Document Document Title
US11560660B2 Laundry treating apparatus
In a laundry treating apparatus, flat surfaces are installed at both sides of a tub for storing water therein, so that a spacing between each of the both sides of the tub and each side of a cabinet is smaller than a spacing between a lower surface of the tub and a bottom of the cabinet. Further, a control panel is disposed between the lower surface of the tub and the bottom of the cabinet.
US11560659B2 Washing machine and control method of same
A washing machine of the present disclosure includes: a tub in which water is stored; a drum which is rotatably provided in the tub, and accommodates laundry; and a detergent supply device which supplies a liquid additive to the tub, wherein the detergent supply device includes: a cartridge which contains the additive; a pump which extracts the additive contained in the cartridge; an outlet flow path pipe which is connected to the cartridge, and through which the extracted additive flows toward the tub; and a flow path pipe sensor which is installed in the outlet flow path pipe, and detects an existence of the additive in the outlet flow path pipe.
US11560651B2 Compression fabrics with tailored comfort
Certain embodiments according to the invention provide compression articles suitable for a wide variety of uses (e.g., compression socks, athletic garments, etc.). In accordance with certain embodiments, the compression article includes at least two uniform compression regions, including a first uniform compression region having a first compression pressure and a second uniform compression region having a second compression pressure, and at least one transitioning compression region, including a first transitioning compression region positioned between the first and second uniform compression regions. The first transitioning compression region comprises a first end adjacent or proximate to the first uniform compression region and a second end adjacent or proximate to the second uniform compression region. The first transitioning compression region comprises a compression pressure gradient extending from the first end to the second end of the first transitioning compression region.
US11560643B2 System for efficient manufacturing of a plurality of high-quality semiconductor single crystals by physical vapor transport
A system for simultaneously manufacturing more than one single crystal of a semiconductor material by physical vapor transport (PVT) includes a plurality of reactors and a common vacuum channel connecting at least a pair of reactors of the plurality of reactors. Each reactor has an inner chamber adapted to accommodate a PVT growth structure for growth of a single semiconductor crystal. The common vacuum channel is connectable to a vacuum pump system for creating and/or controlling a common gas phase condition in the inner chambers of the pair of reactors.
US11560642B2 Apparatus for an inert anode plating cell
In one example, an electroplating apparatus is provided for electroplating a wafer. The electroplating apparatus comprises a wafer holder for holding a wafer during an electroplating operation and a plating cell configured to contain an electrolyte during the electroplating operation. An anode chamber is disposed within the plating cell, and a charge plate is disposed within the anode chamber. An anode is positioned above the charge plate within the anode chamber. In some examples, the anode chamber is a membrane-less anode chamber.
US11560638B2 Electrochemical method of ammonia generation
An electrolysis apparatus for producing ammonia, the apparatus comprising: a cathode; an anode; an electrolyte; a current source; a supply for nitrogen; and a supply for an acid, wherein the acid comprises at least one acid selected from the group consisting of: HCl, HBr, and HI.
US11560634B2 Integrally combined current carrier circulation chamber and frame for use in unipolar electrochemical devices
Disclosed is an integrally combined electrical current carrier, circulation chamber and frame (CCF) formed as a single or double part (CCF) for use in unipolar electrochemical devices, such as a filter press electrolyser apparatus. The CCF is structured to define an internal circulation chamber for circulation of electrolyte, products, and reactants as well as apertures which form flow passageways when the filter press device is assembled. Affixed on opposed surfaces of the CCFs are electrically conductive planar electroactive structures which are in electrical contact with the CCF. The circulation chamber is formed by the depth of the CCF itself between opposing electroactive structures. Multiple CCFs are assembled and compressed together to form the filter press electrolyser apparatus. The flow passageway apertures within the assembled filter press electrolyser are aligned to form flow pathways, located above and below the circulation chambers. Reactants and electrolyte are input along the bottom flow pathways. When power is applied to the CCFs and electroactive structures, the reactants, once they flow into the circulation chamber with the electrolyte, undergo redox reactions to produce the products which are then collected and exit the electrolyser in the upper flow pathways.
US11560633B2 Electrochemical production of carbon monoxide and/or syngas
An electrolysis system and an electrolysis method wherein the electrolysis system includes a pressure-electrolytic cell and a throttle in the catholyte line, by which the catholyte flow can be divided into a gas and liquid phase. In this way, (by-)products of the electrolysis can be recycled, while the electrolytic cell can be operated effectively at a high pressure.
US11560632B2 Membrane, membrane electrode assembly, and water electrolyzer including the same
A water electrolyzer comprises a membrane, a cathode and an anode. The membrane comprises a first membrane layer comprising a first ion-conductive polymer, a second membrane layer comprising a second ion-conductive polymer, and a platinized nanostructured layer disposed between the first layer and the second layer. The platinized nanostructured layer comprises close-packed whiskers having at least one of platinum or platinum oxide disposed thereon. The cathode is disposed on the membrane and comprises a first catalyst consisting essentially of both metallic Pt and Pt oxide. The anode is disposed on the opposite surface of the membrane and comprises a second catalyst comprising at least 95 percent by weight of collectively metallic Ir and Ir oxide, calculated as elemental Ir, based on the total weight of the second catalyst, wherein at least one of metallic Ir or Ir oxide is present. Membranes and methods of making them are also disclosed.
US11560631B2 Electrochemical production of graphene sheets from coke or coal
A method of producing graphene sheets from coke or coal powder, comprising: (a) forming an intercalated coke or coal compound by electrochemical intercalation conducted in an intercalation reactor, which contains (i) a liquid solution electrolyte comprising an intercalating agent; (ii) a working electrode that contains the powder in ionic contact with the liquid electrolyte, wherein the coke or coal powder is selected from petroleum coke, coal-derived coke, meso-phase coke, synthetic coke, leonardite, lignite coal, or natural coal mineral powder; and (iii) a counter electrode in ionic contact with the electrolyte, and wherein a current is imposed upon the working electrode and the counter electrode for effecting electrochemical intercalation of the intercalating agent into the powder; and (b) exfoliating and separating graphene planes from the intercalated coke or coal compound using an ultrasonication, thermal shock exposure, mechanical shearing treatment, or a combination thereof to produce isolated graphene sheets.
US11560628B2 Substrate processing method and substrate processing apparatus
A substrate processing method includes supplying processing gas from a plurality of gas holes formed along a longitudinal direction of an injector, which extends in a vertical direction along an inner wall surface of a processing container and is rotatable around a rotational axis extending in the vertical direction, to perform a predetermined process on a substrate accommodated in the processing container. The predetermined process includes a plurality of operations, and a supply direction of the processing gas is changed by rotating the injector in accordance with the operations.
US11560627B2 Atmospheric cold plasma jet coating and surface treatment
A system and method are described for depositing a material onto a receiving surface, where the material is formed by use of a plasma to modify a source material in-transit to the receiving surface. The system comprises a microwave generator electronics stage. The system further includes a microwave applicator stage including a cavity resonator structure. The cavity resonator structure includes an outer conductor, an inner conductor, and a resonator cavity interposed between the outer conductor and the inner conductor. The system also includes a multi-component flow assembly including a laminar flow nozzle providing a shield gas, a zonal flow nozzle providing a functional process gas, and a source material flow nozzle configured to deliver the source material. The source material flow nozzle and zonal flow nozzle facilitate a reaction between the source material and the functional process gas within a plasma region.
US11560625B2 Vapor deposition of molybdenum using a bis(alkyl-arene) molybdenum precursor
Described are vapor deposition methods for depositing molybdenum materials onto a substrate by the use of bis(alkyl-arene) molybdenum, also referred to herein as (alkyl-arene)2Mo, for example bis(ethyl-benzene) molybdenum ((EtBz)2Mo), as a precursor for such deposition, as well as structures that contain the deposited material.
US11560617B2 Structurally-colored articles and methods for making and using structurally-colored articles
As described above, one or more aspects of the present disclosure provide articles having structural color, and methods of making articles having structural color.
US11560616B2 Mask device, mask plate, and frame
A mask device, a mask plate and frame are provided. The mask device includes a frame and a first mask plate. The frame includes an inner edge, an outer edge, and a plurality of mounting grooves. A first mask plate includes a substrate, at least one first mask opening on the substrate, and a plurality of clamping portions protruding and extending outward from at least part of a periphery of the substrate. The plurality of clamping portions are mounted in the plurality of mounting grooves, respectively, so that the substrate is mounted on the inner edge of the frame. A direction along which the clamping portion extends from the substrate to a direction away from the substrate is a first direction, a direction perpendicular to the first direction is a second direction.
US11560612B2 Method for producing a low-alloy steel ingot
A method of fabricating a low alloy steel ingot, the method including a) melting all or part of an electrode by a vacuum arc remelting method, the electrode, before melting, including iron and carbon, the melted portion of the electrode being collected in a crucible, thus forming a melt pool within the crucible; and b) solidifying the melt pool by heat exchange between the melt pool and a cooling fluid, the heat exchange applied serving to impose a mean solidification speed during step b) that is less than or equal to 45 μm/s and to obtain an ingot of low alloy steel.
US11560611B2 Cutting tool with PCD inserts, systems incorporating same and related methods
A cutting tool which may be used in machining various material may include a body and one or more cutting elements associated therewith. In one example, the cutting element(s) may comprise a superhard table, such as a polycrystalline diamond table. In some embodiments, the polycrystalline diamond table may have a diamond density of approximately 95 percent volume or greater. In some embodiments, the thickness of the superhard table may be approximately 0.15 inch. In some embodiments, the superhard table may include a chip breaking feature or structure. Methods of shaping, finishing or otherwise machining materials are also provided, including the machining of materials comprising titanium.
US11560605B2 High yield strength steel with mechanical properties maintained or enhanced via thermal treatment optionally provided during galvanization coating operations
This disclosure is related to high yield strength steel where mechanical properties, such as elongation, ultimate tensile strength and yield strength in a sheet are maintained or enhanced via thermal treatment optionally provided during a galvanization coating operation.
US11560603B2 Grain-oriented electrical steel sheet and method for manufacturing same
Provided is a grain-oriented electrical steel sheet that has excellent magnetic properties and can be manufactured by secondary recrystallization orientation control using coil annealing with high productivity. A grain-oriented electrical steel sheet comprises a specific chemical composition, wherein an average value of a deviation angle (α2+β2)1/2 calculated from a deviation angle α from ideal Goss orientation around an ND rotation axis and a deviation angle β from ideal Goss orientation around a TD rotation axis is 5.0° or less, and an area ratio Rβ of crystal grains with β≤0.50° is 20% or less.
US11560600B2 Methods for diagnosis of Pseudoperonospora cubensis infection and selection of plant resistance genes to the same
The invention is directed to methods of diagnosing a Pseudoperonospora cubensis infection in a cucurbit plant, comprising detecting at least one nucleotide sequence selected from the group of nucleotide sequences of SEQ ID NOs: 1-52, or any combination thereof, in a sample from a cucurbit plant or in an environmental sample, thereby diagnosing a P. cubensis infection. Also provided is a method of selecting a cucurbit plant comprising at least one resistance gene, the method comprising introducing into the cucurbit plant a nucleotide sequence of any one of SEQ ID NOs: 1-52, wherein the expression of the nucleotide sequence produces a hypersensitive response in a cucurbit plant comprising a resistance gene, thereby identifying the cucurbit plant as comprising a resistance gene; and selecting the plant having the hypersensitive response and identified as comprising said resistance gene.
US11560598B2 Systems and methods for analyzing circulating tumor DNA
The invention provides oncogenomic methods for detecting tumors by identifying circulating tumor DNA. A patient-specific reference directed acyclic graph (DAG) represents known human genomic sequences and non-tumor DNA from the patient as well as known tumor-associated mutations. Sequence reads from cell-free plasma DNA from the patient are mapped to the patient-specific genomic reference graph. Any of the known tumor-associated mutations found in the reads and any de novo mutations found in the reads are reported as the patient's tumor mutation burden.
US11560596B2 Method for expecting and diagnosing UQCRB-related disease
Disclosed is a method for expecting and diagnosing UQCRB-related disease, and more particularly, related to a method for diagnosing a UQCRB-related disease and a cholesterol biosynthesis related disease, as well as expecting risks of post-occurrence of the UQCRB-related disease and the cholesterol biosynthesis related disease, simply by measuring an expression level of miRNA, and a kit and a biomarker composition for the method.
US11560592B2 Method for resetting an array
Provided herein are methods for resetting an array to which a biological sample has been applied that include treating the array with a set of biological sample removal conditions.
US11560591B2 Analytic device comprising a substrate, nanometer-scale wells, and shallow waveguide optically coupled to a deep waveguide
This invention provides devices for use in various analytical applications including single-molecule analytical reactions. Methods for detecting analytes optically by propagating optical energy by waveguides within a substrate are provided. Analytical devices are provided which have both shallow and deep waveguides in which illumination light is transported through the deep waveguides and coupled into the shallow waveguides. The shallow waveguides provide evanescent field illumination to analytes, such as single-molecule analytes, within nanometer scale wells. Integrated devices including integrated detectors such as CMOS detectors are included.
US11560589B2 Enzyme stalling method
The invention relates to new methods of moving helicases past spacers on polynucleotides and controlling the loading of helicases on polynucleotides. The invention also relates to new methods of characterising target polynucleotides using helicases.
US11560584B2 Phage-mediated immunoassay and methods for determining susceptibility of bacteria to antibiotic or probiotic agents
Methods for determining the susceptibility or resistance of bacteria to antibiotic agents are provided. In one embodiment, the methods include culturing the bacteria in the presence or absence or the antimicrobial agent to generate a primary culture which is then cultured in the presence or absence of transforming phages. The recombinant phages are specific to the bacteria and comprise a heterologous marker (e.g., a nucleic acid that is expressible as a detectable product such as an RNA or a protein). The susceptibility or resistance of the bacteria to the antimicrobial agent may be determined by assaying the culture for the presence or absence of the heterologous marker, wherein a reduction in the level or activity of the marker in the culture compared to the level or activity of the marker in a comparative culture indicates that the bacteria is sensitive to the antibiotic agent.
US11560578B2 Neopinone isomerase and methods of using
Disclosed are methods for converting a first morphinan alkaloid compound into a second morphinan alkaloid compound in the presence of a neopinone isomerase enzyme under reaction conditions permitting the conversion of the first alkaloid compound into the second alkaloid compound. The first alkaloid compound can be neopinone or neomorphinone. The second alkaloid compound can be codeinone or morphinone. Related compositions are also disclosed.
US11560576B1 Methods of producing lipid-derived compounds and host cells thereof
The present disclosure relates to genetically engineered host cells and methods of producing a lipid-derived compound by employing such host cells. In particular embodiments, the host cell includes a first mutant gene encoding a cytoplasmic tRNA thiolation protein. Optionally, the host cell can include other mutant genes for decreasing fatty alcohol catabolism, decreasing re-importation of secreted fatty alcohol, or displaying other useful characteristics, as described herein.
US11560575B2 High efficient delivery of plasmid DNA into human and vertebrate primary cells in vitro and in vivo by nanocomplexes
The present invention includes synthesis of polyethyleneimine800-EpoxyC8-22 (PEI800-C8-22) lipids, e.g., Polyethyleneimine800-EpoxyC16 (PEI800-C16), PEI12C16, PEI8C16, and PEI4C16 lipids, compositions and methods for transfecting primary leukocytes, myeloid cells, lymphoid cells, monocytes, macrophages and dendritic cells (DC) comprising a transfection complex comprising: one or more nanoparticles; and Polyethyleneimine800-EpoxyC16 (PEI800-C16), PEI12C16, PEI8C16, and PEI4C16 lipids complexed with one or more nucleic acids, such as, e.g., DNA, RNA, nucleic acid vectors, shRNA, miRNA, and RNAi on or about the nanoparticles.
US11560574B2 Methods and compositions for selective regulation of protein expression
The invention provides methods and compositions for selectively suppressing the expression of a recombinant protein in a male reproductive tissue of a transgenic plant. The invention also provides methods and compositions for inducing male sterility in a transgenic plant. Plants, plant cells, plant parts, seeds, and commodity products including such compositions are aspects of the invention.
US11560568B2 Generation of site-specific-integration sites for complex trait loci in corn and soybean, and methods of use
Compositions and methods are provided for introducing transgenic target sites for Site Specific Integration (SSI) and/or polynucleotides of interest into at least one double-strand break target site of a double-strand-break inducing agent in a genomic window of a plant genome. Also provided are methods and compositions for producing a complex trait locus in a genomic window of a plant comprising at least one transgenic target site for site specific integration integrated in at least double-strand-break target site. The double-strand-break target site can be, but is not limited to, a target site for a zinc finger endonuclease, an engineered endonuclease, a meganuclease, a TALENs and/or a Cas endonuclease. The genomic window of said plant can comprise at least one genomic locus of interest such as a trait cassette, a transgene, a mutated gene, a native gene, an edited gene or a site-specific integration (SSI) target site.
US11560566B2 Aptazyme-embedded guide RNAs for use with CRISPR-Cas9 in genome editing and transcriptional activation
Some aspects of this disclosure provide compositions, methods, systems, and kits for controlling the activity and/or improving the specificity of RNA-programmable proteins, such as Cas9. For example, provided are guide RNAs (gRNAs) that are engineered to exist in an “on” or “off” state, which control the binding and, in certain instances, cleavage activity of RNA-programmable proteins (e.g., RNA-programmable endonucleases). By incorporating ligand-responsive self-cleaving catalytic RNAs (aptazymes) into guide RNAs, a set of aptazyme-embedded guide RNAs was developed that enable small molecule-controlled nuclease-mediated genome editing and small molecule-controlled base editing, as well as small molecule-dependent transcriptional activation in mammalian cells.
US11560563B2 SiRNAs with vinylphosphonate at the 5′ end of the antisense strand
The present invention relates to nucleic acids for inhibiting expression of a target gene in a cell, comprising at least one duplex region that comprises at least a portion of a first strand and at least a portion of a second strand that is at least partially complementary to the first strand, wherein said first strand is at least partially complementary to at least a portion of RNA transcribed from said target gene to be inhibited. The first strand of the nucleic acid has a terminal 5′ (E)-vinylphosphonate nucleotide that is linked to the second nucleotide in the first strand by a phosphodiester linkage.
US11560559B2 Inducing production of full-length progranulin (GRN) from nucleotides including mutations containing a premature stop codon (PTC)
Disclosed herein are methods for inducing production of full-length progranulin (GRN) from a nucleotide encoding a GRN with a premature stop codon (GRN-PTC), comprising exposing the GRN-PTC to an aminoglycoside. Methods for inducing production of full-length progranulin (GRN) from a nucleotide encoding a GRN with a premature stop codon (GRN-PTC), comprising administering gentamicin or G418 is also disclosed.
US11560558B2 Methods of capturing cell-free methylated DNA and uses of same
There is described herein, a method of capturing cell-free methylated DNA from a sample having less than 100 mg of cell-free DNA, comprising the steps of: subjecting the sample to library preparation to permit subsequent sequencing of the cell-free methylated DNA; adding a first amount of filler DNA to the sample, wherein at least a portion of the filler DNA is methylated; denaturing the sample; and capturing cell-free methylated DNA using a binder selective for methylated polynucleotides.
US11560552B2 Polymerases, compositions, and methods of use
Presented herein are altered polymerase enzymes for improved incorporation of nucleotides and nucleotide analogues, in particular altered polymerases that maintain high fidelity under reduced incorporation times, as well as methods and kits using the same.
US11560549B2 Integration sites in CHO cells
The present invention relates to the identification of a genomic integration site for heterologous polynucleotides in Chinese Hamster Ovary (CHO) cells resulting in high RNA and/or protein production. More specifically it relates to CHO cells comprising at least one heterologous polynucleotide stably integrated into the S100A gene cluster of the CHO genome and to methods for the production of said CHO cells. Further, the invention relates to a method for the production of a protein of interest using said CHO cell and to the use of said CHO cell for producing a protein of interest at high yield. Integration within these specific target regions leads to reliable, stable and high yielding production of an RNA and/or protein of interest, encoded by the heterologous polynucleotide.
US11560547B2 Methods of making T cell compositions
The invention provides improved T cell compositions and methods for manufacturing T cells. More particularly, the invention provides methods of T cell manufacturing that result in adoptive T cell immunotherapies with improved survival, expansion, and persistence in vivo.
US11560545B2 Polymeric carriers and methods
Provided are methods of controlling disassociation of cells from a carrier, compositions, and methods of collecting cells. The methods of controlling disassociation of cells from a carrier may include contacting a polymeric carrier with one or more digesting agents to disassociate at least a portion of a plurality of cells from the polymeric carrier. The polymeric carrier may be crosslinked with a crosslinker including at least one of a redox sensitive moiety, a UV light sensitive moiety, a pH sensitive moiety, and a temperature sensitive moiety.
US11560544B2 Isolation and pure culture of an archaebacterium of order Methanomassiliicoccales
The present invention concerns a process for isolating an archaeon of the order of commensal clade Methanomassiliicoccales, the use of a culture and/or isolation medium comprising a sterile extract of a bacterial culture of a bacterium of genus Eggerthella, for the isolation and/or culture of an archaeon of the order of commensal clade Methanomassiliicoccales, and a pure, isolated archaeon Methanomethylophilus alvus Mx-05. It also concerns a culture method of an archaeon of the order of commensal clade Methanomassiliicoccales.
US11560542B2 Process for producing phycocyanin-rich biomass via URA culturing
The invention relates to the cultivation of unicellular red algae (URA) for producing biomass for the production of products of interest, such as dry biomass or compounds or mixtures of compounds of interest extracted from the biomass produced, particularly food pigments or colouring agents. The invention more particularly relates to the industrial production of said biomass, which must satisfy an economic equilibrium of profitability, with both an increase in productivity (quantity of biomass and of compounds of interest in the biomass) and an economically acceptable production cost.
US11560538B2 Beverage maker
A beverage maker may include a fermenter having an opening; a fermentation lid hinged to the fermenter and configured to open and close the opening from above; a hinge shaft connected to the fermentation lid and configured to rotate with the fermentation lid; a rotary gear connected to the hinge shaft; and a gear damper provided at the fermenter and engaged with the rotary gear.
US11560536B2 Aerosol cleaning composition
A nonflammable aerosol cleaning composition is formulated with trans 1,2 dichloroethylene, 1,1,1,2,2,3,4,5,5,5-decafluoropentane, 1,1,1,3,3 pentafluoropropane, HFC-134a, and carbon dioxide. The aerosol cleaning composition is formulated for heavy duty, high pressure, and high output cleaning applications for cleaning aviation parts, such as jet engines located about 10 feet away from a user.
US11560535B2 Organic peroxide dispersions
Evaporation of water from an aqueous dispersion of a solid peroxide such as benzoyl peroxide is retarded by the incorporation of carboxylic acid salt. The carboxylic acid salt renders the aqueous dispersion less susceptible to explosive decomposition when exposed to external triggering events such as impact, heat, friction or contamination, yet does not interfere with the ability to achieve and maintain a stable, small particle size dispersion having desirable viscosity and flow properties.
US11560534B2 Surfactant compositions for improved transparency of DADMAC-acrylamide co-polymers
Liquid laundry detergent compositions including a Diallyldialkylammonium Chloride (DADMAC) Acrylamide co-polymer, and a surfactant system comprising at least one non-ionic surfactant (NI) and at least one linear alkylbenzene sulfonate anionic surfactant (LAS) where the composition has a turbidity of about 50 NTUs or less. The NI is at least about 30 percent by weight of the surfactant system and the LAS is less than about 40 percent by weight of the surfactant system. The surfactant system can also include alcohol ethoxysulfate (AES).
US11560525B2 Diesel fuel composition
A diesel fuel composition containing a renewable diesel component and oxymethylene ethers having molecular structure CH3O—(CH2O)n-CH3 with n=3-5 (OME3-5). A method for producing a diesel fuel composition and use thereof. Use of OME3-5 to decrease particle emission of renewable diesel fuels is further disclosed.
US11560520B2 Multi-stage process and device for treatment heavy marine fuel oil and resultant composition and the removal of detrimental solids
A multi-stage process for reducing the environmental contaminants in an ISO8217 compliant Feedstock Heavy Marine Fuel Oil involving a core desulfurizing process and a Detrimental Solids removal unit as either a pre-treating step or post-treating step to the core process. The Product Heavy Marine Fuel Oil complies with ISO 8217 for residual marine fuel oils and has a sulfur level has a maximum sulfur content (ISO 14596 or ISO 8754) between the range of 0.05 mass % to 1.0 mass and a Detrimental Solids content less than 60 mg/kg. A process plant for conducting the process is also disclosed.
US11560518B2 Polymerizable liquid crystal compound, polymerizable composition, polymer, retardation film, method for producing retardation film, transfer laminate, optical member, method for producing optical member, and display device
A polymerizable liquid crystal compound represented by the following general formula (1): (the symbols in the general formula (1) are as described in the DESCRIPTION.)
US11560516B2 Light emitting device and phosphor
An object of the present invention is to provide an infrared light-emitting phosphor which emits light in a wavelength range where the sensitivity of a detector is high by combination with a semiconductor light-emitting element that emits light in the visible light region, and to provide an infrared light-emitting device using the infrared light-emitting phosphor. The object can be achieved with a light-emitting device including a semiconductor light-emitting element that emits ultraviolet light or visible light and a phosphor that absorbs ultraviolet light or visible light emitted from the semiconductor light-emitting element and emits light in the infrared region, wherein an emission peak wavelength in the infrared region of the phosphor emitting in the infrared region is from 750 to 1,050 nm, and the half width of an emission peak waveform is more than 50 nm.
US11560509B2 Reversible mechanically triggered nanosilica gels
A reversible gel composition including nanosilica and polyethylene oxide, the nanosilica and polyethylene oxide present at concentrations operable to allow for the reversible gel composition to be a flowable liquid at pH greater than about 8 and operable to allow for the reversible gel composition to be a substantially solid gel at pH less than about 8.
US11560508B2 Epoxidized fatty acid methyl ester as primary emulsifier for invert emulsion oil based mud
An invert oil-based mud (OBM) may include an oleaginous continuous phase, an aqueous internal phase, and an emulsifier. The emulsifier may include one or more of the group consisting of epoxidized methyl oleate, epoxidized methyl linoleate, and epoxidized methyl α-linolenate. The invert OBM may contain the emulsifier in an amount of the range of 0.1 to 10 wt. % (weight percent), relative to the total weight of the OBM.
US11560507B2 Method and material for isolating a severe loss zone
A method and drilling fluid additive for reducing severe fluid losses in a well, comprising a combination of granular scrap tire particles and polymer adhesive molded into a cone shape. Once in the severe loss zone, a plurality of LCMs wedge into the formation fractures and seal off the severe loss zone.
US11560503B2 Stable salt hydrate-based thermal energy storage materials
A phase change material composition for latent heat storage is provided. In one embodiment, the phase change material includes a salt hydrate having a melting temperature (Tm) of from 1° C. to 100° C. as determined in accordance with ASTM E793. The phase change material further includes a stabilizing matrix including a polysaccharide selected from the group of a nanocellulose, a sulfonated polysaccharide, a starch, a glycogen, a chitin, and combinations thereof. A composite article including the phase change material composition is also provided.
US11560502B2 Compositions
The present invention provides a composition, such as a refrigerant composition comprising 1,1-difluoroethene (vinylidene fluoride, R-1132a); trifluoromethane (R-23); and one or more compound selected from hexafluoroethane (R-116), ethane (R-170) and carbon dioxide (R-744, CO2).
US11560501B2 Urethane adhesive composition
The present invention is to provide a urethane adhesive composition which exhibits excellent heat-resistant adhesion after storage to resin. The present invention relates to a urethane adhesive composition including: a urethane prepolymer having an isocyanate group; an isocyanurate compound having an isocyanurate ring; a terpene compound having active hydrogen; and a vinyl silane coupling agent represented by Formula (A) below: (where in Formula (A), R1 and R3 each independently represent a monovalent hydrocarbon group, R2 represents a (n+1) valent hydrocarbon group, Vi represents —CH═CH2, m1 is from 1 to 3, m2 is from 1 to 3, m3 is from 0 to 2, m1+m2+m3 is 4, and n is 1 or greater).
US11560499B2 Adhesive composition, adhesive layer and adhesive sheet
The present invention relates to an adhesive composition containing a base polymer and a moisture-curable component, wherein the base polymer contains a polymer having no functional group which reacts with the moisture-curable component, and a water content of the base polymer after storage at 25° C. and 50% RH for 24 hours is 0.1% by weight or less, and wherein the moisture-curable component is contained in an unreacted state, an adhesive layer made from the adhesive composition, and an adhesive sheet including the adhesive layer.
US11560498B2 Process for making pressure-sensitive adhesive and duct tape
A continuous process for making a pressure-sensitive adhesive is disclosed. A mixture comprising natural rubber having a Mooney viscosity of 85 to 100, a tackifier, a filler, and 0.1 to 5 wt. % of an added C12-C24 fatty acid based on the amount of mixture is masticated in a first section of a single- or twin-screw extruder. Mastication of the mixture continues in at least one subsequent extruder section in the presence of additional tackifier. The product is a homogeneous, reduced-viscosity pressure-sensitive adhesive. The minor proportion of added C12-C24 fatty acid aids mastication of the rubber and enables high throughput without addition of peptizers. Duct tapes made from the adhesives display improved adhesion to steel, better adhesion bond strength, and enhanced seven-day clean removability from even difficult substrates such as marble or ceramic tile.
US11560495B2 CMP slurry composition for polishing tungsten pattern wafer and method of polishing tungsten pattern wafer using the same
A CMP slurry composition for polishing a tungsten pattern wafer and a method of polishing a tungsten pattern wafer, the composition including a solvent, the solvent including a polar solvent or a non-polar solvent; an abrasive agent; and an oxidizing agent, wherein the abrasive agent includes silica modified with an amino silane that includes three nitrogen atoms.
US11560493B2 Use of amphiphilic surface modifying additives to improve performance of siloxane-polyurethane fouling-release coatings
The invention relates to curable coating compositions containing at least one surface modifying amphiphilic additive; and at least one siloxane-polyurethane coating composition. The invention also relates to methods of making and using the curable coating compositions of the invention. The invention also relates to objects coated with the curable coating composition of the invention. The invention also relates to methods for reducing or preventing biofouling of a surface exposed to an aqueous environment comprising the steps of coating the surface with the curable coating composition of the invention to form a coated surface, and curing the coating composition on the coated surface. The invention also relates to a marine fouling-release coating containing the curable coating composition of the invention.
US11560489B2 Dispersion liquid of colored resin fine particles for aqueous ink, and aqueous ink composition for writing instruments using same
Provided is a dispersion liquid of colored resin fine particles for an aqueous ink having excellent stability and a sufficient drawn line intensity; an aqueous ink composition for a writing instrument such as felt-tip pens, marking pens, and ballpoint pens using the dispersion liquid of the colored resin fine particle as a colorant; and a writing instrument loaded with the composition. The dispersion liquid of colored resin fine particles for an aqueous ink includes colored resin fine particles dispersed in water, the colored resin fine particles composed of at least a cyclohexyl (meth)acrylate monomer, and a basic dye or an oil-soluble dye, in which the content of the cyclohexyl (meth)acrylate monomer is 30% by mass or more, and the content of the basic dye or the oil-soluble dye is 15% by mass or more based on the total polymer component constituting the colored resin fine particles.
US11560488B2 Ultraviolet curable ink composition, method for manufacturing bezel pattern in display substrate by using same, and bezel pattern manufactured thereby
The present invention relates to an ultraviolet curable ink composition including a colorant, an epoxy monomer, an oxetane monomer, a cationic photopolymerization initiator, and a polymerization inhibitor, wherein the weight ratio of epoxy monomer:oxetane monomer is 1:0.5 to 1:6, to a method for forming a bezel pattern by using the same, to a bezel pattern manufactured thereby, and to a display substrate having the same.
US11560485B2 Surface-treating agent comprising perfluoro(poly)ether group-containing compound
A surface-treating agent including a perfluoro(poly)ether group-containing silane compound and a perfluoro(poly)ether group-containing compound. The perfluoro(poly)ether group-containing compound contains a radical capturing group or a UV absorbing group in the molecule.
US11560481B2 Surface treatment agent and surface treatment method using the same
Provided is a surface treatment agent including an alkoxysilane compound having a cyclic silazane structure represented by the following general formula (1): wherein R1 represents an unsubstituted linear alkyl group having 6 to 20 carbon atoms, R2 represents a substituted or unsubstituted alkylene group having 3 to 6 carbon atoms that may include a heteroatom, R3 and R4 each independently represent a substituted or unsubstituted monovalent hydrocarbon group having 1 to 10 carbon atoms, and n represents an integer of 0 or 1.
US11560480B2 High wet fast disperse dye mixtures of N-[4-(5-fluoro-2,4-dinitro-phenylazo)-phenyl]-amine derivatives and N-[4-(4-nitro-phenylazo)-phenyl]-amine derivatives
The present invention is directed to dye mixtures comprising dyes of formula (1) and dyes of formula (2), the process of the production and the use of the dye mixtures.
US11560475B2 Photocurable resin composition, cured product, and laminate
An object of the present invention is to provide a photocurable resin composition capable of obtaining a cured product having excellent quick curability by irradiation with a low integrated light intensity and flexibility.A photocurable resin composition containing the following components (A) to (E): component (A): a monofunctional urethane (meth)acrylate having a polyether skeleton; component (B): a monofunctional (meth)acrylic monomer having a polyether skeleton and having no urethane skeleton; component (C): a photoradical polymerization initiator; component (D): a polyfunctional (meth)acrylic monomer having 4 or more functionalities; and component (E): a polyester-based plasticizer having no (meth)acryloyl group.
US11560468B2 Thermoformable film
A thermoformable film including a polyethylene composition. The polyethylene composition includes a first polyethylene which is an ethylene copolymer having a weight average molecular weight of from 70,000 to 250,000 and a molecular weight distribution Mw/Mn of <2.3, a second polyethylene which is an ethylene copolymer or homopolymer having a weight average molecular weight of less than 75,000 and a molecular weight distribution Mw/Mn of <2.3, a third polyethylene which is an ethylene copolymer or homopolymer having a weight average molecular weight of less than 75,000 and a molecular weight distribution Mw/Mn of <2.3, and a fourth polyethylene which is an ethylene copolymer or homopolymer having a weight average molecular weight of from 100,000 to 250,000 and a molecular weight distribution Mw/Mn of >2.3, where the first polyethylene has more short chain branching than the second polyethylene or the third polyethylene. The polyethylene composition has a melt flow ratio (I21/I2) of ≤55 and an area Dimensional Thermoformability Index (aDTI) at 105° C. of less than 15.
US11560466B2 Composite material
A composite material and method of producing a composite material for use in fabrication, building and construction is disclosed. A composition as disclosed herein comprises a high proportion of particulate waste material dispersed in a matrix of thermoplastic polymer and wax. A method of producing a composite material comprises melt mixing thermoplastic polymer and wax with a particulate material, thereby dispersing the particulate material in a melt mixture of the composite material.
US11560463B2 Cross-linking agent compound and polymer prepared using the same
The present disclosure relates to a novel cross-linking agent compound and a polymer prepared using the same. Specifically, the present disclosure relates to a cross-linking agent compound having a novel structure and excellent in cross-linking and pyrolysis, and a polymer prepared using the same.
US11560462B1 Functionalized high cis-1,4-polybutadiene
It has been found that carboxylic acid functionalized high cis-1,4-polybutadiene rubber which is comprised of polybutadiene rubber chains having a cis-1,4-microstructure content of at least 90 percent has much better interaction with metal salts of α,β-ethylenically unsaturated carboxylic acids, such as zinc diacrylate or zinc dimethacrylate. This results in such rubber compositions being stiff while still exhibiting a lower level of hysteresis. These characteristics are beneficial when used in manufacturing tire apex compositions, in manufacturing golf ball cores, and in a wide variety of other applications. Such rubber compositions can be used as substitutes for thermoplastic elastomers in many applications.
US11560458B2 Polyamide-based resin expanded beads
Polyamide-based resin expanded beads having a crystallite size of more than 8 nm as measured by X-ray diffraction method are provided.
US11560457B2 MDO thermoresistant heat-shrinkable film
The present invention relates to an MDO heat-shrinkable film of a copolymer polyester having excellent thermal resistance. In particular, the present invention provides a copolymer polyester MDO (machine direction orientation) thermoresistant heat-shrinkable film that consists of a copolymer polyester resin including isosorbide and 1,4-cyclohexanedimethanol at an optimized content ratio as a diol component copolymerized with an acid component including terephthalic acid, and having a number average molecular weight of 18,000 g/mol or more, and can be used for labels, cap seals, direct packaging, etc. of various containers due to the high shrink initiation temperature.
US11560456B2 Single-shaft extruder and use of a single-shaft extruder, and method for altering morphology of a superabsorbent polymer, specifically an SAP polymer gel, using a single-shaft extruder
A single-screw extruder for changing a morphology of superabsorbent polymer gel. The single-screw extruder has an input aperture, a channel, a screw and an output aperture. The screw in the invention has a first pitch value of a pitch of the screw flights along the conveying zone of the channel and, following in conveying direction, has a second pitch value of the pitch of the screw flights along the conveying zone of the channel, where the second pitch value is smaller than the first pitch value.
US11560455B2 Method for rapid gelation of silk fibroin solution under physiological conditions
The invention provides a method for rapid gelation of a silk fibroin solution under physiological conditions. The method comprises steps of: (1) weighing NapFF solid powder into a glass vial and adding ultrapure water; (2) adding a NaOH solution, dissolving and heating for 1-2 min at 70° C. to form a transparent solution; (3) slowly adding a HCl solution and stirring until the pH is 7.2-7.5; (4) adding a silk fibroin solution; (5) adding ultrapure water to set the volume to 200 μL; and (6) standing horizontally, and observing the gelation process by tilting and inverting the glass vial. In the invention a low concentration of silk fibroin solution can be induced to rapidly gelate in a short time. The silk fibroin gel can be degraded by proteolytic hydrolysis in human body, has no toxic side effects, has good biocompatibility, and thus can be used as a good biomaterial.
US11560454B2 Curable composition
A curable composition including a perfluoro(poly)ether group-containing silane compound having two or more Si atoms each bonding to at least one of a hydroxyl and hydrolyzable group, and a perfluoro(poly)ether group represented by: —(OC6F12)a—(OC5F10)b—(OC4F8)c—(OC3X106)d—(OC2F4)e—(OCF2)f—, wherein a, b, c and d are each independently an integer of 0 to 30, e and f are each independently an integer of 1 to 200, the sum of a, b, c, d, e and f is at least 5, the occurrence order of respective repeating units with the subscript a, b, c, d, e or f is not limited, a ratio of e to f is less than 1.0, and each X10 is independently a hydrogen, fluorine or chlorine atom; an organosilicon compound having at least two —O—Rg3(s) each bonding to a Si atom, wherein each Rg3 is independently a hydrogen atom or a monovalent organic group; and a catalyst.
US11560452B2 Monoepoxide-monoamine adducts as wetting agents and dispersants
The invention relates to epoxide-amine adducts obtainable by reaction of one or more primary amines (A) of general formula (I) Q-NH2  (I) with one or more monoepoxides (B) of general formula (II) wherein Q is a radical Rt-[OEt]n[OPr]m[OBu]s-, in which Rt is a radical selected from alkyl radicals having 1 to 6 carbon atoms, OEt is an ethylene oxide radical, OPr is a propylene oxide radical and OBu is a butylene oxide radical, n is a number from 0 to 100, m is a number from 3 to 50 and s is a number from 0 to 20 and n+m+s=3 to 170, R is an organic radical selected from aliphatic radicals having 4 to 24 carbon atoms, aromatic radicals having 6 to 18 carbon atoms and araliphatic radicals having 7 to 34 carbon atoms, and p is 0 or 1, wherein (i) the primary amine(s) (A) and the monoepoxide(s) (B) are reacted in an equivalents ratio (A):(B) of from 1:2 to 1:1.35; and (ii) at least 40 mol % of the radicals R are selected from aromatic radicals having 6 to 18 carbon atoms and araliphatic radicals having 7 to 24 carbon atoms; and optionally subsequent salification and/or quaternization and/or modification of the reaction product. The invention furthermore relates to wetting agents and dispersants comprising or consisting of the epoxide-amine adducts and also to the production of the wetting agents and dispersants and to the use of the epoxide-amine adducts and the wetting agents and dispersants for the production of dispersions. The invention also relates to dispersions and particle formulations comprising the epoxide-amine adducts and wetting agents and dispersants.
US11560451B2 Polymer composition for selective sintering
A polymer composition for the production of shaped objects via selective sintering includes ≥70.0 wt % of poly(ethylene terephthalate), wherein ≥25.0 wt % and ≤90.0 wt % of the poly(ethylene terephthalate has resulted from a selective sintering process as unsintered material. The polymer composition is a powder having a D10 of ≥10 and ≤40 μm, a D50 of ≥75 and ≤100 μm, and a D90 of ≥160 and ≤200 μm. The polymer composition allows for the production of an article having a continuous use temperature of ≥100° C., and results in a low change of molecular weight during exposure to selective sintering powder processing temperatures. Further, the polymer composition allows for a significant reduction of the waste material generated during selective sintering as the unsintered material does not have to be disposed of as waste but may be used again.
US11560444B2 Method of producing block copolymer capable of creating specific structure pattern
A block copolymer including a first block consisting of a polymer having a repeating structure of a structural unit (u1) containing no silicon atom, and a second block consisting of a polymer having a repeating structure of a structural unit (u2) containing a silicon atom, the second block containing a block (b21) consisting of a polymer having a repeating structure of a structural unit (u21) represented by general formula (u2-1) shown below, and the volume ratio of the first block, based on all blocks constituting the block copolymer being 42 to 44 vol %: In which RP211 represents an alkyl group, a halogenated alkyl group, a hydrogen atom, or an organic group having a polar group; and RP212 is a group derived from a compound represented by formula SHRt1, wherein Rt1 represents a hydrocarbon group having 1 to 5 carbon atoms optionally having a substituent.
US11560442B2 Functionalized resin having a polar linker
Polar silane linkers are provided that attach to resins to form silane-functionalized resins. The functionalized resins can be bound to hydroxyl groups on the surface of silica particles to improve the dispersibility of the silica particles in rubber mixtures. Further disclosed are synthetic routes to provide the silane-functionalized resins, as well as various uses and end products that benefit from the unexpected properties of the silane-functionalized resins. Silane-functionalized resins impart remarkable properties on various rubber compositions, such as tires, belts, hoses, brakes, and the like. Automobile tires incorporating the silane-functionalized resins are shown to possess excellent results in balancing the properties of rolling resistance, tire wear, and wet braking performance.
US11560441B2 Method for preparing polyolefin using supported hybrid metallocene catalyst
The present disclosure relates to a method for preparing a polyolefin using a supported hybrid metallocene catalyst. According to the present disclosure, a polyolefin having a narrow molecular weight distribution can be prepared very effectively by introducing a cocatalyst in an optimum content in the presence of a supported hybrid metallocene catalyst containing two or more metallocene compounds having a specific chemical structure. The polyolefin prepared according to the present disclosure exhibits excellent uniformity in chlorine distribution in polyolefin during chlorination, thereby significantly improving elongation of the chlorinated polyolefin, compatibility with PVC and impact reinforcing performance. Thus, it exhibits excellent chemical resistance, weather resistance, flame retardancy, processability and impact strength reinforcing effect, and can be suitably applied as an impact reinforcing agent for PVC pipes and window profiles.
US11560440B2 Aluminoxane-activated metallocene catalysts
Catalyst system, the catalyst system comprising (i) at least one metallocene complex of formula (I) wherein Mt1 is Hf, X is a sigma-donor ligand, R1, R2, R3 are the same or different from each other and can be hydrogen or a saturated linear or branched C1-C10 alkyl, whereby the alkyl group can optionally contain up to 2 heteroatoms belonging to groups 14-16 of the periodic table, or R1 and R2 or R2 and R3 can form a ring having 4 to 6 C-atoms and 1 to 3 double bonds, R4 and R5 are the same or different from each other and can be saturated linear or branched C1-C10 alkyl, C5-C10 aryl, C6-C20 alkylaryl or C6-C20 arylalkyl groups, which can optionally contain up to 2 heteroatoms belonging to groups 14-16 of the periodic table, n can be 1 to 5, Ar is a C6-C20-aryl or -heteroaryl group, which can be unsubstituted or substituted by 1 to 5 linear or branched C1-C10 alkyl group(s), and (ii) an aluminoxane cocatalyst and (iii) optionally an aluminium alkyl compound AI(R7)3, with R7 being a linear or branched C2-C8-alkyl group.
US11560439B2 Hydroxypropyl starch for preparing empty capsules and hydroxypropyl starch-based soft capsules
This invention comprising in hydroxypropyl starch for preparing empty capsules in alimentary and medical use, and hydroxypropyl starch-based soft capsules. This invention takes water as solvent, mix with propylene epoxide and catalyst for reaction, after washing, drying, hydroxypropyl starch is completed. The MS level of substitution of starch is around 2˜5, gelatinization point between 25˜60° C. After the hydroxypropyl starch is gelatinized by heating in water, a hydroxypropyl starch matrix soft capsule can be prepared. The invention consists in introducing hydroxypropyl by modifying the molecular chain of starch to improve the flexibility and hydrophilicity of starch. Therefore, a hydroxypropyl starch matrix soft capsule capable of preparing a flexible and disintegrating property is provided.
US11560438B2 Porous polymeric cellulose prepared via cellulose crosslinking
The invention relates to porous polymeric cellulose prepared via cellulose crosslinking. The porous polymeric cellulose can be incorporated into membranes and/or hydrogels. In preferred embodiments, the membranes and/or hydrogels can provide high dynamic binding capacity at high flow rates. Membranes and/or hydrogels comprising the porous polymeric cellulose are particularly suitable for filtration, separation, and/or functionalization media.
US11560434B2 Formulation for anti-α4β7 antibody
Antibody formulations are described comprising a mixture of an anti-α4β7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.
US11560433B2 Methods of treatment by targeting VCAM1 and MAEA
Antibodies and antibody fragments that inhibit the activity of vascular cell adhesion molecule 1 (VCAM1) and/or macrophage erythroblast attacher (MAEA) are provided, along with formulations and kits comprising these antibodies and antibody fragments and the use of the disclosed compositions, formulations, and kits to treat cancers, sickle cell disease, and Polycythemia Vera.
US11560432B2 Monoclonal antibodies directed to peptide in the context of MHC and methods of making and using monoclonal antibodies
Phycoerythrin (PE) and peptide:MHCII (p:MHCII) reactive monoclonal antibodies; methods to generate monoclonal antibodies including, for example, peptide:MHC (p:MHC) reactive monoclonal antibodies; compositions including monoclonal antibodies; and uses thereof.
US11560431B2 Anti-PD-L1 antibodies and methods of making and using thereof
The application provides the anti-PD-L1 monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
US11560430B2 Anti-PD-1 antibodies and uses thereof
Provided are anti-PD-1 antibodies or fragments thereof. In various example, the antibodies or fragments thereof includes a heavy chain variable region comprising heavy chain complementarity determining regions HCDR1, HCDR2, and HCDR3, and a light chain variable region comprising light chain complementarity determining regions LCDR1, LCDR2, and LCDR3. Methods of using the antibodies or fragments thereof for treating and diagnosing diseases such as cancer, infection or immune disorders are also provided.
US11560428B2 CD33-binding polypeptides and uses thereof
Provided herein are VHH-containing polypeptides that bind CD33. Uses of the VHH-containing polypeptides are also provided.
US11560427B2 Heavy-chain antibodies (VHHs) against claudin 18A2 and use thereof
The present disclosure relates to the field of biology, in particular, to an anti-CLD18A2 VHH. The present disclosure provides an anti-CLD18A2 VHH. A complementarity determining region (CDR) of the anti-CLD18A2 VHH includes CDR1-CDR3 having amino acid sequences as shown below: CDR1 having an amino acid sequence represented by one of SEQ ID NO. 4-11, CDR2 having an amino acid sequence represented by one of SEQ ID NO. 19-26, and CDR3 having an amino acid sequence represented by one of SEQ ID NO.33-39. The anti-CLD18A2 VHH of the present disclosure can specifically bind to the epitope on CLD18A2, and the corresponding fusion protein thereof has good specificity and affinity for CLD18A2, and has a noticeable tumor suppression effect.
US11560425B2 Use of anti-FAM19A5 antibodies for treating cancers
The present disclosure relates to the pharmaceutical use of antagonists (e.g., an antibody or antigen-binding portion thereof) that specifically bind to FAM19A5 to promote a blood vessel normalization and treat a disease (e.g., cancer) in a subject in need thereof, e.g., by promoting a blood vessel normalization.
US11560419B2 Targeting tumor microenvironments with recombinant prokaryotic collagen-like proteins
A recombinant collagen-like protein comprising a binding domain having binding capacity for both extra domain A and extra domain B-containing variants of cellular fibronectin. Cancer may be treated BY administering the recombinant collagen-like protein to a patient.
US11560412B2 Compositions comprising GRIM-19 therapeutics and methods of use
The present invention provides nucleic acids encoding a fusion protein comprising a nucleotide sequence encoding GRIM-19 or a biologically active fragment or derivative thereof and a nucleotide sequence encoding a protein transduction domain. Proteins encoded by the nucleic acids, pharmaceutical compositions and methods of treatment are also provided. The invention also provides viral vectors comprising GRIM-19 or a biologically active fragment or derivative thereof, pharmaceutical compositions and methods of treatment using the same.
US11560408B2 Conjugated virus-like particles and uses thereof as anti-tumor immune redirectors
Disclosed is a new class of conjugated virus-like particles (VLPs). These conjugated VLPs bind a wide variety of tumors and comprise epitopes recognized by a prior T cell immune response already existing in a host. These epitopes are derived from pathogens or previous vaccinations (such as early childhood vaccines). This provokes the body's pre-existing cytotoxic immunity obtained through previous infection or previous childhood vaccination to be redirected to the tumor cells for the elimination of cancer, and form long-term anti-tumor immunity. The described conjugated VLPs are useful for tailoring a broad range of tumors towards a response from existing immunity circumventing the need to identify tumor antigens or generate tumor-specific immune responses. Importantly, the compositions and methods described herein broadens opportunities for treatment for all cancer types in subjects who previously had un-targetable cancers due to various technological and biological limitations of currently available immuno-therapeutic drugs.
US11560407B2 FOXP3-binding peptides and uses thereof
The present invention provides peptides of general formula (I) and salts thereof, wherein: R1 and R2, taken together, form a birradical linker; and R2′ is hydrogen; or, alternatively, R1 is selected from hydrogen, —C(═O)—CH2—NH—C(═O)—(C1-C5)alkyl, and —C(═O)—(C1-C20)alkyl; one of R2 and R2′ is hydrogen and the other is selected from —C(═O)NR3R4, and —C(═O)OH; and R3 and R4 are same or different and are selected from hydrogen and (C1-C10)alkyl.These peptides are highly efficient in binding and inhibiting FoxP3, being efficient in inhibiting and blocking Treg cell functionality, which make them useful in the treatment of cancer.The present invention also provides constructs comprising the peptide of formula (I) as well as combinations comprising the peptide of formula (I), the construct or both.
US11560405B2 Peptides and combination thereof for use in the immunotherapy against cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11560404B2 Crystalline dipeptides useful in the synthesis of elamipretide
Disclosed are crystalline forms of L-Lys(Boc)-Phe-NH2 and Boc-D-Arg-DMT. The crystalline forms may be used in the synthesis of elamipretide.
US11560401B2 Method for preparing oligonucleic acid compound
A method for subjecting a compound [A] having a hydroxyl group or a primary or secondary amino group and a compound [B] having a substituent containing a phosphorus atom to a condensation reaction to prepare a compound [C] represented by the following general formula [C]: wherein the condensation reaction is carried out in a mixed solvent containing a polar solvent and a halogen solvent as a reaction solvent.
US11560398B2 Organic electroluminescent materials and devices
Provided is a process for preparation of a compound of Formula 1 where, ring Y and ring Z are each independently a 5-membered or 6-membered carbocyclic or heterocyclic ring; Z1 and Z2 are each independently C or N; each RY and RZ independently represents mono to the maximum possible number of substitutions, or no substitution; x=1, 2, or 3; y=0, 1, or 2; and x+y=3. Disclosed is a chemical synthesis process that involves contacting a compound of Formula 2 with a compound of Formula 3 in an organic solvent to yield a compound of Formula 1
US11560395B2 Azithromycin derivatives containing a phosphonium ion as anticancer agents
This invention relates to compounds that are useful as cancer therapies. The compounds comprise azithromycin derivatives having a phosphonium cation tethered to the azithromycin macrocycle. The invention also relates to methods of using said compounds and to pharmaceutical formulations comprising said compounds.
US11560383B2 Compound and polymer compound containing the compound
Provided is a compound having higher fluorescence quantum yield and higher optical stability than a conventional FLAP and a polymer compound containing the compound. A: seven or eight-membered ring structure, Y1, Y2, Y3: halogen atom or the like, a1: number of Y1, a2: number of Y2, B: number of Y3, 0≤m and n≤3: when 1≤m≤3, Y1 may be substituted with a structure portion defined by m, when 1≤n≤3, Y2 may be substituted with a structure portion defined by n, and B1, B2: Formulas (2-1) to (2-3). C1, C2, C3: structure containing a cyclic hydrocarbon compound, D1, D2, D3: substructure that inhibits aggregation, E1, E2, E3: polymerizable substructure, Z1: hydrogen atom or the like, c: number of substituent groups Z1, Z2, Z3: hydrogen atom or the like, and may form a ring with C2.
US11560379B2 Octahydro fused azadecalin glucocorticoid receptor modulators
The present invention provides octahydro fused azadecalin compounds and methods of using the compounds as glucocorticoid receptor modulators.
US11560378B2 Treatment of osteoarthritis
Provided are compositions and methods for treating osteoarthritis including intra-articular administration of a compound of Formula (I) including amorphous and polymorph forms thereof.
US11560370B1 5-membered heteroaryl carboxamide compounds for treatment of HBV
The present disclosure provides, in part, 5-membered heteroaryl carboxamide compounds, and pharmaceutical compositions thereof, useful for disruption of HBV core protein assembly, and methods of treating Hepatitis B (HBV) infection.
US11560359B2 Oxopiperazine helix mimetics for control of hypoxia-inducible gene expression
The present invention relates to oxopiperazines that mimic helix αB of the C-terminal transactivation domain of HIF1α. Also disclosed are pharmaceutical compositions containing these oxopiperazines and methods of using these oxopiperazines (e.g., to reduce gene transcription, treat or prevent disorders mediated by interaction of HIF1α with CREB-binding protein and/or p300, reduce or prevent angiogenesis in a tissue, induce apoptosis, and decrease cell survival and/or proliferation).
US11560357B2 Methods of producing pyrazole compounds
The present invention is directed to methods of producing substituted pyrazole based compounds through novel intermediates and unique processes for preparing such intermediates which enables synthesis of final product through commercially viable route of synthesis. The present invention is also directed to novel methods of producing substituted pyrazole based thyroid like compounds, and solid forms of 3-{4-[(7-hydroxy-6-methyl-indan-4-yl)methyl]-3,5-dimethyl-1H-pyrazol-1-yl}-propanoic acid, its pharmaceutical compositions, and methods of preparation thereof.
US11560353B2 Tricyanohexane purification methods
The present disclosure relates generally to processes for recovering tricyanohexane (TCH) via purification of by-product or co-product streams of adiponitrile production. In particular, the present disclosure relates to a process for purifying tricyanohexane (TCH), the process having the steps of (a) separating an adiponitrile process stream comprising adiponitrile and TCH to form a first overhead lights stream comprising low-boiling components and high-boiling components and a first bottoms heavies stream comprising high-boiling components and solid impurities; and (b) separating the first overhead lights stream in a distillation column to form a second overhead lights stream comprising low-boiling components, a second bottoms heavies stream comprising high-boiling components, and a TCH stream comprising TCH and less than 10 wt. % impurities; wherein the distillation column is a low pressure distillation column.
US11560351B2 Methods and compositions incorporating alkyl polyglycoside surfactant for use in oil and/or gas wells
Methods and compositions comprising an emulsion or a microemulsion for use treating an oil and/or gas well are provided. In some embodiments, the emulsion or the microemulsion comprises an aqueous phase, a solvent, a surfactant comprising alkyl polyglycoside, an alcohol, and, optionally, one or more additives.
US11560350B2 Process for producing alkyl methacrylates with improved water and acid management
A process for producing alkyl methacrylates, in particular methyl methacrylate (MMA), includes production of methacrolein (MAL) in a first reaction stage; direct oxidative esterification (DOE) of the methacrolein with an alcohol, preferably methanol, to afford an alkyl methacrylate in a second reaction stage; and workup of the alkyl methacrylate crude product from the second reaction stage. An optimized workup of the reactor output from the oxidative esterification of methacrolein involves minimizing the amount of employed water, the amount of employed acid, and/or the amount of aqueous waste streams, through an optimized recycling of the generated process water streams.
US11560336B2 Method for producing semiconductor production device component, and semiconductor production device component
A first ceramic member and a second ceramic member are joined together at a lower joining temperature while reducing the loss of bond strength. A method for producing a semiconductor production device component includes a step of providing a first ceramic member including an AlN-based material, a step of providing a second ceramic member including an AlN-based material, and a step of joining the first ceramic member and the second ceramic member to each other by thermally pressing the first ceramic member and the second ceramic member to each other via a joint agent including Eu2O3, Gd2O3 and Al2O3 disposed between the first ceramic member and the second ceramic member.
US11560330B2 Patterned glass articles and methods of making the same
A patterned article that includes: an alkali silicate glass substrate comprising a thickness and a primary surface, the substrate having a bulk composition; a patterned region defined by at least a portion of the primary surface; and a compressive stress region that extends from the at least a portion of the primary surface to a first depth within the substrate. The patterned region comprises a surface roughness (Ra) from about 1 nm to about 600 nm and at least one of a plurality of protrusions and a plurality of depressions. Further, each of the compressive stress region and the patterned region comprises a concentration of at least one alkali metal ion that is different than the concentration of the at least one alkali metal ion in the bulk composition.
US11560328B2 Ultra low melting glass frit and fibers
Disclosed herein are methods for forming low melting point glass fibers comprising providing a glass feedstock comprising a low melting point glass and melt-spinning the glass feedstock to produce glass fibers, wherein the glass transition temperature of the glass fibers is less than or equal to about 120% of the glass transition temperature of the glass feedstock. The disclosure also relates to method for forming low melting point glass frit further comprising jet-milling the glass fibers. Low melting point glass frit and fibers produced by the methods described above are also disclosed herein.
US11560327B2 Bubble generator
A bubble generator including a container having a side wall and a top wall defining a cavity. An insert is located within the cavity defining a gas path with a trap portion. The gas path being in communication with an exit in the container. The cavity including an opening receiving a gas accumulating within the cavity, the gas path allowing the accumulating gas to escape through the exit once the accumulating gas reaches a predetermined level proximate the trap portion.
US11560326B2 Fluid treatment system and process
A fluid treatment system is provided. A clarification reactor or chamber, configured for receiving an influent, is provided wherein separated water and separated solids may be formed from the influent while inside and/or outside the reactor. An influent inlet, positioned essentially at the top of the reactor, configured to allow the influent to enter the reactor is provided. A separated water outlet is provided, positioned essentially at the top of the reactor, that is configured to allow the separated water to exit the reactor. A solids discharge is also provided, positioned essentially at the bottom of the reactor, that is configured to allow the separated solids to exit the reactor. A downward angled baffle, positioned inside the reactor, is configured to deflect the separated solids towards the solids discharge.
US11560320B2 Solid electrolyte material and battery
A solid electrolyte material contains Li, M, and X. M is at least one selected from metallic elements, and X is at least one selected from the group consisting of Cl, Br, and I. A plurality of atoms of X form a sublattice having a closest packed structure. An average distance between two adjacent atoms of X among the plurality of atoms of X is 1.8% or more larger than a distance between two adjacent atoms of X in a rock-salt structure composed only of Li and X.
US11560316B2 Process and apparatus for removal of impurities from chlorosilanes
A process for removal of impurities, in particular of dopants, from chlorosilanes which includes the following steps: (a) heating a deposition surface (3); (b) contacting the heated deposition surface (3) with at least one gaseous chlorosilane mixture, the gaseous chlorosilane mixture including at least one chlorosilane and at least one impurity, in particular at least one dopant; (c) at least partially removing the impurity, in particular the dopant, by forming polycrystalline silicon depositions on the deposition surface (3), the polycrystalline silicon depositions being enriched with the impurity, in particular with the dopant; (d) discharging the purified gaseous chlorosilane mixture; (e) contacting the heated deposition surface (3) with an etching gas to return the polycrystalline silicon depositions and the impurity, in particular the dopant, into the gas phase to form a gaseous etching gas mixture; and (f) discharging the gaseous etching gas mixture.
US11560315B2 Graphene structure having graphene bubbles and preparation method for the same
The present invention provides a graphene structure having graphene bubbles and a preparation method for the same. The preparation method comprises: providing a substrate; forming a hydrogen terminated layer on a top surface of the substrate and a graphene layer disposed on a top surface of the hydrogen terminated layer; and placing a probe on the graphene layer and applying a preset voltage to the probe, to excite a part of the hydrogen terminated layer at a position corresponding to the probe to convert into hydrogen, the hydrogen causing the graphene layer at a position corresponding to the hydrogen to bulge, so as to form a graphene bubble enveloping the hydrogen.
US11560314B2 System and method for synthesis of graphene quantum dots
The embodiments herein provide a system and a method for the synthesis of Graphene Quantum Dots (GQDs) for use in applications like nano-electronics, photonics, bio-imaging, energy storage, quantum computing, etc. Cu substrate is placed inside the CVD tube, and the CVD Chamber is sealed. The process parameters for CVD process are set up. Precursor gases injected inside the tube are dissociate to form carbon dimers and trimmers. Upon cooling semi-cyrstalline carbon film deposits inside the CVD tube. Oxidizing gas mixture is injected to convert amorphous C in semi-cyrstalline carbon film to CO2/CO. Graphene Quantum Dots (GQDs) so formed are carried with the gas flow and deposited at the cooler end of tube. The scrapper assembly is inserted in the CVD Tube and the reagent is sprayed inside the tube to disperse these GQDs in the reagent. This dispersion is pumped out of the CVD Chamber.
US11560311B2 Apparatus for thermally cracking a hydrocarbon gas
A nanoparticle or agglomerate which contains connected multi-walled spherical fullerenes coated in layers of graphite. In different embodiments, the nanoparticles and agglomerates have different combinations of: a high mass fraction compared to other carbon allotropes present, a low concentration of defects, a low concentration of elemental impurities, a high Brunauer, Emmett and Teller (BET) specific surface area, and/or a high electrical conductivity. Methods are provided to produce the nanoparticles and agglomerates at a high production rate without using catalysts.
US11560310B1 Method for producing a calcium phosphate salt
Methods are disclosed for producing a calcium phosphate salt comprising reacting fluorosilicic acid (FSA) with water and a calcium phosphate source to produce phosphoric acid, calcium fluoride, and silicon dioxide; removing residual solids; performing a first stage precipitation wherein the phosphoric acid generated previously is reacted with a calcium source and water to remove residual fluoride; and performing a second stage precipitation wherein the phosphoric acid generated previously is reacted with a calcium source and water to isolate the product calcium phosphate salt, having a low level of impurities.
US11560308B2 Method and plant for generation of synthesis gas
Method and plant for generating a synthesis gas which consists mainly of carbon monoxide and hydrogen and has been freed of acid gases, proceeding from a hydrocarbonaceous fuel, and air and steam, wherein low-temperature fractionation separates air into an oxygen stream, a tail gas stream and a nitrogen stream, wherein the tail gas stream and the nitrogen stream are at ambient temperature and the nitrogen stream is at elevated pressure, wherein the hydrocarbonaceous fuel, having been mixed with the oxygen stream and steam at elevated temperature and elevated pressure, is converted to a synthesis gas by a method known to those skilled in the art, and wherein acid gas is subsequently separated therefrom by low-temperature absorption in an absorption column, wherein the nitrogen stream generated in the fractionation of air is passed through and simultaneously cooled in an expansion turbine and then used to cool either the absorbent or the coolant circulating in the coolant circuit of the compression refrigeration plant.
US11560305B1 Microfluidic microchips by 3D printing
Function fabrication in a microfluidic device manufactured with a custom 3D printer. The functions may include, for example, transporting or routing fluid, fluid mixing through flow and/or diffusion, blocking fluid (valve), pumping fluid, providing chemical reaction regions, providing analyte capture regions, and providing analyte separation regions. The fluid may be a liquid or a gas.
US11560303B2 MEMS device with a diaphragm having a net compressive stress
An implementation of a MEMS device includes a constrained diaphragm comprising a surface, the diaphragm having a net compressive stress; and a backplate comprising a surface facing the surface of the diaphragm, the surface of the backplate having a center, and a post extending from the surface of the backplate, wherein the post is located at or near a center of the surface and limits a maximum deflection of the diaphragm.
US11560302B2 Micromechanical pressure sensor with two cavities and diaphragms and corresponding production method
In micromechanical pressure sensor device and a corresponding production method, the micromechanical pressure sensor device is provided with a first diaphragm; an adjacent first cavity; a first deformation detection device situated in and/or on the first diaphragm for detecting a deformation of the first diaphragm as a consequence of an applied external pressure change and as a consequence of an internal mechanical deformation of the pressure sensor device; a second diaphragm; an adjacent second cavity; and a second deformation detection device situated in and/or on the second diaphragm for detecting a deformation of the second diaphragm as a consequence of the internal mechanical deformation of the pressure sensor device, where the second diaphragm is developed in such a way that it is not deformable as a consequence of the external pressure change.
US11560293B2 Tower crane with a detection of a rotating part autorotation or oscillation state in an out of service configuration
A tower crane includes a tower on which a rotating portion is pivotally mounted and configurable between a service configuration in which the rotating portion can be rotatably driven by a motorized orientation system, and an out of service configuration in which the rotating portion is rotatably released to be able to be oriented in the direction of the wind. A control/command unit activates a monitoring mode in the out of service configuration to detect, depending on variations in the angle of orientation or the angular speed of the rotating portion, if the rotating portion is in one of the following movement states: an autorotation state corresponding to a rotary movement of the rotating portion in a given direction over at least one complete turn; or an oscillation state corresponding to a back and forth movement of the rotating portion about the orientation axis.
US11560292B2 Measurement target top-surface estimation method, guide information display device, and crane
To estimate the top surface of a measurement target on the basis of a data point group that corresponds to the top surface of a measurement target and is obtained using a laser scanner. This top surface estimation method for hoisting loads and by acquiring, using the laser scanner, data point groups in a hoisting load region which includes a hoisting load and an object from above the hoisting load and the object, dividing the hoisting load region into layers which constitute a plurality of groups which have a prescribed thickness in the vertical direction, and allocating the acquired data point groups to the plurality of layer groups, and estimating the top surfaces of the hoisting load and the object in each layer group on the basis of the data point groups allocated to the plurality of layer groups.
US11560290B2 Carriage and a sliding support apparatus for a stairlift
A carriage (1) for a stairlift is configured for sliding along a support guide (2). The carriage (1) comprises a concave shaped frame (101), defining a seat (S) for housing at least a part of said guide (2); at least one upper roller (102), mounted on an upper portion of said frame (101) to be rotatably engageable resting on an upper surface of a head portion (201) of the guide (2); a rolling member (103), mounted on a lower portion of the frame (101) to be rotatably engageable with a lower surface of a base portion (203) of the guide (2); and first and second lower rollers (104a, 104b), mounted on the frame (101) in the proximity of the rolling member (103) in such a way as to be engaged or can be engaged in rolling movement respectively on a first lateral surface (203a) and a second lateral surface (203b) of the base portion (203) of the guide (2).
US11560289B2 Inspection and maintenance system for elevators
An elevator inspection and maintenance system, the system including a mechatronic body movable via remote or automatic operation, an inspection and maintenance head installed on the mechatronic body, where the inspection and maintenance head is fitted with a sensor or a manipulation tool to perform an inspection or a maintenance operation on at least one component of an elevator system remotely or automatically.
US11560281B2 Device for receiving and holding a surface element roll, in particular a deep-drawing film roll and packaging machine for packing packaging goods in surface element packages
A packaging machine for packaging goods in film packages, equipped with a device for receiving and holding a surface element roll, so as to process it in a packaging machine by unrolling the surface element and introducing the surface element into the packaging machine, comprising an axle to be incorporated into the surface element roll on its rotational axis of symmetry, wherein the axle is received in a swivel receiver, and the axle for unrolling the surface element is held with the swivel receiver in a roughly vertical alignment.
US11560280B2 Medium conveying apparatus for determining conveyance abnormality based on determination result of floating and skew of medium
A medium conveying apparatus includes a floating sensor located on an upstream side of a first roller in the medium conveying direction to detect a floating of the medium placed on a medium tray, a skew sensor located on a downstream side of a second roller in the medium conveying direction to detect a skew of the medium conveyed by the second roller, and a processor to determine whether the floating of the medium has occurred based on an output signal from the floating sensor, determine whether the skew of the medium has occurred based on an output signal from the skew sensor, and determine that a conveyance abnormality of the medium has occurred when the processor determines that the floating of the medium has occurred and the processor determines that the skew of the medium has occurred.
US11560273B2 Vehicle conveyor system and surface system for a vehicle conveyor
In an aspect, a conveyor system is provided for a vehicle having wheels. The conveyor system includes a conveyor having an inlet end positioned to receive a vehicle to be conveyed, and an exit end positioned for exiting of the vehicle off of the conveyor, and a surface positioned proximate to at least one of the inlet end and the exit end. The surface is positioned to support at least one of the wheels while at least another of the wheels is supported on the conveyor. The surface has surface properties selected such that a coefficient of friction between the surface and tire rubber is below a selected threshold so as to permit sliding of the at least one of the wheels on the surface while the at least another of the wheels is supported on the conveyor.
US11560272B2 System and method for picking items
A system and method for picking items from storage containers located in stacks within a grid-based storage system are described. The system can include a movable structural member, movable from a first position to a second position such that when in the second position it is possible for an operative to access at least one row of storage containers such that items can be manually picked therefrom.
US11560264B1 Separable extraction tab accessible blister card package
A disposable package is configured to promote recycling of its component parts. A thermoformed thermoplastic blister has a product bubble which extends from a peripheral flange to extend through an opening in a front card. The front card is affixed to a back card to close the product bubble and so as not to adhere to the blister flange. An extraction tab extends from the peripheral flange and is accessible on two opposed sides for gripping by a user to engage and remove the blister from the front card and the back card.
US11560254B2 Container with interior and exterior graphics
A container is formed from a blank that has a first side and a second side. The first side can have one or more graphics. The container can include a base portion forming an enclosure and first and second overlap panels that collectively form a cover panel that can enclose the enclosure. Methods of constructing the container include forming the cover panel by securing the first and second overlap panels together.
US11560252B2 Folding carton
A foldable carton is provided. The carton includes a bottom panel, a front panel, a rear panel, end panels, each foldably connected to the edges of the bottom panel. The carton further includes front end flap panels connected to the lateral ends of the front panel and rear end flap panels connected to the lateral ends of the rear panel. Each front end flap panel includes a connecting end section and a triangular fold flap connected to the connected end section. The triangular fold flap is connected to a side edge of the adjacent end panel by a hinged fold line. The connecting end section is secured to the front panel in an overlying arrangement and the triangular fold flap is configured to about the hinged fold line to allow the front panel to freely move between a fully upright position and a partially upright position.
US11560250B2 Lightweight plastic container and preform
A plastic container is provided that includes a hollow body portion including a lower supporting base portion; a sidewall portion extending upwardly from the base portion; and a neck portion extending upwardly from the sidewall portion. The neck portion includes a support flange having an upper and lower surface, at least one thread, and a dispensing opening at the top of the neck portion. In embodiments, a closure may be provided to form an assembly. In embodiments, the container may be comprised of PET, the weight of the neck portion from the lower surface of the support flange to a top of the dispensing opening may be 3.0 grams or less, and/or the vertical distance from the top of the dispensing opening to the lower surface of the support flange may be 0.580 inches or less. A preform and method for making a container are also disclosed.
US11560245B2 Strapping device having a pivotable rocker
Various embodiments of the present disclosure provide a mobile strapping device for strapping packaged products using a loop of wrapping strap. The strapping device includes a tensioning device for applying tension to the strap and a connecting device for connecting two overlapping portions of the strap. The tensioning device includes a rotatable tensioning wheel and a tensioning plate. The tensioning wheel is supported by a rocker that is pivotable to change a distance separating the tensioning wheel and the tensioning plate. The mobile strapping device includes a motor that is operably connectable to the rocker or the tensioning wheel such that the motor causes pivoting of the rocker or rotation of the tensioning wheel when operating in a first direction of rotation. In various embodiments, gearing, including a plurality of planetary gear sets, is used to operatively connect the motor to the rocker and the tensioning wheel.
US11560243B2 Spacecraft multifunction connecting mechanisms including interchangeable port opening docking mechanisms, and associated systems and methods
A representative spacecraft system includes a connecting device, which in turn includes a housing having a common port opening, a first connecting element carried by the housing and positioned to connect with a corresponding first spacecraft connecting structure having a first configuration, and a second connecting element carried by the housing and positioned to connect with a corresponding second spacecraft connecting structure having a second configuration different than the first configuration. At least one of the first and second connecting elements is moveable relative to the other between an operational position and a non-operational position, and each of the first and second connecting elements, when connected to the corresponding first or second spacecraft connecting structure, is positioned to allow transport through the common port opening.
US11560240B2 Aircraft area having a textile display, aircraft passenger seat having a textile display, and aircraft including an aircraft area
An aircraft area having a textile display, aircraft passenger seat having a textile display, and aircraft including an aircraft area. An aircraft area includes an interior component, a textile display on the interior component and including at least one textile fiber capable of changing a color at at least one section of the textile fiber, and a controller operatively coupled to the textile display and configured to change color of the at least one section of the textile fiber, such that the textile display displays information. An aircraft passenger seat includes a back rest, seat pan, and textile display integrated into a seat cover covering the backrest and/or the seat pan. The textile display includes at least one textile fiber capable of changing a color at at least one section of the textile fiber. An aircraft may include one or more aircraft areas and/or one or more aircraft passenger seats.
US11560237B2 Method for assisting a single-engine rotorcraft during an engine failure
An assistance method for assisting a pilot of a single-engined rotary-wing aircraft during a flight phase in autorotation, the aircraft including a hybrid power plant provided with a main engine, with an electric machine, with a main gearbox, and with an electrical energy storage device. The aircraft also includes a main rotor driven by the hybrid power plant. In the method, during a flight, operation of the main engine is monitored in order to detect a failure, in particular by means of a drop in power on the main rotor, then, when a failure of the main engine is detected, the electric machine is controlled to deliver auxiliary power We to the main rotor, making it possible to assist a pilot of the aircraft in performing the flight phase in autorotation following the failure.
US11560234B2 Lightweight high power density fault-tolerant fuel cell system, method and apparatus for clean fuel electric aircraft
A lightweight, high power density, fault-tolerant fuel cell system, method, and apparatus for full-scale clean fuel electric-powered aircraft having a fuel cell module including a plurality of fuel cells working together to process gaseous oxygen from air compressed by turbochargers, superchargers, blowers or local oxygen supply and gaseous hydrogen from liquid hydrogen transformed by heat exchangers, with an electrical circuit configured to collect electrons from the plurality of hydrogen fuel cells to supply voltage and current to motor controllers commanded by autopilot control units configured to select and control an amount and distribution of electrical voltage and torque or current for each of the plurality of motor and propeller assemblies, wherein electrons returning from the electrical circuit combine with oxygen in the compressed air to form oxygen ions, then the protons combine with oxygen ions to form H2O molecules and heat.
US11560231B2 Aircraft seating assemblies
A seating assembly may employ one or more of: a seat stagger, a seat overlap, and a seat angling to offer significant width and comfort gains and reduce the negative impact of width and leg room gains on seating density. With one seat of a pair staggered forward with respect to the other seat each may then be moved laterally and overlap (as seen from the front). The seating positions may be further improved by angling each seat away from their center arm rest area, reducing the encroaching effect of the overlap by pointing the passenger away from the overlap, reducing the visual impact of the staggered seating by pointing the passenger away from the nearest seat ahead, and improving leg room by directing the passenger's legs forward at an angle.
US11560227B2 Unmanned aerial vehicle
A vertical take-off and landing (“VTOL”) unmanned aerial vehicle (“UAV”) system and a method of controlling the same, wherein such method controls the stability and maneuverability of the VTOL UAV by manipulating the speeds of the propellers at each rotor. The VTOL UAV includes a body with three extending arms, wherein each of such arms is aligned and fixed at a certain angle from a central axis passing through the body. Each extending arm is equipped with a rotor with propellers. The rotors are sufficient to control the yaw of the UAV, and there is no need for coaxial rotors or an extra servo-motor in order to control the yaw of the UAV, thus reducing the cost and the weight of the UAV.
US11560222B2 Bonded skins for ducted-rotor aircraft
A duct for a ducted-rotor aircraft may include an internal structure and an aerodynamic exterior skin that is adhesively bonded to the internal structure. The skin may include a leading-edge portion disposed at an inlet of the duct and an inner portion disposed along an interior of the duct. The inner portion of the skin may be bonded to the internal structure with a first bondline of adhesive and the leading-edge portion of the skin may be bonded to the inner portion of the skin with a second bondline of adhesive. One or both of the first and second bondlines of adhesive may be of non-uniform thickness to take up tolerance stackups between the inner portion of the skin, the leading-edge portion of the skin, and the internal structure.
US11560221B2 Rotor deployment mechanism for electric vertical take-off and landing aircraft
An aerial vehicle adapted for vertical takeoff and landing using a set of wing mounted thrust producing elements for takeoff and landing. An aerial vehicle which is adapted to vertical takeoff with the rotors in a rotated, take-off attitude then transitions to a horizontal flight path, with the rotors rotated to a typical horizontal configuration. The aerial vehicle uses different configurations of its wing mounted rotors and propellers to reduce drag in all flight modes. The aerial vehicle uses deployment mechanisms to deploy rotor assemblies up and away from their stowed configuration locations.
US11560216B2 System and method for braking flying objects
A system for slowing down the speed of flying objects by applying electrodynamic and aerodynamic braking forces. The system is comprised of plurality of stubs, where each stub is made of dielectric material surrounded by metal foil and another metal foil is inserted in the middle of the stub, where the outer metal foil and the inner metal foil are isolated from each other, so that they form a capacitor. Each stub is stored in a barrel before being used. When activated, the stubs are stretched from the barrel as a tail behind the flying object. The area of the stub generates aerodynamic drag. The stub capacitor is charged by a generator so that free electrons are present in the outer metal layer of the stub. The electric field produced by these charges interacts with ions in the atmosphere.
US11560212B2 System for operating an aircraft door
Systems and methods for operating an aircraft door including an airstair are disclosed. In one embodiment, the system includes a hinge configured to pivotally couple a lower portion of the door to a fuselage of an aircraft, a lift mechanism and an interlock. The lift mechanism causes a movement of the door relative to the hinge between a lowered position and a lifted position. The interlock is configurable between: a locked configuration where the movement of the door relative to the hinge is prevented; and an unlocked configuration where the movement of the door relative to the hinge is permitted.
US11560211B2 Fuselage component for an aircraft, method for producing a fuselage component, and aircraft
A fuselage component for an aircraft, including a shell part composed of a fiber composite material and a stiffening structure which is connected to an inner surface of the shell part and has shaped parts composed of a fiber composite material, wherein the shaped parts each have a flat base section which extends along the inner surface of the shell part, and a step-shaped profile edge which extends in an encircling manner around the base section. The shaped parts are arranged in the form of parquetry with overlapping profile edges. As a result, the overlapping profile edges form stiffening profiles intersecting at an intersection. Furthermore, an aircraft which has at least one such fuselage component and a method for producing a fuselage component are described.
US11560209B2 Drive source switching system for marine propulsion device including multiple drive sources, and method of switching drive sources of marine propulsion device
A drive source switching system for a marine propulsion device includes a first drive source, a second drive source, a propeller shaft, a first driving member, a second driving member, a first driven member, and a second driven member that are movable in an axial direction of the propeller shaft, and a controller. The first driven member transmits a drive force generated by the first drive source to the propeller shaft when engaged with the first driving member. The second driven member transmits a drive force generated by the second drive source to the propeller shaft when engaged with the second driving member. When the controller moves the first driven member that is not engaged with the first driving member toward the first driving member, the controller moves the first driven member back when the first driven member fails to be engaged with the first driving member.
US11560203B2 Surge damping systems and processes for using same
Surge damping systems and processes for using same. In some embodiments, a system for mooring a vessel can include a mooring support structure that can include a base structure and a turntable disposed on the base structure. A vessel support structure can be disposed on the vessel. At least one extension arm can be suspended from the vessel support structure. A ballast tank can be connected to the extension arm. A uni-directional passive surge damping system can be disposed on the vessel and can include an elongated tension member connected to the ballast tank that can be configured to dampen a movement of the ballast tank by applying a tension thereto. A yoke can extend from and can be connected at a first end to the ballast tank and can include a yoke head disposed on a second end thereof that can be configured to connect to the turntable.
US11560199B2 Gearshifting system comprising a linear actuator
A gear shifting system derailleur having a derailleur integrable with devices having a positionable chain, belt and/or a plurality of sprockets. The derailleur includes, a frame, a linear actuator having a housing, two bracket links and a damping element. The linear actuator includes a linearly positionable arm. The bracket links and a damping element are positioned and adapted to apply a biased force against the linearly positionable arm. The damping element is coupled with both the chain pulley and the bracket links, wherein the damping element positions the chain pulley within the derailleur as driven by the bracket links. Wireless and/or wired communications and control modules and pathways are provided to enable user control of the linearly positionable arm. The derailleur may be attached to or comprised within a vehicle, such as a bicycle, a tricycle or a vehicle with more wheels.
US11560196B2 Rake device for a three wheel motorcycle
A method of modifying the rake angle on a motorcycle having a double wishbone front suspension. The motorcycle has a tubular steering housing connected to a non-telescoping fork assembly by a straight body steering stem. The method includes the step of replacing the straight body steering stem with a canted body steering stem. The canted body steering stem includes (i) a primary section having a steering axis corresponding to a steering axis of the motorcycle; and (ii) a secondary section having a cant axis which varies from the steering axis by between 1° and 16°.
US11560194B2 Solar powered electric vehicle system and method
A solar-powered vehicle that includes a body having opposing sides and defining a cavity; two or more wheels; a first and second solar panel assembly respectively disposed on the opposing sides of the body; one or more electric motor disposed within the cavity of the body between the first and second solar panel assemblies, the one or more electric motors configured to rotate at least one of the two or more wheels; and one or more electric battery disposed within the cavity of the body between the first and second solar panel assemblies, the one or more electric batteries configured to power the one or more electric motors and to be charged by electric current generated by the first and second solar panel assemblies.
US11560193B2 User configurable trailer
Methods, systems, and apparatus, including computer programs encoded on computer storage media, coordinate dynamic adjustments of a trailer based in part on a user profile associated with a user physically present at the trailer and an activity profile associated with an activity selected to be performed at the trailer. A dynamic adjustment may modify a tilt of a lower surface of the trailer. A dynamic adjustment may modify a dimension(s) of the trailer based in part on a detected object(s). Various dynamic adjustments may occur concurrently, individually and/or sequentially. The trailer may be a moveable trailer for temporary attachment with a vehicle.
US11560191B2 Traction devices for elastomeric tracks, and related methods
A traction device for an elastomeric track comprises a first bracket comprising a first portion comprising a tapered surface and a second portion configured to be removably coupled to the first portion to define a U-shaped channel configured to receive at least a portion of an elastomeric track, a first chain coupled to the first bracket at a first end of the first chain, a second bracket coupled to a second end of first chain opposite the first bracket, and a plate coupled to the first chain between the first bracket and the second bracket, the plate configured to substantially prevent the first chain from entering the recesses of the elastomeric track. Related traction devices and methods of attaching a traction device to an elastomeric track are also disclosed.
US11560189B2 Track elements for forming a continuous over tyre track with strength enhancement structure
The invention discloses a track element (80) for forming a continuous over tyre track (100), includes a generally C-shaped rigid member (10) having a base portion (10a) extending transversely to the track (100), a tapered side guide member (10b) on each end of the base portion (10a), and at least one inter-engaging connector member (10c) on each side of the base portion (10a); wherein the rigid member (10) is encased in a coating of elastomeric material (20).
US11560182B2 Lock unit for tailgate synchronizer
A latch system for a vehicle includes a synchronizer and a lock unit. The synchronizer is configured to block and allow release of a number of latches of the vehicle such that some latches are blocked from being released if other latches are already released. The lock unit is configured to block selectively the release of the number of latches.
US11560176B2 Driver assistance apparatus and method thereof
A driver assistance apparatus includes an external camera disposed at a vehicle so as to have an outer field of view of the vehicle, configured to obtain image data on the outer field of view of the vehicle; an internal camera disposed inside the vehicle to grasp a drivers gaze on board the vehicle, configured to obtain the drivers gaze data; and a controller including at least one processor configured to process the image data and the gaze data. The controller may be configured to grasp the driver's gaze based on the gaze data, and based on a determination that the driver is in a careless condition, to control at least one of a control timing of a steering device and a lateral distance limit value for operating the steering device to be changed.
US11560175B2 Operator action positioning module for lane assistance function
A blending steering control method includes estimating a handwheel pressure applied by an operator to a handwheel and receiving a handwheel torque input indicating a torque value applied by the operator to the handwheel. The method also includes receiving a target handwheel angle indicating a target handwheel angle of an electronic power steering system configured to control a corresponding vehicle along a defined path. The method also includes generating a scaled operator intent value based on the estimated handwheel pressure and the handwheel torque and generating an output torque value based on the target handwheel angle and scaled operator intent value. The method also includes selectively controlling vehicle trajectory based on the output torque value.
US11560173B2 Method and control arrangement for controlling vehicle freewheel with engine off and power steering
A method (300) and control arrangement (210) for controlling a vehicle (100) to freewheel with engine off. The vehicle (100) has an engine (260) for propelling the vehicle (100) and a hydraulic power steering system (400). The hydraulic power steering system (400) comprises a primary power steering pump (270a) arranged to be driven by the engine (260) and a secondary power steering pump (270b). The method (300) includes: determining (301) when to start freewheeling the vehicle (100) with its engine off; and prior to starting the freewheeling of the vehicle (100) with engine off, determining (302) to start the secondary power steering pump (270b).
US11560171B2 Method for operating a steering device, and steering device
A method operates a steering device which comprises at least one electric motor that can be operated with an increased torque lying between a nominal torque of the electric motor and a maximum torque of the electric motor over an entire basic setting range. In at least one operating state, a threshold torque of the electric motor is at least temporarily limited to a reduced torque, in particular in comparison to the maximum torque, at least depending on at least one temperature characteristic variable.
US11560164B2 Mobile unit control system and mobile unit control method
A mobile unit control system includes an acquisition unit configured to acquire operation information on transportation located around the traveling area of a mobile unit that a user gets on and off while the mobile unit is traveling and a setting unit configured to set the traveling route or the traveling speed of the mobile unit based on the operation information on transportation.
US11560161B2 Railway vehicle, coupler, and coupler body thereof
A railway vehicle, a coupler, and a coupler body thereof. The coupler body comprises an upper traction platform, a lower traction platform, a lock chamber, and a pin hole. A traction surface of an upper traction platform and/or a lower traction platform is divided into a contact area and a yielding area along the direction approaching the lock chamber, an extension face of the end of the contact area close to the lock chamber is an M2 face, and the yielding area is positioned at the side of the M2 face close to the pin hole. The yielding area is positioned on the side of the contact area next to the lock chamber and there is a gap and no contact between the yielding area and a traction platform of a coupler knuckle.
US11560158B2 Robot and method for controlling the same
A robot according to an embodiment of the present disclosure includes an authentication interface for authenticating a user's boarding of the robot using authentication information of the user, a position detector for detecting a position of the robot in a space, a processor for identifying a first section corresponding to the detected position among at least one section in the space, recognizing at least one driving mode for the first section among a plurality of driving modes with different driving speeds, setting one of the recognized at least one driving mode as a driving mode for the first section based on the authentication information, and controlling driving of the robot based on the set driving mode, and a display for outputting information on the set driving mode.
US11560157B2 Remotely operated automatic driving vehicle with in-vehicle emergency stop feature
A driving control device receives power supply from an accessory battery to operate, controls automatic driving, and outputs a control signal. A steering ECU, a power ECU and a brake ECU instruct a steering mechanism, a PCU and a brake to operate based on the control signal, respectively. An emergency stop switch is operated by an operator. In a case where the emergency stop switch is operated, an interface processing device cuts off a switch to stop the power supply, shuts down the driving control device, and outputs a control signal that causes the steering mechanism, the PCU and the brake to perform an emergency stop operation.
US11560156B2 Vehicle control interface, vehicle system, and automated-driving platform
A vehicle control interface includes a control unit configured to: connect between a vehicle platform including a first computer that performs travel control of a vehicle and an automated-driving platform including a second computer that performs automated-driving control of the vehicle and acquire a first control command containing an instruction for the vehicle platform from the second computer; convert the first control command to a second control command for the first computer; and send the second control command to the first computer. The control unit is configured to send, to the second computer, a specifiable range of a physical quantity that is specified by the second computer via the first control command.
US11560151B2 Vehicle control system
A vehicle control system includes a recording device configured to record vehicle information in files. The recording device includes: an event information receiving unit configured to receive information about prescribed events; a tag providing unit configured to provide protection tags to the files, the protection tags being of different types according to magnitude of the events; and an overwriting setting unit configured to prohibit overwriting of the files provided with the protection tags of a same type in a case where the number of the files provided with the protection tags of the same type is within a prescribed upper limit number, and to permit the overwriting of the files provided with the protection tags of the same type in a case where the number of the files provided with the protection tags of the same type exceeds the upper limit number.
US11560149B2 Control apparatus
A control apparatus is provided with a recovery control unit that issues an instruction saying that when there exists a process whose starting condition is an execution state of a process in which an abnormality has been detected, all of processes including the process whose starting condition is the execution state of the process in which the abnormality has been detected should temporarily be stopped and saying that after the process in which the abnormality had been detected has restarted, execution of the processes that have temporarily been stopped should be resumed, and a process execution management unit that restarts the process in which the abnormality has been detected and resumes the processes that have temporarily been stopped, in response to the instruction from the recovery control unit.
US11560148B2 Integrated control apparatus for in-wheel system vehicle
An integrated control apparatus for in-wheel system vehicle is provided. The apparatus includes a shift button for a shift control and a dial for a steering control which are assembled integrally to each other to form one integrated component. The apparatus provides a driver with vehicle information through an operation of the dial when the steering control is not performed, and eliminates a risk of accidents occurring due to a control error by configuring a shift control manner and a steering control manner to be different from each other.
US11560147B2 Information providing device, movable body, and method of providing information
An information providing device includes an external environment recognition unit that recognizes an external environmental situation of a movable body, an information providing control unit that provides a notification of recommended stopping information based on a current indication of traffic signals recognized by the external environment recognition unit, and a determination unit which determines, in the case that a first intersection and a second intersection are positioned in a travel direction of the movable body, whether or not a degree of proximity of the first intersection and the second intersection satisfies a predetermined condition. In the case it is determined by the determination unit that the predetermined condition is satisfied, the information providing control unit prevents the recommended stopping information based on a current indication of the traffic signal belonging to the second intersection from being provided.
US11560145B2 Travel path recognition apparatus and travel path recognition method
An object is to provide technology capable of appropriately recognizing a travel path. A travel path recognition apparatus includes a travel path recognizer. The travel path recognizer calculates a traveling distance traveled by a vehicle from acquisition time of lane marking information to current time based on a vehicle speed of vehicle behavior. Then, the travel path recognizer determines whether or not the lane marking information is information within a usable period in which the lane marking information is usable to recognize the travel path based on a predetermined lane marking acquirable distance and the traveling distance. The predetermined lane marking acquirable distance is a distance in front of a position of the vehicle, and is a distance in which a lane marking of the lane marking information is acquirable.
US11560143B2 Vehicular autonomous parking system using short range communication protocols
A vehicular communication system includes a wireless communication sensor at a vehicle equipped with the vehicular communication system for receiving wireless communication data from remote wireless communication devices. A global positioning system is operable to determine a geographical location of the vehicle. An electronic control unit (ECU) includes electronic circuitry and associated software that includes a processor for processing wireless communication data received by the wireless communication sensor and position information determined by the global positioning system. The ECU, responsive at least in part to determination that position information determined by the global positioning system is compromised, determines, via processing the received wireless communication data, distances to a plurality of the remote wireless communication devices. The ECU, responsive to determining the distances to the plurality of the remote wireless communication devices, determines a position of the vehicle relative to the plurality of the remote wireless communication devices.
US11560139B2 Pulse start method for an internal combustion engine of a hybrid vehicle
A hybrid drive device has an internal combustion engine, a clutch transmission which has at least one free partial transmission and a partial transmission connected to an electric machine with in each case a clutch, and at least one electric machine. In order to start the internal combustion engine, pulse energy is provided from an inertia of the clutch associated with the free partial transmission and/or a rotation in the free partial transmission.
US11560137B2 Powertrain system
A control device of a powertrain system executes a control input determination processing and a system control processing. The control input determination processing includes a co-state variable determination processing to update a co-state variable p of an optimization problem for each time step and a control input calculation processing. The co-state variable determination processing includes an initial value determination processing that determines, as an initial value of the co-state variable p, the sum of a base value of the initial value and an external charge/discharge correction value. The base value is a final value or an average value of the co-state variable p during the last control time period. The external charge/discharge correction value is determined based on an external charge/discharge amount obtained by subtracting a SOC at the end of the last control time period from the SOC at the start of the current control time period.
US11560136B2 Control device
A control device for a hybrid vehicle is provided with a driving plan preparing part preparing a driving plan setting one or more via-points on a projected route from a starting point to a destination to divide the projected route into a plurality of driving routes and divide the driving routes further into pluralities of driving sections and setting which driving mode of an EV mode or HV mode to drive over in each driving section and with a driving mode switching part switching the driving modes according to a driving plan. The driving plan preparing part is configured to be able to prepare a driving plan setting the driving modes of all driving sections in at least one driving route to the EV mode.
US11560129B2 Method for operation of a brake back-up system of a motor vehicle
The invention concerns a method for operating a brake back-up system (8) of a motor vehicle (2), with the steps: (S100) Reading in operating data (BD) of the motor vehicle (2), (S200) Evaluating the read-in operating data (BD) to identify malfunctions of a braking system of the motor vehicle (2), and (S300) Providing at least one actuation signal (AS, AS′) to influence components of a drive train of the motor vehicle (2).
US11560126B2 Method for emergency response to a transportation vehicle tire pressure loss and transportation vehicle
A method for an emergency response in the event of a loss of tire pressure of a transportation vehicle including detecting a tire pressure at a wheel of the transportation vehicle and detecting an angle of inclination on an axle of the transportation vehicle associated with the wheel, A transportation vehicle for autonomous driving.
US11560121B2 Distance measurement device and distance measurement method
A first device includes: a first reference signal source; a first transmitting/receiving unit which transmits two or more first carrier signals and receives two or more second carrier signals using an output of the first reference signal source; and a calculating unit. A second device includes: a second reference signal source configured to be operated independently from the first reference signal source; and a second transmitting/receiving unit configured to transmit two or more second carrier signals and receive two or more first carrier signals using an output of the second reference signal source. A frequency group of two or more first carrier signals and a frequency group of two or more second carrier signals differ from each other. The calculating unit calculates a distance between the first device and the second device based on a phase detection result obtained by receiving the first and second carrier signals.
US11560119B1 Pregnancy seat belt or safety harness
A pregnancy seat belt that secures an expectant mother and her unborn baby due to the absence of a lap belt traversing the expectant mother's abdomen. The expectant mother is secured instead by a center belt and/or thigh-belts that secure the mother at her thighs and avoid traverse of her abdomen.
US11560118B2 Drive assembly for driving a vehicle flap
A drive assembly, in particular for driving a flap (5), includes a hinge assembly (2), comprising a first hinge part (3) connectable to a vehicle body and a second hinge part (4) connectable to a vehicle flap (5), a joint assembly (7) comprising at least a first joint part (8) hingedly connecting said first hinge part (3) with said second hinge part (4) and a first actuator (10) for driving the second hinge part (4) to move between an opened and a closed position during a normal operation. The first actuator (10) has a first end (10a) coupleable to a vehicle body pivotally about a first pivot axis (P1) and a second end (10b). The drive assembly also includes a bearing element connected (16) to the first actuator (10) and a coupling assembly (14) for coupling the first actuator (10) to the hinge assembly (2), comprising a first coupling part (15) having a first end (15a) and a second end (15b). The first end (15a) of the first coupling part (15) is coupled to one of the second hinge part (4) and first joint part (8) pivotally about a second pivot axis (P2). The bearing element (16) of the first actuator (10) is coupled to the second end (15b) of the first coupling part (15) pivotally about a third pivot axis (P3) spaced apart from the second pivot axis (P2). The drive assembly provides a possibility to move a vehicle flap drivingly between a closed and an opened position and further provides a reliable pedestrian protection function.
US11560117B2 Vehicle occupant restraint system having an airbag module and method for assembling an airbag
A vehicle occupant restraint system comprises an airbag module (12) including an inflator (18) and a frontally acting airbag (16), wherein the airbag (16) includes an inflator-side inflation end (46) as well as a first free end (56) located in the inflated state of the airbag (16) within a vehicle interior. In a first period during deployment of the airbag (16), the first free end (56) is still connected via a tether (74) to the airbag module (12), wherein the tether (74) becomes detached upon reaching a predetermined tensile force. When folding the airbag (16), the non-inflated airbag (16) is spread so that a second free end (58) is maximally distant from the inflation end (46) and a first outer wall portion is stretched in the longitudinal direction of the airbag (16), and the first free end (56) is located in the vicinity of the inflation end (46) and a second outer wall portion is stretched in the longitudinal direction of the airbag (16), wherein a third outer wall portion of the airbag (16) is folded back onto itself at least in a portion. The two lateral areas of the spread airbag (16) are folded toward the center, and subsequently the airbag (16) is rolled up from the second free end (58).
US11560112B2 Vehicle seat device
A vehicle seat device includes: a detection unit that detects a side collision in a vehicle; a seat that is provided in a vehicle cabin so that the seat can be located at a center portion of the vehicle cabin in a vehicle width direction and that can face at least one of a front side and a rear side in a vehicle front-rear direction; a restraint portion that is provided on a seat side portion and that is movable between a retracted position in which the restraint portion does not face a seated occupant seated in the vehicle width direction, and a facing position in which the restraint portion faces the occupant in the vehicle width direction; and a movement control unit that positions the restraint portion at the facing position when the seat is located at the center portion and the detection unit detects the side collision.
US11560109B2 Airbag apparatus
An airbag apparatus to be applied to a vehicle includes airbags, a pre-crash determiner, an airbag deployment controller, and an airbag contraction controller. The airbags are configured to be deployed forward of a vehicle body front of the vehicle, and are disposed in a vehicle width direction. The pre-crash determiner is configured to establish a pre-crash determination when a probability of a collision with an object is a predetermined value or higher. The airbag deployment controller is configured to deploy the airbags in response to establishment of the pre-crash determination. The airbag contraction controller is configured to control contraction of the airbags individually, and perform side airbag contraction control by contracting one of the airbags that is on one side in the vehicle width direction and in a region where the collision with the object is occurring, and keeping deployed another one or more of the airbags in the region.
US11560107B2 Impact-absorbing structure
An impact-absorbing structure includes: a bumper face; a bumper beam; and an impact-absorbing member interposed to be compressively deformed between the exterior member and the movable-body-side rigid member. The movable-body-side rigid member, in an up-and-down direction of the movable-body-side rigid member, includes: a plurality of recesses recessed toward the movable body; and a protrusion protruding forward the movable body to be formed between the plurality of recesses. The plurality of recesses each have a vertical width gradually tapering toward the movable body, and the impact-absorbing member is fitted into at least two of the plurality of recesses.
US11560104B2 Spring clip
A spring clip for coupling a panel to a vehicle structure having at least one mounting member, includes a base portion, with upper and lower surface, configured to couplingly engage with the mounting member, and a body portion, having a central axis extending away from the lower surface of the base portion and having a first planar wall member and a second planar wall member, opposingly spaced apart from the first wall member with regards to the central axis, each one of the planar wall members extending away from the lower surface towards and joiningly converging into a distal end on the central axis. The body portion further includes at least a first pair of opposing retention elements, each one disposed on and extending laterally outwards from a respective one of the planar wall members, configured to fixingly engage when inserted into an orifice of the panel, during use.
US11560098B2 Vehicle roof system and method of controlling same
A vehicle roof system and a method of controlling the vehicle roof system are provided. The vehicle roof system includes an opening-closing module that is provided on a roof of a vehicle and a loading module that is provided on the top of the opening-closing module. A locking mechanism is also provided within the loading module. The opening-closing module is slid in one direction or in the opposite direction to open or close the roof. The loading module has a loading space that is separated from an indoor space in the vehicle, with the opening-closing module disposed in between. The locking mechanism supports a weight of a load when in operation for locking and no longer supports the weight of the load when in operation for unlocking.
US11560097B2 Support system for a removable vehicle canopy
In a first aspect, the present invention relates to a support system for mounting a load to a removable vehicle canopy on a vehicle, comprising a pair of support frames configured to be installed on opposing internal side walls of the removable vehicle canopy, a pair of support feet configured to be installed on an internal surface of the removable vehicle canopy, and a plurality of mounting elements on an external surface of the canopy and arranged for mounting the load thereto, each of the support frames and support feet having one of the plurality of mounting elements affixed thereto by a mechanical fastener extending through a hole in the canopy, wherein the support system is configured to be installable onto the removable vehicle canopy while the canopy is mounted to the vehicle, such that when the canopy having the support system installed is mounted to the vehicle, the support system substantially distributes the mounted load into the vehicle and substantially inhibits distribution into or through the canopy. The invention further includes a second aspect being a method of installation of an embodiment of the first aspect.
US11560092B2 Vehicular vision system
A vehicular vision system includes a camera disposed at a vehicle, at least one non-vision sensor disposed at the vehicle, and a display system of the vehicle that displays video images for viewing by the driver of the vehicle. Image data captured by the camera and sensor data sensed by the non-vision sensor are provided to a control of the vehicle. Responsive at least in part to processing at the control of image data captured by the camera, video images are displayed by a video display screen of the display system. The vehicular vision system determines an augmented reality overlay and the video display screen also displays the augmented reality overlay. The displayed augmented reality overlay pertains to at least one accessory of the equipped vehicle and/or is responsive at least in part to a driving condition of the equipped vehicle.
US11560088B2 Wheel or tire with illuminable feature
Tire or wheel for use on a vehicle, machine, equipment, toy or the like. The tire or wheel has an illuminable feature including at least one optical fiber.
US11560084B2 Vehicle
When a first driver setting mode indicates an “OFF mode” or an “AUTO mode,” a VP accepts a light operation mode request from an ADK. When an operation is performed by a user, the VP changes an operation mode of a headlight in accordance with the operation by the user. When the operation by the user has not been performed, the VP changes the operation mode of the headlight in accordance with the light operation mode request.
US11560083B2 Autonomous headlamp encapsulated with camera and artificial intelligence processor to adjust illumination
Provided herein is a headlamp assembly comprising a housing that encloses: a sensor that acquires data associated with a surrounding environment; a light source that illuminates a field of view comprising a portion of the surrounding environment; and one or more processors that analyze the acquired data and determine a direction, field of view, power, or an intensity of the illumination of the portion based on the analyzed data.
US11560081B2 Front grill with LED module lighting system
Disclosed herein is a vehicle accessory grill comprising a plurality of edge protrusions, a front surface, a rear surface, a plurality of air apertures, and a plurality of lighting apertures. The grill also comprises a lighting system which may comprise a control module and a plurality of lamps. The plurality of lamps may include a plurality of high beam lamps, a plurality of low beam lamps, a plurality of daytime running lamps, and a plurality of turn lamps.
US11560077B2 Support structure, apparatus and method
A support structure for supporting the user of a mobility device or the like, the support structure comprising a fluid flow channel, the fluid flow channel comprising a fluid inlet and a fluid outlet, wherein at least part of the fluid flow channel is tapered, the at least part tapered fluid flow channel comprising a first end and a second end, the first end of the at least part tapered fluid flow channel being located proximal to the fluid inlet and the second end of the at least part tapered fluid flow channel being located distal to the fluid inlet, and wherein the width of the second end of the at least part tapered fluid flow channel is greater than the width of the first end of the at least part tapered fluid flow channel.
US11560071B2 Device for improving the accessibility of the storage space below vehicle seats
A device for improving the accessibility to the space below a vehicle seat (1) and thus its use as a storage space. The device enables the position of the seat (1) or a seat guide (2) with the seat (1) arranged above to be moved in the direction of the front of the vehicle (7) such that accessibility to the stowage space which is in the form of a receiving container (6) or a support is ensured.
US11560070B2 Device having push button switch for operating power seat of vehicle
A device having push button switches for operating a power seat of a vehicle, includes a switch module in which a plurality of push button type switches for an input operation to drive a power seat to a target position and in a target direction are modularized; a plurality of touch sensors embedded in the plurality of push button type switches and configured to indicate operating directions of the power seat; a main controller configured to determine an operating direction of the power seat according to a sensing signal from a touch sensor in which a touch sensing operation is performed among the plurality of touch sensors; and a display configured to display the operating direction of the power seat determined by the main controller as one arrow and visually guide a user.
US11560066B2 High voltage battery bypass for electric vehicle fleet
A system for powering an electric vehicle (EV) includes a battery, a power distribution module, and a battery bypass module. The power distribution module receives power from a charging station, draws power from the battery in a discharging mode, distributes power from the charging station to the battery in a charging mode, and distributes power to a plurality of subsystems of the EV. The battery bypass module is coupled to the battery and the power distribution module. When the battery bypass module is engaged in a charging bypass mode, power distributed by the power distribution module bypasses the battery and is distributed to at least a subset of the plurality of subsystems of the EV.
US11560065B2 Method and apparatus to manage electric vehicle charging stations and parking spaces
Electric vehicle charging stations are in high demand, as the number of electric vehicles on the road is rising. A novel method and apparatus invention effectively manages the charging station parking space by detecting and taking action on ineligible vehicles that are parked for a long time without charging so that others can use the spot. The invention employs multiple ultrasonic sensors to see if the parking space is occupied or not, and a current sensor to see if the parked vehicle is drawing current through the charging cable or not. Depending on those two outcomes, the invention adopts a monitoring process using audio-visual alarm devices and a communication device to notify parking authorities to take action if the parked vehicle is deemed ineligible. The invention also explains the calibration process of ultrasonic sensors for detecting the presence or absence of a vehicle in the parking space.
US11560063B2 Charging connector control system and method
A charging connector control system may include a charging control unit of a charging equipment for supplying a control signal for charging; and a vehicle control unit for changing a sensing control signal to a normal control signal by executing a variable resistor control according to whether the sensing control signal, which is generated by sensing the control signal transmitted through a charging connector for connecting the charging equipment and a vehicle, is normal.
US11560057B2 Device and method for displaying content
An electronic device attachable to a vehicle, according to various embodiments of the present invention, comprises: a communication interface; a memory for storing instructions; and at least one processor connected to the communication interface and the memory, wherein the at least one processor can be configured so as to execute the stored instructions in order to: acquire, from another device embedded in the vehicle, information on a plurality of objects located within a designated distance from the vehicle; identify, among the plurality of objects, a designated object located within a designated distance from the vehicle; generate configuration information of at least one piece of content to be displayed through a head-up display (HUD), on the basis of a state of the designated object; and display, through the HUD, content for guiding the operation of the vehicle, on the basis of the generated configuration information.
US11560056B2 Ballast weight management system for a work vehicle
A work vehicle includes: a chassis; a first axle carried by the chassis; a pair of first wheels rotatably coupled to the first axle; a first weight sensor associated with the first axle and configured to output a first weight signal; a second axle carried by the chassis; a pair of second wheels rotatably coupled to the second axle; a second weight sensor associated with the second axle and configured to output a second weight signal; and a controller operatively coupled to the first and second weight sensors. The controller is configured to: receive the first and second weight signals; determine a weight distribution of the work vehicle based on the received first and second weight signals; analyze the determined weight distribution to determine at least one recommended operating parameter; and output a recommendation signal based on the at least one recommended operating parameter.
US11560054B2 Method for operating a drive train of a vehicle
A method for operating a drive-train of a vehicle, such as a municipal or agricultural utility vehicle, having at least one drive machine, a vehicle transmission with at least two gears, at least one drive axle and at least one auxiliary power take-off. The method includes controlling or regulating a supply of normal power from the drive machine as a function of a normal torque characteristic. Depending on the operating situation, supplying additional power to the at least one drive axle and/or to the at least one auxiliary power take-off. The supplied additional power is controlled or regulated as a function of operating situation dependent torque characteristics which are called up as a function of the selected gear at the time.
US11560053B2 Electric vehicle comprising a vertical electric propulsion motor and method of making and using the same
An electric vehicle comprises a vehicle chassis extending along a longitudinal axis and a rotatable vehicle drive axle disposed along a transverse axis and having opposed ends that are configured for attachment to a pair of opposed drive wheels. The electric vehicle also comprises a selectively movable electric propulsion motor comprising a rotatable motor shaft rotatable about a motor axis, the electric propulsion motor configured to be mounted within the vehicle chassis and operatively coupled to the rotatable vehicle drive axle and opposed drive wheels, the motor axis configured to be oriented in a substantially vertical direction.
US11560052B2 Multipurpose vehicle
A multipurpose vehicle includes an engine, a travel transmission device, a continuously variable transmission device, and a spacer housing capable of becoming attached to and detached from the engine, the continuously variable transmission device, and the travel transmission device. The spacer housing contains an engine output shaft, a transmission device input shaft of the continuously variable transmission device, a first connecting portion connecting the engine output shaft with the transmission device input shaft in an interlocking manner, a transmission device output shaft of the continuously variable transmission device, a transmission input shaft of the travel transmission device, and a second connecting portion connecting the transmission device output shaft with the transmission input shaft in an interlocking manner.
US11560051B2 Fault-tolerant fuel isolation from engine firebay
Fuel isolation systems, apparatuses and methods are described. In some embodiments, a system comprises a fuel tank, a fuel pump, an engine, a firewall, a fuel line from the fuel tank to the engine, a connector coupled inline with the fuel line on a cold side of the fuel line, a valve coupled to the connector, an air feed line coupled to an air source and to the valve. In the event of an engine fire condition, a control unit outputs signaling to turn off the fuel pump and operate the valve to introduce air from the air source into the fuel line. The introduced air provides a siphon break in the fuel line such that the only fuel that can pass the firewall is the remaining fuel in the fuel line downstream of the connector and the introduced air.
US11560048B2 Active air flap device for vehicle
An active air flap device for a vehicle may include: a housing part mounted in a bumper cover part; one or more flap parts rotatably mounted in the housing part, and exposed to the outside through a hole formed in the bumper cover part to form the same skin line as the bumper cover part; a link part connected to the flap part; a loader part mounted in the link part; and a driving part configured to rotate the loader part.
US11560046B1 School bus emergency egress system
An emergency egress system for a multi-passenger vehicle such as a school bus (10) includes a housing (30) that operatively supports a ramp (34) in movable connection therewith. Opening an emergency exit door (18) of the bus causes a housing door (24) to open and the ramp to move outwardly from a retracted position toward an extended position. Opening the emergency exit door also causes the suspension of the bus to be automatically lowered to place the emergency exit opening (16) closer to the ground (166).
US11560045B2 Composite liftgate
A composite liftgate system with an inner panel construction having a strengthening channel structure. Structural composite reinforcements are bonded to the inner panel where additional strength is needed to meet predetermined performance requirements. Where the extra structure is needed, no steel or a minimum amounts of steel is used and the structural reinforcements are bonded in place using adhesive prior to application of additional fasteners.
US11560044B2 Ventilation device for an automobile passenger compartment
A ventilation device for an automobile passenger compartment is provided. The ventilation device includes a control mechanism, including a drive shaft and a first and a second driven shaft for controlling a first ventilation flap. The first and second driven shafts are connected to the drive shaft by way of a coupling element, wherein the coupling element is designed as a differential.
US11560042B2 Heat pump refrigerant loop arrangements
A heat pump includes a refrigerant loop. The refrigerant loop includes a compressor, a first condenser, a vapor generator having a first region and a second region, a first expansion valve, a second expansion valve, and a first evaporator. A branching point is positioned between the first condenser and the vapor generator. The branching point diverts a portion of a first heat exchange fluid circulating through the refrigerant loop to the vapor generator. The first expansion valve is positioned between the branching point and the vapor generator. An outlet of the vapor generator is coupled to a mid-pressure inlet port of the compressor.
US11560039B2 Vehicular heater
A vehicular heater includes a heat medium circuit connected to a heater core that heats vent air via heat exchange with a heat medium. The heat medium circuit includes a first flow path connected to the heater core through a power unit, and a second flow path arranged in parallel with the first flow path and connected to the heater core through a heat source different from the power unit. A controller adjusts a first flow rate of the heat medium in the first flow path to be larger than a second flow rate of the heat medium in the second flow path when the power unit is operating.
US11560037B2 Vehicle interior environment control
A computer-implemented process for controlling a vehicle interior includes detecting a previously defined situation that relates to an undesirable environmental condition of the vehicle interior, and assessing both a risk level and an urgency level, based on a vehicle sensor input. The process also includes generating a vehicle command based upon the detected previously defined situation, the assessed risk level, and assessed urgency level, and executing the generated vehicle command to control at least one of an engine, a window, and a heating, ventilation and air conditioning (HVAC) unit to modify an environmental condition of the vehicle interior.
US11560035B2 Method of operating an adjustable roll stabilizer
A method for operating an adjustable roll stabilizer for a motor vehicle. The adjustable roll stabilizer has an actuator which relative to a rotational axis can be rotated through a system angle in order to twist two stabilizer sections connected to it about the rotational axis relative to one another. The stabilizer sections are each coupled to a respective wheel suspension at a radial distance away from the rotational axis, and, starting from a target angle to be set at the actuator and having regard to the actual system angle and other parameters of the adjustable roll stabilizer and/or the motor vehicle equipped with it, a position-rotational speed regulator determines a target motor torque on the basis of which a motor of the actuator is controlled, so that having regard to the target angle and the actual system angle, the target motor torque is checked for plausibility.
US11560026B2 System and method for hitch angle estimation
A system for estimating a hitch angle includes a control module with memory for storing programmatic control logic, a processor for executing the control logic, and one or more input/output (I/O) ports. Wheel speed sensors on a trailer communicate with the processor via the I/O ports. A trailering application defines a portion of the control logic and has at least first, and second control logics. The first control logic estimates the hitch angle from a first term, a second term and physical parameters of the vehicle and trailer. The second control logic provides the estimated hitch angle to one or more of a driver and to on-board control systems of the vehicle and trailer.
US11560024B1 System, apparatus and method for adjusting air pressure in a tire
A pressure adjustment device for adjusting air pressure within a tire of a vehicle is disclosed. The device includes a housing formed of a cap and a base and including a piston, a spring and an air valve, wherein the cap includes an air inlet and the base includes an air outlet that is in fluid communication with the neck, wherein the piston moves proximally to compress the spring in response to a presence of a centrifugal force due to the vehicle traveling at least at a predetermined speed, where the proximal movement of the piston activates the air valve thereby enabling fluid to flow into the housing, and where the spring is configured to decompress when the centrifugal force decreases thereby deactivating the air valve and compressing the fluid within the housing distally out the air outlet toward the tire.
US11560023B2 Tire comprising a conductive cord
Tire (1) having sidewalls (2), a substantially electrically insulating crown block (7) and a substantially insulating tread (8), the tire (1) also having at least one conductive peg (21) that is oriented in the radial direction and positioned under the tread (8) of the tire so as to create an electrically conductive path between the ground and a rim on which the tire is able to be mounted.
US11560022B2 Rotatable smart wheel systems and methods
This application relates generally to sensor systems and, more particularly, relates to systems and methods for management of smart wheel sensors that collect actionable sensor data from a rotatable component of a vehicle's wheel. In certain embodiments, a system includes a vehicle body; a rotatable component configured to rotate relative to the vehicle body; an energy harvesting component disposed along a circumference of the rotatable component, wherein the energy harvesting component is configured to generate electric power based on a force to the rotatable component; a sensor configured to produce sensor data by using the electric power while disposed on the rotatable component; and at least one processor disposed within the vehicle body, the at least one processor configured to perform an action within the vehicle body based on a parameter value meeting a threshold value, wherein the parameter value is based on the sensor data.
US11560021B2 Stud of a tire
Disclosed is a tire stud comprising a stainless steel body with a flange and a blind hole and further comprising a spike installed in said hole, wherein the cross-sectional shape of the hole is different from the cross-sectional shape of the spike at least at one of: the opening, the lower surface of the spike, and a depth between the opening lower surface of the spike; whereby only protrusions of the spike are attached to the side wall of the hole with friction joints where the cross-sectional shape of the hole is different from the cross-sectional shape of the spike.
US11560019B2 Tire
A tire has a tread portion including a first land portion including first and second circumferential edges and and a tread surface. On the first land portion, curved grooves are provided in a tire circumferential direction. Each curved groove extends from a first end on the first circumferential edge side, terminates at a second end within the first land portion, and includes first and second curved portions and on the first end and second end sides, respectively. The first curved portion is an arc curve with a radius of curvature having a center on the first circumferential edge side of the curved groove. The second curved portion is an arc curve with a radius of curvature having a center on the second circumferential edge side of the curved groove.
US11560006B2 Thermal transfer sheet
A thermal transfer sheet is provided, which allows for forming an image favorable to any transfer objects having a poor smoothness or a high smoothness. The thermal transfer sheet according to the present invention includes a substrate, and a transfer layer. The transfer layer includes a release layer, a colorant layer and an adhesive layer. The release layer includes a polyethylene glycol having a number average molecular weight Mn in a range of 8000 or more to 23000 or less, and the colorant layer includes a colorant and a vinyl chloride-vinyl acetate copolymer.
US11560005B2 Counterfeit detection using machine readable indicia
This disclosure relates to counterfeit detection and deterrence using advanced signal processing technology including steganographic embedding and digital watermarking. Digital watermark can be used on consumer products, labels, logos, hang tags, stickers and other objects to provide counterfeit detection mechanisms.
US11560002B2 Adjusting tension of a substrate
An example method comprises operating a drive unit to advance a substrate in a substrate advance direction toward a printing station. At the printing station, a first line is printed onto the substrate. A drive unit is instructed to advance the substrate in the substrate advance direction by a target amount, and a second line is printed onto the substrate. The distance between the first and second lines in a direction perpendicular to the substrate advance direction is calculated and, based on the calculated difference, a tension of the substrate is modified.
US11560000B2 Printing apparatus, control method, and non-transitory computer-readable storage medium
A printing apparatus includes a conveyance unit including a pair of rotation members that nip a roll sheet, and configured to convey the sheet by rotation of the pair of rotation members, a printing unit, and a control unit configured to, upon executing a new print job, cause the conveyance unit to perform a preparatory operation in which the sheet is conveyed in a forward direction and then conveyed in a reverse direction and stopped. If a predetermined condition is met after completion of a previous print job, the control unit causes the conveyance unit to perform the preparatory operation, and if the predetermined condition is not met after completion of a previous print job, the control unit does not cause the conveyance unit to perform the preparatory operation.
US11559997B2 Heating device, dryer, liquid discharge apparatus, and printer
A heating device includes a conveyor configured to convey a sheet, the sheet having a first surface on which a liquid is applied and a second surface contacting the conveyor, a first heater facing the first surface opposite to the second surface of the sheet, the first heater configured to heat the sheet, and a second heater configured to heat the conveyor.
US11559994B2 Inkjet printing apparatus and method of controlling inkjet printing apparatus
An inkjet printing apparatus is provided with a tank that stores ink, a print head that performs print operation by ejecting ink supplied from the tank, a circulation unit that establishes a circulating state to circulate ink in a circulation path if print operation is performed and establishes a stopped state to stop circulation of ink if print operation is terminated, and a deaeration unit that performs deaeration operation to deaerate ink inside the circulation path. The apparatus includes an estimation unit that estimates a dissolved gas amount in ink inside the circulation path based on dissolved gas amounts increased in the circulating state and in the stopped state, respectively, and a control unit that causes the deaeration unit to execute deaeration operation after completion of print operation if the dissolved gas amount estimated by the estimation unit exceeds a predetermined threshold.
US11559991B2 Method of capping printheads arranged along curved media path
A method of capping printheads positioned along a curved media path having an apex. The method includes the steps of: providing a first printhead upstream of the apex and a corresponding first capper downstream of the first printhead; providing a second printhead downstream of the apex and a corresponding second capper upstream of the second printhead; moving the first capper towards the first printhead and capping the first printhead; and moving the second capper towards the second printhead and capping the second printhead. The first and second cappers are moved in opposite directions away from the apex for capping the first and second printheads.
US11559990B2 Liquid discharge head, discharge device, liquid discharge apparatus, and bonded substrate
A liquid discharge head is configured to discharge a liquid, and the liquid discharge head includes an actuator substrate and a holding substrate bonded to the actuator substrate. The actuator substrate includes a pressure generator, and a wiring electrode configured to electrically connect the pressure generator and an exterior of the liquid discharge head. The holding substrate includes an opening configured to expose the wiring electrode to the exterior of the liquid discharge head, and a detection surface adjacent to the opening, the detection surface having a higher reflectance than a surface of the wiring electrode of the actuator substrate.
US11559989B2 Liquid ejecting head and liquid ejecting apparatus
The individual flow path includes a nozzle communicating with an outside, a first flow path, in the middle of which the nozzle is disposed and which extends in a first direction that is an in-plane direction of a nozzle surface of the nozzle plate in which the nozzle opens, a second flow path coupled to the first flow path and extending in a second direction other than the first direction, a third flow path coupled to the second flow path and extending in the third direction other than the second direction, and a pressure chamber which is disposed in the third flow path and in which a pressure change is induced by the energy generating element. A cross-sectional area of the first flow path is smaller than a cross-sectional area of the second flow path.
US11559988B2 Compensation method and device for nozzle in inkjet printer and inkjet printer
A compensation method includes determining position information of an abnormal nozzle of an inkjet head; acquiring printing parameters, determining first data corresponding to the abnormal nozzle, and based on the position information of the abnormal nozzle and the printing parameters, determining position information of a compensation nozzle for compensating the first data corresponding to the abnormal nozzle; and based on the printing parameters, acquiring second data of the compensation nozzle in a normal printing state which includes ink out data and ink holding data, determining an address of the ink holding data, and generating compensation data by writing the first data into the address of the ink holding data. A compensation device includes: an abnormal nozzle position determination module; a compensation nozzle position determination module; and a compensation data generation module. An inkjet printer includes: a controlling unit, an inkjet head unit, and a nozzle compensation unit.
US11559987B2 Fluidic die with surface condition monitoring
One example provides a fluidic die including a nozzle layer disposed on a substrate, the nozzle layer having an upper surface opposite the substrate and including a plurality of nozzles formed therein, each nozzle including a fluid chamber and a nozzle orifice extending through the nozzle layer from the upper surface to the fluid chamber. A conductive trace is exposed to the upper surface of the nozzle layer and extends proximate to a portion of the nozzle orifices, an impedance of the conductive trace indicative of a surface condition of the upper surface of the nozzle layer.
US11559981B2 Heat press, especially knee lever-transfer press
The present disclosure relates to a heat press, especially knee lever-transfer press with at least one socket, with at least one base plate and with at least one heatable counter plate pivotable towards the base plate, wherein the knee lever-transfer press further has a control unit, by which the knee lever-transfer press is controllable in an open-loop manner and/or closed-loop manner and wherein the control unit constitutes a first modular unit of the knee lever-transfer press and wherein the socket constitutes at least one second modular unit, and the base plate and the counter plate constitute at least one third modular unit and wherein at least the first modular unit and the second modular unit and/or the third modular unit are separable from each other and/or are formed to be replaceable for functional comparable modular units.
US11559980B2 Dryer
The present invention relates to a dryer for treating a moving printing web in a rotary printing press with gas, having a nozzle body. The dryer according to the invention is characterized in that the nozzle body has at least one opening for the exit of heated gas and has at least one opening for recirculating the cooled gas.
US11559979B2 Method of printing objects in a pad printing machine in two stages
A pad printing machine (1) to print an object (8) in at least two stages, said machine comprising at least one printing pad (6) to print said object and at least two printing plate zones (10) within each of which a printing plate (14) may be moved into the desired position, the pad printing machine furthermore comprising an image recorder (44) generating an image of at least a partial area of at least one printing plate zone (10), and a comparator (46) to compare the image generated by said recorder (44) with reference data.
US11559976B2 Gravure printing units and method for adjusting and/or modifying an ink transfer in a gravure printing method
A gravure printing unit, which is usable for printing on a substrate, according to a gravure printing method, includes a forme cylinder which comprises, on its circumference, an image-forming pattern of recesses, and an inking unit, by the use of which the pattern of recesses provided on the forme cylinder is inked. The forme cylinder can be partially inked from an inking device via a first inking unit cylinder which has recesses in the region of its outer cylindrical surface that correspond to recesses on the forme cylinder, and via a second inking unit cylinder, which cooperates with the first inking unit cylinder and which comprises ink-transferring elements or raised areas on its circumference. For controlling the transfer of ink, the first inking unit cylinder having the recesses, is configured as being temperature controllable or has a temperature control device in the ink unit supply. Alternatively, a printing pressure between inking units cylinders can be varied during operation. The invention also relates to a method for adjusting or modifying a transfer of ink and for operating the gravure printing unit.
US11559975B1 Dissolvable adhesive liner label and methods of making and using same
A duplex label. The duplex label has a first face ply having a printable upper side and a lower side, and a second face ply having an upper side and a printable lower side. A layer of patterned adhesive is situated underneath the lower side of the first face ply. A displaceable liner coating comprising an enabler, a facilitator, and a stabilizer is formulated, and the layer of patterned adhesive is covered with the displaceable liner coating. The displaceable liner coating is activated by bringing the displaceable liner coating in contact with a fluid. The second face ply is secured to the first face ply using the activated displaceable liner coating such that the printable upper side faces away from the printable lower side. The first face ply is secured to the substrate, and the second face ply is sandwiched between the first face ply and the substrate.
US11559974B2 Microfluidic system or device and method of manufacturing a microfluidic system or device
A method of manufacturing a microfluidic system or microfluidic device having at least one channel includes providing a base sheet, providing a deformable intermediate layer, providing a cover film, and laminating the base sheet, the intermediate layer and the cover film so that a back surface of the intermediate layer is attached to a front surface of the base sheet and a back surface of the cover film is attached to a front surface of the intermediate layer opposite to the back surface thereof, thereby forming a laminate comprising the base sheet, the intermediate layer and the cover film. Further, the method includes applying pressure to the front surface of the intermediate layer through the cover film so as to deform the intermediate layer, thereby forming the at least one channel. The invention also relates to a microfluidic system or microfluidic device) manufactured by this method.
US11559972B2 Multilayer structure and use of same
A multilayer structure includes a layer of a resin composition containing an ethylene-vinyl alcohol copolymer and a thermoplastic elastomer, wherein a mass ratio of the ethylene-vinyl alcohol copolymer to the thermoplastic elastomer is from 65/35 to 95/5 and the layer of the resin composition has one surface directly adjacent to a layer of polyolefin with no polar functional group. A multilayer structure is thus provided that is excellent in gas barrier properties, transparency, and flexibility and also has good delamination properties between the layer of the resin composition and the layer of the polyolefin with no polar functional group.
US11559971B2 Conductive composite and method for manufacturing a conductive composite
A conductive composite includes a first layer of elastomeric polymer, a layer of electrically conductive paste on the first layer of elastomeric polymer, and a second layer of elastomeric polymer on the layer of electrically conductive paste. A reinforcement mesh is in contact with the layer of electrically conductive paste.
US11559967B2 Multifunctional surfacing films
The present invention is directed to multifunctional surfacing films each comprising: (a) a single layer of curable polymer composition having opposing first and second surfaces: (b) a peelable porous sheet disposed at or beneath the second surface; and (d) at least one porous sheet of functional material disposed within the single layer of curable polymer composition and positioned between the first surface and the peelable porous sheet, and methods of making and using such multifunctional surfacing films.
US11559966B2 Decorative member and manufacturing method therefor
The present disclosure relates to a decoration element comprising a light reflective layer, and a light absorbing layer provided on the light reflective layer and comprising Si.
US11559964B2 Composite structures, composite storage tanks, vehicles including such composite storage tanks, and related systems and methods
A composite storage tank may include a wall structure including at least three regions including an inner region, an outer region, and at least one permeation barrier. Another region may be optionally incorporated for venting potential permeation of fluids. The at least one permeation barrier and/or the venting layer may be strategically positioned between the inner region and the outer region to reduce or at least partially prevent fluid permeation of the inner region or the outer region. A vehicle may include such a composite storage tank. Methods of forming a composite fluid storage tank may include forming an inner composite region, applying a permeation barrier to an outer surface of the inner composite region, forming an outer composite region, and curing the inner composite region and the outer composite region with the permeation barrier to form the composite fluid storage tank.
US11559959B2 Machining method, application tool, and machining arrangement for modifying or repairing a surface spot of a workpiece surface of a fiber composite workpiece
To reduce the processing time in the case of repairing of excessively countersunk bolt openings or surface damage in fiber composite workpieces, it is proposed to countersink the corresponding surface spot to produce a contact surface and a depression for a fiber composite insert body. The fiber composite insert body is placed onto the contact surface and is fixed on the fiber composite workpiece in the depression. In the case of an excessively countersunk bolt opening, a new bolt opening is drilled into the fiber composite insert body, which new bolt opening is subsequently countersunk to the correct countersunk bore depth. In the case of the method, a three-legged application tool can be used which positions and orients the fiber composite insert body correctly and presses it onto the fiber composite workpiece during the curing of the adhesive.
US11559957B2 Reactivation of co-cured film layers
The present disclosure is directed to a method for reactivating a co-cured film layer disposed on a composite structure, the method comprising applying a reactivation treatment composition comprising at least two solvents and a surface exchange agent comprising a metal alkoxide or chelate thereof to the co-cured film layer, and allowing the reactivation treatment composition to create a reactivated co-cured film layer, wherein the co-cured film layer was previously cured at a curing temperature greater than about 50° C. A reactivated co-cured film layer and an aircraft part having a reactivated co-cured film layer are also provided.
US11559955B2 Molding of fiber blanks into three-dimensional fiber block articles
A fiber block molding apparatus comprising: —a mold having a lower part and an upper part forming between them a cavity for forming a fiber blank into a fiber block article upon closing the mold; —a conveyor system for receiving the fiber blank to be molded at a receiving position, transporting the fiber blank via a heater for activation of a binding agent, and delivering the heated fiber blank into the lower part of the mold at a delivery end of the conveyor system, and —a horizontal position shifting arrangement for shifting the horizontal position of the delivery end of the conveyor system relative to the lower part of the mold between a first and a second position to lay the fiber blank on the lower part of the mold.
US11559954B2 Multi-chamber conformable bladder for composite part tooling
A tool for forming a part includes a first tool portion including a first tool surface. The tool further includes a second tool portion comprising a second tool surface facing the first tool surface, wherein the first tool surface and the second tool surface define a tool chamber for forming the part. The tool further includes a bladder subassembly disposed in the tool chamber between the first tool surface and the second tool surface. The bladder subassembly includes a plurality of inner bladders disposed within tool chamber, wherein each inner bladder of the plurality of inner bladders includes an inner bladder chamber that is independently inflatable to selectively apply pressure to the part. The bladder subassembly further includes a bladder cover disposed over the plurality of inner bladders within the tool chamber to provide a barrier between the plurality of inner bladders and the part.
US11559948B2 Installing pipeline segments within a conduit
A method for installing pipeline segments within a conduit. The method includes a step of securing a first pipe segment of the pipeline segments at a top end of the conduit, a step of aligning a main axis of a second pipe segment of the pipeline segments with the main axis of the pipeline, a step of lifting the second pipe segment from a first position associated with a bottom end of the conduit to a second position adjacent to the first pipe segment, a step of abutting a top rim of the second pipe segment against a bottom rim of the first pipe segment, and a step of attaching the top rim of the second pipe segment to the bottom rim of the first pipe segment.
US11559944B2 High resolution electrohydrodynamic three-dimensional printing of high viscosity materials
A system and method for three-dimensionally printing high viscosity materials using electrohydrodynamics is provided. The system uses a relatively low voltage electric field to draw high viscosity polymers (not in solution) from a nozzle to form three-dimensional objects with lines less than 10 microns in width. Pressurized gas at the nozzle outlet can be used to print large size/dimension parts, instead of or in addition to the electric field to draw the polymers from the nozzle.
US11559936B2 Additive manufacturing processes employing a material featuring properties of a soft bodily tissue
Methods of fabricating three-dimensional objects featuring properties of a soft bodily tissue and three-dimensional objects featuring properties of a soft bodily tissue or of an organ comprising same are provided.
US11559932B2 Injection molding machine with part-handling apparatus
An injection molding machine includes a machine base; a stationary platen fixed to the base for holding a stationary mold section; a moving platen slidably supported by the base for holding a moving mold section; a rotary apparatus slidably supported by the base axially intermediate the stationary and moving platens for supporting a plurality of center mold sections and moving the center mold sections among axial positions directed toward the stationary and moving mold sections and lateral positions directed toward the operator and non-operator side of the machine; and a part-handling apparatus mounted to the stationary platen. The part-handling apparatus includes an end-of-arm tooling disposed laterally outboard of the rotary apparatus. The end-of-arm tooling is movable laterally between an engaged position for interacting with molded articles in one of the center mold sections in the lateral positions, and a disengaged position spaced laterally outwardly from the engaged position.
US11559929B2 Injection-moulding machine with an index shaft having a channel for a fluid
An injection-moulding machine, having a first platen, which is designed for carrying a first mould half of an injection mould, a second platen, which is designed for carrying a second mould half of the injection mould in such a way that in a closed state of the injection mould the first mould half and the second mould half delimit at least one cavity of the injection mould, and having an index shaft, which is mounted rotatably and axially adjustably on the injection-moulding machine outside the injection mould, is rotationally driven by of a motor of the injection-moulding machine arranged outside the injection mould and has an end portion which protrudes into the injection mould in the installed position of the injection mould in the injection-moulding machine, is designed for fastening on the index shaft an index plate to be arranged within the injection mould and has at least one channel which is designed to feed a fluid to the index plate or to remove a fluid from the index plate, wherein by means of the index shaft, driven by the motor, the index plate is automatically adjustable between a first plate position of the index plate and at least one second plate position of the index plate, and wherein the motor has a hollow motor shaft, through which the fluid is passed.
US11559927B2 Blowing agent introduction into hopper of polymer foam processing
Methods and systems that include introducing blowing agent into a hopper of a polymeric foam system.
US11559925B2 Patterned inflatable membrane
An inflatable membrane may include a pattern layer and a fluorescent layer, wherein the pattern layer comprises an inner surface and an outer surface, and a pattern on the inner surface of the pattern layer, wherein at least a portion of the pattern layer formed by transferring a transferrable material from a casting plate to the inner surface, and wherein the fluorescent layer comprises an inner surface and an outer surface, the inner surface of the fluorescent layer abutting the outer surface of the pattern layer and comprising a fluorescent material which, upon receiving of light, causes the fluorescent material to emit fluorescent light and causing the pattern to be detectable by a detector.
US11559919B2 Method for the application of mineral binder compositions containing fibres
A method for the application of hydrous mineral binder compositions which contain fibres. An aqueous accelerator is mixed with the aqueous binder composition in a mixer shortly before the application. The method is very robust and makes it possible to quickly produce even large moulded bodies having a uniform surface and very good strength development properties.
US11559917B2 Drop roller press and method of making recessed panel doors
The disclosure relates to systems and methods for pressing a door assembly involving a scanning system operable to survey an outer surface of a door skin and identify a location of one or more recessed panel portions on the door skin, and a press operable to selectably actuate a group of actuators based on the identified location of the recessed panel portions, where the actuators drive press members onto the one or more recessed panel portions of the door skin during a pressing operation to facilitate crushing of portions of a core of the door assembly that underlie the recessed panel portion of the door skin.
US11559915B2 Curve cutting with a circular saw blade
Method and calculating unit for curve sawing of a block in a cutting direction with at least a first circular saw blade. The method comprises determining a radius of the curve sawing, by measuring the curvature of the block in the direction of cutting; calculating a vertical inclination angle of the first circular saw blade in a vertical plane relative to the cutting direction in the block, based on the determined radius of the curve sawing; inclining the first circular saw blade with the calculated vertical inclination angle; and sawing the block in the cutting direction with the inclined first circular saw blade along the determined radius of the curve sawing.
US11559914B2 Cutting apparatus for foodstuffs
An apparatus includes a cutting surface that contains at least one cutting element having a top. The cutting element also has an interior sidewall extending from the cutting surface to the top with an interior sidewall angle, an exterior sidewall extending from the cutting surface to the top with an exterior sidewall angle and a shoulder provided on the interior sidewall between the base and the top. The interior sidewall angle is different than the exterior sidewall angle.
US11559908B2 Robot unit
A robot uni includes: a first link forming a center of rotation of the robot unit; a second link configured to perform a revolution motion or a rotation motion based on the center of rotation when rotated about the first link; first members, each of which is provided between the first link and the second link; drivers, each of which is provided in a direction that faces the first link and is configured to provide driving forces to the first members; wires configured to transmit the driving forces of the drivers to the first members; and second members, each of which is provided on the first link and the second link, is wound by the wires, and is configured to perform a revolution motion or a rotation motion along with the first link and the second link in a case where each of the first members is driven.
US11559903B2 Robotic toolset and gripper
A robot configured to use a gripper to grasp one or more tools is disclosed. In various embodiments, the robot comprises a robotic arm having a gripper disposed at a free moving end of the robotic arm, and a set of two or more tools configured to grasped or otherwise engaged by the gripper. Each tool in the set of two or more tools may be disposed in a corresponding tool holder, optionally attached to the robot or situated near the robot. The robot is configured to use the gripper to retrieve a selected tool from its tool holder to perform a task; use the tool to perform the task; and return the tool to its tool holder.
US11559896B2 Failure prediction system
A failure prediction system includes: a processor, the processor being configured to: collect torque values of a drive axis of a robot that is operating in accordance with a given work program; derive an evaluation formula approximating a time change of the torque value which is most recent from among the collected torque values set a failure threshold that is the torque value at which it is determined that failure of the drive axis occurs, based on the evaluation formula and the time change of the torque value when the drive axis reached failure in the past; and calculate an estimated value for the torque value when a prediction time set in advance has elapsed in the evaluation formula, and determines whether failure of the drive axis is predicted within the prediction time according to comparison between the estimated value and the failure threshold.
US11559895B2 Predictive robotic obstacle detection
Provided are systems and methods by which robots predictively detect objects that may obstruct robotic tasks prior to the robots performing those tasks. For instance, a robot may receive a task, and may obtain dimensions of a task object based on a first identifier obtained with the task or with a sensor of the robot. The robot may determine a first boundary for moving the task object based on the task object dimensions and an added buffer of space that accounts for imprecise robotic operation. The robot may detect a second identifier of a neighboring object, and may obtain dimensions of the neighboring object using the second identifier. The robot may compute a second boundary of the neighboring object based on the dimensions of the neighboring object and a position of the second identifier, and may detect an obstruction based on the second boundary crossing into the first boundary.
US11559894B2 Object handling control device, object handling device, object handling method, and computer program product
An object handling control device includes one or more processors configured to acquire at least object information and status information representing an initial position and a destination of an object; set, when a grasper grasping the object moves from the initial position to the destination, a first region, a second region, and a third region in accordance with the object information and the status information; and calculate a moving route along which the object is moved from the initial position to the destination with reference to the first region, the second region, and the third region.
US11559892B2 Self-propelled travelling apparatus, information processing apparatus, and non-transitory computer readable medium
A self-propelled travelling apparatus includes a travelling controller that controls travelling of the self-propelled travelling apparatus; a receiving unit that receives merchandise and a message associated with the merchandise from a user during travelling of the self-propelled travelling apparatus; and a supplying unit that supplies the message to another user in a case where the other user receives the merchandise while the self-propelled travelling apparatus is travelling after receiving the merchandise and the message.
US11559890B2 Method, apparatus and system for determining a trajectory of a robot's end effector
A method and apparatus for determining a trajectory of a robot's end effector are disclosed. In an embodiment, the apparatus includes a force obtaining device to obtain a collision force of the end effector of the robot, caused by a collision of the end effector upon the collision being detected; and a trajectory determining device to determine a second trajectory of the end effector based on the collision force of the end effector obtained, and based on a recorded first trajectory of the end effector. The recorded first trajectory is a trajectory recorded before the collision, and the second trajectory is a trajectory determined after the collision. As such, an efficient protection for the robot and its working environment at the moment of collision may be achieved.
US11559888B2 Annotation device
An annotation device includes an image-capturing device, a robot, a control unit, a designation unit, a coordinate processing unit, and a storage unit. The control unit controls the robot so as to acquire a learning image of a plurality of objects, each having a different positional relationship with the image-capturing devices. Furthermore, the storage unit converts a position of the object in a robot coordinate system into a position of the object in an image coordinate system at the time of image-capturing or a position of the object in a sensor coordinate system, and stores the position thus converted together with the learning image.
US11559884B2 Systems and methods for a passive grasping surface on an active grasping robotic manipulator
One or more embodiments of the present disclosure relate generally to the field of robotic grasping systems, and in particular to an active robotic manipulator that includes a passive grasping component so that the robotic manipulator can grasp a wide variety of objects and simultaneously provide soft grasping features which reduce the risk of damage to objects.
US11559880B1 Adjustment tool for gymnastics uneven bars apparatus
An adjustment tool for adjusting a height of an upper bar of a gymnastics uneven bars apparatus. The adjustment tool is comprised of a shaft having a handle at one end and a horizontally-facing hook at an opposed end. In another embodiment, the hook faces upwards. The hook is sized and shaped to receive the upper bar, and is formed with a pair of outwardly flaring lips to allow the hook to be guided onto the bar without causing damage thereto. The handle is typically formed into a hook resembling that of a cane. A shaft length in an adjustable embodiment is comprised of two or more telescoping members mating with one another to establish and maintain desired shaft length.
US11559877B2 Staple removing device
A staple removing device includes a device body, a removing part provided in the device body and configured to execute a staple removing operation of removing a staple from a sheet bundle, an accommodation unit detachably mounted to the device body and configured to accommodate the staple removed by the removing part, a count unit configured to count a number of operation times of the staple removing operation, a detection unit configured to detect whether the accommodation unit is attached or detached with respect to the device body, a measurement unit configured to measure an elapsed time after the detection unit detects that the accommodation unit is removed from the device body, and an operation-times reset unit that resets the number of operation times when the elapsed time becomes a predetermined time or longer.
US11559873B2 Polishing tool holder and polishing device
A polishing device (1) includes a polishing brush (3) and a polishing brush holder (4) that holds the polishing brush (3). The polishing brush holder (4) includes a shank (6), a support mechanism (21) that has a sleeve (7) and supports the polishing brush (3) so as to be movable in an axial direction L of the shank (6), and a moving mechanism (22) that moves the polishing brush (3) in the axial direction L. The polishing brush holder (4) includes a pressure sensor (53) that detects a load (sensor detection pressure (P)) applied from a workpiece (W) to the polishing brush (3) when the workpiece (W) is polished by the polishing brush (3) supported by the support mechanism (21), and a control unit (51) that drives the moving mechanism (22) on the basis of the output (sensor detection pressure (P)) from the pressure sensor (53) to move the polishing brush (3) in the axial direction L.
US11559869B2 Wafer edge polishing apparatus and method
A wafer edge polishing apparatus includes a cleaning mechanism exhibiting a superb effect of cleaning slurry residue adhered on a chuck table. This edge polishing device is provided with: a chuck table which sucks/holds a wafer; a rotation drive mechanism which rotates the chuck table; an edge polishing unit which polishes an edge of the wafer while supplying slurry to the wafer, which is rotating while being sucked/held by the chuck table; and a cleaning unit which removes slurry residue on the chuck table. The cleaning unit includes a cleaning head, and cleans the chuck table through high-pressure cleaning and brush-cleaning by using the cleaning head, wherein the cleaning head is provided with a high-pressure jet nozzle and a brush surrounding the periphery of the high-pressure jet nozzle.
US11559868B2 Wheel machining equipment
Wheel machining equipment is provided, including a first-stage turning system used for carrying out first-stage turning of a wheel, a high-precision connection system used for carrying out high-precision positioning conversion from first-stage turning to second-stage turning, and a second-stage turning system used for carrying out second-stage turning of the wheel. A wheel machining method is also provided.
US11559865B2 Scraper for scraping a surface of a machine tool having a wear-indicating device
The present invention relates to a scraper (14) for scraping a surface of a machine tool having a wear-indicating device (18, 20, 24, 30) for the scraper lip (16) of the scraper. At least one signal line (18) is embedded in the scraper lip (16) in such a manner that, upon reaching the wear limit (G), at least one section of the signal line (18) is exposed.
US11559862B1 Power tool
A power tool includes a wrench head having a rotary socket, and a spanner tool mounted in the rotary socket, wherein the rotary socket grips a first component and the spanner tool grips a second components, the first and second component being adjacent.
US11559860B2 Welding wires formed from improved aluminum-magnesium alloys
Aluminum-magnesium alloys useful as welding wire and mechanical support are disclosed. The aluminum-magnesium alloys exhibit improved cold wire drawing performance. Grain refiners and methods of forming the aluminum-magnesium alloys are further disclosed.
US11559856B2 Laser cutter adapted to cut rotating workpieces
A desktop laser cutter configured to cut a cylindrical workpiece includes a laser, a cutting head that receives an electromagnetic beam from the laser and emits a cutting beam, and a gantry that supports the cutting head relative to a base plate of the laser cutter housing. The gantry can be actuated to move the cutting head within a plane that is parallel to the baseplate. The cutting head emits the cutting beam in a direction parallel to the plane. In use, the cutting head is disposed side-by-side with the workpiece and the cutting beam is applied to a side of the workpiece that faces a sidewall of the laser cutter housing. The workpiece is supported by the gantry to rotate an amount that is a function of movement of the cutting head in a direction parallel to the plane.
US11559853B2 Method for scanning the surface of metal workpieces and method for carrying out a welding process
Method for scanning the surface (O) of metallic workpieces (W), wherein, during a scanning process before a welding process is carried out, a welding torch (1) with a meltable welding wire (2) is moved over the surface (O) of the workpieces (W), and at predefined times (ti) the welding wire (2) is moved towards the surface (O) of the workpieces (W) until a contact of the welding wire (2) with one of the workpieces (W) is detected, and the position (Pi) of the surface (O) of the workpieces (W) at each time (ti) is determined and stored in the welding power source (4), wherein an edge (K) is determined if the current position (Pi) of the surface (O) of the workpieces (W) exceeds at least one of the stored previous positions (Pi-n) of the surface (O) of the workpieces (W) by a predefined threshold value (S). To reduce the computing effort and to increase processing speed, the end of the edge (K) is determined if the current position (Pi) of the surface (O) of the workpieces (W) remains the same with respect to at least one of the stored previous positions (Pi-n), and if an edge (K) is determined, an edge detection parameter (KP) is set and output together with the current position value (Pi) and transferred to the manipulator (3).
US11559852B2 Thin-film devices and fabrication
Thin-film devices, for example electrochromic devices for windows, and methods of manufacturing are described. Particular focus is given to methods of patterning optical devices. Various edge deletion and isolation scribes are performed, for example, to ensure the optical device has appropriate isolation from any edge defects. Methods described herein apply to any thin-film device having one or more material layers sandwiched between two thin film electrical conductor layers. The described methods create novel optical device configurations.
US11559851B2 Laser machining device and laser machining method
A unit vector calculating unit of a laser machining device obtains a unit vector based on respective current rotational positions of an A-axis and a B-axis. A movement command calculating unit, a speed command calculating unit, or a torque command calculating unit generates a command signal for maintaining a gap amount at a constant value, based on the unit vector, and the gap amount between a machining nozzle and a workpiece. With a servo control unit, on the basis of the command signal, an X-axis motor, a Y-axis motor, and a Z-axis motor are controlled, whereby the machining nozzle is moved relatively in three-dimensional directions with respect to the workpiece.
US11559847B2 Superalloy part and method of processing
A method for repairing a part and the resulting is disclosed. The method includes positioning a plug having an inner braze element coupled thereto into a cavity defined by an internal surface of a component. The cavity has a circular cross-section at the external surface of the component. The plug completely fills the circular cross-section and the inner braze element is within the cavity. A braze paste is positioned at least partially around the plug at the external surface. The component is positioned such that the inner braze element is above the plug. The component is subjected to a thermal cycle to melt the inner braze element around the plug, completely sealing the cavity by forming a metallurgical bond with the plug and the internal surface of the component. During the thermal cycle the braze paste is melted to form a metallurgical bond with the plug and external surface.
US11559845B2 Method of repairing a region of a part including a threaded hole
Methods of repairing a periphery of a threaded hole of a part are provided. An embodiment of the method includes adding material to a region of the part including on a periphery of the threaded hole. New threads are formed in the added material. The new threads are continuous with existing threads formed in the hole.
US11559841B2 Electromechanical shears for vertical cutting
The electromechanical vertical cutting shear (1) comprises an electric servomotor (4) combined with a gear reducer (5) at least one shaft (6) bearing one or more spools (7), at least one motion transmission means (8) which is connected to a guillotine (11), and a cutting system comprising at least a pair of knives (12). The electromechanical shear (1) comprises a pulley system (9) for every motion transmission means (8).
US11559836B2 Pull-type blind fastener with preload performance
A blind pull type fastener includes a pin, a sleeve, a collar, and a bulb-forming portion. The pin includes a head. The pin is pulled so that the head applies force to the bulb-forming portion. The bulb-forming portion is deformed to form a bulb. The collar is deformed into a void of the sleeve. The pin includes locking rings. The collar is deformed to lock with the locking rings.
US11559833B2 Dynamic straightening method for left/right tilt
A dynamic straightening method for a left/right tilt. The method includes: drawing an unevenness curve according to a distance from a shapemeter to a surface of a plate, where there are a plurality of unevenness curves; using a barycentric formula to obtain a first barycentric coordinate of each unevenness curve; calculating a tilt value of a straightening roll corresponding to each unevenness curve according to the first barycentric coordinate of each unevenness curve; determining an unevenness curve of a current straightening roll; adjusting the straightening roll according to the tilt value of the straightening roll corresponding to the unevenness curve, to straighten the plate; and going back to the step of determining an unevenness curve of a current straightening roll until the plate is totally straightened. Such method improves plate straightening accuracy by dynamically adjusting parameters of the straightening roll.
US11559832B2 Cylindrical tube formation
Tube forming methods can be used for efficient transition in the production of tubes having varying thickness. Material used to form consecutive tubes may have the same thickness along a separation plane separating a first discrete section from a second discrete section of the material, and the first discrete section and the second discrete section may each have varying thickness in a feed direction of the material. With such a thickness profile, the first discrete section of the material may be formed into a first cylinder having varying thickness and separated from the second discrete portion as the second discrete section is formed into a second cylinder having varying thickness. In particular, the transition between the first cylinder and the second cylinder may be achieved without scrap and/or interruption, resulting in cost-savings and improvements in production throughput associated with forming tubes having varying thickness.
US11559824B2 Method for producing a structure on a surface
A method for manufacturing a structure on a surface of a workpiece (1) is disclosed, the method having the following steps: applying a liquid base layer (2) onto the surface of the workpiece (1); spraying on at least one droplet (3) into the not yet congealed base layer (2), wherein the at least one droplet (3) at least partially, preferably completely, penetrates into the base layer (2); fixing the base layer (2); and at least partially removing the at least one droplet (3). Further, a second method having the following steps is disclosed: spraying on at least one droplet (3) onto the surface of the workpiece (1); applying a liquid base layer (2) onto the surface of the workpiece (1), wherein the base layer (2) flows around the at least one droplet (3) and preferably at least partially covers the at least one droplet (3); fixing the base layer (2); at least partially removing the at least one droplet (3). Finally, a device for performing the methods is disclosed.
US11559817B2 Using electrokinetic forces to manipulate suspended particles
Devices and methods for capturing biological materials using a potential well. An electrical signal is applied across a nanopipette having one end in a back-fill chamber and another end in a collection chamber containing a suspending medium including one or more types of particles. The collection end of the nanopipette includes a tip having an opening. The electrical signal applied across the nanopipette is configured to generate the potential well proximate to the tip in which the electrokinetic forces acting on the particles are balanced. The potential well may be configured to selectively trap one or the other types of particles suspended in the suspending medium. The particles may be transferred to a sample collection medium by immersing the tip in the sample collection medium and reversing the polarity of the electrical signal.
US11559814B2 Double acting demolition device and utility machine for demolishing structures
The application relates to a double acting demolition device according to one embodiment for demolishing structures. The device includes a first crushing jaw for crushing operation, a first cutting jaw for cutting operation, and a combination jaw. The first jaws are separate jaws. The combination jaw is attachable to the first cutting jaw for constructing a second crushing jaw and to the first crushing jaw for constructing a second cutting jaw. The second crushing jaw is used jointly with the first crushing jaw in crushing operation and the second cutting jaw is used jointly with the first cutting jaw in cutting operation. In crushing operation, the first crushing jaw rotates around a fulcrum other than that of the second cutting jaw in cutting operation.
US11559813B2 Safety cabinet
Provided is a safety cabinet that reduces a temperature change between a storage environment temperature and a temperature in the safety cabinet to reduce damage to cultured microorganisms, cultured cells, or the like. The safety cabinet that includes a front panel and an operation opening in front of an operation space and an operation stage below the operation space and supplies purified air into the operation space from above, in which the operation stage is provided with a temperature-regulatable portion of which a temperature is regulatable.
US11559810B2 Method and apparatus for coding diagnostic meters
A system for diagnostic testing may include a meter for performing a diagnostic test on a sample applied to a test media, the meter having a housing and an interface for receiving a signal representing coding information, and a container configured to contain test media compatible with the meter, the container having a coding element associated therewith. Additionally, the system may provide a mechanism for removing the meter from an interconnected test container and reattaching it to a new container using on-container coding methods that can recalibrate the meter for the new container of test strips.
US11559809B2 Enhanced cell/bead encapsulation methods and apparatuses
A method of encapsulating a solid sample in a droplet, the method including flowing a continuous phase through a first fluid channel at a first flow rate; flowing a dispersed phase through a second fluid channel at a second flow rate, the dispersed phase including a plurality of particles, cells or beads; trapping the plurality of particles, cells or beads in a mixing region that receives the dispersed phase and the continuous phase; and reducing the first flow rate to encapsulate the trapped particles, cells or beads in droplets of the dispersed phase generated when the dispersed phase and the continuous phase exit the mixing region through an orifice.
US11559807B2 System and method for precision detection of biomarkers
A method for detecting biomarkers with shortened test time and maximized precision. A sample from the body fluid is made to flow over a sensor surface coated with a capture antibody to allow binding of a biomarker in the sample to the capture body. An optical method detects and counts the individual binding events along the sensor surface with single molecule resolution, and difference in the binding events along the sensor surface is detected in real time and analyzed to determine the biomarker concentration.
US11559806B2 Acoustic wave sorting
The present invention generally relates to the manipulation of species using acoustic waves such as surface acoustic waves. In some aspects, a channel such as a microfluidic channel may be provided having two or more outlets, and acoustic waves applied to species within the channel to determine which outlet the species is directed to. For instance, surface acoustic waves may be applied to a species such as a cell or a particle to deflect it from the channel into a groove or other portion that directs it to a different outlet. In some cases, surprisingly, this deflection of species may be in a different direction than the incident acoustic waves on the channel. Other embodiments of the present invention are generally directed to kits including such systems, techniques for producing such systems, or the like.
US11559800B2 Device for locking a volume adjustment screw for a pipetting system
A device for locking a volume adjustment screw for a pipetting system, comprising a control member which rotates as one with a position selector, the member cooperating with a locking wheel such that: when the selector is in the free adjustment position, the member ensures that the wheel is axially spaced from another wheel, such that the teeth of the wheels do not cooperate with each other; when the selector is in the fine adjustment position, the member allows the wheel to move away from and then to move axially towards the other wheel while transitioning from one tooth to another; when the selector is in the locking position, the member axially locks the wheel to prevent the teeth from being disengaged.
US11559799B2 Removable impingement basket for ethylene oxide (EO) reactors
An ethylene oxide (EO) reactor is provided in which a removable impingement basket is configured to be inserted into the reactor inlet pipe of the EO reactor. The removable impingement basket provides protection for the silver-based catalyst filled tubes and other components that are present inside the EO reactor as well as providing another access point into the EO reactor. The removable impingement basket also can provide better distribution of the inlet gas as compared to an EO reactor containing a non-removable impingement plate.
US11559797B2 Acyclic carbene ligand for ruthenium complex formation, ruthenium complex catalyst, and use thereof
Provided are a novel acyclic carbene ligand for ruthenium complex formation; a ruthenium complex catalyst using the ligand; a method of using the complex as a catalyst in an ethylene-metathesis ethenolysis reaction; a method of preparing the ruthenium complex catalyst; and a method of preparing a linear alpha-olefin, the method including the step of reacting a linear or cyclic alkene compound in the presence of the ruthenium complex catalyst.The acyclic carbene ligand of the present invention and the ruthenium complex catalyst using the same have high selectivity and turnover number for terminal olefin formation in an ethylene-metathesis ethenolysis reaction, and thus linear α-olefins may be prepared with a high yield.
US11559792B2 Zinc manganese-iron spinel with an alkali metal stabilizer as an oxygen storage material resistant to rich/lean aging
An oxygen storage material (OSM) includes a zinc manganese iron oxide (ZMF) and an alkali metal base on the ZMF surface. The ZMF has a spinel structure. The alkali metal containing ZMF can be formed to have a weight percent of alkali metal up to about two percent. The alkali metal carbonate is retained on the ZMF surface upon heating to a temperature greater than 1,000° C. and stabilizes the ZMF to the cycling of an oxygen rich and oxygen lean atmosphere. The OSM additionally catalyzes the oxidation of hydrocarbons and CO and catalyzes the reduction of NOx for use in catalytic converters.
US11559789B2 Base oil hydrotreating catalyst and process of use
An improved hydrotreating catalyst and process for making a base oil product wherein the catalyst comprises a base extrudate that includes a high nanopore volume amorphous silica alumina (ASA) and a second amorphous silica alumina. The catalyst and process generally involve the use of a base extrudate comprising the high nanopore volume ASA and the second ASA in a catalyst to produce hydrotreated dewaxed base oil products by contacting the catalyst with a hydrocarbon feedstock. The catalyst base extrudate advantageously comprises a first amorphous silica alumina having a pore volume in the 11-20 nm pore diameter range of 0.2 to 1.0 cc/g and a second amorphous silica alumina having a pore volume in the 11-20 nm pore diameter range of 0.02 to 0.2 cc/g, with the base extrudate formed from the amorphous silica alumina and the alumina having a total pore volume in the 2-50 nm pore diameter range of 0.12 to 1.80 cc/g. The catalyst further comprises at least one modifier element from Groups 6 to 10 and Group 14 of the Periodic Table. The catalyst and process provide improved aromatics saturation.
US11559787B2 Compositions, methods, and apparatuses for catalytic combustion
There is provided a catalyst composition including a hydrogen oxidation catalyst and an oxygen reduction catalyst and a process for applying the catalyst composition to a substrate. Heat exchange reactors including the catalyst composition and methods for heating a heat exchange medium are also provided. Catalytic combustors including a catalytic surface including the catalyst composition are further provided. The catalyst is adapted for low temperature activation of a hydrogen combustion reaction.
US11559781B2 Process for manufacturing a material with a high specific surface area
A manufacturing process that includes spray-drying a liquid composition based on liquid residues derived from a chemical extraction of clinker to form a material with a high specific surface area. Also, a material based on clinker residues having a high specific surface area ranging from 200 m2.g−1 to 900 m2.g−1 and a mesopore size ranging from 2 nm to 50 nm. Further, the use of a material having a high specific surface area for the absorption of pollutants species.
US11559780B2 Reverse flow reactors with selective flue gas management
Systems and methods are provided for improving the operation of groups of reverse flow reactors by operating reactors in a regeneration portion of the reaction cycle to have improved flue gas management. The flue gas from reactor(s) at a later portion of the regeneration step can be selectively used for recycle back to the reactors as a diluent/heat transport fluid. The flue gas from a reactor earlier in a regeneration step can be preferentially used as the gas vented from the system to maintain the desired volume of gas within the system. This results in preferential use of higher temperature flue gas for recycle and lower temperature flue gas for venting from the system. This improved use of flue gas within a reaction system including reverse flow reactors can allow for improved reaction performance while reducing or minimizing heat losses during the regeneration portion of the reaction cycle.
US11559776B2 Method for improving the cooling capacity of a gas solids olefin polymerization reactor
The present invention relates to a method for improving the cooling capacity of a gas solids olefin polymerization reactor by splitting the fluidization gas and returning part of the fluidization gas to the reactor into the bottom zone of the reactor and another part of the fluidization gas directly into the dense phase formed by particles of a polymer of the at least one olefin suspended in an upwards flowing stream of the fluidization gas in the middle zone of the reactor.
US11559775B2 Equal flow scale catcher
An equal flow scale catcher device, or EFSC, is designed based on a unique scale catching technology for a reactor. With multiple scale catching modules, the EFSC offers equal flows to a catalyst bed or distribution tray of the reactor, independent of each module's degree of saturation with particles of an incoming fluid during operation. Thus, the innovative EFSC system achieves substantial uniformity of fluid delivery across the distribution tray of the reactor and the static pressure field above the liquid level on the distribution tray. Further, the EFSC effectively captures solid particles in the incoming fluid to the reactor and solid particles that form at the top head of the reactor. The EFSC employs a modular structure that allows optimal configuration of the scale catching modules and scale catching units inside each scale catching module, thus efficiently facilitating simple and efficient installation, maintenance, and/or replacement of the EFSC.
US11559772B2 Graphene membrane filter for gas separation
The invention relates to carbon supported crack- and tear-free graphene membranes of large area useful for selective gas separation, method of preparation and uses thereof. In particular, the invention relates to carbon supported crack- and tear-free graphene membranes having good gas separation performance, in particular high H2 permeance and H2/CH4 selectivities.
US11559771B2 Method for manufacturing zeolite membrane structure
A method for manufacturing a zeolite membrane structure comprises an immersion step for immersing a porous substrate in a synthetic sol, and a synthesis step for hydrothermally synthesizing a zeolite membrane on a surface of the porous substrate that has been immersed in the synthesis so. When the foamability of the synthetic sol is measured by a Ross-Miles method under a condition of 25 degrees C., the foam height after elapse of 5 minutes from completion of down flow is less than or equal to 5 mm.
US11559770B2 Small volume processing systems and methods with capacitive sensing
A fluid processing system may include a flow control cassette comprising at least one interface sensor chamber in fluid communication with at least one of a plurality of separate channels, the at least one interface sensor chamber defined at least in part by a wall, and at least one capacitive sensor disposed on the wall of the at least one interface sensor chamber. The fluid processing system may include, in the alternative or in addition, at least one syringe comprising a wall defining a barrel having a first end and a second end, the barrel having a bore with or without a piston or plunger disposed therein, and at least one capacitive sensor disposed on an outer surface of the wall of the syringe.
US11559768B2 Exhaust gas purification catalyst
The present disclosure provides the exhaust gas purification catalyst with the improved purification performance under the high Ga condition and the transient state in which an A/F repeats rich and lean phases. The present disclosure relates to an exhaust gas purification catalyst comprising a catalyst coating layer on a substrate, the catalyst coating layer containing a noble metal, a composite oxide containing cerium oxide and zirconium oxide, and a composite oxide containing aluminum oxide, wherein in the catalyst coating layer: an average thickness of the coating layer is in a range from 20 μm to 100 μm; a porosity measured by a weight-in-water method is in a range from 50% by volume to 80% by volume; and high-aspect-ratio pores having an aspect ratio of 5 or more account for 0.5% by volume to 50% by volume of a whole volume of voids, the high-aspect-ratio pore having an equivalent circle diameter in a range from 2 μm to 50 μm in a cross-sectional image of a catalyst coating layer cross section perpendicular to an exhaust gas flow direction of the substrate and having an average aspect ratio in a range from 10 to 50, and wherein the noble metal is supported on peripheries of the voids, the composite oxide containing the cerium oxide and the zirconium oxide, and the composite oxide containing the aluminum oxide.
US11559767B2 Method for carbon dioxide capture and sequestration using alkaline industrial wastes
A method of sequestering gaseous carbon dioxide in which an oxide is carbonated by contacting it with a first aqueous carbonate solution to convert a portion of the oxide into a carbonate, which precipitates from solution. By converting the oxide to a solid carbonate, the CO2 from the first carbonate solution is sequestered into the precipitate. At the same time, an aqueous hydroxide solution is formed. The aqueous hydroxide solution is contacted with gaseous carbon dioxide which sequesters the gaseous CO2 into a second aqueous carbonate solution. The second solution so generated is then recycled back into the process and used to convert the oxide into the precipitated carbonate.
US11559766B2 Alkali-based removal of chemical moieties from gas streams with chemical co-generation
The present disclosure provides systems and methods useful in capture of one more moieties (e.g., carbon dioxide) from a gas stream (i.e., direct air capture). In various embodiments, the systems and methods can utilize at least a scrubbing unit, a regeneration unit, and an electrolysis unit whereby an alkali solution can be used to strip the moiety (e.g., carbon dioxide) from the gas stream, the removed moiety can be regenerated and optionally purified for capture or other use, and a formed salt can be subjected to electrolysis to recycle the alkali solution back to the scrubber for re-use with simultaneous production of one or more further chemicals.
US11559765B2 Systems and methods for recovering water using a refrigeration system of a water recovery system
Systems and methods for operating a water recovery system are described and include activating a condenser of the water recovery system. The method includes measuring a temperature associated with the condenser based on data obtained from a condenser temperature sensor. The method includes comparing the temperature associated with the condenser to a maximum threshold temperature. The method includes activating an auxiliary condenser of the water recovery system in response to the temperature associated with the condenser being greater than the maximum threshold temperature.
US11559759B2 Water filter
A filter arrangement includes: a chamber including a chamber inlet for unfiltered liquid, a chamber outlet for filtered liquid and a wall arranged to keep the unfiltered liquid and the filtered liquid separated, a filter element having a longitudinal extension arranged inside of the chamber, wherein the filter element includes a semi-permeable filtration wall including a folded filter arranged in a zig-zag configuration between an inner perforated cylinder and an outer perforated cylinder and an internally located back-washing arrangement. The back-washing arrangement includes: an elongated and hollow body having a longitudinal extension, which is substantially parallel to the longitudinal extension of the filter element, a mechanism configured to drive the body in a rotational and/or an axial movement, a plurality of nozzles arranged in fluid communication with a cavity inside of the body, the plurality of nozzles projecting laterally from the body such that a distal end of each of the plurality of nozzles is arranged in close proximity to the inner perforated cylinder and an outlet arranged in fluid communication with the cavity of the elongated and hollow body and wherein the plurality of nozzles are arranged parallel to each other along a straight line on the body such that they all project in the same direction.
US11559757B2 Water filtration apparatus
Aspects of the present disclosure relate to an apparatus for filtering a fluid. One exemplary aspect including a casing having an interior cavity and extending between a fluid inlet and a fluid outlet at opposed ends thereof, a tube sheet assembly spanning the interior cavity the tube sheet assembly having a plurality bores therethrough and a plurality of filter media tubes each extending from one of the plurality of bores in the tube sheet assembly. In some exemplary aspects, the tube sheet assembly may comprise a plurality of retaining plates sandwiched together with a tube sheet plate. In some exemplary aspects, the apparatus may further comprise at least one restrictor plate adapted to obstruct at least one of the plurality of bores of the tube sheet.
US11559756B2 Centrifugal fuel purifying apparatus
The present invention discloses a centrifugal fuel purifying apparatus, including, a center shaft, a centrifugal cylinder, a shaft seat, a rotating skeleton, a disc type guide plate, a fuel gathering impeller, a rotating wheel, a vacuum pump, a fuel outlet pipe, a fuel inlet, pipe, a fuel unloading box, a pollutant receiving box, a tank body and a PLC controller, wherein the alarm fuel tank is arranged at the top in a tank body of the fuel tank, a fuel level meter is disposed within the alarm fuel tank, a fuel inlet is provided on the upper part of one side of the alarm fuel tank above the fuel level meter, a fuel outlet is provided on the lower part of one side of the alarm fuel tank below the fuel level meter, and the fuel inlet is communicated with the centrifugal cylinder through the fuel inlet pipe.
US11559746B1 Feedback oriented gameplay sessions in video games
Systems and methods are described herein for monitoring a gameplay session for violations of a policy and creating a remediation gameplay session through which remediation can be provided to players or player accounts that violate gameplay policies. The systems and methods can create a remediation gameplay session based in part on the game state data of the gameplay session during which the violation occurs.
US11559745B2 Video modification and transmission using tokens
Modified video is distributed to a viewer of a computer-implemented game by causing a processor to distribute, toward a terminal device of a viewer, a first video including an animation of a first avatar of a distributor generated based on motion data; distribute, toward the terminal device, a second video related to a computer-implemented game generated with operation data using a received web page; receive, from the terminal device, token data indicative of a token sent to the distributor from the viewer during execution of one unit section of the game; and distribute, toward the terminal device, the second video including, during one time section occurring after the one unit section of the game ends and before a next unit section of the game begins, a rendering of a token object selected based on the token data.
US11559743B2 Cross-pollination of in-game events, assets and persistent communications using signs and likes across virtual environments in gaming sessions of a video game
A method for connecting game plays between different players playing a video game. The method includes determining that a first character has accomplished a mission within a region of a virtual environment of the video game, wherein the first character is controlled by a first player playing the video game in a first game play. The method includes opening access by the first character to a regional inter-game communication medium in response to accomplishing the task. The method includes generating first data in the first game play. The method includes cross-pollinating the first data using the regional inter-game communication medium across a plurality of virtual environments of a plurality of asynchronous game plays of a plurality of players.
US11559741B2 Systems and methods to provide audible output based on section of content being presented
A device provides audible output pertaining to audio video (AV) content such as a video game based on a section of the AV content that is being presented.
US11559738B2 Machine learned virtual gaming environment
Virtual game worlds for computer games can be provided using machine learning. The use of machine learning enables the virtual game worlds to be generated at run time by standard consumer hardware devices. Machine learning agents are trained in advance to the characteristics of the particular game world. Then, these suitably trained machine learning agents can be used to generate a relevant portion of a virtual game world, such as a portion of the virtual game world that is proximate to a play's position. Advantageously, the virtual game world can be provided in high resolution and is able to cover a substantially larger region than conventional practical.
US11559734B2 Surface orientation sensing structure and intelligent magic cube
The present invention discloses a surface orientation sensing structure, where six printed circuit boards are combined to form a regular hexahedron as the axis of an intelligent magic cube, and a main control chipset can recognize layer rotation by simply sweeping a copper foil through a brush sheet to cause a level change, so that the position change of the layer can be recognized more accurately, a step loss rate is reduced, parts are reduced, and the assembly process is simplified. The present invention further discloses an intelligent magic cube, where all the parts related to orientation sensing are concentrated on the axis, so that the intelligent magic cube can be operated more easily and smoothly, the intelligent functions of the intelligent magic cube can be used more smoothly, and user experience is improved.
US11559733B2 Ice skate
A blade holder for an ice skate (e.g., for playing hockey). The ice skate comprises a skate boot for receiving a foot of a skater. The blade holder comprises a blade-retaining base to retain a blade. The blade-retaining base comprises a first material (e.g., a non-composite polymeric material). The blade holder comprises a support extending upwardly from the blade-retaining base to interconnect the blade holder and the skate boot. The support comprises a second material (e.g., a composite material) different from (e.g., stiffer than) the first material.
US11559725B1 Lighted sports ball, kit, and method of use thereof
A lighted sports ball is provided. The lighted sports ball includes an interior housing through which light can pass. The interior housing features a cavity within the interior housing. The lighted sports ball further includes a circuit board mounted to the interior housing. The circuit board is connected to a battery and has a light module as well as a controller for controlling an output of the at least one light module. An exterior cover is applied over the interior housing. The exterior cover has an aperture through which light from the light module can pass. Further, a lighted sports ball kit including a lighted sports ball and a charging stand is provided. Furthermore, a method for using the lighted sports ball is provided.
US11559721B2 Cycling device
A cycling device used for exercise and/or rehabilitation includes a shaft for grasping by a user, a foot assembly coupled to the shaft and configured to be supported on a surface, and a pedal assembly coupled between the shaft and the foot assembly. The cycling device is intended to be used by a seated user.
US11559719B2 Training apparatus
Training apparatus comprises exercise equipment mounted to a side surface or a roof of a land vehicle or for mounting to a surface such as a wall of a building or ship. The exercise equipment comprises a support structure which is attached to the surface or roof. In some embodiments the support structure is maneuverable by pivoting with respect to the surface or roof, whilst remaining attached thereto, between a stowed condition and an exercising condition.
US11559718B2 Barbell spotting apparatus
Provided herein are embodiments of a barbell spotting apparatus having all the benefits of a free-floating, unconstrained barbell in both the horizontal and vertical axes with the safety of a dedicated spotting mechanism, while addressing safety, noise, and space concerns raised by typical barbell apparatus. The embodiments herein permit a loaded barbell to be positioned in line with the axis of motion of the lift to be performed at both the beginning and end of the lift.
US11559711B2 Foam producing method, fire extinguishing method, and appliance for foam extinguishing
A foam production method includes mixing liquid nitrogen with a foaming material to produce foam. A gas is produced in situ from liquid nitrogen. As the ratio of the volume of the gas produced by gasification of liquid nitrogen to the volume of the liquid nitrogen is relatively high, when a large gas supply flow is needed to generate a large foam flow, a liquid nitrogen storage device of a small volume can be used instead of bulky air supply devices such as high-pressure gas cylinders, air compressors, air compressor sets and the like, reducing the volume of the air supply device. In addition, the liquid nitrogen used in foaming will release nitrogen gas after the foam blast, such that the nitrogen is also able to inhibit combustion on the surface of burning materials, accelerating the extinguishing of the fire.
US11559708B2 Electronic respirator mask
An electronic respiratory mask capable of filtering air that passes through is disclosed herein. In an embodiment, a face mask includes a body having an inner volume that surrounds the user's mouth when the body is placed over the user's mouth, a first electrode located on the body, the first electrode sized and shaped to allow air to pass between the inner volume of the body and an outside environment when the body is placed over the user's mouth, and a second electrode located on the body, the second electrode sized and shaped to allow air to pass between the inner volume of the body and the outside environment when the body is placed over the user's mouth, wherein the first and second electrode create an electric field gradient that is capable of suspending microbes as air passes between the inner volume of the body and the outside environment.
US11559706B2 Work safety management system using safety belt unit for high-place work
The present disclosure relates to a work safety management system using a safety belt unit for high-place work, and safety during working at a high place can be enhanced by determining whether a worker has fastened a seat belt to a safety structure, and the location of the worker, whether the seat belt is fastened and whether the work is on progress can be monitored in real time from a remote location to prevent safety accidents.
US11559703B2 Technologies for energy-modulated radiation therapy
Described are devices, systems, and methods for modulating the spectral energy distribution produced by an x-ray source via control of the energy of the x-ray-generating electron beam, e.g., for energy-modulated radiation therapy or other purposes. In some embodiments, such energy modulation is achieved by an add-on device to a linear accelerator. Also disclosed are computational methods and computer program products for planning energy-modulated therapy.
US11559700B2 Implantable fasteners, applicators, and methods for brachytherapy
A fastener applicator includes a body portion including a handle assembly, a cartridge assembly supported within the body portion, the cartridge assembly including implantable fasteners, a drive assembly supported within the body portion and operatively coupled to the cartridge assembly to engage the implantable fasteners, and an actuation assembly supported within the handle assembly and operatively coupled to the drive assembly to fire a distal-most implantable fastener upon actuation of the actuation assembly. At least one of the implantable fasteners includes a body including a tissue facing surface, a tissue penetrating portion extending from the body, and a capsule affixed to the tissue facing surface of the body, the capsule including radioactive material.
US11559696B2 Implantable medical device for arrhythmia detection
A computer implemented method for determining heart arrhythmias based on cardiac activity that includes under control of one or more processors of an implantable medical device (IMD) configured with specific executable instructions to obtain far field cardiac activity (CA) signals at electrodes located remote from the heart, and obtain acceleration signatures, at an accelerometer of the IMD, indicative of heart sounds generated during the cardiac beats. The IMD is also configured with specific executable instructions to declare a candidate arrhythmia based on a characteristic of at least one R-R interval from the cardiac beats, and evaluate the acceleration signatures for ventricular events (VEs) to re-assess a presence or absence of at least one R-wave from the cardiac beats and based thereon confirming or denying the candidate arrhythmia.
US11559677B2 Tube connector for medical treatment
Disclosed is a tube connector for medical treatment including a housing including an internal channel configured to allow an inflow pipe disposed at the front end thereof and an outflow pipe disposed at the rear end thereof to fluidly communicate with each other, an insertion hole formed from the outer surface of the rear end of the housing to the internal channel, and at least one branch pipe disposed so as to fluidly communicate with the internal channel, a push button having a through hole, the push button being disposed in the insertion hole so as to be movable upwards and downwards, and an elastically deformable dome-shaped balloon configured to surround the insertion hole of the housing, the lower part of the balloon being open, wherein the internal channel of the housing is opened and closed through the upward and downward movement of the push button.
US11559675B1 Tattoo machine rechargeable battery unit with voltage controller
A compact battery and voltage supply controller apparatus for a tattoo machine is disclosed. The battery and controller are configured to connect the battery to the tattoo machine through replaceable internally received magnetic connection adapters. The toggle switch operated display screen provides easy-to-view status and health of the battery and incremental voltage adjustment using a voltage boost circuit and adjustment knob. The internal battery can be replaced and/or removed and recharged.
US11559672B2 Left atrial appendage stasis reduction
Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.
US11559668B2 Drug-elution control sleeve for drug-eluting balloon and method
An apparatus, assembly and method for controlling release of a drug from a drug-eluting balloon during delivery of a drug-eluting balloon to a situs within a body. More particularly, the present invention relates to a diametrically expandable sleeve having a first non-diametrically unexpanded state in which drug retained on or in a drug-eluting balloon is protected from release by a sleeve and a second diametrically expanded state in which drug retained on or in the drug-eluting balloon is exposed for focal release in the body by diametric expansion of the sleeve, exposing openings in the sleeve during diametric expansion and closing the openings in the sleeve when the sleeve is in its diametrically unexpanded state.
US11559667B2 Guidewire retaining accessory
A guidewire support accessory includes one or more hollow tubular sections, each of the hollow tubular sections including a first end and an opposing second end for individually supporting a plurality of medical guidewires. A connector is disposed at the first end. Each of the one or more hollow tubular sections is sized and configured to receive a medical guidewire maintained in a coiled arrangement. The accessory includes at least one clamp configured to releasably retain a guidewire in the coiled arrangement, as well as at least one wiping or cleaning feature.
US11559665B2 Midline catheter placement device
A catheter insertion device is provided for positioning and inserting a catheter, particularly a midline catheter into a patient. The insertion device includes an actuator assembly movable with respect to a housing for deploying the catheter over a needle. A step-wise movement of the actuator advances a catheter assembly, including the catheter, in stages over the introducer needle. An indexing finger of the catheter assembly engages the actuator body during distal advancement of the actuator, and deflects as the actuator is moved proximally. The device further includes a lockout device such as a button, collar, slider, or tab, which allows movement of the catheter relative to the needle but prevents advancement of the catheter to the first stage of the step-wise movement.
US11559654B2 Humidifier
A device is provided that humidifies breathing gas. The device has a chamber with an inlet and an outlet. A chemical heater is positioned within the chamber and a trigger activates the heater. The chamber can be a conduit with an inner wall and an outer wall with a reservoir defined therebetween. The chemical heater can be positioned within the reservoir.
US11559653B2 Respiratory humidification system
A system provides warm, humidified pas to a patient via a patient interface. Horizontal connections can be used between the humidification chamber and conduit. To reduce the likelihood of condensate flowing back to the humidification chamber, or dead space or gases recirculation regions occurring within the gases flow path, a raised portion is positioned inside of the flow path to improve flow characteristics and to provide a barrier for condensate back flow. The raised portion also reduces the amount of condensate that is formed in the system and provides better flow characteristics for sensing purposes.
US11559651B2 Apparatus and method for oxygen delivery to a patient during manual ventilation
A system for detecting manual ventilation and selectively delivering a high flow of oxygen. The system comprises a source of compressed oxygen coupled to a first lumen of a nasal cannula, with an oxygen flow control valve coupled to a processor to control the flow of oxygen to the nasal cannula. A second lumen of the nasal cannula is in connection with a pressure sensor and the pressure sensor in connection with the processor. The processor may receive the pressure values and be programmed to determine when manual ventilation has occurred, and send a signal to the oxygen flow control valve to send a high flow of oxygen in response to manual ventilation.
US11559650B2 Breathing assistance apparatus
A mask assembly for use as part of an apparatus for supplying a flow of respiratory gases to a user is disclosed. The mask assembly includes a mask body having an inlet through which said flow of respiratory gases are provided to the interior of said mask body. A mask seal assembly comprising a seal of flexible material and a clip of rigid material is attached to the body. The seal has a first side and a second side. The first side of the seal is shaped to approximately match the contours of a user's face and in use substantially seal against a user's face. The second side is attached to the clip. The clip provides an interface extending substantially the full perimeter or periphery of the mask seal assembly for releasably attaching the mask seal assembly to the mask body. The clip comprises a bridging portion spanning outwards from the perimeter or periphery of the mask body to space at least a portion of the second side of the seal outwards from the perimeter or periphery of the mask body.
US11559648B2 Patient interface with movable frame
A patient interface may include a plenum chamber pressurisable to a therapeutic pressure; a seal-forming structure constructed and arranged to form a seal with a region of the patient's face; a positioning and stabilising structure to provide an elastic force to hold the seal-forming structure on the patient's head, the positioning and stabilising structure may include a tie; a vent structure; a decoupling structure configured to provide a fluid connection between the plenum chamber and an air circuit for the flow of air at the therapeutic pressure for breathing by the patient; and a frame having at least one tie attachment structure to receive the tie, wherein the frame is configured to be resiliently movable in any direction having at least one of a component parallel to the patient's sagittal plane, a component parallel to the patient's coronal plane, a component parallel to the patient's Frankfort horizontal plane.
US11559646B1 System and method for video assisted percutaneous needle cricothyrotomy and tracheostomy
A system and method for video assisted percutaneous needle cricothyrotomy and tracheostomy to assist physicians in quickly intubating patients suffering from respiratory distress when oral or nasal intubation is not possible or contraindicated. The system and method includes a display monitor, a percutaneous needle assembly including a connection hub having a syringe port for removably attaching a syringe, a needle port for attaching a hollow needle, and a stylet port in communication with the needle port for receiving a fiber optic stylet that extends through the hollow needle. The fiber optic stylet includes one or more illuminators, and a camera for capturing and transmitting anatomical images for display on the display monitor to visually assist physicians in locating a patient's trachea lumen. The fiber optic stylet is positioned within the trachea lumen, and used as a guide wire to insert a dilator and cannula for ventilating the patient.
US11559645B2 Ventilation system with electrochemical filter for alkyl phenols and method using the electrochemical filter
A ventilation system includes an electrochemical filter for depleting alkyl phenols, especially 2,6-diisopropyl phenol, in breathing gas. A method uses the filter for removing alkyl phenols, especially 2,6-diisopropyl phenol, from breathing gas.
US11559643B2 Systems and methods for ventilation of patients
A mechanical ventilator is provided that includes a dashboard display identifying a patient's current ventilatory status within a global or universal ventilatory mechanics map. This dashboard display is dynamically updated with the patient's condition, and shows trends in the patient's ventilation over time. The map identifies suggested safe and unsafe regions of ventilation for the patient, and the ventilator can display informational texts, trigger auditory and/or visual alarms, and transmit alarm communications in response to determining that the patient is approaching or has entered an unsafe region.
US11559639B2 Weight-balanced flavor aspirators
A flavor aspirator includes: a weight-concentrated part that is provided at a position off the mouthpiece end and closer to the mouthpiece end side than to a midpoint position between the mouthpiece end and the distal end, and that accounts for at least approximately half of a total weight of the flavor aspirator. A value of (a length from the mouthpiece end to the center of gravity)/(a total length defined by a length from the mouthpiece end to the distal end) is in a range of 0.20 to 0.45.
US11559637B2 Inhalers and related methods
An inhaler (10) has a main body for accommodating a medicament reservoir (84), a canister fire system for moving a canister (50) to release a dose in response to air flow, a cap housing (12) for enclosing the canister fire system and canister within an interior chamber defined by the main body (14) and a cap housing, wherein a lock system (250) is provided for locking the cap housing on the main body.
US11559636B2 Warming device and infusion system
Provided is a warming device which can efficiently warm a blood product and inhibit a liquid in a warming flow path from exceeding an upper limit temperature thereof when liquid delivery of the blood product is stopped. The warming device includes the warming flow path in which the blood product flows and a heat plate which is in contact with the warming flow path to supply heat to the warming flow path. On the heat plate, a heater in a predetermined pattern corresponding to the warming flow path is disposed. The heater is disposed such that an amount of heat generation toward the warming flow path decreases in stages from an upstream side toward a downstream side in the warming flow path and that a decrease rate of the amount of heat generation at each of the stages decreases from the upstream side toward the downstream side.
US11559635B2 Needle insertion device
The present invention generally provides a device for inserting needles and alleviating the discomfort associated with needle insertion. In certain embodiments, the device is suited for injecting butterfly needles and particularly butterfly needles that are attached to infusion tubing. The patient or caregiver loads a butterfly needle with tubing attached into the base of the drive plunger. The needle with tubing attached is retracted into the housing of the device by retracting the inner plunger. Once retracted, the device is activated and ready to administer a needle into the tissue of a patient. The device is then placed on the location of the skin where injection is desired. The surface that contacts the skin may be textured and may include a contact switch that causes the device to vibrate when slight pressure is applied through contact with the skin. Two trigger buttons in the housing of the device may be depressed to eject the needle at an angle essentially perpendicular to the surface of the skin into the tissue of the patient concurrently with the textured pads contacting the skin and vibrating, distracting the patient from the needle insertion. The inner plunger of the device is then depressed toward the surface of the skin to release the needle from the device. The wings and body of the butterfly may be secured to the skin, for example, with an adhesive such as tape.
US11559633B2 Syringe adapter with spinning connector
A syringe adapter includes a housing having a first end and a second end and defining an interior space, a seal arrangement received within the interior space of the housing, a connector body positioned adjacent the first end of the housing and configured to be connected with a syringe barrel with the connector body secured to the housing and rotatable relative to the housing in first and second directions, and a cannula secured to the connector body. The connector body is axially fixed relative to the housing. The seal arrangement is configured to cooperate with the cannula to provide a sealed transfer of fluids through the cannula to a mating connector.
US11559632B2 Passive safety needle shield
A passive safety needle shield (300) is provided. The needle shield comprises a base (302) fixed to a proximal end of a needle, and an enclosure housing (304) initially disposed at a distal end of the needle, and enclosing the end of the needle. A hinged arm (306) connects the base (302) and the enclosure housing (304). The enclosure housing (304) is slidable along the needle length, and the hinged arm (306) flexes to permit the enclosure housing (304) to move along the needle as the needle is inserted into a user, thereby hiding the needle end, and providing support to the needle to avoid bends or buckles in the needle. The hinged arm (306) is biases in the initial position so that the enclosure housing (304) returns to the end of the needle as the needle is withdrawn.
US11559629B2 Determining a status of an injection
An electronic device (104) comprising: a housing (203) for attachment to an injection device (102); a first sensor assembly (304) comprising a first coil (406a) and two magnets (402a, 404a) of opposite polarity, wherein the first coil (406a) is configured to provide a first voltage pulse as a first Wiegand wire (224) of the injection device (102) moves from a first position proximate to one of the magnets (402a) of the first sensor assembly (304) to a second position proximate to the other magnet (404a) of the first sensor assembly (304); and one or more processors (308) configured to enter an enabled state from a sleep state after receiving the first voltage pulse from the first coil (406a).
US11559627B2 Autoinjector with a needle cover
The invention relates to an autoinjector 59 for administering a fluid medicament to a subject comprising: a housing 1 for receiving a cartridge holder; a driver assembly 8; the driver assembly on actuation may move the cartridge 3 forward in the cartridge holder 2; a needle cover 4 may be coupled to the housing wherein the needle cover 4 travels in a linear or translational movement; said needle cover 4 is adapted to protect a needle when the needle cover may be in first locking position 17 and second locking position 18; the linear or translational movement may be achieved by a cam profile 13 and a cam follower 14; the cam profile 13 may be provided on outside surface of housing and the cam follower 14 located between the needle cover 4 and the housing 1; a first biasing member 15; and a second biasing member 16 configured to bias the cartridge 3 and the needle cover 4 respectively; and a safety cap 11 to control the actuation of the autoinjector. The needle cover 4 further comprises a sleeve 91 or sleeve 92 which prevents or inhibits the obstruction of the movement of needle cover 4 when the user accidentally hold the needle cover 4 during actuation of the autoinjector.
US11559622B2 Deformation resistant wound therapy apparatus and related methods of use
The wound therapy apparatus may include a wound interface sealingly securable to the skin surface around a wound bed to encloses the wound bed within an enclosed space that is fluid-tight. The wound interface may be sufficiently deformation resistant to distend at least a portion of the wound bed into the enclosed space when pressure p0 within the enclosed space is less than ambient pressure pamb. Fluid may be communicated with the enclosed space when the wound interface is sealingly secured to the skin surface in order to vary a pressure p0 within the enclosed space periodically over the pressure range pmin≤p0≤pmax. The variation of the pressure p0 may distend the wound bed into communication with a pad received within the enclosed space and decreases the wound bed contact with the pad. Related methods of use of the wound therapy apparatus are also disclosed.
US11559621B2 Method and apparatus for filtering
Embodiments of the present disclosure provide a method and apparatus for filtering and surgical procedures. An exemplary apparatus includes an evacuation tube having a filter, a long axis and a hollow conduit extending through the long axis, the hollow conduit fluidly connecting a tube inlet and a tube outlet, the filter located within the hollow conduit operable to remove particles from a flow passing through the hollow conduit from the tube inlet to the tube outlet.
US11559619B2 Systems and methods for controlling dual mode negative pressure wound therapy apparatus
In some embodiments, a negative pressure wound therapy device includes a negative pressure source and a controller configured to, in response to determining that the negative pressure source is directly fluidically connected to a wound dressing without a canister between the two, operate the negative pressure source in a first mode; otherwise, operate the negative pressure source in a second, different mode. The controller can be further configured to, in response to determining that a level of activity of the negative pressure source over a first time duration satisfies at least one of a leak or blockage condition, provide an indication of at least one of a leak or blockage and, in response to determining that the level of activity does not satisfy the at least one of the leak or blockage condition over a second time duration subsequent to the first time duration, discontinue providing the indication.
US11559617B2 System and method for opening a concentrate container and connecting the concentrate container to a blood treatment device
The present invention refers to a system and method for opening a concentrate container without the need for a human to directly handle the concentrate container and connecting the concentrate container to a blood treatment device. Aspects of the invention are directed to a container for concentrate and a blood treatment device.
US11559610B2 Low temperature cured silicone lubricious coatings
Novel, lubricious coatings for medical devices are disclosed. The coatings provide improved lubricity and durability and are readily applied in coating processes a low temperatures that do not deform the device. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.
US11559608B2 Fabrication of autologous bone
Described herein are methods and apparatus for constructing tissue replacements, such as bone replacements that may be used to repair damaged or missing segments of bone, such as may occur in wound repair or as a repair of a congenital anomaly. These methods involve a three-dimensional (3D) cell growth medium made from a yield stress material that allows cells and structures to be easily deposited and positioned.
US11559605B2 Kidney production method
The present invention provides a kidney production method including a step of tissue-specifically removing a metanephric mesenchyme of a metanephros of a non-human animal; a step of transplanting, into the metanephros, a kidney precursor cell derived from a non-human animal which is allogeneic or xenogeneic to the non-human animal; and a step of advancing development of the metanephros, which is a step in which the transplanted kidney precursor cell is differentiated and matured to form a part of the kidney.
US11559604B2 Nerve conduits
The invention provides bioresorbable nerve guidance conduits made from polymer blends which include polyhydroxyalkanoates (PHAs). In particular, the invention provides nerve guidance conduits having a body which comprises a polymer blend comprising: (a) from 60 to 98 wt. % of a first component which is a PHA copolymer comprising two or more different medium chain length hydroxyalkanoate monomer units; and (b) from 2 to 40 wt. % of a second component which is either a PHA homopolymer containing a short chain length hydroxyalkanoate monomer unit, or a polylactide (PLA). The invention further relates to polymer blends comprising (a) and (b).
US11559603B2 High-strength collagen sponge
To provide a collagen sponge excellent in mechanical strength and a production method for the collagen sponge. A collagen sponge including a porous construct having a pore structure, the collagen sponge having a tensile strength of 1 N or more and 5 N or less in every direction including a length direction and a width direction. The collagen sponge may be produced by a production method including the following steps: (1) a step of subjecting a collagen solution obtained by mixing collagen and a solvent to stirring and deaeration treatment; (2) a step of subjecting the collagen solution to freeze-dry treatment; and (3) a step of subjecting a dried collagen product after the freeze-dry treatment to insoluble treatment.
US11559602B2 Sol for tissue perforation closure, ulcer protection, and vascular embolization
The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.
US11559595B2 Currency and document sanitizing apparatus and system
A sanitizing system for sanitizing currency bills at a retailer has a sanitizing apparatus that has an inlet for the insertion therethrough currency bills by a customer, the sanitizing apparatus including a reader for reading the currency bills to establish the total monetary value thereof, and for issuing a receipt to the customer reflecting the total monetary value. A reader located adjacent a cash register at the retailer reads the receipt and accepts the total monetary value as cash tender for merchandize being purchased. A counterfeit detector tests the currency bills and rejects currency bills that do not meet predetermined genuine criteria.
US11559593B2 Ultraviolet disinfection device
The present device provides a safe, effective means of mobile ultraviolet (UV) disinfection. A control board within the main body of the device receives data from sensors that may variously measure orientation and speed of the main body as it moves along various surfaces for disinfection. In response to such data, the control board may brighten, dim, or completely shut off UV light-emitting diodes (UVLEs), both to prevent over- and under-exposure of the materials being disinfected, and to prevent a user from unsafely using the device.
US11559588B2 Materials and methods for treatment of Spinocerebellar Ataxia Type 1 (SCA1) and other Spinocerebellar Ataxia Type 1 Protein (ATXN1) gene related conditions or disorders
The present disclosure provides materials and methods for treating a patient with one or more conditions or disorders associated with ATXN1 whether ex vivo or in vivo. For example, the present disclosure provides materials and methods for treating a patient with Spinocerebellar ataxia type 1 (SCA1). Also provided are materials and methods for editing a ATXN1 gene in a cell by genome editing. The present disclosure also provides materials and methods for altering the contiguous genomic sequence of a ATXN1 gene in a cell. In addition, the present disclosure provides one or more gRNAs for editing a ATXN1 gene. Also provided are therapeutics comprising at least one or more gRNAs for editing a ATXN1 gene. In addition, the present disclosure provides therapeutics for treating patients with a ATXN1 related condition or disorder.
US11559583B2 Anti-CSF1R antibody and agonistic anti-CD40 antibody combination therapy for cancer
Methods of treating cancer with antibodies that bind colony stimulating factor 1 receptor (CSF1R) in combination with one or more immune stimulating agents are provided.
US11559581B2 Antibody conjugates and methods of making the antibody conjugates
Described herein are antibody conjugates and methods of making antibody conjugates.
US11559580B1 Tissue-homing peptide conjugates and methods of use thereof
Peptides that home, target, migrate to, are directed to, are retained by, or accumulate in and/or bind to the cartilage or kidney of a subject are disclosed. Pharmaceutical compositions and uses for peptides or peptide-active agent complexes comprising such peptides are also disclosed. Such compositions can be formulated for targeted delivery of an active agent to a target region, tissue, structure or cell in the cartilage. Targeted compositions of the disclosure can deliver peptide or peptide-active agent complexes to target regions, tissues, structures, or cells targeted by the peptide.
US11559575B2 Multi-epitopic peptide compounds and vaccines against leishmaniasis
The invention relates to multi-epitopic peptide compounds obtained from PSA, HwB and LmLRAB proteins of Leishmania as well as to pharmaceutical compositions and vaccines for use against one or more leishmaniases.
US11559574B2 Whole-cell cancer vaccines and methods for selection thereof
The present invention provides a modified human cancer cell comprising a recombinant polynucleotide encoding an allele of a human leukocyte antigen gene. The present invention also provides methods for selecting a whole-cell cancer vaccine for a subject having cancer and methods of treating cancer using whole-cell cancer vaccines of the present invention. In addition, the present invention provides a method of determining the HER2 status of a cell. Compositions and kits are also provided herein.
US11559573B2 Method of eliciting a CD8+ cytotoxic response in hepatocellular carcinoma patients with a population of activated T cells
A method of eliciting an immune response in a patient who has a cancer includes administering to said patient a composition containing a population of activated T cells that selectively recognize the cancer cells in the patient that aberrantly express a peptide consisting of the amino acid sequence of GVYDGEEHSV (SEQ ID NO: 303), in which the peptide is in a complex with an MHC molecule.
US11559564B2 Use of a VEGF antagonist to treat angiogenic eye disorders
The present invention provides methods for treating angiogenic eye disorders by sequentially administering multiple doses of a VEGF antagonist to a patient. The methods of the present invention include the administration of multiple doses of a VEGF antagonist to a patient at a frequency of once every 8 or more weeks. The methods of the present invention are useful for the treatment of angiogenic eye disorders such as age related macular degeneration, diabetic retinopathy, diabetic macular edema, central retinal vein occlusion, branch retinal vein occlusion, and corneal neovascularization.
US11559559B2 Angiotensin II alone or in combination for the treatment of hypotension
The present invention relates, inter alia, to a method comprising administering to a subject having high output shock and undergoing treatment with a catecholamine at a dose equivalent to at least about 0.2 mcg/kg/min of norepinephrine a dose of angiotensin II which is effective to raise the blood pressure of the subject to a mean arterial pressure (MAP) of about 65 mm Hg or above, and which is effective to reduce the dose of the catecholamine required to maintain a MAP of about 65 mm Hg to the equivalent of about 0.05-0.2 mcg/kg/min norepinephrine or less, or to the equivalent of about 0.05 mcg/kg/min norepinephrine or less.
US11559554B2 Multifiber prebiotic composition for digestive health, weight control, boosting immunity and improving health
A composition composed of xylooligosaccharide, arabinogalactan, inulin, Ganoderma lucidum beta glucan, insoluble yeast β (1, 3/1, 6)-glucan, soluble oat β (1,3/1, 4)-glucan, and insoluble dried Saccharomyces cerevisiae fermentate, with a Bacillus coagulans component, for use in improving or maintaining digestive health, weight and glucose balance and boosting immunity is provided.
US11559552B2 Methods and compositions for purification or isolation of microvesicles and exosomes
The invention relates to the isolation or extraction of exosomes.
US11559550B2 Peptides and combination of peptides for use in immunotherapy against leukemias and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11559544B2 Combination of a MAPK/ERK pathway inhibitor and a glycosaminoglycan for the treatment of cancer
A negatively charged glycosaminoglycan is provided for use as a medicament for the treatment of cancer. A combined administration of a negatively charged glycosaminoglycan is provided in which the glycosaminoglycan is characterised by the absence of the terminal pentasaccharide of Heparin, and an inhibitor of the MAPK/ERK pathway. A combined administration of a glycosaminoglycan and a MAPK/ERK pathway inhibitor is provided as a medicament for the treatment of cancer types that exhibit a resistance towards a single MAPK/ERK pathway inhibitor treatment.
US11559540B2 Method of determining acute myeloid leukemia response to treatment with farnesyltransferase inhibitors
The disclosed method rapidly identifies with desired accuracy AML patients, including elderly AML patients, likely to respond to treatment with a combination of a farnesyltransferase inhibitor and one or more of etoposide, teniposide, tamoxifen, sorafenib, paclitaxel, temozolomide, topotecan, trastuzumab and cisplatinum. In an embodiment, the improvements include the use of whole blood rather than the customary bone marrow sample, thus making the assay more accurate, rapid, less intrusive, less expensive as well as less painful. The method includes evaluation of a two-gene expression ratio (RASGRP1:APTX), which with a corresponding threshold, provides sufficient accuracy for predicting the response to the combination treatment. In the preferred embodiment the combination treatment combines tipifarnib (R115777, ZARNESTRA®) with etoposide. Further, the elderly AML patients identified as being likely responsive to the combination treatment with tipinifarb and etoposide have a complete recovery rate comparable to the best therapy available for younger patients.
US11559539B2 Human milk oligosaccharide for improving immune fitness
The invention concerns the use of fucosylated non-digestible human milk oligosaccharide, or a composition comprising a fucosylated non-digestible human milk oligosaccharide, for use in improving immune fitness in a human subject, wherein the human subject is male.
US11559529B2 Compositions comprising Omega-3 fatty acids, 17-HDHA and 18-HEPE and methods of using same
The present invention relates to a polyunsaturated fatty acid composition comprising Omega-3 fatty acids, 17-HDHA and 18-HEPE. The composition can furthermore comprise DPA and/or an acceptable carrier and can be present in a capsule or other suitable dosage unit. The invention also relates to the process of obtaining the composition and methods for using same.
US11559528B2 BACE1 inhibition for the treatment of cancer
Provided herein are compositions, systems, kits, and methods for treating a subject with cancer by administering a BACE1 inhibitor, such as MK-8931. In particular embodiments, the subject is treated with radiation (e.g., low dose radiation) first, and then administered a BACE1 inhibitor within a certain time window (e.g., about 3 hours to 6 days after the radiation treatment).
US11559527B2 Targeting mitochondrial fission through mDIVI-1 derivatives
Derivatives of mDIVI-1 may be used to target and eliminate cancer stem cells. Disruption in the mitochondrial dynamics balance plays a role in cancer. Proteins involved in regulating mitochondrial dynamics represent potential targets for cancer treatment. Mitochondrial fission protein DRP1 is such a target. Derivatives of mDIVI-1 inhibit DRP1, and have demonstrated inhibition of tumorsphere forming capacity, migration and stemness-related signaling in breast cancer cells. These properties result from induction of mitochondrial oxidative stress and reduction of mitochondrial metabolism in the target cancer cells. The potency of an mDIVI-1 derivative may be dramatically increased through addition of at least one membrane-targeting signal and/or a mitochondria-targeting signal.
US11559525B2 Therapeutic drug for dyskinesia
The present invention provides a therapeutic drug that is useful for levodopa induced dyskinesia in Parkinson's disease. In particular, the present invention provides a composition and method for treating, improving, delaying the progression, or preventing motor complications associated with levodopa therapy for Parkinson's disease, especially levodopa induced dyskinesia (PD-LID), comprising tandospirone or a pharmaceutically acceptable salt or prodrug thereof, wherein the tandospirone or a pharmaceutically acceptable salt or prodrug thereof is parenterally administered.
US11559522B2 Methods for enhancing liver regeneration
The invention includes methods, kits, and pharmaceutical compositions for enhancing liver regeneration in a mammal in need thereof, comprising administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity. The methods may include administering a therapeutically effective amount of an agent that increases nicotinamide adenine dinucleotide (NAD) activity and a sirtuin 1 (Sirt1) agonist. The agent that increases NAD activity may be a NAD precursor. The NAD precursor may include one or more of tryptophan, nicotinic acid, nicotinic acid riboside, nicotinamide riboside (NR), nicotinamide, NADP, and NAD itself, and a pharmaceutically acceptable salt thereof.
US11559521B2 Analgesic formulations and methods for reduced postoperative nausea and vomiting and enhanced postoperative pain relief
A multimodal anti-emetic anesthetic/analgesic formulation for pain control not limited to postoperative pain control is described herein. The opioid-free/sparing anesthetic/analgesic formulation comprises a local anesthetic, an N-methyl-D-aspartate (NMDA) receptor antagonist, and a cyclooxygenase (COX) inhibitor such as Bupivacaine Hydrochloride, Ketamine Hydrochloride, and Ketorolac Tromethamine, which is effective to significantly reduce postoperative nausea and vomiting and enhance postoperative pain relief as compared to existing prior art anesthetics/analgesics. The formulation is administered to a mammal in need of anesthesia/analgesia and can be used as a preemptive and preventative multimodal analgesic. The formulation may have a buffer to enhance its shelf life and improve pharmacokinetics. The formulation may further comprise an alpha agonist, a steroid, a Transient Receptor Potential Channel agonist or antagonist, a beta-lactam antibiotic, a protein kinase inhibitor, a competitive or non-competitive glycine or glutamate antagonist, a glutamate or glycine inhibitor, a cyclooxygenase 3 inhibitor, or combinations thereof.
US11559518B2 Endoplasmic reticulum stress regulator comprising benzothiazoimidazolyl compound
A compound of general formula (1) [wherein: R1 and R2, which are the same or different, each represent a hydrogen atom, a halogen atom, a lower alkyl group, a lower cycloalkyl group, a lower alkanoyl group, a halogen substituted lower alkyl group, a lower alkoxy group, a halogen substituted lower alkoxy group, a cyano group, a cross-linked methylenedioxy group, an ethylenedioxy group, a propylenedioxy group, a lower alkylthio group, a lower alkylsulfonyl group, a carboxyl group, a lower alkoxycarbonyl group, a lower alkylamide group, a lower alkylamino alkylene amide group, an amino group, an alkylamino group, a hydroxy group, a functional group represented by general formula (2), or a functional group represented by general formula (3) —CONH(CH2)p—R3  (2) [wherein R3 represents a di-lower alkylamino group, a morpholino group, a piperidino group, a 2-methyl-piperidino group, or a 2-oxo-pyrrolidinyl group; p represents an integer from 2 to 6]; [wherein, R4 represents a lower alkyl group]; m and n each represent an integer from 0 to 3; the term lower represents a carbon number of 1 to 6; and the halogen atom represents a fluorine, chlorine or bromine atom] can inhibit endoplasmic reticulum stress to a greater extent as compared to known chemical chaperones. The compound thus can be used suitably as an agent for preventing, ameliorating or treating various diseases that are caused by endoplasmic reticulum stress.
US11559513B2 PTGDR-1 and/or PTGDR-2 antagonists for preventing and/or treating systemic lupus erythematosus
The present invention concerns a PTGDR-1 antagonist, a PTGDR-2 antagonist, a dual PTGDR-1/PTGDR-1 antagonist, or a combination of PTGDR-1 antagonist and PTGDR-2 antagonist, and pharmaceutical compositions containing them, for use for preventing and/or treating SLE.
US11559512B2 Composition for prevention, alleviation, and/or treatment of heat illness
This application provides a composition for preventing, alleviating and/or treating a heat illness, or cytotoxicity of cells such as vascular endothelial cells caused by load of heat stress and/or aberration associated with the production and release of a fever-inducing inflammatory cytokine(s) from blood cells caused by load of heat stress in a subject, comprising at least one substance selected from the group consisting of auraptene, tangeretin, and medium chain fatty acid as an active ingredient.
US11559511B2 Tannin-containing gastrointestinal formulations and methods of use
Tannin-containing compositions and methods of using same to enhance or maintain immune function during simplified nutrition feeding. Pharmaceutical compositions, including enteral nutrition compositions, are provided. The compositions comprise such tannins as proanthocyanidins and/or hydrolysable tannins. Administering the tannins to the gastrointestinal tract of a subject receiving simplified nutrition, such as with enteral nutrition therapy or parenteral nutrition therapy, attenuates or prevents deleterious effects on the gastrointestinal immune system that would otherwise occur with the simplified nutrition.
US11559509B2 Purified forms of rofecoxib, methods of manufacture and use
The subject matter disclosed herein relates to rofecoxib, also known as TRM-201 or RXB-201, its method of manufacture, and use. In certain aspects, the highly pure or substantially pure rofecoxib as provided herein has a favorable purity profile and is the active ingredient in a pharmaceutical composition that is administered to treat or prevent a number of conditions, including pain associated with a condition caused by a bleeding disorder.
US11559507B2 Pharmaceutical composition
A pharmaceutical composition is described. The composition comprises: (i) at least one formoterol compound selected from formoterol, pharmaceutically acceptable salts of formoterol, prodrugs of formoterol, solvates of formoterol, solvates of pharmaceutically acceptable salts of formoterol and solvates of prodrugs of formoterol; (ii) at least one corticosteroid; (iii) a surfactant component comprising at least one surfactant compound; and (iv) a propellant component comprising 1,1-difluoroethane (R-152a).
US11559505B2 Pharmaceutical composition
A pharmaceutical composition is described. The composition comprises: (i) at least one formoterol compound selected from formoterol, pharmaceutically acceptable salts of formoterol, prodrugs of formoterol, solvates of formoterol, solvates of pharmaceutically acceptable salts of formoterol and solvates of prodrugs of formoterol; (ii) at least one corticosteroid; (iii) a surfactant component comprising at least one surfactant compound; and (iv) a propellant component comprising 1,1-difluoroethane (R-152a).
US11559502B2 Treatment of menstrual cycle-induced symptoms
The present invention relates to methods of treatment of menstrual cycle induced disorders and symptoms with cathinone, particularly methods employing 3-methyl methcathinone (3-MMC). The present invention also relates to kits comprising 3-MMC for use in the treatment of subjects suffering from menstrual cycle induced disorders and symptoms. In particular, methods and kits for therapy of menstrual cycle induced disorders and symptoms with 3-MMC for a variety of disorders and/or conditions, including PMS, PMDD and perimenstrual disorders are provided.
US11559501B2 Transdermal amphetamine compositions with low levels of carbamate
Described are methods for reducing the formation of amphetamine carbamate and amphetacarbamate in transdermal amphetamine compositions, compositions with low levels of amphetacarbamate, and methods using such compositions for transdermal delivery of amphetamine.
US11559495B1 Icariin nano-pharmaceutical formulation
A nano-pharmaceutical formulation, comprising zein nanoparticles, icariin (ICA) or a pharmaceutically acceptable salt thereof encapsulated within the zein nanoparticles, at least one solubilizer, wherein the at least one solubilizer comprises D-a-Tocopherol polyethylene glycol 1000 succinate (TPGS), and one or more pharmaceutical penetration enhancers is provided. Methods of enhancing libido by administering a composition as described herein is also provided.
US11559494B2 Compositions and methods for targeted delivery of therapeutic and/or diagnostic species
In one aspect, compositions are described herein. A composition described herein comprises a nanoparticle, a therapeutic species, and a linker joining the nanoparticle to the therapeutic species. The linker joining the nanoparticle to the therapeutic species comprises a Diels-Alder cyclo-addition reaction product. Additionally, in some embodiments, the nanoparticle is a magnetic nanoparticle.
US11559491B2 Oral compositions and the preparation methods thereof
The present invention relates to a process for preparing a solid composition comprising at least one active ingredient and at least one excipient comprising: i) mixing said at least one active ingredient and said at least one excipient in a granulator to obtain wet granules; ii) spreading wet granules on a tray and let stand for 2 to 24 hours between 15 and 25° C.; iii) compressing granules obtained after step ii) with a tablet press; and iv) collecting the solid composition. The invention further relates a solid composition obtained by such process.
US11559489B2 Tuning of release kinetics in hydrogels
The present disclosure is directed to methods for tuning the release profile of a biologic disposed in a hydrogel. Parameters that can be used for the tuning include a molar ratio of a nucleophilic group to an electrophilic group, the number of the nucleophilic groups in the first precursor, the number of the electrophilic groups in the second precursor, the molecular weight of the first precursor, the molecular weight of the second precursor, a weight ratio of the biologic and excipient to the hydrogel, a weight percentage of the biologic in a solid state formulation, and a ratio of surface area to volume of the hydrogel. The methods described herein allow the formation of hydrogel with different release profiles suitable for different therapeutic applications.
US11559487B2 Drug loaded nanoresin particles
The present invention relates to nano-resin particles that are suitable for pharmaceutical use and their use in the pharmaceutical field. The present invention provides nano-sized resin particles having a particle size distribution characterized in that D90 value is between 200 nanometers to 900 nanometer and D10 value is not less than 50 nanometers, wherein the nano-resin particles are in pure form and safe for pharmaceutical use. The present invention further relates to pharmaceutical compositions comprising these purified nano-resin particles and their use in the treatment of diseases.The present invention further provides a process for preparing purified, nano-sized resin particles that are suitable for pharmaceutical use, the process comprising steps of: (i) washing an ion exchange resin and suspending in an aqueous liquid, (ii) subjecting the suspension of (i) to wet milling for a period such that the particles have a particle size distribution characterized in that the D90 value is between 200 nanometers to 900 nanometers and D10 value is not less than 50 nanometers, (iii) subjecting the suspension of (ii) to purification to remove impurities, (iv) drying the purified suspension to obtain nano-resin particles in the form of dry powder.
US11559483B2 Nasal foam via cribriform plate for medication delivery to the brain and/or body and for nasal moisturization and hygiene
Methods and compositions for delivering medicine and other substances to the brain and the body via the cribriform plate using foamable compositions are described. Methods and compositions for improving nasal hygiene and moisturizing the nasal cavity using foamable compositions are also described.
US11559481B2 Methods of intravenous administration of glyburide
The present disclosure is drawn to a method of treating a patient in need of treatment, comprising identifying a patient in need of treatment for stroke, traumatic brain injury, spinal cord injury, myocardial infarction, shock, organ ischemia, ventricular arrhythmias, ischemic injury, or hypoxia/ischemia; administering a bolus of glyburide to the patient; and administering a continuous infusion of glyburide to the patient at from about 15 μg/hr and about 300 μg/hr, wherein the continuous infusion glyburide is administered for a period of time more than about 20 hours.
US11559480B2 Compositions for sensitive skin
Disclosed are compositions and methods for their use that include a combination of escin, Ruscus aculeatus root extract, ammonium glycyrrhizate, Centella asiatica extract, hydrolyzed yeast protein, and Calendula officinalis flower extract.
US11559477B2 Preparation method and use of artificial exosome complex
A preparation method and use of an artificial exosome complex are provided. Raw materials for preparing the artificial exosome complex include linear polyethyleneimine (PEI) and hyaluronic acid (HA). The linear PEI can be obtained through the HA-PEI preparation process of the present disclosure, and most PEI is branched currently. According to the HA-PEI preparation method, HA-PEI with a specific molecular weight can be quantitatively prepared. The preparation process involves controllable operation steps, and thus can be used for large-scale industrial production. The prepared HA-PEI can promote the absorption of an encapsulated active substance by deep skin cells through the ligand activity of HA and the membrane permeability of linear PEI.
US11559476B2 Hydrogel and method for preparing the same
The present application provides a method for preparing a hydrogel and the obtained hydrogel. The method including: forming a first part by mixing a first single-stranded nucleotide with a first liposome, and forming a second part by mixing a second single-stranded nucleotide with a second liposome, wherein the first single-stranded nucleotide and the second single-stranded nucleotide have complementary sticky ends; forming a hydrogel by mixing the first part and the second part.
US11559474B2 Hair lightening compositions and methods of use
The present disclosure relates to hair care compositions such as hair treatment compositions and hair lightening compositions, methods for treating hair (e.g., lightening hair), and to kits comprising the compositions. The components of the hair treatment compositions may be included in hair lightening compositions and used to lighten and/or color hair. The hair treatment compositions typically include: (a) one or more polycarboxylic acids, and/or a salt thereof; (b) one or more amino acids, and/or a salt thereof; and optionally (c) one or more cationic conditioning agents. The hair lightening compositions further include (d) one or more bleaching agents.
US11559473B2 Semisolid oral dispersions comprising active agents
Semisolid oral dispersions for improving the health and/or appearance of the oral cavity. The semisolid oral dispersions include hydrophilic active agent particles in hydrophobic phase. The hydrophilic active agent particles can include bleaching agents, antimicrobial agents, anticalculus agents, and/or combinations thereof. The hydrophilic active agent particle can have a solubility in water of at least about 20 parts, by weight of the particles, in about 100 parts, by weight, of water.
US11559469B2 Systems and methods for controlling the process of compounding admixtures
A compounding apparatus for mixing at least two materials into an admixture can include a processor and software configured to select a non-universal ingredient for substitution as a temporary universal ingredient to be used as a buffer when an original universal ingredient buffer is not available. The processor and software can also include an auto adjust feature to correct for tube wear and other factors creating non-compliant final bag fills. The processor and software can also include a disable station designation feature that allows for disabling a problem station and diverting operation from the designated disabled station to a substitute station. Such operation can ensure continued production of the compounding apparatus.
US11559465B2 Passive temperature controlled container
The disclosed technology includes a passive temperature controlled container for passively maintaining a specified temperature range in a storage chamber of the container for a predetermined amount of time. The passive temperature controlled container may be configured to have an inner PCM layer and an outer PCM layer, with an air chamber layer between the two PCM layers to allow for the free movement of air around all six sides of the container.
US11559464B2 Sealer-less plasma bottle and top for same
A top for a plasma storage container includes a top body that defines the structure of the top and seals an opening of the plasma storage container. The top also includes a first opening and a vent opening extending through the top body. A septum is located at least partially within the first opening and includes an aperture therethrough. The septum allows a blunt cannula to pass through the aperture to access the interior of the plasma storage container. The top also includes a hydrophobic membrane located on underside of the top body. The membrane covers the vent opening and allows air to vent through the vent opening during plasma collection.
US11559460B2 Compression device
A compression device has a main body and a wrap. The main body has an air pump and a valve assembly. The valve assembly has a manifold, multiple first valves, and multiple air connectors. The manifold connects the air pump and the first valves. The air connectors are connected to the first valves respectively. The wrap is used for wrapping a human limb and has an air bag. The air bag has multiple pockets. The pockets are isolated from each other and connected to the air connectors respectively. Thus, each pocket can compress a part of the human limb independently. With the independent pockets, the compression device may compress a specified part of the human limb rather than the whole wrapped human limb. Moreover, with the pockets independently compressing and relaxing, the wrapped human limb may experience a massage, which helps the wrapped human limb to relax and recover.
US11559452B1 Powered managed therapeutic support surface system for the treatment of pressure injuries
A pressure injuries therapeutic support surface is illustrated. The surface comprises an integrated system designed for a concurrent physical and psychoneuroimmunological approach over a user, wherein the system comprises one or a plurality of independent fluid-filled main chambers, made of waterproof, flexible, extendable, and elastic material and at least two accessory chambers connected to each main chamber with at least with two free-flow conduits. The system is managed through a powered mechatronic array with its own hardware and software based on microcontrollers for the simultaneous operation of specific multidisciplinary devices.
US11559445B2 Support devices including movable leg segments and methods for operating the same
A support device includes a wheel, a base member, a leg coupled to the wheel and the base member, the leg including an upper leg segment, a lower leg segment positioned below the upper leg segment, a joint positioned between the upper leg segment and the lower leg segment, the joint including a cam defining a non-circular perimeter, and an actuator coupled to one of the upper leg segment and the lower leg segment, the actuator including an engagement member that is engaged with the non-circular perimeter of the of the cam of the joint, where the actuator selectively moves the engagement member to move the cam and the upper leg segment and the lower leg segment about the joint.
US11559442B2 Patient transport apparatus with controlled auxiliary wheel deployment
A patient transport apparatus transports a patient over a floor surface. The patient transport apparatus comprises a support structure and support wheels coupled to the support structure. An auxiliary wheel is coupled to the support structure to influence motion of the patient transport apparatus over the floor surface to assist users. An actuator is operatively coupled to the auxiliary wheel and operable to move the auxiliary wheel relative to the support structure from a retracted position to a deployed position. A user interface sensor is operatively connected to the actuator and configured to generate signals responsive to the user touching the user interface. A controller is operatively coupled to the user interface sensor and the actuator to operate the actuator in response to detection of signals.
US11559441B2 Method for manufacturing a wound dressing and a wound dressing
A method for manufacturing a wound dressing having a substrate, and a wound dressing manufactured by such a method are described. The method has a step of providing a sacrificial layer of material to be perforated by means of a hot pin perforator, in order to remove any molten residues on the heated pins of the hot pin perforator, before the same pins are used to make holes in the substrate. The presented method is cost effective, robust and reduces the risk of contaminating substances being embedded in the substrate during the hole making process.
US11559440B2 Fiber materials with improved properties for use in wound treatment
Disclosed are materials comprising a fiber material and an agent having at least one having improved tensile strength, in particular wet tensile strength, vis-à-vis fiber materials known from the art. While these fiber materials may be of use in various fields, in particular household products, hygiene products and the like, these fiber materials are of particular use in wound treatment. Also disclosed is a method for producing these materials.
US11559439B2 Wound closure device
A wound dressing for use in the application of negative pressure to a wound, comprising a support member and a cover member positionable over the wound in use. The support member can have a first support element having a first portion aligned with a first axis and a body portion coupled with and extending away from the first portion, and a second support element having a first portion aligned with the first axis and a body portion coupled with and extending away from the first portion of the second support element. At least the body portion of each of the first support element and the second support element can be independently rotatable about the first axis. The support member can support at least a middle portion of the cover member above a surface of the wound so as to define a space between the wound cover and the wound.
US11559438B2 Integrated sensor enabled wound monitoring and/or therapy dressings and systems
A wound monitoring and/or therapy system can include a substantially stretchable substrate supporting a plurality of electronic components, including sensors, and a plurality of electronic connections that connect at least some of the electronic components. The electronic components can also include a circuit board supporting at least one controller configured to control at least some of the sensors, the circuit board configured to operate without failure when the substrate is flexed as a result of strain. A calibration track can be positioned on the substrate and connected to a monitoring circuit configured to measure a change in resistance of the calibration track indicative of resistance change of at least some of the plurality of electronic connections. The system can include a controller with a circuit board supporting a plurality of electrical components and an antenna configured to communicate with the substrate, the antenna at least partially enclosing the circuit board.
US11559437B2 Multi-layered wound dressing and method of manufacture
A multi-layered wound dressing including a fibrous absorbent layer for absorbing exudate from a wound site. The wound dressing also includes a support layer configured to reduce shrinkage of at least a portion of the wound dressing.
US11559436B2 Bi-radial patient interface
A patient interface for an ophthalmic system can include an attachment portion, configured to attach the patient interface to a distal end of the ophthalmic system; a contact portion, configured to dock the patient interface to an eye; and a contact element, coupled to the contact portion, configured to contact a surface of a cornea of the eye as part of the docking of the patient interface to the eye, and having a central portion with a central radius of curvature Rc and a peripheral portion with a peripheral radius of curvature Rp, wherein Rc is smaller than Rp.
US11559435B2 Systems and methods for femtosecond laser ophthalmic surgery docking
The present disclosure provides a system for femtosecond ophthalmic surgery in which a measuring device and a camera generate data that is processed and used to create an enhanced pictorial representation based on the actual positions of the suction ring and the eye. The pictorial representation may include a graphic relating to ophthalmic surgery, such as for a flap or an incision. The disclosure further provides a method for docking a suction ring in femtosecond laser ophthalmic surgery, which includes observing and generating data relating to the position of the suction ring, generating data relating to a pictorial representation of the suction ring and the eye, processing the data relating to the observed position and the pictorial representation to generate an enhanced pictorial representation, and presenting it during surgery. The pictorial representation may include a graphic relating to ophthalmic surgery, such as for a flap or an incision.
US11559433B2 Laser induced collagen crosslinking in tissue
The presently disclosed subject matter provides techniques for inducing collagen cross-linking in human tissue, such as cartilage, by inducing ionization of the water contained in the tissue to produce free radicals that induce chemical cross-linking in the human tissue. In an embodiment, a femtosecond laser operates at sufficiently low laser pulse energy to avoid optical breakdown of the tissue being treated. In an embodiment, the femtosecond laser operates in the infrared frequency range.
US11559430B2 Glaucoma stent and methods thereof for glaucoma treatment
The invention relates generally to medical devices and methods for reducing the intraocular pressure in an animal eye and, more particularly, to stent type devices for permitting aqueous outflow from the eye's anterior chamber and associated methods thereof for the treatment of glaucoma. Some aspects provide a self-trephining glaucoma stent and methods thereof which advantageously allow for a “one-step” procedure in which the incision and placement of the stent are accomplished by a single device and operation. This desirably allows for a faster, safer, and less expensive surgical procedure.
US11559426B2 System including a skin-engageable element of a medical appliance
A system for preserving functionality of a skin-engageable element for attachment to a skin portion of a user during storage including a skin-engageable element and a protective element having discrete portions projecting therefrom. The discrete portions are adapted to engage with through-going passages in an adhesive layer of the skin-engageable element, and ensure that the passages are open and passable when the protective element is removed before use of the skin-engageable element. A protective element attachable to a proximal adhesive side of a skin-engageable element for attachment to a skin portion of a user is also disclosed.
US11559425B2 Ostomy appliance
An ostomy appliance including: first and second walls connected to each other at or near their peripheries, the first wall having a stoma-receiving opening; a connection member connected to the first wall for attaching the appliance to a user; a waste collecting chamber defined by the first and second walls for receiving waste and/or gas from the stoma-receiving opening; a further chamber defined by at least third and fourth walls which are connected to each other; a gas opening provided in either or both of the third or fourth walls for permitting waste gases to pass therethrough from the waste collecting chamber; a gas vent for permitting gases in the further chamber to escape to atmosphere; and wherein movement of the first and second walls away from each other, from waste or gases entering the waste collecting chamber, increases or at least maintains the volume of the further chamber.
US11559423B2 Medical appliance system, monitor device, and method of monitoring a medical appliance
A monitor device for an ostomy system comprising an ostomy appliance with a base plate and a method of monitoring an ostomy appliance is disclosed. The monitor device comprises a processor configured to apply a processing scheme; memory; a first interface connected to the processor and the memory, the first interface configured for collecting ostomy data from the base plate coupled to the first interface; and a second interface connected to the processor, wherein to apply a processing scheme comprises: obtain first parameter data, second parameter data, and third parameter data based on the ostomy data; and determine an operating state of the base plate of the ostomy appliance based on the first parameter data, the second parameter data and the third parameter data, wherein the operating state is indicative of a degree of radial erosion of the base plate and/or acute leakage risk for the ostomy appliance, wherein the monitor device is configured to, in accordance with a determination that the operating state is a first operating state, transmit a first monitor signal comprising monitor data indicative of the first operating state of the base plate via the second interface; and in accordance with a determination that the operating state is a second operating state, transmit a second monitor signal comprising monitor data indicative of the second operating state of the base plate via the second interface.
US11559421B2 Protective dressing with reusable phase-change material cooling insert
A protective dressing includes an outer dressing and an adhesive layer. The outer dressing includes an opening and a cavity sized to receive a phase-change material (PCM) insert inserted through the opening. The adhesive layer is configured to adhere to a patient's skin surrounding an anatomic site. When adhered to the patient's skin, the PCM insert modifies the patient's skin at the anatomic site. The PCM insert may be removed and replaced with another PCM insert. For example, a warm PCM insert may be replaced with a refrigerated PCM insert. The opening of the outer dressing may be self-sealing. The opening of the outer dressing may be sealed with an upper layer dressing coupled to the PCM cooling insert.
US11559420B2 Personal augmentation suit and method for assisted human motion with back differential assembly
A human motion assistance device has upper back straps and is configured to attach to a user. A leg strap arrangement with lower back straps is configured to attach to the user. A differential assembly is connected between the upper back straps and lower back straps to reduce resistance of the upper torso harness and leg strap arrangement during gait. When crouching or lifting, the differential assembly transfers force to stretch and retract the upper torso harness and leg strap arrangement, which provides human motion assistance. The differential assembly can be implements as an x-bar, lever arm, pulley, gears, or tube. The leg strap arrangement has a knee pad adapted to cover a knee of the user. The knee pad opens along a segment. The upper torso harness has a shoulder strap and buckle. The leg strap arrangement is an elastic material.
US11559419B2 Functional ankle supports with improved movement and comfort
An ankle brace, having a rear-entry ankle cuff adapted to be worn adjacently above lateral and medial malleoli of an ankle, and an open-heel, open-malleoli and open-toe midfoot member extending forwardly and downwardly from the ankle cuff.
US11559418B2 Automatic-sealing balloon-filling catheter system
Valve assemblies for use with expandable devices that are positioned within remote cavities and more particularly relates to the catheters/conduits used to inflate these devices with fluid.
US11559416B2 Portable and hand-held medical device crimper
A crimper includes a first arm that includes a first crimper die that defines a first tapered channel. The crimper also includes a second arm coupled to the first arm at a pivot connection. The second arm includes a second crimper die that defines a second tapered channel. The pivot connection enables the first arm and the second arm to rotate about the pivot connection from an open state to a closed state. The first arm and second arm rotate at an angle relative to one another to allow loading of the expandable medical device into the first tapered channel or the second tapered channel and to allow positioning of the expandable medical device relative to a delivery device. When transitioning, the first tapered channel and the second tapered channel form a chamber that is configured to crimp the expandable medical device from the uncompressed state to the compressed state.
US11559413B2 Anti-migration micropatterned stent coating
An endoprosthesis has an expanded state and a contracted state, the endoprosthesis includes a stent having an inner surface defining a lumen, having an outer surface, and defining a plurality of apertures through the outer surface, wherein the apertures are arranged in a micropattern; and a coating (e.g., polymeric coating) attached to the outer surface of the stent. The coating includes a base and a tissue engagement portion including a second surface facing outwardly from the stent, the tissue engagement portion including a structure that defines a plurality of holes extending inwardly from the second surface toward the base. The holes are arranged in a micropattern. When the endoprosthesis is expanded to the expanded state in a lumen defined by a vessel wall, the structure applies a force that may reduce stent migration by creating an interlock between the vessel wall and the endoprosthesis.
US11559411B2 Prosthesis and prosthetic foot adapter
A prosthesis having a prosthetic foot with a forefoot area and a heel area, a prosthetic lower leg, and a prosthetic foot adapter for arranging the prosthetic foot on the prosthetic lower leg. The prosthetic foot adapter includes an upper part for fixing it to the prosthetic lower leg such that it is torque-proof in relation to a sagittal plane, a lower part for fixing it to the prosthetic foot such that it is torque-proof in relation to a sagittal plane, and a resistance element. The upper part can be swivelled on the lower part about a swivel axis against a restoring force exerted by the restoring element, the swivel axis extending from the heel area to the forefoot area.
US11559409B2 Expandable implant with deflectable sequence of segments
An implant (100, 200, 300, 400) includes a base (10), and a sequence of at least two segments including a first segment (12) and a last segment (14). The first segment (12) is pivotally linked to base (10). Adjacent segments are interconnected at pivotal connections (18). A bolt (20) has a threaded shaft (22) and a head (24). The threaded shaft (22) is engaged in a threaded channel (26) of the base (10) so that rotation of the bolt (20) about a central axis of the threaded shaft (22) varies a degree of overlap between the base (10) and the bolt (20). The last segment (14) and the head (24) define therebetween a spherical bearing (28). Rotation of bolt (20) thus varies a distance between spherical hearing (28) and hinge pin (16), thereby causing deflection of the sequence of segments.
US11559405B2 Robotic shoulder fracture management
A method of repairing a fractured humerus may include implanting a prosthetic humeral stem into a humeral canal of the fractured humerus. First and second tuberosities of the fractured humerus may be robotically machined to include first and second implant-facing surfaces that are substantially negatives of first and second surface portions of the proximal end of the prosthetic humeral stem. The first and second tuberosities may be machined so that the first and second tuberosities have first and second interlocking surfaces shaped to interlock with each other. During implantation, the first and second implant-facing surfaces are in contact with the first and second surface portions of the proximal end of the prosthetic humeral stem, and the first interlocking surface interlocks with the second interlocking surface.
US11559404B2 Acetabular surgical implant for segmental pelvic defect and methods of use and manufacture
A method of implanting a medical device including forming a tunnel at least partially through a patient's bone, placing the medical device on the bone so that a stress-diffusion element (i.e., a stem) extending from the medical device at least partially extends into the tunnel, and securing the medical device to the bone. The medical device includes a hemispherical cup having a bone-abutment exterior surface, an interior surface defining a cavity, a circumferential rim extending between the exterior surface and the interior surface, and at least one aperture extending between the exterior surface and the interior surface. The stress-diffusion element is formed to extend from and be oriented with respect to the cup based on whether the surgical implant is to be used on a left side or right side of the patient for reconstruction of the segmental acetabular defect.
US11559402B2 Soft glenoid awning and related repair procedures
Systems and methods for opposing abnormal motion of an adjacent bone are provided. One exemplary embodiment of a surgical method includes delivering and securing a bone barrier to a bone bed of a glenoid such that at least a portion of the bone barrier extends laterally beyond the bone bed and can oppose, prevent, and/or reduce abnormal motion of an adjacent bone (e.g., a humeral head). The bone barrier can be secured along a periphery of a glenoid of a shoulder. More particularly, the bone barrier can be placed and secured such that at least a portion of the bone barrier extends laterally over the glenoid and can oppose abnormal motion of the humeral head. In some embodiments at least one suture anchor and suture can secure the bone barrier to the bone bed.
US11559398B2 Delivery systems with telescoping capsules for deploying prosthetic heart valve devices and associated methods
Delivery systems with telescoping capsules for delivering prosthetic heart valve devices and associated methods are disclosed herein. A delivery system configured in accordance with embodiments of the present technology can include, for example, a delivery capsule having a first housing, a second housing slidably disposed within a portion of the first housing, and a prosthetic device constrained within the first and second housings. The delivery capsule can further include first and second chamber defined in part by the first and second housings. During deployment, fluid is delivered to the first chamber to move the first housing distally over the second housing, thereby releasing a portion of the prosthetic device. Subsequently, fluid is delivered to the second chamber such that the first and second housings move together in the distal direction to release a second portion of the prosthetic device.
US11559397B2 Heart valve repair
In some examples, a delivery device includes a handle that includes a control member, an elongate body, a plurality of arms extending from a distal portion of the elongate body to a distal collar configured to releasably couple to an annuloplasty device. The plurality of arms is operatively coupled to the control member and configured to position the annuloplasty device at a target site in a patient. The delivery device further comprises a plurality of anchors configured to secure the annuloplasty device to tissue at the target site, each respective anchor of the plurality of anchors deployable from a respective arm of the plurality of arms.
US11559396B2 Transcatheter valve prosthesis for blood vessel
A transcatheter temporary valve prosthesis for blood vessel comprising an expandable support structure (5″), a valve (7), a filter (12) and a conveyor (6); said support structure (5″) forming a tubular shape when expanded, with a distal and a proximal end, said valve (7) being located at said distal end and said conveyor (6) extending within said support structure (5), from said proximal to said distal end and including a central passage that is adapted to act as an introducer for other devices.
US11559394B2 Prosthetic valves, valve leaflets and related methods
Examples herein include prosthetic valves, valve leaflets and related methods. In an example, a prosthetic valve is included having a plurality of leaflets. The leaflets can each have a root portion and an edge portion substantially opposite the root portion and movable relative to the root portion. The leaflets can include a fibrous matrix including polymeric fibers having an average diameter of about 10 nanometers to about 10 micrometers. A coating can surround the polymeric fibers within the fibrous matrix. The coating can have a thickness of about 3 to about 30 nanometers. The coating can be formed of a material selected from the group consisting of a metal oxide, a nitride, a carbide, a sulfide, or fluoride. In an example, a method of making a valve is included. Other examples are also included herein.
US11559387B2 Substrate with rotatable struts for medical device
A medical device comprises a substrate (10) defining a major surface (9) defining a plane, including a plurality of first struts (14) along a first direction interconnected with a plurality of second struts (12) extending along a second direction not parallel with the first direction, wherein widths (11) of the second struts as measured along the major surface are larger than thicknesses of the second struts as measured perpendicular to the major surface such that when the substrate is stretched in the first direction, intermediate sections (15) of the second struts (12) rotate relative to the first struts (14) and the intermediate sections of the second struts bend out of the plane of the major surface. The medical device is operable to extend and/or retract elements suitable for a particular purpose. The elements are extended and/or retracted in response to a stress applied by way of stretching and/or retracting the device, among other methods. The elements may remain extended and/or retracted or may recoil back to an initial position upon the removal of the force. In various embodiments, the elements are used to treat or deliver treatment to a target site within a body.
US11559385B2 Device for use with body tissue sphincters
A medical device may include an implantable device for treating a body tissue structure. The implantable device may include a plurality of bodies spaced from adjacent bodies and arranged so as to be configured to extend around an exterior surface of a body tissue structure. The bodies may be configured to apply a static force to the body tissue in a relaxed state and may adjust or move in response to a radially outward force above a threshold level that is acting on one or more of the bodies. The bodies may be pliable and/or made with a pliable material. The bodies may be interconnected via interconnecting regions. One or more of the bodies may be configured to articulate so as to conform to movement of a body tissue structure. A skeletal component may or may not extend through one or more of the plurality of bodies.
US11559382B2 System for treating embolism and associated devices and methods
Systems and methods for the intravascular treatment of clot material within a blood vessel of a human patient are disclosed herein. A method in accordance with embodiments of the present technology can include, for example, positioning a distal portion of a catheter proximate to the clot material within the blood vessel. The method can further include coupling a pressure source to the catheter via a tubing subsystem including a valve or other fluid control device and, while the valve is closed, activating the pressure source to charge a vacuum. The valve can then be opened to apply the vacuum to the catheter to thereby aspirate at least a portion of the clot material from the blood vessel and into the catheter.
US11559378B2 Scanning dental impressions
Systems and methods are provided for scanning a dental impression to obtain a digital model of a patient's dentition as an input to computer aided design (CAD) and computer aided manufacturing (CAM) methods for producing dental prostheses.
US11559377B2 Augmented reality enhancements for dental practitioners
An image of a dental arch comprising a preparation tooth is generated by an image capture device associated with an augmented reality (AR) display. The image of the dental arch is registered to previous image data associated with the dental arch. A visual overlay associated with a dental prosthetic to be placed on the preparation tooth is generated based on the registering of the image of the dental arch to the previous image data associated with the dental arch. The visual overlay is output to the AR display, wherein the visual overlay is superimposed over a view of the preparation tooth on the AR display.
US11559376B2 Screw-retained abutment with off-axis feature and methods of making and using same
An abutment is provided with a screw access hole and a slot in its sidewall adapted to allow a driver to access a screw in the screw access hole at an angle relative to a longitudinal axis of the screw. The abutment may include a screw seat and may be connected to an implant via a screw in the screw seat. A prosthesis, which may include a driver access channel that has a diameter less than the outer diameter of the drive portion of the screw, may be placed over the abutment. Methods of making a dental prosthesis and methods of attaching and removing the dental prosthesis from the implant are also disclosed.
US11559375B2 Diamond dental teeth formed by using laser energy
A dental implant has an implant body made of diamond material, the implant body being provided with a bore hole that has at least one lateral dimension and a depth dimension, the lateral dimension and the depth dimension being mm sized. The bore hole is substantially formed by laser light being directed at the implant body to form said bore hole by softening said diamond material at an intended location of said bore hole. The bore hole is further defined by utilizing at least one metallic drilling tool to remove more of the diamond material after initial formation of the bore hole by said laser light. Preferably, the drilling tool has a cone shaped drilling head or a rectangular drilling head.
US11559374B2 Release agent receptacle
The present disclosure includes method, system, apparatus, and indicator embodiments. One apparatus includes an appliance for placement over one or more teeth and a release agent receptacle including an outer portion provided on appliance surface, an inner portion provided within the outer portion, and one or more apertures formed in the outer portion.
US11559363B2 Controller controlled instrument preload mechanism
A computer-assisted teleoperated system includes a pre-load assembly in an instrument manipulator that is under the control of a controller. The controller can automatically cause the preload assembly to engage and disengage a preload. A surgical apparatus includes an instrument manipulator assembly and a sterile adapter assembly. The sterile adapter assembly is mounted in the distal face of the instrument manipulator assembly. When the preload assembly configures the instrument manipulator assembly to apply a preload force on the sterile adapter assembly, the sterile adapter assembly is removable from the distal face of the instrument manipulator. The sterile adapter assembly includes a mechanical sterile adapter assembly removal lockout and a mechanical instrument removal lockout.
US11559356B2 Systems and methods for planning and performing image free implant revision surgery
Systems and methods for planning and performing image free implant revision surgery are discussed. For example, a method for generating a revision plan can include collecting pre-defined parameters characterizing a target bone, generating a 3D model, collecting a plurality of surface points, and generating a reshaped 3D model. Generating the 3D model of the target bone can be based on a first portion of the pre-defined parameters. Generating the reshaped 3D model can be done based on the plurality of surface points collected from a portion of the surface of the target bone.
US11559354B2 System and method for microablation of tissue
The present invention generally relates to the field of laser treatment of tissue, and particularly, to a system and method for creating microablated channels in skin. The present invention is more particularly directed to treating subsurface tissue through the created channels.
US11559353B1 Ablative skin resurfacing with topical radiation block
The present invention uses one or more radiation-emitting devices in combination with a topical radiation block to ablate the skin and remove topographic variations in the skin surface. The energy pathway may be guided by a computer. The device might also include a treatment plate or window to be placed against the skin in order to flatten the skin surface during treatment. The purpose of the topical radiation block is to manage the areas to which the radiation is applied to the skin by allowing the radiation to reach some portions of the skin, while limiting or preventing the radiation from reaching other portions of the skin. In the case of atrophic scarring, for example, the block may be deposited selectively into the atrophic indentations, such that the block limits or prevents the radiation from reaching (and thereby ablating) the indentations, but allows the radiation to reach (and thereby ablate) the surrounding skin tissue. By ablating only the surrounding tissue, the z of the surrounding tissue is reduced, eventually minimizing or eliminating differences in the skin's topography between the indentations and the surrounding tissue. In the case of hypertrophic scarring, the block may be applied selectively to the surrounding tissue, such that the block limits or prevents the radiation from reaching (and thereby ablating) the scars, but allows the radiation to reach (and thereby ablate) the scars. By ablating only the scars, the z of the scars is reduced, eventually minimizing or eliminating differences in the skin's topography between the scars and the surrounding tissue.
US11559351B2 Temperature sensor structure in printed-circuit-board (PCB) wall of radiofrequency (RF) ablation catheter tip electrode
A tip electrode of a catheter includes an outer wall and a temperature sensor assembly. The outer wall includes a thermally conductive multilayer printed circuit board (TCM-PCB) that includes a void. The temperature sensor assembly, which is fitted in the void of the TCM-PCB, includes a temperature sensor, one or more thermally insulating layers that surround a volume of the temperature sensor excluding one facet of the volume, and a heat conductive layer covering the excluded facet.
US11559340B2 Bone repair system and method
A bone repair system and method for percutaneously fixing a first bone segment to a second bone segment, such as rib bone segments, in a body of a patient include drilling a first hole through the first bone segment and a second hole through the second bone segment, and feeding a first tether through the first hole and a second tether through the second hole, each tether having a proximal end and a distal end. The first and second tether distal ends are withdrawn from the body while the first and second tether proximal ends have not passed through the first and second bone segments, respectively. A reinforcing member, such as a bone plate, having first and second openings, is passed onto the first and second tether distal ends, and the reinforcing member is pulled into engagement with the first and second bone segments guided by the tethers. The reinforcing member is secured to the first bone segment with a first fastener assembly through the first hole and the first opening and to the second bone segment with a second fastener assembly through the second hole and the second opening to fix the first bone segment to the second bone segment.
US11559338B1 Spinal implant system and method
An instrument includes an outer sleeve defining a passageway and extending along an axis between proximal and distal ends. A knob sleeve is positioned in the passageway and defines a bore and a sleeve cavity. A latch is positioned in the sleeve cavity. A shaft is positioned in the bore. An inner sleeve is positioned between the knob sleeve and the shaft. A proximal end of the inner sleeve defines a notch. The knob sleeve is movable relative to the outer sleeve to move the instrument between a first orientation in which the latch is positioned in the notch and the inner sleeve is prevented from translating along the axis and a second orientation in which the latch is spaced apart from the notch and the inner sleeve is translatable along the axis. Systems, implants and methods are disclosed.
US11559334B2 Spinal implant system and methods of use
A bone fastener comprises a first member defining an implant cavity and a plurality of adjacent grooves. A first band is configured for disposal within the grooves. A second band is configured for disposal within the grooves. A second member is configured to penetrate tissue and includes a head engageable with the first band to provisionally connect the members. The second band is moveable for disposal adjacent the first band to fix connection of the members. Implants, systems, instruments and methods are disclosed.
US11559320B2 Inverting thrombectomy apparatuses and methods
Rolling tractor tube mechanical thrombectomy apparatuses that may be deployed from out of a catheter in situ are described herein. These apparatuses may be delivered out of a catheter from a collapsed delivery configuration within the catheter to a deployed configuration out of the catheter, in which the same catheter is re-inserted between a tubular tractor and an elongate puller. In particular, any of these methods and apparatuses may be adapted to work with a tractor tube having an open end that is biased open, including using an annular bias.
US11559319B2 Unfocused electrohydraulic lithotripter
Electrohydraulic lithotripters comprising a plurality of electrohydraulic probes are disclosed. Each probe of the plurality of probes comprise a first electrode and a second electrode positioned at a distal end of the probe such that when the probe is discharged, an electric arc between the first electrode and the second electrode produces a shockwave that radiates from the distal end of the probe. A first probe and a second probe of the plurality of probes may be configured to discharge simultaneously or sequentially.
US11559311B2 Method of applying hemostatic or tissue healing agent to wet surfaces
A device for applying a tissue healing agent includes an insertion member extending longitudinally from a proximal end to a distal end and including a channel extending therethrough, a delivery element including a first surface and a second surface opposing one another, the delivery element movable between a closed configuration, in which the delivery element is compressed to be received within the channel, and an open configuration, in which the delivery element is substantially planar, and a first tissue healing agent formed in a sheet configuration and disposed on the first surface of the delivery element.
US11559310B2 Aortic occlusion balloon apparatus, system and method of making
The disclosure sets forth various exemplary embodiments of systems, methods, and/or medical apparatuses including but not limited to: a sheath; and a balloon disposed at a working distal end of the sheath. According to one example embodiment the medical device can include where the sheath can include woven wire reinforcing axial and longitudinal strength, side holes, a one direction distal valve, and can include an inflator. According to one example embodiment the medical device can include where the sheath can include a narrow cross-section of, e.g., 7-8 Fr and balloon of length of, e.g., 12 cm.
US11559305B2 Stapling systems and methods for surgical devices and end effectors
Embodiments include an end effector including an anvil, the anvil having an anvil face, an anvil blade channel defined by the anvil face, a first pocket row of first row staple pockets, a second pocket row of second row staple pockets, a third pocket row of third row staple pockets, a fourth pocket row of fourth row staple pockets, a fifth pocket row of fifth row staple pockets, a sixth pocket row of sixth row staple pockets, a cartridge having a cartridge face defining a cartridge blade channel, the cartridge being configured to retain a plurality of staples, and a blade, the blade having a cutting edge, where the blade is movable from a first position at a distal end of the cartridge to a second position at a proximal end of the cartridge.
US11559294B2 Devices and methods for targeted delivery of a substance
A device for applying a bubble of a substance to a tissue surface, the device comprising a cannula, a distal tip at the distal end portion of the cannula, the distal tip having a bubble support surface and an exit port extending through the bubble support surface, an expansion fluid passageway extending through the cannula to the exit port, a source of an expansion fluid and an actuator therefor. In some arrangements, the distal tip can be configured to support a layer of the substance thereon over the distal port and the device can be configured such that the advancement of the expansion fluid from the fluid source through the exit port causes at least one bubble of the substance to form on the distal tip, wherein the at least a portion of the bubble can be transferred to the tissue surface to treat a defect on the tissue surface.
US11559293B1 Apparatus for facilitating access to abdominal cavity of a patient and removing larger cancerous tumors
An apparatus and method is provided for accessing an abdominal cavity of a patient via the anus for any number of surgical operations, e.g., colon cancer, appendectomy, lymph node biopsy, etc. The apparatus includes a tubular body that extends to an open end having a plurality of holes. The tubular body is inserted into the intestine of the patient, and a clamp is inserted through the tubular body of the apparatus and into the intestine. The clamp and the attached intestine is then pulled into the tubular body, so that the intestine can then be cut. The clamp and the adjacent intestine are then moved out of the tubular body so that the surgery may be performed through the intestine. The cut ends of the intestine can then be reattached (e.g., stapled, sutured, etc.) following completion of the surgery.
US11559292B2 Handle for a surgical tool
A handle for a surgical tool including a shaft having a proximal end and a distal end with a gripping handle affixed to the proximal end of the shaft. A bushing is attached to the distal end of the shaft, the bushing including a plurality of flexible members circumferentially spaced apart. The handle further includes a sleeve circumscribing the shaft and the bushing. The sleeve is moveable between a first position substantially covering an entirety of the bushing and a second position spaced from a most distal end of the bushing.
US11559291B2 Cytology sampling system and method of utilizing the same
A cytology sampling system includes a catheter tube and a cytology tool. The catheter tube has open proximal and distal ends. The cytology tool is insertable through the catheter tube and includes a flexible shaft, a brush, and a position sensor. The flexible shaft defines proximal and distal ends thereof. The brush is coupled to the distal end of the flexible shaft. The brush includes a plurality of brush shafts. Each brush shaft has bristles disposed along a portion of a length thereof. The bristles are coupled to and extend radially away from an outer surface of each of the brush shafts. The bristles are configured to collect cell samples from targeted tissue of a patient. The position sensor provides an indication of the location of the position sensor within a luminal structure. The system may include a positioning assembly for placing the distal end of the catheter tube adjacent the target tissue.
US11559286B2 Ultrasound diagnostic apparatus and control program thereof for detecting the three dimensional size of a low echo region
An ultrasound diagnostic apparatus and a control program for an ultrasound diagnostic apparatus. According to an embodiment, the ultrasound diagnostic apparatus includes an ultrasound probe that transmits and receives ultrasound waves to and from a subject in three dimensional space, a position sensor, and a processor. The processor is configured to determine whether or not a first region and a second region configure the same three dimensional region across a first scanning surface and a second scanning surface. The processor is configured to perform, based on the determining result, processing to obtain information representing the size of the three dimensional region in a direction intersecting the first scanning surface and the second scanning surface. The processor is configured to perform control for notifying the information.
US11559284B2 Ultrasound imaging apparatus with image selector
An ultrasound imaging system includes a cine buffer in which image frames produced during an examination are stored. A processor is programmed to select one or more image frames from the cine buffer for presentation to an operator for approval and inclusion in a patient record or other report. The operator can accept the proposed image frames or can select one or more other image frames from the cine buffer. The processor may select image frames at spaced intervals in the cine buffer for presentation. Alternatively, the processor compares image frames in the cine buffer with one or more target image frames. Image frames that are similar to the target image frames are presented to the operator to confirm. Alternatively, image frames can be selected by the processor that contain a specific feature or that are similar to image frames that were previously selected by the operator when performing a particular type of examination.
US11559276B2 Systems and methods for ultrasound screening
The invention provides an ultrasound system including an ultrasound transducer array and a processor. The ultrasound transducer array comprises a plurality of transducer elements adapted to conform with a subjects body. Further, at least two ultrasound transducer elements of the plurality of transducer elements are adapted to acquire a plurality of ultrasound signals from a region of interest at different orientations relative to said region of interest. The processor is adapted to receive ultrasound signals acquired by the ultrasound transducer array. The processor is further adapted to partition the plurality of ultrasound signals according to a signal depth and, for each ultrasound signal partition, calculate a Doppler power. For each ultrasound signal, the processor identifies a depth of a fetal heartbeat based on the Doppler power of each ultrasound signal partition and identifies a fetal heart region based on the identified fetal heartbeat and a location of the at least two ultrasound transducers.
US11559273B2 Mammography apparatus and program
A mammography apparatus includes a diagnostic image acquisition unit that acquires a diagnostic image in which a calcification as a biopsy target is marked; a scout image acquisition unit that acquires a scout image obtained by imaging a mamma undergoing the biopsy from a specific direction; and a display unit that highlights a calcification (candidate for biological tissue examination) in the scout image which matches at least the marked calcification in the diagnostic image.
US11559272B2 Methods and systems for computed tomography
Methods and systems are provided for cardiac computed tomography imaging. In one embodiment, a method comprises reconstructing an image from projection data acquired during a scan with a reconstruction time determined based on a model relating a timing of an event to be imaged to a heart rate measured during the scan. In this way, the timing of a reconstruction may be consistently applied for a series of reconstructions, thereby inherently registering the reconstructions.
US11559271B2 Method and data processing system for providing decision-supporting data
A method is for providing decision-supporting data. In an embodiment, the method includes receiving photon-counting computed tomography data relating to an examination region; determining a location of a thrombus in the examination region, based on the photon-counting computed tomography data received; generating the decision-supporting data, relating to at least one of the thrombus and a vascular wall in a region of the thrombus, based on the photon-counting computed tomography data received and the location of the thrombus determined; and providing the decision-supporting data generated.
US11559268B2 Low-dose x-ray imaging system
A back illuminated sensor is included as a collector component of a detector for use in intraoral and extraoral 2D and 3D dental radiography, digital tomosynthesis, photon-counting computed tomography, positron emission tomography (PET), and single-photon emission computed tomography (SPECT). The disclosed imaging method includes one or more intraoral or extraoral emitters for emitting a low-dose gamma ray or x-ray beam through an examination area; and one or more intraoral or extraoral detectors for receiving the beam, each detector including a back illuminated sensor. Within the detector, the beam is converted into light and then focused and collected at a photocathode layer without passing through the wiring layer of the back illuminated sensor.
US11559267B2 Ultra-fast scanning x-ray imaging device
Disclosed is a linear array ultra-fast scanning x-ray imaging device. The linear array x-ray imaging device is single photon sensitive, operating in frame output mode and including a pixel array Application Specific Integrated Circuit including the readout pixel array. The ASIC includes digital control logic and sufficient memory to accumulate digital output frames in various modes of operation prior to output from the ASIC, permitting advanced imaging functionalities directly on the ASIC, while maintaining a dynamic range of 16 bits and single photon sensitivity. The effective or secondary frames output from the pixel array ASIC can be tagged with user provided external triggers synchronizing the effective frames to the x-ray beam energy and/or to the movement of the x-ray source or imaged object. This enables dual energy imaging and ultra-fast scanning, without complex and costly conventional photon counting x-ray imaging sensors. The system architecture is simpler and higher performance.
US11559265B2 Systems and methods for adjusting medical device
A method for adjusting a medical device is provided. The method includes obtaining an initial trajectory of a component of the medical device. The initial trajectory of the component includes a plurality of initial positions. For each of the plurality of initial positions, the method further includes determining whether a collision is likely to occur between a subject and the component according to the initial trajectory of the component. In response to the determination that the collision is likely to occur, the method further includes updating the initial trajectory of the component to determine an updated trajectory of the component.
US11559258B2 Stimulation lead with electrodes configured for sensing and stimulation over a partial circumference
A lead body is operable to be implanted proximate a target nerve tissue of a patient. A sensing electrode is configured to sense biopotentials over a first partial circumference of the lead body. A stimulation electrode is configured to deliver stimulation energy over a second partial circumference of the lead body. A signal generator is electrically coupled to the stimulation electrode and a sensing circuit is coupled to the sensing electrode. A processor is operable to apply a stimulation signal to the stimulation electrode via the signal generator and, via the sensing circuit, sense an evoked response to the stimulation signal that propagates along a neural pathway.
US11559257B2 Catheter insert including one or more sensors
In some examples, a device includes a catheter insert elongated body defining a body lumen, the catheter insert elongated body being configured to be at least partially inserted to a catheter lumen defined by a catheter without covering a first fluid opening of the catheter and to form a fluidically tight coupling with the catheter, and one or more sensors positioned on the elongated body. At least one of the one or more sensors are configured to sense a substance of interest. The catheter insert elongated body includes a material that is a substantially non-permeable to the substance of interest.
US11559255B1 Head-mounted physiological signal monitoring system, devices and methods
Earphone apparatus includes dry electrophysiological electrodes and, optionally, other physiological and/or environmental sensors to measure signals such as ECG from the head of a subject. Methods of use of such apparatus to provide fitness, health, or other measured or derived, estimated, or predicted metrics are also disclosed.
US11559253B2 Wearable physical-activity measurement system for balancing physical-activity energy expenditure and basal metabolic rate to food energy intake by adjusting measured portions of food ingredients
An energy balancing system scales portion sizes of user-selected meal recipes to control a digital scale to prompt the user to measure scaled quantities of meal ingredients to prepare scaled meals. Physical activity tracking devices provide data to generate physical activity energy expenditures for energy burned by physical activity. The physical activity energy is added to a basal metabolic rate of energy expenditure that is a function of sex, weight, height, and age. The total energy expended are scaled down for a weight-loss goal to obtain the total recommended energy. A recipe portion-size optimizer adjusts scaling factors for each recipe so that the total recommended energy is met by the scaled meals. Amounts of nutrients for the recipes can also be scaled by the scaling factors to match recommended nutrient amounts when the meal recipe optimizer generates the scaling factors using an over-determined linear system optimizer.
US11559245B2 Apparatus for examining brain injury, method of making and method of using the same
A test apparatus or system for testing impact induced brain trauma a method of making and a method using the same are provided. The system includes a head model, which includes a skull component, a brain component, and a fluid component. The skull component has a wall defining an interior chamber. The brain component includes a gel material and is disposed within the interior chamber. The fluid component is disposed inside the interior chamber. The system may also include a fluid tank fluidly coupled with the skull component and configured to provide the fluid component into the interior chamber. The head model may further include a layer of porous media disposed between the brain component and the interior wall surface of the skull component. The system may include at least one impact element for providing an impact on the head model. The impact is translational or rotational or both.
US11559241B2 Methods and systems for reducing false declarations of arrhythmias
Computer implemented methods and systems are provided that comprise, under control of one or more processors of a medical device, where the one or more processors are configured with specific executable instructions. The methods and systems obtain motion data indicative of at least one of a posture or a respiration cycle; obtain cardiac activity (CA) signals for a series of beats; identify whether a characteristic of interest (COI) from at least a first segment of the CA signals exceeds a COI limit; analyze the motion data to determine whether at least one of the posture or respiration cycle at least in part caused the COI to exceed the COI limit. Based on the analyzing operation, the methods and systems automatically adjust a CA sensing parameter utilized by the medical device to detect R-waves in subsequent CA signals; and detect an arrhythmia based on a presence or absence of one or more of the R-waves in at least a second segment of the CA signals.
US11559239B2 Electronic device including electrically conductive connection member
An electronic device is provided. The electronic device includes a housing, a printed circuit board disposed inside the housing and including a first face and a second face that faces away from the first face, a connection member disposed on the first face and electrically connected to the printed circuit board, a switch member disposed on the first face and at least partially overlaps the connection member when viewed from above the first face, and a button member including an electrically conductive member, and disposed to be capable of operating the switch member. The electrically conductive member is electrically connected to the connection member.
US11559237B1 Robust real-time EEG suppression detection device and method
The present invention relates to a physiological monitor and system, more particularly to an electroencephalogram (EEG) monitor and system, and a method of detecting the presence or occurrence of suppression in the EEG signal. Accurately detecting signal suppression in real-time provides the clinician with the ability to prevent possibly severe, long-term damage to patients as a result of excessive anesthetic or sedative. The present invention provides such a system and method for accurately and automatically detecting suppression in physiological, particularly EEG, signals in real-time and allowing for the administration of treatment or medication to reverse the effects of such situations, or minimize the harm caused. The present invention also allows for the use of closed-loop treatment or drug delivery systems to further automate the process and provide rapid treatment to a patient to reverse or minimize potential harm.
US11559234B2 Portable electrocardiography device
An electrocardiography device is described that can include a main body, an adjustable cap, and a power switch. The main body can include an electrode of a plurality of electrodes configured to acquire electrical signal from a patient. The adjustable cap can include two electrodes of the plurality of electrodes. The adjustable cap can be rotatable around an axis on the main body to orient the plurality of electrodes on different locations on a body of the patient. The power switch can activate the plurality of electrodes to acquire the electrical signal from the patient. Related apparatuses, systems, methods, techniques and articles are also described.
US11559233B2 Nursing machine and wearable working head thereof
Disclosed is a nursing machine that includes a wearable working head and a urine detection circuit. The urine detection circuit includes at least two first urine sensors and at least two second urine sensors that are arranged on the working head. In response to more than one first urine sensor each outputting a liquid detected signal or in response to more than one second urine sensor each outputting the liquid detected signal, the urine detection circuit is configured to output a urine signal. In response to only one first urine sensor or only one second urine sensor outputting the liquid detected signal or in response to only one first urine sensor and only one second urine sensor each outputting the liquid detected signal, the urine detection circuit doesn't output the urine signal.
US11559224B2 Optimization tool for auditory devices
An optimization system for testing a patient's hearing comprises a controller, an ear piece, and a memory. The controller: provides a series of tones to the ear piece; receives feedback from the patient between each tone; generates a data point to be used in an audiogram after receiving each feedback; after each data point is generated, computes a statistical distribution based on the generated data points; identifies an area of the statistical distribution most in need of additional data; and selects a subsequent tone to provide in the series of tones. Each feedback indicates whether the respective tone was detected or not detected, and each data point is based on the respective feedback. Each subsequent tone provided in the series of tones is a tone represented in the area of the statistical distribution most in need of additional data at the time of selection.
US11559223B2 Glucose measuring apparatus and method
Disclosed is a glucose measuring apparatus including a pressure measurer having an elastic part or a pressure sensor, that measures a pressure applied to an object, a film that comprises a first optical waveguide configured to be close to the object, a near infrared ray (NIR) irradiator that irradiates an NIR to the first optical waveguide if the measured pressure is greater than or equal to a preset value, an NIR receiver that receives an attenuated total reflection NIR (ATR-NIR) from the first optical waveguide, and an analyzer that measures a blood glucose level based on the ATR-NIR, wherein the film is an independent module that can be combined with and separated from the glucose measuring apparatus.
US11559221B2 Multi-task progressive networks for patient modeling for medical scans
For training for and performance of patient modeling from surface data in a medical system, a progressive multi-task model is used. Different tasks for scanning are provided, such as landmark estimation and patient pose estimation. One or more features learned for one task are used as fixed or constant features in the other task. This progressive approach based on shared features increases efficiency while avoiding reductions in accuracy for any given task.
US11559216B1 Integrated photodiode
This relates to one or more integrated photodiodes on a back surface of a PPG device. The one or more integrated photodiodes can reduce the gap between one or more windows and the active area of the photodiode(s) to increase the PPG signal strength without affecting the depth of light penetration into skin tissue. In some examples, the photodiode stackup can contact the surface of the windows. In some examples, the photodiode stackups can exclude a separate substrate. In some examples, the photodiode stackup can be deposited on the inner surface of the windows opposite the outer surface of the device. In some examples, the photodiode stackup can be deposited on the back surface and/or outer surface of the device. In this manner, PPG sensors can be included in the device without the need for extra layers and measurement accuracy can be improved due to lower light loss.
US11559214B2 Diagnostic and therapeutic device for compromised vascular hemodynamics analysis
An integrated triad system to measure a patient's blood pressure at different body positions, to instruct the patient when to move from one position to the next to alleviate vascular hypertension based on an algorithm stored in the system calculating blood pressure changes and predictive risk, and to transmit the result to a remote medical location. Using the integrated triad system to perform the test over a period can increase test sensitivity by accommodating the variable onset of the disease.
US11559212B2 Cardiac tissue penetrating devices, methods, and systems for treatment of congestive heart failure and other conditions
According to one embodiment, a tissue penetrating device includes an elongate shaft having a proximal end, a distal end, and a lumen extending there between. A first needle is disposed within the lumen of the elongate shaft and is extendable therefrom between a first configuration and a second configuration. In the first configuration, the first needle is disposed within the elongate shaft's lumen and is substantially aligned with an axis of the lumen. In the second configuration, the first needle extends distally of the elongate shaft's distal end and bends away from the lumen's axis. A second needle is disposed within a lumen of the first needle and is extendable therefrom when the first needle is positioned in the first configuration and when the first needle is positioned in the second configuration. The second needle may be extended from the first needle to penetrate tissue of a patient.
US11559200B2 Method and apparatus for measuring a property of an eye
Embodiments of the present invention provide a computer-implemented method of determining a parameter indicative of dark adaptation of an eye, comprising receiving threshold data from a dark adaptometer indicative of a perception threshold of the eye, fitting first and second models to the threshold data, wherein the first model is associated with a first dark adaptation mechanism and the second model is associated with the first dark adaption mechanism and a second dark adaptation mechanism, determining a confidence associated with the fitting of each of the first and second models to the received threshold data, iteratively repeating the steps of receiving the threshold data and fitting the first and second models in dependence on the determined confidence, and outputting an indication of one or more parameters indicative of dark adaptation of an eye associated with one or both of the first and second models.
US11559199B2 Visual contrast sensitivity cards for pediatric subjects
A visual stimulus for a set of contrast cards is provided which comprises a hollow outer circle, opposing and identical first and second arc segment within the outer circle which are symmetrical about the vertical diameter of the outer circle, a first filled-in circle and a second filled-in circle being identical in diameter to the first filled-in circle, each residing on opposite ends of the horizontal diameter of the outer circle and each being equidistant from the center of the outer circle, a filled-in center element having a rotational center on the center of the outer circle, the center element being symmetrical about both the horizontal and vertical diameter of the outer circle.
US11559192B2 Systems and methods for visualizing ablated tissue
Systems and methods for visualizing ablated tissue are disclosed. In some embodiments, a system for imaging tissue comprising: a catheter having a distal end and a proximal end; an inflatable balloon disposed about the distal end of the catheter; and an optical housing extending from the distal end of the catheter into the balloon, the optical housing being configured to position inside the balloon a light source for illuminating a tissue outside the balloon and a camera for imaging the illuminated tissue.
US11559187B2 Multistage pushbutton switch device and multistage pushbutton switch device for endoscope
In a multistage pushbutton switch device, n pushbutton switches and at least one load absorption spring are movably arranged in between a pushbutton member and a reaction force wall in the same axial line, each of the n pushbutton switches is composed of an electrical switch member and a pressing member that operates the electrical switch member, and (n−1) that is one less than n, or more pushbutton switches is arranged with an intermediate spring member, when the pushbutton member is pressed and displaced, the n electrical switch members are sequentially turned on, the load absorption spring is arranged in at least one of between the pushbutton member and the pushbutton switch that is the nearest to the pushbutton member, between pushbutton switches that are adjacent, and between the reaction force wall and the pushbutton switch that is the nearest to the reaction force wall.
US11559184B2 Integrated chemical delivery and cleaning systems
An integrated chemical delivery and cleaning system is provided. The system includes a cleaning medium. The system also includes a plurality of chemicals infused into portions of the cleaning medium. The system further includes a plurality of membranes configurable within the cleaning medium and designed to compartmentalize a plurality of regions within the cleaning medium. Additionally, the system includes a surface layer positionable on a surface of the cleaning medium wherein the surface layer is structured to include materials designed to clean surfaces of objects.
US11559182B2 Autonomous floor cleaner with drive wheel assembly
An autonomous floor cleaner can include a housing, a drive system for autonomously moving the housing over the surface to be cleaned, and a controller for controlling the operation of the autonomous floor cleaner. The drive system can include at least one drive wheel for driving the housing across a surface to be cleaned. The drive wheel can be selectively moved from an engaged or in-use position to a disengaged or maintenance position. In the disengaged or maintenance position, the wheel is disengaged from the autonomously moveable housing such that it can be pivoted, extended, removed, or otherwise moved farther away from the autonomously moveable housing.
US11559180B2 Filter system and a vacuum cleaner incorporating a filter system
A filter system for a vacuum cleaner is disclosed. The system comprises a housing reconfigurable relative to a bin between an operative configuration in which the housing is disposed upon the bin so that dirt separated from dirt-laden air can collect in the bin, and an idle configuration in which the housing is removed from the bin. The housing comprises an inlet for receiving dirt-laden air into the housing, an outlet via which cleaned air can exit the housing. The system further comprises first filtering means and second filtering means disposed within the housing, the first filtering means being positioned upstream of the second filtering means. The first and second filtering means comprises a filter medium configured to separate dirt from the dirt-laden air passing from the inlet to the outlet through the filter medium. The system further comprises filter cleaning means for removing dirt from the filter medium of the first filtering means when the housing is configured at least in the operative configuration.
US11559179B2 Self-propelled pathogen detection device, pathogen detection system, and control method
The present disclosure provides a self-propelled pathogen detection device in which a place where a pathogen is highly likely to be present in a space such as an inside of a facility is allowed to be configured preferentially to be a target region of detection. The self-propelled pathogen detection device according to the present disclosure comprises a housing; a detection part for detecting a pathogen; a movement mechanism for moving the housing; a position acquirement part for acquiring position information representing a current position of the housing in a space; and a control part which determines a target region in the space on the basis of traffic line information on a person in the space, and controls the movement mechanism to move the housing in the target region on the basis of the position information. The detection part detects the pathogen in the target region.
US11559171B2 Bath with elliptical air flow and/or moveable bottom
A pet bath may include a tub, a cover connected to an upper rim of the tub, a jet provided in the tub to discharge bubbles, an air outlet provided in the tub to discharge air, and a sterilizer to sterilize the tub. The tub may have a bottom plate that is raised and lowered relative to a bottom frame having a drain and a filter assembly so that liquid in the tub flows between edges of the bottom plate and an inner surface of the tub toward the bottom frame to be drained and filtered.
US11559168B2 Bread toaster accessory for melting cold solid spreads
An accessory for efficiently melting or softening cold solid spreads using the heat emanating from a bread toaster that in turn is easy to use or clean; reduces the risk of spillage; and can be used on any conventional toaster.
US11559165B2 Apparatus for preparing a coffee beverage
A coffee brewer contains a brewing unit in which coffee grounds having been poured in are compressed by a plunger driven by an actuator. Heated water flows through the compressed coffee grounds. A control device controls the actuator in accordance with signals of an angle of rotation sensor. The control device first moves the plunger against a stop in an ejection position to calibrate the sensor, then moves the plunger by a predetermined distance in a downwards direction into a pouring-in position. Afterwards the control device moves the plunger by a second distance into the brewing position, a length of the predetermined distance and the second distance corresponds to a number of pulses of the sensor which are stored in the memory. The control device subsequently moves the plunger by a third distance back into the ejection position in which the coffee grounds are removed from the plunger.
US11559164B2 Coaxial microwave rotary applicator for material processing
Disclosures of the present invention describe a coaxial microwave rotary applicator for material processing, mainly comprising: a waveguide unit, a microwave generator connected to one end of the waveguide unit, a bearing unit, a chamber, a rotary shaft, a driver unit, a sampling unit. The bearing unit is connected to the waveguide unit through a non-rotary ring, and the chamber is connected to a rotary ring of the bearing unit, and the microwave generator is configured for supplying a microwave to the chamber. By such arrangements, it is able to uniformly heat a specific material disposed in the chamber by driving the chamber to rotate. It is worth noting that, a user is allowed to clearly observe the processing progress via the sampling unit during the heating process of the specific material.
US11559161B1 Temperature regulated preparation and storage system
A temperature-regulated apparatus for food and drink preparation and storage, particularly for refrigeration and sous vide cooking. The apparatus is preferably a consumer electronic device comprising a compartment, base, reservoir, tube network, heating and cooling element, and an air pump system. The apparatus is controlled electronically and wirelessly in connection with a hardware and software system.
US11559160B2 Automated immersion apparatus and method for cooking meals
A system and method for storing, preserving and cooking meals using the sous-vide technique. The system and method of the present invention is designed to automatically cook, upon request a meal having various ingredients by immersing bagged food in temperature-controlled liquid. The cooking time may be manually or automatically programmed from downloaded cooking direction associated with the food. The cooking request may be given by a user from the physical apparatus or using a mobile device application.