Document Document Title
US11401541B2 Solid form of (-)-Ambrox formed by a bioconversion of homofarnesol in the presence of a biocatalyst
A solid form of (−)-Ambrox formed by a bioconversion process.
US11401537B2 Process for producing polyhydroxyalkanoate
High levels of polyhydroxyalkanoates (PHA) can be produced from wastewater comprising Readily Biodegradable COD (RBCOD) using activated sludge comprising microorganisms capable of accumulating PHA by contacting the wastewater with the activated sludge in the presence of dissolved oxygen during a first period of time, to obtain PHA-loaded activated sludge, and then supplying elements essential for growth such as nitrogen and phosphorus and allowing up-take of these elements and limited growth during a second period of time, the supplied amount of at least of one of said essential elements compared to the amount of RBCOD supplied in step a) limiting the growth to an extent that not all PHA is used for growth, to obtain grown activated sludge; and removing or harvesting part of the PHA-loaded activated sludge and/or part of the grown activated sludge, so that the total average retention time of the sludge is less than 72 h.
US11401534B2 Microorganisms for the production of 1,4- butanediol and related methods
The invention provides non-naturally occurring microbial organisms comprising a 1,4-butanediol (BDO) pathway comprising at least one exogenous nucleic acid encoding a BDO pathway enzyme expressed in a sufficient amount to produce BDO and further optimized for expression of BDO. The invention additionally provides methods of using such microbial organisms to produce BDO.
US11401528B2 Replication-defective arenavirus vectors
The invention relates to an infectious arenavirus particle that is engineered to contain a genome with the ability to amplify and express its genetic information in infected cells but unable to produce further infectious progeny particles in normal, not genetically engineered cells. One or more of the four arenavirus open reading frames glycoprotein (GP), nucleoprotein (NP), matrix protein Z and RNA-dependent RNA polymerase L are removed or mutated to prevent replication in normal cells but still allowing gene expression in arenavirus vector-infected cells, and foreign genes coding for an antigen or other protein of interest or nucleic acids modulating host gene expression are expressed under control of the arenavirus promoters, internal ribosome entry sites or under control of regulatory elements that can be read by the viral RNA-dependent RNA polymerase, cellular RNA polymerase I, RNA polymerase II or RNA polymerase III. The modified arenaviruses are useful as vaccines and therapeutic agents for a variety of diseases.
US11401522B2 Fungal genome modification systems and methods of use
Compositions and methods are provided for genome modification at a target site in the genome of a fungal cell. The methods and compositions are drawn to a guide polynucleotide/Cas endonuclease system for promoting modification of the DNA sequence at a target site in a fungal host cell genome.
US11401518B2 Methods of reducing expression of x-inactivation escapee genes and autosomal genes
Inhibitory nucleic acids, e.g., antisense oligonucleotides (ASO) against PAR-TERRA RNA or other chromosome-specific TERRA transcripts (i.e., inclusive of chromosome-specific subtelomeric sequences), and methods of use thereof to downregulate expression of escapee genes on the inactive X chromosome, expression from the active X chromosome, subtelomeric autosomal loci (e.g., FSHD locus), or expression of autosomal genes involved in growth control and apoptosis, e.g., in cells and subjects with supernumerary X chromosomes and/or cancer and other human diseases.
US11401509B2 Methods of minimizing glycoprotein agregation in CHO cell production
In accordance with the present invention, CHO cells expressing a recombinant polypeptide of interest are grown in media where the amino acids, vitamins, phosphate, lipids and/or antioxidant optimization is utilized to manipulate and/or control the protein quality attributes of the polypeptides. Polypeptides expressed in accordance with the present invention may be advantageously used in the preparation of pharmaceutical compositions.
US11401504B2 Method for inducing antigen specific CD8 positive T cells
Provided is a method for inducing CD4−CD8+ T cells having an antigen specific cytotoxic activity from pluripotent stem cells, comprising the steps of: (1) differentiating pluripotent stem cells to give a cell culture comprising CD4−CD8− T cells and CD4+CD8+ T cells, (2) removing CD4−CD8− cells from the cell culture obtained in step (1), and (3) differentiating the CD4+CD8+ cells in the cell culture into CD4−CD8+ T cells.
US11401501B2 Methods for culturing organoids
The present invention provides a method for culturing organoids, the method comprising: a) disassociating unprocessed organoids to produce a cell suspension; b) sieving the cell suspension through a cell strainer to retain a sieved cell suspension containing cells of about 10 μm to about 1 mm in diameter; and c) seeding cells of the sieved cell suspension into a bioreactor in a cell culture medium comprising an extracellular support matrix.
US11401500B2 System, method, and composition for incubating spores for use in aquaculture, agriculture, wastewater, and environmental remediation applications
A system and method for generating an incubated bacteria solution by heating a nutrient germinant composition and bacteria, including at least one species in spore form, to a preferred temperature a range of 35-50° C. for 2-60 minutes using exothermic chemical reaction heat. An incubated bacteria solution is preferably generated at or near a point-of-use in an aquaculture, agriculture, wastewater, or environmental remediation application. The nutrient-germinant composition comprises L-amino acids, optionally D-glucose and/or D-fructose, a buffer, an industrial preservative, and may include bacteria spores (preferably of one or more Bacillus species) or they may be separately combined for incubation. A first chemical contained in a pouch is activated by contact with a second chemical, water, or air in a flameless heater to initiate exothermic reaction to provide incubation heat. A potable, single-use incubation bag is configured to hold the flameless heater and a container of nutrient germinant composition and spores.
US11401494B2 Cell processing system and method with fill options
A variety of fill options is provided for a cell processing system. Certain options relate to a syringe assembly that receives a product directly from a separator. Other options relate to a filling system associated with the cell processing system, the filling system comprising one or more filling stations, each with at least one container, that receive product from a product container associated with the cell processing system.
US11401493B2 Packed-bed bioreactor systems and methods of using the same
A packed-bed bioreactor system for culturing cells is provided, the system including a cell culture vessel having at least one interior reservoir, an inlet fluidly connected to the reservoir, and an outlet fluidly connected to the reservoir; and a cell culture matrix disposed in the reservoir. The cell culture matrix includes a structurally defined multi-layered substrate for adhering cells thereto, and each layer of the multi-layered substrate has a physical structure and a porosity that are substantially regular and uniform.
US11401489B2 Water-soluble multicompartment unit dose article
A water-soluble multicompartment unit dose article having a weight ratio of laundry detergent to total water-soluble film in the water-soluble multicompartment unit dose article of at least 45:1.
US11401487B2 Cleaning formulation for removing residues on surfaces
This disclosure relates to a cleaning composition that contains 1) at least one redox agent; 2) at least one first chelating agent, the first chelating agent being a polyaminopolycarboxylic acid; 3) at least one metal corrosion inhibitor, the metal corrosion inhibitor being a substituted or unsubstituted benzotriazole; 4) at least one pH adjusting agent, the pH adjusting agent being a base free of a metal ion; and 5) water. This disclosure also relates to a method of using the above composition for cleaning a semiconductor substrate.
US11401485B2 Microcapsule system for polysensory olfactory effects I
A microcapsule system having an outer microcapsule with an outer capsule shell is disclosed. The outer microcapsule comprises at least one inner microcapsule with an inner capsule shell and a first fragrance composition. The inner microcapsule comprises a second fragrance composition that differs from the first fragrance composition. Methods for the production of such micr, products that contain said microcapsules, methods for producing polysensory olfactory impressions and to the corresponding use of the microcapsule system.
US11401477B2 Fuel blend comprising a mixture of aryl ethers
The present invention relates to middle distillate fuel blends, in particular renewable diesel fuel blends comprising a mixture of aryl ethers.
US11401475B2 Production of light olefins from crude oil via fluid catalytic cracking process and apparatus
A reactor system configured for efficiently removing contaminants (CCR, nickel, vanadium, nitrogen, sodium, iron, calcium, chlorine etc.) from a heavy portion of the crude oil. The products are routed to a common main fractionation section. The heavy feed with lower contaminants may then be processed in a fluid catalytic cracking (FCC) unit, the overall concept employing a fluid catalytic reaction platform with carbon rejection approach. Also disclosed is a reactor system for efficiently processing crude oil in a fluid catalytic cracking unit with a dual-reactor and dual catalyst system to maximize petrochemical building blocks such as ethylene, propylene, butylenes, BTX (benzene, toluene and xylene) rich naphtha from a variety of crude oils.
US11401472B2 Washing and desalting device, washing and desalting method, desalting and dehydrating system, and desalting and dehydrating method
A washing and desalting device includes a first shell and a plurality of filaments. The first shell has a first receiving cavity and is provided with a liquid inlet and a liquid outlet that communicate with the first receiving cavity. The plurality of the filaments is provided in the first receiving cavity, and the length direction of each of the filaments is consistent with that of the first receiving cavity. The device can be incorporated in a washing and dehydrating system.
US11401471B2 Simulated distillation using gas chromatography with vacuum ultraviolet detection
A method to simulate distillation of a petroleum stream by gas chromatography can include separating the petroleum stream with a gas chromatograph as a function of boiling point; passing the separated petroleum stream through a vacuum ultraviolet detector to yield data comprising a vacuum ultraviolet signal as a function of boiling point; integrating the vacuum ultraviolet signal as a function of boiling point over two or more wavelength ranges to derive relative concentrations of two or more components of the separated petroleum stream that correspond to the two or more wavelength ranges.
US11401463B2 Luminescent particles based on rare earth elements and use thereof as a diagnostic agent
The present invention concerns a luminescent particle comprising a nanoparticle of formula A1-xLnxVO4(1-y)(PO4)y  (I) in which A is selected from yttrium (Y), gadolinium (Gd), lanthanum (La), and mixtures thereof; Ln is selected from europium (Eu), dysprosium (Dy), samarium (Sm), neodymium (Nd), erbium (Er), ytterbium (Yb), and mixtures thereof; 0100 μS·cm−1. It also concerns a method for preparing such luminescent particles, a colloidal suspension of these particles, and the use thereof as a diagnostic agent, and also a diagnostic kit comprising such luminescent particles.
US11401460B2 Methods for pressure protection using a gas
Disclosed are compositions and methods for the pressure protection of existing wells during infill drilling operations. The methods can include injecting a gas into the existing wellbore in fluid communication with an unconventional subterranean formation prior to and/or during fracturing of the new wellbore in fluid communication with the unconventional subterranean formation.
US11401455B2 Low pH crosslinking of polymers
The invention is directed to polymers that self-crosslink at acidic pH or can be crosslinked by phenolic agents in brine. Such polymers have lower viscosity and can be pumped deep into reservoirs, where they will cross link in situ, thus increasing their viscosity and/or form a gel and blocking thief zones. Methods of making and using such polymers are also provided.
US11401451B2 Fiber reinforced flexible foams
A flexible foam composition comprising a flexible foam structure comprising a plurality of struts, and a plurality of fibers, where a majority of the fibers are associated with the struts. The fibers may be thermally conductive fibers. The fibers include, but are not necessarily limited to, homopolymer and/or copolymer fibers having a glass transition temperature (Tg) of −50° C. (−58° F.) or greater, carbon fibers, animal-based fibers, plant-based fibers, metal fibers, and combinations thereof. The presence of fibers can impart to the flexible foam composition greater indentation force deflection (IFD), greater static thermal conductivity, improved compression set, improved height retention or durability, and/or a combination of these improvements. The flexible foam composition may be polyurethane foam, latex foam, polyether polyurethane foam, viscoelastic foam, high resilient foam, polyester polyurethane foam, foamed polyethylene, foamed polypropylene, expanded polystyrene, foamed silicone, melamine foam, among others.
US11401449B2 Methods of forming an adhesive composition from asphalt shingle waste powder
Non-limiting embodiments of the present disclosure relate to a method comprising: obtaining asphalt shingle waste (ASW) and performing grinding, screening, and separating steps on the ASW. In some embodiments, granules are removed from the ASW. In some embodiments, the method transforms ASW into ASW powder. In some embodiments, the ASW powder is formed into a plurality of briquettes. In some embodiments, at least one of: the ASW powder, the plurality of briquettes, or any combination thereof is fed into a mixing process that results in an ASW powder filled coating. In some embodiments, the ASW powder is formed into an adhesive composition.
US11401446B2 Electroconductive adhesive composition
An object of the present invention is to provide an electroconductive adhesive composition which has excellent thermal conductivity and which, even when repeatedly undergoing fluctuations in temperature, is less apt to cause adherend separation. The present invention relates to an electroconductive adhesive composition which contains: an electroconductive filler (A) containing metal particles (a1) having an average particle diameter of 0.5-10 μm and silver particles (a2) having an average particle diameter of 10-200 nm; and particles (B) of a thermoplastic resin which is solid at 25° C.
US11401443B2 Adhesion-regulating agents and methods for tuning adhesion strength of acrylic adhesives by substrate modification
Adhesion-regulating agents for enhancing the adhesion values of acrylic adhesives, and methods of using adhesion-regulating agents for treating a removable flooring substrate surface for tuning the adhesion of the flooring substrate surface to objects comprising an acrylic adhesive are disclosed.
US11401442B2 Polishing liquid and chemical mechanical polishing method
A polishing liquid is used for chemical mechanical polishing and includes colloidal silica; and an onium salt containing a cation, in which a content of the onium salt is more than 0.01% by mass, a zeta potential of the colloidal silica measured in a state where the colloidal silica is present in the polishing liquid is 15 mV or more, an electrical conductivity is 10 μS/cm or more, and a pH is 2 to 4.
US11401435B2 Aqueous primer and aqueous white inkjet ink composition set for lamination
An object is to improve the lamination strength and anti-blocking suitability of matters printed with an aqueous white inkjet ink composition containing titanium oxide, etc., on polyethylene terephthalate, polypropylene, nylon, and other resin films. As a means for achieving the object, an ink set is provided that includes a combination of: an aqueous primer composition containing an acrylic resin and/or vinyl acetate resin, and a calcium salt; and an aqueous white inkjet ink composition containing a polyester polyurethane resin emulsion with a rate of elongation of 500 to 1500% by 0.1 to 10.0 percent by mass in solids content in the aqueous white inkjet ink composition, a wax emulsion, and a titanium oxide.
US11401432B2 Curable composition, accommodating unit, device for forming two or three dimensional image, method of forming two or three dimensional image, and cured matter
A curable composition contains a polymerizable compound and a polymerization initiator containing pheylbis(2,4,6-trimethyl benzoyl)phosphine oxide and diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide in a mass ratio of pheylbis(2,4,6-trimethyl benzoyl)phosphine oxide:diphenyl(2,4,6-trimethylbenzoyl)phosphine oxide from 1:6 to 1:160, wherein supernatant obtained after the curable composition is centrifuged for 30 minutes at 70,000 rotation per minute has an absorbance of 0.02 or less at a wavelength of 700 nm.
US11401431B2 Thermal inkjet ink and colorless pre-treatment fluid
A thermal inkjet ink includes a water-based vehicle; a colorant; and a modified siloxane surfactant including a plurality of components. Each component has a chemical formula I: Si(1+x+z)O(1+x+z+y)C(1+1+2(x+z)+j+m+y(2+n))H(6+6+6(x+z)+o+p+y(4+q)). For each component: y ranges from 2 to 4; x and z each range from 0 to 14; x+z=from 0 to 14; j, m, and n are the number of carbon atoms, respectively, in R1, R2, and R3; o, p, and q are the number of hydrogen atoms, respectively, in R1, R2, and R3. R1 is selected from H, an alkyl, and an aryl. Each of R2 and R3 is selected from H, an alkyl, an alkyl substituted with an allylic or an epoxy group, an aryl, and an aryl substituted with an allylic or an epoxy group. For some components: x+z=from 7 to 14.
US11401429B2 Aqueous ink compositions
The present disclosure is drawn to aqueous ink compositions, methods of printing on offset coated print media, and printing systems. In one example, the aqueous ink compositions can include from 2 wt % to 5 wt % pigment, from 70 wt % to 95 wt % water, from 1 wt % to 10 wt % binder, from 0.1 wt % to 3 wt % non-ionic surfactant, from 1 wt % to 15 wt % humectant solvent including a hydrophilic group, and from 0.3 wt % to 4.5 wt % non-volatile glycol ether co-solvent having a boiling point of 220 C or greater.
US11401428B2 Coating agent compositions that are suitable for dip coating and that cure at low temperature
Aqueous coating compositions are provided. The aqueous compositions include at least one type of organic polymer particles having an average particle size of 10 to 1000 nm, including isocyanate-reactive polymers (A), one or more ketoxime- and/or pyrazole-blocked polyisocyanates (B) including at least one aromatic hydrocarbyl radical or at least one cycloaliphatic hydrocarbyl radical, at least one polyanionic polymer (C), at least one complex fluoride (D) selected from the group consisting of hexa- or tetrafluorides of metallic elements of groups IVb, Vb and VIb of the Periodic Table of the Elements, and at least one aminosilane (E), wherein the aqueous coating compositions have a pH of 3 to 5, and have a total solids content of 5% to 35% by weight. Also provided are processes for producing these aqueous coating compositions, processes for coating metal ion-releasing surfaces with the aqueous coating compositions, and coatings obtained therefrom.
US11401424B2 Age-resistant asphalt compositions and methods
Aging resistant asphalt compositions and related methods of preparing and applying the same are provided. The aging resistant asphalt compositions can include a base asphalt with specified properties combined with an aging resistance additive, to produce modified asphalt compositions having a colloidal index within the range of about 3.7 to about 8.0, a saturates content of less than about 10% by weight, and measurable age-resistant properties. The aging resistant asphalt compositions are useable in a variety of asphalt paving and non-paving applications. The aging resistant asphalt compositions provide improved resistance to both moderate and low failure temperatures of conventional paving asphalts throughout its service life by reducing age-related failures.
US11401423B2 Surface treated-metal oxide particle material, method for producing same, resin composition for electronic material, and filler for silicone resin material
Provided is a filler that has a low viscosity when mixed in a resin material and has reduced permittivity and dielectric loss tangent. The filler includes: a metal oxide particle material; and a polyorganosiloxane compound with which a surface treatment is performed on the metal oxide particle material and which is represented by general formula (1): (RO)3Si—(SiR2—O—)n—SiR3 (in general formula (1), each R is independently selected from among alkyl groups having 1 to 4 carbon atoms, and n is not less than 10 and not greater than 200). A resin composition obtained by containing the filler in a resin is suitable for an electronic material.
US11401422B2 Liquid silicone rubber composition
A liquid silicone rubber (LSR) composition, and articles and coatings made therewith are disclosed. Also disclosed is a process to provide for the composition, and a process to coat on textile.
US11401421B2 Addition-curable silicone rubber composition
The purpose of the present invention is to provide an addition-curable silicone rubber composition which gives a cured product having a controlled oil-bleeding property and releasability from a mold, without increasing an amount of a bleeding oil to be added.Thus, the present invention provides an addition-curable silicone rubber composition comprising the following components (A) to (D): (A) 100 parts by mass of an organopolysiloxane having at least two alkenyl groups each bonded to a silicon atom, (B) 0.2 to 20 parts by mass of an organohydrogenpolysiloxane having at least two hydrogen atoms each bonded to a silicon atom, (C) a catalytic amount of a platinum group metal catalyst, and (D) 1 to 10 parts by mass of a silicone oil represented by the following formula (1): wherein R1 is, independently of each other, an unsubstituted monovalent hydrocarbon group having 1 to 10 carbon atoms, R2 is, independently of each other, a monovalent aromatic hydrocarbon group having 6 to 12 carbon atoms, the amount of the monovalent aromatic hydrocarbon group is at least 35 mol % and less than 50 mol %, relative to a total amount of all substituents each bonded to a silicon atom, that is, all of R1 and R2, m is an integer of from 0 to 3, m′ is an integer of from 0 to 3, n′ is an integer of from 0 to 3, n is an integer of from 10 to 20, and m+m′+n+n′ is in a range of from 10 to 22.
US11401416B2 Flame retardant polyamide composition
A polyamide composition comprising a polyamide; a plurality of inorganic fibers; and a flame retardant system comprising a zinc phosphinate and a nitrogen-containing polyphosphate is provided. At thicknesses of from about 0.4 to about 3.2 millimeters, the composition exhibits a Glow Wire Ignition Temperature of about 775° C. or more as determined in accordance with IEC-60695-2-13:2010; a Glow Wire End Product Temperature (without flame) of about 750° C. or more as determined in accordance with IEC-60335-1:2010; a Glow Wire Flammability Index of about 850° C. or more as determined in accordance with IEC-60695-2-12:2010; a V0 rating as determined in accordance with UL94; and/or a comparative tracking index of about 550 volts or more as determined in accordance with IEC 60112:2003.
US11401414B2 Flame-retardant poly(butylene terephthalate) resin composition
The present invention addresses the problem of suppressing corrosion of a molding machine or mold when molding a polybutylene terephthalate resin composition that uses a halogenated benzyl acrylate-based flame retardant as a flame retardant and suppressing corrosion of a metal terminal in an insert-molded article that uses the polybutylene terephthalate resin composition. The problem is solved by a polybutylene terephthalate resin composition that uses a halogenated benzyl acrylate-based flame retardant as a flame retardant, wherein the amount of halogenated aromatic compounds such as chlorobenzene in the manufacturing process for the flame retardant is suppressed.
US11401413B2 Injection-molded article containing surface-modified silicates
The present invention relates to an injection molded article comprising: i) 27% to 87% by weight based on the total weight of the components i to iv of a polyester constructed from aliphatic dicarboxylic acids and aliphatic diols; ii) 3% to 15% by weight based on the total weight of the components i to iv of an aliphatic-aromatic polyester comprising: ii-a) 30 to 70 mol % based on the components ii-a to ii-b of a C6-C18-dicarboxylic acid; ii-b) 30 to 70 mol % based on the components ii-a to ii-b of terephthalic acid; ii-c) 99 to 100 mol % based on the components ii-a to ii-b of 1,3-propanediol or 1,4-butanediol; ii-d) 0% to 1% by weight based on the components ii-a to ii-c of a chain extender and/or branching agent; iii) 0% to 35% by weight based on the total weight of the components i to iv of polylactic acid; iv) 10% to 35% by weight based on the total weight of the components i to iv of at least one surface-modified silicate selected from the group consisting of: kaolin, muscovite, montmorillonite, talc and wollastonite.
US11401412B2 Polyester for profile extrusion and/or pipe extrusion
Thermoplastic molding compositions containing A) from 29 to 99.99% by weight of a polyester, B) from 0.01 to 10% by weight of an ionomer composed of at least one copolymer of B1) from 30 to 99.9% by weight of ethylene B2) from 0 to 60% by weight of 1-octene or 1-butene or propylene or a mixture of these and B3) from 0.01 to 70% by weight of functional monomers, where the functional monomers are selected from the group of the carboxylic acid groups, carboxylic anhydride groups, carboxylic ester groups and mixtures of these, where component B) has been neutralized to an extent of at least 20% with alkali metal ions, based on 100% by weight of A) and B), and C) from 0 to 70% by weight of other additional substances, where the sum of the % by weight values for A) to C) is 100%, for use in the production of cable sheathing or optical-conductor sheathing via blow molding, profile extrusion, and/or pipe extrusion.
US11401411B2 Isoporous self-assembled block copolymer films containing high molecular weight hydrophilic additives and methods of making the same
The invention provides systems and methods for substantially improving the compaction resistance of isoporous block copolymer (BCP) film by adding a high molecular weight hydrophilic additive in the casting dope formulation. Systems and methods disclosed also disclose several other multifunctional enhancements to film properties including: low fouling propensity, improved permeability, improved permeability retention upon drying, and ability to tune the substructure and pore size of these novel BCP films. These porous BCP films are useful in filtration and separations applications and are amenable to standard manufacturing practices.
US11401408B2 Polymer particles
A polymer particle includes a first heteropolymer composition and a second heteropolymer composition having a higher glass transition temperature (Tg) than a Tg of the first heteropolymer composition. The first heteropolymer composition includes two or more aliphatic (meth)acrylate ester monomers or two or more aliphatic (meth)acrylamide monomers. The second heteropolymer composition includes a cycloaliphatic monomer and an aromatic monomer. The cycloaliphatic monomer is selected from the group consisting of a cycloaliphatic (meth)acrylate monomer and a cycloaliphatic (meth)acrylamide monomer and the aromatic monomer is selected from the group consisting of an aromatic (meth)acrylate monomer and an aromatic (meth)acrylamide monomer.
US11401406B2 Polyethylene resin composition
The present disclosure relates to a polyethylene resin composition exhibiting excellent processability and bubble stability, which can provide a film or fiber having excellent physical properties through various processes. The polyethylene resin composition includes a first polyethylene resin having a density of 0.950 g/cm3 to 0.960 g/cm3, a weight average molecular weight of 80000 g/mol to 100000 g/mol and a molecular weight distribution of 3.3 to 4.0; and a second polyethylene resin having a density of 0.950 g/cm3 to 0.960 g/cm3, a weight average molecular weight of 500000 g/mol to 600000 g/mol and a molecular weight distribution of 1.3 to 2.0.
US11401404B2 Method for preparing polyolefin-acrylic particles
Provided is a process for making a dispersion of composite particles comprising (i) providing a dispersion of crosslinked polyolefin particles in an aqueous medium, (ii) performing emulsion polymerization on one or more vinyl monomers in the presence of the crosslinked polyolefin particles to produce the dispersion of composite particles.
US11401403B2 Article containing both thermoplastic and elastomer
A latex formulation comprising elastomer, thermoplastic, accelerator, antifoaming agent, antioxidant, crosslinker, colouring agent, surfactant, filler, pH adjuster and dispersing medium, wherein the latex formulation has a total solid content ranging between 5% by weight to 40% by weight. A method of preparing a latex formulation to manufacture a glove containing both thermoplastic and elastomer, wherein the method comprises the steps of blending elastomer with thermoplastic to produce a dispersion and stirring the dispersion, adding while stirring accelerator, antifoaming agent, antioxidant, crosslinker, colouring agent, surfactant and filler one after another with no particular order and followed by pH adjuster into the dispersion to produce latex formulation and stirring continuously and allowing to mature, wherein total solid content is adjusted to between 5% by weight to 40% by weight by way of addition of dispersing medium and wherein pH range of the latex formulation is adjusted to between 9 to 11.
US11401402B2 Compositions and methods for removal of pressure sensitive adhesives
A composition for removal of adhesives comprises a polar solvent, such as benzyl alcohol, in combination with thickeners, dry lubricants, and/or gelling agents to allow for penetration of the adhesive and transformation of the treated adhesive into a solid material that can be readily removed from a surface without forming sticky residue that adheres to the solid material or tool used to remove the adhesive.
US11401396B2 Methods of manufacturing articles utilizing foam particles
Methods for manufacturing articles, including articles of footwear, apparel, and sporting equipment are provided. The methods comprise decorating a plurality of foam particles. The decorating can comprise applying a coating on the foam particles, or embossing or debossing the foam particles, or both. The decorating can comprise applying a coating on the foam particles by printing, painting, dyeing, applying a film, or any combination thereof. The plurality of foam particles are affixed utilizing aspects of additive manufacturing methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.
US11401392B2 Barrier film composition
Barrier films are prepared from a composition comprising 1) a blend of two high density polyethylene HDPE blend components, 2) zinc glycerolate and 3) a dispersion aid/synergist. The two high density polyethylene blend components have substantially different melt indices. It is difficult to properly mix the zinc glycerolate into this HDPE blend. The use of the dispersion aid/synergist improves the water vapor transmission rate (WVTR) of polyethylene film (in comparison to barrier films made with zinc glycerolate, in the absence of the dispersion aid/synergist). The resulting barrier films are suitable for the preparation of packaging for dry foods such as crackers and breakfast cereals.
US11401391B2 Oyster paper and manufacturing method thereof
An oyster paper and a manufacturing method thereof are provided. The oyster paper is made of 60%-70% oyster shell powder, 10%-20% polymer, 15%-17% natural biodegradation inducing agent, and 3%-5% natural biodegradation assisting additive agent, by volume ratio, which are subjected to mixing and pre-melting processing, followed by compounding and pelletizing to prepare oyster paper pellets, which are then subjected to film blowing processing to be film-blown into an oyster paper product having a thickness of 0.05-0.5 millimeters. The oyster paper possesses the quality of wood pulp paper and shows bettered stiffness and wider applications. The oyster paper also provides, after being disposed and buried, an effect of being 100% natural degradation into compost for fertilizing the soil. As such, a kind of oyster paper featuring recycling and reuse of oceanic creature waste shell and natural microorganism induced degradation for composting and recycling and a manufacturing method thereof are provided.
US11401387B2 Photocontrolled dynamic covalent linkers for polymer networks
Reversibly crosslinkable polymeric networks, including reversibly crosslinkable hydrogel networks are provided. Also provided are methods of making the polymeric networks and methods of using the hydrogel networks in tissue engineering applications. The reversibly crosslinkable polymeric networks are composed of polymer chains that are covalently crosslinked by azobenzene boronic ester bonds that can be reversibly formed and broken by exposing the polymeric networks to different wavelengths of light.
US11401386B2 Doubly-crosslinked, emulsion-templated hydrogels through reversible metal coordination
Doubly-crosslinked hydrogel polyHIPEs (DC-PHs), which exhibit rapid water absorption, enhanced mechanical properties, and shape memory behavior, are provided herein, as well as processes of producing the same and uses thereof. DC-PHs comprise a continuous HIPE-templated doubly-crosslinked hydrogel, formed from hydrogel-forming monomers, ligand-bearing monomers, and crosslinking monomers.
US11401384B2 Silicous film forming composition comprising block copolymer and method for producing siliceous film using same
According to the present invention, a siliceous film forming composition, which is capable of filling trenches having narrow widths and high aspect ratios and forming a thick film, can be provided. A siliceous film forming composition comprising: (a) a block copolymer comprising a linear and/or cyclic block A having a polysilane skeleton comprising 5 or more silicon and a block B having a polysilazane skeleton comprising 20 or more silicon, and (b) a solvent.
US11401382B2 Thermoplastic polyamide particles
Thermoplastic polyamide particles comprising at least one polyamide and at least one polymeric ionic compound comprising imidazolium groups (imidazolium compound), the thermoplastic polyamide particles having an ellipsoidal or approximately ellipsoidal shape with the largest diameter of 1 to 100 mm, preferably 2 to 10 mm, more preferably 3 to 8 mm.
US11401381B2 Modified silicone compound, and thermosetting resin composition, prepreg, laminate plate and printed wiring board using same
There are provided a modified silicone compound prepared by reacting: (A) a siloxane diamine represented by the general formula (1); (B) a maleimide compound with at least two N-substituted maleimide groups in the molecular structure; and (C) an amine compound with an acidic substituent; and also provided a thermosetting resin composition, a prepreg, a laminated plate, and a printed wiring board that are formed by using this compound. The multi-layered printed wiring board produced by using the laminated plate formed by using the prepreg obtained from the modified silicone compound and the thermosetting resin composition of the present invention through laminate molding has an excellent glass transition temperature, coefficient of thermal expansion, copper foil adhesion, hygroscopicity, hygroscopic solder heat resistance, and copper-stuck solder heat resistance. Therefore, the multi-layered printed wiring board is useful as a highly integrated semiconductor package and a printed wiring board for an electronic device.
US11401380B2 Poly(β-amino ester)-co-polyethylene glycol (PEG-PBAE-PEG) polymers for gene and drug delivery
Polyethylene glycol (PEG)-b-poly(β-amino ester) (PBAE) co-polymers (PEG-PBAE) and blends of PEG-PBAEs and PBAEs and their use for delivering drugs, genes, and other pharmaceutical or therapeutic agents safely and effectively to different sites in the body and to different cells, such as cancer cells, are disclosed.
US11401379B2 Oraganocarbonate-modified prepolymer, its use as a reactant for the preparation of isocyanate-free and isothiocyanate-free alkoxysilane polymers, and compositions thereof
The use of an organocarbonate-modified prepolymer having at least an average of 1.5 carbonate, thiocarbonate, carbamate or thiocarbamate groups bonded directly to the polymer backbone each via an oxygen atom, where each of these oxygen atoms has its origin in the reaction of a primary, secondary or tertiary hydroxyl group of the polymer backbone and a reactive compound selected from the group consisting of a diorganocarbonate, a diorganothiocarbonate, a cyclic carbonate, a cyclic thiocarbonate, an N,N-diheterocyclourea derivative and an N,N-diheterocyclothiourea derivative. Also, the preparation of the alkoxysilane polymers.
US11401371B2 Copolymerized saturated polyester resin and coating composition containing same
A copolymerized saturated polyester resin is formed by polycondensation of an acid component and an alcohol component. The acid component contains (a-1) 90 to 99% by mole of an aromatic dicarboxylic acid or a C1-2 alkyl ester thereof and (a-2) 0.5 to 2% by mole of a trifunctional or higher functional carboxylic acid or an anhydride thereof. The alcohol component contains (b-1) 45 to 80% by mole of an alicyclic polyhydric alcohol and (b-2) 20 to 55% by mole of an aliphatic polyhydric alcohol having a C1-3 alkyl side chain. A coating composition containing the copolymerized saturated polyester resin shows excellent corrosion resistance and chemical resistance. A coating film formed from the coating composition shows excellent processability and resin solubility, and is useful for coating a can and pre-coated metal.
US11401369B2 Rotaxane, crosslinked product of rotaxane, and methods for producing the same
An object of the present invention is to provide a novel rotaxane and a production method of the same. The present invention provides a rotaxane polyurea having a cyclic molecule and a polyurea chain piercing through the cyclic molecule.
US11401362B2 Water-soluble and/or water-swellable hybrid polymer
A water-soluble and/or water-swellable hybrid polymer comprising: (i) from 5 wt.-% to 95 wt.-% water-soluble and/or water-swellable polysaccharide polymer; (ii) from 5 wt.-% to 95 wt.-% synthetic polymer comprising: (a) from 40 mol-% to 99 mol-% of repeating units according to Formula (1) (b) from 0.01 mol-% to 5 mol-% crosslinking or branching units, wherein the crosslinking or branching units result from the incorporation of a monomer comprising at least two olefinically unsaturated double bonds; (c) from 0.99 mol-% to 59.99 mol-% of repeating neutral structural units; wherein components (i) and (ii) are polymerized by radical precipitation polymerization in a polar solvent.
US11401358B2 Method of converting ethylene to polyacrylic acid (PAA) and superabsorbent polymer (SAP) within an integrated system
Disclosed are systems and methods for the production of polyacrylic acid and superabsorbent polymers from ethylene oxidation to form ethylene oxide. Reacting the ethylene oxide with carbon monoxide to form to beta propiolactone (BPL) or polypropiolactone (PPL), or a combination thereof. An outlet configured to provide a carbonylation stream comprising the BPL or PPL, or a combination thereof and using one or more reactors to convert BPL to acrylic acid or to convert at least some of the BPL to PPL, and then to convert PPL to acrylic acid. An outlet configured to provide a PPL stream to a second reactor tm to convert at least some of the PPL to AA or a third reactor to convert at least some of the PPL to AA. The outlet configured to provide an AA stream to a fourth reactor to convert the AA to polyacrylic acid.
US11401355B2 Ethylene-vinyl alcohol copolymer, method of producing ethylene-vinyl alcohol copolymer, resin composition, and multilayer structure
An ethylene-vinyl alcohol copolymer has an ethylene content of 20 to 60 mol % and includes a carboxylic acid group and a lactone ring group present at terminals thereof, wherein the molar concentration (Y/Z) of a lactone ring molar content (Y) to a sum (Z) of a carboxylic acid molar content (X) and the lactone ring molar content (Y) is not less than 58 mol %. The ethylene-vinyl alcohol copolymer is excellent in high-temperature thermal stability substantially without thermal decomposition, and is free from odor emanation and coloration even if being processed at a higher temperature.
US11401354B2 Bis-biphenyl-phenoxy catalysts for olefin polymerization
Embodiments are directed to a catalyst system comprising metal ligand complexes and processes for polyolefin polymerization using the metal ligand complex having the following structure:
US11401353B2 Photocurable compositions for stereolithography, method of forming the compositions, stereolithography methods using the compositions, polymer components formed by the stereolithography methods, and a device including the polymer components
A photocurable composition for stereolithographic three-dimensional printing, wherein the photocurable composition comprises a photoreactive oligomer component comprising a hydrophobic oligomer comprising a photoreactive end group, a photoreactive monomer component comprising a photoreactive monomer having a photoreactive end group, and a photoinitiation composition comprising a photoinitiator; the photocurable composition has a viscosity of 250 to 10,000 centipoise at 22° C., determined using a Brookfield viscometer; and the photocured composition has a dielectric loss of less than 0.010, preferably less than 0.008, more preferably less than 0.006, most preferably less than 0.004, each determined by split-post dielectric resonator testing at 10 gigahertz at 23° C.
US11401351B2 Method of producing a rubbery polymer
A method for producing a rubbery polymer includes a step of preparing a mixture containing an alkyl (meth)acrylate, a hydrophobe, and an emulsifier, wherein an amount of the hydrophobe is 0.1-10 parts by mass relative to 100 parts by mass of the alkyl (meth)acrylate, and an amount of emulsifier is 0.01-1.0 part by mass relative to 100 parts by mass of the alkyl (meth)acrylate; a step of applying a shear force to the mixture to prepare a pre-emulsion, and a step of heating the pre-emulsion to polymerize the resulting mixture by miniemulsion polymerization.
US11401349B2 Single linker FabFv antibodies and methods of producing same
The present disclosure relates to a multi-specific antibody molecule comprising or consisting of three polypeptides: a) a polypeptide chain of formula (I):(Vxx)nVx-Cx-X-V1; and b) a polypeptide chain of formula (II): (Vyy)nVy-Cy c) a polypeptide of formula (III):V2 wherein Vx represents a variable domain, Vxx represents a variable domain, Cx represents a constant region, X represents a linker, V represents a variable domain, Vy represents a variable domain, Vyy represents a variable domain, Cy represents a constant region, V2 represents a variable domain, nindependently represents 0 or 1, wherein the polypeptide chain of formula (I) and the polypeptide chain of formula (II) is aligned such that the constant regions Cx and Cy are paired and the variable domains Vx and Vy are paired to form a binding domain and optionally a disulphide bond is present between V1 and V2, in particular where a disulphide bond is present. The disclosure also extends to pharmaceutical formulation comprising the construct, DNA encoding the constructs and vectors comprising same. The disclosure further extends to a method of expressing the constructs, for example in a host cell and methods for formulating same as a pharmaceutical composition. The disclosure also relates to use of the constructs and formulations in treatment.
US11401345B2 Humanized antibodies targeting human tissue factor
The present disclosure provides humanized antibodies and antibody-drug conjugates that specifically bind to human tissue factor, and which do not inhibit tissue factor mediated blood coagulation compared to a normal plasma control. Further described are methods of making and methods of using the disclosed humanized antibodies and antibody-drug conjugates in the treatment of cancer.
US11401342B2 Therapeutic molecules binding PSMA
The invention relates to improved binding molecules that bind specifically to prostate specific membrane antigen (PSMA), in particular, single human variable heavy chain domain antibodies and related methods for treatment of cancer.
US11401341B2 Recombinant monoclonal antibodies and corresponding antigens for colon and pancreatic cancers
The present invention provides for recombinant monoclonal antibodies that bind to human colorectal and pancreatic carcinoma-associated antigens, along with nucleic acid sequences encoding the antibody chains, and the amino acid sequences corresponding to the nucleic acids, and uses for these antibodies, nucleic acids and amino acids.
US11401340B2 Targeting gene amplification in cancer using triplex formation as a therapeutic strategy
Disclosed herein are methods and agents for the treatment of cancer using p53-independent apoptosis to reduce the number of p53-depleted or p53-mutated cancer cells that have amplified HER2 gene. Also disclosed herein are methods and agents for the treatment of HER2-positive cancer in individuals with Li-Fraumeni Syndrome.
US11401333B2 Anti-FGFR3 antibodies and methods using same
The invention provides FGFR3 antibodies, and compositions comprising and methods of using these antibodies.
US11401331B2 Anti-PD-L1 antibody and IL-7 fusions
Provided are fusion molecule having a PD-L1 inhibitor fused to a human IL-7 protein or fragment thereof through a peptide linker. The disclosed fusion molecules exhibited synergistic anti-tumor effects.
US11401329B2 Anti-CD47 antibodies and uses thereof
Anti-CD47 antibodies and antigen-binding fragments thereof are described. Also described are nucleic acids encoding the antibodies, compositions comprising the antibodies, and methods of producing the antibodies and using the antibodies for treating or preventing diseases such as cancer, inflammatory disease, infectious disease, atherosclerosis, cardiovascular disease, metabolic disease, radiation-induced injury, and/or autoimmune disease.
US11401323B2 Epstein-Barr virus antibodies and uses thereof
Disclosed herein are antibodies or immunogenic fragments thereof that specifically bind to Epstein-Barr virus (EBV) glycoprotein 350 (gp350) or 220 or one or more epitopes of EBV gp350 and neutralize EBV infection. Also disclosed are immunogenic peptides comprising one or more gp350 epitopes, EBV antibody-small molecule conjugates and pharmaceutical compositions comprising the antibody or an immunogenic fragment thereof, one or more epitopes of EBV gp350, one or more immunogenic peptides, or the EBV antibody-small molecule conjugate. The antibodies, epitopes, immunogenic peptides, conjugates, and pharmaceutical compositions can be used to treat or prevent EBV infections and EBV-associated conditions and diseases.
US11401321B2 Method for determining mutateable ligand-GPCR binding at single amino acid resolution and pairs of mutated ligand and GPCR
Method of determining GPCR and mutateable ligand binding ability, includes providing a well microtiter plate with well array having rows and columns, GPCR or rhodopsin in wells, and parent ligand mutant binding to GPCR when GPCR resides in conformation, contacting parent ligand mutants in wells with GPCR, coupling parent ligand to GPCR, and determining mutant ligand binding strength compared to standard parent ligand and GPCR by determining coupled mutant-GPCR complex in wells. Rhodopsin binding 403 mutants covering arrestin sequence provides functional 4th dimension arrestin crystal structures. Resulting single amino acid resolution functional maps reveal critical interactions in arrestin polar core and C-tail interrupted during activation. Amino acid patches reduce binding and act as direct binding rhodopsin interfaces. This and computational molecular docking active arrestin4 and light-activated rhodopsin develop arrestin-rhodopsin complex model. Combined mutants allow binding affinity modification and GPCR-ligand complex stability for diagnostics or intervention.
US11401318B2 Multimeric polypeptides of HLA-G including at least two alpha3 domains and pharmaceutical uses thereof
Multimeric polypeptides and pharmaceutical uses thereof; multimers of alpha3 peptides of an HLA-G antigen and methods of producing such multimers, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection. The multimers include at least two monomers, each of said monomers being selected in the group consisting of a peptide P1 of formula X1-X2, wherein X1 represents a peptidic linker including a cysteine amino acid and X2 represents an alpha3 domain of HLA-G.
US11401316B2 High avidity HPV T-cell receptors
The present invention pertains to novel high avidity antigen recognizing constructs against Human Papilloma Virus antigens. The invention provides novel T cell receptor (TCR) based molecules which are selective and specific for HPV 16/18 proteins E5, E6 and E7. The TCR of the invention, and HPV antigen-binding fragments derived therefrom, are of use for the diagnosis, treatment and prevention of HPV infection, as well as for the diagnosis, treatment and prevention of HPV infection mediated secondary diseases as HPV infection caused cancers, such as cervical, nasopharyngeal or head and neck cancer. Further provided are nucleic acids encoding the proteins of the invention, and recombinant cells expressing the same.
US11401313B2 De novo design of potent and selective interleukin mimetics
De novo designed polypeptides that bind to IL-2 receptor βc heterodimer (IL-2Rβc), IL-4 receptor αcheterodimer (IL-4Rαc), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides.
US11401312B2 Cytokine derived treatment with reduced vascular leak syndrome
The present invention relates to a pharmaceutical composition for treating a cancer or an infection in a subject by administrating an amount of an interleukin 15 (IL-15) derivative conjugate so as to induce a proliferation of natural killer cells (NK cells) which is the same or higher than the one obtained with high dose of interleukin-2 (HDIL-2); eventually associated with a pharmaceutically acceptable carrier.
US11401310B2 Peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11401306B2 HPV16 non HLA-restricted t-cell vaccines, compositions and methods of use thereof
Novel human papillomovirus immunogenic compositions and methods of use thereof are provided. The compositions comprise unique combinations of multi-epitope peptide sequences specifically selected and designed to be effectively processed and cross-presented to T-cells. The peptides utilized in the compositions display high levels of binding with HLA-supertypes. The immunogenic compositions are broadly applicable to large proportions of target populations. The compositions comprise adjuvants such as cationic lipids.
US11401303B2 Synthetic peptide BRAP and application in preparation of anti-inflammatory drug for COVID-19 thereof
A synthetic peptide brap can be used in preparing an anti-inflammatory drug for COVID-19. The amino acid sequence of a synthetic peptide brap is as shown in SEQ ID No: 1. The synthetic bradykinin receptor antagonism peptide (brap) has significant target-docking and inhibiting effects on G-protein-coupled bradykinin B1 and B2 receptors. The intranasal administration of brap has local effects on allergic nasal inflammation, and has systemic pharmacodynamic effect on pulmonary leakage, lung injury and LPS-induced cytokine storm. The intravenous injection of brap has an obvious inhibiting effect on the excessive inflammation, oxidative stress response and serious lung injury emerging in LPS-induced mice; and has an obvious inhibiting effect on the excessive release of proinflammatory factors IL-6 and TNF-α, overexpression of IL-6 mRNA, and massive generation of reactive oxygen species (ROS) in the LPS-induced inflammatory factor storm.
US11401297B2 Synthesis of glycoconjugate derivatives of a bile acid
Processes for the synthesis and purification of glycoconjugate derivatives of cholic acid of formula (I) are provided herein.
US11401296B2 Amidite compound and method for producing polynucleotide using said compound
The present invention provides an amidite compound represented by formula (1) which enables a synthesis of RNA with high purity, and the method for preparing a polynucleotide by using the same compound. (In the formula (1), wherein R represents the following formula (wherein Ra and Rb are identical to or different from each other and each represents a methyl group, an ethyl group, or a hydrogen atom, with the proviso that Ra and Rb does not represent a hydrogen atom, n is an integer of 1 to 5), and Ba represents a group containing optionally protected nucleobase structure, and G1 and G2 are identical to or different from each other and each represents a protecting group for a hydroxy group, and G3 are identical to or different from each other and each represents an alkyl group.
US11401293B2 Oligosaccharide c-glycoside derivatives
The present invention provides a novel process for preparing an oligosaccharide C-glycoside derivative of formula I, comprising reacting a compound of formula II with compound of formula III in the presence of at least one primary or secondary amine and at least one additive [in the formulae, the substituents are as defined herein], and novel oligosaccharide C-glycoside derivatives that can be prepared using the process.
US11401291B2 Compound, nanoribbon, and semiconductor device
A nanoribbon includes a structure represented by a structural formula (8), where g, p, q, r, s, t, and u are mutually independent and are integers greater than or equal to 1, R1, R2, R3, R4, R5, R6, R7, and R8 are mutually independent and are one of a hydrogen atom, a substituent, an alkyl moiety, a phenyl moiety, and a halogen atom, and A denotes a hydrogen atom or as aryl group.
US11401281B1 Synthesis of copper azido-based energetic compound
A method for synthesizing an energetic compound via direct assembly. The energetic compound being characterized by a local structure that features four crystallographically unique copper atoms bound by nine unique azide molecules and one tetrazole molecule with potassium ions to form a salt.
US11401279B2 Pyrido[3,2-d]pyrimidine compounds as immunomodulators
The present disclosure is directed to compounds of Formula (I): which modulate PD-1/PD-L1 protein/protein interaction, compositions, and methods of treating various diseases, including infectious diseases and cancer.
US11401277B2 Anti-bacterial heterocyclic compounds and their synthesis
The invention relates to compounds of Formula I and Formula (B) along with their stereoisomers, pharmaceutically acceptable salts, complexes, hydrates, solvates, tautomers, polymorphs, racemic mixtures, optically active forms, and pharmaceutically active derivatives thereof. These compounds are useful for killing or inhibiting the growth of a microorganism selected from the group consisting of bacteria, virus, fungi, and protozoa.
US11401276B2 Chromene compound, curable composition comprising the compound, and optical article including a cured body of the curable composition
A chromene compound having at least one indenonaphthopyran moiety which has a group forming a spiro ring together with the 13-position carbon atom and further an oligomer chain group selected from a polyalkylene oxide oligomer chain group having at least three recurring units and a polyester oligomer chain group having at least three recurring units, represented by the following formula and having reduced matrix dependence: wherein R1 and R2 are each a group which may have an oligomer chain group, the ring Z bonded to the 13-position carbon atom of the chromene compound is a Spiro ring group, and R3 and R4 are each an aryl group or heteroaryl group which may have an oligomer chain group. Preferably, the chromene compound has at least one oligomer chain group in the molecule.
US11401272B2 Heterocyclic compounds as LSD1 inhibitors
The present invention is directed to compounds of Formula I which are LSD1 inhibitors useful in the treatment of diseases such as cancer.
US11401270B2 Alcoxyamino derivatives for treating pain and pain related conditions
The present invention relates to new compounds of formula (I) that show great affinity and activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), or dual activity towards the subunit α2δ of voltage-gated calcium channels (VGCC) and the noradrenaline transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments.
US11401269B2 Intermediates and processes for the preparation of Linagliptin and its salts
Disclosed are new intermediates for the synthesis of Linagliptin and of its salts and a process for its preparation involving said intermediates.
US11401264B2 Heterocyclic compound
The present invention provides a heterocyclic compound having an activity to promote the maturation of a cardiomyocyte.A compound represented by the formula (I): wherein each symbol is as defined in the description, or a salt thereof has an activity to promote the maturation of a cardiomyocyte, and is useful as a cardiomyocyte maturation promoter.
US11401262B2 Dimeric contrast agents
The present invention relates to new class of dimeric macrocycles capable of chelating paramagnetic metal ions, their chelated complexes with metal ions and the use thereof as contrast agents, particularly suitable for Magnetic Resonance Imaging (MRI) analysis.
US11401261B2 2-heteroaryl aminoquinazolinone derivative
Provided is a 2-heteroaryl aminoquinazolinone derivative, which is a compound represented by formula (1): or a pharmaceutically acceptable salt thereof wherein X1 represents CR1 or N, X2 represents CR2 or N, X3 represents CR3 or N, X4 represents CR4 or N, Y represents optionally substituted C1-6 alkyl, an optionally substituted C3-10 alicyclic group, an optionally substituted 4- to 10-membered nitrogen-containing non-aryl heterocycle, optionally substituted C6-10 aryl, or optionally substituted 5- to 10-membered heteroaryl, Z represents optionally substituted 6- to 10-membered heteroaryl, and R1, R2, R3, and R4 each independently represent a hydrogen atom, halogen, cyano, optionally substituted C1-6 alkyl, optionally substituted C1-6 alkoxy, or the like.
US11401249B2 Bicyclic heteroaryl derivatives and preparation and uses thereof
The present invention relates compounds of Formula (A), as well as their preparation and uses, and further relates pharmaceutical compositions comprising these compounds and their uses as modulators of dysfunctional glutamate transmission. The present invention also relates to uses of the compounds or pharmaceutical compositions in treating or preventing certain neurological and psychiatric disorders and diseases as well as cancer in humans.
US11401248B2 Liquid-liquid extraction methods for purifying and producing pure thioflavin T by monitoring light emission intensity of thioflavin T
The present invention relates to a method for purifying pure thioflavin T having a step of preparing a thioflavin T solution in which crude thioflavin T is dissolved in a polar solvent and a step of carrying out liquid-liquid extraction of the thioflavin T solution with a non-polar solvent.
US11401247B2 Thiazole-5-carboxylic acid derivative and preparation method and use thereof
The present disclosure relates to a thiazole-5-carboxylic acid derivative represented by Formula (I), a stereoisomer and/or pharmaceutically acceptable salt thereof. The compound of Formula (I), the stereoisomer and/or pharmaceutically acceptable salt thereof of the present disclosure can be used to prepare a medicament for preventing or treating hyperuricemia and/or gout, and can be prepared into dosage forms for various administration routes. The compounds provided in the present disclosure have good tolerance, safety and excellent uric acid-lowering activity.
US11401245B2 Compositions for the treatment of pulmonary fibrosis
The present invention relates to compounds and their use in the prophylactic and/or therapeutic treatment of pulmonary fibrosis and/or related conditions.
US11401244B2 Apelin receptor (APJ) agonists and uses thereof
This disclosure is directed to agonists of the apelin receptor (APJ) and uses of such agonists.
US11401241B2 Aromatic aldehydes with sustained and enhanced in vitro and in vivo pharmacologic activity to treat sickle cell disease
Compounds and methods for preventing and/or treating one or more symptoms of sickle cell diseases (SCD) by administering at least one of the compounds are provided. The compounds are based on vanillin which is chemically modified to increase bioavailability and activity, e.g. so that the compounds bind to the F helix of hemoglobin (Hb) and prevent adhesion of red blood cells (RBCs).
US11401237B2 Composition, production method for composition, and production method for unsaturated compound
The invention relates to a composition excellent in stability during storage and stability during utilization, and relates to a method of producing the composition. The composition includes a compound (A) represented by general formula (1) and a compound (B) represented by general formula (2), and includes 0.00002 to 0.2 parts by mass of the compound (B) with respect to 100 parts by mass of the compound (A), (R1—COO)n—R2—(NCO)m  (1) (R1—COO)n—R2—(R3—R1)m  (2) wherein in general formulae (1) and (2), R1 is an ethylenically unsaturated group having 2 to 7 carbon atoms; R2 is a (m+n)-valent hydrocarbon group having 1 to 7 carbon atoms and optionally contains an ether group; R1 and R2 in the general formula (1) are the same as R1 and R2 in the general formula (2); in general formula (2), R3 is —NHC(═O)—; and n and m each represent an integer of one or two.
US11401234B2 Deuterated compounds and uses thereof
An anthraquinone compound of formula I (such as the compounds of formulae II to X) and processes for making the same are provided. Pharmaceutical compositions for use in the treatment of cancer, optionally in combination with an agent capable of reducing the level of oxygenation of a tumour, are also provided. Additionally, an option for combination with chemotherapeutic and radiotherapeutic modalities to enhance overall tumour cell kill is provided. Methods for the detection of cellular hypoxia, both in vivo and in vitro, are additionally provided.
US11401233B1 Pleuromutilin salicylic acid ester with antibacterial activity and a method of preparing the same
A compound with anti-drug resistant bacteria activity having the following formula (I): (I) is disclosed. The methods of preparing the compound of formula (I) are also disclosed.
US11401232B2 Modified chromium-doped zinc gallate nanocube, its preparation method and uses thereof
Disclosed herein are modified chromium-dpoed zinc gallate (ZGC) nanocubes, which are characterized in respectively having a concave surface that is modified with (3-aminopropyl)triethoxysilane (APTES). The modified ZGC nanocubes produce long lasting luminescence (LLL) that lasts for at least 1.5 hours under X-ray or UV excitation. Also disclosed herein are methods for the preparation of the modified ZGC nanocubes; and methods for imaging an area of interest (e.g., cancer) in a live subject using the modified ZGC nanocubes as an imaging agent.
US11401227B2 Process to produce a mono vinyl ether
A process produces a mono vinyl ether, R—O—CH═CH2. R represents an organic group with at least three carbon atoms. The process involves reacting a mono hydroxy compound. R—OH, with acetylene in presence of a catalyst to get a product mixture containing the mono vinyl ether, unconverted mono hydroxy compound, and the catalyst. To the product mixture, an ester is added that contains at least one ester group, X—O2C—. X is a hydrocarbon group containing less carbon atoms than R. The remaining mono hydroxy compound R—OH is reacted with the ester in the presence of the catalyst to get a transesterification product containing at least one ester group, R—O2C—, and an alcohol, X—OH. The mono vinyl ether is isolated from the product mixture obtained after the ester addition, optionally followed by purification of the mono vinyl ether by distillation.
US11401226B2 Systems and methods for refining cannabidiol
A method of making CBD concentrate or CBD Isolate comprises (a) milling a raw material; (b) contacting the milled raw material with an extraction solvent and separating a solid waste material to form a filtered extract; (c) concentrating the filtered extract; (d) washing the concentrated extract to form an organic phase and an aqueous phase; (e) separating the aqueous phase from the organic phase to form a washed extract; (f) removing an organic solvent from the washed extract to form a concentrated washed extract; (g) decarboxylating the concentrated washed extract; (h) vacuum distilling the decarboxylated extract to form a distillate; (i) dewaxing the distillate to form a post-dewax filtrate; (j) applying a vacuum to the post-dewax filtrate to form a post-dewax concentrate; (k) degassing the post-dewax concentrate; and (l) vacuum distilling the degassed concentrate to form a CBD concentrate.
US11401219B2 Process for producing butadiene from ethanol with in situ regeneration of the catalyst of the second reaction step
The present invention relates to a process for producing butadiene from ethanol, in two reaction steps, comprising a step a) of converting ethanol into acetaldehyde and a step b) of conversion into butadiene, said step b) simultaneously implementing a reaction step and a regeneration step in (n+n/2) fixed-bed reactors, n being equal to 2 or a multiple thereof, comprising a catalyst, said regeneration step comprising four successive regeneration phases, said step b) also implementing a regeneration loop for the inert gas and at least one regeneration loop for the gas streams comprising oxygen.
US11401217B2 Bond coatings having a silicon-phase contained within a refractory phase
A coated component, along with method of forming the same, is provided. The coated component may include a substrate having a surface, a silicon-based bond coating on the surface of the substrate, and an EBC on the silicon-based bond coating. The silicon-based bond coating may include a silicon-phase contained within a refractory phase. The silicon-phase, when melted, is contained within the refractory phase and between the surface of the substrate and an inner surface of the environmental barrier coating. Such a coated component may be, in particular embodiments, a turbine component.
US11401209B2 Binders and materials made therewith
Binders to produce or promote cohesion in non-assembled or loosely assembled matter.
US11401206B2 Substrate provided with a stack having thermal properties
A material includes a transparent substrate coated on one face with a stack of thin layers successively including, starting from the face, an alternation of three silver-based functional metal layers denoted, starting from the substrate, first, second and third functional layers respectively Ag1, Ag2 and Ag3, and of four dielectric coatings denoted, starting from the substrate, M1, M2, M3 and M4, with optical thicknesses respectively To1, To2, To3 and To4. Each functional metal layer is positioned between two dielectric coatings. The geometrical thickness of the second functional layer Ag2 is less than the thickness of the first functional layer Ag1. The geometrical thickness of the second functional layer Ag2 is less than the thickness of the third functional layer Ag3. The dielectric coating M2 exhibits a lower optical thickness To2 than the optical thicknesses To1, To3 and To4 respectively of the dielectric coatings M1, M3 and M4.
US11401203B2 Glass compositions, fiberizable glass compositions, and glass fibers made therefrom
New glass compositions and applications thereof are disclosed. Embodiments of the present invention relate to glass compositions, to fiber glass strands, to chopped fiber glass strands, to nonwoven mats of glass fibers, and to other products and methods. A fiber glass strand comprises a plurality of glass fibers comprising the glass composition of the present invention.
US11401200B2 Mixed silver powder and conductive paste comprising same
A mixed silver powder and a conductive paste comprising the powder are disclosed. The mixed silver powder is obtained by mixing two or more spherical silver powders having different properties from each other. The mixed powder may minimize the disadvantages of the respective types of the two or more powders and maximize the advantages thereof, thereby improving the characteristics of products. In addition, by comprehensively controlling the particle size distribution of surface-treated mixed silver powder and the particle diameter and specific gravity of primary particles, a high-density conductor pattern, a precise line pattern, and the suppression of aggregation over time can be simultaneously achieved.
US11401197B2 Halogen doped optical fibers
A method of forming an optical fiber preform includes: flowing a silicon halide and an oxidizer inside of a substrate tube, wherein a molar ratio of the silicon halide to the oxidizer is from about 1.5 to about 5.0; applying a plasma to the substrate tube to heat the substrate tube to a temperature of from about 1000° C. to about 1700° C.; and depositing silica glass comprising a halogen inside the substrate tube.
US11401193B2 Glass-ceramic articles with improved stress profiles
Glass-ceramic articles are manufactured by an ion exchange process that results in glass-based articles having improved stress profiles. A knee may be located at a depth of 3 microns or deeper. A compressive stress at a surface may be 200 MPa or more and at a knee may be 20 MPa or more. A non-sodium oxide may have a non-zero concentration that varies from the first surface to a depth and a depth of compression (DOC) may be located at 0.10·t, or even at 0.17·t or deeper. A two-step ion exchange (DIOX) includes, for example, a potassium bath in a first treatment to form a spike in a spike region of the stress profile, followed by a second treatment which includes, for example, a potassium and sodium mixed bath to maintain the spike and form a tail region of the stress profile. The glass-ceramic articles may thereby avoid developing a vitreous surface layer, which facilitates repeatable and reliable measurement of waveguide modes and determination of compressive stress in the surface (CS) and depth of the spike.
US11401192B2 Method for producing hollow porous quartz glass base material
One aspect is a method for producing a hollow porous quartz glass base material. Even when the hollow porous quartz glass base material is produced in large weight and high bulk density, the ease of target extraction is maintained and target extraction is performed stably. The method includes preparing a heat resistant substrate, which has an outer surface on which SiO2 particles are deposited, the outer surface having a surface roughness in which the maximum height Rz is less than 9 μm and the arithmetic average roughness Ra is less than 1 μm. The heat resistant substrate is rotated and SiO2 particles are deposited on the outer surface of the heat resistant substrate to form a glass particulate deposit. The heat resistant substrate is extracted from the glass particulate deposit to produce the base material.
US11401189B2 Gob distributor for a machine for forming glass articles
A gob distributor for a glassware forming machine includes: a housing; an arcuate or straight scoop located above the housing, having an upper end aligned at all times with an orifice of a feeder, and which radially moves so that its lower end coincides with the upper ends of straight fixed channels of a forming machine; an independent support structure connected by each scoop; at least one first shaft vertically placed within the housing to rotate on its own axis, including a first gear section; at least one second shaft horizontally or vertically placed within the housing to rotate on its own axis, including a second gear section, each first gear section and each second gear section are coupled together to form a housing gear; and at least one motor coupled at each end of each second shaft to simultaneously move the supporting structures and scoops, radially.
US11401188B2 Sludge dehydration system and sludge dehydration method
A sludge dehydration method includes a recovery process of recovering specific material as a dewatering aid from sludge generated in a sewage treatment process and a dewatering process of performing solid-liquid separation on sludge in which the dewatering aid recovered in the recovery process and dewatering target sludge are mixed.
US11401187B2 Water treatment method and water treatment apparatus
Provided are: a water treatment method that includes at least a denitrification step for denitrifying water to be treated with a denitrifying bacterium in the presence of a hydrogen donor, wherein the denitrification activity of the denitrifying bacterium can be maintained at a high level and thus the treatment speed can be increased; and a water treatment apparatus. The water treatment method includes at least a denitrification step for passing water to be treated through a biological treatment tank and denitrifying the same with a heterotrophic denitrifying bacterium in the presence of a hydrogen donor, wherein: molybdenum is added to the water to be treated to give a concentration of 0.01-1.0 mgMo/gN; a carrier is added to the biological treatment tank; and the nitrogen load to the carrier is controlled to 1.6 kgN/(m3-carrier·d) or greater.
US11401186B2 Urban river channel direct purification device
The present disclosure provides an urban river channel direct purification device. The device includes a support wall panel arranged vertically, an upper tray and a lower tray arranged horizontally, an upper end of the support wall panel is connected with the upper tray, a lower end of the support wall panel is connected with the lower tray, the upper tray and the lower tray are respectively semi-circular, several filler biological walls are disposed between the upper tray and the lower tray, a top end of each filler biological wall is fixedly connected with the bottom of the upper tray, a bottom end of each filler biological wall is fixedly connected with the lower tray, and the filler biological wall is arranged along a radial direction of the upper tray/lower tray. The device can purify the water of the river channel through the adsorption material in the device.
US11401184B1 Comparative method of maintaining a safe level of chlorine in a body of water
A method of maintaining a body of water in a usable condition through a comparative measurements of total chlorine and free chlorine in the body of water to determine if a synergistic chemical combination exists within the body of water that can effect the amount of chlorine to add to the body of water.
US11401180B2 Destruction of PFAS via an oxidation process and apparatus suitable for transportation to contaminated sites
Per- and polyfluoroalkyl substances (PFAS) are destroyed by oxidation in supercritical conditions. PFAS in water can be concentrated and prepared for destruction in a pretreatment phase. Following annihilation of the PFAS in supercritical conditions to levels below 5 parts per trillion (ppt), the water effluent can be used to recover heat, returned to sub-critical conditions, and then released back into the environment.
US11401179B2 Self-assembled surfactant structures
Stabilized surfactant-based membranes and methods of manufacture thereof. Membranes comprising a stabilized surfactant mesostructure on a porous support may be used for various separations, including reverse osmosis and forward osmosis. The membranes are stabilized after evaporation of solvents; in some embodiments no removal of the surfactant is required. The surfactant solution may or may not comprise a hydrophilic compound such as an acid or base. The surface of the porous support is preferably modified prior to formation of the stabilized surfactant mesostructure. The membrane is sufficiently stable to be utilized in commercial separations devices such as spiral wound modules. Also a stabilized surfactant mesostructure coating for a porous material and filters made therefrom. The coating can simultaneously improve both the permeability and the filtration characteristics of the porous material.
US11401177B2 Passive, gravity-driven system for treatment of an effluent in a diagnostic system
Automated systems to make target compounds from slide stainer waste streams inactive utilizing advanced oxidation processes are described herein. Advanced oxidation processes are promoted by UV irradiation and further accelerated by use of radical initiators, such as hydrogen peroxide. The automated systems further include mechanisms for segregating components of the waste streams.
US11401174B2 Desalination system
A heating system for use in the solar powered heating of water. The heating system is used in conjunction with a solar water farm to desalinate water. The water farm can be utilized on a variety of scales and can be applied to agricultural farms for large scale reclamation of deserts.
US11401164B2 Process for producing graphene foam-based sealing materials
Provided is a process for producing a solid graphene foam-based sealing material. The process comprises: (a) preparing a graphene dispersion having a graphene material dispersed in a liquid medium, which contains an optional blowing agent; (b) dispensing and depositing the graphene dispersion into desired shapes and partially or completely removing the liquid medium from these shapes to form dried graphene shapes; (c) heat treating the dried graphene shapes at a first heat treatment temperature from 50° C. to 3,200° C. at a desired heating rate sufficient to induce volatile gas molecules from the non-carbon elements or to activate the blowing agent for producing the graphene foam; and (d) coating or impregnating the graphene foam with a permeation-resistant binder or matrix material to form the sealing material.
US11401163B2 Catalytic materials for pyrolysis of methane and production of hydrogen and solid carbon with substantially zero atmospheric carbon emissions
A catalyst for the pyrolysis of a hydrocarbon, such as methane or natural gas, includes a pile of waste-product configured to facilitate the decomposition of the hydrocarbon into hydrogen and carbon. The waste-product is one of bauxite residue, mill scale, or slag. The pile of waste product may be broken down into a powder or piece-meal form.
US11401161B2 Distributed sensor system
A distributed sensor system is disclosed that provides spatial and temporal data in an operating environment. The distributed sensor nodes can be coupled together to form a distributed sensor system. For example, a distributed sensor system comprises a collection of Sensor Nodes (SN) that are physically coupled and are able to collect data about the environment in a distributed manner. For example, a first sensor node and a second sensor node is formed respectively in a first region and a second region of the semiconductor substrate. A flexible interconnect is formed overlying the semiconductor substrate and couples the first sensor node to the second sensor node. A portion of the semiconductor substrate is removed by etching beneath the flexible interconnect such that the distributed sensor system has multiple degrees of freedom that support following surface contours or sudden changes of direction.
US11401160B2 MEMS sensor detection device and MEMS sensor system
The invention discloses a MEMS sensor detection device and a MEMS sensor system, wherein the MEMS sensor detection device comprises: a readout circuit used for analog signal processing of the output signal of the MEMS sensor to generate detection voltage; a cancellation voltage generation circuit used for generating a gravity cancellation voltage according to the detection voltage, wherein the gravity cancellation voltage and the gravity acceleration are in a positive proportional relationship; a selection circuit used for selecting the detection voltage output in a feedback phase and selecting the gravity cancellation voltage output in a gravity cancellation phase, wherein in one detection period, the feedback phase is located after the gravity cancellation phase; and a feedback circuit used for generating a feedback voltage according to the output voltage of the selection circuit, wherein the feedback voltage is in a positive proportional relationship with the output voltage of the selection circuit. The MEMS sensor detection device and the MEMS sensor system disclosed by the invention can cancel the influence of gravity acceleration and improve the sensitivity of the MEMS sensor system.
US11401159B2 MEMS transducing apparatus and method of fabricating the same
A MEMS transducing apparatus includes a substrate, a conductive pad, a stacked structure of a transducing device, a first polymer layer, a second polymer layer and a third polymer layer. An upper cavity is formed through the substrate. The conductive pad is formed on a first surface of the substrate to cover a first opening of the upper cavity. The stacked structure of the transducing device is formed on the conductive pad. The first polymer layer is formed on the first surface of the substrate. A lower cavity is formed through the first polymer layer. The stacked structure of the transducing device is exposed within the lower cavity. The third polymer layer is formed on a second surface of the substrate to cover a second opening of the upper cavity. The second polymer layer is formed on the first polymer layer to cover a third opening of the lower cavity.
US11401158B2 Sensor packages
A sensor package includes a sensor, at least one external wall, and an interposer, arranged between the sensor and the at least one external wall. The sensor is wire bonded to the interposer and the interposer is wire bonded to the at least one external wall. Using an interposer, wire bonded to both the sensor and the at least one external wall, is an improved approach to electrically connecting a sensor and a sensor package. The interposer allows for short wire bonds from the sensor and the at least one external wall to the interposer, replacing the single, long wire bond from the sensor to the at least one external wall in the prior art. This provides improved resilience of the sensor package under high stress. Furthermore, it allows an existing sensor and package combination to be improved without needing to redesign either component.
US11401156B2 Micro-electro-mechanical system silicon on insulator pressure sensor and method for preparing same
The present invention discloses a micro-electro-mechanical system silicon on insulator (MEMS SOI) pressure sensor and a method for preparing the same. The pressure sensor includes a bulk silicon layer, a buried oxide layer, a substrate, a varistor, a passivation layer, and an electrode layer. The varistor is obtained by means of photolithography and ion implantation on a device layer of an SOI wafer. The passivation layer is SiO2 formed by means of annealing treatment on the SOI wafer. An annealing atmosphere is one of pure O2, a gas mixture of O2/H2O, a gas mixture of O2/NO, a gas mixture of O2/HCl, and a gas mixture of O2/CHF3. By means of the annealing treatment, the damage to a surface of the buried oxide layer as a result of over-etching during formation of the varistor by means of photolithography is eliminated and the unstability of the sensor caused by body and interface defects of the passivation layer and trapped charges thereof is resolved. A trench is formed at the buried oxide layer and the bulk silicon layer directly below the varistor, which helps overcome defects as a result of doped impurities entering the buried oxide layer below the varistor, and helps improve the sensitivity of the sensor.
US11401153B1 Manual fuel pump
A manual fuel pump device comprises a crank operated fuel pump in mechanical communication with a spring-loaded hand crank by means of a pump, pulley, and belt system. A dynamo is in mechanical communication with the belt thereby generating a useable electrical current. The device is configured to be an additional component of industry grade fuel dispenser permitting a user to operate the dispenser in the event of an electrical outage.
US11401152B2 Apparatus, system, and method of transporting fluid products
An improved apparatus, system, and method of transporting a fluid product such as milk or juice is provided. A flexible tank or bladder is used to temporarily store the raw milk or juice and/or facilitate handling of the milk/juice between the supplier (e.g., farm), processing/bottling facility, and retail facility or storage facility.
US11401143B2 Pivot locking device and lifting device having a pivot locking device
The invention relates to a pivot locking device of two bearing elements (102, 103) oriented towards a common axis, in which one or both bearing elements (102, 103) are pivotable about a common pivot axis (22), with a first bearing element (102), which comprises a perforation (104), with a second bearing element (103), which comprises a perforation (106), wherein the first and second bearing elements (102, 103) are oriented in alignment to one another with the perforations (104, 106), with a chamber (124) provided on the first bearing element (102), which chamber comprises a circulatory path for circulatory elements (129) and is open to the second bearing element (103) and, by a connecting surface (118) facing to the chamber (124), is closed on the second bearing element (103), with a plurality of circulatory elements (129) arranged in the chamber (124), with an catch (121) arrangeable on the second bearing element (103), which catch engages into the circulating chamber (124) and is positioned between circulatory elements (129) and, in a pivot movement of the second bearing element (103) to the first bearing element (102), displaces the circulatory elements (129) in the chamber (124) along the circulatory path, and with a locking element (107) arranged on the first bearing element (102), which locking element, in an unlocking position (109), unblocks the circulatory path for the circulatory elements (129) in the chamber (124) and, in a locking position (108) of the locking element (107), blocks a displacement movement of the circulatory elements (129) along the circulatory path of the chamber (124).
US11401140B1 Lifting device for pipes
A lifting device configured with a linear bearing system operatively associated with a support system configured for raising, lowering and positioning pipes for installation, service, or removal.
US11401133B2 Method of controlling a stairlift and a stairlift
A method of controlling a stairlift, the stairlift including a rail, a chair, and a drive assembly having a drive engine for driving the chair along the rail. The chair is attached to the drive assembly and the chair has an armrest, wherein the armrest is pivotably supported at the chair by a hinge. The hinge allows a rotational movement of the armrest, in particular along a vertical axis. The method includes detecting an angular position of the armrest and controlling at least one functionality of the stairlift, in particular a functionality of the drive assembly, as a function of the detected angular position.
US11401132B2 Retractable cord management system
A cord management system for a cabinet or other similar furniture, appliances, or other applications include a conduit. A cord management weight is disposed within the conduit. The cord management weight includes a cord receiving portion and a weight locking feature. The cord receiving portion is configured to receive a portion of an electrical cord of an electronic device. The weight locking feature is configured to selectively prevent translational movement of the cord management weight within the conduit. The cord management weight is configured to be selectively retracted into the conduit and locked into position within the conduit.
US11401131B2 Reel with indicator information
The reel which can mount substantial amounts of information for identifying the type of a wire wound thereon without increasing the hub size. The reel includes a hub that includes a winding part, a pair of flanges that face each other with the winding part interposed therebetween, first information display portions that are disposed on a first circumference about a shaft center of the hub of at least a surface of the flange, and a second information display portion that is disposed on a second circumference having a smaller diameter than that of the first circumference. The second information display portion is disposed in a region surrounded, in a circumferential direction, by both inner ends of the adjacent first information display portions and the shaft center of the hub.
US11401130B2 Multispool cabinet for winding a filament onto a transport spool and buffer spool for same
The subject matter of the invention is a manual multispool cabinet for winding a number of filaments (40, 40a) onto a respective removable transport spool (14, 14a) having a driven main winding shaft (10, 10a) per transport spool (14, 14a), wherein the main winding shaft (10, 10a) is formed for an exactly fitting reception of the transport spool (14, 14a, 214), and wherein the main winding shaft (10, 10a) drives the transport spool (14, 14a). Providing such a manual multispool cabinet that has such an increased filament speed is achieved in that, in addition to the transport spool (14, 14a), a buffer spool (12, 12a) is held on the main winding shaft (10, 10a).
US11401128B2 Conveyor and printer
A conveyor includes a first conveyance path along which a sheet is conveyed in a first direction, a second conveyance path along which the sheet is conveyed in a second direction different from the first direction, a switching part configured to switch a conveyance direction of the sheet between the first direction and the second direction, a sheet detector configured to detect the sheet at the switching part, a conveyance system driver configured to convey and stop the sheet, and circuitry configured to control the conveyance system driver to stop conveyance of the sheet in a predetermined condition, control the sheet detector to detect the sheet at the switching part, and control the switching part to switch the conveyance direction of the sheet from the first direction to the second direction when the sheet detector does not detect the sheet at the switching part.
US11401124B2 Media sheet skew correction
In an example of the disclosure, a driver correction specification is calculated based upon a time differential between a first sensor detection of a first portion of a leading edge of a media sheet and second sensor detection of a second portion of the leading edge. The driver correction specification is for causing skew correction of the media sheet as the media sheet moves along a media path to impact a blocker element. The driver is caused to operate according to the calculated driver correction specification.
US11401119B2 Monorail tray conveyor
A monorail tray conveyor in which a tray having magnets is driven along a single rail of a tray conveyor segment by stator coils housed in the rail. Carriage monorail segments including carriages that are driven along monorails have transfer rails that align with the rails of tray conveyor segments to transfer trays atop the carriage transfer rails between tray conveyor segments. The carriage monorail segments include horizontal translator segments, elevator segments, diverter segments, and filter segments.
US11401117B2 Device for moving a stack of products using a robot equipped gripper
A device for moving a stack of products using a robot. The robot has an articulated arm and a first gripper for the stack of products. The first gripper is disposed on the articulated arm. A gripping device is disposed on the articulated arm, the gripping device contains the first gripper and a second gripper, the first and second grippers are positionable relative to one another. Robot advantageously provides a method of moving stacks of products in an automated way and in particular of depositing them in a turned or unturned arrangement.
US11401115B2 Machine for conveying objects and multi-bay carousel for use therewith
A machine for conveying objects, including: a base; a turret mounted to the base for rotation about an axis, the turret including a turret mounted track, and a turret shuttle with a gripper to grip an object, the turret shuttle mounted on the turret mounted track; a boom mounted to the turret, whereby turret rotation sweeps the boom radially about the axis, the boom including: a boom mounted track extending therealong, a boom shuttle with a gripper to grip an object, the boom shuttle mounted to the boom mounted track, and a carousel located proximal to the base extending around the turret and rotatable about the axis, the carousel having a plurality of object bays, the carousel being controllably rotatable about the axis to locate any of the object bays proximal to the turret mounted track for transfer of an object between the object bay and the turret shuttle.
US11401111B2 Conveyor apparatus and operating method thereof
A conveyor apparatus includes a supporting plate and a conveyor module. The supporting plate is connected to the conveyor module. The supporting plate includes a first power and communication terminal that is configured to provide the conveyor module with power and a communication connection. The conveyor module is connected to the supporting plate. The conveyor module is detachable and includes a second power and communication terminal that is connected to the first power and communication terminal to receive the power and to perform the communication connection. The first and second power and communication terminals are detachable, with an ability to be connected to and disconnected from each other.
US11401102B2 System to hold multiple beverage containers
A system for holding multiple beverage containers may include a cooler or carrier with toting handles, closing tabs, and base. The base may be formed from a molded plastic, rubber or synthetic rubber material. The base may also include feet that hold the base a sufficient height from the ground. The base may have a generally conic tapering drain floor that makes up its top surface. The tapering drain floor may make draining the carrier easier by directing water toward a drain hole located in the base. Extending up from the base may be a multi-layer soft-sided wall where different layers perform different desired functions. For example, an inside layer closest to the internal cavity may be a waterproof layer, a middle layer may be an insulating layer, and an external layer may be a decorative layer.
US11401098B2 Twist ring container
An assembly having a container, one or more rings around the container, and a base which secures the rings to the container. The container may also, in some embodiments, have a solid lid or flexible lid that is secured to the container with a lid collar. The ring or rings are stacked upon one another when placed on the container. When assembled, the rings are able to freely rotate with respect to each other and the container body. The container is useful as an entertainment integrated with a drinking vessel in addition to many other useful applications.
US11401096B2 Packaging, preferably medical, and corresponding assembly of packagings
The invention provides a packaging element (2, 3) comprising two shells (21, 22, 31, 32), each shell having a margin (210, 220) defining an access opening giving access to the inside of the shell, said packaging element (2, 3) having at least a “closed” configuration in which the shells form a chamber that is substantially closed and that is suitable for receiving an article, such as a medical implant. Said packaging element (2, 3) further comprises a sealing strip (4) that extends, outside the shells (21, 22, 31, 32), over the entire length of the margins (210, 220) of the shells of the packaging element, and from one margin (210, 220) of the shell to the other margin (220, 210) of the shell in such a manner as to seal the chamber defined by the two shells. The invention also provides an assembly comprising two packaging elements received one inside the other, and the invention also provides a corresponding sealing method.
US11401094B2 Carrier for containers
A carrier for holding a plurality of container includes a plurality of panels including at least one central panel and at least one attachment panel configured to receive a portion of one or more containers of the plurality of containers. At least one end flap is foldably connected to the at least one attachment panel. The at least one central panel is for being positioned between and attached to adjacent containers of the plurality of containers.
US11401093B2 Grouped screw bunch and related method and machine for production of the same
A screw bunch includes a plurality of screws grouped together in a bunch with the enlarged head end of each screw toward a first end of the bunch and the pointed tip end of each screw toward a second end of the bunch. The screws are held together in the bunch by a band structure that extends around the bunch and that engages with the shanks of a multiplicity of the screws that are located along a perimeter of the bunch. The enlarged head ends of the screws are axially staggered. The band structure may be formed by a shrink wrap plastic band that can be separated from the bunch manually to enable individual retrieval of screws from the bunch for use. A method and machinery for production of the screw bunch is also provided.
US11401089B2 Device for and method of securing a lid to a food container
A lid is secured to a food container with the aid of one or more handles that are mounted on the lid and/or the container. An elongated, flexible, flattened, stretchable strap overlies the lid and has a plurality of enlarged openings spaced apart along the strap. Two of the openings receive the one or more handles in a secured position.
US11401088B2 Container top with removable seal
A molded article comprising a container top is disclosed. The molded article includes a threadless frame defining an opening, a flip cap located substantially coplanar with, and integrally formed with, the frame, a compound hinge between the frame and the flip cap, the hinge allowing the flip cap to rotate about the hinge to rest on top of the frame, an in-mold lidding film having a perimeter molded to the frame such that the in-mold lidding film covers the opening defined by the frame, wherein the in-mold lidding film is removable from the frame, and a pull tab, formed from the in-mold lidding film, that extends past the opening defined by the frame.
US11401086B2 Container
A package includes a container and a lid. The container may include a tamper evident feature, a child resistant feature, or both.
US11401085B2 Selectively openable closure for a container
A closure for a container, and more specifically a closure that is selectively openable and/or lockable providing, for example, one or more child resistant opening features is disclosed.
US11401079B2 Tamper evident cap
The invention relates to a tamper evident cap for removable screwing onto a fluid outlet provided on an enteral fluid source, the cap includes a tamper evident feature comprising a deflectable element configured to be momentarily deflectable in a longitudinal direction by a deflecting element provided on the fluid outlet as the cap is screwed onto the fluid outlet, and wherein the deflectable element is configured to be permanently deflected outwardly in relation to the longitudinal axis by the deflecting element as the cap is unscrewed from the fluid outlet to provide a visual indication that the cap has been unscrewed.
US11401078B2 Tethered plastic screw stopper
The present invention relates to tethered plastic stopper having a closure shell, a tamper band, and an annular ring. The annular ring is formed between a bottom weakness line separably linked through bottom bridges to the top edge of the tamper band and to the bottom edge of the annular ring and a top weakness line separably linked through top bridges to the top edge of the annular ring and to the bottom edge of the closure shell. At least one of the bottom bridges is configured to prevent disconnection of the annular ring from the tamper band and at least one of the top bridges is configured to prevent disconnection of the annular ring from the closure shell. The remaining bottom bridge and the remaining top bridge having a section exceeding at least 30% relative to the section of the bottom bridges and top bridges, respectively.
US11401076B2 Valve bag and method and system for producing a valve bag
The invention relates to a valve bag, in particular a cross-bottom valve bag, comprising a first wall and a second wall, which are joined to each other by means of side edges or side folds and by means of bottoms and which delimit a bag interior, comprising a valve, which is arranged in one of the bottoms and via which the bag interior can be filled with a filling material, and comprising venting openings in the first and/or in the second wall for venting the bag interior. At least one channel is provided on the outside of at least one wall, which channel covers the venting openings and is formed at least by two parallel fastening strips and by a cover strip, the cover strip likewise comprising venting openings, and wherein the shortest path between the parallel fastening strips along the cover strip is longer than the shortest path along the at least one wall or the cover strip, and/or the parallel fastening strips consist of stretchable material.
US11401073B2 Wooden pallet with butted deck boards and metal bracket supports
A pallet includes a base layer and a cargo layer. The cargo layer includes a pair of spaced apart end deck boards, and intermediate deck boards between the pair of spaced apart end deck boards. Each end deck board and an immediately adjacent intermediate deck board are butted against one another. Spaced apart supports are coupled between the base and cargo layers and forming a gap therebetween for receiving a lifting member.
US11401072B2 Hands-free portable printer having housing, knob and at least sensors to detect motions in different directions, while the knob is adapted to rotate for scrolling through sets of alpha-numeric characters
A touchless motion activated printer including a housing for receiving a stock of labels supported within the housing; a controller having a computer readable medium and in communications with a display, touchless input assembly, and a printer; and, a set of computer readable instructions stored on the computer readable medium adapted for receiving input from a user, printing a label, storing the label information and ejecting the label. The printer can include an input area. The printer can be in communications with one or more of IoT device, portable computer device, local area network, wide area network, local computer server, home automation system or any combination.
US11401071B2 Method, apparatus and system for attaching a label on a product
The present disclosure relates to a method of attaching a shrinkable label on at least one product wherein the shrinkable label comprises a film comprising heat shrinkable material and photothermic material, the method comprising: transporting a plurality of products on a product conveyor through an irradiation volume defined by a plurality of UV light emitters arranged sideways of the product conveyor; arranging at least one reflector between consecutive products on the product conveyor while the at least one product is being transported; controlling the UV light emitters to emit UV-light towards the shrinkable label arranged around the at least one product in the irradiation volume and towards the at least one reflector arranged between consecutive products in order for the photothermic material of the shrinkable label to heat up causing the heat shrinkable material to shrink around the at least one product.
US11401070B2 Labelling system and method
This invention relates to a labelling apparatus (1) and method for labelling different shapes, sizes and material types of packaging (3, 36) such as cardboard or plastics material boxes, plastics or other material bottles and sachets all containing medicaments being dispensed. The labelling apparatus (1) includes a conveyor means (4) having a receiving end for receiving an article (3, 36) to be labelled from a chute (2) and a discharge end for discharging the article (3, 36) once labelled to a receiving container (9), a label applicator (15) for attaching a label (29) to the article and a label securing means (25) for securely forcing the label (29) onto the article.
US11401069B1 Gas injected auto-dunnage formation within a filled and sealed container
Described are systems, methods, and apparatus for injecting dunnage into a container after an item has been placed in the container and the container has been sealed or otherwise closed. A dunnage injection apparatus is configured to penetrate a surface of the sealed container and expel gas and dunnage into an interior space of the container. The gas fills the expelled dunnage forming gas-filled pouches of dunnage that fill voids within the interior space of the container and secure and protect the item within the container.
US11401068B2 Apparatus for packing articles and comprising a device for counteracting winding up of film
Disclosed herein is an apparatus for packing articles as well as a device for counteracting winding up of film or web material for an apparatus for packing articles, the packing being formed by at least one web material conveyed over at least one pulling roller, wherein the device for counteracting winding up is disposed in relation to the pulling roller and extending at least partially around the pulling roller, whereby is achieved an easy, secure and functional device that efficiently counteracts and obviates the possibility of web material being wound around a pulling roller.
US11401065B2 Method for ease in identifying particular bundles of printed cards while packing and unpacking the bundles
A workflow process for packing and unpacking variable sized bundles of printed card signs includes providing identifiable codes that make the card signs highly visible and recognizable. Included on selected card signs is a color coded border with indexing added to each bundle in groupings to help in packing and unpacking the bundles into and from boxes. When the bundles are packed in a box on edge, both the person packing and unpacking the box can easily identify the beginning and end of each bundle and thereby limiting the time required to organize and process the bundles and reduce labor cost and errors.
US11401064B2 Air transfer bag deflator
A case packing apparatus for loading articles into a case that includes two or more airbags adapted to be positioned above the case; a vacuum reservoir positioned in fluid communication with the airbags; and a supply of compressed gas positioned in fluid communication with the airbags.
US11401059B2 System and method for framed lid
A package for retaining a food item includes a tray with a base connected to at least one sidewall. The sidewall extends away from the base to a rim to define an inner chamber. The tray is made of a fluid impermeable material to retain fluids in the inner chamber. The package also includes a shelf made of the fluid impermeable material that is removably supported in the inner chamber such that the shelf is spaced apart from the base of the tray to permit an absorbent pad to be positioned therebetween. The shelf is configured to support the food item in the inner chamber separated from the absorbent pad.
US11401056B2 Process for manufacturing capsules and associated system
Process for manufacturing a plurality of capsules containing a cosmetic product, the process including the following steps: —displacement of a support (32) through a first reservoir (44) containing a viscous material (52) designed to form the side wall, and coating of the support with a layer (56) of the viscous material; —displacement of the support through a shaping module (28) and solidification of the layer of material; —withdrawal of the support outside the shaping module, freeing an internal slot (74) defined by the layer of solidified material; —entry of at least one cosmetic product (11) from a second reservoir (80) into the internal slot; and —cut out the layer using a cutting device (68) to form the side walls of at least one capsule, and sealing of the internal spaces of capsules containing the cosmetic product by seals.
US11401054B2 Guideless resilient androgynous serial port docking mechanism
The Guideless Resilient Androgynous Serial Port (GRASP) mechanism provides an androgynous mechanical and electrical interface that can be tailored to the meet the requirements of a given application. Each mechanism is equipped with physical connections (spring pins) for both power and data transmission between modules.
US11401052B2 High-visibility impact detection system and method of preparing the same
A component equipped with a high-visibility impact detection system. The component includes a composite layer with a minimum impact energy level known to potentially cause damage to the composite layer, a high-visibility layer covering at least a portion of the composite layer, and a top layer covering the high-visibility layer. The top layer is configured to fracture, and expose the high-visibility layer, when subjected to an impact energy level greater than or equal to the minimum impact energy level known to potentially cause damage to the composite layer.
US11401048B2 Aircraft landing aid visual indicator device and method for guiding aircraft landing
Described is a visual indicator device for landing aircraft on the deck of a ship, comprising a unit for measuring the instantaneous rolling motion angle of the ship, a light projection apparatus designed to project, on a non-horizontal wall of the ship, at least a first rectilinear segment representing the horizon line.
US11401047B2 Unmanned aerial vehicle with latched net assembly
An example of a drone includes a drone chassis, a plurality of motors attached to the drone chassis and a plurality of propellers coupled to the plurality of motors. The drone also includes a net assembly mounted above the drone chassis. The net assembly includes an enclosure and a hinged portion that extends upwards from the enclosure in an open position and folds down in a closed position.
US11401044B2 Method and assistance system for detecting a degradation of flight performance
The invention relates to a method and to a device for detecting a degradation of flight performance of an aircraft that is in flight, wherein current flight status data of the aircraft that is in flight are first determined. A flight performance index is then calculated on the basis thereof. Furthermore, on the basis thereof, a nominal flight performance reference index is determined by means of a flight performance model, wherein a degradation of flight performance can be inferred by comparing the two indices.
US11401043B2 Systems and methods for mobile device enabled rotor track and balance
A handheld mobile device may be configured for use within a cockpit or cabin of an aircraft. The handheld mobile device may include a display and memory that includes an application configured to utilize the display. The handheld mobile device may also include a processor coupled to the memory. The application, via the processor, may be configured to receive aircraft-specific configuration data. The application may also receive, from a tracker module, input data corresponding to blade height and position. The application may additionally receive airframe vibration data from an accelerometer module. The application may further calculate recommendations regarding track and balance. The application may also further output, via the display, the track and balance recommendations.
US11401042B2 Vertical take-off and landing aircraft and transformation gear sets for same
A vertical take-off and landing aerial vehicle (VTOL) includes a plurality of rotors for producing lift. For each respective rotor the VTOL has an auxiliary power source (APS) and a transformation gear set (TGS) both being associated with the respective rotor, and the VTOL further includes at least one main power source (MPS). Each TGS is configured to form an outgoing power towards its respective rotor from input powers received into the TGS from the MPS and from the APS associated with the respective rotor.
US11401041B2 Hybrid electric power distribution and control for an aircraft
A power system of an aircraft includes a hybrid energy storage system with at least two energy storage subsystems each having a different power-energy density, power draw characteristics and/or dissimilar configuration. A primary power unit includes an aircraft engine coupled to an electric motor and a first generator. A secondary power unit is coupled to a second generator. A bidirectional power converter is coupled to the hybrid energy storage system and one or more controllers of the electric motor, the first generator, and the second generator. A power management controller is configured to interface with the hybrid energy storage system and the one or more controllers of the electric motor, the first generator, and the second generator and perform a model predictive control to dynamically adjust one or more electric power flows through the bidirectional power converter based on an engine propulsion power demand of the aircraft engine.
US11401030B2 Propeller blade spar
A method of manufacturing a spar for a propeller blade comprises forming a hollow inner core from a composite material, and then braiding carbon fibres around the inner core to form an outer spar structure. The hollow inner core may be formed using an inflatable bladder and a mould defining an outer shape of the spar. This construction avoids the need for a foam core to be provided within the spar.
US11401021B2 Cover for protecting rawinsonde balloon in preparing flight of rawinsonde balloon
A cover for a rawinsonde balloon includes a cover main body with an inner surface forming inner space and an outer surface. The rawinsonde balloon is inserted into the inner space of the cover main body. Further, the cover includes an inlet, positioned at a preliminary free end of the cover main body, for allowing the rawinsonde balloon to be inserted into the inner space and the cover additionally includes an inlet control member for controlling a size of the inlet and fixing a controlled size of the inlet. Furthermore, the cover includes a plurality of basic cover fixing members formed or located respectively at a plurality of basic preliminary fixed ends on the outer surface.
US11401019B2 Simulation method for two-stage plunger pressurized common rail fuel system of marine low-speed engine
An objective of the disclosure is to provide a simulation method for a two-stage plunger pressurized common rail fuel system of a marine low-speed engine. The method includes: first setting initial status parameters, such as a control step of a system model, a total time of a calculation process, and structure parameters and pressures of components; and then establishing a mathematical model of a fuel booster unit, a mathematical model of a high-pressure fuel pipe and a mathematical model of a fuel injector based on a MATLAB simulation platform, and connecting input and output parameters of the models to realize data transfer between the models. By considering one-dimensional (1D) spatial fluctuations in the high-pressure fuel pipe, the disclosure establishes a high-precision model of the fuel system, which provides an effective method for designing and calculating detailed pressures in the common rail fuel system.
US11401014B2 Tangent support tube for life raft assemblies
A life raft may comprise a border tube and a canopy support tube coupled to an outer portion of the border tube. A first orifice defined by the canopy support tube is aligned with a second orifice defined by the border tube. A diameter of the first orifice is less than a diameter of the second orifice.
US11401008B2 Inflatable watercraft
The present invention provides inflatable watercraft that are light weight, easily stowed in relatively small spaces and formed from inflatable drop stitch panels. A preferred watercraft is a boat having a bow, stern, keel and an open transom for self-bailing. A deck can be provided as a separate panel that is either permanently, or detachably, connected to freeboard sides of the watercraft. When connected, the deck provides a sitting area, and enhances the strength and rigidity of the watercraft by functioning like a deck beam. Optional features include a bucket held in place by, and fitted through, a hole in the deck panel. Preferred inflation pressures are between 2 and 25 p.s.i., and more preferably between 12 and 18 p.s.i.
US11401007B2 Hydraulic device
A hydraulic device is provided for a human powered vehicle. The hydraulic device includes a piston, a base member, and a hydraulic cylinder. The base member is made of a first non-metallic material. The hydraulic cylinder is provided to the base member and defines a cylinder bore. The hydraulic cylinder includes a main portion in which the piston is movably arranged. The main portion is made of a second non-metallic material that is different from the first non-metallic material.
US11401004B2 Electric motor, drive, and assembly for tracked vehicle, such as a snowmobile
An electric motor, drive, and assembly for a tracked vehicle. The assembly including an electric motor, a cylindrical housing encircling the electric motor and adapted for rotation about the motor, and a drive sprocket. The drive sprocket is coupled to the housing and having teeth to generally engage a track of the tracked vehicle.
US11400998B2 Traveling vehicle
A traveling vehicle includes a vehicle body, a left swing part, a right swing part, a holding body, and a suspension device. The left swing part rotatably supports a left front wheel. The right swing part rotatably supports a right front wheel. The left swing part and the right swing part are supported on the vehicle body. The holding body for supporting the suspension device is formed in a U-shape so as to sandwich the suspension device in a front-back direction. A support shaft provided in the suspension device is supported on the holding body on both sides in the front-back direction. The suspension device is rotatable about the support shaft. The suspension device is arranged at a position higher than the left swing part and the right swing part, and extends and contracts in conjunction with swings of the left swing part and the right swing part.
US11400995B2 Bicycle computer
A bicycle computer for monitoring performance of a user of a bicycle includes a processing circuitry; a user interface; an attaching unit for arranging the bicycle computer in an attached position; and at least one integrated proximity sensor arranged and dimensioned to measure, in the attached position, proximity data being indicative of a distance to a body part. The processing circuitry is configured to obtain the proximity data from the at least one integrated proximity sensor and to process the proximity data into one or more cycling metric. The user interface is configured to output the one or more cycling metric.
US11400993B2 Footrest arrangement for a motorcycle
A footrest arrangement is for a motorcycle, wherein the footrest arrangement comprises at least two or more individually pivotable footrest devices with footrest surfaces placed with an internal spacing between them so a motorcycle rider can choose whether to rest his foot on one or more of the footrest surfaces simultaneously.
US11400988B2 Upper wheel deflector panel
A laterally extending aerodynamic deflector panel disposed upstream in front of an otherwise exposed uppermost portion of a vehicle wheel assembly, and arranged to divert headwinds from otherwise impinging upon drag-magnified uppermost wheel surfaces to thereby minimize overall vehicle drag.
US11400987B2 Slide rail assembly and landing gear assembly with embedded hardpoint connectors
A cargo vehicle is disclosed having a composite floor assembly with at least one embedded hardpoint connector. The composite floor assembly may comprise a plurality of transverse beams, wherein a subset of the plurality of transverse beams includes at least one embedded hardpoint connector. The embedded connector may be used to securely and removably couple other vehicle components to the composite floor assembly, such as a landing gear assembly and/or a slide rail assembly.
US11400986B2 Body for vehicle
A body for a vehicle configured for securing safety performance and vehicle rigidity according to a vehicle collision while increasing a battery capacity mounted in the vehicle, may include an internal side member mounted on a top surface of a center floor in a longitudinal direction of the body; a battery cross member mounted in a width direction of the body inside a battery case provided at a lower end portion of the center floor while intersecting the internal side member; and a coupling structure coupled to the battery case, the battery cross member, and the center floor at a point where the internal side member and the battery cross member intersect.
US11400984B2 Vehicle body side part structure
In a vehicle body side part structure, a front pillar has a pillar inner panel and a pillar outer panel. A side sill has a sill inner panel and a sill outer panel. A sidewall and a front wall of the pillar outer panel on an inner side in a vehicle width direction extend to a position at which the sidewall and the front wall overlap the side sill in an upward/downward direction. A defective section is provided on a front section of the sill outer panel. A reinforcement plate extending in a vehicle upward/downward direction is coupled to a rear region of an inner side surface of the pillar outer panel. A lower end of the reinforcement plate extends to a position at which the lower end overlaps the defective section in the upward/downward direction on a side behind the defective section. A lower edge portion of the sidewall of the pillar outer panel is joined to a sidewall of the sill outer panel on an outer side in the vehicle width direction.
US11400983B2 Vehicle lower section structure
A vehicle lower section structure includes a battery unit that is disposed below a floor panel, a sliding door that is provided to a side section of a vehicle body, and a lower hinge that is attached to a lower portion of the sliding door, that supports the sliding door with respect to the vehicle body such that the sliding door is capable of sliding in a vehicle front-rear direction, and that is disposed further toward a vehicle upper side than the battery unit.
US11400982B2 Methods of making monocoques of land vehicles using modular mold systems
Land vehicles, modular systems for forming monocoques of land vehicles, and methods of forming monocoques of land vehicles using modular systems are disclosed. In certain embodiments, the land vehicles are provided as delivery vehicles and/or utility vehicles. A land vehicle includes a monocoque supporting a plurality of wheels to permit movement of the vehicle relative to an underlying surface in use of the land vehicle.
US11400980B2 Rib-less hoist structure for truck body
A hoist structure for a body of a truck can be comprised of a hoist plate arrangement extending in a first direction and configured to be rotatably coupled to a hoist member of the truck; and a plurality of external gussets spaced from each other in the first direction and extending in a second direction perpendicular to the first direction. Each of the external gussets can interface with the hoist plate arrangement, and a portion of each of the external gussets can extend in the second direction from a first side of the hoist structure arrangement.
US11400978B2 Vehicle control apparatus and vehicle control method
Provided are a vehicle control apparatus and a vehicle control method, a vehicle control apparatus including: a sensor configured to sense at least one of a vehicle speed value and a lateral acceleration value of a vehicle; an active camber device including a knuckle for supporting a wheel of the vehicle, an upper arm having one end rotatably connected to the knuckle to form a stroke node, and a actuator for rotationally shifting the stroke node of the upper arm with respect to a connection point with the knuckle in a vertical direction; and a controller configured to vary a position of the stoke node of the upper arm through the actuator on the basis of one of the sensed vehicle speed value and the sensed lateral acceleration value.
US11400977B2 Vehicle guidance system
A system and method for guiding an articulated vehicle having at least a first section and a second section includes one or more sensors positioned separately from the vehicle and adapted to detect the positions of and the angle between the first and second sections. The system also may include one or more position sensors located on the vehicle. A computing system that may be on the vehicle or positioned separately from the vehicle receives the position data and includes a pose-determining algorithm for determining the position and orientation of the vehicle and a guidance-determining algorithm for determining guidance commands to guide the vehicle to a target position. A communications device communicates the guidance commands or sensed position and/or angle information to the vehicle.
US11400976B2 Steering wheel angle calibration
A first distance d1 between a vehicle at a first location and an object is determined. A best fit line representing the object is determined from a plurality of sensor data. A distance Δd to move to a second location is specified. A predicted second distance dp between the vehicle at the second location and the object is determined based on the first distance d1, the distance Δd, and the best fit line. The vehicle is operated from the first location to the second location based on a center steering wheel angle. A measured second distance d2 between the vehicle at the second location and object is determined. Then the center steering wheel angle is one of (a) maintained based on the predicted second distance dp matching the measured second distance d2, or (b) updated based on the predicted second distance dp being different than the measured second distance d2.
US11400974B2 Towing assist device for notifying driver of backup conditions
A towing assistance device includes an acquirer, a determiner, and a notifier. The acquirer acquires a coupling angle between a towing vehicle and a towed vehicle. The determiner determines whether the towed vehicle is movable backward in a coupling posture with the coupling angle maintained, when the towing vehicle is moved backward at a current steering angle. The notifier issues information on a steering angle at which the towed vehicle is movable backward in the coupling posture, among selectable steering angles of the towing vehicle.
US11400972B2 Work vehicle
A work vehicle includes a hydraulic actuator that changes an actual steering angle, an actual steering angle detecting part, an operating unit that performs a steering operation, a position adjusting control part that controls the position adjusting part based on the actual steering angle, and a steering control part that controls the hydraulic actuator. The operating unit includes a support part, a rotating part supported rotatably by the support part, an operating part supported rotatably by the support part or the rotating part, a biasing part that biases the operating part to a predetermined position with respect to the rotating part, a position adjusting part that adjusts a rotation angle of the rotating part with respect to the support part, and a rotation angle detecting part configured to detect the rotation angle of the operating part with respect to the support part or the rotating part.
US11400970B2 Steering system
A steering system includes a mechanism configured to turn a steer wheel of a vehicle, a motor configured to generate driving force that is applied to the mechanism, and a controller configured to control the motor according to a steering status. The controller includes a limiting control circuit configured to limit a current that is supplied to the motor to a limiting value, a determining circuit configured to determine whether the steer wheel is in contact with an obstacle by using at least a comparison between a value of the current that is supplied to the motor and a threshold, and a threshold computing circuit configured to compute the threshold that is used by the determining circuit, the threshold computing circuit being configured to compute a value less than the limiting value according to the limiting value as the threshold.
US11400969B2 Center take off rack and pinion steering system
A center take off rack and pinion steering system is disclosed having a rack housing which houses a rack gear having first and second ends extending through the housing. A pinion gear is coupled to the rack gear to input steering power to the rack gear. A rack yoke is coupled to, and extends between, the first and second ends of the rack gear. A yoke support is coupled to the rack housing and a yoke support slider is coupled to the rack yoke and is movable with the rack yoke relative to the yoke support. Tie rod end mounts are supported by the rack yoke, the tie rod end mounts positioned laterally intermediate the first and second ends of the rack gear.
US11400966B2 Handcart
A handcart may include a support frame, an actuator, a rotating frame configured to be rotated relative to the support frame by the actuator and a container configured to be rotated relative to the support frame. The container may be configured to be rotated with the rotating frame relative to the support frame when the rotating frame is rotated relative to the support frame by the actuator. The rotating frame may be rotatable up to a position at which an angle between the support frame and the rotating frame becomes a first rotation angle. The container may be rotatable up to a position at which an angle between the support frame and the container becomes a second rotation angle, the second rotation angle being greater than the first rotation angle.
US11400964B2 Route examining system and method
A route examining system includes first and second detection units and an identification unit. The first and second detection units are configured to be disposed onboard a vehicle system traveling along a route having plural conductive tracks. The first and second detection units are disposed at spaced apart locations along a length of the vehicle system. The first and second detection units are configured to monitor one or more electrical characteristics of the conductive tracks in response to an examination signal being electrically injected into at least one of the conductive tracks. The identification unit includes one or more processors configured to determine that a section of the route includes an electrical short responsive to the one or more electrical characteristics monitored by the first and second detection units indicating that the examination signal is received by only one of the first and second detection units.
US11400951B2 Control system for a motor vehicle, motor vehicle, method for controlling a motor vehicle, computer program product and computer-readable medium
A control system for a motor vehicle, including a first control unit for controlling a first function of the motor vehicle, a second control unit for controlling a second function of the motor vehicle and a backup control unit. To ensure the proper execution of functions controlled of a motor vehicle controlled with the aid of control units even in the case of a defective control unit with preferably little additional effort, the backup control unit is configurable depending on the input of an error signal of the first or second control unit such that an actuator corresponding to the defective control unit is controllable with the aid of the backup control unit. A first backup power electronic module is assigned to the first actuator, and a second backup power electronic module is assigned to the second actuator.
US11400950B2 Abnormal data collecting method, apparatus, storage medium and product for automatic parking
The present application discloses an abnormal data collecting method for automatic parking, an apparatus, a storage medium and a product, and relates to automatic driving technology and automatic parking technology in computer technology. A specific implementation i: in response to monitoring that a target vehicle generates a fault code during an automatic parking process, matching the fault code with at least one pre-configured fault code to be collected; in response to determining that the fault code matches the fault code to be collected, determining a data collecting strategy corresponding to the fault code to be collected; and performing a data collecting operation on abnormal data corresponding to the fault code according to the data collecting strategy.
US11400948B2 Method for controlling vehicle functions
A method for controlling vehicle functions to increase the well-being and/or to increase the attention of at least one vehicle user in a vehicle. A number of vehicle functions are activated when at least one specific user menu is selected. Here, a lead function assigned to the user menu from the number of vehicle functions is predetermined in each case and the time and content processes of the other vehicle functions assigned to the user menu are coordinated with respect to the lead function.
US11400946B2 Method for managing a powertrain of a motor vehicle
A method for managing a powertrain (3) of a motor vehicle (1) comprises the following steps: (a) determining a predictive rolling resistance coefficient (Crr) for at least one tyre (10) of the motor vehicle (1); and (b) adapting the operation of the powertrain (3) according to the predictive rolling resistance coefficient (Crr) in order notably to optimize the energy consumption of the motor vehicle (1).
US11400941B2 Moving body behavior prediction device
A moving body behavior prediction device predicts the behavior of a moving body comprising: a travel environment recognition unit that acquires external information DS and recognizes the travel environment; a prediction model evaluation value storage unit that stores an evaluation value for each travel environment in relation to prediction models prepared in advance; a prediction model determination unit 112 that determines the prediction model corresponding to the travel environment recognized by the travel environment recognition unit from among the prediction models, the determination being performed on the basis of the travel environment recognized by the travel environment recognition unit and the evaluation value stored in the prediction model evaluation value storage unit; and a behavior prediction unit 113 that predicts the behavior of the moving body using the prediction model determined by the prediction model determination unit.
US11400940B2 Crosswind risk determination
Real-time wind data for a location is determined based on a detected movement of an object relative to a vehicle. The real-time wind data includes a wind speed and a wind direction. Upon receiving stored wind data for the location from a remote computer, a crosswind risk is determined based on the real-time wind data and the stored wind data. A vehicle component is actuated to compensate for the crosswind risk.
US11400939B2 Four-wheel drive vehicle
A four-wheel drive vehicle includes: a drive-power distribution device for transmitting a drive power of an engine toward main and auxiliary drive wheels, at a drive-power distribution ratio between the auxiliary drive wheels and the main drive wheels; and a control apparatus for executing a drive-power distribution control for adjusting the drive-power distribution ratio, and executing an engine automatic-start control for causing the engine to be started upon satisfaction of an engine-start condition. Upon execution of the engine automatic-start control, the control apparatus changes a target engine rotational speed from a predetermined engine-start rotational speed to a changed engine rotational speed, such that a difference of the changed engine rotational speed from a resonance rotational speed that causes resonance of a drive system to which the engine is connected in a power transmittable manner, is larger than a difference of the predetermined engine-start rotational speed from the resonance rotational speed.
US11400938B2 Method for controlling a drivline of a vehicle
The disclosure relates to a method for controlling a driveline (10) of a vehicle (1), wherein the driveline (10) at least comprises a transmission (13) and a clutch (12), wherein the clutch (12) is adapted to be provided between the transmission (13) and a propulsion unit (11) of the driveline (10), wherein the method comprises the steps of; predicting an imminent drive route, identifying if the imminent drive route comprises any clutch severity classification (CSC), and if the imminent drive route comprises a clutch severity classification (CSC)—estimating (103) an expected clutch temperature (Tic) dependent on at least the clutch severity classification (CSC) and one vehicle parameter (Vp), wherein, the clutch severity classification (CSC) is at least dependent on an inclination of the imminent drive route, and if (105) the expected clutch temperature (Tic) is above a clutch temperature threshold value (Tt); controlling (106) the driveline (10) in a critical heat mode, wherein in the critical heat mode the transmission (13) is controlled such that a clutch temperature increase is lower in comparison to a normal driveline control mode.
US11400936B2 Travel assistance device
A travel assistance device configured to execute travel assistance when a plurality of vehicles form a vehicle group and travel in a line. The travel assistance device includes: a first control unit configured to, if there is lane-change instruction for the vehicle group, cause an end-of-line vehicle to change lanes, such vehicle being the vehicle from among the plurality of vehicles forming the vehicle group that is positioned at the end of the line; and a second control unit configured to, following the lane change of the end-of-line vehicle, allow a lane change for at least one vehicle that is other than the end-of-line vehicle and that is one of the vehicles forming the vehicle group.
US11400935B2 Method for a motor vehicle to select a preferred traffic lane to cross a toll area
A method for a motor vehicle to select a preferred traffic lane to access a toll area having a plurality of traffic lanes includes the following: a) detecting traffic lanes of the toll area, b) determining, for at least some of the traffic lanes, a first item of data relating to the distance between the motor vehicle and the corresponding traffic lane, and a second item of data relating to the number of other vehicles situated on the corresponding traffic lane, c) minimizing a cost function that depends on each first item of data and on each second item of data, so as to identify the preferred traffic lane, and d) determining the possibility or the risk for the motor vehicle of changing traffic lane in order to move towards the preferred traffic lane.
US11400934B2 Systems and methods for cooperative ramp merge
Systems and methods for cooperative ramp merger are described herein. In one embodiment, a system for assisting with a merge based on a ramp location of a ramp is provided. A swarm module causes a host vehicle to join a swarm created to assist the merging vehicle in the merge maneuver. A position module identifies relative positions of the host vehicle and other members of the swarm. An identification module selects a role for the host vehicle based on the relative positions of the host vehicle and the other members of the plurality of members. A constraint module calculates a merge location area based on the relative positions of the host vehicle and the other members of the plurality of members and the ramp location. A cooperative module determines a cooperative action for the host vehicle based on the role of the host vehicle and the merge location area.
US11400929B2 Method and apparatus for vision based lateral acceleration prediction
The present application relates to a method and apparatus including a sensor for detecting a first vehicle speed, a camera operative to capture an image, a processor operative to determine a road curvature in response to the image, the processor further operative to determine a first predicted lateral acceleration in response to the road curvature and the first vehicle speed, the processor further operative to determine a second vehicle speed in response to the first predicted lateral acceleration exceeding a threshold value wherein the second vehicle speed results in a second predicted lateral acceleration being less than the threshold value, and to generate a control signal indicative of the second vehicle speed, and a vehicle controller operative to reduce a vehicle velocity to the second vehicle speed in response to the control signal.
US11400925B2 Planning for unknown objects by an autonomous vehicle
Among other things, a model is maintained of an environment of a vehicle. A hypothetical object in the environment that cannot be perceived by sensors of the vehicle is included in the model.
US11400916B2 Mild hybrid vehicle and method of controlling the same
A mild hybrid vehicle and a method of controlling the same are provided. The mild hybrid vehicle includes a sensor that detects shift intention of a driver to provide the shift intention as sensing information, a controller that determines a target rotation speed of an MHSG based on the sensing information and controls the MHSG based on the target rotation speed, and the MHSG that controls the rotation speed of the engine under control of the controller when the shift intention is detected.
US11400912B2 Coasting management control of a vehicle with a road speed governor
A system, method, and apparatus includes management of coasting during operation of a vehicle having an engine that is selectively engageable to a driveline, a cruise control mode of operation, and a road speed governor mode of operation. A road speed governor mode of operation of the vehicle is active in response to a road speed governor operation condition being present wherein the driveline is engaged with the engine. When a coasting management condition is present, operation of the vehicle in the road speed governor mode is disabled, the driveline is disengaged from the engine, and the vehicle is operated in a coasting mode of operation. The coasting mode of operation can be canceled when a coasting mode of operation cancellation condition is present to operate the vehicle in a road speed governor mode of operation with the driveline re-engaged with the engine.
US11400910B2 Vehicle
A vehicle includes a vehicle cabin, a storage chamber, and a partition wall separating the storage chamber from the vehicle cabin. The storage chamber is arranged on at least one side of the vehicle cabin in the vehicle front-rear direction. The partition wall has an opening and the storage chamber communicates with the vehicle cabin via the opening. A cover configured to open and close the opening is provided over the opening. A brake fluid pressure generation device is stored in the storage chamber. The brake fluid pressure generation device includes a reservoir tank in which hydraulic fluid is accumulated and is arranged at a position facing the opening.
US11400909B2 Parking brake apparatus for vehicle
A parking brake apparatus for a vehicle includes a driving unit including a plurality of motor sections; a pair of pressing units receiving power from the driving unit and pressing a brake pad; and a load transmission unit installed between the pair of pressing units, connected to each of the pair of pressing units, and transmitting a pressing load of any one of the pair of pressing units to the other pressing unit.
US11400901B2 Method for operating a vehicle, vehicle
A method for operating a vehicle, the vehicle including at least one friction brake unit, including a brake body and at least one brake element, the brake body being rotatably fixedly connected to a wheel of the vehicle and the brake element being situated on the chassis side and being displaceable in the direction of the brake body. The brake element is pressed against the brake body for generating a friction braking action, and an actual vehicle parameter resulting from the friction brake action being monitored for vibrations with the aid of at least one sensor unit. When detecting a vibration, the frequency of the vibrations is compared with the rotational speed of the wheel, and at least one safety measure is carried out in a third step if the comparison indicates that the frequency is equal to or greater than the rotational speed of the wheel.
US11400896B2 Vehicle
Provided is a vehicle including: a brake pedal configured to be able to operate a foot brake device; an accelerator pedal located on a right side of the brake pedal; a shift lever; a steering wheel; and a handbrake device which includes a brake lever extending in a front-rear direction and a grip provided at a rear end of the brake lever, and is configured to be able to manually operate and release a parking brake by a parking brake device. The handbrake device supports the brake lever so that the grip is movable between a first position at which the parking brake is released and a second position at which the parking brake is operated. The second position is set to a position at which the grip is recognized upon a start operation with any one of the accelerator pedal, the shift lever, and the steering wheel.
US11400895B2 Wiper arm device with at least one detachable auxiliary nozzle unit
A wiper arm device with at least one duct connecting unit (10) for connecting at least two wiper fluid duct sections to each other, with at least one duct retaining unit (14) which can be arranged on at least one wiper arm (12) and is configured in order to retain at least the duct connecting unit (10) on the wiper arm (12) and with at least one auxiliary nozzle unit (16). The wiper arm device has a connecting unit (18) which is configured in order to connect the at least one auxiliary nozzle unit (16) detachably to the duct connecting unit (10), in particular non-destructively.
US11400893B2 Wiper frame
Disclosed is a wiper frame (10) comprising a resilient support rail (22) and a wiper blade (12) which is attached to the support rail (22). According to the invention, the wiper blade (12) has a wiper blade lip (44) having a substantially rigid cross-sectional structure, and the wiper blade lip (44) is mounted between a first bending region (32) and a second bending region (34) in a cross-sectional view.
US11400891B2 Wiper control device
A wiper control device that properly detects restriction of a wiper blade according to a travel distance of the wiper blade. When a state in which a rotation speed of an output shaft calculated from a rotation angle of the output shaft detected by a rotation angle sensor is equal to or slower than a speed threshold defined according to a travel distance of the wiper blade and in which a current detected by a current detector is equal to or larger than a current threshold continues for a predetermined determination period, a microcomputer stops a wiper motor or reverses a direction of a wiping action of the wiper blade.
US11400889B2 UWB ranging device, personal communications device incorporating such a device, and methods of operating the same
An ultra wide band, UWB, ranging device is disclosed comprising: an input for receiving data directly from a sensor hub, and a radio configured for UWB communication; wherein the UWB device is configured to: commence a ranging process comprising at least one of a repeated range determination, and a repeated angle of arrival determination; receive sensor data from the sensor hub; process the data, and modify the ranging process in dependence on the data. Personal communication devices disclosing such UWB ranging devices are also disclosed as are associated methods.
US11400888B1 Commercial vehicle access control system
A commercial vehicle access control system provides selective access to authorized users to interior areas of respective service vehicle item storage compartments. The compartments are usable to house items such as tools, equipment, materials or products that are removed from or placed in such compartments. A system controller is in operative connection with a plurality of electrically actuated door locks which can be operated responsive to communication with a portable wireless device to enable access to selected compartments and the items which are housed therein. A plurality of vehicle cameras and other sensors are operative to detect activities related to the removal from or placement of items within the compartments, as well as other conditions associated with the operation and status conditions of the vehicle.
US11400885B2 Compact, lightweight and reusable local energy absorbers
An energy absorbing structure includes a base, a loading platform, a pair of side supports, a center support, and a pair of flexible segments. The loading platform is spaced apart from the base. The side supports project from the base toward the loading platform. The center support projects from the loading platform toward the base. The flexible segments extend from the side supports to the center support and connect the side supports to the center support. The flexible segments have straight edges and curved surfaces disposed between the straight edges. The straight edges extend from the side supports to the center support and are oriented at an oblique angle relative to the base. Each of the curved surfaces faces one of the base and the loading platform.
US11400880B2 Roof airbag for a vehicle
A roof airbag for a vehicle including deployment guides configured to extend in forward and backward directions of a vehicle and disposed to be spaced laterally apart from each other, an inflator located between the deployment guides spaced apart from each other and configured to discharge gas therefrom during operation thereof, and a cushion located between the deployment guides spaced apart from each other, deployed in an extension direction of the deployment guides and including a deployment chamber configured to be deployed while the gas discharged from the inflator flows thereinto and delay chambers configured such that the gas flows thereinto in a deployed state thereof.
US11400875B2 Holder and wire harness
A holder configured to be fitted to a tube that is made of metal and through which a wire is to be inserted, the holder including: a tubular main body that includes a first end and a second end opposite to the first end, and is configured to be inserted into the tube; and a cover formed protruding radially outward from an outer circumferential surface of the main body at the first end, wherein: the cover is formed only in a portion of the main body in a circumferential direction, and the cover includes a wall that protrudes radially outward from the outer circumferential surface of the main body, and a guard that extends from a radially outward end of the wall toward the second end of the main body.
US11400872B1 Heat shield assembly for exhaust treatment system
A heat shield system for shielding sensors from heat includes a sleeve portion made of heat-insulating material and has a hollow shape sized and shaped to be wrapped about a pipe of the exhaust treatment system. The sleeve has a longitudinal slit and an opening formed through the sleeve. The opening is configured to receive a sensor. The system includes a collar portion made of heat-insulating material and includes a base part configured to attach to the sleeve portion and a collar enclosure that extends radially from the base part. The collar enclosure defines an open chamber configured to surround the sensor and shield the sensor from heat while permitting access to the sensor. A closure is configured to retain the collar portion on the sleeve portion and hold the heat shield system in place.
US11400871B2 Metal retention clip
A retention clip is configured to securely connect a first component to a second component. The retention clip includes a first frame connected to an opposed second frame by a central beam. An interior of the clip is defined between the first and second frames. Each of the first and second frames includes lateral legs that fold inwardly at upper bends, thereby forming flanges that are disposed within the interior. The flanges on respective sides of the clip are integrally connected by a bridging member, and the flanges further include distal ends that extend below a bottom edge of the bridging member. The clip further includes a flexible wing for securing the clip within the interior of a panel opening. Some embodiments of a retention clip include protrusions that extend inwardly from the bridging members.
US11400863B2 Hitch step
The present invention relates to a hitch step that may be secured to a hitch receiver tube and which may support extremely heavy loads thereon.
US11400862B2 Vision-based interactive control apparatus and method of controlling rear-view mirror for vehicle
The present application discloses a method of controlling a rear-view mirror for a vehicle. The method includes determining a gaze position and a gaze direction of a user; and controlling the rear-view mirror based on the user's gaze position and gaze direction.
US11400860B2 CMS systems and processing methods for vehicles
A image detection and classification system for a vehicle includes a first display, a second display, an image capturing unit for capturing an image and displaying the image on at least one of the first display and the second display, and an image processing unit configured to process the captured image to improve a clarity of the captured image in response to the captured image having an obstruction value exceeding a threshold obstruction value. A method for operation of the image detection and classification system is also described.
US11400857B2 Method for operating a high-beam assistance system of a motor vehicle
A high-beam assistance system of a motor vehicle determines whether or not an unseen vehicle with headlamps switched on is approaching from the opposite direction before the unseen vehicle enters the field of view of a camera in the host vehicle. Wherein the registered images do not include any approaching vehicle on the roadway, the high-beam assistance system determines an expected illumination information item which is estimated to result from illumination by the host headlamps, determines an actual illumination information item contained in the registered images, and compares the expected illumination information item and the actual illumination information item. If the actual illumination information item deviates from the expected illumination information item, then the illumination provided by the host headlamps is adjusted from a high-beam state to a low-beam state.
US11400855B2 Integrated tailgate cargo system for automotive vehicle
Various disclosed embodiments include systems for securing cargo to a dropdown tailgate of an automotive vehicle, systems for securing a bicycle to a dropdown tailgate of an automotive vehicle, and systems for securing cargo to a tailgate of an automotive vehicle. In an illustrative embodiment, a system for securing cargo to a dropdown tailgate of an automotive vehicle includes: a dropdown tailgate including a first elongated groove running along an inner panel of the dropdown tailgate; a first securing member, the first securing member including a first elongated arm; the first securing member being configured to be inserted into the first elongated groove, the received portion of the first securing member being slidingly moveable to a selectable position in the first elongated groove; and a first attachment mechanism, the first attachment mechanism being configured to secure the securing member to the first elongated groove.
US11400853B2 Sleeper cabs for gooseneck trailers
Sleeper cabs for a gooseneck trailer. The gooseneck trailer includes a horizontal neck portion coupled to a cargo bed of a truck. The sleeper cabs include a base and an enclosure. The base is configured to securely mount to the horizontal neck portion of the gooseneck trailer. The enclosure defines a mobile dwelling supported on the base. In some examples, the sleeper cabs include a ladder to assist with climbing up to or descending from the enclosure.
US11400850B1 Stowable modular utility lift system
The subject invention pertains to stowable, modular lift conversion systems configured for aftermarket or OEM application to a truck, all-terrain vehicle (ATV), or utility task vehicle (UTV). Lift systems provided include removable and mounted systems with power provided by a battery, a winch, or linear motion device either on the lift or on the vehicle. Modular implements and lift attachments are provided.
US11400849B2 Portable conveyor system for use with a vehicle
A portable and articulating conveyor belt device for use with a vehicle having a power supply, wherein the vehicle's power supply powers the conveyor belt device. The conveyor belt device is removably attachable to a trailer hitch assembly on a vehicle, and enables a user to quickly and safely load articles onto/off of the vehicle via a conveyor belt. The conveyor belt device is preferably controlled via a remote control and controls the position of the device, as well as the direction and speed of the conveyor belt. The support frame of the conveyor belt device is comprised of a plurality of repositionable, interlocking and pivoting support frame members that enable the device to be arranged in a variety of configurations to suit user need and/or preference.
US11400847B2 Refrigerator, refrigerating or warming apparatus, and vacuum adiabatic body
A vacuum adiabatic body includes a first plate, a second plate, a sealing part that seals the first plate and the second plate to provide a space that has a predetermined temperature and is in a vacuum state, a support maintaining the space, a heat resistance unit reducing an amount of heat transferred between the first plate and the second plate, a port through which air in the third is discharged, and a heat exchange module coming into contact with an inner surface of a cavity provided by the first plate member and the second plate member so as to perform heat exchange.
US11400846B2 Foot rest assembly for a seat of a motorized vehicle
A foot rest assembly includes a foot rest member movable between a stowed position and a deployed position. The assembly further includes a leg having a first leg end coupled to the foot rest member and a second leg end, and an arm assembly including a flange and a track. The track includes a first track end and a second track end. A bearing assembly is coupled to the second leg end of the leg. In the deployed position, the bearing assembly and second leg end are located at the first end of the track. In the stowed position, the bearing assembly and second leg end are located at the second end of the track.
US11400840B2 System and method for seat vibration cancellation
A method for cancelling seat vibration includes receiving a first accelerometer measurement. The method also includes receiving a second accelerometer measurement. The method also includes determining a counter torque value based on the first accelerometer measurement and the second accelerometer measurement. The method also includes selectively controlling a motor using the counter torque value.
US11400835B2 Power slide
A power slide includes a left slide and a right slide, each including a top rail, a bottom rail, a lead screw and an electric motor. The top rail is arranged above the bottom rail and is slidably connected to the bottom rail, and a notch is formed in a middle portion of the top rail. The lead screw is arranged above the bottom rail in parallel and has two ends fixedly connected to the bottom rail. The electric motor includes a housing, a rotor shaft and a stator shaft. The housing is mounted in the notch, the stator shaft is fixedly connected into the housing, the rotor shaft penetrates into the stator shaft and is rotatably connected to the stator shaft, and an interior of the rotor shaft is threadedly connected to the lead screw.
US11400834B2 Adjusting interior configuration of a vehicle based on external environment data
A system and method are provided for controlling an interior configuration of a vehicle. The system may include an interior vehicle component, an actuator component configured to adjust a physical configuration of the interior vehicle component, an external communication component configured to collect driving environment data representing an external environment of the vehicle, and one or more processors configured to receive driving environment data and detect, by processing the driving environment data, an external driving condition. When the one or more processors detect the external driving condition, the one or more processors may cause the actuator component to adjust the interior vehicle component from a first physical configuration to a second physical configuration, or may cause the actuator component to restrict movement of the interior vehicle component to a predetermined range of physical configurations.
US11400833B2 Fuel cell vehicle and liquid state estimation method
A fuel cell vehicle is equipped with a fuel cell system including a gas liquid separation unit for separating gas and liquid and discharging the separated liquid. The fuel cell vehicle includes an acceleration sensor for detecting information regarding acceleration, and a control unit for estimating the discharge state of the liquid from the gas liquid separation unit based on the information regarding acceleration. Based on acceleration applied to the liquid in the gas liquid separation unit, the control unit can estimate whether the liquid is discharged from the gas liquid separation unit or the liquid is not discharged and remains as the remaining liquid in the gas liquid separation unit.
US11400832B2 Electrically powered vehicle
An electrically powered vehicle includes a target battery that is externally chargeable and externally power feedable, a sensor that detects a temperature of the target battery, and a controller that performs charging control, discharging control, and temperature increase control of the target battery. The temperature increase control is control for increasing a temperature of the target battery by selecting any of external electric power and battery power and generating heat with the selected electric power. The controller receives a leveling signal that requests for power leveling. When the temperature of the target battery is lower than a first temperature during external power feed requested by the leveling signal, the controller performs the temperature increase control by using battery power before the external power feed requested by the leveling signal.
US11400823B1 Dynamic scheduling of tasks and charging of an autonomous mobile device
A robot operates using electrical power. The robot is able to autonomously return to a dock to recharge its batteries. The robot may perform a variety of tasks that consume electrical power, such as performing video calls, presenting audio or video content, acting as a sentry, and so forth. Usage of the robot is analyzed to predict tasks that a user is likely to request. This information is used along with information about previously scheduled tasks and system tasks to create a list of tasks to be performed and when to perform those tasks. The tasks to be performed are calculated to maximize availability of the robot to the user while minimizing charge/discharge cycles, minimizing the extent of the charge/discharge, and minimizing the use of rapid charging. As a result, the lifespan of the batteries may be increased.
US11400821B2 Electric-vehicle charging apparatus
An apparatus for a power system. The apparatus includes multiple electrical power sources and an enclosure operatively connected to the power sources at multiple input terminals. Multiple loads operatively connect to the enclosure at multiple output terminals by multiple cables. The enclosure includes the input terminals and the output terminals and a controller unit. Multiple selection units operatively connect to the controller unit, multiple power converters are connected to multiple connection paths. The selection units connect to at least one of multiple switches connected in the connection paths. Multiple sensor units are operatively attached to the controller unit which is configured to sense multiple parameters in the connection paths. Responsive to the parameters sensed by the sensor units, the selection units select the connection paths between the electrical power sources and the loads.
US11400809B2 Method for operating a power take-off shaft of an agricultural tractor with an attachment hoist
A method for operating a power take-off shaft of an agricultural tractor with an attachment hoist includes providing a power take-off shaft spatially assigned to the attachment hoist, a hoist controller and a control unit. The method also includes detecting an operating state of the power take-off shaft via a first sensor and an upper operating position of the attachment hoist via a second sensor. The method further includes restricting the upper operating position to a first maximum value by the control unit if the first sensor detects that the power take-off shaft is not operating, and restricting the upper operating position to a second maximum value by the control unit if the first sensor detects that the power take-off shaft is operating, where the second maximum value is less than the first maximum value.
US11400805B2 Refueling control system for internal combustion engine
A refueling control system for an internal combustion engine includes a fuel tank; a vapor pipe; a step motor-driven shut-off valve; a fuel filler lid; and an electronic control unit configured to, when the fuel filler lid is to be opened, i) drive the shut-off valve such that the shut-off valve is opened, ii) close the fuel filler lid when an opening degree of the shut-off valve is less than a set opening degree, and iii) open the fuel filler lid when the opening degree of the shut-off valve is greater than or equal to the set opening degree. The electronic control unit sets the set opening degree such that the set opening degree when an opening speed of the shut-off valve is low is greater than the set opening degree when the opening speed of the shut-off valve is high.
US11400803B1 Vehicle driveline component
A vehicle driveline component includes a hollow motor shaft and a link shaft. The hollow motor shaft is supported for rotation about an axis including a plurality of grooves extending along an interior surface of the motor shaft. The link shaft cooperates with the interior surface of the motor shaft and the grooves to define a space between the link shaft and the motor shaft. The grooves are configured to force liquid lubricant to flow through the space in a longitudinal direction relative to the link shaft and the motor shaft when the motor shaft rotates. The link shaft includes a lubricant passage, a first connecting lubricant passage, and a second connecting lubricant passage. The lubricant passage extends along a longitudinal direction of the link shaft. The first and second connecting lubricant passages provide fluid communication between the longitudinal lubricant passage and the space.
US11400802B2 Cargo securing device, tonneau cover system, and method of use
A cargo securing device, a tonneau cover system comprising the cargo securing device, and a method of using the cargo securing device. The tonneau cover system includes a tonneau cover assembly having a tonneau cover and opposing frame rails supporting the tonneau cover on a cargo area of a vehicle. The cargo securing device includes a sleeve and an opening that provides access into the sleeve. The sleeve receives one or more panels of the tonneau cover so that the sleeve surrounds at least a portion of the one or more panels. The cargo securing device can be employed to secure cargo within the cargo area.
US11400799B2 Sliding laminated glazing unit with interior projection
An automotive glazing unit includes a glazing and a system for allowing the glazing to be moved translationally with respect to a door of the vehicle. The glazing is curved and laminated and includes an exterior and an interior glass sheet and a plastic sheet located between the exterior and interior glass sheets. Each sheet has a peripheral edge face. The interior glass sheet is a glass sheet that has undergone a chemical tempering operation and has a thickness included between 0.40 and 2.10 mm and the edge face of the interior glass sheet is located beyond the edge face of the plastic sheet and beyond the edge face of the exterior glass sheet over at least one portion of the length of the edge face of the interior glass sheet.
US11400798B2 Windshield quick attach and release system
An attach and release system for securing a windshield to a pillar includes an extrusion that is securable to the windshield adjacent the pillar. The extrusion has a connection tab and a seal tab. A bulb seal is connected to the seal tab, and a clamp includes a pillar section securable to the pillar and a connector section securable to the connection tab. The system and method facilitate windshield installation and removal and are suited for a utility task/terrain vehicle (UTV) as part of its rollover protection structure (ROPS).
US11400794B2 Flap-cushioning pressure relief assembly
A pressure relief assembly includes a housing defining an air passage chamber having at least one airflow opening. A flap is secured within the air passage chamber. The flap is configured to move into an open position to expose the airflow opening(s) to relieve air pressure. A cushion is secured to the housing underneath the flap. The cushion is configured to cushion motion of the flap. A first attachment securely couples the flap to the housing. A second attachment securely couples the cushion to the housing. The first attachment is separate and distinct from the second attachment.
US11400792B2 Interior temperature sensor for vehicle
The present disclosure relates to an interior temperature sensor for a vehicle. The sensor includes a sensor casing disposed to expose a sensing surface to a space that is the subject of temperature measurement, a substrate extending in a direction from an inside of the sensing surface toward an outside while at least a part of the substrate bisects an inside of the sensor casing into upper and lower sections, an upper temperature sensing element provided on an upper surface of the substrate at a position inside the sensor casing, a lower temperature sensing element provided on a lower surface of the substrate at a position inside the sensor casing, and a compensation temperature sensing element provided on the substrate to be placed outside the sensor casing. Furthermore, a microcomputer determines an interior temperature of the vehicle based on the measured values.
US11400789B2 Load dependent damper for a vehicle suspension system
A valve assembly for a vehicle suspension system includes a valve body, a first flow controller, a first plunger, a second flow controller, and a second plunger. The valve body defines a first inlet port, a first outlet port, a first chamber connected to the first inlet port and the first outlet port, a second chamber, a second inlet port, a second outlet port, a third chamber connected to the second inlet port and the second outlet port, and a fourth chamber. The first flow controller is positioned within the first chamber. The first plunger is positioned between the first chamber and the second chamber. The second flow controller is positioned within the third chamber. The second plunger is positioned between the third chamber and the fourth chamber.
US11400786B2 Vehicle having suspension with continuous damping control
A damping control system for a vehicle having a suspension located between a plurality of ground engaging members and a vehicle frame includes at least one adjustable shock absorber having an adjustable damping characteristic. The system also includes a controller coupled to each adjustable shock absorber adjust the damping characteristic of each adjustable shock absorber, and a user interface coupled to the controller and accessible to a driver of the vehicle. The user interface includes at least one user input to permit manual adjustment of the damping characteristic of the at least one adjustable shock absorber during operation of the vehicle. Vehicle sensors are also be coupled to the controller to adjust the damping characteristic of the at least one adjustable shock absorber based vehicle conditions determined by sensor output signals.
US11400784B2 Vehicle having suspension with continuous damping control
A damping control system for a vehicle having a suspension located between a plurality of ground engaging members and a vehicle frame includes at least one adjustable shock absorber having an adjustable damping characteristic. The system also includes a controller coupled to each adjustable shock absorber to adjust the damping characteristic of each adjustable shock absorber, and a user interface coupled to the controller and accessible to a driver of the vehicle. The user interface includes at least one user input to permit manual adjustment of the damping characteristic of the at least one adjustable shock absorber during operation of the vehicle. Vehicle sensors are also be coupled to the controller to adjust the damping characteristic of the at least one adjustable shock absorber based vehicle conditions determined by sensor output signals.
US11400782B2 Axle assembly and method of manufacture i'hereof
Described herein is an axle assembly and method of fabrication thereof. The axle assembly includes an axle having a first geometric shape housed within an axle housing having a second geometric shape. A shock absorber is located between the axle and the axle housing. The shock absorber supports the axle within the axle housing and comprises a first material and comprises a multi-sided configuration. The first geometric shape and the second geometric shape comprising polygons.
US11400776B2 Hydraulic lift mechanism and method of use
A hitch mechanism adapted to be attached to a vehicle and support a device includes a hitch receiver adapted to attach to the vehicle and a pair of pull arms. A first end of each pull arm is attached to the hitch receiver and a second end of each pull arm is configured to attach to the device. Each pull arm has an adjustable length and being pivotal horizontally and vertically. The hitch assembly allows a device such as a material spreader to be attached to a vehicle so that the device can be operated in its intended way.
US11400773B2 Tire pressure sensor capable of replacing a valve assembly according to different use requirements
The present invention relates to the field of tire pressure detection technologies, and discloses a tire pressure sensor, including: a sensor assembly provided with a through hole; a valve assembly including a valve rod, a valve cover mounted to one end of the valve rod, a rod sleeve sleeved between two ends of the valve rod and a fastener connected to the other end of the valve rod through threads, one of the fastener and the valve rod passing through the through hole, and the fastener and the valve rod clamping the sensor assembly, where there are at least two sets of valve assemblies, the at least two sets of the valve assemblies being alternatively connected to the sensor assembly, a rod sleeve of one of the at least two sets of the valve assemblies being made of a metal material, and a rod sleeve of the other of the at least two sets of the valve assemblies being made of a rubber material. The at least two sets of valve assemblies with different specifications may alternately be connected to the sensor assembly, and a user may mount, according to requirements, a valve assembly that meets the requirements.
US11400769B2 Tire
A tire includes tire frame members including bead cores, a bead filler, an inner liner, side-wall rubber and cushion rubber; and an electronic unit provided at an interface of tire frame members, the tire further including: a carcass ply which extends from one bead core to another bead core and includes a rubber-coated reinforcement cord, a belt disposed on the outer side in the tire-radial direction of the carcass ply, in which the cushion rubber is disposed at an end of the carcass ply or at an end of the belt, in which the side-wall rubber is disposed on an outer side in a tire-width direction of the cushion rubber, and in which the electronic unit is disposed between the cushion rubber, and the bead filler or the side-wall rubber.
US11400766B2 Cable bead and tire
Disclosed are a cable bead and a tire. The cable bead includes a core wire located at the middle position of the bead and at least one layer of outer winding wires wound around the core wire, each layer of outer winding wires being evenly wounded along the circumferential direction of the core wire, where the cross section of the outer winding wires is a flat surface having a major axis and a minor axis; the major axis is perpendicular to the radial direction of the cross section of the bead, and the minor axis is parallel to the radial direction of the cross section of the bead; the outer winding wires are in surface contact with the core wire; and when there are at least two layers of outer winding wires, a line contact is formed between the layers of outer winding wires.
US11400759B2 Pneumatic tire
A pneumatic tire includes: a carcass; at least one layer of a belt; and a tread, the belt including an endless belt layer having provided therein treats, each of the treats being formed by covering a cord with rubber and extending in zigzag fashion in the tire circumferential direction, in which in the endless belt layer, a front surface a and a rear surface of each of the treats are reversed at both tire widthwise ends, and on at least one tire widthwise end of the treats, a treat reversal position is, at least partially in the tire circumferential direction, displaced in the tire width direction from another treat reversal position adjacent in tire circumferential direction.
US11400756B2 Tire for heavy goods vehicle
The tire has a radial carcass reinforcement intended to equip vehicles carrying heavy loads and running at sustained speed. The tire comprises a crown reinforcement, itself capped radially with a tread joined to two beads via two sidewalls. The tread comprises at least two radially superposed layers of polymeric compound, a radially outer first layer that comes into contact with the ground and a radially inner second layer. The second layer has a composition based on at least a diene elastomer, a reinforcing filler comprising predominantly a filler covered at least partially by silica, an agent for coupling the filler with the elastomer and a crosslinking system. The dispersion of the filler in the elastomeric matrix has a Z value greater than or equal to 70.
US11400752B2 Composite wheel assembly and method of construction thereof
A composite wheel assembly and method of construction thereof is provided. The composite wheel assembly includes a lightweight annular aluminum barrel having an inner surface and an outer surface configured to support a tire thereon. A lightweight metal central hub assembly is fixed to the barrel. The metal central hub assembly includes a central hub portion and plurality of support spokes extending outwardly from the central hub portion to free ends, wherein the free ends are fixed to the inner surface of the aluminum barrel. A wheel cladding contrasting in at least one of material type, color, texture and surface finish to an outwardly facing surface the central hub assembly is fixed to the outwardly facing surface of the central hub assembly.
US11400750B2 Adjustable brush holding assembly
A holder assembly for holding a painting tool within a paint container is provided. The holder assembly includes an inner tube including an attachment mechanism for receiving the painting tool, an outer tube that receives the inner tube, wherein the outer tube includes a securement means for attaching to the paint container, and a tightener to secure a position of the inner tube within the outer tube.
US11400742B2 Thermal transfer image-receiving sheet
A thermal transfer image-receiving sheet has a primer layer and a receiving layer. The primer layer contains binder resin and metal pigment. When a value obtained by dividing the mass of the metal pigment by the mass of the binder resin is A and the thickness of the primer layer is B, A is 0.5 to 3.5, and A/B is 0.15 to 6. When light is made incident on the surface on the receiving layer side at an incident angle of 45°, ΔL* between L* at a light-receiving angle obtained by tilting specular reflection light, generated when light is made incident on the surface on the receiving layer side at an incident angle of 45°, toward the incident light side by 15° and L* at a light-receiving angle obtained by tilting the specular reflection light toward the incident light side by 110° is 110 or more.
US11400741B2 Group IV metal chelates and their use in radiation curable ink and coating compositions
Described herein are inks and coating compositions curable by exposure to UV energy sources including UV-LED energy sources, which include a polymerizable component selected from an ethylenically unsaturated materials, a photoinitiator component that is one or more photoinitiators, one of which is an acyl phosphine oxide photoinitiator; and a Group IV metal chelating agent. Improved cured is realized for the described inks and coating compositions.
US11400738B2 Image processing apparatus
An image processing apparatus includes an apparatus body, a feeding cassette, a pin member, a lever, an elastic member, and a guide mechanism. The feeding cassette is insertable into and ejectable from the apparatus body in one direction and includes an insertion position for insertion into the apparatus body and an ejection position for ejection from the apparatus body. The pin member is connected to the feeding cassette. The lever is rotatable around an axis in a first direction, and includes a pin engagement portion engaging with the pin member at a tip end in the axial direction. The elastic member includes a tip end connected between the rotation axis of the lever and the pin engagement portion of the lever, and adds a force for rotation in an insertion direction. The guide mechanism shortens a distance between the pin member and the rotation axis of the lever.
US11400736B2 Image forming apparatus
The image forming apparatus includes a moving unit, a movable connector, a fixed connector, a wire, a fixed wire guide and a movable wire guide. The moving unit is supported by a casing in an upwardly and downwardly moving manner. The movable connector is provided in the moving unit. The fixed connector is provided in the casing. Both ends of the wire are connected to the movable connector and the fixed connector. The wire has a length longer than a distance between the movable connector and the fixed connector at lifting of the moving unit. The fixed wire guide is supported on the bottom plate of the moving unit. The movable wire guide is supported on the bottom plate of the casing. At least one of the movable wire guide and the fixed wire guide is supported rotatably.
US11400734B2 Image recording apparatus
There is provided image recording apparatus including: memory and controller. The controller is configured to store, in the memory, first identification information for identifying recorded image and minimum margin value being a minimum value of partial image margins of recorded partial images. The controller is configured to obtain second identification information for identifying image-to-be-recorded. In a case that second identification information is same as first identification information stored, the controller is configured to determine whether the minimum margin value is smaller than threshold or not, and then: in a case that the minimum margin value is smaller than threshold, the controller is configured to derive an edge position of the sheet, and then execute ejection based on the derived edge position; and in a case that the minimum margin value in not smaller than threshold, the controller is configured to execute the ejection without deriving the edge position.
US11400729B2 Ink jet recording method, ink set, and ink jet recording apparatus
According to the present disclosure, an ink jet recording method includes depositing a resin liquid onto a non-absorption or low-absorption recording media and depositing an aqueous ink composition onto the recording medium by using an ink jet method, the recording medium including the resin liquid deposited on the recording medium, the aqueous ink composition having a total content of organic solvents of less than or equal to 12.0 mass % relative to the total mass of the aqueous ink composition.
US11400728B2 Printing apparatus and printing method
The area of the openings Ow that discharges the white ink is larger than the area of the openings Ot that discharges the color inks. Since the openings Ow are secured to be large in this way, more white ink can be discharged to one pixel while the number of ink droplets discharged by the multi-drop method is suppressed or without depending on the multi-drop method. As a result, a generation amount of an ink mist can be suppressed while the discharge amount of the white ink is secured.
US11400725B2 Liquid ejection apparatus
A liquid ejection apparatus that prevents a user's hand from becoming dirty when attaching and detaching a liquid holding container, the liquid ejection apparatus includes a space portion that is open on a side surface of a housing, a liquid holding container that is detachably mounted to the space portion and includes an introduction port for introducing liquid to an inside thereof, on an upper surface, and a discharge portion that is provided at a position facing the introduction port inside the space portion in a state in which the liquid holding container mounted and includes a discharge port for discharging the liquid to the inside of the liquid holding container, in which the discharge portion is configured such that at least the discharge port is movable.
US11400724B2 Ink receptacle
An ink receptacle includes an inner bag filled with an aqueous ink jet ink and a pliable sheath containing the inner bag. The inner bag contains a gas phase in a volume fraction of 0.001 or more relative to the capacity of the inner bag. The aqueous ink jet ink contains a dispersed component, an acetylene glycol surfactant having an HLB of 11 or more, and an acetylene glycol surfactant having an HLB of 9 or less.
US11400723B2 Method of engaging supply module with printhead
A method of engaging a supply module with a printhead includes the steps of: moving an actuator handle in a first motion along a first axis, thereby linearly sliding the supply module along the first axis towards the printhead and engaging ink couplings of the supply module with complementary ink ports of the printhead; and moving the actuator handle in a separate second motion along a second axis perpendicular to the first axis, thereby moving a PCB of the supply module towards the printhead and engaging PCB contacts with complementary printhead contacts.
US11400719B2 Liquid ejecting apparatus and maintenance method for liquid ejecting apparatus
A liquid ejecting apparatus includes: a liquid ejecting portion configured to eject a first liquid from a nozzle; a liquid receiving portion configured to receive the first liquid discharged from the nozzle for a purpose of maintenance of the liquid ejecting portion in a state that a second liquid is stored therein; and a discharge portion configured to discharge a liquid stored in the liquid receiving portion. The liquid receiving portion includes: a liquid storing portion that stores the second liquid; a maintenance portion that maintains a liquid surface of the liquid stored in the liquid storing portion at an upper limit position above a discharge port at which the discharge portion discharges the liquid from the liquid storing portion; and a lip portion configured to contact the liquid ejecting portion. The liquid receiving portion is configured to cap a space in which the nozzle opens with the lip portion.
US11400714B2 Method for magnetohydrodynamic (MHD) printhead/nozzle reuse
A method for operating a printer can include draining a print material from a printer, placing a sacrificial metal into the printer, ejecting the sacrificial metal from a nozzle of the printer, and cooling to printer to a temperature that is below a melting point of the print material and the sacrificial metal. The print material can be or include aluminum and the sacrificial metal can be or include tin. The print material can be drained from the printer when the print material is in molten form, for example, from about 600° C. to about 2000° C. The sacrificial metal can be ejected from the nozzle at a temperature above the melting point of the sacrificial metal but below the melting point of the print material, for example, below about 300° C. The method can reduce or eliminate cracking of various printer structures such as the nozzle during a shutdown or cooling of the printer.
US11400708B2 Liquid ejecting apparatus
the ejection amount per ejection from the nozzle when the distance between the nozzle and the recording medium is the first distance is equal to the ejection amount per ejection from the nozzle when the distance between the nozzle and the recording medium is the second distance.
US11400699B2 Layer transferring device including heat roller provided in main casing and movable relative to pressure roller provided at cover
A layer transferring device includes: a main casing having an opening and accommodating a heat roller, a motor, and a first transmission gear therein; a film cartridge; and a cover at which a pressure roller and a second transmission gear is provided and movable about a pivot axis to open and close the opening. The heat roller is movable toward and away from the pressure roller when the cover is closed. When the film cartridge is attached to the main casing and the cover is closed, the multilayer film contacts and passes through between the pressure roller and the heat roller. When the cover is closed, the first transmission gear for receiving a driving force from the motor and the second transmission gear for transmitting a driving force to the pressure roller are positioned between the pivot axis and the heat roller and in meshing engagement with each other.
US11400697B2 Window manufacturing system and window manufacturing method using the same
A window manufacturing system includes a first processing unit in which a process of providing a dummy substrate on a stage is performed, a second processing unit in which a process of providing a dummy adhesive layer on the dummy substrate is performed, a third processing unit in which a process of providing a window layer on the dummy adhesive layer is performed, and a fourth processing unit in which a process of providing a protective cover on the window layer is performed. The fourth processing unit includes a pressurization unit which presses the protective cover to the window layer.
US11400696B2 Bonding devices and bonding methods for irregular-shaped curved cover plates and flexible screens
A bonding device and a bonding method for an irregular-shaped curved cover plate and a flexible screen are disclosed. The bonding device includes a bonding body pressing the flexible screen, the bonding body includes: an adsorption component configured to adsorb the flexible screen, the adsorption component includes a plurality of sub-adsorption components arranged apart from each other; and an expansion component having a variable size, the expansion component includes a plurality of sub-expansion components arranged apart from each other. The adsorption component and the expansion component are cooperatively provided with a pressing surface having a shape adapted to a shape of an inner surface of the irregular-shaped curved cover plate.
US11400692B2 Odor-managed ostomy film
The present disclosure provides a film. In an embodiment, a multilayer film is provided and includes (A) a seal layer, (B) a barrier layer, and (C) an odor control layer. The odor control layer includes an odor control composition containing (A) from 85 wt % to 99.5 wt % of an olefin-based polymer and (B) from 15 wt % to 0.5 wt % of an odor suppressant. The odor suppressant includes a blend of: (i) an ionomer, (ii) particles of zinc oxide, and (iii) particles of copper oxide. The composition has a methyl mercaptan odor suppression value of greater than 45% as measured in accordance with ASTM D5504-12.
US11400691B2 Methods of forming shaped glass articles from glass sheets
A method of forming a 3D glass article from a glass sheet includes locating the glass sheet on a mold assembly including a mold surface with a 3D surface profile corresponding to that of the 3D glass article. The glass sheet is heated to a forming temperature. The forming temperature is greater than a temperature of the mold surface. The heated glass sheet is forced onto the mold surface by applying a pressurized gas to a first surface of the glass sheet opposite the mold surface to conform the glass sheet to the mold surface with the glass sheet at the forming temperature that is greater than the temperature of the mold surface.
US11400690B2 High performance press-hardened steel assembly
A press-hardened steel assembly after hot stamping/hot forming including a core layer having a tensile strength of ≥about 1,800 megapascals to ≤about 2,200 megapascals and ≥about 90 volume % martensite, the core layer having a first thickness ≥about 40% to ≤about 96% of the thickness of the press-hardened steel assembly; and a first surface layer along a first surface of the core, the first surface layer having a tensile strength of ≥about 800 megapascals to ≤about 1,200 megapascals and ≥about 90 volume % martensite and bainite. The press-hardened steel assembly has a tensile strength of ≥about 1,600 megapascals to ≤about 2,000 megapascals and a VDA 238-100 bending angle of ≥about 50° to ≤about 80°.
US11400689B2 Tape-like dry fibrous reinforcement
A tape-like dry fibrous reinforcement, the ‘Gapped UD reinforcement tape’, providing channels or flow-paths created by inclusion of a layer of separated fiber tows held by at least one adhesive layer. Hereby, quicker wetting of fibers with matrix is obtained, whereby improved composite materials can be economically produced. A method and apparatus for producing the Gapped UD tapes are also disclosed.
US11400688B1 Thermal protection barrier
A thermal protection barrier including a base layer having a high melting temperature granular media having free standing granules disposed within the base layer and a distributor grid layer having a plurality of spaced-apart distributors composed of a high melting temperature material disposed adjacent to the base layer. The spaced-apart distributors are dimensioned and configured to provide load bearing support to the thermal protection barrier prior to a breach of the thermal protection barrier and to divide and disperse a superheated flowing mass to the free standing granules of the base layer upon occurrence of a breach. In certain embodiments, the thermal protection barrier is positioned adjacent to a nuclear system such that, upon occurrence of a loss of containment accident, the distributor grid layer is positioned and configured to divide and disperse a superheated flowing nuclear mass to the free standing granules.
US11400685B2 Gradually recruited fiber reinforced polymer (FRP) composite
A 3D printed fiber reinforced polymer composite having a nonlinear stress-strain profile created by a central layer and a plurality of recruited successive layers.
US11400680B2 Converting machine
A system that converts sheet material into packaging templates includes a converting assembly that performs conversion functions, such as cutting, creasing, and scoring, on the sheet material as the sheet material moves through the converting machine in a first direction. The converting assembly may be mounted on a frame such that the converting assembly is elevated above a support surface. One or more longhead converting tools performs conversion functions on the sheet material in a first direction and a crosshead converting tool performs conversion functions on the sheet material in a second direction in order to create packaging templates.
US11400675B2 Mold and method for forming a pressurized fluid chamber
A fluid chamber for a shoe may be formed using pressure channels in a forming mold, eliminating the need to insert a nozzle or needles into the chamber for inflation. A fluid chamber so formed may have a smaller seal area than a chamber formed using an inflation needle, making the chamber more visually pleasing. Apparatus and methods for forming a fluid chamber in this fashion are also disclosed.
US11400674B2 Sheet molding production method
Disclosed is a manufacturing method of a sheet molded article, including the steps of: thermoforming a molding sheet with a first mold, thereby molding a molded article including a body portion provided with a shape transferred from the first mold, and a peripheral edge portion surrounding the body portion; and removing the molded article from the first mold, and inverting the body portion front-to-back.
US11400667B2 Tire maintenance means
A tire maintenance means (1) is provided, which includes a monitoring module (2) for monitoring the status of a tire; an inflating module (4) for inflating or deflating the tire; a repairing module (5) for filling a sealant to the tire; a control module (3) for maintaining the tire based on a signal from the monitoring module (2). A method of maintaining a tire is also provided.
US11400666B2 Laser projection device and method for manufacturing composite material parts by drape-molding
A laser projection method and device for drape-molding a part on a mold includes encoders to determine the theoretical position of calibration patterns according to a displacement of the mold such that a laser projector is automatically recalibrated when the mold is repositioned during the drape-molding operation.
US11400660B2 Pressure sensitive flow distribution medium for VARTM
A method for manufacturing a fibre reinforced composite by means of a vacuum assisted resin transfer moulding, comprising the steps of placing a fibre material in a mould, placing a flow distribution medium onto the fibre material, and covering the fibre material (1) and the flow distribution medium with a vacuum foil for forming a closed mould cavity between the mould and the vacuum foil is described. It is characterised in using a flow distribution medium with a thickness depending on a pressure gradient over the vacuum foil.
US11400650B2 Methods and systems for stereolithography three-dimensional printing
The present disclosure provides method and systems for printing a three-dimensional (3D) object. A method for 3D printing may comprise providing a mixture comprising (i) a polymeric precursor, (ii) a photoinitiator configured to initiate formation of a polymeric material from the polymeric precursor, and (iii) a photoinhibitor configured to inhibit the formation of the polymeric precursor. The method may comprise exposing the mixture to (i) a first light to cause the photoinitiator to initiate formation of the polymeric material, thereby to print the 3D object, and (ii) a second light to cause the photoinhibitor to inhibit the formation of the polymeric material. During printing of the 3D object, a ratio of (i) an energy of the second light sufficient to initiate formation of the polymeric material relative to (ii) an energy of the first light sufficient to initiate formation of the polymeric material may be greater than 1.
US11400646B2 Additive production process using a mixed thermoplastic construction material
The present invention relates to a method for producing an object, comprising the step of producing the object according to an additive production process from a construction material, wherein the construction material comprises a mixture of a plurality of powdery thermoplastic materials which are different from one another due to at least one mechanical property and at least one thermoplastic material is a thermoplastic polyurethane material. The invention also relates to an object obtained according to said method.
US11400642B2 3D printing heat resistant support material
A filament for use in forming a support structure in fused filament fabrication, the filament comprising an amorphous, thermoplastic resin further comprising Bisphenol Isophorone carbonate units and Bisphenol A carbonate units, wherein the Bisphenol Isophorone carbonate units are 30 to 50 mole percent of the total of Bisphenol A carbonate units and Bisphenol Isophorone carbonate units in the resin, and wherein the resin has a glass transition temperature from 165° C. to 200° C. The composition used to form the support filament exhibits a desirable combination of filament formability, printability, lack of significant oozing from the printer nozzle, and good ease of mechanical separation from the build material at room temperature after printing.
US11400641B2 Apparatus and method for forming a three-dimensional object
An apparatus and a method for forming a dimensionally stable, three-dimensional object (12) by consecutively or continuously applying and hardening a shapeable printing material (89).
US11400638B2 Method for manufacturing liquid-filled container
A liquid container manufacturing method includes: a liquid blow molding step of molding a preform into a liquid container having a shape conforming to an inner surface of a blow-molding mold, by supplying a pressurized liquid to an interior of the preform through a supply path in a state where a blow nozzle is engaged to a mouth of the preform; and a headspace forming step of forming a headspace in the liquid container, by discharging the liquid from an interior of the liquid container through a discharge port in a discharge rod extending to the interior of the liquid container through the blow nozzle, by introducing a pressurized gas to the interior of the liquid container through a gas inflow path in a state where the supply path is closed.
US11400636B2 Base for an accessory and tank accessory, method for producing a tank
A base made from plastic material for a motor vehicle tank accessory, including protrusions to be welded to a preform during production of the tank by blowing the preform, wherein: the base includes a solid surface recessed from the protrusions, the solid surface including a part without protrusions and a part taken up by the protrusions, the area of the part of the solid surface without protrusions is at least equal to one times the area of the solid surface taken up by the protrusions, the height of the protrusions relative to the solid surface is between 0.6 mm and 0.8 mm.
US11400632B2 Extruder screw with conveying portions and barrier portions and extrusion methods using the extruder screw and a plurality of barrel blocks
An extruder includes a screw for extruder provided with a screw element for kneading a raw material, and a barrel including a cylinder portion in which the screw is inserted so as to be rotatable. A plurality of screw elements identical with the screw element are provided in a longitudinal direction of the screw under a certain rule. The barrel is integrated by combining a plurality of barrel blocks blocked. Each of the plurality of barrel blocks is configured in accordance with a length of the screw element provided in the longitudinal direction of the screw.
US11400630B2 Method for increasing the injection speed of a plastic injection device
A method for increasing the injection speed of a melted plastic injection device for injecting said melted plastic into a molding cavity (51), said injection device comprising a first cylinder (1) provided with a tubular casing (2) defining a first inner diameter d1, and a first piston (3) slidable inside said tubular casing (2), adapted to be loaded with melted plastic and to inject said melted plastic toward the molding cavity (51); a second cylinder (21) constrained to the first cylinder (1) and provided with a second piston (23) which rod (24) is connected to the first piston (3) and is adapted to actuate said first cylinder (1) during an injection operation; the method comprising the steps of: —releasing second cylinder (21) and first cylinder (1) by extracting the first piston (3) from the tubular casing (2); —coaxially inserting a tubular body (12), defining a second inner diameter d3 which is smaller than the first inner diameter d1, into the tubular casing (2); —disconnecting the first piston (3) from the rod (24); —connecting a third piston (13) to the rod (24), said third piston (13) being sized to slide inside said tubular body (12); —constraining second cylinder (21) and first cylinder (1) by inserting the third piston (13) into the tubular casing (2).
US11400629B2 Injection molding die
An injection molding die includes a fixed die and a movable die that move in a die opening/closing direction relatively to each other. A cavity that is formed between the fixed die and the movable die in a die clamping state includes a lateral cavity portion that extends along the die opening/closing direction and a first orthogonal direction. The injection molding die includes a demolding core and a following core that define an end portion of the lateral cavity portion across the fixed die and the movable die in a second orthogonal direction. The demolding core and the following core are configured to be movable in the second orthogonal direction while defining the end portion of the lateral cavity portion across the fixed die and the movable die in the die clamping state, and to be engaged with the fixed die with substantially no play in the second orthogonal direction.
US11400624B2 Constant cross section mandrel for CMC components
A mandrel for a molding process that includes a first portion that has a first portion outer surface, a first portion inner surface, a first portion first end, and a first portion second end. A thickness of the first portion first end is greater than the first portion second end. A second portion has a second portion outer surface, a second portion inner surface, a second portion first end, and a second portion second end. A thickness of the second portion first end is smaller than the second portion second end. The first portion inner surface engages the second portion inner surface to form a mandrel that has a constant cross-section.
US11400623B2 Compression-molding system and method of controlling the same
A compression-molding system in which upon a start of a molding machine being stopped, a powdery-material feeding device preliminarily supplies a filling device with a predetermined amount of a powdery material while stopping a relative displacement of the filling device and a compression by an upper punch and a lower punch, and the molding machine is subsequently started to cause the relative displacement of the filling device and the compression by the upper punch and the lower punch.
US11400622B2 Method for manufacturing recyclable inorganic paper
A method is provided for manufacturing recyclable inorganic paper, which has a composition comprising 60-85 wt % mixture of natural inorganic mineral powders, inorganic glass powders, and sand powders, 5-40 wt % bonding agent of polypropylene (PP), and 1-5 wt % assisting agents, through the following steps: feeding and mixing of the constituents of the composition; stirring and mixing the composition; pressing to cause bi-directional extension of the composition so as to form a sheet; subjecting the sheet to operation of a high density squeezing machine for further mixing and pressing the sheet; reversely turning and shaping the sheet for further extension of the sheet; and continuous compression and extension of the sheet to induce further bi-directional extension of the sheet in both lateral and longitudinal direction and to control thickness of the sheet.
US11400614B2 Cutting machine with overview camera
Disclosed is a cutting machine for cutting a flat surface having a graphical design with optical registration features. The cutting machine includes a working surface for receiving at least one object, a first camera unit arranged so that the field of vision encompasses the whole working surface, a working group above the working surface, and at least one cutting device for cutting the at least one object. A computing unit with a circuit and program code for controlling the cutting machine includes a storage unit, a circuit and program code for evaluating images of the first camera unit to identify registration features of the at least one object in an image of the first camera unit, and being designed to define a cutting path for the cutting device according to at least one stored instruction and based on positions of the registration features in the image.
US11400612B2 Rotary cutter with interchangeable blade
The invention relates to a rotary cutter (10) with an exchangeable blade (33), which enables the blade (33) to be replaced easily with little risk of injury and can be used in a variety of ways. The rotary cutter (10) comprises a handle (20) and a blade holder (30) which is detachably connected to the handle (20). A solid casing of the blade holder (30) takes at least half of the blade (33) within it (FIG. 1).
US11400610B2 Skin adapter
A skin adapter designed to attach to a head unit of a razor, the skin adapter including an outer member, the outer member having a leading portion with a leading side, a trailing portion with a trailing side, and an aperture arranged between the leading portion and the trailing portion, the leading portion and trailing portion being positioned on an outermost surface of the outer member, the aperture being inaccessible from the leading and trailing side, and one or more ribbons positioned within the aperture of the outer member, the ribbons extending between the leading portion and trailing portion of the outer member.
US11400606B2 Articulated robot and method of estimating decrease state of gas in gas spring
An articulated robot has an arm, a drive motor for driving and positioning the arm, a gas spring for supporting a load acting on the arm to reduce a load of the drive motor and a control unit for controlling the drive motor. The control unit has a function of estimating a decrease state of a gas sealed inside the gas spring based on an actual current value of the drive motor obtained at a stop position at which the drive motor is operated and stopped in an energized state. The decrease state of the gas sealed inside the gas spring is estimated based on the current value of a servo motor without causing decline in operation rate of the robot.
US11400605B2 Rotatable cushioning pick-and-place device
A rotatable cushioning pick-and-place device primarily comprises a motor, a body, a cushioning module and a pick-and-place module. The cushioning module is disposed in a first chamber of the body and comprises a rotary bearing which is connected to a drive shaft of the motor, and coupled to a driven shaft sleeve through a rotary follower. The rotary follower is driven by the rotary bearing to drive the driven shaft sleeve to rotate, thereby allowing the rotary bearing to displace relative to the driven shaft sleeve axially. The cushioning spring is arranged between the rotary bearing and the driven shaft sleeve. A first sealing ring and a second sealing ring of the pick-and-place module are fixed on the body to cooperatively and air-tightly seal the second chamber.
US11400595B2 Robotic platform with area cleaning mode
A method and system for a robotic device comprising a propulsion mechanism to move the robotic device, a sensor, a user interface for entering service area dimension information to establish a service area proximate the robotic device, and a processing facility comprising a processor and a memory, the processing facility configured to store a set of instructions that, when executed, cause the robotic device to receive service area dimension information for the service area through the user interface, wherein the service area is determined by the service area dimension information entered into the user interface, and utilize the propulsion mechanism to move the robotic device through the service area and to perform a service task in the service area.
US11400590B2 Optimal control of coupled admittance controllers
A coupling device (16, 116, 216, 316) configured optimally to communicate between a first and a second admittance controller and actuator assembly, the first and the second admittance control and actuator assembly respectively having a first and a second admittance controller (12a, 12b) configured to drive a respective first and a second actuator and each of the first and the second actuator being respectively connected to a first body having a first mass and a second body having a second mass, wherein the coupling device (16, 116, 216, 316) comprises: an input port having a first input for receiving a first input force signal (f1) from the first admittance controller and actuator assembly (12a) and a second input for receiving a second input force signal (f2) from the second admittance controller and actuator assembly (12b), and a processor adapted to derive a first output force signal for output to the first admittance controller and actuator assembly based on a Lagrange multiplier dependent on a comparison of the first input force signal and the second input force signal.
US11400585B2 Actuator
An actuator (1) is described having a first part (4), a second part (2), and a body portion (3) between the first and second parts, wherein the body portion includes at least one chamber (14) configured to be pressurised and the body portion has a longitudinal axis; and a plurality of cables (6,7,8,9), wherein each of the plurality of cables is arranged in a respective at least partial spiral with respect to the longitudinal axis of the body portion (3); and wherein the plurality of cables are arranged such that the application of a selected force to at least one of the cables causes a desired movement of the first part relative to the second part.
US11400579B1 Dismantlable portable sawhorse
A dismantlable portable sawhorse utilizes a bracket plate having a plank aperture and a support aperture that have lengths that are substantially orthogonal to each other and intersect to form a continuous aperture having an intersection space. The plank and support apertures are configured to receive various arrangements of plank lumber and support lumber, respectively. The bracket plate also has a front and back leg cup configured to receive leg lumber therein to lift the bracket plates up from the ground. The sawhorse is formed with two bracket plates configured with at least one of support and plank lumber configured in the respective apertures and extending between the two bracket plates and with leg lumber configured in each of the front and back leg cups of each bracket plate. The bracket plates may lean inward toward each other at a stand angle.
US11400576B1 Earth breaking implement attachment
An earth breaking implement attachment includes a hydraulic pole ram capable of having a plurality of attachments secured to a foot. The attachment is presented in either a first embodiment or a second embodiment. The first attachment is shaped like a shark tooth. The second embodiment has a similar appearance of a screwdriver head.
US11400575B2 Pneumatic tool
A pneumatic tool includes a drive mechanism configured to be actuated by a pneumatic pressure of compressed air, a body housing having the drive mechanism embedded therein, a grip housing connected to the body housing, and an electromagnetic valve configured to control supply of the compressed air to the drive mechanism, wherein the electromagnetic valve is arranged on an opposite side to the body housing, as seen in an extension direction of the grip housing.
US11400573B2 Pneumatic tool
A pneumatic tool is provided comprising: a motor; a drive mechanism connected to the motor; a cylinder; the drive mechanism comprising a drive bar connected to a piston, the drive bar adapted to drive the piston in a linear direction; the cylinder filled with high pressure gas; wherein the piston is housed in the cylinder and adapted to reciprocate within the cylinder; the piston is connected to a striking member adapted to strike a workpiece; wherein the drive mechanism further comprises a plurality of latching members adapted to be in contact with and lock the drive bar. The latching structure provided by the present invention has a smaller sliding distance and is safer than conventional drive bar latching structures.
US11400571B2 Tongue break-off tool and tongue break-off method
A tongue break-off tool includes a hook member configured to have a hook hooked onto a tongue of an insert with a tongue that is inserted into a tap hole, a moving member configured to move the hook member in a diagonal direction diagonally intersecting an extending direction of the tap hole from a far side to a near side of the tap hole to break off the tongue from the insert with a tongue, and a holding member configured to hold the tongue broken off from the insert with a tongue.
US11400559B2 Polishing pad, process for preparing the same, and process for preparing a semiconductor device using the same
The polishing pad according to an embodiment adjusts the content of elements present in the polishing layer, thereby controlling the bonding strength between the polishing pad and the polishing particles and enhancing the bonding strength between the polishing particles and the semiconductor substrate (or wafer), resulting in an increase in the polishing rate. It is possible to enhance not only the mechanical properties of the polishing pad such as hardness, tensile strength, elongation, and modulus, but also the polishing rate for both a tungsten layer or an oxide layer. Accordingly, it is possible to efficiently fabricate a semiconductor device of excellent quality using the polishing pad.
US11400557B2 Floor grinding machine and method of operating floor grinding machine
This document provides a method of operating a floor grinding machine 100. The method comprises providing a grinding machine 100 comprising a frame 101, a motor 102 and at least one grinding element 1, causing the motor to drive the grinding element so as to rotate at a rotational speed, while in contact with a floor surface to grind, polish or mill the floor surface, determining an actual value of a motor operating parameter, determining a nominal value of the motor operating parameter, comparing the actual value of the motor operating parameter with the nominal value of the motor operating parameter, if a difference between the actual value of the motor operating parameter and the nominal value of the motor operating parameter exceeds a predetermined difference threshold, determining at least one grinding parameter to be adjusted, and causing the at least one grinding parameter to be adjusted.
US11400556B2 Abnormality detection apparatus for working tools
An abnormality detection apparatus for working tools configured to be used in a machining process performed by a machine tool, the abnormality detection apparatus includes a storage portion which previously stores correlations between features of a plurality of operating portions relation to the machining process performed by the machine tool, and a tool condition of each of a plurality of working tool types, and a tool condition determining portion which determines the tool condition of the working tools based on the correlations.
US11400548B2 Methods and laser welding devices for deep welding a workpiece
The disclosure relates to methods and systems for deep welding a workpiece, a surface of the workpiece being irradiated by a first laser beam and a second laser beam. In a workpiece surface plane (OE) a first beam width B1 of the first laser beam is larger than a second beam width B2 of the second laser beam and in at least the workpiece surface plane (OE) the second laser beam lies inside the first laser beam. The intensity of the first laser beam alone is sufficient to produce a keyhole in the workpiece. The keyhole produced in the workpiece has a width KB in the workpiece surface plane (OE), KB substantially equaling B1, and B2≤0.75*KB. The methods and systems provide good seam quality, high penetration depth, and high welding speed.
US11400546B2 Welding process for a battery module
The present disclosure relates generally to a welding process for a battery module. In an embodiment, a system for welding two components in a battery module includes a laser source configured to emit a laser beam onto a workpiece having a first battery module component and a second battery module component. The system also has an actuator coupled to the laser source and configured to move the laser beam along a first axis and a second axis and a controller electrically coupled to the laser source and the actuator. The controller is configured to send a signal to the laser source and the actuator to form a sinusoidal lap weld on a surface of the workpiece, such that the first battery module component is electrically coupled to the second battery module component.
US11400544B2 Selective laser melting (SLM) additive manufacturing
An in-situ monitoring device for selective laser melting (SLM) additive manufacturing may include at least one coherent electromagnetic wave source to produce a detection beam, an interferometer interposed between the electromagnetic wave source and a target detection area, a photodetector to detect displacement measuring interference between electromagnetic waves from the electromagnetic wave source and reflected electromagnetic waves from the target detection area through the interferometer, and control logic to cause the detection beam to follow a print path of a material forming laser at a distance behind the material forming laser. The detection beam is placed on a laser-melted and at least partially solidified portion of a layer of a three-dimensional (3D) object formed by the material forming laser.
US11400543B2 Device for protecting laser optics
A device for the protection of laser optics or to their lifetime increase. The device for the protection of laser optics comprises a housing arranged below a laser optics housing with a connection for the supply of a cutting gas, and on the opposite side to the laser optics outlet nozzle for the cutting gas and a pressure-resistant protective glass on the side of the laser optics and a process-side protective glass, which is arranged between the nozzle and pressure-resistant protective glass available.
US11400541B2 Method for production of a component by atomic diffusion bonding
A method for producing a component from two plates, which are electrically isolating, at least one is optically transparent, and between them at least one planar conductor section and at least one isolator section are formed, comprises bonding the plates at mutually facing bonding faces, wherein a metal layer is arranged therebetween, and processing the metal layer by local heating using laser radiation such that the metal layer is converted into the at least one isolator section in a part region, and the at least one conductor section is formed adjacent thereto. To form the at least one isolator section, the light path of the laser radiation and the component are moved relative to each other to convert the metal layer into the at least one isolator section over a line or area. Bonding faces of metallic bond layers are polished. The plates are bonded by atomic diffusion bonding.
US11400540B2 Different material joining method
An iron rivet including a head and a shank, an aluminum plate, an iron plate, and first and second electrodes are prepared. A sandwiching step of sandwiching the rivet, the aluminum plate, and the iron plate between the first electrode and the second electrode, a penetration step of performing pressurization and current application by the first and second electrodes so that the shank penetrates through the aluminum plate, and a forming step of performing pressurization and current application by the first and second electrodes so that a nugget is formed between the shank and the iron plate are included. In the penetration step, the pressurization and current application is performed while air is blown to a side face of the shank so that the air hits a region around a boundary between the shank and the aluminum plate.
US11400538B2 Articulated welding robot
Provided is an articulated welding robot that includes an articulated arm in which a plurality of arm parts are linked via a drive shaft. A welding wire is disposed along the articulated arm. In at least one of the arm parts a depression is formed that forms a hollow on the inner side of the arm. At least a portion of the welding wire is accommodated in the depression.
US11400536B2 Metal laminating and modeling method
In a metal laminating and modeling method, a three-dimensional modeled object 10 having a main surface 12 and an outer circumferential surface 13 is modeled by sequentially laminating a plurality of metal layers 11m. The metal laminating and modeling method has a metal layer formation step of forming the metal layers 11m by forming a plurality of weld beads 100 so as to be arranged in a horizontal direction on a table 2, and a first end portion weld bead formation step of inclining the table 2 such that a target surface 2f faces in a first inclination direction and forming first end portion weld beads 100a so as to overlap, among a plurality of center weld beads 100c, the center weld beads 100c located at an uppermost end in a vertical direction Dv.
US11400532B2 Process for producing a plate heat exchanger and plate heat exchanger
A plate heat exchanger has two metal plates brought into abutment, with a solder material between the plates. The plates are heated up to a first temperature. The plates are placed into a mold, the mold surfaces of which have cavities for envisaged channel structures. Channel structures are formed by local internal pressure forming of at least one plate under pressurization by the tool. The plates are heated up to a second temperature. The plates are solder bonded at the abuted surfaces. A plate heat exchanger has two metal plates, wherein channel structures have been formed in at least one plate and the plates are bonded to one another by soldering away from the channel structures. Eutectic microstructures having a longest extent of less than 50 micrometers are formed in the solder layer.
US11400531B2 Dust removal arrangement for an engine-driven tool
The present disclosure relates to engine-driven tool (1) comprising a rotatable work tool (2) and an engine (4) for propelling a first driving pulley (28) via a clutch wheel (30) comprised in a power transferring unit (27) and having an outer edge. The first driving pulley (28) and the clutch wheel (30) arc arranged to rotate around a common driving axis (38). The power transferring unit (27) comprises an endless drive belt (9) that is arranged propel the rotatable work tool (2) when the first driving pulley (28) is propelled. A fan arrangement (13) is arranged to convey air front a dust channel (11) formed between a shielding cover (8) and the rotatable work tool (2), and comprises a fan turbine (26) that is connected to a fan pulley (29) connected to the drive belt (9) is arranged to propel the fan pulley (29). A first overlap line (50) extends along the outer edge (52) of the clutch wheel (30), perpendicular to the extension of the common driving axis (38), the first overlap line (50) further extending via the fan turbine (26).
US11400530B2 Chainsaw and method
Herein a chainsaw (1) is disclosed comprising a guide bar (3) and a chain (5) moveably arranged around the guide bar (3). The chainsaw (1) comprises an motor (9) comprising a motor shaft (11), wherein the motor (9) is configured to drive the chain (5) via the motor shaft (11). The chainsaw (1) further comprises a tension estimation arrangement (13) configured to sense a load on the motor shaft (11), and configured to estimate the tension of the chain (5) around the guide bar (3) on the basis of the sensed load on the motor shaft (11). The present disclosure further relates to a method of estimating tension of a chain (5) of a chainsaw (1).
US11400529B1 Single point rifling tool
A single-point rifling tool including a rifling head with a lateral opening, a hook ramp stationarily secured at a first end of the lateral opening, and a cutting tool movably secured at a second end of the lateral opening. The cutting tool is movable along an angled surface of the hook ramp between a retracted position and a cutting position so as to perform a rifling operation in only a single direction through a gun barrel so as to perform a rifling operation in only a single direction through a gun barrel.
US11400526B2 Clamping jaw assembly and drill chuck
The present disclosure provides a clamping jaw assembly and a drill chuck, which solve technical problems of complex structure, small clamping range, poor clamping effect, and high cost of the existing clamping jaw assembly. The clamping jaw assembly includes a first clamping jaw and a second clamping jaw, both of which include a screwing section, an outer surface of each screwing section is arranged with a thread, a top end of each screwing section is arranged with a clamping section, the screwing section is fixedly connected with corresponding clamping section. An inner side of the clamping section of the first clamping jaw includes a first clamping part, and an inner side of the clamping section of the second clamping jaw includes a second clamping part matched with the first clamping part. The present disclosure can be widely used in fields of electric tools, machine tool accessories and medical equipment, etc.
US11400522B2 Self-locking hollow shaft clamping mechanism
This invention concerns a clamping device for firmly holding a part to be clamped at a clamping recess in which the clamping device is arranged. The clamping device comprises a collet with a first external protrusion for engagement with an internal recess in an inner peripheral area of the part that is to be clamped and with a second external protrusion for engagement with an internal recess in an inner peripheral area of the clamping recess. At least one of the first external protrusion or the second external protrusion comprises a first external taper or a second external taper for pulling the part to be clamped axially into the clamping recess by a radial outward movement of the collet or a section of the collet and an operation stud including an external tapered section for effecting the radial outward movement of the collet. The connection between the operation stud and the collet is self-locked and pre-loaded after a clamping movement of the operation stud in axial direction that locks and pre-loads the external taper of the operation stud and the collet or a part between the collet and the operation stud with each other. The invention includes a method for a part to be clamped in a clamping recess.
US11400518B2 Additive layer manufacturing apparatus with process monitoring facility
Additive layer manufacturing apparatus utilizing a housing, which bounds a vacuum chamber and has a window for monitoring a region of the chamber in which additive layer manufacturing is to be carried out, and an electron beam column for generating an electron beam and transmitting the beam through the chamber to the region for action on successive layers of fusible powder material, particularly metallic material, to produce an article therefrom. In order to combat the problem of deposition on the window of metal material escaping from the layer as gaseous phase constituents with a boiling point below the melting point of the material, an optical element is arranged in the chamber to intercept such liberated gaseous phase constituents, which in a vacuum environment in the chamber travel along an optical path between the region and the window, and optical element heating means substantially preventing condensation of the intercepted constituents.
US11400515B2 Method of manufacturing a component using a sinter joining process
The production of engine parts with a complex geometrical structure. More particularly, a method for producing a complex part, comprising making available a first component, having a thermal expansion coefficient of the first component; a first joining surface; and a first bearing surface; making available a second component, having a thermal expansion coefficient of the second component; a second joining surface; a second bearing surface; and making available a jacket element, having a thermal expansion coefficient of the jacket element; and a jacket-element bearing surface; and heating the first component, the second component and the jacket element from a first temperature to a second temperature in order to carry out a joining process on the first component and the second component. Furthermore, a part, in particular for a gas turbine engine for an aircraft, and to a gas turbine engine of this kind.
US11400514B2 Sintering tool and method for sintering an electronic subassembly
Sintering tool (10) with a cradle for receiving an electronic subassembly (BG) to be sintered, characterized by at least one support bracket (20), arranged at two locations opposite the cradle, for fixing a protective film (30) covering the electronic subassembly (BG).
US11400512B2 Coated sand, production method for same, and production method for casting mold
Provided are: a coated sand having improved fluidity and being capable of improving a filling rate of a casting mold to be obtained; and a coated sand for advantageously manufacturing a casting mold having excellent strength, which coated sand provides a casting mold with good mold-releasability and collapsibility, gives cast products a favorable casting surface, and effectively improves sand adhesion on cast products. The coated sand is formed as a dry granular material having fluidity at room temperature, in which the surface of a refractory aggregate is coated with a solid layer of a water-soluble inorganic binder, and spherical particles of silicone resin having binder-repellency exist on the surface of the binder layer, or form a layer on the surface of the binder layer, a part of the spherical particles being not covered with the water-soluble inorganic binder and being exposed.
US11400509B2 Shell with expandable bubble and tooling therefor
A shell including a central panel with an expandable bubble disposed thereon is provided. The use of an expandable bubble allows for an expandable rivet button and thereafter an expandable rivet that has an enhanced overlap of a tab body. Such an expandable rivet allows for the use of a metal sheet with a thinner base thickness.
US11400508B2 Outward direction pipe fitting swage machine systems and methods
Techniques for implementing and/or operating a system that includes a pipe fitting to be secured to a pipe segment, in which the pipe fitting includes a grab ring having a grab notch and a fitting jacket to be conformally deformed around tubing of the pipe segment to facilitate securing the pipe fitting to the pipe segment. The system includes a swage machine, which includes a grab plate having a grab tab that matingly interlocks with the grab notch to facilitate securing the pipe fitting to the swage machine, a die plate including a die that opens away from the grab plate, and a swaging actuator secured to the die plate. The swage machine operates the swaging actuator to move the die plate over the fitting jacket in an outwardly axial direction away from the grab plate to facilitate conformally deforming the fitting jacket around the tubing of the pipe segment.
US11400504B2 Molded body manufacturing method
A method for producing a molded article includes the steps of: preparing a first steel plate and a second steel plate. The first steel plate and the second steel plate are joined to each other, thereby preparing a joined steel plate. The joined steel plate is heated at a temperature between 910° C. and 950° C. The heated joined steel plate is then subjected to hot-press molding, thereby preparing an intermediate molded article; and cooling the intermediate molded article, wherein the first steel plate has a tensile strength (TS) higher than that of the second steel plate.
US11400502B2 Edge leveler with offset rollers
An edge leveler for leveling an edge of a plate includes a first frame, a plurality of first rollers rotatably mounted along the first frame; a second frame, and a plurality of second rollers rotatably mounted along the second frame. The second rollers are offset relative to the first rollers. A width of a gap between an adjacent pair of first and second rollers on a first end portion of the edge leveler is greater than a width of a gap between an adjacent pair of first and second rollers in a middle portion of the edge leveler.
US11400500B2 Method for converting wire rod of nonferrous metals and alloys thereof to wire with high elongation and in the annealed state
A method for converting wire rod of nonferrous metals and alloys thereof to wire with high elongation and in the annealed state, wherein the reduction in diameter in order to pass from wire rod to wire is carried out by way of a plastic deformation process. The temperature of the metal subjected to plastic deformation is controlled in order to have, at the end of the plastic deformation process, the wire at a temperature higher than or equal to the recrystallization temperature. This avoids the thermal treatment of annealing, necessary in conventional production techniques, achieving a considerable saving in production costs and a wire with characteristics similar to those of a wire subjected to annealing.
US11400494B2 System for processing objects with particulate contaminants
A system for processing objects with particulate contaminants includes a processing station having a holder for holding an object to be processed. The system also includes a suction means in fluid communication with the processing station for removing particulate contaminants from the processing station.
US11400491B2 Systems and methods for dynamic sortation of objects
An automated shuttle sorter is disclosed that includes a carriage that is movable from a load position at which the carriage may be loaded, and at least two destination locations into which any contents of the carriage may be provided from the carriage.
US11400484B2 Fan blade and fabricating method thereof
A fan blade and a fabricating method thereof are provided. The fan blade includes a rough coating layer on a surface thereof. The rough coating layer includes a plurality of recessed regions. A maximum depth of recess of the recessed regions is between 50 μm to 130 μm.
US11400482B2 Device and method for discharging liquid material
A discharge device and method can eliminate the influence of pump pulsation while temperature reduction of liquid material is minimized. The discharge device includes a nozzle (19) having a discharge port (28) a valve seat (31) having a communication bore (30) communicating with the discharge port, a liquid chamber (33) extending vertically, a needle (4) for opening and closing the communication bore of the valve seat, and a circulation flow passage through which the liquid material is supplied to the liquid chamber. The device further includes a rod-shaped flow passage formation member (34) provided with an outer flow passage (36) having a top opening (40) formed at an upper end and a bottom opening (41) formed at a lower end, and with an inner flow passage (35) having a bottom opening (41) in communication with an outer flow passage and a top opening (38).
US11400481B2 Liquid discharge device, application device with said discharge device, and application method
A liquid discharge device to discharge a liquid material stirred near a metering chamber, an application device and an application method using the application device. A liquid discharge device includes a storage unit including a storage container storing a liquid material, and a stirrer drive mechanism; a discharge unit including a metering chamber to be filled with the liquid material, a plunger sliding in close contact with an inner peripheral surface of the metering chamber, a nozzle in communication with the metering chamber, and a switching valve between a first position at which the storage container and the metering chamber are communicated with each other, and a second position at which the metering chamber and the nozzle are communicated; and a connection flow path through which the storage container and the metering chamber are communicated, The stirrer drive mechanism is separable from the storage unit.
US11400479B1 Adhesive applicator control system
An apparatus for coating carpet webs in a coating apparatus with varying adhesives includes a controller, one or more sensors for detecting a volume of a puddle of the adhesive pooled in front of an application roller, and an electronic valve in fluid communication with each of a plurality of mixers. The electronic valve directs flow of the adhesive from any of the mixers to the coating apparatus. To switch from one of the adhesives to new adhesive as a next carpet web passes through the coating apparatus, the controller calculates a remaining length of the carpet web that can be coated with the adhesive in the puddle of adhesive based on the volume of the puddle, so that the puddle of the adhesive coats the carpet web, and then proximate a seam to the next carpet web, the new adhesive begins to coat the next carpet web.
US11400477B2 Reversible nozzle in ultrasonic atomizer for clog prevention
A nozzle for an atomizer includes a plate, a piezoelectric actuator, a body, and a connector. The plate defines an aperture. The actuator is configured to oscillate the plate. The body supports the plate. The connector is configured to reversibly mount the body to the atomizer in a first orientation and in a second orientation. In the first orientation, fluid exits the nozzle along a first axial direction through the aperture. In the second orientation, fluid exits the nozzle along an opposite axial direction through the aperture.
US11400474B2 Liquid dispenser with bottle ventilation
Liquid dispenser having a liquid store and a discharge device fitted thereto and having a discharge opening. The discharge device has a pump device with a pump chamber variable in terms of volume and connected at an input side in a communicating manner to the liquid store and at an output side in a communicating manner to the discharge opening. The pump device conveys liquid from the liquid store to the discharge opening. The discharge device has a ventilation channel, by which an incoming air flow is enabled for pressure compensation between the liquid store and a surrounding atmosphere. The ventilation channel has a ventilation valve openable by manual actuation of the pump device and closed when the pump device is not actuated. Further, the ventilation channel has a capillary channel portion through which the incoming air flow reaches the liquid store.
US11400468B2 Gas-liquid two-phase flow atomizing nozzle
A gas-liquid two-phase flow atomizing nozzle includes a nozzle core, an outer sleeve, and an atomizing body. An inner cavity of the nozzle core consists of an inlet tapered section, a jet flow section, and an outlet diffusion section. The outlet diffusion section of the nozzle core is connected to an atomizing body mixing chamber. The jet flow section of the nozzle core is in communication with external atmosphere through a core air inlet hole, an air inlet buffering chamber, and a sleeve air inlet hole.
US11400463B2 Dosing device for dosing a granular material, spraying device and method for applying a granular material to a substrate
A dosing device for dosing a granular material containing a reservoir for storing the granular material, a dosing disc, and a suction device and a spraying device containing such a dosing device and a method for applying a granular material to a substrate.
US11400457B2 Solid state drive media destroyer
Disclosed is an apparatus for destroying the operational aspects and electronic media of a Solid State Drive (SSD) yet maintaining the physical shape of the SSD for identification. The apparatus includes a crusher box having counter-rotating rollers that are intermeshed to provide a high speed feed of an SSD wherein teeth formed on the rollers render the electron media non-accessible and impart a distinctive waffle like appearance for ease of identifying destroyed SSD's. A VFD-PID controller is used to vary the speed of an electric motor 50 with the PID having a feedback signal that allows for various target values to be set.
US11400456B2 Apparatus and process for producing surface-worked granular product
A surface-worked granular product is produced by supplying raw granular material to a cylindrical retainer having apertures and retaining sites, floating the granular material by suctioning air from the cylindrical retainer, rotating a rotary working device installed in the cylindrical retainer, and contacting working protrusion protruding from the working device with the granular material to remove foreign substances and to perform surface-working of the granular material so as to form a rough surface without causing degeneration, denaturation or substantial removal of useful ingredients, wherein the surface-worked granular product has surface characteristics different from raw granular material.
US11400453B2 Reagent packaging devices and uses thereof
The present disclosure relates to new types of fluid packaging devices and methods of making and using such fluid packaging devices. In various embodiments, the present disclosure provides devices, systems, and methods for packaging fluids. In various embodiments, the present disclosure provides a device including a storage compartment; a fluid stored in the storage compartment; a first aperture on the storage compartment; and a second aperture on the storage compartment. The first aperture is initially sealed or closed before the use of the device and configured to be opened to receive a pneumatic pressure. The second aperture is initially sealed or closed before the use of the device and configured to be opened to allow the fluid to exit or enter the storage compartment via the opened second aperture.
US11400450B2 Method and systems for microfluidic logic devices
A microfluidic system includes a substrate, a set of input ports coupled to the substrate, and a set of output ports coupled to the substrate. The microfluidic system also includes a microfluidic processing system coupled to the substrate and including a plurality of processing sites. The microfluidic processing system is coupled to the set of input ports and the set of output ports. The microfluidic system further includes one or more microfluidic logic devices coupled to the substrate and operable to control at least a portion of the microfluidic processing system.
US11400445B2 Pipetting method and pipetting device
A method is disclosed for controlling at least one of aspirating and of dispensing a liquid dose or of producing a liquid dose in a pipette or in receptacle, the method having the steps of first loading a first pipette with a first working medium at a first pressure having a first sign with respect to a reference pressure, thereby dispensing the liquid dose into the receptacle or aspirating the liquid dose into the first pipette, second loading a second pipette with a second working medium at a second pressure having a second sign with respect to the reference pressure, thereby dispensing the liquid dose into the receptacle or aspirating the liquid dose into the second pipette, discharging a pressure in the first working medium through a controlled valve arrangement to the reference pressure between first and second loadings. A pipetting device is also disclosed.
US11400444B2 Functionalized polyolefin capillaries for open tubular ion chromatography
Open tubular capillary columns for liquid and ion chromatography, based upon an ionically impermeable polyolefin capillary having a bore with a sulfonate-group- or amine-group-functionalized internal surface. The capillary columns may include a coating of ion exchanging nanoparticles electrostatically bound to the functionalized internal surface. The capillary columns may be made by exposing the interior surface to a sulfonating reagent comprising chlorosulfonic acid (ClSO3H), preferably from 85 wt % to 95 wt % chlorosulfonic acid at a process temperature of 20 to 25° C. The interior surface may be subsequently exposed to an asymmetrical diamine to form a sulfonic mid-linkage to the diamine, i.e., to form a sulfonamide-linked, amine-group-functionalized internal surface. The coating may be provided by subsequently exposing the interior surface to an aqueous suspension of ion exchanging nanoparticles to electrostatically bond the ion exchanging nanoparticles to the functionalized internal surface.
US11400442B2 Process for producing a VPO catalyst
The disclosure relates to a process for producing a VPO catalyst containing molybdenum and a vanadyl pyrophosphate phase, which comprises the steps: a) provision of a reaction mixture comprising a V(V) compound, a P(V) compound, an Mo compound, a reducing agent and a solvent, b) reduction of the V(V) compound by means of the reducing agent at least in parts to give vanadyl hydrogenphosphate in order to obtain an intermediate suspension, c) filtration of the intermediate suspension from step b) in order to obtain an intermediate, d) drying of the intermediate at a temperature of not more than 350° C. in order to obtain a dried intermediate and e) activation of the dried intermediate at a temperature above 200° C., characterized in that not more than 0.2% by weight of water, based on the weight of the reaction mixture, is present in step a) and no water is withdrawn during the reduction in step b). The disclosure further relates to a VPO catalyst which is able to be produced by the process of the disclosure and also a catalyst containing the molybdenum-containing vanadium-phosphorus mixed oxide.
US11400441B2 Honeycomb filter
A honeycomb filter includes a pillar-shaped honeycomb structure having porous partition walls provided, surrounding a plurality of cells which serve as fluid through channels extending from an inflow end face to an outflow end face, and porous plugging portions provided either at the ends on the inflow end face or the outflow end face of the cells, wherein the plugging portions are composed of a porous material, the honeycomb structure has a central region and a circumferential region, and a ratio of an area of the circumferential region with respect to that of the central region ranges from 0.1 to 0.5, a plugging length L1 in the cell extending direction of a central plugging portion in the central region is larger than a plugging length L2 of a circumferential plugging portion in the circumferential region, L1 ranges from 7 to 9 mm, and L2 from 3 to 6 mm.
US11400431B2 Composition for soft anti-release moisture absorbent
A moisture absorbent product prepared according to the present invention is characterized by adjusting a composition ratio of a metal chloride, a metal oxide, a cellulose derivative, and a lipid to a specific range, thereby suppressing corrosion, rust, external leakage of a product due to moisture release in an environment such as high temperature while maintaining a high moisture absorption rate, and minimizing a volume change due to moisture absorption. Thus, the moisture absorbent product can be usefully used as a moisture absorption product embedded in a vehicle lamp.
US11400424B2 Micro-bubble acquisition apparatus
A micro-bubble acquisition apparatus is disclosed including a first body in which a water inlet channel, a water outlet channel, a vortex cavity communicating the water inlet channel with the water outlet channel, and an air inlet channel communicated with the vortex cavity are provided. The vortex cavity has an axis offset from an axis of the water inlet channel, the vortex cavity is provided with a water inlet communicated with the water inlet channel, and the water inlet is arranged at a side of the axis of the water inlet channel away from the axis of the vortex cavity.
US11400422B2 Ceramic support, zeolite membrane complex, method of producing zeolite membrane complex, and separation method
A support is a porous ceramic support for supporting a zeolite membrane. The hydraulic conductivity of the support is less than or equal to 1.1×10−3 m/s. In the support, the total content of alkali metal and alkaline earth metal in a surface part within 30 μm from a surface in a depth direction perpendicular to the surface is less than or equal to 1% by weight.
US11400419B2 Method and apparatus for passively bubbling gas through liquid
Methods and apparatuses for adding gas bubbles to a tank containing liquid at locations that allow the bubbles to rise to the top of the tank are disclosed. One embodiment comprises a membrane filtration system connected to a gas source and a drain. The membrane filtration system draws gas into the system from the gas in response to a reduced pressure profile created by opening a drain. The gas may be air supplied at atmospheric pressure.
US11400408B2 Compact regeneration of liquid desiccant
A method for regenerating liquid desiccant is described herein. The method includes co-currently contacting a rich desiccant stream including water with a stripping gas within a co-current contacting system such that the stripping gas removes at least a portion of the water from the rich desiccant stream, producing a wet stripping gas and a lean desiccant stream. The method also includes removing the water from the wet stripping gas within a stripping gas separation system, regenerating the stripping gas, and recirculating the stripping gas to the co-current contacting system.
US11400397B2 Filter medium
The present invention relates to a filter medium comprising a substrate and a fine fiber layer on top of the substrate, wherein the substrate comprises a first layer comprising first fibers having a first average diameter and a first maximum fiber length; a second layer comprising second fibers having a second average diameter and a second maximum fiber length; and a third layer comprising third fibers having a third average diameter and a third maximum fiber length; wherein the boundary area between the first and the second layer forms a first blended area comprising first and second fibers; and the boundary area between the second and the third layer forms a second blended area comprising second and third fibers; and wherein the first and the third average diameters are each larger than the second average diameter.
US11400396B2 Filter element with air-bleed conduit
A filter element includes a first end cap, a second end cap, and an intermediate end cap disposed between the first end cap and the second end cap. A ring of first filter media circumscribing a first central cavity is disposed between the first end cap and the intermediate end cap. A ring of second filter media is disposed between the intermediate end cap and the second end cap. The filter element also includes an air-bleed conduit axially extending through the first central cavity and comprising a first portion integrally formed with the first end cap and a second portion integrally formed with the intermediate end cap and configured to connect to the first portion thereby forming a conduit for transmitting fluid.
US11400393B2 Filtration system
A filter for filtering liquid, comprising: a cylindrical housing; and a multiplicity of discs positioned perpendicularly to a height of the cylindrical housing, each of the multiplicity of discs comprised of a first number of cassettes, wherein each cassette is shaped as a truncated sector having a wide end and a narrow end, the cassettes arranged such that a perimeter of the disc is formed by the wide end of the first number of cassettes, and wherein each of the first number of cassettes is connected to a housing at its wide end, and each cassette having an opening along the wide end, wherein during filtration, liquid being filtered flows over the multiplicity of discs towards the perimeter of the multiplicity of discs.
US11400389B2 Marsdenia cundurango creeper extracts, cosmetic compositions comprising them and cosmetic uses of same
The invention relates to a method for obtaining a Marsdenia cundurango extract containing terpinyl cinnamate compounds, the Marsdenia cundurango bark or wood extracts comprising terpinyl cinnamate compounds obtained by the method, cosmetic compositions comprising them, and the cosmetic uses of same for improving the barrier function of the skin, for improving protection against toxins and detoxification of the skin, and finally for reducing the signs of ageing.
US11400387B2 Dollhouse assembly
A method of forming a dollhouse assembly comprising obtaining a first sidewall, a second sidewall, and a bottom wall. Each of the first and second sidewall and the bottom wall include a top end, a bottom end, a front end, a rear end, a first panel and a second panel superimposed on the first panel and extending between the top end and the bottom end. The first panel and the second panel of each of the first and second sidewall and the bottom wall cooperate to define a sheet receiving space. The method includes connecting the top end of the first sidewall to the top end of the second sidewall; connecting the bottom end of the second sidewall to the right end of the bottom sidewall; and connecting the bottom end of the first sidewall to the left end of the bottom wall.
US11400382B2 Method and device of displaying a progress bar, computing device, and readable storage medium
Techniques of generating and displaying an attention curve relative to a progress bar are described in the present disclosure. The disclosed techniques include sending a request for acquiring a target video that is divided into a plurality of predetermined time period; receiving data comprising a number of comment events and a number of drag progress bar events within each preset time period of the target video; determining an attention value corresponding each predetermined time period based on the number of the comment events and the number of the drag progress bar events within each predetermined time period of the target video; generating an attention curve based on a plurality of attention values corresponding to the plurality of predetermined time periods of the target video; and displaying the attention curve relative to a progress bar, wherein amplitude values of the attention curve relative to the progress bar are in proportion to the plurality of attention values corresponding to the plurality of predetermined time periods of the target video.
US11400380B2 Information processing apparatus and download processing method
A language information retention section retains working language information for specifying a user-selected working language in an information processing apparatus. A download processing section downloads application software into an auxiliary storage apparatus. The download processing section acquires a data region in the auxiliary storage apparatus as needed for an application body and language-dependent files for a working language before the start of an application software download, and then executes the application software download. In a case where the working language used by an application is changed, the download processing section confirms whether or not a data region for language-dependent files for the changed working language can be acquired in the auxiliary storage apparatus 2.
US11400375B2 Object display method and apparatus, storage medium, and electronic device
An object display method is provided for a terminal. The method includes displaying a first object in an object display region in a game interface and, after detecting a first operation performed on the first object, displaying a second object in the game interface in response to the first operation. The first object is used for controlling, in response to a second operation performed on the first object, a game character to perform a first target operation, and the second object is used for controlling, in response to a third operation performed on the second object, the game character to perform a second target operation.
US11400368B2 Method and apparatus for controlling virtual object, and storage medium
The present disclosure provides a method for controlling a virtual object. The method includes: identifying screen areas corresponding to a left virtual sub-interface and a right virtual sub-interface in a virtual interface on a screen of the terminal device; detecting a gesture operation performed in the screen area corresponding to the left virtual sub-interface and detecting a gesture operation performed in the screen area corresponding to the right virtual sub-interface; and controlling a virtual object in the virtual interface to perform an action when a gesture operation is detected in the screen area corresponding to the left virtual sub-interface and the screen area corresponding to the right virtual sub-interface.
US11400364B2 Controller with swappable input controls
A controller device comprises a controller body that includes at least two interface ports and a control information output port. A modular input control that is removably attachable to the controller body includes an interface connector region that communicatively couples the modular input control to any of the at least two interface ports.
US11400363B2 Information processing apparatus, information processing system, controller device, information processing method, and program
An information processing apparatus connected to a controller device equipped with proximity sensors that are provided for at least respective fingers of a user, estimating amounts of bending of the fingers of the user using a first method on the basis of detection results from the proximity sensors, estimating a posture and a shape of a hand of the user using a second method different from the first estimation method, and correcting by using information estimated by the first method, information regarding an amount of movement of each finger in a bending direction in information regarding the posture and the shape of the hand of the user estimated by the second method to generate information relating to the posture and the shape of the hand of the user.
US11400360B1 Electronically controlled detachable motorized track system for sports apparatus
An electronically controlled detachable motorized track system for a snowboard having front and rear baseplates sized to fit in a backpack with right and left motorized tracks having a length extending beyond the front and rear baseplates from proximate the rear of a snowboard to proximate the front of a snowboard and beyond the front and rear baseplates, each adapted for wrapping around drive rollers and freely rotating rear rollers. A hand controller wirelessly controls the tracks.
US11400359B2 Mouthguard with light emitting function
The present invention discloses a mouthguard with light emitting function. The mouthguard with light emitting function includes an occlusion unit which is bitten by teeth between the maxilla and the mandible of a wearer. A front end of the occlusion unit is provided with a protector which includes a holding chamber. The mouthguard also includes a lower cap, which is disposed in the holding chamber of the protector; an electric module, which is disposed in the lower cap and includes a control circuit, light emitting devices and a push button; and an upper cap, which covers the electric module to clip and fix with the lower cap. By pressing the push button, the light emitting devices are activated to emit light, thereby achieving the effect of alerting and highlighting.
US11400356B2 Electronic tracking system with heads up display
Electronic tracking systems are disclosed for assisting users with locating objects in a sporting environment. One such system includes a ball tracking component that tracks a game ball while moving in the sporting environment, and a heads up display that is worn by the user. This heads up display has an electronic display screen with a transparent display area that dynamically displays images within the user's field of view. A processor, which communicates with the ball tracking component and heads up display, is programmed to detect movement of the game ball, and responsively determine launch characteristics and/or flight characteristics of the moving game ball. The heads up display displays the launch/flight characteristics contemporaneous with an object indication adjacent to or superimposed over the moving game ball as the game ball is visible through the transparent display area of the display screen within the user's field of view.
US11400352B1 Golf club heads and methods to manufacture golf club heads
Embodiments of golf club heads, golf clubs, and methods to manufacture golf club heads and golf clubs are generally described herein. In one example, a golf club head may include a body portion including an interior cavity, a filler material in the interior cavity, and a face portion having a front surface, a back surface, a face perimeter defined by a face toe edge, a face heel edge, a face top edge, and a face sole edge. The face portion may further include a first back groove portion on the back surface located proximate to the face toe edge and extending from a location at or proximate to the face top edge toward the face sole edge, a second back groove portion on the back surface located proximate to the face top edge and extending from a location at or proximate to the face toe edge to a location at or proximate to the face heel edge, and a third back groove portion on the back surface located proximate to the face heel edge and extending from a location at or proximate to the face top edge toward the face sole edge. The first back groove portion and the second back groove portion, or the second back groove portion and the third back groove portion may be connected. The first back groove portion, the second back groove portion, and the third back groove portion may be at least partially filled with the filler material. Other examples and embodiments may be described and claimed.
US11400341B2 Hand grip exerciser
A handgrip exerciser device has two pivotally interconnected arms. Each arm has a first end region, a central region and a second end region. Each arm has at its first end region a hand grip. The central region forms a pivot pin receiving area. A pivot pin extends between the two arms enabling the arms to be rotatably connected together. Each arm having at its second end region a mounting portion. A resistance element providing a resistive force against rotational movement of the arms and having first and second ends. A first arm mounting portion supports the first end of the resistance element providing element. A second arm mounting portion supports the second end of the resistance element. An adjustment element adjusts the resistive force applied by the resistance element to the rotation of the two arms around the pivot pin.
US11400337B1 Retractable wall mounted weightlifting bench system
A retractable wall mounted weightlifting bench system for that is extended outwardly from the wall when in use and retracted towards the wall when not in use. The retractable wall mounted weightlifting bench system generally includes a mounting bracket adapted to be attached to a wall, a bench pivotally connected to the mounting bracket that has an extended position and a retracted position, a first support member pivotally attached to the bench and a second support member pivotally attached to the bench. The first surface of the bench is horizontal or inclined when in the extended position to be used as a weightlifting bench. The first surface of the bench is in a substantially vertical position when in the retracted position for compact storage of the bench near the wall.
US11400336B2 Lower body exercise device
An exercise device includes a resilient compression member configured to resist a compressive force from a user, and a resilient tension member configured to couple to opposing sides of the compression member. The resilient tension member is also configured to form a first portion of a loop around the compression member and the user, and resist a tensile force from the user. The exercise device also includes an extension member configured to connect with opposing ends of the tension member to form a second portion of the loop around the compression member and the user.
US11400334B2 Exercise device with a pair of handgrip assemblies
The present disclosure relates to a modular strap-based exercise apparatus, kit, and method of use thereof, and more particularly to an apparatus, kit, and method for modularly connecting components of a strap-based exercise device. In an embodiment, the strap-based exercise apparatus includes one or more infinity loops configured to attach various portions of the exercise apparatus together. The exercise apparatus may be provided as a kit including an elongated member, a grip assembly, and one or more mechanisms for adjusting the length of a strap and connecting straps together.
US11400332B1 Resistance band apparatus, method, and system
A system for selectively adjusting the fixed length of a single, retractable elastic body. The system enables control of the resistivity of the elastic body as well as a definitive determination of a level of force exerted against the single elastic body. The determined level of force is represented on an interface device embodied in a housing for the elastic body. The data associated with the determined level of force can be wirelessly communicated to other users' interface devices or smart devices for facilitating healthy competition between users.
US11400328B2 Hydrant monitoring communications hub
A method of processing measurements of a fluid inside a fluid distribution system includes receiving data wirelessly into a communications hub from a sensing device of a hydrant, the communications hub positioned inside a bonnet cavity of the hydrant, the communications hub including: a PCB; at least one battery in electrical communication with the PCB; and a first antenna in electrical communication with the PCB; a second antenna in electrical communication with the PCB; and transmitting the data to the second antenna.
US11400327B2 Discharge pressure adjustment cartridge that is combined with fire hose pressure relief valve
The present invention relates to a discharge pressure adjustment cartridge that is combined with a fire hose pressure relief valve and, more particularly, to a discharge pressure adjustment cartridge that is combined with a fire hose pressure relief valve, the discharge pressure adjustment cartridge enabling a firefighter to easily control the discharge direction of firefighting water by removing upward force that is generated in the firefighting water in the opposite direction to gravity by discharge pressure.
US11400326B2 Ejector nozzle and use of the ejector nozzle
The invention relates to an ejector nozzle having a liquid-carrying duct and a gas-carrying duct. The gas-carrying duct opens into the liquid-carrying duct upstream of an outlet opening. The insert acting as a flame arrester is positioned in the gas-carrying duct. The insert is configured in such a way that no gas can flow around the insert. The invention furthermore relates to use of the ejector nozzle in a jet loop reactor.
US11400323B2 Protective face coverings
Face coverings that protect the facial T-Zone region (i.e., eyes, nose, and mouth) from airborne transmission of infectious and other harmful particles are disclosed. The face coverings disclosed herein are designed to attach to the temples, frames, and/or the bridge of eyewear, which provides protection for the eyes of the wearer and dispenses of the need to adjust straps traditionally found on face masks. The face coverings may be converted to different configurations depending on the amount of protection and comfort desired by the wearer. For example, the face coverings disclosed herein can convert from a free-hanging position to a more protective configuration in which the mask conforms closely to the face of the wearer.
US11400321B2 Self-contained negative pressure environment device and system
A system configured to create a self-contained negative pressure environment (SCONE) to remove airborne particulates emitted from a patient. The system prevents exposure to pathogenic biological airborne particulates during triage, transportation, and treatment, including aerosol generating procedures (AGPs) and end of life care. This system is directed to a collapsible device having a flexible cover covering two support members, with openings in the flexible cover such that medical professionals can reach in and operate within. The present invention is further adaptable to patients and operating environments of various sizes.
US11400320B2 Multifunctional safety tool
Provided herein are personal safety tools and multifunctional safety tool. The tools have a window striker and a tactical whip on each end of a grip or handgrip. Alternatively, the window striker includes a blade to enable a user to cut through a seat belt. The tool is useful for extricating one's self or another from a vehicle and/or for defending one's self or another from an attacker in an emergency.
US11400319B2 Methods for lifting skin tissue
Methods for treating skin and subcutaneous tissue with energy such as ultrasound energy are disclosed. In various embodiments, ultrasound energy is applied at a region of interest to affect tissue by cutting, ablating, micro-ablating, coagulating, or otherwise affecting the subcutaneous tissue to conduct numerous procedures that are traditionally done invasively in a non-invasive manner. Methods of lifting sagging tissue are described.
US11400314B2 Photon emission detection device and neutron capture therapy system with the same
A boron neutron capture therapy system includes a neutron capture therapy device, a photon emission detection device and a treatment bed. The photon emission detection device includes a detecting portion surrounding the periphery of the treatment bed and detecting gamma rays generated after irradiating a boron-containing drug with neutrons; the detecting portion includes a first detecting portion and a second detecting portion moving away from or close to the first detecting portion so that the detecting portion forms a ring with the radius being increased or decreased; and the ring surrounds the treatment bed. The photon emission detection device for use in the boron neutron capture therapy system can change the radius of the ring, surrounding an irradiated object, of the detecting portion according to the actual condition in the boron neutron capture therapy so as to improve the detection precision of the photon emission detection device.
US11400308B2 Dermatological picosecond laser treatment systems and methods using optical parametric oscillator
Dermatological systems and methods for providing picosecond laser pulses at a plurality of treatment wavelengths, wherein at least one of the wavelengths is provided by an optical parametric oscillator (OPO) capable of providing picosecond laser pulses at a wavelength for treating one or more target tissue types such as a sebaceous gland, sebum, or collagen. In some embodiments, multiple OPOs may be provided to enable a wide range of selectable treatment wavelengths.
US11400307B2 Controllable ocular phototherapy
Embodiments of the present disclosure are directed to a wearable phototherapy eye device. In an example, phototherapy can be controlled by varying an emission property of light emitted from the wearable phototherapy eye device to a user eye. In particular, the wearable phototherapy eye device includes a light source oriented to emit the light towards the user eye. The wearable phototherapy eye device also includes controls, such as electrical, mechanical, and/or electro-mechanical controls, to vary the emission property of the light based on an emission target associated with a sleep phase.
US11400304B2 Portable apparatus for generating an induced low-frequency sinusoidal electric current
A portable apparatus for generating an induced low-frequency sinusoidal electric current in an area of the human body includes four angular magnet sectors inscribed within the same circle, centered on the same axis of rotation, and spaced angularly apart from one another. The polarity of two adjacent angular magnet sectors is opposed, and a motor for rotating at a predetermined speed the angular magnet sectors is about the axis of rotation to generate an induced sinusoidal current at a predefined frequency. Each angular magnet sector includes the same geometrical shape with an internal angular opening of 90°, an external angular opening between 20° and 50°, and two lateral edges defining a radius extending over a distance, which is between one-third and two-thirds of a distance separating the axis of rotation from the free end of the magnet sectors.
US11400303B2 Detecting walking in a wearable cardioverter defibrillator system
A wearable medical includes a walking detector module with a motion sensor that is configured to detect when the patient is walking or running. In embodiments, a parameter (referred to herein as a “Bouncy” parameter) is determined from Y-axis acceleration measurements. In some embodiments, the Bouncy parameter is a measurement of the AC component of the Y-axis accelerometer signal. This detection can be used by the medical device to determine how and/or whether to provide treatment to the patient wearing the medical device. For example, when used in a WCD, the walking detector can prevent “false alarms” because a walking patient is generally conscious and not in need of a shock.
US11400300B2 Systems and methods for cooperative invasive and noninvasive brain stimulation
Methods and systems for optimizing invasive and noninvasive brain stimulation are described herein. In a particular embodiment, methods and systems for a combinatorial, iterative approach to modify behavior are presented wherein deep brain stimulation (DBS) and other brain stimulation therapies are implemented in combination with monitoring the brain activity of an individual to optimize the effectiveness of the combinatorial approach to modify behavior. Methods described herein are iterative and systems described herein are utilized in iterative fashion. In a particular embodiment, modifying behavior provides a therapy for an individual in need thereof.
US11400293B2 Method and apparatus for stimulation
A medical device system and method are disclosed for treating obstructive sleep apnea. The system includes a pulse generator and a medical electrical lead including multiple electrodes carried by a distal portion of an elongated lead body. The method includes advancing the distal portion within protrusor muscle tissue below the oral cavity and delivering electrical stimulation pulses via the electrodes to sustain a protruded state throughout a delivery time period to sustain a protruded state of a patient's tongue throughout the therapy delivery time period. The therapy delivery time period may span multiple respiration cycles.
US11400289B2 Apparatus and methods for predicting therapy outcome
Apparatus and methods are described for use with electrophysiological signal detecting electrodes, and a transcranial magnetic stimulation device. A computer processor drives the transcranial stimulation device to apply one or more pulses of transcranial magnetic stimulation to a subject. Within a given time period of applying one of the one or more pulses of transcranial magnetic stimulation to the subject, the computer processor detects an electrophysiological signal of the subject, using the electrophysiological signal detecting electrodes. At least partially in response thereto, the computer processor predicts an outcome of treating the subject for a neuropsychiatric condition, using a given therapy, and generates an output on an output device in response to the predicted outcome. Other applications are also described.
US11400285B2 Methods and systems for tremor reduction
A tremor-reduction system is provided that delivers electric current to a body region of a subject that is associated with a tremor. A computing device stores received data associated with a tremulous movement of the body region and determines measurements associated with the stored data. If a magnitude of the most recent tremulous movement is the same as or greater than magnitudes associated with prior tremulous movements, characteristics of a subsequent electric current to be applied to the body region may be adjusted.
US11400284B2 Method of transcutaneous electrical spinal cord stimulation for facilitation of locomotion
In various embodiments, non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries are provided. In some embodiments the methods involve administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces locomotor activity.
US11400283B2 Pulse generating device for delivery of electrical pulses to a desired tissue of a mammal
A pulse generating device for delivery of electrical pulses to a desired tissue and configured to be connected to needle electrodes arranged at the desired tissue. The device comprises a determining module configured to determine a primary voltage amplitude of a first pulse and a number of consecutive pulses to be generated. Further, the device comprises a pulse generator configured to generate one or more of the determined number of consecutive pulses such that the generated first pulse has the primary voltage amplitude and that the generated consecutive pulses have a respective voltage amplitude consecutively decreasing between consecutive pulses, whereby an increase in a current value of the generated consecutive pulses above a threshold value is avoided. Furthermore, the device comprises a terminating module configured to terminate generation of the one or more pulses when a value of a total absorbed energy exceeds a threshold value.
US11400281B2 Fixation for implantable medical devices
A tine portion of an implantable medical device includes a hook segment and a distal segment terminated by a tissue-piercing tip, wherein the distal segment extends from a distal end of the hook segment to the tip. The hook segment, which is elastically deformable from a pre-set curvature, for example, defined by a single radius, preferably tapers from a first width thereof, in proximity to a proximal end thereof, to a smaller, second width thereof, in proximity to the distal end thereof, wherein the tip has a width that is greater than the second width of the hook segment. Alternately, the tine portion may include a hook segment that is defined by two radii and a straight section extending therebetween.
US11400279B2 Method and system for assessing laryngeal and vagus nerve integrity in patients under general anesthesia
The system and method of the present invention takes advantage of the laryngeal adductor reflex (LAR), previously thought to be repressed during general anesthesia, for CIONM without placement of an electrode on the vagus nerve.
US11400278B2 Methods and systems for treating hypertension using an implantable stimulator
A method of treating hypertension in a patient includes generating, by an implantable stimulator configured to be implanted beneath a skin surface of the patient, stimulation sessions at a duty cycle that is less than 0.05 and applying, by the implantable stimulator in accordance with the duty cycle, the stimulation sessions to a tissue location associated with the hypertension. The duty cycle is a ratio of T3 to T4. Each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes. The implantable stimulator is powered by a primary battery located within the implantable stimulator and having an internal impedance greater than 5 ohms.
US11400276B2 Systems and methods for pump-assisted blood circulation
Disclosed are systems, devices, and methods that employ a pump to assist or support blood flow. An apparatus for pumping blood may include a pump housing having an outer wall disposed about a longitudinal pump axis, and having an upstream end and a downstream end; a blood flow straightener having a plurality of fins and positioned in the upstream end of the pump housing and secured to the pump housing by the plurality of fins; a diffuser having a plurality of diffuser fins and positioned in the downstream end of the pump housing and secured to the pump housing by the plurality of diffuser fins; and an impeller positioned between the blood flow straightener and the diffuser, and including a plurality of impeller blades. The apparatus may further include a pump drive configured to impart a rotational motion to the impeller by applying a magnetic field.
US11400274B2 Heart support device with directional flow assist
A heart support device for circulatory assistance is disclosed. The device comprises a chamber body (10) defining a chamber having an internal volume configured to be filled with blood. The chamber body (10) has a first opening (12) and the chamber is dimensioned such that the first opening (12) and the chamber are fully disposed within a chamber of the human heart. A dynamic volume body (14) is provided and configured to be inflated or deflated to alternately increase or decrease the interior volume of the chamber. A catheter (16) comprising at least one lumen in fluid communication with the dynamic volume body is configured to deliver fluid to the dynamic volume body to inflate the dynamic volume body. A directional flow structure is configured to direct a flow of blood out of the chamber in a direction substantially aligned with a direction in which the catheter (16) extends.
US11400273B2 Constriction valve
Constriction valves for catheters and method of using constriction valves are presented. The catheter valve has a conduit comprising mesh defining a lumen. The catheter also has a biasing member that is configured to bias the lumen from an open position to a closed position by altering an effective length of the conduit or altering the circumference of the conduit. The biasing member is further configured to change its configuration by changes of intraluminal pressure of the valve. A user can insert a tool into a catheter having a valve by manipulating the valve to expand a substantially closed lumen by compressing the biasing member, twisting the biasing member, or pulling on a cord coupled with the valve.
US11400272B2 Medical treatment system and methods using a plurality of fluid lines
Improvements in fluid volume measurement systems are disclosed for a pneumatically actuated diaphragm pump in general, and a peritoneal dialysis cycler using a pump cassette in particular. Pump fluid volume measurements are based on pressure measurements in a pump control chamber and a reference chamber in a two-chamber model, with different sections of an apparatus being modeled using a combination of adiabatic, isothermal and polytropic processes. Real time or instantaneous fluid flow measurements in a pump chamber of the diaphragm pump are also disclosed, in this case using a one-chamber ideal gas model and using a high speed processor to obtain and process pump control chamber pressures during fluid flow into or out of the pump chamber.
US11400270B2 Delivery adapter
A delivery adapter which may be used as an interface between a syringe and a catheter hub is described.
US11400268B2 Electromagnetically driven tattoo machine and system
A magnetically driven tattoo machine is disclosed, which has a substantially radially symmetric exterior shape and be driven by a sensor-controlled electromagnetic coil. The machine has no oscillating mechanical components, and thus reduces or eliminates vibration. The machine may include a housing mechanically isolated from a needle cartridge or subcomponents that can be disassembled and sterilized. The electromagnet may be controlled by a sensor integral with the coil, housed within the machine, or within an external power supply. The machine may be powered by internal battery or by an external power source. The machine may also be controlled wirelessly.
US11400266B2 Drug delivery methods and systems
A two-part bioactive agent delivery system, the system including a disposable part comprising an agent reservoir, a bolus chamber, the volume of the bolus chamber being less than the volume of the agent reservoir, an agent outlet, and a valve having a first position communicating the agent reservoir with the bolus chamber and a second position communicating the bolus chamber with the outlet; and a reusable part including a valve driver, a power source and control electronics, the control electronics being adapted to control the valve driver to actuate the valve to deliver bioactive agent from the agent reservoir to the agent outlet; the system further having a spring extending between the agent reservoir piston and a surface of the reusable part or of the disposable part to pressurize the agent reservoir when the spring is compressed and the agent reservoir contains a quantity of bioactive agent.
US11400263B1 System and method for selective pressure-controlled therapeutic delivery
A treatment system includes a guide sheath, and a catheter provided with a pressure-controlled element. The pressure-control element preferably includes an expanded configuration adapted to extend across a small feeder vessel branching from the splenic vein. The pressure-control element is positioned with the feeder vessel, and a therapeutic agent is delivered under pressure directly into the feeder vessel, where it is forced to penetrate deep into tissue. Pressure responsive elements for monitoring intravascular pressure are also provided to time delivery of the therapeutic agent for maximum uptake by the target organ. Methods for treating tissues and organs via vascular pathways are provided.
US11400262B2 Guidewire having external coil with sections of different winding pitches and resin coatings
A guide wire includes a core shaft, a coil wound around the core shaft, a distal-end joining region to which a distal end of the core shaft and a distal end of the coil are joined, and a proximal-end joining region to which a proximal end of the core shaft and a proximal end of the coil are joined, and the coil has a sparsely wound portion having a sparser coil pitch than other portions of the coil, the sparsely wound portion being disposed between the distal-end joining region and the proximal-end joining region.
US11400260B2 Catheter insertion device
A tool (10) for inserting a catheter (22) into a body of a patient is provided. The tool (10) comprises: a housing (12, 40, 50) in which at least a portion of the catheter (22) is initially disposed; a needle (16) distally extending from the housing (12, 40, 50), at least a portion of the catheter (22) disposed over the needle (16); a guidewire (32) initially disposed within the needle (16) partially; and an advancement assembly (20) for distally advancing the catheter (22). The housing (12, 40, 50) comprises: a first portion (12A, 42, 52) comprising a distal part (42A, 52A) and a proximal part (42B); and a second portion (12B, 44, 54) engaged with the first portion (12A, 42, 52), wherein the distal part (42A, 52A) of the first portion (12A, 42, 52) is configured to be able to distally slide with respect to the second portion (12B, 44, 54) to release the engagement between the first portion (12A, 42, 52) and the second portion (12B, 44, 54). The advancement assembly (20) includes a safety cap (26) which is initially disposed over the needle (16) and is configured to be locked to the housing (12, 40, 50) when distally sliding to a position of isolating the tip of the needle (16) within the safety cap (26).
US11400257B2 Frictionless catheter
A catheter may include a tubular member having a lumen and an outer surface, a sleeve configured to be positioned in the lumen in a retracted configuration and to evert over at least a portion of the outer surface in an everted configuration, and a filament configured to retract the sleeve into the retracted configuration. The catheter may include an aperture proximal of a distal end, where the filament extends through the aperture from the lumen. A pull member may be on a distal end of the filament. The filament may be looped, coiled, and/or bunched in the catheter when the sleeve is in the retracted configuration. A shuttle may be attached to a distal end of the sleeve, where the shuttle includes a tubular member configured to maintain patency of the sleeve, and the filament engages the shuttle to retract the sleeve into the lumen.
US11400249B2 Breathing assistance apparatus
A nasal cannula assembly is disclosed having a face mount part, in use resting against a user's face, which includes at least one nasal prong capable of being fitted into a person's nares. The cannula assembly also includes a manifold part, in fluid communication with the face mount part, having a single horizontal side gases entry. In particular, this cannula assembly is for supplying heated, humidified gases to a patient suffering from COPD. A tie or lanyard is disclosed for use with a breathing assistance apparatus such as a nasal cannula, face or nasal mask or tracheostomy connector. The tie or lanyard transfers the weight of the conduits supplying gases to the breathing assistance apparatus from the breathing assistance apparatus and distributes it onto the neck of the patient.
US11400248B2 Positive pressure ventilation elbow and related masks, systems, and methods
A positive pressure ventilation (PPV) elbow connects to a PPV mask and a source of pressurized air from a ventilator. The elbow and includes an access valve that opens to provide access to the mouth of the patient without removing the mask and self-seals under pressure from the ventilator.
US11400243B2 Power supply section configuration for an electronic vaping device and electronic vaping device
A power supply section for an e-vaping device includes a sensor housed in a housing, a sensor holder holding the sensor, the sensor holder disposed in the housing to divide the housing into a first portion and a second portion, and the sensor and the sensor holder configured to substantially prevent air flow from the first portion into the second portion, and a power source disposed in the second portion. The construction of this unit insures that gases that may be produced by outgassing of the battery cell will be vented to the environment and that those gases will be isolated from the air that is mixed with the vaporized e-liquid and inhaled by the user.
US11400231B2 Supplemental device for attachment to an injection device
A supplemental device for attachment to an injection device, the supplemental device having a housing containing at least two electromechanical switches each having an open state and a closed state and a protrusion associated with each switch configured to protrude from the housing so as to contact a rotatable surface of the injection device while the supplemental device is attached to the injection device; and a processor arrangement configured to detect a change in the state of each of the switches; and to determine a direction of rotation of the rotatable surface of the injection device from the detected state changes.
US11400226B2 Injector premature activation blocking mechanism
An injector includes a housing and an activation button assembly movably mounted thereto and translatable from an unactuated position to an actuated position. A cartridge door is configured to receive therein a cartridge containing a substance to be dispensed, and is movably mounted to the injector housing between open and closed positions. A deflectable interference member is mounted within the injector housing and, in a resting position, blocks movement of the activation button assembly from the unactuated to the actuated position thereof. The activation button assembly is configured to activate the injector when in the actuated position, and is movable from the unactuated position to the actuated position solely upon deflection of the interference element out of the resting position thereof. The cartridge door, when in the closed position thereof and having the cartridge received therein, deflects the interference element out of the resting position thereof.
US11400225B2 Piston rod brake mechanism
The invention provides a pen-type injection device (1) with a piston rod brake mechanism for improving the determination of an expelled dose.
US11400224B2 Safety arrangement and medical delivery device
A safety arrangement for being used in a medicament delivery device, comprising a container holder with a body section and a flange seat and a shell. The container holder is arranged to receive a container with a longitudinal body at one end passing over into a distal flange and at an opposite end passing over into a proximal orifice via a shoulder, such that the distal flanges of the container contacts the flange seat of the container holder. Moreover, the container holder is arranged in the shell such that the container holder is movable in a proximal direction in relation to the shell. A blocking element is arranged between the shell and the container holder. A blocking initiating structure is arranged to reposition the blocking element when the container holder is moved in the proximal direction in relation to the shell from a first position to a second position.
US11400222B2 Syringe carrier
Described is a syringe carrier comprising a body adapted to receive a barrel of a syringe. The body includes two sections having distal ends with shoulder sections. The shoulder sections are adapted to engage a circumferential gap between the barrel of the syringe and a needle shield covering a needle of the syringe.
US11400210B2 Keep vein open infusion flow control device
Keep vein open (KVO) infusion flow control devices are provided. The KVO infusion flow control device couples to intravenous (IV) tubing and includes a flow controller that provides a full open fluid flow rate through an outlet portion of the IV tubing when the flow controller is in an open position, and a KVO fluid flow rate through the outlet portion of the IV tubing when the flow controller is in a KVO position. Visual indicators are disposed on the KVO infusion flow control device.
US11400209B2 Infusion device system and apparatus
An infusion device. The infusion device includes a top portion comprising an introduction needle, and a bottom portion comprising a cannula, the top portion removably attached to the bottom portion, wherein the introduction needle is used to insert the cannula, and wherein after insertion, the top portion is removed from the bottom portion.
US11400206B2 Syringe packaging system
A syringe packaging system that includes a tube and a cap for enclosing a pre-filled syringe is disclosed. The tube includes a proximal end, a closed distal end, and a sidewall extending between the proximal and closed distal ends. The sidewall includes an injection molding gate. In one embodiment, a film is securable to a portion of the tube and a portion of the cap to connect the tube and the cap with the pre-filled syringe enclosed within the cap and the tube.
US11400199B2 Bioartificial liver based on human iPSCs-derived hepatocyte-like cells and multilayer porous bioreactor
A bioartificial liver (BAL) based on human induced pluripotent stem cells (iPSCs)-derived hepatocyte-like cells (HLCs) and a multilayer porous bioreactor is provided. The plasma separation/retransfusion loop part includes a blood input pipe, an exhaust pipe spring clamp, a blood input peristaltic pump, a heparin pump, a plasma separation column, a first pressure monitor, and a heater. The cell reactor/plasma component exchange double-loop part includes a plasma input peristaltic pump, and a semipermeable membrane exchange column, a plasma exchange peristaltic pump, a red blood cell (RBC) pool, a membrane lung, a multilayer porous bioreactor, a second pressure monitor, and a third pressure monitor arranged in a 37° C. dedicated incubator. An outlet of the third pressure monitor and a blood cell outlet are connected to an inlet of the first pressure monitor, and then connected to the heater and a blood output pipe in sequence.
US11400198B2 Hemodialysis catheter with corrugated tips
Hemodialysis catheter with corrugated tips. Includes elongated body having first and second distal end regions terminating in tips opened to lumens extending continuously along both elongated body and distal end regions. Each tip includes a tip edge extending from tip tubular wall and surrounding tip opening. Each tip tubular wall has a corrugated configuration with at least two grooves, including outer and inner grooves, merging into the tip edge. Grooves may have same or different lengths, widths, or/and spatial configurations. Distal end regions may be elastic and configured to have non-stressed form when divergent, via diverging angles, from elongated body longitudinal axis, and may be rotationally symmetric relative to the axis. In some embodiments, tip inner wall and hollow outer surfaces merge into a corrugated form having alternating grooves and ridges along distal ends of the tip, that enable the catheter to facilitate active lateral or frontal fluid traversability therethrough.
US11400197B2 Devices for percutaneous PA-LA cannulation and methods of delivering and using the same
A pulmonary artery (PA) via trans-septal to left atrial (LA) percutaneous dual lumen cannulation system which reduce the pressure of the right ventricle provides drainage of pulmonary artery blood with bypassing the lung while return the blood to the Left Atrium (LA) without the need for thoracotomy for a wearable pump less extra corporeal lung assist (pECLA) to remove CO2, pump less extra corporeal membrane oxygenation (ECMO), para-corporeal pump driven CO2 removal, extra corporeal CO2 removal (ECCO2R) pump driven, para-corporeal pump driven membrane oxygenation, or extra corporeal membrane oxygenation (ECMO) with extra-corporeal pump. By establishing percutaneously a shunt with a dual lumen cannula between PA and LA using the PA-LA pressure gradient as the driving force for the blood flow through the drainage lumen, CO2 removal device, or oxygenator and return cannula lumen in the vascular system.
US11400194B2 Fluid management and measurement systems, devices, and methods
A medicament preparation system includes a disposable cartridge with a flow path. Various sensors may be placed on the cartridge to measure qualities of the fluid flowing through the flow path. The sensors are placed in precise locations using various approaches that make manufacturing of the cartridge efficient and repeatable. A drain line that is susceptible to fouling may be preattached and various approaches are used to remove or reduce the fouling. An elastomeric contact can also be present in the medical preparation system and used in a conductivity measurement subsystem.
US11400187B2 Therapeutic nanoparticles for treating vascular diseases
A variety of nanoparticles or microparticles may be used to treat diseases such as restenosis or blood clots. For example, a nanoparticle or microparticle may include a core having a biodegradable polymer, an exterior having hydrophilic moieties. and a therapeutic agent. The nanoparticles may include targeting moieties that target the nanoparticle or microparticle to an arterial lesion. The nanoparticle or microparticle may include an exterior shell around the core to increase stability of the nanoparticle or microparticle. The nanoparticle or microparticle may include a magnetic particle to allow targeted delivery of the nanoparticle or microparticle via a magnetic field. The nanoparticles or microparticles may be coated on a medical device, such as a catheter balloon or a stent, or may be delivered systemically or locally to patients in need thereof.
US11400186B2 Drug delivery system for the delivery of antiviral agents
This invention relates to novel implant drug delivery systems for long-acting delivery of antiviral drugs. These compositions are useful for the treatment or prevention of human immunodeficiency virus (HIV) infection.
US11400180B2 Hemostatic pad assembly kit and method
The present invention relates generally to agents and devices for promoting hemostasis and tissue sealing and, more particularly, to hemostatic pads comprising bioabsorbable scaffolds that can deliver lyophilized hemostasis promoting proteins, such as fibrinogen and thrombin, to a wound site or injured organ or tissue.
US11400177B2 Germicidal lighting
Apparatus, methods and instructions for disinfecting air. The apparatus may include, and the methods may involve, a fixture. The fixture may include a germicidal light source. The fixture may include a fan. The fan may circulate air through a volume into which the germicidal light source propagates germicidal light. The light source may be configured to emit, upward from a horizontal plane, a beam that, absent reflection off an environmental object, does not cross the horizontal plane. The apparatus may include a shield that prevents light from the light source from crossing the horizontal plane. The sensor may face upward from the horizontal plane. The sensor may face downward from the horizontal plane.
US11400176B2 Automatic disinfecting machine for disinfecting the skin, and method
The invention relates to a method and an automatic disinfection machine for the controlled disinfection of the skin of a patient comprising a treatment chamber for accommodating the body part with the skin to be disinfected; an electrically controllable disinfecting device for disinfecting the skin, a recording device for recording the disinfection of the skin in the form of disinfection data, a data processing control device for controlling the disinfecting device and the recording device. The control device is thereby designed to effect the disinfection of the skin by controlling the disinfecting device, record the disinfection of a skin section of the skin in the form of disinfection data by controlling the recording device.
US11400175B2 Apparatus and method to measure concentration of disinfectant in medical device reprocessing system
A medical instrument processor includes an enclosure, a liquid distribution system, and a disinfectant concentration measuring subsystem. The enclosure is configured to hold a medical instrument. The liquid distribution system is configured to deliver a disinfection solution to a medical instrument within the enclosure. The liquid distribution system has a liquid outlet. The disinfectant concentration measuring subsystem includes a first mixing chamber in fluid communication with the liquid outlet, a pump that is configured to simultaneously pump the disinfection solution and the reagent solution into the first mixing chamber, and a concentration analysis assembly that is operable to determine a concentration of disinfectant in a sample solution that is output from the first mixing chamber. The reservoir is in fluid communication with the first mixing chamber.
US11400169B2 Long poly(A) plasmids and methods for introduction of long poly(A) sequences into the plasmid
Disclosed herein are polynucleotides having a plurality of thymine nucleotides and an endonuclease recognition site inserted therein, methods of engineering the polynucleotides having a plurality of thymine nucleotides and an endonuclease recognition site inserted therein, and methods of enhancing transcription, translation, and increasing stability of a polynucleotide.
US11400168B2 Methods and systems for noninvasive control of brain cells and related vectors and compositions
Provided herein are methods, systems, and related vectors and compositions allowing for noninvasive control of neural circuits. In particular, the methods and systems herein described utilize acoustically targeted chemogenetics to achieve a noninvasive neuromodulation in specifically selected cell-types among spatially selected brain regions.
US11400165B2 Composition and method for modifying polypeptides
The present disclosure provides methods for site-selectively crosslinking payloads to antibodies and other proteins. This can be accomplished using traceless affinity labels designed to label target proteins with bio-orthogonally reactive entities (ORE) using the compositions and methods described herein.
US11400162B2 Processes for the formulation of pneumococcal polysaccharides for conjugation to a carrier protein
The present invention provides a number of process improvements related to the conjugation of capsular polysaccharides from Streptococcus pneumoniae to a carrier protein. These process are serotype specific and include acid hydrolysis, addition of sodium chloride to the reductive amination reaction, and addition of sucrose to dissolve polysaccharides. Polysaccharide-protein conjugates prepared using the processes of the invention can be included in multivalent pneumococcal conjugate vaccines.
US11400159B2 Pharmaceutical compositions and related methods of delivery
The pharmaceutical compositions described herein include a suspension which comprises an admixture in solid form of a therapeutically effective amount of a therapeutic agent and at least one salt of a medium chain fatty acid and a hydrophobic medium, e.g. castor oil or glyceryl tricaprylate or a mixture thereof. The pharmaceutical compositions described herein contain medium chain fatty acid salts and are substantially free of alcohols. The pharmaceutical compositions may be encapsulated in a capsule. Methods of treating or preventing diseases by administering such compositions to affected subjects are also disclosed.
US11400158B2 Biodegradable lipids for the delivery of active agents
The present invention relates to a cationic lipid having one or more biodegradable groups located in a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.
US11400154B2 Method of treating a localized fibrotic disorder using an IL-33 antagonist
The subject invention provides a method of treating a patient suffering from a localized fibrotic condition which comprises administering to the patient an amount of an IL-33 antagonist effective to treat the patient. The subject invention also provides a method of treating a patient suffering from a localized fibrotic condition which comprises administering to the patient an amount of a TNF receptor 2 (TNFR2) antagonist effective to treat the patient.
US11400152B2 Compositions and methods for enhancing innate immunity in a subject for treatment of infections and cancer and other acute and chronic conditions of the eye
Embodiments of the present invention generally relate to novel immunostimulatory compositions of use to stimulate non-specific immune responses in a subject. In certain embodiments, immunogenic compositions disclosed herein can be directed to use in the eye of a subject. In some embodiments, the immunogenic compositions disclosed herein enhance non-specific immune responses in the eye of a subject to treat or reduce the risk of onset of an eye condition. In other embodiments, compositions disclosed herein can be used to treat eye infections due to a microorganism, tumors of the eye, as well as, chronic wounds of the eye.
US11400150B2 Construction of West Nile virus and dengue virus chimeras for use in a live virus vaccine to prevent disease caused by West Nile virus
The present invention relates to attenuated, immunogenic West Nile virus chimeras built on a dengue virus backbone for the production of immunogenic, live, attenuated West Nile virus vaccines,
US11400148B2 Surface exposed Haemophilus influenzae protein (protein E; pE)
The present invention relates to a surface exposed protein (protein E; pE), a virulence factor, which can be detected in Haemophilus influenzae, having an amino acid sequence as described in SEQ ID NO 1, an immunogenic fragment of said surface exposed protein, and a recombinant immunogenic protein (pE(A)) or truncated variants thereof based on said surface exposed protein. Nucleic acid sequences, vaccines, plasmids and phages, non human hosts, recombinant nucleic acid sequences, fusion proteins and fusion products are also described. A method of producing the said protein or truncated fragments thereof recombinantly is also disclosed.
US11400144B2 Complete genome sequence of the methanogen Methanobrevibacter ruminantium
The present invention includes the complete genome sequence for the methanogen, Methanobrevibacter ruminan-tium, including polynucleotides which encode M. ruminantium polypeptides or peptides, as well as polynucleotides from non-coding regions. Also included are the encoded M. ruminantium polypeptides and peptides, and antibodies directed to these peptides or polypeptides, in addition to expression vectors and host cells for producing these peptides, polypeptides, polynucleotides, and antibodies. The invention further includes methods and compositions for detecting, targeting, and inhibiting microbial cells, especially methanogen cells such as M. ruminantium cells, using one or more of the disclosed peptides, polypeptides, polynucleotides, antibodies, expression vectors, and host cells.
US11400142B2 Treatment of diabetic nerve injury comprising administering plasminogen
The present invention relates to the use of plasminogen in the prevention and/or treatment of diabetic neuropathic pain and neurohypersensitivity, and in the repair of nerve tissue injury. Therefore, plasminogen may become a new strategy for preventing and treating diabetic neuropathic pain.
US11400138B2 Method for improving skin condition with bioactive compound
A method for improving a skin condition of a subject in need thereof includes administering to the subject a composition including a bioactive compound. The bioactive compound is a peptide, and includes at least one amino acid sequence as set forth in SEQ ID NO: 1 to SEQ ID NO: 11. Each of the amino acid sequence is a peptide of fish skin.
US11400134B2 Modulating gamma-c-cytokine activity
Embodiments relate to peptide antagonists of γc-family cytokines, which is associated with important human diseases, such as leukemia, autoimmune diseases, collagen diseases, diabetes mellitus, skin diseases, degenerative neuronal diseases and graft-versus-host disease (GvHD). Thus, inhibitors of γc-cytokine activity are valuable therapeutic and cosmetic agents as well as research tools. Traditional approaches to inhibiting yc-cytokine activity involve raising neutralizing antibodies against each individual γc-cytokine family member/′ receptor subunit. However, success has been limited and often multiple γc-cytokine family members co-operate to cause the disease state. Combinatorial use of neutralizing antibodies raised against each factor is impractical and poses an increased risk of adverse immune reactions. The present embodiments overcome these shortcomings by utilizing peptide antagonists based on the consensus γc-subunit binding site to inhibit γc-cytokine activity. Such approach allows for flexibility in antagonist design. In several embodiments, peptides exhibit Simul-Block activity, inhibiting the activity of multiple γc-cytokine family members.
US11400132B2 Ophthalmic compositions comprising ciclosporin
The present invention relates to compositions in the form of a clear solution comprising ciclosporin with low residual water content and 1-perfluorobutyl-pentane. The compositions may be used for topical administration to the eye.
US11400131B2 Multi-peptide composition
The invention relates to a specific peptide combination. The peptide combination may be present in a pharmaceutically acceptable composition. The peptide combination can be used in the therapy or prevention of Type 1 Diabetes (TID). The invention also relates to a method of diagnosing or determining treatment efficacy, the method utilising the specific peptide combination.
US11400130B2 Inhibitors for proliferating cell nuclear antigen and uses
The present invention relates to series of compounds as an inhibitor targeting Proliferating Cell Nuclear Antigen (PCNA). Pharmaceutical compositions of those compounds and methods of using them in the treatment of cancer are within the scope of this disclosure.
US11400129B2 Increase in the content of essential fatty acids in eggs via nutritional supplementation of animals using a very low dose of a flavonoid-rich grape extract
Method for modifying the essential fatty acid profile of eggs through low-dose nutritional supplementation based on plant extract rich in flavonoids in the plant extract.The present invention relates to a method for supplementing animals that produce eggs that are intended for consumption and/or reproduction using a very low dose of plant extract so as to naturally modulate the profile of essential fatty acid in the eggs produced.Said method consists of a step of supplementing the complete feed and/or the drinking water of the animals using a very low dose of the plant extract and makes it possible to significantly increase the proportion of at least one polyunsaturated fatty acid of the omega-3 family, particularly alpha-linolenic acid (ALA) and/or docosahexaenoic acid (DHA), in the eggs produced by these animals.The present invention is particularly intended for the agro-feed industry, including the animal nutrition industry, in order to obtain eggs for consumption that are enriched with polyunsaturated fatty acids and/or to improve the quality of eggs intended for reproduction of the species, whether terrestrial and/or aquatic.
US11400128B2 Soybean seed extract, method for producing the same and uses thereof
The invention relates to a soybean seed extract, method for producing the same and uses of the extract of soybean seeds in promoting wound healing, promoting neuron cell proliferation and/or treating brain diseases and/or neurodegenerative diseases, treating breast cancer, reducing side effects of interfering with DNA and/or RNA replication drugs and/or enhancing pharmaceutical effects of interfering with DNA and/or RNA replication drugs.
US11400127B2 Method for processing ginseng with ultra-high pressure
The present invention relates to a method for processing ginseng at an ultra high pressure, and more particularly, to a method for processing ginseng that is capable of processing the ginseng, which is immersed and packed, at an ultra high pressure. The method for processing ginseng includes the steps of: preparing washed ginseng; liquid-packaging the ginseng into a pouch; and treating the liquid-packaged ginseng with ultra-high pressure at a pressure of 550 to 600 MPa for 30 seconds to 2 minutes.
US11400126B2 Compositions comprising Dead Sea extract and an extract of Apple of Sodom and uses thereof
Provided are compositions including at least one Dead Sea extract and at least one extract of the Apple of Sodom (Calotropis procera). Further provided are formulations including the compositions and their uses.
US11400120B2 Composition comprising collagen and honey
A composition comprising collagen and honey can be produced by addition of an aqueous solution of honey to an aqueous suspension of collagen. The composition is for use in medicine and particularly for use in the treatment of a wound. A method for treatment of a wound comprises administering the composition topically to the skin of a patient.
US11400119B2 Method of transporting mesenchymal stem cells by means of a transporting solution and a method of administering stem cells to wounds
The present invention relates to a method of transporting a stem cell population, the method comprising transporting the stem cell population contacted with a liquid carrier. In addition, the present invention concerns a method of treating a subject having a disease, the method comprising topically administering a defined mesenchymal stem cell population to the subject, wherein the mesenchymal stem cell population is administered within about 96 hours from the time point the mesenchymal stem cell population has been harvested. Also concerned is a unit dosage comprising about 20 million cells, of about 15 million cells, of about 10 million cells, of about 5 million cells, of about 4 million cells, of about 3 million cells, of about 2 million cells, of about 1 million cells, of about 0.5 million cells, of about 0.25 million cells or of less than 0.25 million cells of a defined mesenchymal stem cell population.
US11400115B2 Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy
The present disclosure relates in some aspects to methods, cells, and compositions for preparing cells and compositions for genetic engineering and cell therapy. Provided in some embodiments are streamlined cell preparation methods, e.g., for isolation, processing, incubation, and genetic engineering of cells and populations of cells. Also provided are cells and compositions produced by the methods and methods of their use. The cells can include immune cells, such as T cells, and generally include a plurality of isolated T cell populations or types. In some aspects, the methods are capable of preparing of a plurality of different cell populations for adoptive therapy using fewer steps and/or resources and/or reduced handling compared with other methods.
US11400112B2 Combination therapy for treatment of leukemia
The present invention relates to the treatment of leukemia, (e.g. acute myeloid leukemia, AML) using a triple combination of: arsenic trioxide; iron; and an artemisinin, such as artesunate.
US11400110B2 Altering microbial populations and modifying microbiota
The invention relates to methods, uses, systems, arrays, engineered nucleotide sequences and vectors for inhibiting bacterial population growth or for altering the relative ratio of sub-populations of first and second bacteria in a mixed population of bacteria. The invention is particularly useful, for example, for treatment of microbes such as for environmental, medical, food and beverage use. The invention relates inter alia to methods of controlling microbiologically influenced corrosion (MIC) or biofouling of a substrate or fluid in an industrial or domestic system.
US11400109B2 Subcutaneous delivery of messenger RNA
The present invention provides, among other things, methods of formulating nucleic acid-containing nanoparticles with an enzyme to afford efficient delivery of payload to a cell or tissue of interest via subcutaneous administration. In some embodiments, the present invention provides a process in which mRNA-loaded lipid nanoparticles are co-mixed with various amounts of hyaluronidase and administered via subcutaneous administration. The resulting payload can be efficiently delivered to the liver and other organs or tissues of a treated subject.
US11400104B2 Skeletal removal of bisphosphonates
Disclosed herein are methods and compositions for removing or displacing bisphosphonates in skeletal tissue.
US11400099B2 Drug-induced epigenetic remodeling to prevent fibrosis
A therapeutic treatment for preventing or reducing the formation of fibrosis comprising administering to a patient a UTX or JMJD3 inhibitor that are effective in preventing or reducing fibrosis in situations wherein access to an injury or dysmorphogenetic tissues before the fibrotic process becomes established in the tissues.
US11400098B2 Method of treating microbial infections
The disclosure provides for novel antimicrobial agents, methods of making, and methods of use thereof.
US11400096B2 Small molecules for the treatment of autoimmune disorders
Certain embodiments are directed to methods of treating autoimmune disorders by administering P2 purnergic receptor antagonist and/or adenosine receptor antagonists. The P2 purnergic receptor antagonist being chemical analogs of adenosine receptor antagonist 8-Ethoxy-9-ethyl-9H-purin-6-amine. The adenosine receptor antagonists being chemical analogs of the non-hydrolysable ATP analog adenosine 5′[γ-thio]triphosphate (ATPγS). Certain embodiments are directed to the use of the chemical analogs to modulate IL-17 activity.
US11400095B2 Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders
The invention provides substituted imidazo[1,5-a]pyrimidines and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,5-a]pyrimidine compounds described herein include substituted 2,4-dimethyl-N-phenylimidazo[1,5-a]pyrimidine-8-carboxamide compounds and variants thereof.
US11400092B2 Methods of treating myeloproliferative disorders
The present disclosure provides methods of mitigating thiamine deficiency.
US11400089B2 Multikinase inhibitors and uses in reproductive and digestive tract fibrosis
A method for preventing and/or treating fibrosis associated with a reproductive tract or digestive tract disease or disorder includes administering an effective amount of a multikinase inhibitor to an animal or human in need thereof. The multikinase inhibitor comprises axitinib, nintedanib, sunitinib, lenvatinib, regorafenib, ponatinib, pazopanib, riociguat, or a salt thereof. The reproductive tract or digestive tract disease or disorder comprises uterine fibroids or primary sclerosing cholangitis, including Intra uterine surgery, intra uterine synechiae, Asherman's syndrome, biliary duct fibrosis, biliary duct sclerosis, and primary biliary cirrhosis.
US11400088B2 Uses of compound in preparation of drugs for treating brain glioma
The present invention provides uses of a compound represented by formula A in the preparation of drugs for treating brain glioma and particularly glioblastoma. Particularly provided are uses of the compound represented by formula A in the preparation of drugs for treating expression of specific fusion protein. By means of the technical solution of the present invention, typing of brain glioblastoma can be implemented, a drug administration can be carried out for a specific patient group, and precise treatment can be implemented.
US11400083B2 CXCR4 antagonists with amino acid skeleton, preparation therefor and biomedical use thereof
The present invention provides a compound represented by formula (I), or a pharmaceutically acceptable salt or prodrug thereof.
US11400082B2 Methods of treating elevated plasma cholesterol
The present invention relates to compounds of Formula I, pharmaceutically acceptable salts, solvates or formulations thereof. Compounds of Formula I increase significantly low density lipoprotein receptor and are useful for preventing and treating of elevated cholesterol.
US11400081B2 Compounds
Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein R1, R2, R3, R4, R5, R6, R8, R9, X, X1, X2, X3, L1 and n are as defined herein. The compounds are inhibitors of adrenomedullin receptor subtype 2 (AM2). Also disclosed are the compounds for use in the treatment of diseases modulated AM2, including proliferative diseases such as cancer; pharmaceutical compositions comprising the compounds; methods for preparing the compounds; and intermediates useful in the preparation of the compounds.
US11400076B2 Cancer stem cell inhibitor
The object of the present invention is to provide a novel pharmaceutical for suppressing cancer stem cells. In the present invention, a mitochondria inhibitor comprising a 2-nitroimidazole derivative is applied to the cancer stem cell as an active ingredient.
US11400075B2 (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl phenylcarbamate and methods of treating or preventing neurodegeneration
The invention includes an amount of (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indol-5-yl phenylcarbamate for administering to a subject and also a method of preventing or treating neurotoxicity or neurodegenerative processes in a subject in need thereof using the amount thereof.
US11400071B2 Hest G-18-0 and benzoyl peroxide compositions and methods for using the same
The compositions of the various embodiments include benzoyl peroxide and Hest G-18-0. The methods of this invention include treating acne, increasing the solubility of benzoyl peroxide, and treating the skin. Embodiments are also directed to a dual chamber package comprising a chamber for benzoyl peroxide and a chamber for Hest G-18-0.
US11400070B2 Methods of treating retinal diseases
A method of treating or inhibiting degeneration of a retina of a subject in need thereof comprising administering an effective amount of a compound of metipranolol, or a metabolite thereof, to an organ, a tissue, or the subject, wherein the degeneration of the retina is caused by an ocular disease. In some embodiments, the compound, or a metabolite thereof, is administered topically, orally, or parenterally. In some embodiments, a drug delivery vehicle comprising a dosage of the compound, or the metabolite of, is delivered parenterally via intravitreal injection. In further embodiments, the dosage may range from 0.5 μg/day-15 μg/day.
US11400067B2 Pharmaceutical compositions and uses directed to lysosomal storage disorders
The present disclosure provides for treating lysosomal storage disorders (LSDs) comprising administering acetyl-leucine or a pharmaceutically acceptable salt thereof.
US11400062B2 Compositions comprising enzyme-cleavable amphetamine prodrugs and inhibitors thereof
Pharmaceutical compositions and their methods of use are provided, where the pharmaceutical compositions comprise an amphetamine prodrug that provides enzymatically-controlled release of amphetamine or an amphetamine analog. The composition can further comprise an enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of amphetamine or the amphetamine analog from the amphetamine prodrug so as to attenuate enzymatic cleavage of the amphetamine prodrug.
US11400053B2 Patch containing nonylic acid vanillylamide
The present invention provides a patch comprising a backing layer and an adhesive agent layer, wherein the adhesive agent layer is non-aqueous, the adhesive agent layer contains nonylic acid vanillylamide and aluminum hydroxide, a content of nonylic acid vanillylamide in the adhesive agent layer is 0.01 to 0.025% by mass based on a total mass of the adhesive agent layer, a content of aluminum hydroxide in the adhesive agent layer is 0.55 to 1.5% by mass based on the total mass of the adhesive agent layer, and a mass ratio of the content of nonylic acid vanillylamide to the content of aluminum hydroxide ((content of nonylic acid vanillylamide):(content of aluminum hydroxide)) in the adhesive agent layer is 1:27 to 1:150.
US11400051B2 Method for preserving biopharmaceuticals
The disclosure concerns methods for executing PBV protocols to preserve biopharmaceuticals using a conventional lyophilizer. Also described are steps for maintaining isolation of a biopharmaceuticals for achieving aseptic drying using the conventional lyophilizer. As a collateral benefit, the invention provides good manufacturing practice (GMP) compliant methods for achieving aseptic drying of biopharmaceutical compositions using a conventional lyophilizer disposed outside of a clean-room area. Finally, methods and formulations str disclosed for preserving biopharmaceuticals suitable for mucosal or transdermal delivery to a patient.
US11400049B2 Pegylated liposomal formulations of apelin for treatment of cardiovascular-related diseases
The disclosure relates generally to compositions comprising pegylated liposomal formulations of apelin for the treatment of cardiovascular-related diseases.
US11400047B2 Lozenge comprising micronized benzocaine and polyethylene glycol
The invention relates to a lozenge comprising micronized benzocaine, at least one dissolution enhancer and one or more excipients as well as the use of the lozenge for the treatment of sore throat.
US11400044B2 Thermoresponsive polymers and uses thereof
Compositions, methods, and kits for treating dry eye and related diseases are provided. In one aspect, the present disclosure relates to administering thermoresponsive polymeric compositions to the tear duct of the subject. Administering a thermoresponsive polymeric composition to the tear duct of the subject may be useful in treating dry eye and related conditions.
US11400042B2 Process for treating keratin fibres, comprising the application of a composition comprising urea or a derivative thereof, a polyol and an amino silicone
The present invention relates to a process for treating keratin fibres, in particular human keratin fibres such as the hair, comprising: 1) a step of applying to the keratin fibres a composition comprising: a) one or more compounds chosen from urea and/or urea derivatives, b) one or more polyols, c) one or more amino silicones, 2) a step of heat treatment of the keratin fibres, the heat treatment step 2) preferably being after step 1). The present invention also relates to a composition that may be used in the process according to the invention.
US11400039B2 Changing eye color by gene transduction
A person's iris color can lighten, such as from brown to lighter brown, green, hazel, or blue, by introducing a melanocyte-killing agent through the cornea of the person's eye and contacting the anterior surface of the iris with the agent at a dose sufficient to kill melanocytes in the iris stroma.
US11400035B2 Preservative mixture
Suggested is a preservative mixture with improved solubility comprising or consisting of (a) 4-isopropyl-3-methylphenol; (b) at least one hydrophilic solvent having a log Po/w of 1.2 or below; and (c) at least one lipophilic solvent having a log Po/w of above 1.2.
US11400033B2 Water-in-oil type emulsification cosmetic
The purpose of the present invention is to provide a water-in-oil emulsified solid cosmetic having a relatively high internal-aqueous-phase proportion (about 40% or higher), the cosmetic being a makeup which has an excellent concealing effect and gives a natural finish and which is stable and has satisfactory applicability. The present invention relates to a solid cosmetic in water-in-oil emulsified type characterized by comprising (A) at least one fatty acid glyceryl ester selected from the group consisting of glyceryl isostearate, poly(2-glyceryl) diisostearate, and glyceryl oleate, (B) an aqueous component, (C) an oily component, and (D) a powdery component, the oily component (C) comprising a solid oil (C1) and an oil-soluble film former (C2) and the powdery component (D) comprising titanium dioxide (D1) having a primary-particle diameter of 0.05-0.5 μm in an amount of 10 mass % or more relative to the whole cosmetic preparation and further containing a pearl pigment (D2).
US11400032B2 Tooth whitening oral care product with core shell silica particles
The present invention provides a tooth whitening oral care composition comprising: (i) a dye having a blue to blue-violet color with a hue angle in the CIELAB system ranging from 200 to 320 degrees; (ii) core shell silica particles, wherein each core shell silica particle comprises a silica core, and a surface of the silica core is etched with metal silicate; (iii) an orally acceptable carrier vehicle comprising a non-aqueous solvent; and wherein the composition comprises water in an amount of from 3 weight % to 30 weight %.
US11400031B2 Dental cement compositions and methods of use
Provided herein are dental compositions and methods for use in dental cementation applications.
US11400030B2 Two-paste dental curable composition
The present invention provides a two-paste dental curable composition achieving clinically acceptable bond durability to dental adherends including dental glass ceramic restorations (particularly lithium disilicate-containing glass ceramic restorations) without using conventionally used primers. The present invention relates to a two-paste dental curable composition comprising: a first agent comprising a polymerizable monomer (a) having an acid group, a polymerizable monomer (b) having no acid group, a polymerization initiator (c), and a filler (d); and a second agent comprising a polymerizable monomer (b) having no acid group, at least one filler (e) selected from the group consisting of a basic glass filler and alumina, a polymerization accelerator (f), and a silane coupling agent (g) represented by the following general formula [I]: (The definitions of the symbols are omitted.)
US11400028B2 Dental milling blank for the production of permanent indirect restorations and computer-aided process for producing the permanent indirect restorations
A dental milling blank for the production of permanent indirect restorations in the CAD/CAM process, characterized in that it has a water sorption WSP of less than/equal to 18 μg/mm3, measured according to ISO 4049 and an E modulus E greater than/equal to 13 GPa, measured according to the ADA specification No. 27 and a quotient Q of WSP/E of less than 1.35 μg/(GPa×mm3) and consists of the polymerization product of a radically curable dental composition, which comprises a) inorganic fillers, wherein the total mass of the inorganic fillers is at least 83 wt. %, based on the total mass of the composition, b) radically polymerizable monomers, c) one or more initiators for radically curing.