS beamlets sequence optimized for high dose deposition rate A treatment planning system for generating a plan for treatment by radiation with charged particles beams applied by pencil beam scanning onto a target tissue comprising tumoral cells is provided. The treatment planning system performs a dose definition stage defining the doses to be deposited within the peripheral surface, a beam definition stage defining positions and dimensions of the beamlets of the PBS during the at least one high rate fraction, the beams definition stage including a dose rate definition stage comprising at least one high rate fraction, and a beamlets scanning sequence stage defining a scanning sequence of irradiation of the beamlets. The beamlets scanning sequence stage optimizes a time sequence of beamlets emission such that at the end of a fraction j, a dose is deposited onto at least a predefined fraction of each specific volume at a mean deposition rate superior or equal to a predefined value.
US11559694B2	Methods of manufacturing a hermetic lead connector A method of manufacturing a hermetic lead connector includes fixing an electrically insulating ring between an electrically conducting contact ring and an electrically conducting spacer ring to form a hermetic ring subassembly, and fixing a plurality of the hermetic ring subassemblies in axial alignment to form a hermetic lead connector. The hermetic lead connector includes an open end, an outer surface, and an inner surface defining a lead aperture. The hermetic lead connector provides a hermetic seal between the outer surface and the inner surface.
US11559693B2	Pairing of external communication devices with an implantable medical device via a patient remote controller Techniques for pairing an external device such as a clinician programmer (CP) to an implantable medical device (IMD) are disclosed, which involve use of a remote controller (RC) paired to the IMD. The RC is placed into a CP pairing mode, which acts differently depending on the type of IMD paired to the RC. If the IMD is RF based, the CP pairing mode places the IMD in a pairing mode, thus allowing the CP to connect directly with the IMD via a RF telemetry protocol. If the IMD is magnetic-induction based, the CP pairing mode causes the RC to advertise its presence to the CP, allowing the CP to connect to the RC via the RF telemetry protocol. Because the RC is also paired with the IMD via a magnetic induction telemetry protocol, the RC acts as a passthrough device to allow communications between the CP and the IMD.
US11559692B2	Electrode devices for neurostimulation An extravascular neural interface is disclosed containing electrodes for neurostimulation of the vessel. The devices are housed in flexible substrates, each substrate having a spinal portion for routing leads/conductors into the device for connection to the electrodes. Extending from opposite sides of the spinal portion is a self-sizing inner flap that supports and positions the electrodes to be inward facing, i.e., extravascular designs, and one more rigid outer flap. The electrodes may be flexible multifilar coil electrodes.
US11559690B2	Ventricular assist system and method Various embodiments of a ventricular assist system and a method of using such system are disclosed. The system includes a pump adapted to be connected to a heart of a patient, an outflow cannula including a first end adapted to be connected to an outlet of the pump and a second end adapted to be connected to an artery of the patient, and an electrode disposed on an outer surface of the outflow cannula and adapted to be disposed adjacent to an exterior wall of the heart. The system further includes a controller electrically connected to the pump and the electrode, where the controller is adapted to provide a pacing signal to the electrode.
US11559689B2	Noise detection and modulation of closed-loop therapy action A medical device with closed-loop responsive stimulation may include techniques to mitigate the impact on the therapy output of noise coupled into the medical device. A medical device according to this disclosure may determine the presence of noise and alter the closed loop policy to provide the necessary therapy to the patient and avoid prolonged under stimulation caused by the noise. The medical device may continue therapy while testing for noise. When the device determines the noise level no longer affects the output therapy, the device may return the closed loop policy to a no-noise mode of operation. The medical device may also include techniques to mitigate the impact of manual adjustment while the medical device is subject to noise or is responding to changes in the patient's physiological signals.
US11559685B2	Modular neurological screening adapter system for intraoperative testing and patient-worn trialing An adapter system connects to implantable electrode leads. The adapter system has the pulse generator configured to generate electrical stimulation pulses and has a first connector member. The adapter has a housing containing two receptacles. Each receptacle receives an end portion of an electrode lead to establish an electrical connection between the adapter and the electrode lead. The adapter contains a second connector member configured to engage with the first connector member to establish a mechanical connection between the housing and the pulse generator and an electrical connection between the pulse generator and the electrode lead. A test cable electrically connects the pulse generator to the electrode leads for testing the electrode leads. The test cable contains a first connector member configured to engage with the second connector member to establish an electrical connection. The test cable contains a second connector member configured to engage with the first connector member.
US11559684B2	Photosensitive array The present invention relates to photosensitive arrays comprising a plurality of photosensitive elements disposed in or on a suitable substrate. The photosensitive arrays are useful as implants, in particular as retinal implants. Methods for manufacturing such arrays are also provided.
US11559682B2	Method and device for providing stimulation to a cochlea A cochlear implant includes an electrode array having a plurality of electrode contacts arranged along at least a portion of a length of an electrode array, and a processing arrangement configured to map at least one electrode contact to first and/or second mappings. The first mapping provides a first electrical stimulation from the electrode contact to a first ground electrode positioned external to a patient's cochlea to stimulate hearing at a first location in the cochlea positioned adjacent to the electrode contact when the implant is inserted into the cochlea. The second mapping provides a second electrical stimulation from the electrode contact to the second ground electrode to stimulate hearing at a location in the cochlea positioned further towards the apex of the cochlea as compared to a distal end of the electrode array when the implant is inserted into the cochlea.
US11559678B2	Adhesive electrode for the registration of electric signals An adhesive electrode for the registration of electric and electrobiological signals and/or for stimulating a patient includes a patient contact portion and a transmission portion. The patient contact portion includes a layer of adhesive electrolyte material in contact with the patient's skin, a layer of conductive material, and a layer of insulating material. The transmission portion is also connected to the conductive layer. The layer of conductive material includes at least partially a layer of magnetic material, the transmission portion being removably secured to the layer of magnetic material.
US11559674B2	Fluid delivery apparatus and method of assembly A fluid delivery apparatus includes a collet assembly having an upper and lower wall attached at a central portion of the collet. The central portion defines an inner step, and the lower wall includes circumferentially-spaced flexible tabs. The fluid delivery apparatus also includes a fluid distribution assembly coupled to the collet assembly. The fluid distribution assembly is positionable relative to the collet between a pre-use configuration and a pre-activated configuration. The fluid distribution assembly has a plenum that includes a sleeve component having an exterior ledge extending thereabout. A lower wall portion of the sleeve component includes protrusions corresponding to the flexible tabs of the collet. In the pre-use configuration the exterior ledge of the sleeve component is engaged with the inner step of the collet assembly, and each flexible tab engages a respective protrusion to provide a snap-fit between the fluid distribution assembly and the collet assembly.
US11559664B2	Instrument for endoscopic applications An instrument (203; 204) for endoscopic applications. The instrument is able to be guided through a curved shaped tube (201; 202) and has an intermediate cylindrical element (3) with a handling end portion with a flexible portion and actuating means located at an actuating end portion. The intermediate cylindrical element (3) has a first cylindrical part (31; 151) at the handling end portion, a second cylindrical part (35; 155) at the actuating end portion and a number of longitudinal elements (38; 60; 70; 80; 90; 100; 110; 130; 153) for transferring the movement of the actuating means to the handling end portion. The longitudinal elements are separated by longitudinal slits in the intermediate cylindrical element.
US11559662B2	Steerable drainage devices Steerable, elongated medical devices that are inserted into a patient's body are disclosed. The devices include first and second wires slidably extending longitudinally through a wall of a tube and attached adjacent a distal end of the tube. The devices also include a tension control member configured to selectively apply a tension force to the wires to bend the tube.
US11559659B2	Medical device for puncturing A medical device includes: a tube through which fluid flows; a handle part coupled to a proximal end part of the tube; an electrode tip coupled to a distal end part of the tube; a fluid injection part configured to inject fluid into the tube; one or more openings formed in the tube; and a guide member disposed in the tube, and having an inclined part to guide the direction of the fluid sprayed out through the opening.
US11559655B2	Dual container hydrostatic ventilator In an example, a ventilator includes a first container and a second container in fluidic communication with each other via a liquid. The second container includes a second container space surrounded by the second container and a second liquid surface. A hydrostatic pressure in the second container space results from a pressure differential defined by a difference between the first liquid surface elevation in the first container and the second liquid surface elevation. The second container space increases in size with an increase in the breathing gas supplied from a gas supply line to the second container space. An inhalation line is configured to open to permit a flow of the breathing gas from an inhalation inlet in the second container space to an inhalation outlet outside of the liquid and outside of the second container and coupled to a patient, causing the second container space to decrease in size.
US11559652B2	Oxygen delivery apparatus using eyeglass frames An oxygen delivery apparatus wearable by user includes a frame including nose pads connected to a bridge portion, an oxygen inlet defined by one of the nose pads, an oxygen inlet defined by the frame, and a hollow channel contained by the frame. The oxygen inlet and oxygen outlet are in fluid communication via the hollow channel. The frame can be formed as a monolithic structure using additive manufacturing. A nasal prong can be connected to the oxygen outlet such that a prong outlet of the prong is in fluid communication with the hollow channel. The prong outlet is positioned within a nostril of the user during use of the apparatus. A method of fabricating the frame includes obtaining measurement information for at least one of a head feature or facial characteristic of the user and generating a digital model of the oxygen delivery apparatus using the measurement information.
US11559649B2	Support member for cushion of respiratory interface device A support member for use in a sealing assembly of a patient interface device for delivering a flow of a breathing gas to the airway of a patient. The support member includes: a first end structured to be coupled to a frame member of the patent interface device; a second end structured to sealingly engage the face of a patient or to underlie a sealing flap which is structured to sealingly engage the face of a patient; and a sidewall which extends between the first end and the second end. The sidewall is formed from a plurality of beads of material.
US11559644B2	Process and adjusting device for adjusting a ventilation parameter as well as medical system A process adjusts a ventilation parameter (40) for a ventilation process (90) of a patient (110), which is carried out by a ventilator (20). Electrical impedance tomographic (EIT) data (70) of the lungs (111) of the patient (110), concerning the ventilation process (90), are collected by an EIT device (30). An adjusting device (1), adjusting a ventilation parameter (40) for the ventilation process (90), has an analysis unit (2) with a memory (3), a data input unit (5) data-communicatingly connected to the analysis unit (2) for receiving data and a data output unit (7) data-communicatingly connected to the analysis unit (2) for outputting data. A medical system (100), includes a ventilator (20), an EIT device (30) as well as the adjusting device (1) for adjusting a ventilation parameter (40) for the ventilation process (90) of a patient (100).
US11559641B2	Methods and systems for managing a patient move This disclosure describes systems and methods for managing a move of a patient being monitored or treated by a medical system, such as a medical ventilator. The disclosure describes a novel approach for preventing a patient from being moved from a first location to second different location that is connected to a monitoring and/or treatment system, before all of the necessary hoses have been disconnected from the patient. Further, the disclosure describes a novel approach of ensuring that all of the necessary hoses are reconnected to a patient being monitored or treated by a monitoring and/or treatment system after being moved from the first location to the second different location.
US11559631B2	Safety needle device A safety needle device is disclosed having a housing configured to couple to a syringe, the housing having a proximal end, a distal end, and a housing body. A first guide path, a second guide path and a third guide path may be disposed on the housing body. A needle hub is disposed on the proximal end of the housing and a needle cannula is attached to the needle hub. The device having a retractable sheath configured to move between an initial position, a retracted position and an extended position with respect to the housing, wherein the initial position partially exposes a distal tip of the needle cannula, the retracted position fully exposes the needle cannula, and the extended position fully covers the distal tip of the needle cannula. The retractable sheath also may have a guide element. The first, second and third guide paths are configured to slidingly receive the guide element. The device also having a first locking member, a second locking member, a rotating cam disposed in the housing body, and a spring element to bias the retractable sheath to an extended state to cover the distal end of the needle cannula upon completion of an injection.
US11559630B2	Auto-Injector An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case, a carrier subassembly comprising a tubular carrier slidably arranged inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector also has, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for advancing the needle beyond a proximal end of the auto-injector, and a trigger button is used for releasing the control spring on actuation.
US11559626B2	Means to treat Alzheimer's disease via flushing of brain parenchyma An implantable glymphatic pump configured to flush metabolites from a brain parenchyma of a patient. The implantable glymphatic pump including at least one spinal catheter having a distal end configured to be positioned within an intrathecal space of a spine of a patient, at least one cranial catheter having a distal end configured to be positioned within a brain parenchyma of the patient, and an implantable pump configured to draw cerebrospinal fluid from the intrathecal space of the spine in the patient via the at least one spinal catheter, and reintroduce said cerebrospinal fluid to the brain parenchyma of the patient via the one or more cranial catheters to encourage a flow of the cerebrospinal fluid through the brain parenchyma.
US11559624B2	Systems for wearable infusion port and associated pump A wearable infusion port for infusing a fluid includes a first housing that defines an inlet port to receive the fluid, and a second housing coupled to the first housing. The second housing is to be coupled to an anatomy. The wearable infusion port includes a valve assembly fluidly coupled to the inlet port, and the valve assembly is movable from a closed state to an opened state to dispense the fluid. The wearable infusion port includes a cannula assembly extending through the first housing and the second housing, and the cannula assembly includes a cannula fluidly coupled to the valve assembly. The cannula is to be coupled to the anatomy. The wearable infusion port includes a flow sensor fluidly coupled to the inlet port and the cannula. The flow sensor is fluidly coupled upstream from the cannula to observe an amount of fluid received by the cannula.
US11559620B2	Canister status determination A method and apparatus are disclosed for determining status of a canister of a topical negative pressure (TNP) system. The method includes the steps of monitoring pressure provided by a pump element of the TNP system, determining at least one characteristic associated with the monitored pressure and determining status of at least one parameter associated with a canister of the TNP system responsive to the determined characteristics.
US11559618B2	Formulations and methods for direct sodium removal in patients having severe renal dysfunction A direct sodium removal (“DSR”) infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and/or heart failure, in which a patient has at least a first DSR session with a first DSR infusate having no or low sodium that is instilled into a patient's peritoneal cavity for a first dwell period to cause sodium and excess fluid to migrate to the patient's peritoneal cavity, and thereafter, the patient may undergo conventional dialysis to rebalance the patient's fluid and sodium levels.
US11559611B2	Medical device A medical device comprising a substantially flexible porous structure. The porous structure comprises a plurality of interlocking units. Each of the plurality of interlocking units comprises a body and at least one arm. The plurality of interlocking units is configured to have space between adjacent interlocking units when the porous structure is in a neutral configuration. The plurality of interlocking units is configured to contact the respective body and arm of adjacent interlocking units when a compressive force is applied to the porous structure, thereby restricting compression of the porous structure. The plurality of interlocking units is configured to contact the respective arms of adjacent interlocking units when an extension force is applied to the porous structure, thereby restricting extension of the porous structure.
US11559609B2	Bone-promoting thermoresponsive macromolecules Provided herein are injectable, thermoresponsive hydrogels that are liquid at room temperature, provide a carrier material, and gel at body temperature to allow for controlled release. In particular, PPCN-based hydrogels are provided with therapeutic agents (e.g., drugs, ions, etc.) incorporated within or appended thereto, and methods of preparation and use thereof, for example, for the promotion of bone formation/repair and/or the treatment of bone diseases.
US11559607B2	Living devices for replacement of organs or specific organ functions, methods and uses of the same Described are devices and methods for use in connection with organ replacement or organ assist therapy in a patient.
US11559606B2	Semi-synthetic tissue constructs for tissue regeneration Methods and compositions for tissue regeneration of the present invention include a biocompatible porous composite of a decellularized tissue and an aptamer-functionalized hydrogel, wherein the aptamers of the aptamer-functionalized hydrogel specifically and reversibly bind to an active agent.
US11559600B2	Decontamination reactor for fluid purification An apparatus for treating contaminated fluid has a UV lamp within an elongate housing, typically rectangular shaped. Deflector baffles within the housing create a meandering pathway perpendicular to the lamp for exposing the fluid to the UV light along the entire length of the pathway. Fins create multiple channels in the pathway to substantially increase internal surface area contact with the fluid. A photocatalytic coating on the baffles, fins and internal surfaces of the housing is maintained within a pre-set radial distance, preferably within about 75 mm, from the lamp for optimal creation of a photocatalytic reactant. The fluid flowing along the pathway, including channels, is also maintained in close proximity to the lamp and has adequate time for exposure to the ultraviolet light and photocatalytic reactant for treatment before exiting the housing. Baffles and fins are removably positioned within the housing for convenient maintenance, pathway length alteration or accommodating fluid volume flow adjustment, with little or no housing re-sizing. This apparatus is an affordable and compact environmental protection device capable of “air quality refinement”, especially for building ventilation systems, by mitigating the spread of harmful pathogens and/or toxic chemicals.
US11559599B2	Scent retaining structure, method of manufacturing the scent retaining structure, and scent providing device The present disclosure provides a perfume retaining structure, a method of manufacturing the perfume retaining structure, and a scent providing device that can reduce ventilation resistance of air that passes through a space in which a perfume retainer is arranged.The perfume retaining structure includes the perfume retainer, a retaining space in which the perfume retainer is arranged, and a first opening and a second opening that allow the retaining space to be opened to the outside. The retaining space has a ventilation area that faces the first opening and the second opening, and a retaining area that is arranged adjacent to the ventilation area and communicates with the ventilation area, and the perfume retainer is arranged in the retaining area.
US11559597B2	Medical device inspection system A medical device inspection system may include a base, a medical device holder on the base, a fiber scope holder on the base, a moveable roller moveably attached to the base such that it is free to rotate around an axis and move from a first position to a second position along the base, and a feeder coupled with the base for feeding a flexible portion of the fiber scope into a lumen of the medical device. During use, the flexible portion of the fiber scope may extend from the handle, around the moveable roller, and through the feeder to enter an opening in the lumen of the medical device.
US11559592B2	Sterilization structure, sterilization board and display device A sterilization structure, a sterilization board, and a display device are disclosed. The sterilization structure includes an active layer, wherein, one surface of the active layer has an exposed region, and a material of the active layer includes a laser-induced graphene material.
US11559591B2	Ultrasmall nanoparticles labeled with Zirconium-89 and methods thereof Described herein are nanoprobes comprising ultrasmall aminated and cRGDY-conjugated nanoparticles labeled with Zirconium-89 (89Zr) and methods of their use. The provided compositions are renally clearable and possess suitable blood circulation half-time, high tumor active targeting capability, dominant renal clearance, low liver accumulation, and a high tumor-to-background ratio. The described nanoprobes exhibit great potential as “target-or-clear” tracers to human subjects for systemic targeted imaging (or treatment) of cancer.
US11559590B2	Granzyme B directed imaging and therapy Provided herein are compounds useful for imaging granzyme B. An exemplary compound provided herein is useful as a radiotracer for position emission tomography (PET) and/or single photon emission tomography (SPECT) imaging. Methods of imaging granzyme B, combination therapies, and kits comprising the granzyme B imaging agents are also provided.
US11559587B2	RNA formulation for immunotherapy The present invention is in the field of immunotherapy, in particular tumor immunotherapy. The present invention provides pharmaceutical formulations for delivering RNA to antigen presenting cells such as dendrite cells (DCs) in the spleen after systemic administration. In particular, the formulations described herein enable to induce an immune response after systemic administration of antigen-coding RNA.
US11559586B2	Nanoparticles for treatment of choroidal neovascularization and other indications The present invention generally relates to particles such as nanoparticles and, in particular, to targeted nanoparticles. In some cases, the particles may have a targeting moiety that is inhibited from recognizing a target, for example, by being positioned within the particle at an internal location. The application of a stimulus, such as light, may allow the targeting moiety to interact externally of the particle. Accordingly, the particles may be targeted to specific locations using the application of a suitable stimulus. For instance, in one embodiment, particles containing cell-penetrating peptides attached via a first attachment and a second attachment containing a photocleavable entity may be administered to a subject, and light may be applied, e.g., to the eye, to cleave the photocleavable entity. However, despite the cleavage, the peptides remain associated with the particle via the first attachment, and thus, the particles may be able to penetrate cells within the eye due to peptides. Other aspects are generally directed to methods of making or using such particles, kits involving such particles, or the like.
US11559578B2	Biodegradable cationic polycarbonates as adjuvants for vaccines A method for formation of a vaccine comprising combining a cationic polymer adjuvant with an antigen to form first immunoparticles through charge interactions and producing a treatment formulation for the vaccine comprising the first immunoparticles.
US11559577B2	Immunogenic composition forming a vaccine, and a method for its manufacture An immunogenic composition forming a vaccine includes a nanoparticle delivery system comprising at least a nanoparticle, wherein the at least a nanoparticle comprises a lipid layer exterior including a plurality of lipids, cholesterol, and a primary alkyl amine including a positively charged amino group head and at least a carbon tail and an antigen incorporated in the at least a nanoparticle, wherein the antigen comprises a nucleic acid encoding a protein from a coronavirus.
US11559576B2	Anti-human papillomavirus (HPV) antigen-binding proteins and methods of use thereof The present invention provides antigen-binding proteins that specifically bind to an HLA-displayed human papillomavirus (HPV) peptide, and therapeutic and diagnostic methods of using those binding proteins.
US11559571B2	Nucleotide sequence expressing an exosome-anchoring protein for use as vaccine The present invention concerns a nucleotide sequence expressing a fusion protein, said fusion protein comprising or consisting of an exosome-anchoring protein fused at its C-terminus with an antigen, or a DNA expression vector comprising said nucleotide sequence, for use as vaccine.
US11559568B2	Short chain ceramide-based lipids and uses thereof Provided herein, in some aspects, are delivery vehicles comprising a glycosphingolipid and an agent to be delivered attached to the glycosphingolipid. In some embodiments, the glycosphingolipid comprises an oligosaccharide and a short chain (e.g., C0-C3) ceramide. In some embodiments, the agent to be delivered is a therapeutic agent. The glycosphingolipid is able to deliver the agent to a cell or to a cellular compartment, as well as across the musical barrier. In some embodiments, agents delivered using the glycosphingolipid described herein exhibit longer half-life, compared to agents delivered alone. Methods of delivering a therapeutic agent to a subject for treating a disease using the glycosphingolipid delivery vehicle are also provided.
US11559567B2	Dosage regimen for pegylated interferon A pegylated type I interferon for use in treating an infectious disease, cancer, or myeloproliferative disease in a subject in need thereof, wherein a 50 to 540 μg dose of the pegylated type I interferon is administered to the subject at a regular interval for a treatment period, the interval being 3 to 8 weeks.
US11559561B2	Composition and methods for treatment of primary ciliary dyskinesia The present invention provides, among other things, methods and compositions for treating primary ciliary dyskinesia (PCD) based on mRNA therapy. The compositions used in treatment of PCD comprise an mRNA comprising a dynein axonemal heavy chain 5 (DNAH5) coding sequence and are administered at an effective dose and an administration interval such that at least one symptom or feature of PCD is reduced in intensity, severity, or frequency or has a delayed onset. mRNAs with optimized DNAH5 coding sequences are provided that can be administered without the need for modifying the nucleotides of the mRNA to achieve sustained in vivo function.
US11559558B2	Weekly dosing regimens for anti-CD30 vc-PAB-MMAE antibody drug-conjugates Methods for the treatment of CD30-expressing cancers are provided. The methods comprise administering to a subject in need thereof a weekly dose of from about 0.8 mg/kg to about 1.8 mg/kg of an antibody-drug conjugate compound having formula (I); or a pharmaceutically acceptable salt thereof; wherein: mAb is an anti-CD30 antibody unit, S is a sulfur atom of the antibody, A- is a Stretcher unit, and p is from about 3 to about 5.
US11559555B2	Crude drug composition for preventing or treating respiratory diseases The present disclosure relates to a pharmaceutical composition for preventing or treating respiratory diseases and a food composition for preventing or relieving respiratory diseases comprising as an active ingredient two or more mixed extracts selected from the group consisting of a Brassicae Semen extract, an Adenophorae Radix extract, a Lonicerae Folium extract and a Perillae Semen extract. A composition comprising mixed extracts of Brassicae Semen, Adenophorae Radix, Lonicerae Folium and Perillae Semen of the present disclosure has an advantage of preventing respiratory diseases and relieving the symptoms of respiratory diseases, restores damages in the lung tissue, inhibits aging action and inflammation induced by inflammation-inducing substances such as fine dust, and has an excellent antioxidant effect. More particularly, the composition of the present disclosure increases the expression of a telomerase which extends the length of a telomere.
US11559553B2	Products derived from amniotic fluid and methods of use Uncultured amniotic cell and protein fraction products derived from amniotic fluid and methods of preparing and using those compositions are provided. According to the methods of the present invention, uncultured amniotic cell and protein products may be derived from a large sample of amniotic fluid to provide a higher concentration of tissue regeneration components. Described are methods for separating uncultured amniotic cells or protein fractions from other components of amniotic fluid and the resulting uncultured amniotic cell and protein products. Furthermore, the present invention includes methods for delivering the uncultured amniotic cell and protein products to the skin and eye, including before, during, or after a treatment procedure.
US11559549B2	PD1-specific chimeric antigen receptor as an immunotherapy Provided herein are methods and compositions useful for treating PDL1 and/or PDL2 positive cancers through adoptive cell transfer of T cells genetically engineered to express a PD1-specific chimeric antigen receptor. Co-stimulatory domains such as Dap 10 may be included to enhance efficacy.
US11559548B2	Method for producing helper T cells from pluripotent stem cells A method of producing helper T cells, comprising: (i) culturing T cells, which have been induced from pluripotent stem cells and into which a CD4 gene or a gene product thereof has been introduced, in a medium containing IL-2 and IL-15; and (ii) isolating CD40L-highly expressing T cells from cells obtained in step (i).
US11559546B2	Antibacterial composition and its use in treating bacterial infections An antibacterial composition that comprises as active compound at least one light isotope of an element selected from the group which consists of 1H, 12C, 16O, 14N, 39K, 24Mg, 64Zn, 85Rb, 28Si, 54Fe, 92Mo, 74Se, 58Ni, 70Ge, 52Cr, 63Cu, 50V, or combinations thereof, wherein the composition is enriched for the at least one light isotope. A method of treating and preventing bacterial diseases in humans and non-human animals by administering the composition. The use of the said composition in human and veterinary medicine for the prevention and treatment of diseases in humans and non-human animals and also as an antiseptic and disinfectant.
US11559545B2	Inhibition of UCHL1 in high-grade serous ovarian cancer In certain aspects, the present disclosure provides methods and materials for the treatment of cancer. In accordance with some forms, the disclosure provides methods for the treatment of cancer which include inhibition of ubiquitin carboxyl-terminal hydrolase.
US11559543B2	Immunostimulator, pharmaceutical composition, and food or beverage Provided is an immunostimulator containing: chitosan and/or a chitosan derivative each having a weight-average molecular weight of 10k to 1000k; and an anionic surfactant, the immunostimulator being in particulate form. Also provided are a pharmaceutical composition and an alimentary product, each containing the immunostimulator as an active ingredient.
US11559541B2	Topical capecitabine for the treatment of hyperproliferative skin conditions The present invention relates to a novel and unexpected method of using topical Capecitabine composition to obtain therapeutically effective amounts of fluorouracil (FU) within the skin of a subject afflicted with hyperproliferative or inflammatory skin condition. The method comprising topically administering a pharmaceutical composition comprising Capecitabine or a hydrate or solvate thereof to the affected area of the skin of the subject, to form therapeutically effective amounts of FU within the skin.
US11559537B2	Combination therapies using caspase-1 dependent anticancer agents and PGE2 antagonists Disclosed are combination therapies including administration of Caspase-1 dependent anticancer agents and PGE2 antagonists, and the use of such therapies in the treatment of cell proliferative diseases.
US11559536B2	Compositions and methods for the treatment of inflammation in urological pathology The present disclosure provides compositions and methods for the treatment of inflammation in urological pathologies.
US11559531B2	Liquid formulation compositions, medicament delivery devices, and methods of preparation and use thereof The invention provides liquid formulation compositions and medicament delivery devices, and methods for preparing and using the same. For example, the liquid formulation composition is an emulsion including a solvent and liquid particles, which includes surfactants and are dispersed in the solvent. The volume average particle size of the liquid particles is less than about 100 μm; the surface tension of the liquid formulation composition is less than about 60 mN/m; and the absolute value of zeta potential is greater than about 15 mV. The containment vessel may be a sprayer or a dropping device. The invention also provides methods for preparation of the liquid formulation compositions and medicament delivery devices as well as methods for using the same in treatment of various diseases and condition, for example, otitis media, otitis externa, rhinitis, sinusitis, lower respiratory tract inflammation, xerostomia (dry mouth), xerophthalmia (dry eyes) and xeromycteria (dry nose).
US11559530B2	Oral testosterone undecanoate therapy The present disclosure provides methods and compositions for testosterone replacement therapy. The methods and compositions employ a fixed dose dosing regimen that does not require titration or dose adjustments and that can provide a therapeutically effective amount of a testosterone ester while avoiding unacceptably high testosterone levels.
US11559524B2	Composition for reducing nervous system injury and method of making and use thereof This application discloses a composition comprising an amiloride and/or an amiloride analog which can be used for reducing nerve injury or nervous system injury in a subject. The formulation of such composition is also disclosed. The application further directs to methods for treating nerve injury or nervous system injury by administering to the subject a therapeutically effective amount of a pharmaceutical composition comprising amiloride, an amiloride analog or a pharmaceutically acceptable salt thereof.
US11559517B2	Promotion of epithelial repair There is provided a method for promoting epithelium repair in a subject, the method comprising administering to the subject a therapeutically effective amount of an activator of PI3K/Akt signalling.
US11559516B2	Pharmaceutical combinations for treating cancer The present invention is directed to a combination comprising a proteasome inhibitor and a compound of formula I or a pharmaceutically acceptable salt thereof: to a pharmaceutical composition and to a kit both comprising said combination, to the combination, composition or kit for use in the treatment of cancer, and to a method of treatment of cancer in a patient in need thereof comprising administering to said patient an effective amount of said combination, composition or kit.
US11559514B2	Compositions and methods of use of antibacterial drug combinations The present disclosure encompasses antibacterial compositions and methods of treating bacterial infections caused by resistant bacteria.
US11559510B2	Isoflavonoid composition with improved pharmacokinetics A method for providing a steady state plasma concentration of about 20-400 ng/ml of isoflavonoid compounds comprising the steps of a first rectal administration of the compound in a lipophilic suppository base followed by further rectal administrations no earlier than 4, 8 or 16 hours after the previous rectal administration.
US11559506B2	Pharmaceutical composition A pharmaceutical composition is described. The composition comprises: (i) at least one formoterol compound selected from formoterol, pharmaceutically acceptable salts of formoterol, prodrugs of formoterol, solvates of formoterol, solvates of pharmaceutically acceptable salts of formoterol and solvates of prodrugs of formoterol; (ii) at least one corticosteroid; (iii) a surfactant component comprising at least one surfactant compound; and (iv) a propellant component comprising 1,1-difluoroethane (R-152a).
US11559504B2	Ceramide nanoliposomes, compositions and methods of using for immunotherapy Methods and compositions for treating cancer are provided. Compositions comprising ceramide nanoliposomes are administered to a subject in need of such treatment. The composition administration also enhances immunotherapy. Further administering compositions in combination with tumor antigen specific T-cells, and/or compositions in combination with tumor antigen expressing cells, and/or said compositions in combination with antagonists of PD-1 provides for enhanced results. Administration of the compositions provides for effective treatment of tumors including regression and eradication of established tumors.
US11559498B2	Compositions and methods for in vivo lung and blood SNO repletion A method of treating coronavirus infection, post-acute sequelae of coronavirus infection, and viral mediated respiratory distress in a subject in need thereof includes administering to the subject a therapeutically effective amount of agent that promotes, increases, and/or induces hemoglobin nitrosylation within red blood cells (RBCs) and GSNO levels in the lung or airways of the subject.
US11559497B2	Transdermal drug delivery system for ketamine Provided herein are transdermal delivery devices comprising ketamine, such as monolithic transdermal patches. Also provided herein are methods of preparing transdermal delivery devices. The transdermal delivery device and monolithic patch herein can have various uses, for example, for treating various diseases or disorders, such as depression, anxiety, and/or pain in a subject in need thereof.
US11559496B2	Tissue thickness compensator configured to redistribute compressive forces A tissue thickness compensator may generally comprise a compressible core comprising a plurality of movable particles, and a wrap surrounding the compressible core. The plurality of movable particles may comprise at least one medicament. A tissue thickness compensator may generally comprise a compressible core comprising a plurality of crushable particles, and a wrap surrounding the compressible core. The plurality of crushable particles may comprise at least one medicament. The compressible core may comprise a material selected from a group consisting of a biocompatible material. The wrap may comprise a material selected from a group consisting of a biocompatible material. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.
US11559490B2	Pharmaceutical formulation A pharmaceutical formulation has (S)-[2-chloro-4-fluoro-5-(7-morpholin-4-yl-quinazolin-4-yl)phenyl]-(6-methoxy-pyridazin-3-yl)methanol or pharmaceutically acceptable salt thereof.
US11559488B2	Pharmaceutical compositions having high drug loadings of medium chain triglycerides and methods related thereto This invention relates to high drug load compositions of medium chain triglycerides (MCT), and to methods for treatment with such compositions at amounts effective to elevate ketone body concentrations so as to treat conditions associated with reduced neuronal metabolism, for example Alzheimer's disease.
US11559486B2	Ready-to-use formulation for Vincristine Sulfate Liposome Injection Disclosed herein are various compositions comprising neoplastic formulations and their methods of use.
US11559485B2	Orally disintegrating tablet comprising amorphous solid dispersion of nilotinib Amorphous solid dispersions and pharmaceutical compositions of the protein kinase inhibitor nilotinib. The pharmaceutical compositions may be used in methods of treating a proliferative disorder such as cancer. In particular, the present disclosure provides a pharmaceutical composition in the form of an orally disintegrating tablet. In some embodiments, the pharmaceutical compositions can be administered without regard to food consumption. In other embodiments, the pharmaceutical compositions can be administered at a significantly lower dose as compared to a commercially available immediate-release nilotinib formulation, while providing a comparable therapeutic effect.
US11559484B2	Film formulations containing dexmedetomidine and methods of producing them Disclosed herein is a self-supporting, dissolvable, film containing dexmedetomidine or a pharmaceutically acceptable salt thereof. The film is administered orally to treat various conditions, particularly agitation, by transmucosal delivery of the active agent.
US11559470B2	Feeding tube with electromagnetic sensor There is provided feeding tubes including an electromagnetic sensor including a sensor body comprising a core positioned at a distal end of the sensor lumen, and a wire extending along the length of the feeding tube, wherein an RF induced heating of the feeding tube in an MRI environment is below 5 degrees.
US11559468B2	Syringe pump for automatic drug compounders Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes controllable fluid pathways. The cartridge may include a syringe pump for moving fluid and/or gas, and one or more syringe valves or rotary valves for controlling which of the controllable fluid pathways is open for flow of the fluid and/or gas.
US11559466B2	Covering assembly with coagulant compartment and uses thereof in a blood monitoring/management system Disclosed is a covering/lid assembly having a first compartment, a second compartment, or both. Each compartment will comprise a top side and a bottom side, the bottom side of the compartment comprising a frangible material. The first or second compartment may comprise a first material or a second material. The first or second material may comprise a flocculated red blood cell coagulant, or a red blood cell flocculent. The material within a compartment may be selectively released upon compressing a dimple and/or button located directly above the first and/or second compartment. A collection and/or biological waste management and disposal system is presented, comprising a lid/covering assembly as described and a collection container. The lid may include a perimeter having a threaded and/or snap-on assembly suitable for securely attaching the lid to a collection canister. The collection canister may comprise a red blood cell flocculent coating.
US11559462B2	Percussive massage device and method of use A percussive massage device that includes a housing, an electrical source, a motor positioned in the housing, a switch for activating the motor, and a push rod assembly operatively connected to the motor and configured to reciprocate in response to activation of the motor. The housing includes first, second and third handle portions that cooperate to define a handle opening, wherein the first handle portion defines a first axis, the second handle portion defines a second axis and the third handle portion defines a third axis, and wherein the first, second and third axes cooperate to form a triangle.
US11559459B2	Rollator A rollator includes a collapsible frame supported on a plurality of wheels, a seat supported on the frame, a pair of handlebars, and a braking mechanism.
US11559456B2	Craniosacral cradle system and method A formed therapeutic tool has a base in a generally heart-shaped configuration with a narrow arcuate front, a wide rear, tapering sides, and a concave bottom. A rearward support is formed of two similarly configured projections. The projections are laterally spaced. Each projection has a linear high point and a semicircular surface. The tool has a forward support formed of two similarly configured inclines. Each incline has an arcuate high point adjacent to one of the projections and an arcuate low point adjacent to the front. A ovoid shaped central recess extends downwardly between the inclines and the projections. The central recess terminates in an ovoid shaped floor with a lower surface constituting a portion of the concave bottom of the base. The tool having a Durometer of from 36 to 45 on a Shore A scale and an Indentation Force Deflection of from 8 to 9.
US11559454B2	Rotational support apparatus Moving an individual with limited mobility from one seated position to another requires a significant effort from the caregiver and can expose the individual and the caregiver to several injuries. The rotational support apparatus is useful in safely assisting individuals with limited mobility to move from one seated position to another with minimal effort. The apparatus is lightweight and portable. The base of the apparatus rotates so the caregiver can easily move the position of the individual. The base can be coupled with a stabilizing device that the individual with limited mobility can hold on to while the caregiver rotates them to another position.
US11559451B2	Fluid source for supplying fluid to therapy devices A fluid source comprises a connector assembly for connecting a fluid supply device to either a first therapy device or to a second therapy device. A controller automatically provides a first configuration of a user interface associated with a first therapy when a supply connector is operatively coupled to the first therapy device and provides a second configuration of the user interface associated with a second therapy, different than the first configuration, when the supply connector is operatively coupled to the second therapy device. A hanger assembly is provided to hang the fluid source on different support structures. The fluid source also comprises a housing with a watershed region to shed liquid away from the user interface.
US11559450B2	Patient support apparatus user interfaces A patient support apparatus comprising a patient support deck operatively attached to a base with a lift mechanism interposed between the base and the patient support deck to move the patient support deck between first and second vertical configurations relative to the base. A user interface configured to operate the patient support apparatus is provided and comprises a screen configured to display visual content in first and second content layouts. The screen is coupled to the patient support deck for concurrent movement between the vertical configurations A controller disposed in communication with the screen and the lift mechanism is configured to display the visual content in the first content layout when the patient support deck is in the first vertical configuration, and further configured to display the visual content in the second interface layout when the patient support deck is in the second vertical configuration.
US11559449B2	Patient transport apparatus with movable head section A patient transport apparatus comprises support structure. The support structure comprises a base, a support frame, and a patient support deck. A headboard and a footboard are coupled to the support structure. The support frame comprises a head section and a body section, the body section coupled to the patient support deck. The patient support deck comprises a patient support surface capable of articulating relative to the support frame. The head section is movable relative to the body section to define first and second configurations of the support frame, the support frame having a first footprint in the first configuration and a second footprint, smaller than the first footprint, in the second configuration.
US11559448B2	Medical support apparatus A medical chair includes a base, a seat section, and a leg rest pivotally mounted relative to the seat and adapted to move between an extended position and a retracted position. The chair further includes a scissor mechanism coupled to the leg rest to extend and contract the leg rest and an actuator mounted on one end relative to the seat section and having an extendible driving end coupled to the leg rest wherein when the extendible driving end extends the extendible driving end pivots the leg rest about the pivot axis and extends the scissor mechanism.
US11559446B2	Anti-rollback braking system for wheelchairs A wheelchair comprising a seat back, a seat bottom, a frame, two front wheel assemblies, two drive wheels, two wheelchair wheels, and an anti-rollback wheelchair braking system consisting of two braking units, each unit comprising a housing cylinder body cap, a housing cylinder body, a housing cylinder mounting assembly, a wheelchair mounting assembly, rotatable toggle clamp direction selection lever, an anti-rollback, one-way, brake assembly, and a toggle clamp assembly for engaging the said anti-rollback, one-way, brake assembly with a wheelchair wheel. A parking brake assembly may also be included. The invention may be manufactured and sold as a whole wheelchair assembly or a retrofit kit for standard wheelchairs.
US11559431B2	Devices and methods useable for treatment of glaucoma and other surgical procedures A device and method for cutting or ablating tissue in a human or veterinary patient includes an elongate probe having a distal end, a tissue cutting or ablating apparatus located adjacent within the distal end, and a tissue protector extending from the distal end. The protector generally has a first side and a second side and the tissue cutting or ablating apparatus is located adjacent to the first side thereof. The distal end is structured to be advanceable into tissue or otherwise placed and positioned within the patient's body such that tissue adjacent to the first side of the protector is cut away or ablated by the tissue cutting or ablation apparatus while tissue that is adjacent to the second side of the protector is not substantially damaged by the tissue cutting or ablating apparatus.
US11559424B2	Adhesive ostomy wafer including a stoma-receiving hole and a neutralizer contained in an envelope, with the envelope extending to an edge of the stoma-receiving hole An adhesive ostomy wafer includes a first adhesive, a skin-facing adhesive located proximal of the first adhesive, and a neutralizer located in an envelope that is contained by the first adhesive and the skin-facing adhesive. The adhesive ostomy wafer includes a stoma-receiving hole formed through wafer such that the first adhesive, the neutralizer, and the skin-facing adhesive are exposed within the stoma-receiving hole.
US11559422B2	Urine collection system for use on patient support apparatus A urine collection system is provided for use on a patient support apparatus. The urine collection system comprises a housing and a container for mounting to the housing in a releasable manner.
US11559417B1	Delivery systems and methods of endoluminal delivery of branched vascular endoprosthetic devices A catheter assembly for delivery of an expandable implant having at least one branch portal, which utilizes a secondary sleeve for releasably constraining a middle portion of the expandable implant after releasing a primary constraining sleeve used for constraining the expandable implant toward a delivery configuration for endoluminal delivery; and methods of using the same.
US11559415B2	Radially self-expanding stents Described herein are radially self-expanding stents. The disclosed stents can be used to widen arteries and/or veins of a patient to counteract or combat narrowing of the arteries and/or veins associated with certain congenital diseases, such as aortic coarctation. As an example, the disclosed stents are configured to be placed at or near a narrowed portion of the aorta where the stent produces a radial outward force on the aorta. The radial force produced by the stent widens the aorta and causes the stent to expand with the aorta. The disclosed stents can be crimped to relatively small sizes for placement in small patients (e.g., less than about 10 kg in size) and can be configured to expand to widen the aorta and to accommodate growth in the patient.
US11559414B2	Stent A stent which has a cylindrical tubular shape in which wires cross each other and are woven includes first regions each including a horizontal folding crossing portion in which the wires are folded in an axial direction and cross each other and a vertical folding crossing portion in which the wires are folded in a circumferential direction and cross each other. The first region is a region in which the horizontal folding crossing portion and the vertical folding crossing portion are arranged in the circumferential direction, and the first regions are arranged at intervals in the axial direction.
US11559410B2	Artificial spinal disc and artificial disc insertion method using the same Provided is an artificial spinal disc including an upper disc formed in a plate shape with top coupled to an upper vertebra, a protruding joint portion protruding from a lower surface of the upper disc, and a lower disc formed in a plate shape with bottom coupled to a lower vertebra wherein the protruding joint portion is seated on an upper surface of the lower disc. According to the foregoing description, the artificial disc is implanted through the lateral or anterolateral approach to the spine, rather than the anterior approach, and such lateral implantation is straightforward.
US11559408B2	Methods and apparatus for accessing and treating the facet joint Methods and systems are disclosed for accessing and treating the interior of the facet joint for vertebral distraction and immobilization. The systems include a number of tools that facilitate access to the facet joint, distraction of the articulating decortication of the articulating surfaces, and delivery of implants and agents into the facet joint for fusion.
US11559400B2	Tricuspid valve repair using tension A method of reducing tricuspid valve regurgitation is provided, including implanting first, second, and third tissue anchors at respective different first, second, and third implantation sites in cardiac tissue in the vicinity of the tricuspid valve of the patient. The geometry of the tricuspid valve is altered by drawing the leaflets of the tricuspid valve toward one another by applying tension between the first, the second, and the third tissue anchors by rotating a spool that (a) winds therewithin respective portions of first, second, and third longitudinal members coupled to the first, the second, and the third tissue anchors, respectively, and (b) is suspended along the first, the second, and the third longitudinal members hovering over the tricuspid valve away from the annulus of the tricuspid valve. Other embodiments are also described.
US11559395B2	Transcatheter prosthetic heart valve and delivery system A prosthetic mitral valve has an interior stent and an exterior mesh surrounding the interior stent. The prosthetic mitral valve is released from a capsule and self-expands within a native mitral valve. The exterior wire mesh has a first portion with an enlarged diameter sized for placement above a mitral annulus and a second portion with a reduced diameter for contacting the mitral annulus. Capturing elements are provided on the interior stent. The capturing elements extend in a ventricular direction beyond the exterior wire mesh and then turn in an atrial direction for trapping native mitral leaflets against an outer surface of the wire mesh. A plurality of valve leaflets is provided within the interior stent for replacing the function of the native mitral valve.
US11559393B2	Multi-part intraocular lens with locking mechanism A multi-part intraocular lens (IOL) with an interchangeable optic seated on a base and secured by a locking mechanism. The optic comprises an anterior surface with a diameter greater than a diameter of a ring of the base. The posterior side of the optic has a posterior surface, a transition region for contact with the base, and sidewalls and tabs radially outward of the transition region. The sidewalls and tabs overlap at least a portion of the ring to reduce or even prevent decentration and tilt of the optic. Each tab has a lateral extension for coupling to the base.
US11559392B2	Intraocular lens The invention is directed to an intraocular lens having an optical body, two haptic elements and first and second sets of a plurality of ropes corresponding to respective ones of the first and second haptic elements. The ropes are secured to the optical body and to the haptic element and have a severing sequence. The haptic elements each have a compressed state, a partly compressed state and an uncompressed state. In the compressed state, the first rope of the severing sequence is configured to deform the haptic element in a direction toward the optical body as a result of which the first rope is under a tensile stress and the rest of the ropes are stress-free and, by the ropes being severed successively in the severing sequence, the haptic element can be brought firstly to the partly compressed state. All the ropes are severed in the uncompressed state.
US11559388B1	Constructs and methods for repairing a tendon with a reduced risk of reinjury A tendon repair suture tape comprising a flat braid of elastic, absorbable fibers and high strength fibers, the tape being at least 1 mm wide and 2 cm long, and less than 0.2 mm high. The suture tape includes at least 4 absorbable fibers and at least 4 high strength fibers. Further, the suture tape is capable of being stretched at least 10% from its shortest length to the length at which it breaks, presents an increasing resistance to further stretching as it is stretched, and is capable of withstanding a load of at least 260 Newtons before breaking.
US11559386B2	Endovascular graft systems and methods for deployment in main and branch arteries Endovascular systems for deployment at branched arteries include a main tubular graft body deployable within a main artery including a proximal end and an opposed distal end. The proximal and distal ends have a tubular graft wall therein between. A plurality of inflatable channels are disposed along the main tubular graft body, and at least one stent segment is disposed along the tubular graft wall of the main tubular graft body. The plurality of inflatable channels are configured to be inflatable with an inflation medium. The at least one stent segment is disposed between two or more adjacent inflatable channels of the plurality of inflatable channels.
US11559384B2	Stent with selectively curved region A stent with a selectively curved region. The stent includes a radially expandable tubular framework and a covering surrounding the tubular framework. A stent also includes a drawstring having a first end attached to the tubular framework at a first attachment location proximate the distal end of the tubular framework. The second end of the first drawstring is manipulatable proximate the proximal end of the tubular framework to deflect the tubular framework into a curved configuration.
US11559373B2	Stable winged affixation system for guided dental implantation A stable affixation system for dental implantation includes a fixation tray having, for rapid placement, a housing defining a chamber whose inner surface is configured to house a flowable or malleable material and be placed over one or more teeth during guided dental implantation surgery. A central portion not configured to flex is situated between housing side walls. Each such side wall has an upper side portion and a lower side portion. Without the lock a squeezing force on the upper side portions flexes the lower side portions outward. The lock urges the upper side portions outward so as to flex the lower side portions inward. The lock reduces or eliminates freedom of movement of the tray. The system allows rapid removal and is sturdy enough to withstand forces including from various angles and leverage. The central portion may hold registration elements.
US11559372B2	Patient-mounted surgical retractor Surgical tissue retraction systems and methods are described herein. Such systems and methods can be employed in some embodiments to provide medial-lateral tissue retraction to increase access to a surgical site. In one embodiment, a surgical instrument can include a body configured to couple to an implantable anchor, a first tissue manipulating implement coupled to the body and capable of polyaxial movement relative thereto, and a second tissue manipulating implement coupled to the body and capable of polyaxial movement relative thereto. Further, the first and second tissue manipulating implements can be opposed to one another such that they can move any of toward and away from one another.
US11559371B2	Neurosurgical apparatus Neurosurgical apparatus has a guidance device having a guide tube and a neurosurgical instrument for insertion into the guide tube. The inner surface of the guide tube is arranged, for example profiled, to at least partially engage the outer surface of the neurosurgical instrument when inserted therein. The guide tube thus guides the neurosurgical instrument along a predefined path through the guide tube. At least one of the guidance device and the outer surface of the neurosurgical instrument are configured to provide a fluid return path for carrying any fluid displaced from within the guide tube during insertion of the neurosurgical instrument into the guide tube. A seal may also be provided for sealing the fluid return path.
US11559370B2	Endoscopic treatment tool An endoscopic treatment tool, includes an elongated member having a distal end and a proximal end; a braid disposed between the distal end and the proximal end of the elongated member; a distal indicator disposed on the elongated member between a distal end and a proximal end of the braid, the distal indicator extending along a longitudinal axis of the elongated member; a proximal indicator disposed between the distal end and the proximal end of the braid on the elongated member at a more proximal side of the elongated member than the distal indicator, the proximal indicator extending along the longitudinal axis; and a pre-curved shape portion formed in a curved shape, wherein each of the distal indicator and the proximal indicator has a width less than half of an outer circumferential surface of the elongated member in a circumferential direction of the elongated member, respectively.
US11559369B2	Sharps container A container for disposal of medical waste is provided that comprises a receptacle with an open top. A lid is attached to the receptacle to cover the open top of the receptacle. The lid has an elongated opening sized to permit the introduction of medical waste into the receptacle. A closure flap is connected to the lid to selectively close the lid opening. The closure flap is movable between an open position, a closed position and a locked position. The closure flap is attached to the lid by axial hubs that extend from each side of the closure flap through openings in the side walls of the lid. Covers attached to the outside of the side wall of the lid and engaged with the closure flap axial hub. The container may also include a locking external cabinet that encloses the receptacle and can be mounted to a wall.
US11559365B2	Systems and methods for entering and exiting a teleoperational state A teleoperational medical system includes a teleoperational control system, a teleoperational manipulator, an operator controller. The control system includes a processing unit configured to: determine a position and orientation of a marker on an operator of the operator controller; determine whether a head portion of the operator is directed toward or away from a display region of a display; based on a determination that the head portion is directed toward the display region, initiate an operator following mode in which a movement of the operator controller provides a corresponding movement to the teleoperational manipulator; and based on a determination that the head portion is directed away, suspend the operator following mode. The determination that the head portion is directed away from the display region of the display device includes determining whether the head portion of the operator is directed away from the display region for a threshold time period.
US11559364B2	Detection of user touch on controller handle Implementations relate to detecting user touch on a controller handle. In some implementations, a non-controlling mode of a control system is activated, and in the non-controlling mode, one or more actuators are controlled to cause a vibration to be provided on a handle of a controller. The vibration is sensed with one or more sensors, and a difference in the vibration is determined to have occurred relative to a reference vibration using the one or more sensors, where the difference satisfies one or more predetermined thresholds. A controlling mode of the system is activated in response to determining the difference in the vibration, and the vibration is modified on the handle in response to detecting the change in the vibration.
US11559358B2	Surgical assembly with kinematic connector A surgical assembly for kinematically coupling two surgical components is provided. The surgical assembly includes a first surgical component having a receiver, which defines a cavity and has a plurality of constraint surfaces accessible in the cavity. The surgical assembly further includes second surgical component having a key, which has a triplicity of kinematic elements to repeatably position the key in the receiver. The surgical assembly further includes a preloading mechanism having a load member arranged to secure the key in the receiver such that the kinematic elements contact the receiver at the plurality of constraint surfaces such that the key is kinematically constrained to the receiver by being constrained by six points of contact with the receiver.
US11559357B2	Systems and methods for navigating to a target location during a medical procedure The systems and methods of the present disclosure are used for guiding a medical instrument towards a target, the method positioning a medical instrument at a first location within a patient anatomy, wherein the medical instrument comprises at least one sensor, determining a first biomarker measurement using the at least one sensor, determining a second biomarker measurement using the at least one sensor, comparing the first biomarker measurement with the second biomarker measurement to determine a proximity to the target to provide a first comparison, and providing guidance for moving the medical instrument based on results of the first comparison.
US11559355B2	Augmented and virtual reality for use with neuromodulation therapy A virtual or augmented reality system is disclosed which is capable of both (i) evaluating prospective implantable neurostimulator patient candidates, and (ii) determining optimal stimulation settings for already-implanted neurostimulation patients. Physiological sensors are included with the system to provide objective measurements relevant to a patient's symptoms, such as pain in a Spinal Cord Stimulation (SCS) system. Such objective measurements are determined during the presentation of various virtual or augmented environments, and can be useful to determining which patients are suitable candidates to consider for implantation. Stimulation settings for already-implanted patients may be adjusted while presenting a virtual or augmented environment to the patient, with objective measurements being determined for each stimulation setting. Such objective measurements can then be used to determine optimal stimulation settings for the patient.
US11559352B2	Systems and methods for lesion assessment Ablation visualization and monitoring systems and methods are provided. In some embodiments, such methods comprise applying ablation energy to a tissue to form a lesion in the tissue, illuminating the tissue with a light to excite NADH in the tissue, wherein the tissue is illuminated in a radial direction, an axial direction, or both, monitoring a level of NADH fluorescence in the illuminated tissue to determine when the level of NADH fluorescence decreases from a base level in the beginning of the ablating to a predetermined lower level, and stopping ablation of the tissue when the level of NADH fluorescence reaches the predetermined lower level.
US11559348B2	Power modulated endometrial lining tissue ablation A system is configured to delivering radiofrequency power to the endometrial lining tissue of a uterine cavity, including modulating the delivered power so that a measured impedance of the endometrial lining tissue tracks a target impedance as a function of time, wherein the target tissue impedance is derived from a function that approximates a preferred endometrial lining tissue ablation impedance curve that is determined based upon a measured impedance of the endometrial lining tissue after RF power has been delivered for a predetermined initial time period.
US11559346B2	Electrosurgical network An electrosurgical system comprising: a plurality of electrosurgical connection units, each electrosurgical connection unit comprising an input port connectable to an electrosurgical channel and an output port connectable to an electrosurgical instrument, the electrosurgical connection unit configured to connect the input port to the output port; an electrosurgical network comprising a plurality of electrosurgical links that connect the input ports of the electrosurgical connection units to an electrosurgical channel; and a control unit configured to: receive information from a device indicating that the device has detected an electrosurgical generator connected to the electrosurgical channel, the device being one of the electrosurgical connection units and an electrosurgical output device connected to the electrosurgical channel; determine a location of the electrosurgical generator in the electrosurgical network based on the received information; and transmit one or more control signals to the electrosurgical connection units and/or one or more electrosurgical output devices connected to the electrosurgical channel to cause the output port of a selected combination of electrosurgical connection units to be connected to the electrosurgical channel based on the determined location of the electrosurgical generator.
US11559343B2	Photodynamic articular joint implants and methods of use Photodynamic devices for replacement of an articular head of a bone are provided. In an embodiment, a photodynamic device includes a photodynamic support member and an articular member attachable, either fixedly or removably, to the photodynamic support member and having a bearing surface. In an embodiment, the articular member includes a recess designed to receive the photodynamic support member. In an embodiment, the photodynamic support member includes an opening into which a shaft of the articular member can be inserted to attach the articular member to the photodynamic support member.
US11559337B2	Expended tab reinforcement sleeve A sleeve can be adapted to reinforce a bone anchor, and can include a body, a lock, and an actuator. The body can include a first sleeve arm and a second sleeve arm, where each can extend longitudinally along opposing sides of a longitudinal bore open at a distal end of the sleeve. The lock can be coupled to the body and releasably securable to a channel of a head of the bone anchor to secure the sleeve to the anchor.
US11559333B2	Bone anchor An anchor assembly can be couplable to a bone and can include an anchor and a housing. The anchor can include a shank securable to bone and a head coupled to a proximal portion of the shank.
US11559332B2	System for connecting a connection device to a bone System for connecting a connection device to a bone with a bone pin, wherein the system comprises a connection device provided with an opening for receiving the bone pin, and wherein the system further comprises a locking device arranged to be received in the opening of the connection device and which is arranged to engage the bone pin for locking the bone pin with respect to the connection device, wherein the locking device is movable between a locked position, wherein the bone pin is locked with respect to the connection device, and an unlocked position wherein the bone pin is movable with respect the connection device, wherein the system further comprises a blocking mechanism for at least partially blocking the opening in the connection device upon removal of the bone pin from the opening.
US11559330B2	Surgical cannula with removable pressure seal The present disclosure relates to a surgical cannula with a removable seal at one end. The surgical cannula is a wide gauge surgical cannula, that allows materials and tools to be introduced into a body during a surgical procedure. The cannula includes a seal structure at one end, which may be attached to and detached from the cannula body as desired. The seal structure includes one or more valves that retain pressure within the cannula. The one or more valves are configured to allow a tool through the valve(s), while retaining pressure inside the cannula, so that surgical tools may be inserted through the cannula even when the seal structure is attached to an end of the cannula.
US11559327B2	Optical obturator An optical obturator apparatus includes an obturator sleeve defining a longitudinal axis and having a longitudinal bore for receiving surgical instrumentation and a transparent window mounted to the obturator sleeve and being dimensioned and configured to pass through tissue. The transparent window is mounted for movement between a first position in general alignment with the longitudinal axis of the obturator sleeve and a second position radially displaced from the longitudinal axis to thereby expose the longitudinal bore of the obturator sleeve to permit passage of the surgical instrumentation. The transparent window may include a cutting blade, or alternatively two cutting blades, adapted to penetrate tissue.
US11559326B2	Disposable circumcision apparatus and method of use of this apparatus New disposable system devises and procedure for circumcision. The new procedure is by using the clamp in the same way of using bone cutter forceps, the penis marked by skin marker below the level of coronal sulcus, the prepuce retracted, a glans protector probe introduced above the glans, the prepuce pulled back over the probe, grasped by fingers on the probe to have painless holding. The modified bone cutter with blind cut end and groove on the upper surface is applied on the level of the skin mark. Light pressure separates the glans protector from its handle, then strong pressure on prepuce applies by this modified bone cutter, a sharp knife cuts the prepuce above the instrument, left a skin tag in the groove of the instrument, a heated oval shape stainless steel coated cupper cautery pass above the grove, the heating is by gas or electricity, but the electrical current must be cut off before application, the temperature between 140-300, glans protector removed no need for any dressing. Another modification is the removable disposable heads of the bone cutter. The result is very rapid circumcision with the lowest complication specially bleeding.
US11559325B2	Intravascular catheter having an expandable incising portion and grating tool An intravascular device is provided having an expandable portion including a plurality of struts capable of being moved between an open and a closed position. A grating tool is provided on at least one of the struts. The grating tool is configured to remove atherosclerotic material or other substances located within the blood vessel when the expandable portion is in the opened position and moved axially through the blood vessel.
US11559323B2	Surgical instrument with selector An ultrasonic instrument includes a body, an actuation assembly, a shaft assembly, and an end effector. The actuation assembly includes a mode selection member and an activation member. The shaft assembly extends distally from the body. The shaft assembly includes an acoustic waveguide. The end effector includes an ultrasonic blade. The ultrasonic blade is in acoustic communication with the acoustic waveguide. The end effector is configured to be activated in a first activation mode in response to actuation of the activation member when the mode selection member is in a first position. The end effector is configured to be activated in a second activation mode in response to actuation of the activation member when the mode selection member is in a second position.
US11559318B2	Radially-firing electrohydraulic lithotripsy probe An invasive electrohydraulic lithotripter probe may comprise a lithotripter tip that comprises a first electrode and a second electrode. The lithotripter tip has a length in excess of 250 cm and is dimensioned to be inserted into a long channel having a length in excess of 250 cm. The lithotripter probe may include a material that reinforces a linear strength of at least a portion of the lithotripter probe.
US11559316B2	Bone fixation system, assembly, implants, devices, insertion guides, and methods of use Guides, implants, devices, instruments, systems, and assemblies for achieving bone fusion are disclosed. A bone fusion system, including an implant template, a guide wire for insertion through the implant template, a bone plate for receiving the guide wire, and an alignment guide apparatus for coupling to the bone plate. Methods of using a bone fusion system for achieving bone fusion are also disclosed.
US11559314B2	Polymer cutting block including metallic protective bushings and method of using same An orthopaedic surgical instrument includes a polymer cutting block having a number of metallic cutting guides secured thereto. A pair of metallic bushings function as saw stops at the medial and lateral ends of the cutting slot during an orthopaedic surgical procedure.
US11559313B2	Radial saw blade and hub for osteotomy A saw blade includes a main body having a first surface, a second surface on an opposite side of the main body from the first surface, a proximal edge portion, a distal edge portion, and first and second side portions extending between the proximal and distal edge portions. The proximal edge portion is configured to be coupled to a rotatable hub such that the saw blade is held in a curved shape with the first surface defining an outer radius when the saw blade is coupled to the rotatable hub. The distal edge portion includes a plurality of cutting teeth, and the second surface includes a cutting structure configured such that a radius of an arc swept by the cutting structure when the saw blade is rotated is substantially equal to the outer radius of the first surface.
US11559312B2	Embolus material and method of manufacturing the same An embolic material which prevents flow of a biological fluid by being placed in a body lumen via a catheter, the embolic material comprising a material that swells by contacting the biological fluid. The embolic material includes a long filler that is formed smaller than an inner diameter of the catheter. The filler prevents the flow of the biological fluid by bending when brought into contact with the biological fluid due to the difference in swelling characteristics between a first side portion and a second side portion that extend parallel to one another in a longitudinal direction.
US11559309B2	Filamentary devices for treatment of vascular defects Devices and methods for treatment of a patient's vasculature are described. Embodiments may include a permeable implant having a radially constrained state configured for delivery within a catheter lumen, an expanded state, and a plurality of elongate filaments that are woven together. The permeable implant may include a stiffer proximal portion that is configured to sit at the neck of an aneurysm. The stiffer proximal portion may include coils, stiffening elements, or reinforcement elements disposed about or associated with the filaments or woven together with the filaments.
US11559308B2	Method for smart energy device infrastructure A method for characterizing a state of an end effector of an ultrasonic device is disclosed. The ultrasonic device including an electromechanical ultrasonic system defined by a predetermined resonant frequency. The electromechanical ultrasonic system further including an ultrasonic transducer coupled to an ultrasonic blade. The method including applying, by an energy source, a power level to the ultrasonic transducer; measuring, by a control circuit coupled to a memory, an impedance value of the ultrasonic transducer; comparing, by the control circuit, the impedance value to a reference impedance value stored in the memory; classifying, by the control circuit, the impedance value based on the comparison; characterizing, by the control circuit, the state of the electromechanical ultrasonic system based on the classification of the impedance value; and adjusting, by the control circuit, the power level applied to the ultrasonic transducer based on the characterization of the state of the end effector.
US11559307B2	Method of robotic hub communication, detection, and control Various surgical systems are disclosed. A surgical system can include a surgical robot and a surgical hub. The surgical robot can include a control unit in signal communication with a control console and a robotic tool. The surgical hub can include a display. The surgical hub can be in signal communication with the control unit. A facility can include a plurality of surgical hubs that communicate data from the surgical robots to a primary server. To alleviate bandwidth competition among the surgical hubs, the surgical hubs can include prioritization protocols for collecting, storing, and/or communicating data to the primary server.
US11559306B2	Apparatus and method to detect full seating of buttress applicator in end effector of surgical stapler An apparatus includes: (a) at least one platform configured to be positioned between opposing first and second jaws of an end effector of a surgical stapler, wherein the at least one platform is configured to transition between a first state and a second state; (b) at least one adjunct element positioned on the at least one platform; (c) at least one detector configured to detect a predetermined portion of the end effector; and (d) a driver configured to selectively transition the at least one platform from the first state to the second state in a direction toward at least one of the first or second jaws when the at least one detector detects the predetermined portion of the end effector for placing the at least one adjunct element in contact with a corresponding surface of the at least one of the first or second jaws.
US11559304B2	Surgical instrument comprising a rapid closure mechanism A surgical instrument comprising a first jaw, a second jaw rotatable relative to the first jaw, and a closure system for closing the second jaw is disclosed. The closure system comprises a multi-stage closure system. In at least one instance, the closure system comprises a first closure member which closes the second jaw quickly, but with low force, and a second closure member which closes the second jaw more slowly, but with a higher force.
US11559303B2	Cartridge lockout arrangements for rotary powered surgical cutting and stapling instruments A surgical cutting and stapling end effector. Various embodiments comprise a channel that is configured to operably support a removable staple cartridge. A rotary end effector drive shaft is supported within the channel and is configured to move a firing assembly longitudinally within the end effector to cause the sled to eject surgical staples from the staple cartridge. The firing assembly is prevented from moving distally through the channel unless a surgical staple cartridge that has a sled in a starting position has been seated within the channel.
US11559298B2	Surgical visualization of multiple targets A surgical visualization system is disclosed. The surgical visualization system is configured to identify one or more structure(s) and/or determine one or more distances with respect to obscuring tissue and/or the identified structure(s). The surgical visualization system can facilitate avoidance of the identified structure(s) by a surgical device. The surgical visualization system can comprise a first emitter configured to emit a plurality of tissue-penetrating light waves and a second emitter configured to emit structured light onto the surface of tissue. The surgical visualization system can also include an image sensor configured to detect reflected visible light, tissue-penetrating light, and/or structured light. The surgical visualization system can convey information to one or more clinicians regarding the position of one or more hidden identified structures and/or provide one or more proximity indicators.
US11559297B2	Suturing device and methods of use thereof A suturing device includes a hollow needle. The hollow needle has a length extending between a proximal end and a distal end and defining a lumen having an inner diameter. The suturing device further includes a length of surgical suture having a leading end and a trailing end and an outer diameter smaller than the inner diameter of the lumen. At least a portion of the surgical suture is located within the lumen of the hollow needle. A surgical kit including the suturing device and methods of using the suturing device of the present invention are also disclosed.
US11559296B2	Medical apparatus and method for attaching a suture to a bone A method of forming a channel in a bone, the method comprising: providing a first bore in the bone; and forming, a second bore in the bone at a predefined angle from said first bore, using said first bore as a reference point for defining the location of the second bore in the bone, wherein the first and second bores intersect in the bone.
US11559290B2	Navigable endobronchial tool to access tissue outside a bronchus Methods, systems, and devices for accessing tissue outside a bronchus and marking the location of a biopsy are provided. The method includes loading a navigation plan into a navigation system with the navigation plan including a CT volume generated from a plurality of CT images, inserting an extended working channel (EWC) including a location sensor into a patient's airways, registering a sensed location of the EWC with the CT volume of the navigation plan, and selecting a target in the navigation plan located outside the periphery of a patient's airways. The method further includes navigating the EWC and location sensor proximate the target, inserting a piercing catheter into the EWC, piercing through an airway wall to reach the target, storing a position of the location sensor in the navigation system as a biopsy location, and performing a biopsy at the stored biopsy location.
US11559289B2	Tissue handling system with reduced operator exposure A tissue handling system includes a biopsy device and a tissue storage container separate from the biopsy device. The biopsy device has a cutting cannula, a housing, and a tissue collecting device. The tissue collecting device is detachably received in the housing. The tissue collecting device is configured to receive at least one tissue sample. The tissue storage container is configured to detachably receive the tissue collecting device after the tissue collecting device is disengaged from the housing of the biopsy device to deliver the at least one tissue sample from the tissue collecting device to the tissue storage container.
US11559288B2	Portable fluid sampling device, system for using same, and method of making and using same A system for collecting and retaining a sample from exhaled breath of a subject for analysis can include a two part housing, a two part trap section, and optionally a boat fitment. Disclosed is a portable fluid sampling device comprising: a housing including a first portion removably attachable to a second portion, the first and second portions being configured to combine to form a chamber therein, the chamber being configured to at least temporarily contain or hold a biological sample therein, at least one of the first portion and the second portion including an inlet, the other of the first portion and the second portion including an outlet, wherein the device further comprises at least one of the following: a) one of the first portion and the second portion including an end having a projection, the other of the first portion and the second portion including an end having a groove, the groove being configured to receive at least a portion of the projection therein; or b) tamper evident means for indicating that the first portion of the housing has previously been separated from the second portion of the housing.
US11559281B2	CMUT heatless coded ultrasound imaging An imaging system includes transmit circuitry, a transducer array with an array of capacitive micromachined ultrasonic transducer elements, a beamformer, a decoder and a display. The transmit circuitry includes a signal generator and at least one excitation coding scheme. The transmit circuitry combines an excitation signal generated by the signal generator with an excitation coding scheme of the at least one excitation coding scheme, generating a coded excitation signal. The array of transducer elements is excited with the coded excitation signal to emit ultrasound signals. The coding scheme does not introduce heating on the capacitive micromachined ultrasonic transducer elements. The array of ultrasonic transducer elements receives echo signals produced in response to the ultrasound signals interacting with structure and generates electrical signals indicative thereof. The beamformer beamforms the electrical signals, the decoder removes the coding from the beamformed signals, and the display displays an image with the decoded signals.
US11559280B2	Ultrasound imaging system and method for determining acoustic contact An ultrasound imaging system and method includes acquiring ultrasound image data of an object while translating the ultrasound probe, where the ultrasound probe includes a scanning surface. The ultrasound imaging system and method includes displaying an acquisition view during the process of acquiring the panoramic ultrasound data. The ultrasound imaging system and method includes automatically determining acoustic contact of the scanning surface with the object while acquiring the panoramic ultrasound data and displaying a color-coded indicator at the same time as the acquisition view, where the color-coded indicator represents the acoustic contact of the scanning surface in real-time during the process of acquiring the panoramic ultrasound data.
US11559279B2	Methods and apparatuses for guiding collection of ultrasound data using motion and/or orientation data Aspects of the technology described herein relate to guiding collection of ultrasound data collection using motion and/or orientation data. A first instruction for rotating or tilting the ultrasound imaging device to a default orientation may be provided. Based on determining that the ultrasound imaging device is in the default orientation, a second instruction for translating the ultrasound imaging device to a target position may be provided. Based on determining that the ultrasound imaging device is in the target position, a third instruction for rotating or tilting the ultrasound imaging device to a target orientation may be provided.
US11559278B2	Systems and methods for vascular mapping Systems, apparatuses, methods, and non-transitory computer-readable media for mapping a section of a vasculature of a subject are described herein, including moving a probe to a first position at a body of the subject adjacent the section of the vasculature; transmitting, by the probe, a first ultrasound beam into a first portion of the section of the vasculature through the body of the subject; receiving first ultrasound data including at least one imaging parameter of the first portion based on the first ultrasound beam; moving the probe to a second position at the body of the subject adjacent the section of the vasculature and different from the first position; transmitting, by the probe, a second ultrasound beam into a second portion of the section of the vasculature through the body of the subject; receiving second ultrasound data including the at least one imaging parameter of the second portion based on the second ultrasound beam; and constructing a map of the section of the vasculature based on the first ultrasound data and the second ultrasound data.
US11559269B2	X-ray imaging apparatus, medical information processing apparatus, X-ray detector, and correction method of X-ray detector In general, an X-ray imaging apparatus according to one embodiment includes an X-ray tube, an X-ray detector, and processing circuitry. The processing circuitry is configured to obtain correction-target data that includes component deterioration resulting from a transient response of the X-ray detector, and to output, based on the obtained correction-target and a model that outputs data in which component deterioration resulting from a transient response is reduced based on an input of data that includes component deterioration resulting from a transient response, corrected data in which the component deterioration resulting from the transient response of the X-ray detector is reduced.
US11559264B2	Systems and methods to control radiation scanner positioning An example scanner positioning control system includes: a display; a processor; and a computer readable storage medium comprising computer readable instructions which, when executed, cause the processor to: output, via the display, a first visual representation of an arrangement of a radiation source, a radiation detector, and a workpiece positioner; identify a change to be made to the arrangement of at least one of the radiation source, the radiation detector, or the workpiece positioner; output, via the display, a second visual representation of the arrangement of the radiation source, the radiation detector, and the workpiece positioner based on the change to be made to the arrangement; and control a scanner positioning system to physically move the at least one of the radiation source, the radiation detector, and the workpiece positioner based on the change.
US11559261B2	Gait motion display system and program A gait motion display system including: a triaxial accelerometer, attached to the subject, that measures acceleration data of a subject in walking; an imaging unit that takes images of the subject in walking to obtain moving image data showing gait motions of the subject; a recording unit that records the acceleration data and the moving image data in synchronization with each other; an identification unit that converts the acceleration data recorded by the recording unit into horizontal displacement data and vertical displacement data, and identifies, from the moving image data, a representative image corresponding to a representative motion in a gait cycle, based on the horizontal displacement data or the vertical displacement data; and a display that displays an image illustration of the representative motion in the gait cycle, with the representative image identified by the identification unit.
US11559260B2	Systems and methods for processing analyte sensor data The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for processing sensor data, including calculating a rate of change of sensor data and/or determining an acceptability of sensor or reference data.
US11559259B2	Patient securing overlay for underbody supports Apparatus and methods related to an underbody support for supporting a body of a being, such as during surgery to prevent contact pressure injuries. In certain embodiments, the underbody support may include one or more inflatable chambers enclosing a volume. At least one of the inflatable chambers may include one or more compression sensitive switches for monitoring the volume of the inflatable chamber, and the one or more compression sensitive switches may be located within the inflatable chamber. In some embodiments the one or more compression sensitive switches are sized to close when the said inflatable chamber is deflated to a desired residual volume.
US11559252B2	Hearing assistance device incorporating virtual audio interface for therapy guidance A hearing assistance device adapted to be worn by a wearer comprises a processor configured to generate a sequence of audio cues that audibly guide the wearer through a series of actions involving the wearer's head and neck in accordance with a predetermined corrective or therapeutic maneuver. A speaker is configured to play back the sequence of audio cues for reception by the wearer. One or more sensors are configured to sense movement of the head during each of the actions. The processor is configured to determine if head movement for an action associated with each audio cue has been correctly executed by the wearer, and produce an output indicative of successful or unsuccessful execution of the actions by the wearer.
US11559250B1	High sensitivity movement disorder treatment device or system The present invention relates to a movement disorder monitor with high sensitivity, and a method of measuring the severity of a subject's movement disorder. The present invention additionally relates to a drug delivery system for dosing a subject in response to the increased severity of a subject's symptoms. The present invention provides for a system and method, which can accurately and repeatably quantify symptoms of movements disorders, accurately quantifies symptoms utilizing both kinetic information and/or electromyography (EMG) data, that can be worn continuously to provide continuous information to be analyzed as needed by the clinician, that can provide analysis in real-time, that allows for home monitoring of symptoms in subject's with these movement disorders to capture the complex fluctuation patterns of the disease over the course of days, weeks or months, that maximizes subject safety, and that provides substantially real-time remote access to data by the clinician or physician.
US11559244B2	System and methods for consciousness evaluation in non-communicating subjects Disclosed is a method for the generation of a consciousness indicator for a non-communicating subject, including the steps of generating an auditory stimulation, receiving an electrocardiographic signal of the subject obtained from a recording during the generation of the auditory stimulation, extracting at least one feature from the electrocardiographic signal and deducing a consciousness indicator from an analysis of the electrocardiographic feature.
US11559243B2	System and method for evaluating neurological conditions In described embodiments, a device and method for diagnosing brain and neurological issues is provided. The device measures the performance of Convergence, Divergence, and binocular tracking capabilities of a subject's eyes, which can be used to determine whether a subject has experienced a brain or other neurological event.
US11559242B2	Methods and systems for distinguishing over-sensed R-R intervals from true R-R intervals Described herein are methods, devices, and systems that monitor heart rate and/or for arrhythmic episodes based on sensed intervals that can include true R-R intervals as well as over-sensed R-R intervals. True R-R intervals are initially identified from an ordered list of the sensed intervals by comparing individual sensed intervals to a sum of an immediately preceding two intervals, and/or an immediately following two intervals. True R-R intervals are also identified by comparing sensed intervals to a mean or median of durations of sensed intervals already identified as true R-R intervals. Individual intervals in a remaining ordered list of sensed intervals (from which true R-R intervals have been removed) are classified as either a short interval or a long interval, and over-sensed R-R intervals are identified based on the results thereof. Such embodiments can be used, e.g., to reduce the reporting of and/or inappropriate responses to false positive tachycardia detections.
US11559238B2	Ambulatory medical device including a digital front-end An ambulatory medical device including a plurality of sensing electrodes and one or more processors operably coupled to the plurality of sensing electrodes is provided. Each sensing electrodes is configured to be coupled eternally to a patient and to detect one or more ECG signals. The one or more processors are configured to receive at least one electrode-specific digital signal for each of the plurality of sensing electrodes, determine a noise component for each of the electrode-specific digital signals, analyze each of the noise components for each of the plurality of sensing electrodes, generate electrode matching information for each sensing electrode of the plurality of sensing electrodes based upon analysis of each of the noise components, determine one or more sensing electrode pairs based upon the electrode matching information, and monitor each of the one or more sensing electrode pairs for ECG activity of the patient.
US11559230B2	Systems, devices, and methods to compensate for temperature effects on sensors This document discusses, among other things, systems and methods to compensate for the effects of temperature on sensors, such as analyte sensor. An example method may include determining a temperature-compensated glucose concentration level by receiving a temperature signal indicative of a temperature parameter of an external component, receiving a glucose signal indicative of an in vivo glucose concentration level, and determining a compensated glucose concentration level based on the glucose signal, the temperature signal, and a delay parameter.
US11559220B2	Measurement unit for measuring a bio-impedance A measurement unit for measuring a bio-impedance of a body, the measurement unit comprising a current generator circuit, a readout circuit, and a baseline cancellation current circuit, wherein the current generator circuit is configured to amplify a reference current to form a measurement current to be driven through a body to generate a measurement voltage representing the bio-impedance; wherein the readout circuit comprises a Instrumentation amplifier (IA) which has a transconductance stage and a transimpedance stage, wherein the IA is configured to: produce a first current in the transconductance stage, the first current being proportional to the measurement voltage, receive a second current from the baseline cancellation current circuit, produce an output voltage in the transimpedance stage, the output voltage being proportional to a difference between the first current and the second current and representative of the measured bio-impedance; wherein the baseline cancellation current circuit is configured to amplify the reference current by a factor to form the second current and deliver it to the IA, wherein the factor is such that that the absolute value of the difference between the first and the second current is below a threshold such that a baseline of the first current is cancelled by the second current.
US11559218B2	Intravascular pressure and flow data diagnostic systems, devices, and methods In part, the disclosure relates to computer-based methods, devices, and systems suitable for performing intravascular data analysis and measurement of various types of data such as pressure and flow data. The disclosure relates to probes and methods suitable for determining an event in a cardiac cycle such as flow threshold such as a peak flow, a fraction thereof, other intravascular parameters or a point in time during which peak flow or a change in one of the parameters occurs. An exemplary probe includes one or more of a pressure sensor, a resistor, a flow sensor and can be used to generate diagnostic data based upon measured intravascular and other parameters. In part, the disclosure relates to methods and systems suitable for determining a coronary flow reserve value in response to one or more of intravascular pressure and flow data or data otherwise correlated therewith.
US11559217B2	Multi sensor radio frequency detection Radio frequency motion sensors may be configured for operation in a common vicinity so as to reduce interference. In some versions, interference may be reduced by timing and/or frequency synchronization. In some versions, a master radio frequency motion sensor may transmit a first radio frequency (RF) signal. A slave radio frequency motion sensor may determine a second radio frequency signal which minimizes interference with the first RF frequency. In some versions, interference may be reduced with additional transmission adjustments such as pulse width reduction or frequency and/or timing dithering differences. In some versions, apparatus may be configured with multiple sensors in a configuration to emit the radio frequency signals in different directions to mitigate interference between emitted pulses from the radio frequency motion sensors.
US11559215B2	Method for measuring high-accuracy realtime heart rate based on continuous-wave Doppler radar and radar system therefor A method for measuring a high-accuracy and real-time heart rate based on a continuous-wave radar is provided. The method includes receiving an in-phase (I) signal and a quadrature (Q) signal for a receive signal received through the continuous-wave radar, selecting any one signal by comparing magnitudes of the received I signal and the received Q signal, performing frequency transform of each of bases respectively having predetermined phases with respect to the any one selected signal, and determining a heart rate based on a magnitude response of each of the bases by the frequency transform.
US11559210B2	Methods and apparatus to estimate ventricular pressure An approach for determining an estimated pressure curve for the ventricle of the heart, the method comprising: using data from a motion sensor that has been implanted at the heart to determine the timing of heart cycle events; scaling a reference pressure-time curve including timing of reference heart cycle events in order to fit the reference pressure-time curve to the motion sensor data, the scaling comprising scaling the reference curve along the time axis to fit it to the measured timing of the heart cycle events; and thereby obtaining an estimated pressure-time curve in the form of the scaled reference pressure-time curve.
US11559207B2	Rotational intravascular devices, systems, and methods utilizing photoacoustic and ultrasound imaging techniques Imaging devices, systems, and methods are provided. Some embodiments of the present disclosure are particularly directed to imaging a region of interest in tissue with photoacoustic and ultrasound modalities. In some embodiments, a medical sensing system (100) includes a measurement apparatus (102) configured to be placed within a vascular pathway. The measurement apparatus may include a sensor array (106) comprising two or more sensor modalities. The sensor array may be configured to receive sound waves created by the interaction between emitted optical pulses and tissue, transmit and receive ultrasound signals, and rotate around a longitudinal axis of the measurement device. The medical sensing system may also include a processing engine operable to produce images of the region of interest and a display configured to visually display the image of the region of interest.
US11559203B2	Noninvasive in vivo measurement of pH in cerebrospinal fluid A system and method for determining the pH of tissue in vivo. A Raman spectrometer is used to collect Raman spectra from the target tissue. The Raman spectra are baseline subtracted and assessed to determine the concentration of HPO4−2 and H2PO4−1 for the purposes of calculating the pH. The approach was validate in vitro using PBS solutions of known pH. The approach was confirmed in vivo using rat and swine models by probing the immediate vicinity of a contusive spinal cord injury (SCI) in the first minutes and hours after injury. Using a dynamic analysis and the Henderson-Hasselbalch equation, the average of (N=12) noninvasive Raman-based pH measurements of CSF was 7.073±0.156 and at >95% confidence there is no statistically significant difference between the Raman-based and the physically sampled results.
US11559202B2	System for integrally measuring clinical parameters of visual function System for integrally measuring clinical parameters of the visual function including a display unit (20) for representing a scene with a 3D object having variable characteristics such as virtual position and virtual volume of the 3D object within the scene; movement sensors (60) for detecting the user head position and distance from the display unit (20); tracking sensors (10) for detecting the user pupils position and pupillary distance; an interface (30) for the user interaction on the scene; processing means (42,44) for analysing the user response based on the data coming from sensors (60,10) and the interface (30), with the characteristics variations of the 3D object; and based on the estimation of a plurality of clinical parameters of the visual function related to binocularity, accommodation, ocular motility and visual perception.
US11559201B1	Systems and methods for eye tracking using modulated radiation Eye-tracking systems of the present disclosure may include at least one light source configured to emit modulated radiation toward an intended location for a user's eye. The modulated radiation may be modulated in a manner that enables the light source to be identified by detection and analysis of the modulated radiation. At least one optical sensor including at least one sensing element may be configured to detect at least a portion of the modulated radiation. A processor may be configured to identify, based on the modulated radiation detected by the optical sensor, the light source that emitted the modulated radiation. Various other methods, systems, and devices are also disclosed.
US11559198B2	Medical interfaces and other medical devices, systems, and methods for performing eye exams A mask for performing an eye exam of a subject includes one or more optically transparent sections for transmitting an incident light beam therethrough and incident on the subject's eye. In some embodiments, the one or more optically transparent sections are coated with an anti-reflective coating configured to reduce reflection of the incident light beam by the one or more optically transparent sections. In some embodiments, the one or more optically transparent sections may have a portion thereof that is tilted with respect to the incident light beam when the mask is optically interfaced with the docking portion of an ophthalmic instrument, such that the incident light beam forms a finite angle of incidence with respect to the corresponding portion of the optically transparent sections.
US11559195B2	Rigid endoscope cover and endoscope unit A cover 20 for covering a circumferential portion of an outer circumferential surface of a rigid endoscope 10 having an observation window portion 14 provided at a tip thereof includes a flexible outer cover member 22 covering the circumferential portion of the circumferential surface of the rigid endoscope 10 and a tubular member 26, provided inside the outer cover member 22, through which a cleaning fluid to be supplied from a base end of the rigid endoscope 10 to the observation window portion 14 of the rigid endoscope 10 flows inside, and the outer cover member 22 is attached to the outer circumference surface of the rigid endoscope 10 by flexing the outer cover member 22.
US11559191B2	Insertion unit for medical instruments and an intubation system thereof The present invention discloses an insertion unit, a bending section and an intubation system for use in a body lumen of a patient. The insertion unit comprises an inner elongated shaft structure being capable of torque transmission around its length axis and having spring-like and flexibility properties and an outer elongated shaft structure at least partially surrounding the inner elongated shaft structure and having spring-like properties and a continuous and flat outer surface. The inner elongated shaft structure has a distal end, and is capable of being connected to an optical head. The insertion unit is configured to transmit pushing and rotation forces along a length of the insertion unit. The integral insertion unit is configured and operable to bend the distal tip in all directions and to fully rotate the distal tip.
US11559189B2	Sterile sheath for confocal endomicroscopy scanner probe A sterile sheath and methods for enclosing a confocal endomicroscopy (CEM) scanner probe with the sterile sheath are provided. The scanner probe includes a probe shaft, a probe tip, a probe body, and a probe umbilical. The sterile sheath for enclosing the CEM scanner probe includes a sheath tube configured to receive the probe shaft and has a distal tube end, a proximal tube end, a sheath tip mounted at the distal tube end of the sheath tube, and a sheath socket configured to receive the probe body. The sheath socket has a distal socket end and a proximal socket end. The proximal tube end of the sheath tube is fixed to the sheath socket at the distal socket end. The sterile sheath further includes a sheath lock ring and a sheath drape mounted on the sheath socket at the proximal socket end with the sheath lock ring.
US11559188B2	Off-axis visualization systems A system for visualizing a tissue region of interest comprises a deployment catheter defining a lumen and a hood coupled to and extending distally from the deployment catheter. The hood has a low-profile configuration within a delivery sheath and a deployed configuration when extended distally of the delivery sheath. The hood in the deployed configuration defines an open area in fluid communication with the lumen. A distal portion of the deployment catheter extends into the open area. An imaging element is coupled to an imager support member. When in the deployed configuration, the imaging element is configured to extend distally of the distal portion while the imager support member extends within the deployment catheter. The imaging element comprises a tapered surface and the deployment catheter comprises a complementary tapered surface. Retraction of the imaging element causes the imaging element to shift radially outward from a longitudinal axis.
US11559186B2	Evaluation value calculation device and electronic endoscope system An electronic endoscope system includes a plotting unit which plots pixel correspondence points, which correspond to pixels that constitute a color image that has multiple color components, on a first color plane according to color components of the pixel correspondence points, the first color plane intersecting the origin of a predetermined color space; an axis setting unit which sets a predetermined reference axis in the first color plane; a transform unit which defines a second color plane that includes the reference axis, and subjecting the pixel correspondence points on the first color plane to projective transformation onto the second color plane; and an evaluation value calculating unit which calculates a prescribed evaluation value with respect to the color image based on the pixel correspondence points subjected to projective transformation onto the second color plane.
US11559178B1	Defecation postural modification devices A stationary children's toilet assembly may include a potty with a pedaling mechanism (e.g., one or more cycling pedals) coupled thereto that together may act as a defecation postural modification device by raising a child's legs up and increasing hip flexion during user, which may support proper squatting posture and aid elimination.
US11559177B2	Dryer stand A dryer stand for mounting a dryer for discharging air, including a stem, a base, a receptacle on which the dryer is mounted, a moving apparatus including a rotation motor and connected to the receptacle, and a controller. The controller enables the position of the receptacle to be changed or returned by controlling the forward and backward rotation of the rotation motor so that the receptacle is moved in a given direction when a position change command for the receptacle is received and the receptacle returns to its original position when a position return command for the receptacle is received.
US11559176B2	Dryer stand A dryer stand including a seat to receive a dryer thereon, a base spaced apart from the seat downward, a side cover forming a side appearance between the base and the seat, and a light positioned in an internal space defined by the side cover.

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