Document Document Title
US11359029B2 FC engineered anti-TNFR superfamily member antibodies having enhanced agonistic activity and methods of using them
The present invention relates to engineered anti-TNFR superfamily member antibodies having enhanced agonistic activity and methods of using them.
US11359022B2 CD80 variant immunomodulatory proteins and uses thereof
Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.
US11359019B2 Antibodies to LILRB2
Provided herein are various embodiments relating to antibodies that bind LILRB2. Anti-LILRB2 antibodies can be used in methods to treat disease, for example, cancer.
US11359018B2 Anti-PD-1 antibodies and compositions
This invention relates to anti-PD-1 antibodies and methods of using them in treating diseases and conditions related to PD-lactivity, e.g., cancer.
US11359017B2 Method of altering an antibody-related adverse event based on SCD163 and/or CXCL5 levels
The present invention provides a novel method of obtaining data for predicting the onset of an adverse event due to administration of at least one antibody drug selected from an anti-PD-1 antibody, an anti-PD-L1 antibody, an anti-CTLA4 antibody, and an antigen-binding fragment thereof, or a novel method of predicting the onset of the adverse event. More specifically, the present invention provides a method of obtaining data for predicting the onset of an adverse event or a method of predicting the onset of the adverse event, comprising measuring a level of at least one marker selected from sCD163 and CXCL5 in a biological sample collected from a subject administered the antibody drug.
US11359015B2 Humanized or chimeric CD3 antibodies
The present invention relates to humanized or chimeric antibodies binding CD3. It furthermore relates to bispecific antibodies, compositions, pharmaceutical compositions, use of said antibodies in the treatment of a disease, and method of treatment.
US11359012B1 Specific chimeric antigen receptor cells targeting human CLDN18A2, preparation method and application thereof
A chimeric antigen receptor (CAR) cell specifically targeting human Claudin18.2 (CLDN18A2), a preparation method and an application thereof are provided. The extracellular binding region of the CAR includes a protein specifically recognizing CLDN18A2 that has any one of the amino acid sequences as shown in SEQ ID NOS: 2-5 or any one of the amino acid sequences of the variants having 70%-99% identity with the amino acid sequences shown by the SEQ ID NOS: 2-5. The immune effector cell modified by the CAR can be used to treat tumors.
US11359010B2 Humanized anti-S100A9 antibody and uses thereof
It is provided an inhibitor of Toll-like Receptor 2 (TLR2) that specifically blocks an interaction between S1009A and Toll-like Receptor 2 (TLR2), and more particularly a humanized antibody against S100A9 protein for inhibiting and treating inflammatory conditions in a human patient. Particularly, this humanized antibody is specific for blocking the interaction between the S100A9 protein and the TLR-2 receptor.
US11359004B2 Succinimide-activated nitroxyl compounds and methods for the use thereof for nitroxylation of proteins
The present invention relates to succinimide-activated nitroxyl compounds and methods for the synthesis of such compounds. The present invention also relates to the use of succinimide-activated nitroxyl compounds to prepare nitroxylated proteins, for example nitroxylated heme proteins (e.g., nitroxylated hemoglobin and nitroxylated myoglobin). The nitroxylated proteins are optionally also conjugated to a polyalkylene oxide (PAO), for example to a polyethylene glycol (PEG). Polynitroxylated heme proteins are useful as oxygen therapeutic agents (OTAs). The invention further relates to pharmaceutical compositions of the nitroxylated proteins and methods for the use of nitroxylated proteins in the treatment of various conditions.
US11359000B2 Interleukin-2/Interleukin-2 receptor alpha fusion proteins and methods of use
Disclosed herein are fusion proteins comprising: (a) a first polypeptide comprising Interleukin-2 (IL2); and (b) a second polypeptide, fused in frame to the first polypeptide, wherein the second polypeptide comprises an extracellular domain of Interleukin-2 Receptor alpha (IL2Rα), wherein IL2 or IL2Rα comprises at least one fewer glycosylation site compared to native IL2 or native IL2Rα. Methods of production and methods of therapeutic use of the fusion proteins are also disclosed.
US11358998B2 Cretion-competent muteins of the human IL-27 alpha-subunit
The present invention refers to a secretion-competent mutein of the α-subunit of human Interleukin 27 and to a human heterodimeric Interleukin 27. The present invention further refers to a nucleic acid molecule comprising a nucleotide sequence encoding a secretion-competent mutein of the α-subunit of human Interleukin 27 or the human heterodimeric Interleukin 27, to a host cell containing a nucleic acid molecule comprising a nucleotide sequence encoding a secretion-competent mutein of the α-subunit of human Interleukin 27 or of the human heterodimeric Interleukin 27. The invention also refers to an immune modulator comprising a secretion-competent mutein of the α-subunit of human Interleukin 27 or of the human heterodimeric Interleukin 27, to the respective use thereof as well as to a method of producing said secretion-competent muteins and to a secretion-incompetent mutein of the α-subunit of mouse Interleukin 27 and a secretion-competent mutein of the β-subunit of mouse Interleukin 27.
US11358997B2 Fusokines involving cytokines with strongly reduced receptor binding affinities
The present invention relates to a fusion protein comprising at least two cytokines, of which at least one is a modified cytokine with a strongly reduced binding affinity to its receptor, or to one of its receptors. Preferably, both cytokines are connected by a linker, preferably a GGS linker. The invention relates further to said fusion protein for use in treatment of diseases.
US11358996B2 Method for improving resistance to breakage and eggshell strength
Described herein are FGF-23 epitope peptides, methods of producing antibodies in laying hens by injecting the peptides, and methods of improving resistance to eggshell breakage and/or increasing eggshell strength by administering an FGF-23 epitope peptide to a laying hen.
US11358990B2 Recombinant polypeptides containing at least one immunogenic fragment and antibody fc region and uses thereof
Provided is a recombinant polypeptide containing at least one immunogenic fragment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) spike glycoprotein, and pharmaceutical compositions containing the same.
US11358989B2 Apratyramide therapeutic agents and methods of treatment
The invention is directed towards Apratyramide linear depsipeptide compounds, pharmaceutical compositions thereof, and methods of affecting wound healing, and methods of affecting the biological processes involved in wound healing (e.g., inflammation, cell proliferation, tissue granulation, remodeling of scar tissue, etc.).
US11358987B2 Albicidin derivatives, their use and synthesis
It is provided a chemical compound according to general formula (1)
US11358986B2 IL-2RBETA binding compounds
IL-2Rβ ligands and IL-2Rγc ligands and compounds comprising the ligands are disclosed. The ligands and compounds such as heterodimers and fusion proteins comprising the IL-2Rβ ligands and/or the IL-2Rγc ligands can be IL-2 receptor agonists.
US11358984B2 Use of Raman spectroscopy in downstream purification
In situ Raman spectroscopy methods and systems for characterizing or quantifying a protein purification intermediate and/or final concentrated pool during production or manufacture are provided. In one embodiment, in situ Raman spectroscopy is used to characterize or quantify protein purification intermediates critical quality attributes during downstream processing (i.e., after harvest of the protein purification intermediate). For example, the disclosed in situ Raman spectroscopy methods and systems can be used to characterize and quantify protein purification intermediates as the protein purification intermediates are purified, condensed, or otherwise formulated into the final drug product to be sold or administered.
US11358970B2 Artemisinin-derived trimers and tetramers and their use thereof
The present disclosure provides compositions comprising artemisinin-derived trimers and tetramers; methods of preparing these compositions; and methods for their use as medicaments.
US11358962B2 2-hetaryl imidazol[1,2-a]pyridine derivatives
The invention relates to small molecule imaging tools, specifically compounds of formula II and to pharmaceutically acceptable acid addition salts thereof, wherein R1-R6 have any of the values defined in the specification.
US11358959B2 Benzothiophene and benzothiazole compounds and methods of use thereof
Compounds having activity as inhibitors of G12C mutant KRAS protein are provided. The compounds have the following structure (I) or a pharmaceutically acceptable salt, stereoisomer or prodrug thereof, wherein B, Z, Ra, Rb, Rc, R1, L, L1 and E are as defined herein. Methods associated with preparation and use of such compounds, pharmaceutical compositions comprising such compounds and methods to modulate the activity of G12C mutant KRAS protein for treatment of disorders, such as cancer, are also provided.
US11358958B2 Inhibitors of cyclin-dependent kinases
Provided herein are inhibitors of cyclin-dependent kinases (CDKs), pharmaceutical compositions comprising said compounds, and methods for using said compounds for the treatment of diseases.
US11358952B2 Substituted 4-aminoisoindoline-1,3-dione compounds, compositions thereof, and methods of treatment therewith
Provided herein are 4-aminoisoindoline-1,3-dione compounds having the following structure: wherein R, Ring A, and n are as defined herein, compositions comprising an effective amount of a 4-aminoisoindoline-1,3-dione compound, and methods for treating or preventing disorders.
US11358949B2 Carbamate and urea compounds as multikinase inhibitors
The present disclosure describes carbamate and urea compounds as novel multikinase inhibitors and methods for preparing them. The pharmaceutical compositions comprising such multikinase inhibitors and methods of using them for treating cancer, infectious diseases, and other disorders associated with kinases are also described.
US11358947B2 Substituted 2-acylamino-cycloalkylthiophene-3-carboxylic acid arylamides as inhibitors of calcium-activated chloride channel TMEM16A
Provided herein are inhibitors of transmembrane protein 16A (TMEM 16A), a Ca2+-activated CI″ channel expressed widely in mammalian epithelia, as well as in vascular smooth muscle and some tumors and electrically excitable cells. TMEM16A inhibitors have potential utility for treatment or management of disorders of epithelial fluid and mucus secretion, hypertension, some cancers, pain, and other diseases.
US11358945B2 Method for preparing cyclopenta[c]chromium compound
The present invention discloses a method for preparing a cyclopenta[c]chromene compound. A cationic rare earth compound [Ln(CH)3CN)9]3+[(AlCl4)3]3−.CH3CN is used as a catalyst, and p-methyl thiophenol is used as an accelerator for a catalytic reaction of a chalcone compound so as to prepare a product; and Ln, contained in the catalyst, represents a positive trivalent rare earth metal ion and is selected from one of La, Nd, Sm, Gd and Yb. According to the method, the starting materials are easy to obtain, the reaction process is simple, the catalyst usage is low, the catalyst is universally applicable to various substituted 2-hydroxy chalcones, and the obtained cyclopenta[c]chromene compound has not been reported. The catalyst synthesis method is simple and easy to obtain, and the yield of the target product is high.
US11358944B2 Anxiolytic deuterated compound and medical use thereof
The present invention provides compounds as represented by structural formula (I). In formula (I), R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 are separately H or deuterium (D) independently. Moreover, at least one of R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, and R14 must be D. Also provided is use of any of the compounds or its pharmaceutical composition in the preparation of a drug for treating an anxiety.
US11358933B2 Compounds and methods for inhibiting CYP26 enzymes
Compounds that are inhibitors of retinoic acid inducible P450 (CYP26) enzymes. The compounds have retinoid activity, are resistant to CYP26-mediated catabolism, act as inhibitors of CYP26B1, and are used for treating diseases that are responsive to retinoids.
US11358930B2 Selective potassium channel agonists
Selective potassium channel agonists and methods of use thereof are disclosed. A compound, or a pharmaceutically acceptable salt thereof, having a formula I wherein R1 is H or optionally-substituted alkyl; R2 is optionally-substituted C1-C6 alkyl or optionally-substituted cyclopropyl; R3 and R4 are each independently H or optionally-substituted alkyl; R5 is H, optionally-substituted alkyl, acyl, or alkoxycarbonyl; R6 and R7 are each independently H, optionally-substituted alkyl, or R6 and R7 together form a carbocycle; R8 is substituted phenyl or optionally-substituted pyridinyl, provided that if R8 is substituted phenyl, then R2 is optionally-substituted cyclopropyl; and R9, R10 and R11 are each independently H, halo, or optionally-substituted alkyl.
US11358929B1 Biobased diisocyanates, and process for preparation of same
Biobased diisocyanates are derived from 3-petadecyl phenol, which is derived from Cardanol harvested from cashew nutshell liquid food waste. The biobased diisocyanates are of the formulas: wherein R is an alkyl chain C15H31 (n-pentadecyl); R1=CH3 or COCH3; and R2 is an alkylene of from about 1 to 18 carbon atoms.
US11358927B2 Method of producing N,N-disubstituted amide and catalyst for producing N,N-disubstituted amide
A method of producing an N,N-disubstituted amide of the present invention is a method of reacting a nitrile with an alcohol in the presence of a catalyst, wherein the nitrile is a compound represented by R1CN (R1 represents an alkyl group having 10 or less carbon atoms or an aryl group having 10 or less carbon atoms), wherein the alcohol is a compound represented by R2OH (R2 represents an alkyl group having 10 or less carbon atoms), wherein the catalyst is a metal salt represented by MXn (M represents a metal cation having an oxidation number of n, X represents a monovalent anion including a substituted sulfonyl group represented by —S(═O)2—R3 (R3 represents a hydrocarbon group having 10 or less carbon atoms or a group in which some or all of hydrogen atoms in the hydrocarbon group are substituted with fluorine atoms), and n represents an integer of 1 to 4), a substituent bonded to a carbon atom in a carbonyl group of the N,N-disubstituted amide is R1, and two substituents bonded to nitrogen atoms in an amide group are both R2.
US11358925B2 Recovery of propylene from reactor purge gas
A process of recovering propylene and N-butyraldehyde from a purge gas includes forming a first product stream including N-butyraldehyde by reacting propylene and a first synthesis gas in the presence of a first catalyst in a first reactor and a second reactor; withdrawing a mixed stream from the second reactor; separating a liquid stream and purge gas from the mixed stream and recycling the liquid stream to the second reactor; reacting the purge gas and a second synthesis gas in the presence of a second catalyst in a purge gas reactor to form a second product stream including N-butyraldehyde; withdrawing the second product stream including N-butyraldehyde from the purge gas reactor and combining the second product stream including N-butyraldehyde and the first product stream including N-butyraldehyde; and withdrawing a stream including N-butyraldehyde from the purge gas reactor and recovering N-butyraldehyde from the stream including N-butyraldehyde product stream.
US11358917B2 Sulfur injection in fluidization bed dehydrogenation on chromium catalyst for dehydrogenation process improvement and process scheme optimization
Systems and processes for producing isomerized alkenes are disclosed. The systems mainly include an isomerization unit, a dehydrogenation unit, and a MTBE synthesis unit. A hydrocarbon stream is fed into the isomerization unit to form iso-alkanes in a sulfur free hydrocarbon stream. The sulfur free hydrocarbon stream is heated and then combined with a sulfur-containing hydrocarbon stream comprising sulfur containing compounds to form a reactant feed stream to the dehydrogenation unit. The iso-alkanes is dehydrogenated to form iso-alkenes. The formed iso-alkenes comprising isobutylene can be used as a feed stock for the MTBE synthesis unit.
US11358915B2 Process for converting alkanes to olefins
A process and apparatus for converting an alkane to an olefin. In one embodiment, the process involves oxidative coupling of an alkane, e.g., methane, with an oxidant, such as air, to produce an olefin having twice the number of carbon atoms as the alkane, e.g., ethylene. In another embodiment, the process involves oxidative dehydrogenation of an alkane, e.g., ethane, with an oxidant to form an olefin having the same number of carbon atoms as the alkane, e.g., ethylene. The process involves passing a flow of the oxidant from a first flow passage through a porous medium; diffusing a flow of the alkane from a second flow passage into the porous medium; and contacting the reactant alkane and the oxidant in the presence of a catalyst within the porous medium to produce the olefin.
US11358913B2 Method for oligomerizing olefins
The present invention relates to a method for oligomerizing olefins including the steps of: carrying out an oligomerization reaction of olefins by injecting an oligomerization transition metal catalyst, a cocatalyst, an olefin monomer and a solvent into a reactor; and injecting, into the reaction product of the oligomerization reaction, a catalyst inactivator including a gaseous inorganic material that contains oxygen.
US11358907B2 Biological solids processing
A method of processing biological solids includes blending a sludge with calcium oxide and delivering the blended sludge and calcium oxide to a pressurized container; injecting, into the blended sludge and calcium oxide in the pressurized container, an additive capable of exothermic reactions with the calcium oxide; regulating pH in the pressurized container to produce class A biological solids from the sludge; and pumping the blended sludge, calcium oxide, and additive from the pressurized container to a reactor. A system used for this process include sources of calcium oxide and biological solids, an additive injector, and a pressurized reactor.
US11358893B2 Positive polymer fecal sludge treatment apparatus
A positive polymer fecal sludge treatment apparatus comprising a trash separator, one end of which is connected with a sludge inlet, and the other end of which is connected with a twin-rotor vacuum water pump. A high-pressure transparent tube is disposed and connected, by a knife valve, between the trash separator and the twin-rotor vacuum water pump. One end of the knife valve is connected with a first material box and a second material box. A first chemical box and a second chemical box are disposed under the first material box and the second material box, and each of the first material box and the second material box is connected with the first chemical box and the second chemical box. The first and second material boxes have a larger volume than a conventional one and thus can store more material and also can perform chemical stirring reaction directly.
US11358891B2 Treatment of aqueous systems
A method is described for selecting a treatment additive for aqueous systems, in which crystal habit modification properties are prioritized; for aqueously preparing a substantially poly-maleic additive through in-situ formation of maleic acid copolymer so that mono-carboxylic acids, non-ionic functional groups, and terminal hydroxyl groups are also formed during polymerization; and for applying such additives for treatment of aqueous systems. Treatment agents resulting from these processes are also described.
US11358889B2 Multi-zone process and apparatus for treating wastewater
Wastewater containing organic matter may be treated using a multi-zone apparatus. In a first zone, organic matter in the wastewater may, among other things, be converted to at least volatile fatty acids (VFAs) and, thereafter, a portion of the treated wastewater may flow to a second zone that may, among other things, convert the VFAs to methane.
US11358887B2 Treatment system for PMIDA wastewater
The invention provides a treatment system and a treatment method for PMIDA high-salinity wastewater. The treatment system includes a booster pump, a water inlet-outlet heat exchanger, a water inlet heater and an oxidation reactor, and the water inlet-outlet heat exchanger is provided with a wastewater inlet, a wastewater outlet, an oxidized water inlet, and an oxidized water outlet. An oxidized water from the oxidation reactor enters the water inlet-outlet heat exchanger through the oxidized water inlet, the oxidized water outlet is connected to an intermediate tank, the wastewater inlet is connected to the booster pump, and the wastewater outlet is connected to a wastewater heater. A micro-interface unit is disposed at the lower part in the oxidation reactor, for dispersing crushed gas into bubbles. A gas inlet is formed at a side wall of the oxidation reactor and is connected to the micro-interface unit through a pipeline.
US11358885B2 Method and device for treating acrolein reactor wastewater
A method for treating acrolein reactor wastewater, comprising the steps of: S1. mixing acrolein reactor wastewater and a carbonate aqueous solution to obtain a mixed solution, wherein the acrolein reactor wastewater has a pH value of less than 2 and contains 500 ppm to 3,000 ppm of acrolein, 50 ppm to 800 ppm of allyl alcohol, 40,000 ppm to 100,000 ppm of acrylic acid, 10,000 ppm to 30,000 ppm of formaldehyde, 3,000 ppm to 10,000 ppm of acetic acid and 3,000 ppm to 8,000 ppm of maleic acid; and the mixed solution has a pH value of 4 to 6, a COD concentration ranging from 7,500 ppm to 30,000 ppm, and a formaldehyde concentration ranging from 800 ppm to 4,000 ppm; S2. conveying the mixed solution obtained in step S1 to an anaerobic reactor (4) for biochemical treatment; and S3. conveying the solution treated in step S2 to an aerobic biochemical tank (5) for treatment; and reflowing at least one part of the solution treated in step S2 and/or S3 to step S2. Also provided is a device for treating acrolein reactor wastewater.
US11358884B2 Water treatment apparatus and water treatment method
A water treatment apparatus includes: a treatment tank, having therein a grounded electrode and a high-voltage electrode opposing the grounded electrode, for generating electric discharge between both the electrodes, and causing to-be-treated water to pass between the electrodes and contact with the electric discharge to perform water treatment, an ozone mixing portion for supplying ozone-containing gas in the treatment tank through a gas sending portion to the to-be-treated water supplied from outside, and a gas returning portion for sending gas in the ozone mixing portion to the treatment tank, are provided, and water treatment is performed by ozone in the ozone mixing portion, and water treatment is thereafter performed by the electric discharge in the treatment tank.
US11358883B2 System and method for using ultramicroporous carbon for the selective removal of nitrate with capacitive deionization
The present disclosure relates to a flow through electrode, capacitive deionization (FTE-CDI) system which is able to adsorb nitrates from water being treated using the system. The system makes use of a pair of electrodes arranged generally parallel to one another, with a water permeable dielectric sandwiched between the electrodes. The electrodes receive a direct current voltage from an electrical circuit. At least one of the electrodes is formed from a carbon material having a hierarchical pore size distribution which includes a first plurality of pores having a width of no more than about 1 nm, and a second plurality of micro-sized pores. The micron-sized pores enable a flow of water to be pushed through the electrodes while the first plurality of pores form adsorption sites for nitrate molecules carried in the water flowing through the electrodes.
US11358882B2 Water ionizer including stacked electrolyzer and flow switching device, with inlet being separate from outlet
A water ionizer includes a stacked electrolyzer and a flow switching device, with an inlet being separate from an outlet. Water entering an input regulator is distributed at a predetermined ratio before being supplied to an electrolyzer module to minimize acidic water to be discarded. Water supplied from the input regulator is directed to pass through the electrolyzer module in a crossing manner to delay flows of water to improve the efficiency of electrolysis. Electrolyzer cells are stacked on and fitted to each other to simplify an assembly process and improve convenience. Electrode plates of the electrolyzer module are fixedly fitted into a frame to facilitate an assembly process and improve a fabrication process. The input regulator and a flow switching output unit are connected via a connecting shaft to synchronize the operations thereof to obtain reliability.
US11358874B2 Sheet silicate lamellae with a high aspect ratio
The present invention relates to sheet silicate lamellae of a 2:1 sheet silicate with a high aspect ratio, to a method for producing these sheet silicate lamellae and to an aqueous dispersion which comprises the sheet silicate lamellae. The present invention further relates to the use of the sheet silicate lamellae of the invention for producing a composite material, and also to a corresponding composite material comprising or obtainable using the sheet silicate lamellae, more particularly for use as a diffusion barrier or as a flame retardant.
US11358870B2 Crystalline magnesium oxide carbon composites
Carbon dioxide can be converted into a higher energy product by contacting carbon dioxide with a polarized monocrystalline magnesium oxide producing at least in part carbon. Further a novel crystalline magnesium oxide carbon composite comprising crystalline magnesium oxide and crystalline carbon having graphene structure which are interwoven is provided.
US11358869B2 Methods and systems for microwave assisted production of graphitic materials
Systems and methods for plasma based synthesis of graphitic materials. The system includes a plasma forming zone configured to generate a plasma from radio-frequency radiation, an interface element configured to transmit the plasma from the plasma forming zone to a reaction zone, and the reaction zone configured to receive the plasma. The reaction zone is further configured to receive feedstock material comprising a carbon containing species, and convert the feedstock material to a product comprising the graphitic materials in presence of the plasma.
US11358864B2 Chalcogen-containing compound, its preparation method and thermoelectric element comprising the same
A chalcogen-containing compound of the following Chemical Formula 1 which exhibits excellent phase stability at a low temperature, particularly at a temperature corresponding to the driving temperature of a thermoelectric element, and also exhibits an excellent thermoelectric performance index through an increase in a power factor and a decrease in thermal conductivity, a method for preparing the same, and a thermoelectric element including the same: V1-xMxSn4Bi2Se7-yTey  [Chemical Formula 1] In the above Formula 1, V is a vacancy, M is an alkali metal, x is greater than 0 and less than 1, and y is greater than 0 and less than or equal to 1.
US11358863B2 Method and composition of humidity-controlled generation of chlorine dioxide in polymers and superabsorbent hydrogels
A composition and method for chlorine dioxide production through reaction-diffusion chemistry that facilitates the in situ generation of chlorine dioxide, wherein a dry solid composition of hydroxymethanesulfinic acid monosodium salt dihydrate (abbreviated HMS) and a chlorine dioxide precursor are activated via the addition or absorption of water to produce chlorine dioxide. The dry solid chemical composition comprises dry, safe, transportable reagents that integrate with polymeric materials such as packaging and superabsorbent and stimuli-responsive hydrogel polymers to combine with water to produce chlorine dioxide.
US11358860B2 Apparatus and method for dissipating heat with microelectromechanical system
In one or more embodiments, an apparatus generally comprises a microelectromechanical system (MEMS) module comprising a plurality of air movement cells and a power unit operable to control the plurality of air movement cells, and a housing configured for slidably receiving the MEMS module and positioning the MEMS module adjacent to a heat generating component of a network device. The MEMS module is operable to dissipate heat from the heat generating component and is configured for online installation and removal during operation of the heat generating component.
US11358855B2 Valve closure incorporating an over-pressure relief valve
The valve closure (e.g. an A-type closure) has a closure body (1) for attachment to a container, a gas inlet port (14), a liquid dispensing port (25), and a valve member (6) to sealably close the gas inlet and liquid dispensing ports. An over-pressure relief valve (40) is configured to release gas from within the container in the event that an internal pressure limit is exceeded, and a user-operable depressurising lever (50) is arranged to permit the over-pressure relief valve to be manually opened. The over-pressure relief valve (40) comprises a plunger (53) which is urged against a seat (52) by a spring (57), and the depressurising lever (50) incorporates an abutment (58) for the spring (57). The plunger (53) includes an arrowhead formation (59) by which the depressurising lever (50) engages the plunger to hold the valve open during manual operation. The depressurising lever (50) incorporates an integral hinge (62) which also forms a frangible connection so that the lever becomes detached from the closure body and permanently opens the over-pressure release valve when manually operated.
US11358854B2 Package
The invention relates to a package comprising a carton and a flexible bag to contain a flowable product, the bag having a dispensing outlet for dispensing the flowable product, the carton having an internal wall defining to one side of the wall a first cavity within the carton for locating the bag, the internal wall having an opening within which a body of the dispensing outlet is located whereby an outer end of the dispensing outlet lies within a second cavity defined between an opposite side of the internal wall and an adjacent external wall of the carton, the carton including a removable area leading into the second cavity to expose the dispensing outlet and provide access thereto.
US11358848B2 Multi-function levering and pivoting device for the toting of a personal water or beverage bottle
The present device is an improvement in the manner in which individuals are enabled to more swiftly and conveniently attach, detach, store, reposition, carry, tote, and ultimately access the contents of a commercially manufactured personally sized beverage container having a circumferential flange about its neck region, regardless of either the shape or the size of the containers neck. Being easily affixed and subsequently detached from clothing or accoutrements, this simple and inexpensive device enables the mobile user to enjoy an unencumbered hands-free toting experience which in turn further promotes responsible behavior in such activities as the disposal, the recycling, or reuse of the container. Further, the frame itself is configured to be potentially cast from either a recycled resin-based material, or it can also be just as efficiently cast, or die-cut from a non-floatable type of recyclable metal, which makes the end-use of this convenience device most environmentally friendly.
US11358846B1 Level compensator
A level compensator system may be configured to receive containers of different heights and position them at the same level. The level compensator system can include engagement platforms for engaging with the containers. The engagement platforms can move between an engagement configuration for engaging with the containers and a conveyance configuration for conveying of the containers relative to the level compensator.
US11358843B2 Retracting carriage attachment
A retractable pallet fork carriage assembly is provided that enhances the safe operation of a lift vehicle, such as a loader or telehandler. A carriage assembly is coupled to a fork tyne assembly through scissor links that expand and retract the tynes relative to the carriage assembly. When the scissor links are closed, the fork tynes extend through the carriage assembly to receive a payload (e.g., a pallet). When an operator wants to remove the payload, the fork tynes retract while the payload is supported against the carriage assembly. In this way, the load remains in one stationary position while pallet fork tynes are retracted under the payload to release the payload. Various sensors generate and/or send signals to limit the operation of the boom lift, boom, and/or retractable attachment when a distance or load is out of a threshold range.
US11358841B2 Shutdown buffer for a lifting device, in particular chain hoist, and lifting device herewith
A shut-down buffer for a lifting device, in particular a chain hoist, includes two opposing end surfaces and at least two mutually spaced web elements extending between the end surfaces. The shut-down buffer is defined by the end surfaces, between which a through-opening for passage of a load-bearing element of the lifting device extends through the shut-down buffer.
US11358838B2 System and method for controlling the lifting and handling of a load
Described is a system for connecting a lifting device to a load to be lifted. The system includes a first connector member and a second connector member. The first connector member includes at least one pin. The second connector member includes an indexer mechanism defining a track that includes at least one track opening. At least a portion of the second connector is receivable in at least a portion of the first connector. At least a portion of the at least one pin is receivable in the track via the at least one track opening. The first connector member is reversibly coupleable to the second connector member via the pin and the indexer mechanism in response to a first series of longitudinal movements of the first or second connector members.
US11358834B2 Elevator guide rail element
The elevator guide rail element comprises a guide rail element having a first jointing clamp attached to a lower end of the guide rail element and a second jointing clamp attached to an upper end of the guide rail element. The first and the second jointing clamp forms a plug-in joint between the first and the second jointing clamp and thereby between two consecutive guide rail elements when the first and the second jointing clamp are connected to each other.
US11358829B2 Filament winding apparatus
A filament winding apparatus winds, around a workpiece, a fiber bundle formed by bundling a plurality of fibers. The filament winding apparatus includes a widening roller that rotates while making contact with the fiber bundle that is being conveyed. The widening roller has, provided on the peripheral surface, a plurality of projecting ridges extending in the axial direction, the projecting ridges being arranged side by side in the circumferential direction. The projecting ridges make contact with the fiber bundle to thereby widen the fiber bundle.
US11358828B2 Unwinding of materials
There is provide a process for unwinding material from a spool (2) wherein the angle (Θ) of take off at the first contact point (4) for the unwind is always in the range 0±20°, and wherein the first contact point (4) for the unwind is no more than 600 mm from the axis (3) of rotation of the spool (2). There is also provided an apparatus for the unwinding of material from a spool (2) comprising an axis (3) upon which a spool (2) may be rotatably mounted and a static first contact point (4) for the unwound material positioned no more than 600 mm from the centre of the axis (3), wherein the angle (Θ) of take off at the first contact point (4) for the unwind is always in the range 0±20°.
US11358827B2 Postprocessing apparatus and image processing system
A postprocessing apparatus includes a horizontal alignment plate, a binder, a tray, and a shift actuator assembly. The horizontal alignment plate is positioned to align sheets in a sheet width direction. The binder binds sheets to form bound sheet bundles. The bound sheet bundles are stacked on the tray. The shift actuator assembly shifts the bound sheet bundles in the sheet width direction. A postprocessing controller controls the shift actuator assembly to shift the bound sheet bundles such that swollen portions of the bound sheet bundles are shifted inward of the horizontal alignment plate in the sheet width direction when the processed sheets are piled on the tray to the vicinity of the horizontal alignment plate.
US11358826B2 Method of grouping sheet units belonging to sheet groups, a grouping unit and a sheet handling system
A method of grouping sheet units, which belong together in sheet groups, a sheet stream comprising two superposed sheet units each by means of a grouping unit, a grouping unit for a sheet handling system, and a sheet handling system that allow a high processing speed and a high cycle efficiency of a sheet handling system are disclosed. A sheet unit can be held back in the grouping unit. Depending on whether the downstream subsequent sheet units transferred into the grouping unit belong to a sheet group, the held-back sheet unit can be released by itself and together with one or together with both downstream subsequent sheet units.
US11358824B2 High throughput double staple system and method
A finisher assembly of a multifunction peripheral includes a vertically oriented stapler and a paper transport motor. When the paper transport motor rotates in the forward direction, printed pages from the print engine of the multifunction peripheral are received via a paper chute and a feed assist roller urges the printed pages into a vertical paper accumulation cache basin. Rotation of the paper transport motor also opens a biasing plate allowing the pages to freely enter the cache basin. Once all of the pages of the print job are in the cache basin, the paper transport motor rotates in the reverse direction causing the biasing plate to bias the printed pages, in the cache basin, against a registration surface of the vertically oriented stapler unit. The pages of the print job are stapled together the stapled print job is moved to the paper tray for collection by a user.
US11358822B2 Pad of dispensable tape segments
A pad of dispensable adhesive tape segments is shown and described. The pad includes a protective envelope and a number of tape segments. The tape segments are arrayed such that detachable pull tabs for each are exposed for grasp. The envelope may include a strip folded over onto itself and adhered in place. The envelope is pulled open and may be adhered to an environmental surface. Tape segments have adhesive of weaker adherence than the adhesive of the envelope so that when pulled by a pull tab, each tape segment preferentially releases from the next, but the envelope maintains adherence to the environmental surface. Adhesive lined tabs initially holding the envelope closed may also be used for adherence to the environmental surface. Preferably used for medical tape, the envelope is waterproof to maintain sterility of tape segments.
US11358820B2 Media bin sensors
A printing apparatus includes a media bin and a sensor, directed toward the media bin, having a first emitter and a receiver. The printing apparatus further includes a second emitter to emit photons toward the optical sensor, and a controller. The controller determines presence of a print media on the media bin based on a count of photons received from a source other than the first emitter, including the second emitter.
US11358818B2 Control apparatus and feeding apparatus
The control apparatus includes an acquisition unit, an air volume setting unit, and an air blow control unit. The air volume setting unit sets a volume of air to be blown toward the plurality of sheets from a separation blower based on the information on the processing job acquired by the acquisition unit or by manipulation of a user. When the air volume is changed from a first air volume to a second air volume different from the first air volume by the user, the air volume setting unit maintains the air volume as the second air volume, irrespective of the information on the processing job acquired by the acquisition unit, until the air volume is changed from the second air volume to an air volume different from the second air volume by the user.
US11358817B2 Skew correction structure
A correction structure arranged in a feeding path of a document processing device, comprising: a transmitting means consisted of at least a pair of roller sets which are arranged symmetrically on the two sides of the feeding path for transmitting the card evenly, a correcting means consisted of a platform movably arranged at the downstream to the roller set, a receptacle formed on the platform, an elastic object arranged in the receptacle for returning the platform to a predefined location, a back wall extended from the platform toward the feeding path, an opening formed on the back wall to let a card go through, and a friction pad arranged at the bottom of the opening to partly jam the opening, wherein the width of the friction pad is less than the width of the feeding path so the friction pad only contacts the center of the card while transmitting the card.
US11358812B2 Method and apparatus for controlling article delivery device, and refrigerator
The present disclosure relates to the technical field of intelligent household appliances, and more particularly, to a method for controlling an article delivery device, the method including: detecting whether an article delivery device is in a wireless charging area, and charging the article delivery device according to a battery power of the article delivery device, controlling the article delivery device to be loaded according to a received user instruction and a target position after the battery power of the article delivery device reaches a set threshold value, and controlling the article delivery device to move to the target position after the article delivery device is loaded.
US11358807B2 Transfer device and transfer method
A transfer device, for transferring components at high speed and inspecting the components, includes a first transfer mechanism including a first transfer section including a first transfer surface that moves along a first transfer path connecting a loading position to a delivery position, and a second transfer mechanism including a second transfer section that moves along a second transfer path connecting a receiving position spaced from the delivery position by a first distance to a discharging position. The second transfer section includes a second transfer surface that continuously rotates about a rotation axis along the second transfer path. A moving direction of the first transfer surface at the delivery position intersects a moving direction of the second transfer surface at the receiving position in a plan view of the first transfer surface. The second transfer mechanism includes a generator that generates an attraction force toward the second transfer surface.
US11358805B2 Flexible hopper for a conveyor system
Some examples described herein include a flexible hopper for a conveyor system. The flexible hopper may include a hopper weldment attached to a frame of the conveyor, wherein the hopper weldment surrounds a charge end of the conveyor, a flexible connector that is attached to the hopper weldment and configured to enable an opening of the flexible hopper to expand or contract, and a flexible skirt that is folded over the flexible connector. The flexible skirt may include a plurality of flexible strips configured to form an enclosure between the flexible connector and the hopper weldment.
US11358802B2 Pallet conveying apparatus, component mounter, pallet conveying method
The turntable turnable about the table turning axis and the turning hooks mounted on the turntable turnably about the hook turning axes separated from the table turning axis are provided. By transmitting the turning of the turntable to the turning hooks, the pallet is conveyed by the engaging rollers provided on the turning hooks. Particularly, the turning hooks displace the engaging rollers in the pull-out direction by turning about the hook turning axes with respect to the turntable in the direction opposite to the turning direction of the turntable while turning about the table turning axis together with the turntable. Thus, the engaging rollers move along paths relatively close to straight lines. In this way, the pallet can be conveyed while the engaging rollers engaged with the pallet are moved along the paths close to the straight lines.
US11358801B2 Differential impulse conveyor
A differential impulse conveyor system including detectable markers disposed in a series on a moving component of the conveyor system. A stationary sensor disposed in close proximity to the markers generates a signal when the moving component is in a first range of motion to dispose the markers proximal to the sensor, and the sensor either fails to generate a signal when the moving component is not within the first range of motion. The sensor signal causes a current conditioning device to condition current from a current source to operate a motor to power the conveyor tray at a first rate of acceleration in a first mode, and the lack of the signal causes the current conditioning device to operate the motor to power the conveyor tray at a second rate of acceleration in a second mode. Markers may be positionable to optimize the timing of the current modes.
US11358798B2 Display panel conveying system and conveying method
The present application discloses a display panel conveying system and a conveying method. The display panel conveying system includes a cassette, a console, a crane, and a movable cassette conveying device, where the console has at least two sets.
US11358796B2 System and method for storing water in an underground reservoir and managing the same
An underground water storage system has a system for preventing water invasion into the near surface soil layers, thereby preventing water intrusion which may be detrimental to desired surface uses for the land, such as agricultural, recreational, residential or commercial uses.
US11358794B2 Systems and methods for processing objects including a linear gantry system
A storage, retrieval and processing system for processing objects is disclosed. The storage, retrieval and processing system includes a plurality of storage bins providing storage of a plurality of objects, where the plurality of storage bins being in communication with a retrieval conveyance system, a programmable motion device in communication with the retrieval conveyance system for receiving the storage bins from the plurality of bins, where the programmable motion device includes an end effector for grasping and moving a selected object out of a selected storage bin, and is adapted for movement of the programmable motion device along a first direction, and a plurality of destination bins that are provided in at least one linear arrangement along the first direction of movement of the programmable motion device.
US11358790B2 Spill proof substance disposal system
The Spill Proof Substance Disposal System (95) allows for the storage and removal of liquid (e.g. oils) and semi-liquid substances (e.g. greases) (“stored substances””) being transported in a transfer vessel (90). The Spill Proof Substance Disposal System (95) is vandal and theft proof. The Spill Proof Substance Disposal System (95) provides for a quick and efficient way to store and to remove the stored substances. The Spill Proof Substance Disposal System (95) comprises a container (100), a cradle (200), a hinge (300), and a screen (400). The Spill Proof Substance Disposal System (95) may additionally include a cover (500). The Spill Proof Substance Disposal System (95) may additionally include a lock (600). The Spill Proof Substance Disposal System (95) may further comprise a fast substance removal system (700).
US11358789B2 Air flowing garbage can assembly
An air flowing garbage can assembly for includes a garbage can that has a garbage bag being removably positioned therein to store garbage. The garbage can has a plurality of air holes integrated into the garbage can to pass air into an interior of the garbage can. A plurality of conduits is each coupled to the garbage can and each of the conduits is positioned in an interior of the garbage can. Each of the conduits is in fluid communication with a respective one of the air holes in the garbage can. In this way each of the conduits ventilates the interior of the garbage can when the garbage bag is removed from the garbage can thereby inhibiting a vacuum from forming in the garbage can.
US11358787B2 Modular cargo containers with surface connectors
Certain aspects of the present disclosure provide a modular container, including: six sides, wherein: each side of the six sides of the modular container comprises at least four surface connectors, each surface connector of the at least four surface connectors comprises at least two connector elements, at least one connector element of the at least two connector elements is of a first type, and at least one connector element of the at least two connector elements is of a second type; and an access door in at least one side of the six sides.
US11358785B2 Silo system and bulk material management system
A silo system includes a storage chamber, an intake pathway associated with the chamber, and a discharge pathway associated with the chamber. The system further includes one or more material sensors associated with the chamber, a plurality of actuators, and a controller that is communicatively coupled to the one or more material sensors and to the one or more actuators. The plurality of actuators enable a deposit of additional material from a transport container into the chamber through the intake pathway at least partially simultaneous with a discharge of material from the chamber through the discharge pathway into an operational silo. The material sensors provide indications of the amount of bulk material in the chamber and the controller is configured to control the one or more actuators in response to sensor data from the one or more material sensors to provide for deposit of material simultaneous with discharge of material.
US11358771B2 Tamper-evident multi-compartment article dispensing package and tamper-evident cover sheet for multi-compartment article dispensing package
A multi-compartment package for dispensing plural items is disclosed. The package includes plural individual sealed compartment units which are releasably secured to each other. Each compartment unit includes a flanged base from which a chamber depends. The chamber holds an item to be dispensed and is surrounded by a flange. A closure member, in the form of a respective portion of a frangible cover sheet, is adhesively secured to the flange of each compartment unit. Each closure member includes plural tamper-evident cuts therein located adjacent respective corners of the closure member to initiate a tear upon attempted removal of the closure member from the flange of its associated compartment unit.
US11358770B2 Contact lens blister pack label and method for adjoining blister packs
Contact lens packaging (2) includes two or more individual, sealed blister packs (1) coupled together by a connecting label (5), which includes a uni-axial shear polymer film (6). The connecting label (5) is arranged and oriented such that the tear direction of the polymer film (6) is parallel to a line (A) bisecting adjacent blister packs (1). Methods of binding together two or more blister packs (1) are also described.
US11358769B2 Composite package
A composite package (100) comprises a plurality of primary packages (102) which are gathered into at least one secondary package (106) that comprises an envelope (104) about at least some of said primary packages (102), and a handle (108), and is characterized in that the handle (108) is mobile between a retracted first position substantially enclosed within said composite package (100), and an extracted second position projecting at least partially from said composite package (100).
US11358767B2 Laser sample chamber for deep space exploration
A laser sample chamber for deep space exploration includes a sample chamber base and a sample chamber top cover. The sample chamber base is a hollow cylinder with bottom end being sealed and top end being open, and an internal cavity in the hollow cylinder is provided for receiving sample plates; and a body of the sample chamber top cover is a hollow cylinder with a top end being sealed and a bottom end being open, and the body consists of a plurality of components which comprise a hollow annulus positioned at a middle of the sample chamber top cover, a circular viewing window positioned at an opening at a top end of the hollow annulus, and a threaded port positioned at an opening at a bottom end of the hollow annulus and protruding outward.
US11358765B2 Double button cream bottle
Disclose is a double button cream bottle, which comprises a bottle body and a bottle cap for closing the bottle body, wherein an inner ring of the bottle cap is provided with an abutment ring, an upper limit of the abutment ring is provided with a button ring, and the button ring comprises two buttons disposed opposite each other and an elastic ring connecting the two buttons; an upper portion of the bottle body is convexly and radially provided with a flange, a recess is formed at a lower end of the flange, and when the bottle body is inserted into the bottle cap, the elastic ring is snapped in the recess and limits the flange between an inner end of the bottle cap and the elastic ring; an upper end of the bottle body is covered with a cover plate, the cover plate is provided with an elastic piece upwardly tilted, and when it is closed, the elastic piece is limited between the inner end of the bottle cap and the cover plate; a side wall of the bottle cap is provided with button grooves corresponding to the buttons, and when the two buttons are simultaneously pressed, the elastic ring is pressed and deformed and disengages from the recess, so that the flange disengages from the limiting of the elastic ring; and the bottle body is separated from the bottle cap by the elastic force of the elastic piece, and through the above arrangement, the bottle body and the bottle cap can disengage from and be closed to each other without accidental opening.
US11358763B2 Child resistant storage container
A child-resistant storage container comprising two rigid boxes of relatively equal height and width manufactured from or coated with materials that produce enough friction between the contact points of the boxes to retain the inner box in the outer box when shook.
US11358756B2 Press-on caps and sealed containers comprising the press-on caps
A system for capping a mouth of a container may include: a press-on cap for irreversibly capping the mouth of the container, wherein the press-on cap is made of polymeric material able to withstand high-temperature sterilization and wherein the press-on cap may include: a tubular sleeve extending along an axis of extension and configured to be irreversibly locked to the mouth of the container; a rim that radially projects out of the tubular sleeve at an end of the press-on cap; a capping wall oriented transverse to the tubular sleeve and extending from the rim over a front surface delimited by the rim, wherein the front surface faces outwardly; and a plurality of protrusions, which extend out of the front surface. The front surface may have a height variation relative to the rim across the front surface ranging from −1% to 1% of a characteristic dimension of the capping wall.
US11358753B2 Equipment transfer bag
An equipment containment and transport assembly (20) includes an open-top equipment-receiving primary bag (22) having upstanding sidewall structure (26) equipped with lifting lug opening pairs (30, 32), and a bottom wall (28). The assembly (20) further has a flexible sleeve (24), which is secured to the sidewall structure (26) and is shiftable between a ready position surrounding the sidewall structure (26) and a deployed position extending upwardly for closure or the assembly (20). When deployed, the sleeve (24) covers the lug opening pairs (30, 32). The assembly (20) is particularly useful for containment and shipping of electrical transformers.
US11358751B2 Storage container systems and methods
A container system or apparatus is provided which includes a main container having a bottom wall and a plurality of sidewalls integrally connected to the bottom wall, the bottom wall and sidewalls having an interior face defining a first interior holding area, a sub-container having a bottom wall and a plurality of sidewalls integrally connected to the bottom wall, the bottom wall of the sub-container and the sidewalls of the sub-container having an interior face defining a second interior holding area, and a lid formed to removably mate with a top portion of the sub-container to enclose the second interior holding area, the lid and the sub-container forming a structure formed to removably mate with a top portion of the main container to enclose the first interior holding area.
US11358750B2 Resealable can lid
The invention relates to a can lid of a conventional design, in particular intended for beverage cans, whose special feature comprises the fact that a substantially ring-shaped molded plastic part is fastened to the lower side of the lid surface surrounding the opening region to form an opening that is sealingly reclosable, in that a plastic stopper part is fixedly connected to the lower side of the tongue tab that is upwardly pivotable during the opening procedure and sealingly engages into the molded part, and in that the peripheral contour of the tongue tab is preferably disposed in the region of the molded part at a predefinable spacing from the stopper part.
US11358749B2 Packaging containers and related methods
The disclosed packaging containers may include a body including a sidewall and at least one top flap for at least partially covering an opening of the body when assembled and perforations in the sidewall of the body. The perforations may include a lower perforation having a first end portion and a second end portion; a first side perforation extending upward toward the top flap from the first end portion of the lower perforation; and a second side perforation extending upward from the second end portion of the lower perforation, wherein the first side perforation and the second side perforation converge toward each other as they extend upward from the lower perforation. Various other packaging containers, systems, and methods are also disclosed.
US11358745B2 Separator assembly for modular filling systems
A separator assembly for separating adjacent flexible bags in a filling assembly includes a body defining an opening therethough, a surface defined on the body within the opening, a clamp movable in the opening and configured to selectively contact the surface, a separator blade movable within the opening, a rail, and a rail guide configured to slidably engage with the rod. The separator assembly is movable along the rail. Methods of moving the separator assembly are also disclosed.
US11358733B2 Optimum idle descent start point display based on current conditions
A system and method for computing and displaying a fuel optimal idle deceleration start point which minimizes the overall auto throttle movement keeping the throttle at idle detent throughout the maneuver thus minimizing the fuel burn and stress on engine. The need for speed brakes deployment is also reduced because the deceleration distance length is accordingly adjusted based on current parameters. The accurate solution takes into account the current condition such as aircraft weight, altitude and speed and environmental parameters such as wind and temperature. The computed deceleration start point is displayed on map/navigation and vertical display for enhanced flight crew awareness.
US11358730B1 Systems and methods for an aircraft motion observer in an electric aircraft
A command model connected to plurality of flight components of an electric aircraft and comprises a circuitry configured to detect a predicted state and a measured state datum, transmit predicted state datum to an actuator model, and transmit measured state datum to a plant model. An actuator model connected to the sensor configured to receive the predicted state datum and generate a performance datum. A plant model connected to the sensor configured to receive measured state datum and performance datum from the actuator model, transmit a feedback path to controller, and generate an inconsistency datum as a function of the measured state datum and the performance datum. A controller communicatively connected to the sensor, wherein the controller is configured to receive the inconsistency datum from the plant model and apply a torque to the aircraft as a function of the inconsistency datum.
US11358727B2 Method and apparatus for predicting conditions favorable for icing
A method and apparatus for predicting conditions favorable for icing, includes sensing a value indicative of a thermal cycling period, comparing, the sensed thermal cycling period with a threshold value, determining, if the sensed thermal cycling period satisfies the threshold value, and indicating, by the controller module, that conditions favorable for icing are present when the sensed thermal cycling period satisfies the threshold value.
US11358725B2 Three wheel and simple cycle aircraft environmental control system
An environmental control system of an aircraft includes a ram air circuit including a ram air shell having a plurality of heat exchangers positioned therein, the plurality of heat exchangers including a first heat exchanger, a second heat exchanger, and a third heat exchanger. The ram air circuit is configured and arranged so that a first medium received at the first heat exchanger passes through the first heat exchanger and then through the third heat exchanger and so that a second medium received at the second heat exchanger passes through the second heat exchanger. A compressing device is arranged in fluid communication with the ram air circuit.
US11358722B2 Passenger seat with support structure defining empty space
A passenger seat includes a bottom support to be connected to the aircraft floor, a seat pan frame, and a support structure interconnecting the seat pan frame to the bottom support. A front support member defines a frontmost portion of the support structure, and has a top end connected to a front end of the seat pan frame and a bottom end connected to the bottom support. The front end of the seat pan frame is forwardly offset from a front end of the bottom support and the top end of the front support member is forwardly offset from its bottom end such that an empty space is defined across a width of the seat between the seat pan frame and the floor, forwardly of the support structure, forwardly of the bottom support, and rearwardly of a vertical plane aligned with the front end of the seat pan frame.
US11358716B2 System and method for airborne wind energy production
A system for electric power production from wind includes a glider having an airfoil, an on-board steering unit, a flight controller for controlling the steering unit, and a connection unit for a tether. The system further includes a ground station including a reel for the tether, a rotating electrical machine connected to the reel, and a ground station controller for controlling the reel and the rotating electrical machine. A master controller operates the system in at least first and second operation modes. In the first operation mode electric power is produced with the rotating electrical machine from rotation of the reel caused by reeling out the tether using a lift force generated upon exposure of the airfoil of the airborne glider to wind. In the second operation mode, the reel is driven by the rotating electrical machine, thereby reeling in the tether onto the reel.
US11358714B2 Aircraft
An aircraft includes a fuselage and propellers, wherein the propellers can be retracted beneath the fuselage.
US11358713B2 Multicopter with boom-mounted rotors
A multicopter aircraft with boom-mounted rotors is may include a fuselage; a port side wing coupled to the fuselage; and a starboard side wing coupled to the fuselage. Each of the wings has mounted thereto one or more booms, each boom having a forward end extending forward of a corresponding wing to which the boom is mounted and an aft end extending aft of said corresponding wing to which the boom is mounted. The aircraft further includes a first plurality of lift rotors, each rotor in said first plurality being mounted on a forward end of a corresponding one or said booms; and a second plurality of lift rotors, each rotor in said second plurality being mounted on an aft end of a corresponding one or said booms. Each rotor produces vertical thrust independent of the thrust produced by the other rotors.
US11358712B2 Multicopter with angled rotors
A multicopter with angled rotors includes a fuselage and a plurality of rotors. At least some of the rotors are disposed on opposite sides of the fuselage and each is oriented at a corresponding angle to a substantially horizontal plane of the aircraft, the angle being of a magnitude such that a plane of rotation of the rotor does not intersect at least a critical portion of the fuselage.
US11358706B2 Automated weight balancing for automated guided vehicle
Systems and methods for an Automated Guided Vehicle (AGV) capable of automatically balancing large and heavy objects for transport through a facility. One embodiment is an Automated Guided Vehicle (AGV) including a balancing plate configured to support a load, load sensors configured to detect a weight distribution of the load, and an actuator configured to shift the balancing plate laterally. The AGV also includes a weight balancing controller configured to determine a center of gravity of the load based on the weight distribution detected by the load sensors, to determine that the center of gravity of the load is vertically misaligned with a center of gravity of the AGV, and to direct the actuator to shift the balancing plate laterally to move the center of gravity of the load toward vertical alignment with the center of gravity of the AGV.
US11358700B1 Devices and methods for extending aircraft cargo bays with replacement tailcones
Systems and methods for extending the interior cargo bay of fixed-wing cargo aircraft into a replaceable tailcone bay are disclosed. The system includes an aircraft and a removable tailcone configured couple to the aft end of the fuselage. The aircraft fuselage includes a cargo bay and an aft end opening into the cargo bay. The tailcone, when attached, encloses the aft end opening the cargo bay. The tailcone can include an interior volume configured to extend the fuselage cargo bay such that the interior volume defines an aft end of a cargo bay of the cargo aircraft. In some examples, the tailcone includes a plurality of segments, which can be configured to extend from the aft end of the aircraft to adjust a length of the cargo extension provided by the tailcone.
US11358697B1 Systems and methods for rotatably supporting counter-rotating propeller shafts in a marine propulsion device
A system for rotating inner and outer propeller shafts via a driveshaft. The system includes a stub shaft extending between forward and aft ends, the aft end having an engagement feature for engaging with the inner propeller shaft such that rotating the stub shaft rotates the inner propeller shaft. A reverse gear and a forward gear are each rotatably coupled to the stub shaft. The reverse gear and the forward gear mesh with the driveshaft and are engageable to become rotatably fixed to the stub shaft such that rotating the driveshaft rotates the stub shaft in reverse and forward directions, respectively. An outer driving gear is coupled to the inner propeller shaft to rotate therewith. An outer driven gear is coupled to the outer propeller shaft and a pinion rotatably coupling the outer driving gear to the outer driven gear such that rotation of the outer driving gear rotates the outer propeller shaft.
US11358696B2 Method of starting an internal combustion engine of a hybrid propulsion system in a marine vessel and a hybrid propulsion system in a marine vessel
A method of operating a marine vessel hybrid propulsion system having a propulsion shaft and a propeller, an internal combustion piston engine in force transmission connection with the propulsion shaft, and an electric motor-generator in force transmission connection with the propulsion shaft and/or with the piston engine. The internal combustion piston engine can be started by applying electric power from an on-board power source to the electric motor-generator and rotating the internal combustion piston engine by the electric motor-generator and rotational speed of the internal combustion piston engine is accelerated to a predetermined limit rotational speed without attempting to start the internal combustion piston engine, and only after the rotational speed of the internal combustion piston engine reaches the predetermined limit rotational speed, the internal combustion piston engine is started.
US11358689B2 Yacht preserver
A nonlimiting example of a yacht preserver includes a handle, an inflator device connected to an upper end of the handle and an inflatable bladder connected to a lower end of the handle. In this nonlimiting example, the inflator device includes a gas canister that is connected to the inflatable bladder by a tube and is configured to deliver gas to inflate the bladder upon activation. The yacht preserver may be used to seal an opening of a yacht by placing the uninflated bladder near the opening in the yacht and activating the inflator device allowing the bladder to expand to seal the opening.
US11358686B2 Righting devices for assisting with righting capsized watercraft, and watercraft incorporating such righting devices
Righting devices that provide foot and/or hand holds to allow users to manually right capsized watercraft. In some embodiments, each righting device is configured to be secured to a hull bottom so as to extend outwardly from the surface of the hull bottom. In some embodiments, each righting device includes at least one receptacle that is recessed relative to a hull bottom. Righting devices of the present disclosure may, for example, be retrofitted to existing hull bottoms. Righting devices of the present disclosure may be formed monolithically and integrally with hull bottoms during construction thereof. The present disclosure is also directed to methods of using righting devices of the present disclosure, as well as to kits that include one or more righting devices, installation instructions for locating and installing one or more righting devices, and/or use instructions describing how to use the righting device(s) to right a capsized watercraft.
US11358684B2 Audio system for a vehicle and method of installing the audio system
An audio system for a vehicle, such as a personal watercraft, having a vehicle body dimensioned for receiving a side-view mirror, includes a speaker pod that includes a housing dimensioned for supporting a speaker operable to produce sound, and a mounting member for mounting the speaker pod to the vehicle body in place of the side-view mirror. A portion of the housing is shaped similarly to a corresponding portion of the side-view mirror. A method of installing an audio system on a vehicle having a vehicle body dimensioned for receiving a side-view mirror involves: (a) determining that the side-view mirror is removed from the vehicle body; and (b) mounting a speaker pod of the audio system, along a mounting member of the speaker pod, to the vehicle body in place of the side-view mirror such that a housing of the speaker pod supports a speaker operable to produce sound.
US11358681B2 Weather guard for a power boat
A rigid weather guard for a center console of a power boat includes a rapidly deployable protective shield. The shield has a top edge, a bottom edge, a first side edge that is pivotably connectable with a portion of the boat, and a second side edge that is configured for connection with a gunwale of the power boat. The pivotable connection of the first side edge provides movement between an open and closed position. When in the open position, the second side edge is connected with the gunwale securing the shield in place to block adverse weather. Preferably, the protective shield has a transparent portion.
US11358680B1 Apparatuses and methods for fluid pumps and pump adapters
A pump intake adapter for pumping shallow levels of fluid from a surface to be drained, the pump intake adapter including a connection on the pump intake adapter to convey the fluid away from the pump intake adapter; an intake surface on the pump intake adapter; and a portion of the intake surface of the pump intake adapter that in operation does not contact the surface to be drained, and creates an open conduit between the pump intake adapter and the surface to be drained through which fluid may flow, the open conduit being in fluid communication with the connection on the pump intake adapter. Other systems and methods are provided.
US11358677B2 Bicycle component
A bicycle component includes a drive unit and a battery. The drive unit includes a housing mounted on a bicycle frame, a crankshaft provided to a first portion of the housing, and a propulsion assist motor provided to a second portion of the housing. The battery is electrical connected to the propulsion assist motor to supply electrical power to the propulsion assist motor. The propulsion assist motor includes a rotational axis extending in a direction intersecting a direction in which the crankshaft extends. At least part of the second portion and at least part of the battery are accommodated in the frame in a state in which the second portion and the battery are arranged next to each other in a direction parallel to the rotational axis of the propulsion assist motor and the battery is coupled to the second portion in an attachable and detachable manner.
US11358671B2 Leaning vehicle
A leaning vehicle includes a caliper and an electric motor supported at a same position in a vehicle body frame. Provided that a position opposed to a pad in a plate when a left front wheel is located in an uppermost end in the vehicle-body-frame upward direction in a movable region of the left front wheel and a right front wheel is located in a lowermost end in the vehicle-body-frame downward direction in a movable region of the right front wheel is defined as a left leaning end portion position and a position opposed to the pad in the plate when the left front wheel is located in the lowermost end in the vehicle-body-frame downward direction in the movable region of the left front wheel and the right front wheel is located in the uppermost end in the vehicle-body-frame upward direction in the movable region of the right front wheel is defined as a right leaning end portion position, the electric motor is disposed in a motor disposition region spaced away from a movable region of the plurality of link members by a distance equal to or smaller than a distance between the left leaning end portion position and the right leaning end portion position.
US11358669B2 Saddle riding vehicle
A saddle riding vehicle includes a head pipe, left and right main frame pipes, a fuel tank supported on the left and right main frame pipes, an upper gusset plate provided between the left and right main frame pipes, a lower gusset plate provided below the upper gusset plate with an interval, a stay attached to the lower gusset plate below the upper gusset plate, and a fastening bolt configured to detachably fasten the lower gusset plate and the stay.
US11358668B2 Divisible legs apron for a motor vehicle
A legs apron for a motor vehicle includes a first part of apron having anchoring elements for removably anchoring the first part of apron to the motor vehicle, a second part of apron configured to at least cover the legs of a driver of the motor vehicle, a coupling system operatively interposed between the first and the second part of apron for removably coupling the first and second part of apron to each other, the coupling system defining a junction line between the first and second part of apron when the first and second part of apron are coupled together, where the apron further includes a waterproofing element arranged to waterproof the junction line.
US11358655B2 Modular truck bed
A truck bed member includes a rectangular top side with a long side along a first axis. An interlocking side is fixed perpendicular to the top side along a first edge of the top side parallel to the first axis and includes an interlocking member along an edge opposite the interlocking side coupled to the top side. An interlock receiving side is fixed perpendicular to the top side along a top side second edge opposite the first edge and parallel to the first axis. The interlocking side and the interlock receiving side are parallel to one another and extend a same direction from the top side. The interlock receiving side includes an interlock receiving member along an edge of the interlock receiving side opposite the edge coupled to the top side. The interlocking member is configured to couple to the interlock receiving member of a different truck bed member.
US11358652B2 Composite floor with integrated conduit
A cargo vehicle is disclosed having a composite floor assembly with at least one conduit extending along a length of the composite floor assembly. The at least one conduit may include a first internal cavity and a second internal cavity. The first internal cavity may be configured to route at least one vehicle component. The second internal cavity may be configured to receive at least one vehicle component or a plurality of mechanical fasteners. The mechanical fasteners may be used to couple a base rail to the composite floor assembly.
US11358651B2 Structural component
A motor vehicle front end having a structural component that has a first structural element for absorbing mechanical forces. The first structural element surrounds a spatial region, at least in part, such that a cavity is formed in the interior of the first structural element. The first structural element has a surface region that defines said cavity. The structural component has at least one second structural element which is connected to the first structural element. For the purpose of mechanical reinforcement of the first structural element, the structural component has at least one reinforcing element. The reinforcing element supports a portion of the surface region. The first structural element is composed of at least two separate structural element parts.
US11358649B2 Rear vehicle-body structure of vehicle
A vehicle-body structure for suppressing deformation of a lift gate opening is provided. Embodiments include a vehicle having a rear annular framework formed from a cross member, side braces, connecting members, and a rear header; a rear suspension on lower surfaces of side pillars in the same position as the cross member in a vehicle front-rear direction; and wheel well inner portions on the vehicle rear side with respect to the cross member, each having an upper end having a damper supporting portion for mounting a suspension damper. The side braces each connect a place near the cross member and a place near the damper supporting portion to each other in a vehicle up-down direction; and the connecting members each connect a place near each end portion of the rear header in a vehicle width direction and the place near the damper supporting portion to each other.
US11358636B2 Vehicle drive transmission and electrically assisted steering system
A transmission for a vehicle, particularly a skid-steered vehicle, that employs motive power from a prime mover delivered through an input shaft to drive left and right drive shafts at a nominal speed and input power from an electric motor to vary the speed of the left and right drive shafts according to steering commands from a steering control structure. The speed of the left and right drive shafts is directly related to a speed of the input shaft and the nominal speed of the left or right drive shaft is varied upwardly or downwardly by a ratio of the speed of the steering shaft via a speed varying structure. The speed of the left and right drive shafts is simultaneously varied in opposite directions (i.e. upwardly and downwardly) relative to the nominal speed by an equal number of rotations.
US11358635B2 Reverse switch activation mechanism
A reverse switch activation mechanism includes forward and reverse pedals connected to a control arm for pivoting the control arm in first and second directions. A cam surface extends from the control arm and activates a reverse switch if the reverse pedal is partially depressed. A transmission control rod is connected to the control arm through a lost motion slot and moves rearwardly if the reverse pedal is depressed further after activating the reverse switch. A control rod keeper on the control arm biases the control rod pin to a first side of the lost motion slot.
US11358633B2 Mobility vehicle
In some embodiments, a vehicle may include a frame having longitudinal axis. The vehicle may include a steering assembly having a steering input and at least one wheel. The steering assembly may be coupled to the frame and configured to steer the vehicle based on input from a steering input. The vehicle may include a first drive wheel and a second drive wheel. The vehicle may include a steering position sensor configured to detect steering input including a position of the steering input and at least one of i) a rate of change of position of steering input and ii) steering position time. The vehicle may include at least one controller configured to process a signal from the steering position sensor and, in response to the processed signal, drive the first drive wheel and the second drive wheel, the first drive wheel being driven independent of the second drive wheel.
US11358628B2 Apparatus and method for controlling motor driven power steering system
An apparatus for controlling an MDPS system may include: a column torque sensor configured to sense column torque applied to a steering column of a vehicle; a vehicle velocity sensor configured to sense vehicle velocity of the vehicle; an MDPS basic logic unit configured to decide a first assist command current for driving an MDPS motor in a manual driving mode of a driver; an autonomous driving control unit configured to decide a second assist command current for driving the MDPS motor in an autonomous driving mode of the vehicle; and a mode switching control unit configured to decide a weight into which the driver's steering intention is reflected, and apply the decided weight to the first and second assist command currents to decide a final assist command current for driving the MDPS motor when the vehicle is switched from the autonomous driving mode to the manual driving mode.
US11358621B2 System for monitoring and controlling shopping cart usage
A system for monitoring and controlling shopping cart usage comprises a wheel assembly that attaches to a shopping cart. In some embodiments the wheel assembly includes a wheel, a brake that can be activated to inhibit rotation of the wheel, a controller that controls the brake, a VLF receiver, and an RF transceiver. The RF transceiver may, for example, operate in a 2.4 GHz frequency band. In some implementations, the RF transceiver may be used to detect entry of the shopping cart into a checkout area of the store, and the VLF receiver may be used to detect that the shopping cart is exiting the store. The controller may activate the brake if the shopping cart attempts to exit the store without first passing through a checkout area.
US11358613B2 Autonomous vehicle and service providing system and method using the same
Disclosed herein are an autonomous vehicle and a service providing system and method using the same. The autonomous vehicle includes a navigation system setting, as a destination, a service zone adjacent to a parking lot when there is a previously registered vehicle service input through a user terminal, and setting, as a destination, the parking lot adjacent to the service zone after completion of the previously registered vehicle service, and an operation system moving the vehicle to the destination through autonomous driving. One or more of the autonomous vehicle, the user terminal, and the server may be associated with artificial intelligence, a robot, augmented reality (AR), virtual reality (VR), or the like.
US11358611B2 Express decision
A system includes a processor to: receive a description of a current decision that includes selecting an option; repeatedly display the description; for each option, receive an indication of selection of scale text specifying a degree of intensity or intensity for achieving or avoiding a possible outcome of the option, and derive an overall motivation based on the at least one selection; identify a best option based on the overall motivations; display the best option; compare the overall motivation of the best option to a threshold; in response to being less than the threshold, display a warning and a prompt for the operator to further consider the current decision; compare the overall motivation of the best option to the others; and in response to not exceeding all other overall motivations, by at least a threshold of difference, present a proximity warning and the prompt.
US11358609B2 Method for warning a driver of a motorcycle as well as ride assistant controller and motorcycle implementing such method
A method for warning a driver of a motorcycle and a ride assistant controller for implementing or controlling such method are described. The method includes monitoring traffic situations based on signals from at least one sensor; upon detecting a critical traffic situation based on the signals from the at least one sensor, warning the driver by inducing an acceleration change onto the motorcycle; wherein a current lean angle of the motorcycle is monitored and a manner and/or degree of inducing the acceleration change onto the motorcycle is set taking into account the current lean angle of the motorcycle.
US11358607B2 Vehicle control device
A vehicle control device includes a steering wheel including an annular rim portion and a spoke portion that extends inward from the rim portion, an indicator that is disposed on the spoke portion and is able to be lit, and a controller that controls a lighting state of the indicator according to a state of driving assistance.
US11358604B2 Sensor system for a vehicle and method for monitoring a sensor
A sensor system for a vehicle, including a first sensor that detects at least one collision-relevant physical variable and outputs at least one corresponding first sensor signal, and at least one second sensor that, independently of the first sensor, detects at least one collision-relevant physical variable and outputs at least one corresponding second sensor signal, and an evaluation and control unit that receives the at least one first sensor signal and the at least one second sensor signal and evaluates them for the collision detection. A method is also described for monitoring a sensor. The evaluation and control unit uses at least one second comparison signal that is based on the at least one second sensor signal of the at least one second sensor to monitor the first sensor.
US11358603B2 Automated vehicle profile differentiation and learning
A system for a vehicle includes a memory configured to store modeling parameters, generated using an algorithm that assigns relevance scores to features, that specify information indicative of how configuration data including information indicative of use of features of the vehicle classifies which user is currently using the vehicle. The system also includes a processor programmed to monitor the vehicle for the configuration data, identify a most likely user profile using the modeling parameters according to the configuration data, and apply settings of the user profile to the vehicle.
US11358594B2 Lane change assist device
A yaw angle return controller is configured to end first yaw angle return control at a predetermined time when a value which is calculated by adding yaw angle detected by a lane recognition device at a predetermined time and an estimated yaw angle change amount is the same as yaw angle at lane change start time under a state where the first yaw angle return control is being executed. The predetermined time comes after the first start time and before the first finish time. The estimated yaw angle change amount is calculated by multiplying the yaw rate detected by a yaw rate sensor at the predetermined time by a predetermined time period for foreseeing.
US11358592B2 In-vehicle processing apparatus and in-vehicle processing system
An in-vehicle processing apparatus that executes control of causing a vehicle to perform automated traveling from a predetermined position to a parking space and causing the vehicle to perform automated entry into the parking space, is configured to include a notification control section that causes a portable electronic device carried by a user to display a parking position notification display in which a position of the parking space entered by the vehicle through the automated entry and the predetermined position are superimposed on an image.
US11358590B2 Switching method of automatic driving mode, apparatus and readable storage medium
Provided are a switching method of an automatic driving mode, an apparatus, and a readable storage medium. The method includes determining an identity of a user riding an automatic driving device; determining, according to the identity of the user, a target automatic driving mode matched with the identity of the user from multiple pre-stored automatic driving modes; and controlling, according to the target automatic driving mode, the automatic driving device to perform a current automatic driving task. The method can adopt different automatic driving modes to perform a current automatic driving task according to differences of identities of users and provide the users with experiences riding an automatic driving device that are more suited to their requirements.
US11358589B1 Engine control module park lock solenoid control for hybrid transmission
Non-inverted park lock systems and methods include an engine controller configured to control an engine of a vehicle in communication with a separate transmission controller via a controller area network (CAN), wherein the transmission controller is configured to control a transmission of the vehicle; and a conductor connecting the engine controller to a park lock solenoid disposed in the transmission and configured to move a park pawl to engage/disengage park. The engine controller keeps the park pawl disengaged from park during a power loss malfunction at the transmission controller and the transmission controller keeps the park pawl disengaged from park during a power loss malfunction at the engine controller by maintaining hydraulic pressure in the transmission at a threshold level until park is requested via the shifter.
US11358587B2 Engine control device for vehicle including acceleration assist control
An engine control device for a saddle riding vehicle includes a mechanical centrifugal clutch for connecting and disconnecting driving force from an engine to a driving wheel, a throttle operator to adjust output power of the engine, a motor to rotate a crankshaft of the engine, and a control unit to control the motor and a fuel injection system. The control unit executes injection stopping control for stopping fuel injection during deceleration of the vehicle and executes, when an opening operation of the throttle operator is performed after an engine speed becomes equal to or lower than a centrifugal clutch disconnection speed at which the centrifugal clutch is disconnected, acceleration assist control for rotating the crankshaft with the motor.
US11358582B2 Controller and control method for hybrid vehicle
A controller for a hybrid vehicle is configured to execute a shifting assist process of increasing torque of a motor when performing power-on downshift of an automatic transmission and an upper limit assist torque setting process of setting an upper limit assist torque that is an upper limit value of a travel assist torque to be a smaller value when a maximum step number of the power-on downshift is large than when the maximum step number is small.
US11358581B2 Control system for hybrid vehicle
A control system for a hybrid vehicle configured to reduce fuel consumption. A controller is configured to execute a first determination to determine that a required power is less than a reference power, and a second determination to determine that a condition to start an engine is satisfied. If the answers of the first determination and the second determination are YES, a target power of the engine is set to a predetermined power which is greater than the required power, and which can be generated by consuming smaller amount of fuel. Then, the generator is driven by the engine being operated to achieve the predetermined power, and an electric power generated by the generator to be accumulated in a battery is set to a value calculated based on a difference between the target power and the required power.
US11358580B2 System for train terminal test
A system for identifying whether the braking system of a train is functioning properly such as during a train terminal test. A monitor on a rail car is used to detect abnormalities in the braking system and can report problems to a handheld terminal or a central controller in the locomotive. The monitor has a pressure sensor for measuring brake pipe pressure, auxiliary reservoir pressure, emergency reservoir pressure, and brake cylinder pressure at the rail car. The monitor also has a controller that can calculate whether brake pipe reduction resulted in the appropriate amount of brake cylinder pressure. The monitor can then provide the results locally via a visual indicator or remotely to a handheld terminal used by a train inspector or the controller in the locomotive. Testing data over time may be stored for future reference or transmitted remotely to assist with maintenance and service scheduling.
US11358578B2 Electromechanical brake booster and method for producing an electromechanical brake booster
An electromechanical brake booster, the second half housing being able to be centered on the first half housing by engaging a first mounting pin protruding from the first centering opening into the first insertion opening and by engaging a second mounting pin protruding from the second centering opening into the second insertion opening. A method for producing an electromechanical brake booster for a motor vehicle is also described.
US11358576B2 Brake power derating
A braking system is disclosed. The braking system may include a controller configured to determine a power limit for one or more brakes of a machine based on a temperature of the one or more brakes during engagement of the one or more brakes according to a commanded power. The power limit may be a power at which the temperature of the one or more brakes ceases to increase. The controller may be configured to determine a speed adjustment for the machine based on the power limit and the commanded power, and cause adjustment to a speed of the machine based on the determined speed adjustment.
US11358574B2 Brake control device for motorcycle
In this brake control device for a motorcycle, a deceleration threshold value calculation unit limits target wheel deceleration to a threshold value or less on the basis of a bank angle estimated by a bank angle calculation unit. Thus, the behavior of the vehicle body during turning of the motorcycle can be made more stable so as not to cause discomfort to a driver.
US11358573B2 Method and device for controlling a parking brake
A method for controlling a parking brake of a vehicle, including: receiving an activation signal which represents a manual operating unit of a parking brake being activated by a driver; reading a speed decrease signal which represents a value of a speed decrease of the vehicle upon receiving the activation signal; and emitting a delay signal as a function of the value of the speed decrease, wherein the delay signal is configured for delaying a complete engagement of the parking brake. Also described are a related apparatus/device, and a computer readable medium.
US11358572B2 Brake control system and method for autonomous vehicle control
A brake control system and method for autonomous vehicle control that includes a first brake pedal connected to a first brake arm, the first brake arm is connected to a first brake shaft, the first brake shaft extends a length between an upper end and lower end and includes a first actuator that expands and contracts in length. The lower end of the first brake shaft is operably connected to a first brake mechanism. An autonomous control system having a controller with microprocessor, memory and instructions is connected and controls operation of the first actuator. When the first brake shaft expands in length the first brake mechanism is engaged by the lower end of the first brake shaft thereby applying the brakes. The first brake mechanism is operable by depressing the first brake pedal in manual operation mode as well as by controlling the first actuator in autonomous operation mode.
US11358570B2 Windscreen wiper arm, particularly for automobiles
A windscreen wiper arm, particularly for automobiles, that is able to oscillate upwardly and downwardly between a downward position and an upward position. One end of the windscreen wiper arm is adapted to be pivotally connected to a mounting head mounted on a drive shaft. Another end of the windscreen wiper arm is rigidly connected to an adapter adapted to be connected to an elongated wiper blade to be placed in abutment with a windscreen to be wiped. The adapter, at the location of its connection to the wiper blade, has a U-shaped cross-section with a base and two spaced-apart legs. The U-shaped cross-section is preferably mounted offset in a plane of the base relative to a longitudinal axis of the windscreen wiper arm. The windscreen wiper arm is provided with a nozzle for spraying a washing liquid onto the windscreen to be wiped. The nozzle is detachably connected to the adapter through a key hole connection.
US11358569B2 Windshield wiper device, in particular wiper arm adapter device, wiper arm waving the windshield wiper device and windshield wiper having the windshield wiper device
The invention is based on a windshield wiper device, in particular a wiper arm adapter device, having at least one fluid connection piece (36) which delimits at least one fluid channel (38), and having at least one adapter piece (40), wherein the adapter piece (40) and the fluid connection piece (36) are constructed to be able to be moved relative to each other and are provided to be moved relative to each other during a coupling or uncoupling operation, in particular with a wiper blade (16).It is proposed that the windshield wiper device comprise at least one coupling unit (42) which is provided to close the fluid channel (38) in accordance with a position of the adapter piece (40) relative to the fluid connection piece (36).
US11358567B2 Wiper articulation system
An automobile vehicle wiper arm system includes a wiper arm base rotatably connected to a fixed structural member. A wiper arm extension is slidably disposed to the wiper arm base during wiper arm base travel about an arc of travel. A motion link is rotatably connected to the wiper arm extension and is rotatably connected to the fixed structural member. The motion link induces the wiper arm extension to outwardly displace and inwardly displace opposite to the outward displacement during wiper arm base rotation about the arc of travel. A wiper blade is connected to the wiper arm extension and traverses an oval-shaped travel arc along a vehicle windshield by the slidable displacement of the wiper arm extension during wiper arm base rotation. A linkage group connects the wiper arm extension to a wiper motor with rotation of the wiper arm base induced by operation of the wiper motor.
US11358565B1 Vehicle authentication system and vehicle authentication method based on bluetooth low energy and fingerprint
A vehicle authentication system and a vehicle authentication method based on BLE and fingerprint are provided. The vehicle authentication system includes an audio/video/navigation/telematics (AVNT) smart interconnection device, a driver-side door handle fingerprint identification device, a vehicle starting button fingerprint identification device, a fingerprint authentication controller, and a central control processor.
US11358563B2 Outside protection apparatus for vehicle
An outside protection apparatus for a vehicle includes an outside airbag device. The outside air bag device includes a first bag body, an inflator, and a second bag body. The first bag body is expandable to be overlaid on a hood of a body of the vehicle rearwardly from a front portion of the body. The inflator is configured to expand the first bag body. The second bag body is expandable from a side portion of the first bag body in a width direction of the vehicle later than the first bag body.
US11358541B2 Vehicle soundproofing structure
A vehicle soundproofing structure includes: a soundproofing mechanism configured to suppress sound from leaking outside from a vehicle by absorbing, dissipating, or cancelling sound inside a vehicle cabin, and a controller configured to enable operation of the soundproofing mechanism when the vehicle is stationary, and to disable operation of the soundproofing mechanism when the vehicle is travelling.
US11358538B2 Lining, a haul truck body comprising the same and a haul truck
The disclosure relates to a lining for a haul truck body, said lining being arranged to extend over surfaces of said haul truck body, wherein said surfaces define at least one impact region and at least one wear region; wherein said lining within said at least one impact region presents one or more impact lining elements; wherein said lining within said at least one wear region presents one or more wear lining elements; and wherein said impact lining elements have a higher impact resistance than said wear lining elements and said wear lining elements have a higher wear resistance than the impact lining elements. The disclosure further relates to a haul truck body comprising the lining and a haul truck comprising the haul truck body.
US11358537B2 Systems and methods for a piezoelectric diaphragm transducer for automotive microphone applications
Systems and methods for a transducer assembly for a vehicle having a resonating surface. The transducer assembly comprising a housing, a spacer connected to the housing, and a piezoelectric assembly disposed between the spacer and the housing. The spacer is configured to connect to the resonating surface to form an air gap between the resonating surface and the piezoelectric assembly.
US11358536B2 Detection apparatus
A detection apparatus includes a detection unit configured to detect a peripheral environment of a vehicle and a bracket configured to attach the detection unit to a vehicle body. The detection unit includes a front surface portion, a back surface portion, and side surface portions. The bracket includes a bottom wall portion and a first guiding portion configured to guide the attachment of the detection unit to the bracket. When the detection unit is attached to the bracket by diagonally inserting one end of the detection unit towards the bottom wall portion and pivoting the detection unit about a side of the one end as a rotation center, the first guiding portion restricts a position of the one end.
US11358532B2 Portable dash pouch
A dashboard pouch is provided. The dashboard pouch ensemble includes a base tray, configured to be detachably attached to an external surface, and a document pouch, configured to be inserted into a cavity of the base tray. The base tray includes a first cover, comprising a first end hingedly connected to a first side panel of the base tray, and a second end including one or more first fastening devices, and a second cover comprising a first end connected to the first side panel of the document pouch, and a second end connected to a second side panel of the base tray, and the second cover is configured to form a cavity with a base panel, side panels, and a rear panel of the base tray, wherein the second side panel includes one or more second fastening devices.
US11358530B2 Apparatus for receiving an object in a motor vehicle
An apparatus for receiving a cuboidal object, which has three side edges of different length, in a motor vehicle, having a receiving space, which has an insertion opening, the length of which corresponds at least to the length of the longest side edge of the object and whose width corresponds at least to the length of the shortest side edge of the object, but at least in sections is smaller than the length of the side edge of the object with the medium length, wherein the receiving space is of such a size that the object after being inserted through the insertion opening in the receiving space can be rotated through an angle of at least approximately 90° about its longitudinal axis and can be moved to a storage position in the receiving space.
US11358523B2 Method for assisting a driver of a motor vehicle during an overtaking operation, motor vehicle, and system
The invention relates to a method for assisting a driver of a motor vehicle during an overtaking operation. The method includes determining vehicle data, which relate to a movement of the motor vehicle and determining an intention of the driver to overtake another vehicle using the vehicle data. The method further includes determining a position of the motor vehicle and providing environment data for the position of the motor vehicle. The environment data relate to stationary objects in an environment of the motor vehicle. The method further includes deriving a visual range from the environment data, and, only if the intention of the driver to overtake has been determined either projecting a warning onto a roadway region in the environment or illuminating an overtaking lane by a headlight of the motor vehicle, depending on the visual range.
US11358521B2 Vehicle wheel units
Systems, methods, tangible non-transitory computer-readable media, and devices associated with the operation of a vehicle are provided. For example, a wheel unit system can receive vehicle data including information associated with states of a vehicle. Further, the vehicle can include wheel wells associated with wheel units that are configured to generate indications associated with the states of the vehicle. The wheel unit system can also determine indications to generate on the wheel units based at least in part on the vehicle data. Furthermore, the wheel unit system can generate the indications on the wheel units. The indications can, for example, include visual indications or auditory indications.
US11358517B2 Light projection device for a moving body having an optical scanner and control portion controlling a mirror portion
A light projection device for a moving body is provided on the moving body and includes: a light source for irradiating light; an optical scanner which has a mirror portion for reflecting the light irradiated from the light source and a drive source for swinging the mirror portion, and scans the light irradiated from the light source; and a control portion which controls to acquire change information of an angle range at which the mirror portion swings, change the angle range at which the mirror portion swings by controlling the drive source based on the acquired change information, and change an irradiation range of the light irradiated from the light source.
US11358500B2 Lateral protecting mechanism and child restraint system therewith
A lateral protecting mechanism includes a fixing base, a protecting block, a locking component, a driving component and an operating component. The fixing base is fixedly disposed on a lateral portion of a child carrier. The protecting block includes a pivoting shaft and is pivotally disposed on the fixing base by the pivoting shaft. The locking component is slidably disposed inside the fixing base. The driving component is disposed inside the fixing base. The operating component is coupled to the driving component. The operating component drives the driving component to drive the locking component to protrude out of the fixing base to abut against the protecting block for restraining a pivoting movement of the protecting block when the operating component is operated.
US11358499B2 Lower and upper latch anchor use detection sensing device
A child restraint seat sensing device for a vehicle including a structural element at least partially defining a volume, wherein the structural element is located in a vehicle passenger seat between a seat base and seat back or is located behind the vehicle passenger seat, a stationary anchor in the vehicle, wherein the stationary anchor is located within the volume defined by the structural element, and a sensor mounted to the structural element, wherein the sensor is configured to detect whether a child restraint seat connector is attached to the stationary anchor.
US11358497B2 Track system having a rolling member
A support member may be configured for selective connection with and removal from track assemblies. A support member may include a body and a rolling member rotatably connected to the body to facilitate movement of the support member along a track. The rolling member may include a grooved configuration to limit movement of the support member relative to said track in a Y-direction. The rolling member may include a groove configured to engage a protrusion or ridge of said track. The rolling member may include a first portion and a second portion separated in an axial direction by the groove.
US11358493B2 Fuel cell vehicle thermal management system and method for managing fuel cell thermal loads
The present disclosure provides a method of managing thermal loads in a fuel cell vehicle. The method may comprise heating a fuel cell coolant of a fuel cell coolant loop utilizing waste heat from a fuel cell to form a heated fuel cell coolant, heating a battery coolant of a battery coolant loop utilizing waste heat from a battery to form a heated battery coolant, heating a refrigerant of a battery refrigeration loop by exchanging heat with the heated battery coolant, and superheating the refrigerant of the battery refrigeration loop by exchanging heat with the heated fuel cell coolant.
US11358488B2 Information processing system
An information processing system includes: a first acquisition unit that acquires battery information on a battery of each of one or more vehicles; a second acquisition unit that acquires supply source information on a state of a power supply source; a selection unit that selects a vehicle for providing electric power for the power supply source as a power source out of the one or more vehicles, based on the supply source information and the battery information; and a request unit that requests the vehicle selected as the power source to provide the electric power.
US11358487B2 Method for charging electric consumers
A method for charging electric consumers at an electricity grid with multiple phases may include measuring a phase current of each of the multiple phases of the electricity grid at a balance point. The method may also include determining to which of the multiple phases each electric consumer of the electric consumers is connected for charging via the balance point. Additionally, the method may include holding an unbalanced load of the multiple phases below an unbalanced load threshold value via communicating a power specification to each electric consumer connected for charging.
US11358481B2 Energy consumption predicting device and energy consumption predicting method
An energy consumption predicting device includes: an acquisition unit acquiring a parameter correlated with at least one of a vehicle speed when a vehicle traveled on a route from a first point to a second point on which a vehicle traveling using only a power source consuming an energy source supplied from outside of the vehicle and stored therein is able to travel, a different vehicle speed when a different vehicle traveled on the route, an output of the power source when the vehicle traveled on the route, and an output of a different power source when the different vehicle traveling using only the same type of different power source as the power source traveled on the route; and a calculation unit calculating a predicted consumption of the energy source which is predicted when the vehicle travels on the route from the first point to the second point.
US11358480B2 Vehicle including fuel cell and residual energy discharge method performed in the vehicle
A vehicle having a fuel cell includes a cell stack including a plurality of unit cells stacked on one another, a direct current/direct current (DC/DC) converter configured to convert the level of stack voltage output from the cell stack and including a discharger to remove residual energy thereof, a power distributor configured to distribute the level-converted voltage output from the DC/DC converter or to provide voltage remaining in the cell stack to the discharger to discharge the voltage in response to first control signals, and a controller configured to generate the first control signals depending on whether the vehicle is traveling normally.
US11358478B2 Light electric vehicle with dynamic gear ratio selection feature
The present disclosure describes a system for determining an optimal gear ratio for a light electric vehicle. The optimal gear ratio may be based on an anticipated or current route of an individual riding the light electric vehicle, riding habits of the individual and/or on maintenance status information associated with the light electric vehicle. When the optimal gear ratio is determined, the system provides an indication of the optimal gear ratio to the light electric vehicle.
US11358476B2 Drive device and vehicle
A drive device includes a motor, an inverter, an electric power storage device, and an electronic control unit. The electronic control unit is configured to generate a first pulse width modulation (PWM) signal of the switching elements by comparison of a voltage command of each phase according to a torque command of the motor and a carrier wave voltage, as a first PWM control. The electronic control unit is configured to generate a second PWM signal of the switching elements based on a modulation factor and a voltage phase of a voltage according to the torque command and a pulse count per unit cycle of an electric angle of the motor, as a second pulse width modulation control. The electronic control unit is configured to limit execution of the second PWM control when high controllability of the motor is requested rather than when the high controllability is not requested.
US11358475B2 Magnetic levitation power system
Provided is a magnetic levitation power system. The magnetic levitation power system includes: a magnetic power system disposed on a wheel hub and a driver shaft, where the magnetic power system generates a power capable of enabling a movement of the wheel hub through an interaction of magnetic fields between the wheel hub and the driver shaft; a first magnetic levitation system disposed on the wheel hub and the driver shaft, where the first magnetic levitation system is capable of enabling the wheel hub and the driver shaft to be in a levitation state within a circumferential extent of 360 degrees with the wheel hub being opposite to the driver shaft through the interaction of the magnetic fields between the wheel hub and the driver shaft; and a second magnetic levitation system disposed on the wheel hub and the driver shaft, where the second magnetic levitation system is capable of enabling the wheel hub and the driver shaft to be in a levitation state in a direction of a central axis of the wheel hub through the interaction of the magnetic fields between the wheel hub and the driver shaft. The present invention solves the problems of high hardware costs, low energy utilization rate, environmentally harmful characteristics, etc. of the existing automobile power system.
US11358471B2 Electrical vehicle system
An electrically powered vehicle system includes a DC/DC converter stage with a rectified input terminal which receives a rectified input from an AC power input. The system also includes a vehicle battery which receives power output from the DC/DC converter stage, via a first link between the rectified input terminal and the DC/DC converter stage. A second link is connected to the first link and to a vehicle device.
US11358464B2 Cooling system of electric power system for vehicle
Disclosed is a cooling system for an electric power system for a vehicle capable of selectively cooling a power component used while the vehicle travels or is charged.
US11358462B2 Transmission device for a hybrid vehicle
A torque transmission device for a vehicle includes a torque input element coupled to a crankshaft of a combustion engine, a first torque output element coupled to a first input shaft of a gearbox, a rotating electric machine including a stator and a rotor arranged in the direction of the transmission of torque, between the input element and the first output element, a rotor support radially supporting the rotor of the rotating electric machine, the rotor support selectively connected to the input element by an input clutch, a fixed distributor fastened to the gearbox and supporting the rotor support, a fixed wall including a first radial end fastened to the gearbox, and a second radial end connected to the torque input element, a first rolling member arranged between the rotor support and the fixed distributor, and a second rolling member arranged between the rotor support and the fixed wall.
US11358458B2 Car cover assembly and a method of using the same
A car cover assembly, having a base, a cover body, a cap and a storage body for the cover body; the base is removably mounted onto a car surface; the cap is removably or fixedly connected to the base; the cover body and the storage body are pressed between the base and the cap; the base and the cap clamp and fix the cover body and the storage body; after the cover body is completely folded, it is stored inside the storage body. The car cover assembly can be placed at anywhere on the car for use. A method of using the car cover is also provided.
US11358457B2 Roof arrangement for a vehicle roof and vehicle roof with a roof opening
A roof arrangement for a vehicle roof with a roof opening may have a movable roof element for optionally closing or at least partially opening the roof opening, wherein the roof element is held by a frame; a first strand-like sealing profile; a second strand-like sealing profile which is formed separately from the first sealing profile, wherein the first sealing profile is configured for sealing in relation to the movable roof element and is fastenable to the vehicle roof; and the second sealing profile is fastened to the frame and is configured for sealing in relation to the frame, wherein the second sealing profile has a drip lip which lies against the frame.
US11358452B2 Latch assemblies and rail attachment for a pickup truck tonneau cover
A tonneau system for use with a bed of a pickup truck. The tonneau system includes a tonneau cover and latch assemblies to retain the tonneau cover to the bed of the truck. The cover is moveable between an unfolded positon where the cover encloses the bed and a folded position where the bed is uncovered. The latch assemblies can include latch bases that define discreet mounting positons for a latch handle assembly that employ retention members to retain the latch handle assembly in a particular mounting positon. Another latch assembly includes a latch base having an endless belt to positon the latch handle assembly. A rail attachment is also provided to mount to the bed and provide an anchor point for keep in to tonneau cover engage over the bed.
US11358447B2 Tolerance compensating hinge attachment
A lift gate door having hinges installed for predetermined positioning into a vehicle. And a method of attaching a lift gate door to a vehicle while maintain proper tolerances. A first fixture holds a set of hinges in predetermined locations which correspond to assembly locations on a vehicle body. Hinges are temporarily attached to the fixture corresponding to the proper vehicle location. A second fixture holds the lift gate in a position which is a final installation position for attaching the lift gate to a vehicle. Self-adjusting moveable fastening nuts are provided in a set of holes in a hinge plate fastening area of the lift gate. The first fixture is moved into aligned orientation with the second feature and the hinges are attached to the lift gate with the fastener. The hinge is aligned in the proper installation orientation for maintaining the lift gate to vehicle gap in proper tolerances when the lift gate door with hinges is installed on the final vehicle.
US11358444B2 Door entry sensor
A belt molding and sensor combination for a door of a vehicle may include at least one sensor and a belt molding. The at least one sensor may be configured to emit signals upon the detection of an action intended to cause a door to open or close, and the at least one sensor may present a sensor outer surface. The belt molding may be configured to extend along at least a portion of a length of a door, and include a cap which presents an outer surface. The belt molding may be configured to be mounted on a door. The sensor outer surface may provide an extension of a cap outer surface, such that the sensor outer surface and the cap outer surface combine to provide an uninterrupted outer surface where the sensor outer surface and the cap outer surface abut against one another.
US11358442B2 Roller blind arrangement comprising a corrugated-tube winding shaft
A roller blind arrangement for a motor vehicle, the roller blind arrangement having a roller blind web and a winding shaft onto which the roller blind web can be wound or from which the roller blind web can be unwound and which has a flexible surrounding-tube arrangement penetrated by a vehicle-attached bearing strut and a corrugated tube as a surrounding-tube element, corrugated-tube ribs being formed on the a corrugated tube and being separated from each other by troughs. The corrugated tube is provided with a coupling overmold at each of its two ends, each coupling overmold being connected to a respective bearing bush and having an outer diameter which corresponds to the maximum outer diameter of the corrugated tube.
US11358433B2 Thermal conditioning systems and methods for vehicle regions
Features for a vapor compression system configured to cool and/or cat (i.e. thermally condition) two or more distinct climate controlled vehicle interior components via a common thermal bus are disclosed. Some embodiments employ a single compressor. Some embodiments employ multiple compressors and/or thermal buses, each servicing components located within respective interior thermal zones of a vehicle, for example a front row seat zone, second and/or third row seat zones, and/or an overhead zone and/or a trunk zone.
US11358432B2 Suspension control apparatus
Provided a suspension control apparatus including a vehicle behavior detection unit (acceleration sensors), an electrorheological damper provided between a vehicle body (1) and each wheel (2), and a controller configured to execute control so that a damping force of each electrorheological damper is adjusted based on a detection result obtained by the vehicle behavior detection unit. The controller includes a target voltage value setting unit (damping force command calculation unit) configured to obtain a target voltage value to be applied to an electrode tube based on the detection result obtained by the vehicle behavior detection unit, a temperature estimation unit configured to detect or estimate temperature of ERF, and a target voltage value correction unit (output limiting unit) configured to change the target voltage value so that a piston speed (V) is adjusted based on a value obtained by the temperature estimation unit.
US11358428B2 Active damper upper mount
The active damper upper mount includes an inner member (11, 111) to which an upper end portion of a rod (22, 122) of an active damper (21, 121) is fixed, an intermediate member (12, 112) that surrounds the inner member in a circumferential direction around a rod axis (O1, O2), an outer member (13, 113) that surrounds the intermediate member in the circumferential direction and is attached to a vehicle body side, a first elastic body (14, 114) that is disposed between the inner member and the intermediate member and supports the inner member and the intermediate member so as to be elastically displaceable relative to each other, and a second elastic body (15, 115) that is disposed between the intermediate member and the outer member and supports the intermediate member and the outer member so as to be elastically displaceable relative to each other.
US11358427B2 Suspension for vehicle
A suspension for a vehicle including a strut tube; a strut rod installed so as to be movable in the strut tube; an insulator part through which an upper end of the strut rod is installed, and which includes a lower cup, an insulator body and an upper cup; and a cap member coupled to the upper cup so as to prevent penetration of foreign matters, and having a coupling structure coupled to the upper end of the strut rod. An anti-rotation structure for preventing rotation of the cap member may be provided in the cap member and the upper cup.
US11358424B2 Current sensing electrical converter
An electrical converter assembly includes a sensing device coupled to one or more wires of a towing vehicle. The sensing device is configured to detect the current flow in the one or more wires and generate a signal in response to the current flow. The converter assembly further includes an electrical component in communication with the sensing device. The electrical component may generate a signal to a towed vehicle in response to the current flow detected by the sensing device. The sensing device may be a non-invasive sensing device. The non-invasive sensing device may detect current flow in the one or more wires of the towing vehicle without direct contact with the conducting element of the wires.
US11358421B2 Tire monitoring system having a control unit configured to operate in a power saving mode and a normal mode
A pneumatic tire includes a first tread area portion, an electric power source, a transmission device, an accelerometer, and a control unit configured to operate in a power saving mode and a normal mode. A contact of the first tread area portion with a surface is detected by sensing acceleration of the first tread area portion by the accelerometer. The control unit is configured to switch from the normal mode to the power saving mode after a detection that the first tread area portion is on a contact patch of the tire. The control unit is configured to switch from the power saving mode to the normal mode when a first specified time depending on the rotation speed of the tire has elapsed since the detection that the first tread area portion is on the contact patch. A monitoring method and a system are used with the pneumatic tire.
US11358419B2 Method for detecting wheel units of a vehicle and wheel mounting positions belonging to the wheel units, and a wheel information system
A method for detecting wheel units mounted at wheels of a vehicle and for detecting wheel mounting positions belonging to each of the wheel units is disclosed. The method comprises the steps of: positioning a mobile communication device at a predetermined start position with respect to the vehicle, moving the mobile communication device from the start position along a path around the vehicle, receiving RF signals from the wheel units and measuring the RF signal strengths thereof by the mobile communication device when moving along the path around the vehicle, performing an analysis of variations of the measured RF signal strengths of the received RF signals depending on the position of the mobile communication device along the path, identifying the wheel units and identifying the wheel mounting positions based on a result of the analysis.
US11358413B2 Bias tire
A bias tire includes two or more carcass layers, at least one belt disposed outward from the carcass layers in a tire radial direction, a reinforcing rubber layer disposed between carcass plies included in a carcass layer of the carcass layers. A belt width of a widest belt with the widest width of the belts is 110% or more and 150% or less of a tread developed width, and a position of an upper end portion of the reinforcing rubber layer located outward in the tire radial direction is apart 3 mm or more from an end portion of the widest belt.
US11358410B2 Artwork magnetic hook and loop backdrop
An artistic magnetic or hook and loop backdrop is disclosed which hangs over an artist's easel for display which makes it easier to cleanup! It works differently than other products on the market because it is a light matted-art magnetic display, as opposed to a heavier cloth canvas. Additionally, this product allows for two interior LED strip lights to be placed on the backdrop so that the display tent can be illuminated without the use of bulky lighting. The artist does not need to stack the canvas in bins or boxes with the Artwork Magnetic Backdrop and can instead roll the backdrop up for easy portability. Ideally, there will be small pockets in the backdrop to store magnets so that the artist can easily access them before hanging new projects. Additionally, this product has been used to hang light weight 8×10″, 11×14″, and 20×24″ artwork through windy outdoor shows.
US11358401B2 Post-processing device and printing system
A post-processing device includes a transport path along which a medium printed with liquid ejected by a liquid ejecting portion is transported, an intermediate tray on which the medium is stacked, a first transporting member starting a first transporting operation of transporting the medium upstream in a transport direction after a rear end of the medium passes through the transport path, a rear-end alignment portion that comes into contact with the rear end of the medium transported by the first transporting member and that aligns the medium, a control portion controlling an operation of the first transporting member, and a detection portion detecting a transporting state of the medium in the intermediate tray, in which when the control portion determines, from an output of the detection portion, that the medium reaches the rear-end alignment portion, the control portion regulates the first transporting operation of the first transporting member.
US11358393B2 Liquid ejection apparatus
A liquid ejection apparatus includes a liquid container for containing liquid which has a refilling port for refilling the liquid container with liquid, a contained liquid information memory unit for storing information on the liquid contained in the liquid container, a refilling liquid information memory unit for storing information on the liquid to be supplied for refilling the liquid container, a liquid ejection head for ejecting the liquid supplied from the liquid container and a control unit for controlling operation of the liquid ejection apparatus according to the information stored in the contained liquid information memory unit and the information stored in the refilling liquid information memory unit.
US11358380B2 Methods and apparatus for molding-in gaskets within the grooves of a planar work material
Exemplary embodiments of the present disclosure are directed towards methods and apparatus for molding-in gaskets that serve as light blockers, within the grooves of a moving planar work material. The gaskets comprise of a hot melt adhesive material that is in a molten state above a particular temperature and gets solidified below a particular temperature. Another exemplary embodiment of the present disclosure is directed towards a planar work material having grooves that are filled with molded-in gaskets, wherein the gaskets are made up of a hot melt adhesive material. The gaskets made of the hot melt adhesive material bond securely with the panels because of inherent adhesive properties, and provide structural stability to the light panels. Another exemplary embodiment of the present disclosure is directed towards the use of a hot melt adhesive material as the molding material for molding-in gaskets within the grooves of a planar work material.
US11358379B2 Apparatus and method for making information carrying cards through radiation curing, and resulting products
The disclosure provides a method for forming an information carrying card or a core layer of an information carrying card using a radiation curing, and an apparatus configured to provide such a radiation curing. The method includes providing a carrier layer that defines at least one cavity, providing an inlay layer supporting at least one electronic component, and positioning at least a portion of the inlay layer in the at least one cavity. The method further comprises dispensing a radiation crosslinkable polymer composition over the inlay layer, and irradiating the radiation crosslinkable polymer composition.
US11358375B1 Flexible micrometeoroid shield
A multilayer particle shield for a spacecraft includes an inboard exterior layer configured to be disposed proximal to the spacecraft, an outboard exterior layer configured to be disposed distal from the spacecraft and at least one interior layer disposed between the inboard exterior layer and the outboard exterior layer, wherein the interior layer includes a semi-rigid, porous, compressible spacer.
US11358370B2 Systems and methods for implementing selective electromagnetic energy filtering objects and coatings using selectably transmissive energy scattering layers
A system and method are provided for forming energy filter layers or shutter components, including energy scattering layers that are actively electrically switchable. The energy filters or shutter components are operable between at least a first mode in which the layers, and thus the presentation of the shutter components, appear substantially transparent when viewed from an energy/light incident side, and a second mode in which the layers, and thus the presentation of the energy filters or shutter components, appear opaque to the incident energy impinging on the energy incident side. The differing modes are selectable by electrically energizing, differentially energizing and/or de-energizing electric fields in a vicinity of the energy scattering layers. Refractive indices of transparent particles, and the transparent matrices in which the particles are fixed, are tunable according to the applied electric fields. The energy scattering layers may conceal a sensor such as a camera or photovoltaic cell.
US11358368B2 Container with improved reclosable cover member
A container (10) for consumer goods comprising: an outer housing (12) comprising a box (14) and a lid (16), the lid (16) being hinged to the box (14) along a hinge line extending across a back wall of the outer housing (12); and a package (18) of consumer goods within the box (14). A reclosable sealing cover member(100) occludes an access opening (20) in the package. The reclosable sealing cover member (100) comprises: a base layer (102) comprising a fibrous cellulosic material; a metal-containing layer (104) provided on an outer side of the base layer (102); and a first polymeric layer (106) provided on an inner side of the base layer (102).
US11358365B2 Splicable environmentally-friendly non-PVC advertising cloth made of a woven structure
A splicable environmentally-friendly non-PVC advertising cloth made of a woven structure, wherein the advertising cloth comprising a mesh base layer (40); a first adhesion-promoting structural layer (10), which is a refractory and waterproof layer covering the front surface (43) and the rear surface (44) of the mesh base layer (40); a second adhesion-promoting structural layer (20) coated on the first surface (13) of the first adhesion-promoting structure layer (10); and a third adhesion-promoting structural layer (30) coated on the upper surface (24) of the second adhesion-promoting structure layer (20), therefore, waterproof and ink-absorbing structure arranged on a mesh base (40) layer, and the width of the advertising cloth (50) can be spliced unlimitedly as required by using high frequency splicing, making the environmentally friendly advertising cloth more applicable also improving the overall advertising effect and quality.
US11358364B2 Vehicle interior member
A vehicle interior member includes: a first core material; a first skin forming a first rim part in which at least a part of the peripheral edge part is folded back to the back surface side of the first core material to sandwich a peripheral edge part of the first core material; a second core material; a second skin forming a second rim part in which at least a part of the peripheral edge part is folded back to the back surface side of the second core material to sandwich a peripheral edge part of the second core material; and a stitch part that stitches the first rim part, the peripheral edge part of the first core material sandwiched by the first rim part, the second rim part, and the peripheral edge part of the second core material sandwiched by the second rim part.
US11358363B2 Light-tight shrink wrapping film
The invention relates to a heat-shrinkable film comprising a first polymer ply A comprising at least one dark pigment, a second polymer ply B comprising at least one white pigment, wherein the thickness ratio of the first ply A is in the range of 5:95 to 50:50, the film has a thickness of 20 μm bis 100 μm, the light transmission of the film is not more than 12%, and the film after 15 seconds in a water bath having a temperature of 95° C. exhibits shrinkage in a main shrinking direction in the range of 20% to 85%. The invention further relates to a hose comprising such a heat-shrinkable film and to a process for producing such a heat-shrinkable film.
US11358359B2 Hydraulic machine unit and method for operating such a machine unit
A hydraulic machine unit that can be operated with various working forces, in which working medium is selectively delivered, via a pump-piston accumulator system, to a main cylinder and at least one driving cylinder, wherein at least for one working stroke a pump system of the pump-piston accumulator system is used to provide working medium to a piston accumulator of the pump-piston accumulator system, and then at least for the working stroke at least the main cylinder is charged with a working pressure from the piston accumulator, and wherein at least for a return stroke the at least one driving cylinder is charged with a return stroke pressure from the pump-piston accumulator system, can be of structurally simple configuration if, at reduced working forces, the working pressure is reduced with respect to the piston accumulator pressure prevailing in the piston accumulator.
US11358357B2 Molding element for manufacturing a noise reducing tread
A molding element having a molding surface forming a contact face and a groove forming rib portion forming the groove comprising two opposed rib side faces and a rib top face connecting two rib side faces. The groove forming rib portion provides at least one space opening to at least one of the rib side faces and/or to the rib top face. An insert is received in the space. The insert comprises a cavity for forming a closing device in the groove. The cavity has two opposed cavity faces and opens to at least two faces of the insert corresponding to the faces of the groove forming rib portion. The insert comprises at least one cutting means extending and/or projecting in a direction the groove forming rib portion extends for cutting a material filled in the cavity during demolding.
US11358356B2 Transfer ring with block and rail system
A transfer ring for use in the manufacture of vehicle tires, the transfer ring including a radially expandable and collapsible segmented cylindrical gripping surface defined by a plurality of inwardly facing arcuate surfaces mounted for radial movement toward and away from a central axis of the cylindrical gripping surface, wherein each arcuate surface is mounted to a corresponding set of driven linkages comprising first, second, and third members, each set of driven linkages further including a block-and-rail cam follower secured to at least one of the first, second, and third members and configured to cooperate with the first, second, and third members to limit movement of the arcuate surface to linear movement radially toward and away from the central axis of the cylindrical gripping surface.
US11358354B2 Process for producing plastic lens and apparatus for producing plastic lens
A process for producing a plastic lens includes a step of stirring and mixing a solution including a polymerization reactive compound in a preparation tank; a step of transferring the polymerizable composition obtained in the step from the preparation tank to a lens casting mold; a step of curing the polymerizable composition; and a step of obtaining a plastic lens molded product by separating the obtained resin from the lens casting mold. The step of transferring the polymerizable composition includes a step of re-mixing the polymerizable composition discharged from the preparation tank and injecting the polymerizable composition into the lens casting mold.
US11358350B1 Lightweight sandwich structures and methods of manufacturing the same
A method of forming a sandwich structure including at least partially filling an open volume of an open cellular core with a sacrificial mold material, consolidating the sacrificial mold material to form a sacrificial mold, laying up a composite facesheet on each of at least two surfaces of the open cellular core, co-curing the composite facesheets by applying a consolidation temperature and a compaction pressure to the composite facesheets to form the sandwich structure, and removing the sacrificial mold. The compaction pressure is greater than a compressive strength of the open cellular core and less than a combined compressive strength of the open cellular core and the sacrificial mold.
US11358347B2 Manufacturing fiber-reinforced thermoplastic concentrates
A fully impregnated fiber-reinforced thermoplastic granule includes a fiber core impregnated with a thermoplastic resin and coated with the resin and subsequently polymerized to form a thermoplastic. The granule is formed in a continuous process including a continuous fiber strand being coated and impregnated with a thermoplastic resin, curing the thermoplastic resin, and cutting the fiber and thermoplastic into granules of a desired length. The continuous process results in a uniform, fully impregnated fiber core in the granule which results in a longer reinforcing fiber for added strength in subsequently produced products formed from the granules.
US11358344B2 Induction welding using a heat sink and/or cooling
A heat sink for use in induction welding includes a number of tiles, where the tiles are electrically non-conductive and thermally conductive, a joint flexibly joining the tiles together, and a fluid path formed through the heat sink for communicating a coolant therethrough.
US11358335B2 Cantilevered mask for openings in additively manufactured part
A mask is provided for an additively manufactured part including a plurality of spaced openings in a surface of the part. The mask is made with the part and includes an attachment ligament configured to integrally couple to the part between the openings in a cantilever fashion. First and second cover members include a proximal ends integrally coupled to the attachment ligament and distal ends extending at least partially over a respective portions of the plurality of openings. A detachment member extends from each of the first and second cover members. The attachment ligament is the sole connection to the part. The mask may have an umbrella shape in cross-section.
US11358334B2 Four-dimensional printing method using thermal anisotropy and thermal transformation, and the resulting product
Disclosed are a 4D printing method using thermal anisotropy and thermal transformation, and the resulting product. The method includes (a) artificially planning transverse printing paths and longitudinal printing paths on a specimen to impose a thermal anisotropy to the specimen, (b) sequentially and alternately forming transversely printed layers and longitudinally printed layers on the specimen by printing a thermoplastic polymer in transverse and longitudinal directions to build a 3D printed product, (c) heating the 3D printed product so that the 3D printed product thermally transforms in a specific direction, and (d) controlling heating time to obtain a 4D printed product having a desired final shape which is formed through the transformation of the 3D printed product over the heating time.
US11358333B2 Foldable 3D printer
A foldable 3D printer includes: a main body having an upper surface parallel to the ground; a stage coupled to the upper surface of the main body and adapted to stack a molding material thereon; a nozzle unit spraying the molding material onto the stage; and a bridge assembly adapted to mount the nozzle unit thereon, the bridge assembly being rotatably coupled to the main body to be positioned parallel to the main body when not in use and to be positioned perpendicular to the main body when in use.
US11358331B2 System and head for continuously manufacturing composite structure
A system is disclosed for additively manufacturing a composite structure. The system may include a print head configured to discharge a continuous reinforcement that is at least partially coated in a matrix, and a compactor configured to compact the continuous reinforcement and the matrix. The system may also include a cure enhancer configured to direct a path of cure energy toward the matrix after discharge, wherein the path of cure energy passes through at least a portion of the compactor.
US11358330B2 Filament deposition head and method of depositing filament material for joining workpieces
A fused filament deposition head is employed for depositing filament materials on workpieces to join the workpieces together. The workpieces can be of an automotive application, aerospace application, or something else. The fused filament deposition head, in an example, has a feed end, a dispensing end, and a heater. The feed end introduces more than one filament in the fused filament deposition head, as demanded in the larger application. The dispensing end delivers materials of the filaments to the underlying workpieces. The materials are delivered together. The heater serves to heat the filaments as they travel through the fused filament deposition head. The filaments can include a filament having a core portion of liquid-crystal polymer material.
US11358329B2 Method and device for the additive manufacturing of components
The invention relates to the field of the additive manufacturing of components, which are formed by the direct deposition of a substance, in the form of granules of a metal or non-metal, which passes from a reservoir into a melt bath, produced by the thermal energy of a laser or electron beam, and subsequently crystallizes. The granules enter the melt bath without the intervention of a gas stream, the path and rate of travel of said granules changing while they are in flight under the effect of an electromagnetic field. The granules travel within a chamber, falling into the melt bath from above from a reservoir, from which they are fed at a set speed by the rotation of an adjustable screw feed, and passing through a system of electromagnetic devices, which control the path of the granules by means of electromagnetic fields. The coordinates of this path are tracked by sensors, which transmit a signal to a computer, wherein the flight path of the granules is adjusted by control via the electronic devices and the delivery speed and volume of the substance is adjusted by adjusting the rotation of the screw feed. The invention increases the efficiency of the production cycle, reduces the dimensions of the equipment and increases the accuracy and speed with which material is delivered for the manufacture of a component, while enabling adjustment of the amount, temperature, path and fraction of said material and increasing the strength of the component.
US11358319B2 System and method for state monitoring of linear drives of stretching and/or blow moulding machines
A linear drive for a stretch and/or blow moulding machine has a force sensor for detecting actual force absorption of the linear drive during operation, a storage device in which data for a desired force absorption during operation are stored, and a comparison device for comparing actual force absorption with desired force absorption and a signal emitter for outputting a signal if a previously defined deviation between desired force absorption and actual force absorption is exceeded. Also provided is a method for determining a friction coefficient of a linear drive for a stretching and/or blow moulding machine, by determining a desired force absorption of the linear drive during operation, detecting using a force sensor, actual force absorption of the linear drive during operation, comparing actual force absorption with desired force absorption, and outputting a signal if a previously defined deviation between desired force absorption and actual force absorption is exceeded.
US11358318B2 Component for conveying gases
This invention provides for a component forming a part of a breathing tube, or forming the breathing tube, for example as a part of a breathing circuit for respiratory therapy. The component comprising a tubular body having a foamed wall. The foamed wall can be formed from extrusion of a single extrudate. The foamed wall is of a sufficient minimum optical transparency such that, in use, there is enabled the visual detection of a liquid (or condensate that may have formed) within the tubular body.
US11358316B1 Super smooth manufacturing method for sensor protective cover
A thermal management system that provides metal mold surface temperature control using cyclic process thermodynamics to enhance plastic material flow and curing conditions making it possible to produce resin rich molded plastic surfaces without micro cracks or fissures to which contaminant particles can adhere or to which dirt can attach.
US11358312B2 Method for manufacturing interdental cleaner
To provide method for manufacturing interdental cleaner configured to suppress leakage of elastomer from space for forming slip resistance portion in mold to outside of space in step of filling elastomer into mold. Method for manufacturing interdental cleaner includes first step of molding base portion having handle portion and shaft portion (40) by filling composite material into first mold, and second step of forming cleaning portion and slip resistance portion by filling elastomer into second mold (200) with the base portion situated in second mold (200). In first step, what is molded has handle portion including base (24), recessed portion (26), and bulge portion (28) bulging from surface of the recessed portion (26). In second step, cleaning portion and slip resistance portion are formed by filling elastomer into second space from portion of base portion distant from bulge portion (28) toward shaft portion (40).
US11358311B2 Optical element and method for manufacturing optical element
To provide a method for manufacturing an optical element, which improves the surface precision of the optical surface as well as reducing the birefringence at a low cost. A method for manufacturing an optical element 1090A having optical surfaces 1091 and 1092 and a non-optical surface 1093A that is adjacent to the optical surface 1092 via a ridge by injection molding includes forming the non-optical surface 1093A with a mold surface. The mold surface includes a sink forming area 1095 as a first area having a first surface roughness, and a high transfer area 1094 as a second area having a second surface roughness different from the first surface roughness. The second area is located outside the first area.
US11358307B2 Method for manufacturing a composite component
There is disclosed a method of manufacturing a composite component comprising a main body and an integral flange, the method comprising applying fibre-reinforcement material on a tool having a main body portion and a flange-forming portion to provide a pre-form comprising a body region and a longitudinally adjacent flange region. The pre-form extends generally longitudinally between two longitudinal ends; and a trailing ply of the pre-form extends generally longitudinally between the longitudinal end closest to the flange region and an inner ply end located in the flange region or partway into the body region. Relative movement between the flange-forming portion and the main body portion causes sliding movement between the trailing ply and the flange-forming portion during a flange forming operation, thereby causing a tension force in at least the flange region of the pre-form of during forming of the flange.
US11358306B2 Peeling apparatus
A peeling apparatus includes: an ingot holding unit holding an ingot with an ingot portion corresponding to a wafer being faced up; an ultrasonic wave oscillating unit which has an end face facing the ingot portion corresponding to the wafer and oscillates an ultrasonic wave; a water supplying unit supplying water to an area between the ingot portion corresponding to the wafer and the end face of the ultrasonic wave oscillating unit; and a peeling unit that holds the ingot portion corresponding to the wafer with suction and peels off the wafer from the ingot.
US11358304B2 Systems and methods for curing a precast concrete product
A method of curing a concrete product having a cavity is described and includes positioning the concrete product on a base, sealing an opening to the cavity using a cover plate, introducing carbon dioxide (CO2) gas into the cavity to execute carbonation of the concrete product, and, in response to the concrete product attaining a target specification, unsealing the opening. A system for curing a precast concrete product is also described.
US11358302B1 Mulch coloring
Coloring systems and methods include a conveyor that transports a material. An auger is configured to move a colorant from a reservoir to the conveyor. A grinder receives the material and the colorant from the conveyor and grinds the material and the colorant together to produce a colored material.
US11358300B2 Multifunctional base for power router and other tools
A multifunctional base for a router is provided to allow precise and repeatable cuts through the use of a set of adjustable fences, template guides and bushings. The base has reference surfaces to allow precision cuts at set distances from a fence or template.
US11358297B2 Electric cutting tool with automatic emergency stop
A safety cutting tool includes an electrically conductive cutting member, an electric motor for actuating the cutting member, a gripping handle electrically insulated from the cutting tool, a cutting trigger control that can be actuated by the hand of the user gripping the gripping handle, the cutting trigger control being electrically insulated from the cutting tool, an emergency stop device sensitive to a user coming into contact with the cutting member. The emergency stop device is controlled by a comparator comparing an impedance of a first electric circuit comprising the cutting tool and a second electric circuit used as a reference, the first and second circuits having manual contact electrodes provided on at least one of the gripping handle of the tool and the cutting trigger control. A method for controlling such a tool is also disclosed. The tool and method are is-applicable to electric secateurs and shears.
US11358296B2 Method of slicing a food item and slicing mechanism employing a gripping element that generates a vacuum grip
A method of processing a food item that includes moving a food item along a direction towards an automated slicer, wherein prior to the food item being sliced by the automated slicer the food item that is being moved has a length, L, as measured along the direction. The method further includes determining a thickness, T, of a slice of the food item to be generated by the automated slicer and slicing the food item that has the length, L, by the automated slicer so that a maximum possible number, Nmax, of slices of the food item are generated that have the thickness, T.
US11358295B2 Method for optimizing a shearing bench and associated shearing bench
The invention relates to a method for optimizing a shearing bench for shearing a film having a thickness less than or equal to 10 microns, the shearing bench comprising a plurality of elements, each element being characterized by a plurality of parameters, the collection of parameters forming the parameters of the shearing bench, the plurality of elements comprising at least one blade assembly comprising a blade and a counter-blade collaborating with the blade, a system for progressing the film, and a system for urging the blade and the counter-blade against one another in order to shear the film.
US11358294B2 Razor handle with movable members
A handle for a shaving razor in which the handle comprises a frame and a movable member assembly operably coupled to the frame such that the frame is disposed between the movable member assembly and where the movable member assembly upper and lower portions are configured to move both above and below the frame. The movement can be linear or rotational. The movable member assembly comprises one or more springs.
US11358290B2 Control apparatus, robot system, method for operating control apparatus, and storage medium
A control apparatus, comprising: an image obtaining unit configured to obtain an image in which a control target that a robot controls and a target position to which the control target is to be moved are imaged by an imaging apparatus that is attached to the robot; an axial direction obtainment unit configured to obtain an axial direction of a rotational axis of the control target; a target position detection unit configured to detect the target position in the image; an operation generation unit configured to generate an operation for the control target so that the target position is present in the axial direction and to further generate an operation by which the control target becomes closer to the target position in the axial direction; and a control unit configured to control the control target in accordance with the operation.
US11358289B2 Joint structure of industrial robot
A joint structure of a robot includes a first member, a second member which is rotatably supported around a horizontal rotation axis line with respect to the first member, and an actuator which rotates the second member with respect to the first member, a through-holes, each of which allows a lubrication space in which a lubricant for the actuator is enclosed to connect with an outer space is provided in at least one of the first member and the second member, and more than three of the through-holes are provided at an interval in a circumferential direction centering around the horizontal rotation axis line.
US11358288B2 Soft robotic gripper with hybrid structure and grasping reliability
A robotic end effector and method for use thereof are provided. The robotic end effector can include a rigid base structure (230), a plurality of rigid proximal phalanges (210) connected to the rigid base structure (230), a plurality of rigid distal phalanges (200) connected to the proximal phalanges (210) respectively, and a plurality of bellows (250), wherein one end of a proximal phalange (210) is connected to one end of the base structure (230) by a bellows (250), wherein one end of a distal phalange (200) is connected to a proximal phalange (210) by a bellows (250), and wherein a portion of the base structure (230), each proximal phalange (210), and each distal phalange (200) are covered in silicone rubber. It can achieve a high output force to input pressure ratio, and cost efficiently.
US11358286B2 Robot system and method of operating the same
A robot system includes a user interface configured to receive an operational instruction from an operator, a robot installed in a workspace and configured to perform a series of works including a plurality of processes, a sensor installed in the workspace, a transparent type display unit configured so that the operator is visible of a physical real world and configured to display information detected by the sensor as the image screen, and a control device. The control device displays on the transparent type display unit, when the robot is operated by the user interface, first information that is information detected by the sensor, as the image screen.
US11358284B2 Signing robotic hand assembly apparatuses, systems, and methods
Intelligent robotic hand assembly systems.
US11358283B2 Robot calibration method and robot calibration device
Provided is a robot calibration method for calibrating a position of an arm tip of a robot, the method including measuring a relative positional relationship between a first link and a second link on opposite ends of at least three links which are connected to each other so as to execute collective calibration for at least two joint axes between the at least three links, measuring a relative positional relationship between a base and a link connected to the base to execute independent calibration for a joint axis between the base and the link, or measuring a relative positional relationship between the first link and another link as to execute independent calibration for a joint axis between the first link and the other link, and calibrating the position of the arm tip based on the collective and the independent calibrations.
US11358282B2 System and method for constraint management of one or more robots
Embodiments of the present disclosure are directed towards a robotic system. The system may include a robot configured to receive an initial constrained approach for performing a robot task. The system may further include a graphical user interface in communication with the robot. The graphical user interface may be configured to allow a user to interact with the robot to determine an allowable range of robot poses associated with the robot task. The allowable range of robot poses may include fewer constraints than the initial constrained approach. The allowable range of poses may be based upon, at least in part, one or more degrees of symmetry associated with a workpiece associated with the robot task or an end effector associated with the robot. The system may also include a processor configured to communicate the allowable range of robot poses to the robot.
US11358278B2 Method for collision detection and autonomous system
Provided is a method for detecting an imminent collision between an object and a component of an autonomous system in the real environment including at least one real, decentralized autonomous component, whereby of at least a part of the autonomous system a virtual image is available, emulating at least one aspect of the autonomous system.
US11358275B2 Drive unit for a robot and method for manufacturing the same
A drive unit for joint being arranged between two arm members of a manipulator of a robotic system, the drive unit being intended for the rotatory drive of one arm member in relation to the other arm member, the drive unit having a first drive module, which is to be connected to a first arm member by means of at least one connecting element in a force- and torque-transmitting manner, and having a second drive module, which is to be connected with a second arm member by means of at least one connecting element in a force- and torque-transmitting manner, in which the connecting elements are configured to cooperate with the arm members in radial direction with respect to the rotary axis of the drive unit.
US11358261B2 Apparatus for tightening threaded fasteners
Apparatus for use with a tool assembly in operations of tightening or loosening threaded fasteners about an axis are disclosed, and in one example includes: a lower clamp assembly; an upper clamp assembly; a reaction adaptor assembly; and a spring assembly formed between the upper clamp assembly and the reaction adaptor assembly. Advantageously an operator can tighten or loosen all fasteners without having to change the initial setup of the apparatus. The lower clamp assembly eliminates the need for extra operators and heavy and bulky equipment to hold the apparatus near the fasteners. The upper clamp allows the operator to rotate the apparatus around with ease. The spring assembly stabilizes and eases vertical height adjustment of the apparatus. The reaction adaptor substantially negates reaction turning forces of the tool assembly during the operations. Drive knobs provide easy alignment of and quick and safe mounting of the tool assembly on the fasteners. Bolting operations about an axis are completed faster, cheaper and with little or no risk of operator injury.
US11358256B2 Fixture clamp manifold apparatus and system for using
A clamp and manifold apparatus comprising internal fluid-flow passages and such apparatus in a system. One embodiment of the apparatus of the invention comprises a clamp body; a manifold, an attachment feature for attaching to a fixture system; a clamping surface; at least one fluid flow passage inside the manifold having at least two endpoints; a first port disposed adjacent to the manifold and in fluid communication with one endpoint of the at least one fluid flow passage inside the manifold; and, a second port disposed adjacent to a second surface of the manifold in fluid communication with the second endpoint of the at least one fluid flow passage inside the body. An embodiment of the system of the invention comprises said clamp and manifold; a fixture; a fluid distribution pump; and fluid routing means connecting the fluid distribution pump and the first port of the apparatus of the system.
US11358255B2 Machine vise anti-lift jaws
A machine-tool vise is described that employs an articulated two-piece movable jaw including a jaw nut that engages the lead screw and a jaw bit coupled to the jaw nut through a slanted interface wherein the slanted interface between the nut and the bit is located at the top of the bit to eliminate the secondary effects found in the prior art.
US11358254B2 Abrasive article
Abrasive articles, along with related compositions and methods, are provided. A first aspect relates to an abrasive article comprising a backing and an abrasive layer disposed on a major surface of the backing. The abrasive layer comprises a particulate mixture comprising formed abrasive particles and diluent abrasive particles. Based on the overall weight of the particulate mixture, about 0 wt. % to less than 10 wt. % formed abrasive particles having a substantially monodisperse particle size of from about 80 micrometers to about 120 micrometers; and about greater than 90 wt. % to about 99 wt. % diluent abrasive particles having a median particle size of from about 50 micrometers to about 250 micrometers.
US11358250B2 Spherical lens surface processing method and spherical lens surface processing apparatus with cup-shaped grinding stone
In a spherical lens surface processing method, a lens surface is ground to a spherical surface by forming a contact state in which a rotating cup-shaped grinding stone is placed in contact with the lens surface and a sphere center oscillation state in which the cup-shaped grinding stone oscillates along the lens surface centered on a sphere center. In the sphere center oscillation state, the distance from the center of the sphere center oscillation to the contact point of the cup-shaped grinding stone with the lens surface is set to be the same as the radius of the spherical surface. The oscillation width of the sphere center oscillation is set so that the contact point of the cup-shaped grinding store with the lens surface can move from one peripheral edge of the lens surface past the lens center on the lens surface to the other peripheral edge.
US11358248B1 Multi-tool blade sharpening apparatus
A blade sharpening apparatus for sharpening a serrated blade includes a blade holder configured to securely hold a serrated blade in a position that exposes a toothed edge of the serrated blade. A grinding wheel rotates about a rotational axis and engages teeth spaced along the toothed edge of the serrated blade that is secured in the blade holder. An oscillating mechanism laterally oscillates the blade holder or the grinding wheel relative to the other at an oscillating distance greater than a depth between the teeth on the serrated blade. A linear actuator longitudinally moves the blade holder or the grinding wheel relative to the other and substantially parallel with the rotational axis of the grinding wheel. The linear actuator is operable with the oscillating mechanism to coincide the longitudinal and lateral movement to correspond to the depth and spacing of the teeth disposed along the serrated blade.
US11358245B2 T-slot alignment compensation mounting system
A T-slot mounting and alignment system for non-rigidly mounting a workpiece or fixture to a work-piece positioner table, welding positioner table or machine tool table having one of more T-slots includes a T-dog, a dog nut, at least one bolt, and at least one fastener. The at least one fastener fastens the T-dog to the workpiece or fixture, and a dog stem of the T-dog extends through a guide slot in the workpiece or fixture and into the T-slot in the table. The dog nut mates with the at least one bolt and tightens to engage a distal end of the dog stem, wherein clearance is provided in the assembled structures to prevent the workpiece or fixture from being tightly clamped against the table. Consequently, compensation for misalignments is possible during setup.
US11358240B2 Deposition mask manufacturing method and manufacturing apparatus thereof
A method of manufacturing a deposition mask includes: a splitting process in which a laser beam irradiated from a light source is split into a plurality of laser beams; a scanning process in which the plurality of laser beams are simultaneously scanned onto the mask substrate; and a tuning process in which irradiation states of the plurality of laser beams are finely changed to correspond to shapes of the plurality of pattern holes while the plurality of laser beams are scanned.
US11358237B2 Laser-driven hydrothermal processing
Systems for processing a material by submerging the material in a fluid and directing laser pulses at the fluid and the material for processing the material. An embodiment removes the surface of concrete, brick, or rock or minerals in a relatively gentle, energy-efficient, and controlled manner that also confines the material that is removed.
US11358235B2 Device for welding rod-shaped electrical conductors and sonotrode for such a device
A device for welding rod-shaped electrical conductors and a sonotrode for such includes a compression space for receiving two connection regions of the conductors to be connected, said connection regions extending in a first axial direction (x-axis), the compression space being defined by a working surface of a sonotrode, which transmits ultrasonic vibrations, and a counterface of an anvil at two opposite sides in a second axial direction (z-axis) and by a boundary surface of a slider element, displaceable in the second axial direction (z-axis), and a boundary surface of a boundary element on two opposite sides in a third axial direction (y-axis). In a special contact zone, which is a section of the working surface of the sonotrode and serves to subject at least one connection region to ultrasonic vibrations, the working surface has a surface configuration that differs from a contact zone formed by the remaining working surface.
US11358233B2 Method for generating a toothed workpiece and control program, tools and tooth-cutting machine suitable therefor
The invention relates to a method for generating a workpiece (3) having a second tooth system (2) incorporated into a first tooth system (1) having a specified tooth system geometry, wherein a first generative processing engagement, intersecting the second tooth system in the kinematics of the generating skiving, is made on the workpiece, which is in particular oversized in relation to the specified tooth system geometry, in particular on a transition from the first to the second tooth system, and then a second processing engagement, matching the specified tooth system geometry, in the kinematics of the generating skiving is carried out on the transition and a remaining oversize is in particular removed while doing so. The invention further relates to tools and to tooth-cutting machines suitable therefor.
US11358230B2 End mill and method for manufacturing machined product
An end mill may include a main body having a bar shape extending from a first end to a second end. The main body may include a plurality of cutting edges located at the first end, and a plurality of flutes individually extended from the cutting edges toward the second end. The cutting edges may include a plurality of long cutting edges and a plurality of short cutting edges. The long cutting edges include a first long cutting edge. N1 is the number of the short cutting edges located forwards in a rotation direction with respect to the first long cutting edge. N2 is the number of the short cutting edges located backwards, opposite the rotation direction with respect to the first long cutting edge. And, N1 is different from N2.
US11358229B2 Drill with grooved flute and method of making drill with grooved flute
A drill includes a drill body having a longitudinal axis, a front end, and a frontend portion and at least one flute in the front end portion. A cutting insert is mounted to the drill body in each flute of the at least one flute at the front end of the drill body. The at least one flute includes a plurality of grooves, concave surfaces of adjacent ones of the grooves intersecting to define a ridge separating the grooves.
US11358225B2 Machine tool
Provided is a lathe capable of facilitating replacement of a ball screw. A machine tool comprises a base, a moving unit, a ball screw, a cap, and a supporting unit provided on the base to support the cap. The cap has a body and a flange expanded larger than the body on the outer side thereof with respect to the axis direction. The supporting unit comprises a recess part which receives the body. The recess part is provided with an opening allowing the threaded shaft to pass in a direction perpendicular to the axis direction in the state that the supporting unit is provided on the base. The supporting unit further comprises a positioning part on which an inner surface of the flange abuts in the axis direction in the state that the body is received in the recess part.
US11358221B2 Build part and method of additively manufacturing the build part
A build part has a body that is additively manufactured on a platform. The body is defined by multiple layers of material consecutively stacked along a build axis and fused together. The body defines one or more fluid channels for directing fluid through the body. Each of the one or more fluid channels is oriented such that a centerline of the respective fluid channel is angled no greater than a maximum offset angle relative to the build axis throughout the length of the fluid channel. The maximum offset angle is no greater than 75 degrees.
US11358218B2 Methods of making flux-coated binder and metal-matrix drill bodies of the same
A method of making a flux-coated binder includes treating metal binder slugs to have an adherent surface, adding a flux powder to the treated metal binder slugs, and distributing the flux powder on the adherent surface of the metal binder slugs. A method of making a metal-matrix composite-based drill bit body includes loading a matrix powder into a bit body mold, loading a flux-coated binder into the mold on top of the matrix powder to form a load assembly, and heating the load assembly to allow the binder to infiltrate into the matrix powder.
US11358215B2 Three-dimensional printing system and method of three-dimensional printing
A three-dimensional printing system, the system comprising a build platform and a printhead for depositing a conductive print material at deposition contact points of a build surface on the build platform. A heating system comprises at least one induction coil for preheating the deposition contact points of the build surface.
US11358211B2 Offset collar delivery for swage tools
Systems and methods are provided for fastening via a swage tool. One embodiment is a method for fastening via a swage tool. The method includes steps of selecting a hole located at a part, aligning an axis of a lockbolt collar with a center of the hole, placing the lockbolt collar flush against the part at a first end of the hole, and swaging the lockbolt collar onto a lockbolt that has been driven through the hole. This securely fastens the lockbolt collar to the lockbolt.
US11358209B2 Method for producing hot forged material
Provided is a method for producing a hot forged material capable of preventing the generation of double-barreling shaped forging defects. The method for producing a hot forged material, wherein both an upper die and a lower die are made of Ni-based super heat-resistant alloy and the method comprises a hot forging step of pressing a material for hot forging by the lower die and the upper die in the air to form the hot forged material, the method comprising: a raw material heating step of heating the material for hot forging in a furnace to a heating temperature within a range of 1025 to 1150° C.; a die heating step of heating the upper die and the lower die to a heating temperature within a range of 950 to 1075° C.; and a transferring step of transferring the material for hot forging onto the lower die by a manipulator after the completion of the raw material heating step and the die heating step, wherein a value obtained by subtracting the heating temperature of the upper die and the lower die from the heating temperature of the material for hot forging is 75° C. or more.
US11358205B2 Method for producing an overlapping connection, and body component for a vehicle
The disclosure relates to a method for producing a overlapping connection, in which at least two overlapping components are connected to one another via a folded flange, with a first edge of a first component being folded over a second edge of a second component to form the folded flange, along with a body component that includes such an overlapping connection for a vehicle and a stamping tool for such a body component. According to the disclosure at least one connection region is formed on the folded flange, in which the stamping tool stamps the first component through the second component at least one stamping point, with displaced material of the first component passing into the second component and producing a positive connection.
US11358204B2 Flange forming device and method of forming a flange on a sheet metal part to reduce surface distortion
A method of forming a vehicle panel includes deforming a sheet metal workpiece between stamping tools to form a first and second edges that converge at a corner of the workpiece's main surface. The first edge is defined by a junction of the main surface and a first flange. The second edge is defined the main surface and a second flange. Forming the first and second edges includes deforming the workpiece so that the second flange has a first region bent to a first angle relative to the main surface and an unwinding region bent to an angle that unwinds from the first region as the second flange approaches the corner. The method includes deforming the workpiece between a second set of stamping tools that deform the first flange and the unwinding region of the second flange until the first and second flanges are bent greater than 90°.
US11358198B2 Method for producing spring strut forks
An efficient method for producing spring strut forks for motor vehicles is presented. In each case two spring strut forks are produced from a metallic extruded profile as a starting product. The extruded profile has a central, middle main chamber and four longitudinal chambers which are arranged offset with respect to one another over the circumference of the main chamber. Wall portions of the main chamber which are situated between the longitudinal chambers are removed, and the extruded profile is severed into two semifinished parts. Each semifinished part has one cylinder portion and two oppositely situated arm portions which project relative to the cylinder portions. The semifinished parts are subsequently mechanically machined, and one spring strut fork is produced from each semifinished part.
US11358197B2 Processing of hollow sections
A system and method provide a material with uniform micro-structure. In an embodiment, an equal channel angular extrusion system includes an interior mandrel. The interior mandrel includes an expanding shear material section and a contracting shear material section. In addition, the system includes a material. The material is disposed about a portion of the interior mandrel. Moreover, the system includes a pressure application device. The pressure application device applies pressure to the material to force the material to contact the expanding shear material section to provide an expanded post-shear material section. Pressure from the pressure application device applies pressure to the material to force the expanded post-shear material section to contact the contracting shear material section to provide a contracted shear material section.
US11358194B2 Roll wear dispersion method for rolling stand and rolling system
When an opposite direction shift for obtaining a required equivalent roll crown and a same direction shift for wear dispersion are used in combination, a difference occurs in the roll gap at both edge portions in the width direction of a rolling target material. Therefore, the difference between a work-side screw down position and a drive-side screw down position is changed so that the roll gap difference between both the edge portions in the width direction of the rolling target material is made close to zero. As a result, the distance between the work roll shafts on a work side and a drive side is changed, so that the roll gap difference at both ends in the width direction of the rolling target material approaches zero. Therefore, the wear of the work rolls can be dispersed while maintaining the equivalent roll crown.
US11358193B2 Method for changing the rolls on a rolling mill
Disclosed is a method for changing the rolls on a rolling mill for rolling a metal strip, carried out using a Quarto rolling mill, including lower and upper working and support rolls. The installation includes a system for extracting the working rolls and the support rolls, including: an actuator pushing the rolls out of the roll stand extraction; a coupling head, secured to the actuator, situated in a position of opening of the roll stand, including: a first coupler driving the chock or the end of the lower working roll, on the rolling-mill drive side; a second coupler driving the chock of the lower support roll, on the rolling-mill drive side. The first and second coupler allow successive extractions of the working rolls and then of the support rolls from the roll stand using the actuator of the extraction system. Also disclosed is a related rolling mill installation.
US11358191B2 Device for drying a metal strip
A treatment device for drying a laminated strip includes: lower and upper crosspieces extending transversely to and on either side of the metal strip, the upper crosspiece embedding an upper pressure cylinder with supporting rollers, the lower crosspiece embedding a lower pressure cylinder with the supporting rollers, the actuator and guide enabling the crosspieces to pass from a retracted idle position to a close working position, for which the lower and upper pressure cylinders, arranged on either side of the strip, transversely to the direction of travel, are each intended to be pressure-applied on the strip by the supporting rollers distributed along the length of the pressure cylinder, and along at least two rotating axes parallel to the longitudinal axis of the pressure cylinder. A first compartment supports all the supporting rollers. A second compartment supports the pressure cylinder. Each compartment is a removable element of the crosspiece.
US11358187B2 Vehicle mounted garbage bin cleaning system including deodorizer and dryer
A vehicle mounted garbage bin cleaning system including power takeoff includes a pair of arms configured for lifting a garbage bin, the pair of arms rotatably coupled to a mount on the vehicle, a hopper configured for accepting the garbage bin when the pair of arms lifts the garbage bin into the hopper, at least one spray rod extending upwards from the hopper, said spray rod including a water nozzle, wherein when the pair of arms lifts the garbage bin into the hopper, the spray rod is situated within the garbage bin, a hydraulic pump mechanically coupled with a transmission of the vehicle, such that the transmission drives the hydraulic pump, a pressure washer pump mechanically coupled to the hydraulic pump, the spray rod is fluidically coupled with the pressure washer pump, a dryer system for drying the bin and a deodorizing system for deodorizing the bin.
US11358181B2 Extendable cleaning device for electrical insulators
A cleaning device for high voltage transmission and distribution insulators, featuring orthogonally oriented scrubbing and wiping attachments for the simultaneous cleaning of perpendicular surfaces, which extend to an insulator surface from telescoping support prongs, which are supported by a handle which provides a gripping location for manual operation of the present invention.
US11358180B2 Workpiece collecting point units and methods for supporting the processing of workpieces
A workpiece collecting point unit for a machine tool, in particular for a flatbed machine tool, such as a laser cutting or punching flatbed machine tool, has a placing area for workpieces produced by the machine tool within the framework of a processing plan, a display unit adapted to display information about the workpieces, which are to be further processed and were placed on the placing area, to an operator, and a signal device adapted to output an identification signal indicating to an operator the location of the selected workpiece collecting point unit for placing the workpiece, which is to be further processed, on the placing area. The workpiece collecting point unit can be used inter alia in a process to support a sequence of processing steps for processing workpieces.
US11358176B2 Sorting detection system for detecting passage of an object through one of a plurality of apertures
In order to detect a correct sorting and a correct passing of an object through an assigned opening of a plurality of openings, a sorting detection system for detecting a passage of the object through the opening of the plurality of openings is provided. Each opening is assigned to a container. The containers receive the object; at least a first sensor identifies the object and generates an identification signal. A control unit receives the identification signal of the first sensor and assigns the identified object to a container based on the identification signal. At least one second sensor having a field of view directed towards the openings and includes at least one detection surface. The detection surface is located within the respective container at a predetermined distance from an edge of a respective opening, and an object passing the detection surface triggers a detection signal of the second sensor.
US11358171B2 Coating system and method
An atomizing spray device includes a housing having plural inlets and one or more outlets fluidly coupled with each other by an interior chamber. The inlets include a first inlet shaped to receive a first fluid and a second inlet shaped to receive a slurry of ceramic particles and a second fluid. The interior chamber in the housing is shaped to mix the first fluid received via the first inlet with the slurry received via the second inlet inside the housing to form a mixture in a location between the inlets and the one or more outlets. The interior chamber in the housing also is shaped to direct the mixture formed inside the housing as droplets outside of the housing via the one or more outlets such that, based on a discharged amount of the first fluid in the droplets, the first fluid promotes evaporation of the second fluid as the droplets traverse from the housing toward a surface of a component.
US11358168B2 Coating apparatus
A coating apparatus includes a process chamber, a rotation device, and a rotation holder. The rotation device is disposed in the process chamber. The rotation holder is connected to the rotation device. The rotation holder includes two extension elements, two retaining elements, and two pins. The two extension elements are disposed around a center axis and separated from each other, wherein each of the two extension elements has a side surface. Each of the two retaining elements has a bottom surface, one of the two retaining elements is connected to one of the side surfaces, and the other of the two retaining elements is connected to the other of the side surfaces. One of the two pins is connected to one of the bottom surfaces, and the other of the two pins is connected to the other of the bottom surfaces.
US11358167B2 Reusable pump dispenser
A reusable pump dispenser may simultaneously dispense and cool a product to a user. The product may be dispensed or dosed in predetermined and/or amounts desired by a user. The product may be cooled from an ambient temperature to a product application temperature. A cooling circuit subassembly may control the temperature, viscosity, and additional properties of the product, thereby providing a maximum benefit of the product when applied to the user. The reusable pump dispenser may eliminate microbes from the product and may provide a physical structure that may be held in a user's hand. The reusable pump dispenser may provide a reusable housing that may be easily replaced, refilled, and reused.
US11358164B2 Water outlet mechanism and shower head comprising the water outlet mechanism
The present disclosure discloses a water outlet mechanism and a shower head comprising the water outlet mechanism. The water outlet mechanism comprises an inlet, an air intake chamber, an air intake passage, and a water outlet passage. The water outlet passage is in communication with the air intake chamber, and the air intake chamber is disposed with a wall connected to an entrance of the water outlet passage. The water outlet passage gradually increases in a downward direction, and a plurality of rectifying ribs protrude from an inner wall of the water outlet passage and are arranged in a circumferential direction at intervals. When the water flows through the inlet and enters the air intake chamber, a flowing cross sectional area of the water changes suddenly, an air pressure surrounding the water is less than the external air pressure, and a negative pressure is generated in the air intake chamber.
US11358162B2 Sprinkler head with damper motor
What is disclosed is a sprinkler head having a nozzle configured for spraying a fluid, such as irrigation water, at a distribution disk. The distribution disk is configured to rotate on an upper axle. The upper axle is housed within an upper axle housing. The upper axle housing is configured to rotate about a lower axle. The dual axle provides for two different rotation axles of the distribution disk in operation. Preferably a speed control device can be positioned to control the speed of rotation of one axle or both axles.
US11358157B2 Pressure regulator for inflation systems
A pressure regulator comprises a primary fluid inlet for connection to a source of high pressure fluid, a fluid outlet for connection to a space to receive the high pressure fluid, a convergent-divergent nozzle having an upstream convergent section, a throat and a downstream divergent section, the primary fluid inlet being in fluid communication with the convergent section of the nozzle; and an outlet pipe having an upstream end arranged around but radially spaced from the outlet of the divergent section of the nozzle, the outlet pipe arranged to receive fluid flow from the outlet of the divergent section of the nozzle and conduct the fluid flowing from the nozzle to the fluid outlet.
US11358156B1 Dual connection cyclonic overhead separator
A vacuum cyclonic separator that includes: a main body having a top surface with an air outlet, a bottom perimeter defining a bottom aperture of the main body, at least two downwardly facing air inlets and at least one side wall extending between the top surface and the bottom portion and shaped such that air received within an interior cavity of main body moves in a cyclone and wherein the at least two downwardly facing air inlets are in at least substantially the same plane as the bottom perimeter of the main body; and a dump valve assembly capable of being opened and closed with one hand where the dump valve is engaged with the bottom portion to seal the bottom aperture of the main body.
US11358154B2 System and method for determining dielectrophoresis crossover frequencies
The present invention provides a new method for accurately identifying DEP cross-over frequencies of one or more particles in a sample, and quickly and efficiently conveying that information to assist in the separation, e.g., DEP separation, or analysis of the one of more particles under examination or investigation. The present invention also provides an apparatus and method for monitoring the dielectrophoretic response of one or more particles and determining the DEP cross-over frequency of particles of interest.
US11358152B2 Underground coal separation process adopting water medium
Disclosed is an underground coal preparation process adopting a water medium, comprising: feeding raw coal into a special underground compact jigging machine to discharge overflow clean coal being dewatered through a φ1 mm fixed screen and screened through a φ13 mm classifying screen, and dewatering powder clean coal with a particle size less than 13 mm to obtain powder clean coal and a centrifugate; grading jigging middling coal by means of a φ13 mm classifying screen into block middling coal and powder middling coal, and dewatering the powder middling coal to obtain powder middling coal and a centrifugal liquid; and sending produced coal slime water to a water medium classifying and separation cyclone, and the obtained coarse middling coal slime and coarse clean coal slime respectively passing through a coarse middling and clean coal slime sieve bends, and then being dewatered.
US11358151B2 Feed hopper for a material processing device
A feed hopper for a material processing device, in particular for a crusher (10), having two side walls (21) and a rear wall of the hopper (22), wherein the side walls (21) are directly or indirectly coupled to a machine support (12.1) in a swiveling manner and can be converted from a set-up work position to a folded-down transport position and back, wherein a feed area is formed between the side walls (21), and wherein at least one of the side walls (21) is supported relative to the machine support (12.1) in the set-up work position by a supporting device (30). A support lever (31), which in the work position is supported directly or indirectly in relation to the machine support (12.1) by a detachable form-fit connection, wherein the form-fit connection prevents the side wall (21) from folding down, projects into the feed area in the folded-down transport position. In this way, a space-saving design is also achieved in the folded-down transport position.
US11358149B2 System and method for multi-axis imaging of specimens
A specimen holding and positioning apparatus operable to substantially non-movably maintain a specimen (e.g., an excised tissue specimen) in a fixed or stable orientation with respect to the apparatus during imaging operations (e.g., x-ray imaging), transport (e.g., from a surgery room to a pathologist's laboratory), and the like for use in facilitating accurate detection and diagnosis of cancers and/or other abnormalities of the specimen.
US11358147B2 System and method for isolating and analyzing cells
A system and method for isolating and analyzing single cells, comprising: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.
US11358145B2 Microfluidic cartridge with built-in sampling device
Microfluidic cartridge (10) comprising a sampling device (30) having a sealing ring (32) arranged to form a microfluidic chamber (31) when a support containing a biological sample is brought into contact with the sealing ring, and a microfluidic network device (13) configured to supply reagents to the microfluidic chamber. The sampling device further comprises inlet and outlet distribution networks (33a, 33b) in fluid communication with the microfluidic chamber and a slide holder (35) to guide and position said support containing a biological sample on the sampling device. The microfluidic network device comprises a plurality of reagent inlet channels (18) fluidly connectable to reagent sources, at least one reagent outlet channel (22) fluidly connected to the sampling device inlet distribution network (33a), and a plurality of valves (25) operable to selectively connect the inlet channels to the at least one outlet channel. The sampling device (30) and microfluidic network device (13) are formed on a common microfluidic support (12) as a single part.
US11358142B2 Disposable cartridge for sample fluid analysis
A disposable cartridge may have a fluid analysis chip for receiving a fluid to be analyzed. The fluid analysis chip may be attached to a fluid preparation unit of the disposable cartridge and may include a base layer. The fluid analysis chip may also include a spacer layer disposed over the base layer, the spacer layer including a microchannel formed therein, the microchannel being configured to guide a flow of the fluid to be analyzed within the fluid analysis chip. The fluid analysis chip may also include a cap layer disposed over the spacer layer, the cap layer including an inlet and an outlet for establishing fluid communication with the microchannel included in the spacer layer, and an interface layer disposed over the cap layer, the interface layer being configured to attach the fluid analysis chip to the fluid preparation unit of the disposable cartridge.
US11358140B2 Apparatus for automatic sampling of biological species employing an amplification with a magnetic nanoparticle and propulsion method
An cartridge is combined with a smart device which is capable of communicating with a network to perform a portable, fast, field assay of a small sample biological analyte. A closed microfluidic circuit for mixes the analyte with a buffer with functionalized magnetic beads capable of being specifically combined with the analyte. A detector communicates with the microfluidic circuit in which the mixed analyte, buffer and combined functionalized magnetic beads are sensed. A microcontroller is coupled to detector for controlling the detector and for data processing an output assay signal from the detector. A user interface communicates with the microcontroller for providing user input and for providing user output through the smart device to the network.
US11358139B2 Pinch to open sample collection device
A blood sample collection and/or storage device includes a two-piece housing that encompasses a port at which a fingertip blood sample is collected. After the sample is taken, the two-piece housing is moved to a closed position to protect the sample for storage and optionally process the sample within the housing. The housing may also be opened to access the stored sample for further processing.
US11358138B2 Fluid sample collection device
A blood sample collection and/or storage device includes a two-piece housing that encompasses a port at which a fingertip blood sample is collected. After the sample is taken, the two-piece housing is moved to a closed position to protect the sample for storage and optionally process the sample.
US11358134B2 Heterobimetallic catalysts and site-differentiated ligands for preparation thereof
Phosphine phosphonate and phenoxyphosphine ligands bearing polyethylene glycol (PEG) chains are used as described herein to produce heterobimetallic catalysts. The ligands can be metallated selectively with palladium or nickel and secondary metal ions to provide well-defined heterobimetallic compounds. These heterobimetallic complexes exhibit accelerated reaction rates and greater thermal stability in olefin polymerization compared to other catalysts.
US11358129B2 Process for the production of ethylene glycol and heterogeneous catalyst composition
The invention relates to a process for the production of ethylene glycol including the steps of: (i) reacting, in a reactor, at a temperature in the range from equal to or more than 170° C. to equal to or less than 270° C., at least a portion of a carbohydrate source in the presence of hydrogen, a solvent, a homogeneous catalyst, which homogeneous catalyst contains tungsten, and a heterogeneous catalyst, which heterogeneous catalyst contains one or more transition metals from groups 8, 9 and 10 of the Periodic Table of the Elements, yielding ethylene glycol and a spent heterogeneous catalyst; (ii) regenerating the spent heterogeneous catalyst by removing at least a portion of deposited tungsten species from the spent heterogeneous catalyst, yielding a regenerated heterogeneous catalyst; and (iii) using at least a portion of the regenerated heterogeneous catalyst as heterogeneous catalyst in the reaction of step (i). The invention further relates to a regenerated heterogeneous catalyst composition obtainable therein.
US11358128B2 High activity reforming catalyst formulation and process for low temperature steam reforming of hydrocarbons to produce hydrogen
A method for producing a hydrogen rich gas from a heavy hydrocarbon feed comprising the steps of introducing the hydrocarbon feed to a reactor, the reactor comprising a low temperature reforming catalyst, the low temperature reforming catalyst comprising an amount of praseodymium, 12 wt % nickel, and an aluminum oxide component, contacting the low temperature reforming catalyst with the hydrocarbon feed in the reactor, wherein the reactor operates at a temperature between 500° C. and 600° C., wherein the reactor operates at a pressure between 3 bar and 40 bar, and producing the hydrogen rich gas over the low temperature reforming catalyst, wherein the hydrogen rich gas comprises hydrogen.
US11358127B2 NOx adsorber catalyst
A NOx adsorber catalyst and its use in an emission treatment system for internal combustion engines, is disclosed. The NOx adsorber catalyst composition comprises a support material, one or more platinum group metals disposed on the support material, and a NOx storage material.
US11358122B2 Moisture absorbent pack for vehicle lamp
A moisture absorbent for a vehicle lamp includes a first inorganic material, a second inorganic material, alkali metal phosphate, and a polymer wax are included. A composite moisture absorbent structure includes a first moisture absorbent pack including a powder type moisture absorbent and a second moisture absorbent pack including a capsule type moisture absorbent are embedded.
US11358119B2 Carbon micro-plant
The present disclosure provides biorefining systems for co-producing activated carbon along with primary products. A host plant converts a feedstock comprising biomass into primary products and carbon-containing co-products; a modular reactor system pyrolyzes and activates the co-products, to generate activated carbon and pyrolysis off-gas; and an oxidation unit oxidizes the pyrolysis off-gas, generating CO2, H2O, and energy. The energy is recycled and utilized in the host plant, and the CO2 and H2O may be recycled to the reactor system as an activation agent. The host plant may be a saw mill, a pulp and paper plant, a corn wet or dry mill, a sugar production facility, or a food or beverage plant, for example. In some embodiments, the activated carbon is utilized at the host plant to purify one or more primary products, to purify water, to treat a liquid waste stream, and/or to treat a vapor waste stream.
US11358117B2 Methods for solidification and stabilization of industrial byproducts
An agglomerate is provided that can include an aluminosilicate (ash) base material and one or more of a binding agent or leach reduction agent. Each of the agglomerate and binding agent can include no more than about 25 wt. % cement.
US11358113B2 Non-thermal micro-plasma conversion of hydrocarbons
Embodiments relate to generating non-thermal plasma to selectively convert a precursor to a product. More specifically, plasma forming material, a precursor material, and a plasma promoter material are provided to a reaction zone of a vessel. The reaction zone is exposed to microwave radiation, including exposing the plasma forming material, the precursor material, and the plasma promoter material to the microwave radiation. The exposure of the plasma forming material and the plasma promoter material to the microwave radiation selectively converts the plasma forming material to a micro-plasma. The precursor material is mixed with the plasma forming material and the precursor material is exposed to the micro-plasma. The exposure of the precursor material to the micro-plasma and the microwave radiation selectively converts the precursor material to a product.
US11358110B2 Internal, fluidized bed reaction apparatus, and method for manufacturing trifluoromethyl pyridine-based compound
An aspect of the present invention provides an internal and the like. The internal is easily handled and is capable of yielding a satisfactory defoaming effect. An internal (50) is used in a fluidized bed reaction device (1), in which a first material and a second material are brought into contact with each other and reacted with each other. The internal (50) is attached to a ceiling part of the fluidized bed reaction device (1), and includes a plurality of chains (21).
US11358108B2 Inner core assembly and vibration mixer
An inner core assembly for a vibration mixer, includes a motor assembly and a compression assembly located above the motor assembly, wherein the motor assembly comprises a vibration motor, a rotor shaft of the vibration motor is connected to the compression assembly by using an eccentric structure, the compression assembly comprises a stage, the stage is connected to a pressure plate mounting bracket by using a guiding shaft, the pressure plate mounting bracket is capable of sliding along the guiding shaft, the rotor shaft of the vibration motor rotates and drives, by using the eccentric structure, the compression assembly to perform reciprocating motion.
US11358102B2 Agarose ultrafiltration membrane composites for size based separations
The embodiments described herein relate to agarose ultrafiltration membrane composites and methods for making and using the same.
US11358100B2 Arrangement for providing sterile water for injection purposes
An arrangement for providing sterile water for injection purposes is described. A device for heating drinking water above the boiling point, a device for maintaining a chamber inner pressure which lies below the atmospheric pressure, and an electronic controller are provided, and the chamber is equipped with at least one membrane which is impermeable for liquids and a film or plate at a distance from the membrane, wherein steam which is permeated through the membrane is condensed on the film of plate. The membrane and the film or plate form a module, and the condensed water can be removed from the chamber via an outlet as sterile water for injection purposes.
US11358099B2 Reduced-pressure medical systems and methods employing a moisture processing device
Systems, methods, and devices related to removing fluids from a patient are provided. In one instance, fluid is removed from the patient and delivered to a canister using reduced pressure. Reduced pressure is supplied to the canister via a reduced-pressure delivery conduit that includes a moisture processing device and a hydrophobic filter. The moisture processing device condenses moisture from the air to prevent condensation from occluding the hydrophobic filter. The moisture processing devices includes an expanded volume and one or more liquid-impermeable, vapor-permeable membranes. The liquid-impermeable, vapor-permeable membrane allows vapor to egress the moisture processing device. Other systems, methods, and devices are presented.
US11358095B2 Electrochemical reactor
An electrochemical reactor is arranged inside an exhaust passage of an internal combustion engine and is provided with a plurality of groups of cells. Each group of cell has a plurality of cells, each cell has an ion conducting solid electrolyte layer, and an anode layer and cathode layer arranged on a surface of the solid electrolyte layer. Each group of cells is configured so that all of the exhaust gas flows into passages defined by cells configuring the group of cells and so that both of the anode layers and the cathode layers are exposed to each passage. The plurality of groups of cells are arranged aligned in a direction of flow of exhaust gas and different groups of cells are connected to a power source in parallel with each other.
US11358087B2 Multiple bead air filter seal
The present disclosure provides one filter with multiple standing compression seals that work together to seal against the mating filter housing assembly. The first compression bead design enables the second bead to seal against the Housing surface for maximum sealing performance for preventing unfiltered fluid from passing through a filter housing assembly.
US11358086B2 State estimation apparatus, method, and program storage medium
A state estimation apparatus includes: a current information acquisition part that acquires information about a current at a power supply part of a refrigerating/freezing apparatus; a current information storage part that holds current information in a normal state of the refrigerating/freezing apparatus; an evaluation part that derives a degree of change based on the acquired current information and the current information in the normal state of the refrigerating/freezing apparatus; a filter cleaning determination part that estimates a clogging state of a filter of the refrigerating/freezing apparatus based on the degree of change to determine whether cleaning of the filter is necessary; and an output part that provides, for a determination result indicating that the cleaning of the filter is necessary, an output to that effect.
US11358085B2 Device and method for detecting filter clogging
The present disclosure relates to a device and to a method for detecting filter soiling of a filter system having at least an air filter installed in an air duct and an electrically controlled fan for producing an air flow in the air duct, wherein the device comprises at least a motor controller for controlling the fan motor by means of PWM control and an evaluating apparatus for determining the actual rotational speed (ni) of the fan in accordance with the actual degree of modulation (Ti) of the motor current for achieving the present rotational speed (ni), wherein, in the evaluating apparatus, setpoint value pairs (nsetpoint, Tsetpoint) for the setpoint rotational speed (nsetpoint) at a certain degree of modulation (Tsetpoint) are also stored, as well as a comparator in order to compare the actual value pairs (ni, Ti) with the setpoint value pairs (nsetpoint, Tsetpoint) and to obtain the degree of filter soiling of the air filter therefrom.
US11358079B2 Fluid system with filter differential pressure control
A fluid system includes a fluid valve, a fluid filter connected to the fluid valve, a first pressure sensor in fluid communication the fluid filter, a second pressure sensor disposed downstream of the fluid filter, and a controller configured to determine a condition of the fluid filter according to information from the first pressure sensor and the second pressure sensor. The controller may be configured to control operation of the fluid valve according to the condition of the fluid filter and the information from the first pressure sensor and the second pressure sensor. Methods for controlling a fluid system are also disclosed.
US11358078B2 Conductive thread for vehicle maintenance
A filter includes filter medium that screens out impurities from a fluid, and a conductive thread contacting the filter medium. A power source provides electric current flowing through the conductive thread, which causes electrical phenomena that is detected by a sensor. A sensor detects the electrical phenomena resulting from the flow of electric current through the conductive thread. Buildup on impurities in the filter causes a change in the electrical phenomena, which change is detected by the sensor and indicates the level of impurities in the filter. An indicator is in communication with the sensor, and provides an alert that the filter should be replaced when the level of impurities exceeds a predetermined threshold.
US11358074B2 Spin plate cyclonic filter
A spin filter plate is disclosed. The spin filter may be mounted in any type of separator/filter system used in irrigation system. The spin filter plate enables to create a cyclonic flow of the fluid, independent of the angle the fluid is supplied to the filter system.
US11358063B2 Generation of audience appropriate content
Multimedia content to be played on a multimedia player device can be received. Whether the multimedia content contains audience-inappropriate content can be determined. Replacement content corresponding to the audience-inappropriate content can be generated. The generated replacement content can be caused to play on the multimedia player device in lieu of the audience-inappropriate content.
US11358062B2 Systems and methods for providing recommendations to improve gameplay
Systems and methods are described for recommending a proposed hardware configuration to a first user in response to determining that a performance aspect of the first user having a first hardware configuration playing a multiplayer game is worse than a performance aspect of a second user having a second hardware configuration jointly playing the multiplayer game. The proposed hardware configuration is generated based on the first hardware configuration and the second hardware configuration and caused to be displayed on a device of the first user.
US11358060B2 Fantasy sports data analysis for game structure development
In an aspect, fantasy sports data is analyzed to generate and/or manage the delivery of and user experience of fantasy sports games and contests, including timing and payout structure(s) for short-term fantasy contests, such as daily, weekly, etc. fantasy sports contests, that motivate and appeal to contestants and is/are reasonably structured and concisely represented. In yet another aspect, a daily fantasy contest system is provided to automatically adjust to user demand without overshooting profitable levels and offer a variety of different contests, as well as offer contests with guaranteed and non-guaranteed payouts.
US11358049B2 Electric balance car
An electrical balance car comprises pedals. Each pedal has a convex part located on the edge, and a concave part located in the middle and used to restore the pedal after the pedal descends under the effect of acting force. The electrical balance car can be controlled steadily and is ingenious in structure, easy to assemble and durable.
US11358048B2 Rotation mechanism for electric balance car and electric balance car comprising rotation mechanism
Disclosed is a rotation mechanism (4) for an electric balance car. The rotation mechanism connects a left car body and a right car body of the electric balance car, and comprises a rotary shaft (40), a sleeve ring (41) and a bearing (42), wherein the sleeve ring (41) is fixedly connected to one side of the rotary shaft (40), the bearing (42) is sheathed on the other side of the rotary shaft (40), and a limiting part (411) is protruded outwardly at a position of an outer edge of the sleeve ring (41). Also disclosed is an electric balance car, comprising the rotation mechanism (4). The rotation mechanism of the electric balance car has a firm and reliable structure, operates smoothly, is convenient to install, and is durable.
US11358044B2 Upper body rotational assistive device
A rotational assistive device includes a first end portion configured for operable connection with a user, and a second end portion configured for operable connection with an implement utilized via a swinging motion. A main body portion extends between the first end portion and the second end portion. The main body portion includes a plurality of telescoping leg portions, such that when the implement and rotational assistive device are swung, the main body portion moves between a closed position having a closed length and an extended position having an extended length greater than the closed length.
US11358042B2 Rideable golf bag cart/cycle
A rideable golf bag cart/cycle (10) is a personal riding golf cart/cycle adapted to transport a single rider (13) and a golf bag (12) for use on a golf course. The cart/cycle (10) is generally symmetrical about a longitudinal plane (16) and includes a frame (18) with a seat (20), a front wheel and steering components (22), a rear wheel (24), an inclined bag support structure (26) extending between the legs of the rider (13), and a motor/control subassembly (28). A collapsed mode (30) in some embodiments is achieved by folding down the handlebars (72) and pivoting the running boards (56) up against the frame (16). An enhanced embodiment (118) includes a canopy (122) and a deluxe multifunctional console (124).
US11358040B2 Golf club head with adjustable sole weight
A golf club head with an adjustable weight assembly that includes a pair of stacked, rotatable circular plates with through-slots and a slidable weight that can move within the slots and clamp the plates together so that they are reversibly fixed to a body portion is disclosed herein. The plates are preferably composed of a lightweight material such as composite, and are located on the sole so that the weight assembly is visible to a user. The plate and slidable weight combination and allows for an increased range of personal performance customization by way of adjustability and interchangeability without using up available discretionary mass in the golf club head.
US11358033B2 Golf ball
An object of the present invention is to provide a golf ball having excellent durability. The present invention provides a golf ball comprising a core and at least one cover layer covering the core, wherein the core is formed from a core rubber composition containing (a) a base rubber, (b) an α,β-unsaturated carboxylic acid having 3 to 8 carbon atoms and/or a metal salt thereof as a co-crosslinking agent, (c) a crosslinking initiator, and (d) a hindered phenol compound, and (b) the co-crosslinking agent and (d) the hindered phenol compound are blended in the core rubber composition such that the following expression (1) is satisfied: 0.04≤HF/B≤0.35  (1) in the formula (1), HF=a number of OH functional group in one molecule of (d) the hindered phenol compound×an amount of (d) the hindered phenol compound (mole) with respect to 100 parts by mass of (a) the base rubber, and B=an amount of (b) the co-crosslinking agent (mole) with respect to 100 parts by mass of (a) the base rubber.
US11358031B2 Safety device for assisting a user to traverse a structure
A system assists a user to traverse a structure. A safety device includes a sensor assembly to detect positions of a user along a travel path for a structure, wherein the travel path includes a plurality of attachment points to secure the user to the structure via one or more lines, a motion assembly to move the safety device along the travel path based on the detected positions of the user, wherein the motion assembly maintains a threshold distance from the user, and a coupling mechanism to couple the one or more lines to one or more of the attachment points encountered along the travel path. Embodiments of the present invention further include a method and program product for assisting a user to traverse a structure in substantially the same manner described above.
US11358030B2 Exercise machine and cross trainer
The present invention is directed, in part, to a system and methods for combining newly designed cardiovascular equipment with the added features of an upper body weight training regimen in order to provide a user a full body workout, cardiovascular exercise and weight training simultaneously. The invention does so by employing either a weight tray apparatus configured to newly designed cardiovascular equipment or machine or through the use of an adjustable weight training apparatus combined with the newly designed cardiovascular equipment or machine. More specifically, the present invention relates to a system and methods for combining newly designed cardiovascular equipment including stationary and recumbent bikes, elliptical machines, treadmills and stair steppers, with a tray apparatus that allows a user to employ free weights. The invention further relates to a system and methods for combining newly designed cardiovascular equipment including stationary and recumbent bikes, elliptical machines, treadmills and stair steppers that are configured with an adjustable weight training apparatus that allows a user to build upper body muscle groups simultaneously with cardiovascular exercise, in effect, providing a full body workout.
US11358027B2 Training instrument and input device
A non-limiting example training instrument comprises a hollow main body formed of an aluminum alloy. The main body is constituted by two gripping portions opposite to each other with a space therebetween and a coupling portion coupling the two gripping portions. A load sensor is arranged in the coupling portion inside the main body. The load sensor is a load cell, a strain gauge affixed to an interior of the main body, and a part of the main body to which the strain gauge is affixed functions as a strain body. Therefore, if a user applies a force so as to bring the two gripping portions close to each other or a force so as to move the two gripping portions away from each other, a load thereof is detected by the load sensor.
US11358025B2 Torque overdrive stair climber
Disclosed herein is a stair climber that includes a frame having a base, an upper axle and a lower axle, and steps revolvably coupled to the upper axle and the lower axle. The stair climber also includes an electric brake mechanism operating in generative mode and coupled with the steps and configured to provide a variable resistive force. Also included is a controller that receives an indication of a selected exercise mode from a user that includes a first speed, a second speed, and a difficulty level. The controller also balances a load, in a learning mode, on the steps based a user's weight at the first speed, and controls, in response to the user applying an additional load to the steps via a rail system, the electric brake mechanism to apply the difficulty level of the selected exercise mode and prevent the steps from exceeding the second speed.
US11358022B2 Method and apparatus for bi-directional ankle exercise
Apparatus for bi-directional ankle exercise movements has a main frame with a seat and upwardly extending columns at either side to support a “U” shaped sub-frame, mounted so that it pivots about a horizontal axis passing very nearly through the ankles of a seated user and interconnecting linkages simultaneously enforcing ankle inversion, with plantarflexion and then ankle aversion, with dorsiflexion, about perpendicularly intersecting axes, while resisting such movements, so as to provide bidirectional ankle exercises according to a progressive resistance program, thus strengthening the ankle muscle groups for enhanced balance and dynamic stability.
US11358021B2 Foot slip for securement of exercise bands
The present invention relates to an exercise aid device which is placed over top of a user's foot. The exercise aid device has a base, a raised backing, and two sidewalls positioned about opposing sides of one another. The two sidewalk extend towards one another at the front end of the base, forming a band which provides for a first opening. A foot may be placed through the first opening, and held securely in place by the combination of the band and the raised backing. An exercise band may be looped through an opening which extends from one sidewall to the opposing sidewall and through the base, or may be affixed to the device by a securement placed on the exterior of the device to attach resistance cables such that the exercise aid device serves as an anchoring unit during exercise routines.
US11358020B2 Barbell
A barbell including a bar member, a first side weight assembly and a second side weight assembly. The bar member has a first side sleeve region and a second side sleeve region opposite the first side sleeve region. The first side weight assembly includes a weight surface and extends over the first side sleeve region, and is rotatively coupled to the bar member through an inner and outer slidable engagement surface. The second side weight assembly includes a weight surface and extends over the second side sleeve region, and is rotatively coupled to the bar member through an inner and outer slidable engagement surface. The bar member includes a first and second surface enhanced region, the first surface enhanced region spanning a portion of the central region and the first side sleeve region, and with the second surface enhanced region spanning a portion of the central region and the second side sleeve region.
US11358013B2 Pathogen-killing filter assemblage
A filter configured for capturing and killing pathogens, the filter including a first breathable layer including copper; and a second breathable layer including silver, the second breathable layer coupled to the first breathable layer, wherein the first breathable layer and the second breathable layer cooperate to capture and kill pathogens mobilized through at least one of the first breathable layer and the second breathable layer.
US11358006B2 Radiation therapy system with follow-the-lights user interface
Example methods and apparatuses of controlling a user interface with a plurality of input mechanisms are disclosed. One example method includes causing a first set of input mechanisms in the plurality of input mechanisms to be visually emphasized via a first visual technique while a second set of input mechanisms in the plurality of input mechanisms is not visually emphasized via the first visual technique, receiving a user input via an input mechanism that is included in the first set, based on the user input, determining a third set of input mechanisms in the plurality of input mechanisms and a fourth set of input mechanisms in the plurality of input mechanisms, and causing the third set of input mechanisms to be visually emphasized via the first visual technique while the fourth set of available input mechanisms is not visually emphasized via the first visual technique.
US11358005B2 Offline angle selection in rotational imaging and tracking systems
A processing device determines a plurality of angles from which tracking images can be generated by an imaging device. The processing device generates a plurality of projections of a treatment planning image of a patient, the treatment planning image comprising a delineated target, wherein each projection of the plurality of projections has an angle that corresponds to one of the plurality of angles from which the tracking images can be taken. The processing device determines, for each angle of the plurality of angles, a value of a tracking quality metric for tracking the target based on an analysis of a projection generated at that angle. The processing device selects a subset of the plurality of angles that have a tracking quality metric value that satisfies a tracking quality metric criterion.
US11358002B2 Method and apparatus for non-thermal nail, foot, and hand fungus treatment
A method and device for treating an infection of the nail or nail bed and adjacent tissues through non-thermal means is described. The device illuminates an area with light in the near-infrared region of the electromagnetic spectrum. Preferably, light having wavelengths of from about 870 nm to about 930 nm will be used. Further, the device includes light emitting diodes that are capable of emitting ultraviolet light. These lights are intended to provide a sterile environment for a user using the device.
US11357999B2 Electronic device
An aspect of the present disclosure relates to an electronic device, and more particularly, to an electronic device that may include: a substrate; a plurality of light emitting devices, disposed on the substrate; a wavelength converting layer, disposed on the substrate, wherein the plurality of the light emitting devices emit a light of same color, wherein light emitted from the light emitting devices is converted by going through the wavelength converting layer, wherein the converted light is extracted to outside of the electronic device, and has a wavelength longer than that of the light emitted from the light emitting devices. Through this, an electronic device can be provided emitting light having a wavelength from which effects of inflammation treatments and skin regeneration can be acquired.
US11357997B2 Equipment and methodolgies for non-invasive treatment for addiction
Methodologies and mechanisms are provided for introducing one or more magnetizable particles introduced non-invasively into one or more body structures containing nervous tissue in a subject, directing, guiding, transporting, focusing and/or concentrating the one or more particles using at least one image-guidance component in proximity to the one or more body structures which can direct the one or more particles within the one or more body structures, and modulating, using at least one activation component, the one or more particles to modulate neuronal function in the one or more body structures of the subject.
US11357996B2 System and method for extra cardiac defibrillation
A system and method for extra cardiac defibrillation is disclosed. In a particular embodiment, an extra cardiac implantable cardioverter defibrillator system includes an implantable defibrillator having a metal case and a defibrillation lead. The defibrillation lead has a connector at its proximal end for coupling to the implantable defibrillator and a first defibrillation coil electrode at a distal portion of the lead. The first defibrillation electrode configured to be disposed in an inferior vena cava.
US11357995B2 Implantable head located radiofrequency coupled neurostimulation system for head pain
A system is provided for driving an implantable neurostimulator lead, the lead having an associated plurality of electrodes disposed in at least one array on the lead. The system comprises an implantable pulse generator (IPG), the IPG including an electrode driver, a load system for determining load requirements, an IPG power coupler, and an IPG communication system. The system also includes an external unit, which includes an external variable power generator, an external power coupler, an external communication system, and a controller for varying the power level of the variable power generator.
US11357994B2 Autonomous cardiac implant of the leadless capsule type, including a piezoelectric beam energy harvester
An energy harvester includes a pendular unit subjected with a piezoelectric beam coupled to an inertial mass. On the clamped side of the beam, a beam frame includes two pressing elements between which the beam is taken in sandwich, each including i) an intermediate part, an internal face of which presses on a corresponding face of the beam, and ii) a pressure plate, an internal face of which presses on an external face of the intermediate part, a printed circuit board being interposed between them. The intermediate parts and the pressure plates are passed through by at least one common transverse bore receiving a locking pin. The intermediate parts, the pressure plates and the pin are each massive metal parts ensuring a direct electrical and mechanical contact with the electrodes of the beam and with the printed circuit boards.
US11357991B2 Medical element insertion position indicator
An electronic medical device includes a first portion, with the first portion including a first insertion hole and an external surface. The first insertion hole is to removably receive an elongate element. The external surface of the first portion comprises a first position indicator, which is located to be visibly juxtaposed relative to a first operative element of the elongate element when the elongate element is fully inserted in the first insertion hole. In some instances, the position indicator may serve a dual function as a vent.
US11357990B2 Method for programming an implantable medical device and system for configuring stimulation parameters of an implantable medical device
A method programs an implantable medical device to configure the implantable medical device for stimulating neural tissue by at least one electrode. The method includes: performing, by the implantable medical device, an evoked compound action potential (eCAP) threshold search by stimulating the neural tissue with test stimulation pulses; determining, based on the eCAP threshold search, an eCAP threshold amplitude and a coupling factor that is indicative of a coupling between the at least one electrode and the neural tissue; and generating a first set of stimulation parameters containing at least a stimulation amplitude that is determined in dependence on the eCAP threshold amplitude and the coupling factor.
US11357989B2 Pacemaker lead for cerclage pacing
A pacemaker lead for cerclage pacing includes a lead fixing part including a fixing tip whose diameter becomes gradually smaller toward an end of a distal part thereof, a plurality of bipolar electrodes that come into close contact with heart muscle, in an outer circumference of the lead fixing part, and a guide wire insertion through hole through which a guide wire can be inserted thereinto, a lead body part configured to be extended to the lead fixing part, having a stylet insertion through hole formed therein, and a body fixing part formed in a bent shape so as to be fixed to an inner wall of the coronary sinus, and a stylet inserted into the stylet insertion through hole, enabling the pacemaker lead for cerclage pacing to be easily moved within the body of the patient.
US11357985B2 Transvascular diaphragm pacing systems and methods of use
Transvascular diaphragm pacing systems (TDPS) and methods are disclosed for providing respiratory therapy to a patient. The TDPS can provide rapid insertion and deployment of endovascular pacing electrodes in critically ill patients who require intubation and invasive PPMV in order to support the physiological requirements of the human ventilatory system. The systems and methods make best use of the contractile properties of the diaphragm muscle and prevent muscle disuse and muscle atrophy. This can be carried out by engaging the phrenic nerves using patterned functional electrical stimulation applied to endovascular electrodes that are temporarily and reversibly inserted in central veins of the patient, such as the left subclavian vein and the superior vena cava. The TDPS can be designed to seamlessly interface with any commercially available positive-pressure ventilatory assistance/support equipment such as is commonly in use in hospital intensive care units (ICU) for treating critically ill patients with breathing insufficiencies, pain, trauma, sepsis or neurological diseases or deficits.
US11357980B2 Apparatus for applying an electrical signal to a subject
Apparatus and methods are described including placing a set of two or more electrodes (22) in electrical contact with a portion of a subject's body. At least one computer processor (24) drives the electrodes to apply an amplitude shift keying signal to the portion of the subject's body, the amplitude shift keying signal containing a high frequency component that acts as a carrier wave, the high frequency component having a frequency of between 80 Hz and 120 Hz, and a low frequency component that acts as a modulating component that modulates the carrier wave, the low frequency component having a frequency of between 1 Hz and 8 Hz. Other applications are also described.
US11357979B2 Systems and methods for sensing and stimulation
A system for stimulating body tissue may include a stimulation lead, sensors, and a control unit. The stimulation lead may include one or more energy sources. The control unit may include a processor and non-transitory computer readable medium, and an interface (e.g., touch screen interface) for receiving user inputs and communicating information to the user. The sensors may be configured to provide impedance measurements to the control unit. The control unit may calculate lung gas distributions and/or generate an image modeling lung gas distributions. Stimulation delivered by the stimulation may be adjusted based on the impedance measurements.
US11357977B2 Expanding coil coupling for lead extension and extraction
A device for extending a lead according to some embodiments includes a body, a tubular member coupled to the body, the tubular member comprising an outer surface, wherein the outer surface is sized to insert into an inner lumen of a lead, the tubular member is movable between a first configuration in which the tubular member slides into the lead, and a second configuration in which at least a portion of the tubular member expands to engage an inner surface of the lead; and, an actuation mechanism operatively coupled to the tubular member, the actuation mechanism configured to move the tubular member between the first configuration and second configuration.
US11357972B2 System and method for treating autonomic nervous system dysfunctions
Methods and systems for alleviating disorders and complications associated with autonomic nervous system dysfunction. The approach generally includes measuring heart rate signals from a subject to measure heart rate variability and determine a heart rate variability threshold, determining that the subject is experiencing autonomic nervous system dysfunction, and alerting the subject to stimulate the auricular branch of the vagus nerve with an ear device.
US11357969B2 Implantable stimulation node configuration
Methods, systems, and devices for implantable node are described. The method may include storing, at an implantable stimulation node, a set of stimulation profiles in a memory during a configuration phase. The method may also include receiving a stimulation command corresponding to a stimulation profile of the set of stimulation profiles during a treatment phase. The method may further include delivering stimulation based at least in part on the stimulation profile corresponding to the received stimulation command. In some cases, the system may include an implantable hub, an implantable sensing node, and a sensing device.
US11357967B2 Impeller for catheter pump
An impeller for a pump is disclosed herein. The impeller can include a hub having a fixed end and a free end. The impeller can also have a plurality of blades supported by the hub. Each blade can have a fixed end coupled to the hub and a free end. The impeller can have a stored configuration and a deployed configuration, the blades in the deployed configuration extending away from the hub, and the blades in the stored configuration being compressed against the hub.
US11357966B2 Compounding device, system, kit, software, and method
An exemplary compounding system and method can include two pump heads for simultaneously drawing two different fluids from at least two separate input containers such that the at least two different fluids are mixed and distributed to an output container. The system can include a manifold that maintains separation of certain of the different fluids until after passing by a first pump and a second pump and/or additional pumps. A junction can be placed in the fluid line downstream of the first and second pumps and/or additional pumps such that all or some of the fluids are mixed prior to output to the output container. The method of using the system can include incorporating software that selects various fluids at certain times and sequences to ensure optimum efficiency and safety for the system, and can continue compounding actions even when an input supply container runs out or otherwise fails to supply a particular fluid/material. The method of use also includes connection of a transfer set to a housing in a manner that further ensures optimum efficiency and safety.
US11357965B2 Antimicrobial caps for medical connectors
The present invention relates to a cap for a medical connector. More specifically, the present invention related to an antimicrobial cap for placement over a connector, wherein various features of the antimicrobial cap maintain the connector in an antiseptic state.
US11357963B2 Aseptic coupling devices
An aseptic coupling arrangement can include a first coupling device and a second aseptic coupling device. In one embodiment, the first and second coupling devices are substantially similar, each having a main body defining a front face and a fluid passageway therethrough. A first connecting feature disposed on the main body of each coupling device may be provided for aligning and coupling the aseptic devices together. Each coupling device may also include a sealing member received in the main body and a membrane removably coupled to the main body front face to cover the sealing member. The first aseptic coupling device may also include a rotatable protective cover that is removably attached to the main body and connected to the membrane. In one embodiment, the removal of the protective covers away from two coupled main bodies, in a direction parallel to the front faces, causes removal of the membranes.
US11357961B2 Connector for connecting a catheter to a fluid transfer system
The invention relates to a connector (1) for connecting a catheter (2) to a fluid transfer system comprising a main body (11) with a tubular pin (111) adapted to be inserted into an end portion (21) of the catheter (2) such as to provide a fluid connection between the catheter (2) and the tubular pin (111). The connector (1) is characterized in that a fixing means (12) is movably connected to the main body (11), wherein the fixing means (11) is adapted to fix the catheter (2) to the connector (1) when the fixing means (12) is in a fixing position.
US11357960B2 Devices for delivering substances through an extra-anatomic opening created in an airway
Devices and methods for delivering substances to lung tissue through an extra-anatomic passage created in an airway.
US11357948B2 Humidifier reservoir
An integrated respiratory pressure therapy device and humidifier for pressurising and humidifying breathable air to treat a respiratory disorder in a patient, includes a blower configured to pressurise the breathable air; a water reservoir configured to hold a volume of water to be used for humidification of the breathable air, the water reservoir comprising a water reservoir base, a water reservoir lid connected to the water reservoir base, and a compliant portion. The compliant portion is constructed from an elastomeric material and configured to seal between the water reservoir base and the water reservoir lid. A water reservoir dock forms a cavity configured to partially receive the water reservoir. The water reservoir lid includes a protrusion and the water reservoir dock includes a recess configured to releasably engage one another to secure the water reservoir to the water reservoir dock.
US11357947B2 Humidifier reservoir
An apparatus for humidifying a flow of pressurised, breathable air includes varying a first pressure of the flow of breathable gas to vary a level of thermal engagement between the conductive portion of the reservoir and the heater plate, varying a height of the variable portion varies a level of thermal engagement between the conductive portion of the reservoir and the heater plate, use of a humidifier reservoir base component with a maximum water capacity substantially equal to the predetermined maximum volume of water of the humidifier reservoir or the use of intersecting inlet and outlet axes.
US11357945B2 Nasal pad for respiratory mask and respiratory mask
A nasal pad for respiratory mask and a respiratory mask. The nasal pad comprises a nasal pad body and nasal plugs. Each nasal plug comprises a nasal plug body. The nasal plug bodies are fixedly connected to the nasal pad body. The nasal pad body comprises extend-retract adjustment sections. The extend-retract adjustment sections are provided with an extended length and a retracted length. The extend-retract adjustment sections are configured in a way that the length thereof can be adjusted between the extended length and the retracted length, thus varying the distance between the two nasal plug bodies. One purpose of the nasal pad is for use in the respiratory mask.
US11357942B1 Insertion guide for endotracheal tube
An insertion guide facilitates insertion of an endotracheal tube (ETT) into the trachea of a patient instead of the esophagus of the patient. The ETT includes an elongated, somewhat flexible, generally hollow tube and the insertion guide includes an elongated, solid and relatively rigid shaft that is configured to be positioned within the hollow tube of the ETT. The shaft is provided with a radiused portion and/or an angled portion adjacent a distal end of the insertion guide that protrudes outwardly beyond a distal end of the ETT. The radiused portion and/or the angled portion of the shaft facilitate insertion of the distal end of the ETT past the epiglottis and into the trachea of the patient instead of into the esophagus of the patient.
US11357941B2 Breathing apparatus, method of controlling a breathing apparatus, computer program and computer program product
A breathing apparatus includes a control unit configured to control operation of the breathing apparatus based on at least a first input value and a second input value. The breathing apparatus also includes a graphical user interface connected to the control unit. The control unit is configured to display a visual output on the graphical user interface including an area defined by a first axis and a second axis. In addition, the breathing apparatus includes an input unit configured to provide selection of a portion of the area. The control unit is configured to set the first input value in response to the position of the selected portion relative the first axis and to set the second input value in response to the position of the selected portion relative the second axis.
US11357939B2 Breathing lung device
A device for placing a lung in a variety of different inflation states using positive air pressure. An exemplary device includes a housing and an air supply component. The housing includes a platform receives at least one of a synthetic lung or a real lung. The platform is at the same air pressure as a surrounding environment. The air supply component is located within the one or more internal cavities of the housing. The air supply component inflates the synthetic lung or the real lung with positive pressure.
US11357937B2 Collapsible fiber matrix reservoir for an e-vaping device
Example embodiments relate to a cartridge configured to house a pre-vapor formulation for an e-vaping device, the cartridge including an inner portion and an outer portion configured to store the pre-vapor formulation. The outer portion includes a plurality of fibers configured to be mobile and/or configured to be substantially free of entanglement with one another. The fibers are configured to be substantially free of entanglement with one another based on the lengths of the plurality of fibers. For example, the lengths of the plurality of fibers may be in a range of about 3 mm to about 7 mm. The lengths may also be about 5 mm.
US11357935B2 Drug delivery device with electronics
A system may include a mobile application residing on an external device and an inhalation device. The inhalation device may include a mouthpiece, a mouthpiece cover, medicament, and an electronics module comprising a processor. The inhalation device may be configured to both prepare a dose of medicament for delivery to a user and cause the processor to transition between power states when the mouthpiece cover is moved from a closed position to an open position to expose the mouthpiece. The electronics module or the mobile application may be configured to generate usage events based on usage of the inhalation device by the user. The electronics module may also include a pressure sensor, and the electronics module or the mobile application may be configured to determine whether a usage event is a good inhalation event, a fair inhalation event, or a no inhalation event based on feedback from the pressure sensor.
US11357931B2 Mesh for use in a nebuliser, and a method of manufacturing the same
There is provided a mesh for use in forming droplets of liquid in a nebuliser, the mesh comprising a first portion (22) made of a first material having a plurality of holes passing therethrough; and a second portion (26) made of a second material that is in contact with the first portion (22), the second portion (26) having a corresponding plurality of holes passing therethrough, the plurality of holes in the second portion forming nozzles (28) for an outlet side of the mesh; wherein the first material has a higher density than the second material.
US11357930B2 Syringe opening confirmation structure
An object of the present invention is to provide a tamper-evident structure of syringe that enables a user to recognize at a glance the fact that the syringe is already unsealed. A cap 4 of the syringe 2 includes a cover 5 that covers a distal end of a nozzle 21, a sealing plug 7 that is elastic and seals the distal end of the nozzle 21 in a state of being attached to the inside of the cover 5, and a tamper ring 6 that includes a restraining part that is separably connected to the syringe 2 and the cover 5 that presses the sealing plug 7 against the distal end of the nozzle 2.
US11357928B1 Medical waste disposal and container washing system
A medical waste disposal and container washing system includes loading and unloading stations, the loading station configured for placing a medical waste container on a conveyor system. An inversion station is located downstream along the conveyor system, operable to reorient the container from a first orientation in which medical waste is retained to a second orientation in which the medical waste is discharged from the medical waste container by gravity as the medical waste container is moved within the inversion station. A first wash station along the conveyor system washes an interior of the container that has been reoriented. A second wash station is located downstream along the conveyor system.
US11357926B2 Drug delivery device with sound transducer
A drug delivery device is provided comprising a drug-filled cartridge or means for receiving a drug-filled cartridge, and drug expelling means comprising expelling means for expelling an amount of drug from the cartridge, and an indicator member arranged to move corresponding to an action performed on or by the drug delivery device. The device further comprises an energy source, wireless communication means, sensor means adapted to detect movement of the indicator member, and a processor adapted to (i) receive input from the drug delivery device indicative of indicator member movement and (ii) control the communication means to transmit a data signal comprising coded information derived from received input from the sensor means, wherein the wireless communication means is in the form of a sound transducer.
US11357925B2 Automatic injection device provided with a device for generating sound signals
An automatic injection device includes an injection syringe for injecting liquid provided with a syringe body carrying an injection needle and a piston rod mounted to be able to move inside this syringe body to cover an injection stroke during which the liquid is injected, an external casing and a positioning control member that are telescopic, the relative movement of which controls the operation of the automatic injection device, and control members arranged to selectively control the movement of the syringe body and the movement of the piston inside the positioning control member in order to automatically inject the liquid present in the injection syringe, the automatic injection device further comprising a device for generating sound signals activated during the automatic injection of the liquid present in the injection syringe so as to generate a series of sound signals from the start to the end of the injection.
US11357914B2 Multi chamber syringe unit
A multi chamber syringe unit includes a body, a separating element and a bypass arrangement. The body has a distal end side, a proximal end side opposite to the distal end side, an interior limited by a side wall between the distal end side and the proximal end side and a longitudinal axis centrally extending from the distal end side to the proximal end side through the body. The separating element is arranged in the interior of the body forming a distal chamber between the distal end side and the separating element and a proximal chamber between the proximal end side and the separating element. The bypass arrangement is a section of the body in which the interior has a constant noncircular cross section orthogonal to the longitudinal axis. The multi camber syringe unit allows for being efficiently prepared and for efficiently providing or administering high quality of prefilled products.
US11357908B2 Tamper evident closure container
A closure container that can house a preset drug applicator in an easily accessible manner with tamper evidencing means. The closure container contains a plurality of dosing ribs and a retainer to retain the syringe in a preset dosage amount and preferably has a window to view the barrel of the syringe.
US11357906B2 Systems and methods for detecting operational conditions of reduced pressure therapy
In some embodiments, a negative pressure wound therapy system can detect and classify one or more operational conditions, including detection of a wound bleeding. The system can react to detection of blood by providing an indication, reducing the intensity or stopping therapy, releasing negative pressure, etc. In certain embodiments, the system can detect one or more additional operational conditions, such as change in vacuum pressure, gas leak rate change, exudate flow rate change, water flow rate change, presence of exudate, presence of water, etc. The system can detect and distinguish between different operational conditions and provide indication or take remedial action.
US11357904B2 System for providing fluid flow to nerve tissues
An apparatus and system for providing reduced pressure to a defect in a nerve is disclosed. The apparatus comprises a nerve conduit having a generally tubular shape that has walls including a luminal wall surrounding the tissue site to contain fluids within a luminal space between the tissue site to contain fluids within a luminal space between the tissue site and the luminal wall. The apparatus further comprises a manifold having a porous body and a connector for receiving reduced pressure, wherein the manifold is positioned within the luminal space adjacent the tissue site to distribute the reduced pressure to the defect. Additionally, a method for providing reduced pressure to a defect in a nerve is disclosed that includes implanting the nerve conduit and manifold at a site of damaged nerve tissue and applying a reduced pressure to the manifold thereby stimulating repair or regrowth of nerve tissue.
US11357903B2 Wound packing
A wound packing material is provided, suitable for use in negative pressure wound therapy, including a body of a porous material, the body including frangible regions defining a plurality of portions, the frangible regions allowing the portions to be selectively removed from the body. Methods of manufacturing the wound packing material, and methods of its use are also provided.
US11357900B2 Systems and methods for priming a fluid circuit
Methods and systems for priming a disposable fluid circuit for the processing of a biological fluid are disclosed. The methods and systems allow for variable and configurable priming of the flow path(s) leading to one or more biological fluid source containers.
US11357896B2 Dialysis system with artificial intelligence
Constraining adaptive optimizations of a state of an operation module of a medical device includes determining if a new state has at least one operational parameter that is outside a constraint that has been provided to the medical device in a non-repudiable manner, accepting the new state if no operational parameters are outside any of the constraints, and reverting the medical device to a previous valid state if at least one operational parameter is outside at least one of the constraints. The adaptive optimizations may be provided using artificial intelligence along with relevant inputs thereto. The medical device may be a dialysis system. Constraint data may be provided to the medical device along with a one-way hash value of the constraint data using, for example, a SHA 256 hash. The one-way hash value may be digitally signed using a private key that is part of a public/private key pair.
US11357895B2 Method and apparatus for degassing liquids
The present invention relates to an apparatus for degassing liquids comprising a degassing system, wherein the degassing system has a first degassing chamber, a second degassing chamber, a liquid store, a pump, and a supply line that connects the liquid store to the first degassing chamber; wherein the pump is connected to the first degassing chamber at the intake side and to the second degassing chamber at the pressure side; and wherein the degassing system furthermore has a return line that can be cut off and that connects the two degassing chambers to one another, and wherein the apparatus comprises a controller that is configured to operate the degassing system in a first operating mode and in a second operation mode; wherein the degassing system is connected in the first operation mode such that the pump conducts liquid away from the first degassing chamber and supplies it to a removal unit for degassed liquid; and wherein the degassing system is connected in the second operating mode such that liquid is returned from the second degassing chamber to the first degassing chamber through the return line.
US11357893B2 Breast pump system
The invention is a wearable breast pump system including a housing shaped at least in part to fit inside a bra and a piezo air-pump. The piezo air-pump is fitted in the housing and forms part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm is removably mounted on a breast shield.
US11357890B2 Customized hybrid bone-implant grafts
The present invention provides customized hybrid bone-implant grafts and a method of manufacture thereof.
US11357885B2 Internal compression treatment (ICT)
A system related to the reparation of damaged veins along with the suspension of venous stasis progression by minimizing the leak reflux flow and the protection of the valve functions of the vena saphena magna, parva, perforator veins by means of exovascular or external filling agent injection in the treatment of venous stasis (which is also called varicose vein or varicose treatment).
US11357884B2 Electroactive bioadhesive compositions
The present invention relates to electrochemically initiated bioadhesive compositions comprising biocompatible polymers containing derivatives of diazonium, arylsulfonium, or diaryliodonium in general, and to their use in tissue fixation, in particular.
US11357882B2 Method, apparatus and system for reducing pathogens in a breathable airstream in an environment
An air flow system for reducing pathogens in a breathable airstream in an environment has a device having an airstream intake for receiving a volume of untreated air located in a first position, an airstream outlet for expelling a volume of treated air, the airstream outlet located in a second position extending above the first position, a flow path extending between the airstream intake and the airstream outlet, at least one of a UV generator and a UV-C emitter optically coupled to the flow path, a power source operably connected to the one of the at least one of the UV generator and the UV emitter, and a pressure generator fluidly connected to the airstream intake, the pressure generator configured to impart a flow from the airstream intake to the airstream outlet, wherein the pressure generator can be at least one of a force of flow from in line pressurized source or provided by a fan within the housing, and wherein a portion of the flow path includes a UV-C highly reflective surface.
US11357879B2 Far UV C power supply
An excimer bulb assembly, with an excimer bulb, at least one integral captured reflector, and an integral filter such that the excimer bulb only emits substantial UV radiation between 200 nm and 230 nm, using a filter that passes light from about 200 nm to 234 nm (+/−2 nm).
US11357872B2 Imaging neurotransmitters in vivo using functionalized carbon nanotubes
Imaging based detection of changes in extracellular neurotransmitter concentration in living tissue is achieved using novel nanotube-based sensors. The sensors are functionalized, neurocompatible single-walled carbon nanotubes (SWNT) comprising an adsorbed neurotransmitter analyte selective polynucleotide.
US11357871B2 Challenge test for diagnosing subtypes of ASD
The present invention is directed to a method for differentiating between ASD phenotype 1, phenotype 2 and other ASD patients, wherein the method comprises: administering an Nrf2-activator to a subject, and identifying the subject as an ASD phenotype 1 patient if the subject shows a negative response, as a phenotype 2 patient if he shows a positive response and as another ASD patient if he does not show a positive nor a negative response, wherein the subject is a patient previously diagnosed with idiopathic ASD or a subject displaying clinical signs of ASD. Likewise, the present invention is directed to an Nrf2-activator for use in differentiating between autism spectrum disorder (ASD) phenotype 1 patients, phenotype 2 patients and other ASD patients, wherein the Nrf2-activator is administered to a subject, wherein a phenotype 1 patient is identified by a negative response, a phenotype 2 patient is identified by a positive response and other ASD patients are identified by the absence of a positive and a negative wherein the subject is a patient previously diagnosed with idiopathic ASD or a subject displaying clinical signs of ASD.
US11357869B2 Compositions and methods for treating leber's hereditary optic neuropathy with NADH dehydrogenase proteins
Disclosed herein is a recombinant nucleic acid, comprising: a mitochondrial targeting sequence; a mitochondrial protein coding sequence, wherein said mitochondrial protein coding sequence encodes a polypeptide comprising a mitochondrial protein; and a 3′UTR nucleic acid sequence. Also disclosed is a pharmaceutical composition comprising the recombinant nucleic acid and a method of treating Leber's hereditary optic neuropathy (LHON) using the pharmaceutical composition.
US11357866B2 Expression of HIV inhibitors by mesenchymal stem cells
A composition of matter and method of treating HIV with mesenchymal stem cells (MSC) is disclosed. Specifically, MSCs are transduced with vectors incorporating an anti-viral fusion inhibitor, such as a C46-derived peptide or neutralizing antibody. The transduced MSCs are capable of expression the inhibitor and preventing HIV virus-cell fusion.
US11357864B2 Antibody drug conjugates for ablating hematopoietic stem cells
The present invention provides antibody drug conjugates, wherein an antibody or antibody fragment that specifically binds to human cKIT is linked to a drug moiety, optionally through a linker. The present invention further provides pharmaceutical compositions comprising the antibody drug conjugates; and methods of making and using such pharmaceutical compositions for ablating hematopoietic stem cells in a patient in need thereof.
US11357861B2 Protein complex comprising non-peptidyl polymer-coupled fatty acid derivative compound as linker and preparation method therefor
Provided are a protein conjugate in which a physiologically active polypeptide is linked to a biocompatible material via a non-peptidyl polymer-coupled fatty acid derivative compound serving as a linker, exhibiting an increased duration of physiological activity compared to natural forms and a preparation method therefor. Since an increase in serum half-life of the physiologically active polypeptide of the protein conjugate, in which the biocompatible material, the non-peptidyl polymer-coupled fatty acid derivative compound, and the physiologically active polypeptide are linked, is proved, the protein conjugate may be widely used in the field of protein drugs.
US11357860B2 Targeted delivery of drugs, therapeutic nucleic acids and functional nucleic acids to mammalian cells via intact killed bacterial cells
A composition comprising intact killed bacterial cells that contain a therapeutic nucleic acid, a drug or a functional nucleic acid is useful for targeted delivery to mammalian cells. The targeted delivery optionally employs bispecific ligands, comprising a first arm that carries specificity for a killed bacterial cell surface structure and a second arm that carries specificity for a mammalian cell surface receptor, to target killed bacterial cells to specific mammalian cells and to cause endocytosis of the killed bacterial cells by the mammalian cells. Alternatively, the delivery method exploits the natural ability of phagocytic mammalian cells to engulf killed bacterial cells without the use of bispecific ligands.
US11357858B2 Pharmaceutical compositions for the treatment of postoperative pain
Disclosed are pharmaceutical compositions in gel form comprising a hydrophilic matrix consisting of a hyaluronic acid derivative containing an amide local anaesthetic in base form.
US11357856B2 Lipids for delivery of active agents
Compounds are provided having the following structure: Formula (I) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R, R1, R2, G1, G2 and n are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.
US11357850B2 Methods for treating breast cancer using INOS-inhibitory compositions
Disclosed are methods for treating one or more mammalian cancers, particularly, human breast cancers, including triple-negative breast cancer (TNBC), that employ therapeutically-effective amounts of one or more iNOS pathway-inhibitory compounds, such as L-NMMA, in combination with one or more selected calcium channel antagonists, one or more chemotherapeutic agents, one or more anti-PD-1 antibodies, and one or more doses of ionizing radiation. Also disclosed are pharmaceutical formulations that comprise these compositions, as well as methods for their use in treating refractory, metastatic, and/or relapsed cancers, or, for use in the management or reversal of treatment resistance in one or more types of human breast cancer.
US11357849B2 Anti-nucleolin antibodies
The present disclosure provides anti-nucleolin antibodies, methods of producing anti-nucleolin antibodies, and cells producing anti-nucleolin antibodies. Also provided are methods of using anti-nucleolin antibodies in treating malignant and non-malignant diseases.
US11357846B2 Method of producing pharmaceutical compositions comprising immunogenic chikungunya virus CHIKV-Delta5NP3
The present invention relates to a process for producing an immunogenic live attenuated Chikungunya virus, as well as pharmaceutical compositions comprising the same.
US11357843B2 Bacteriologically-modified whole-cell tumor vaccine and method of making same
Disclosed are a bacteriologically-modified whole-cell tumor vaccine and a method of making the same. The method includes: lysing bacteria at logarithmic growth phase to obtain a bacterial lysate; mixing the bacterial lysate with an excessive amino compound solution to aminate the bacterial lysate in the presence of EDC; mixing the aminated bacterial lysate with the tumor cells for a certain period of time to produce bacteriologically-modified tumor cells; and inactivating the bacteriologically-modified tumor cells to produce the bacteriologically-modified whole-cell tumor vaccine. The bacteriologically-modified whole-cell tumor vaccine has been demonstrated to have desirable therapeutic effect in tumor model mice.
US11357842B2 PD-L1 targeting DNA vaccine for cancer immunotherapy
The present invention relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding PD-L1. In particular, the present invention relates to said attenuated strain of Salmonella for use in the treatment of cancer.
US11357840B2 Methods and compositions for reducing growth, migration and invasiveness of brain cancer stem cells and improving survival of patients with brain tumors
The described invention relates to a pharmaceutical composition comprising a therapeutically effect amount of a therapeutic agent, wherein the therapeutic agent is effective (1) to reduce tumor growth, migration, invasion or a combination and (2) improve subject survival relative to a control. The described invention also relates to a method of treating a subject with a tumor, the method comprising: (1) providing a pharmaceutical composition; and (2) administering the pharmaceutical composition, wherein the composition comprises a therapeutically effective amount of a therapeutic agent which is effective to reduce tumor growth, migration, invasion or a combination. The method may further comprise preparing therapeutic agent and preparing the pharmaceutical composition. The therapeutic agents include but are not limited to Wnt5a derivative peptides or Wnt5a antagonists or Wnt5a blocking antibody. The tumor comprises a population of cancer stem cells.
US11357839B2 Brachyury protein, non-poxvirus non-yeast vectors encoding Brachyury protein, and their use
Brachyury protein can be used to induce Brachyury-specific CD4+ T cells in vivo and ex vivo. It is also disclosed that Brachyury protein can be used to stimulate the production of both Brachyury-specific CD4+ T cells and Brachyury-specific CD8+ T cells in a subject, such as a subject with cancer. In some embodiments, the methods include the administration of a Brachyury protein. In additional embodiments, the methods include the administration of a nucleic acid encoding the Brachyury protein, such as in a non-pox non-yeast vector. In further embodiments, the method include the administration of host cells expressing the Brachyury protein.
US11357837B2 Implantable matrix having optimum ligand concentrations
Implantable matrices and methods are provided. The matrices are configured to fit at or near a target tissue site, the matrices comprise biodegradable materials and ligands bound to the matrices and are configured to bind receptors and allow influx of cells into the implantable matrices, wherein the ratio of ligands to receptors is from about 1.5 to about 0.5.
US11357835B2 Compositions and methods for the treatment or the prevention of E. coli infections and for the eradication or reduction of E. coli surfaces
Compositions and methods for treating or preventing E. coli infections are provided. The compositions can be formulated as pharmaceutical compositions or as disinfectants, sanitizers, detergents or antiseptics, and can be used to eradicate or reduce E. coli populations and thereby treat or prevent infection by E. coli. The compositions include one or more digestive enzymes, e.g., one or more protease, lipases, and amylases. Methods of use of the compositions are also provided.
US11357834B2 Recombinant α-galactosidase A for treatment of Fabry disease
Described are compositions comprising α-galactosidase A enzymes with unique carbohydrate profiles, as well as methods for manufacturing and purifying such enzymes. Also described methods of treating, preventing, and/or ameliorating Fabry Disease by administering such enzymes to a subject in need thereof. Also described are compositions comprising migalastat in combination with such α-galactosidase A enzymes.
US11357831B2 Sequence-specific antimicrobials by blocking DNA repair
The invention relates to the improvement of endonuclease-based antimicrobials by blocking DNA repair of double-strand break(s) (DSB(s)) in prokaryotic cells. In this respect, the invention especially concerns a method involving blocking DNA repair after a nucleic acid has been submitted to DSB, in particular by a Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) associated programmable double-strand endonuclease. The invention particularly relates to the use of an exogenous molecule that inhibits DNA repair, preferably a protein that binds to the ends of the double-stranded break to block DSB repair. The invention also relates to vectors, particularly phagemids and plasmids, comprising nucleic acids encoding nucleases and Gam proteins, and a pharmaceutical composition and a product containing these vectors and their application.
US11357829B2 Systems, compositions and methods for treating diabetes
This disclosure provides methods for treatment comprising co-administering insulin and glucagon to a subject, and co-formulations comprising insulin and glucagon.
US11357826B2 IL-10 EGFR antibody fusion protein and uses thereof
The present disclosure provides proteinaceous complexes, pharmaceutical compositions, medicaments and/or kits comprising the proteinaceous complexes, methods for producing the proteinaceous complexes, and uses thereof.
US11357819B2 Cytocidal agent
The present invention is a cytocidal agent including a peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 and a site selectively binding to a target molecule, in which the peptide consisting of an amino acid sequence represented by SEQ ID NO: 1 is a peptide exclusively consisting of L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to the 14th amino acids are D-amino acids, and the 15th to 19th amino acids are L-amino acids, a peptide in which, in amino acid sequences represented by SEQ ID NO: 1, the first to 14th amino acids are L-amino acids, and the 15th to the 19th amino acids are D-amino acids, or a peptide exclusively consisting of D-amino acids.
US11357817B2 Immunoproteasome inhibitor
Methods and pharmaceutical compositions for treating malaria and immune related disorders are provided. The pharmaceutical compositions include an effective amount a carmaphycin B analog that inhibits immunoproteasome activity in a subject.
US11357815B2 Method for processing raw sugarcane maximizing the preservation of policosanols during production of a natural sugarcane juice-based product
A method for processing sugarcane juice from raw sugarcane stalks to produce various forms of a natural sugarcane juice product preserves policosanols naturally occurring in the raw sugarcane stalks, resulting in policosanol-rich natural sugarcane juice-based products such as a drinking beverage, a concentrated sweetening agent, and a nutraceutical product. The method may include steps of providing sugarcane stalks having high policosanol concentrations; extracting sugarcane juice from the sugarcane stalks via a series of roller mills; filtering the extracted sugarcane juice; stabilizing the pH of the juice in a non-acidic solution of calcium hydroxide; flocculating the sugarcane juice to remove undesirable impurities; optionally, evaporating the sugarcane juice to form a policosanol-rich sugarcane juice concentrate and extracting the sugarcane juice concentrate from the evaporator.
US11357809B2 Herbal preparation for stimulation of hair growth, control of hair fall, dandruff and infections thereof using Ageratum spp
This disclosure describes herbal preparations for the stimulation of hair growth, control of hair fall, control of dandruff, and control of dandruff-related infections thereof, using herbaceous plants, Ageratum spp. Processes for preparing the herbal preparations and methods for using them are also disclosed. Such an herbal preparation using plants, Ageratum spp. can be utilized as an efficient hair care solution in a wide range of hair growth related problems of humans in a cost-effective manner.
US11357808B1 Method of preparing cannabis extracts
The invention relates to a method of preparing cannabis extracts, including shatter, budder and wax extracts. The extraction method can provide a high quality and pure extraction product of THC from cannabis plant material, as either a shatter, wax or budder end extraction product. The extracted product is free of polar cannabis plant material, chlorophyll and residual solvents, has a high concentrate of THC, and can be used for dabbing, vaping or smoking consumption by a user. Suitable solvents for the method are gases selected from the group consisting of propane, butane or iso-butane, and the preferred solvent is propane. A key step of the method of the present invention is recovering solvent under atmospheric vacuum and, therefore, obtaining an extraction product that is purified of solvent and has no solvent.
US11357804B2 Application of oncolytic viruses as immunostimulants for treatment of tumors and/or cancers
Provided is the use of selectively replicating oncolytic viruses in the preparation of immunostimulants for treatment of tumors and/or cancers, wherein the oncolytic viruses do not carry exogenous immunoregulatory genes.
US11357800B2 Compositions for the treatment of neuropathic pain and sensitization of tumors to chemotherapies
Without limitation, a method for preventing and/or treating neuropathic pain in a subject/patient comprising administering a therapeutically effective amount of exosomes derived and isolated from mammalian cells to the subject/patient and a method of treating cancer in a subject/patient in need thereof, comprises administering a combination comprising a therapeutically effective amount of exosomes derived and isolated from mammalian cells and a chemotherapeutic agent.
US11357797B2 Peptides and combination of peptides of non-canonical origin for use in immunotherapy against different types of cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11357793B2 Pharmaceutical formulations for the treatment and prevention of trauma-induced neuropathology and neurodegeneration
Novel multi-component formulations, procedures and methods for use in treating neuropathology and neurodegeneration incident to trauma are provided. Multi-component formulations of the invention comprise biologically active forms of any two, any three, or all four of at least one neurosteroid or neuroactive steroid, such as progesterone or synthetic progestin, at least one anti-epileptic or anticonvulsant, such as gabapentin, pregabalin or valproic acid, at least one NK-1 receptor antagonist, such as aprepitant, casopitant or vestipitant, at least one lithium-containing or lithium-related drug. The provided formulations are configured or adapted to prevent or reduce the incidence and severity of neurological damage caused by trauma, or the risk of such damage. Formulations, procedures and methods of the invention advantageously effect both neuroprotective actions to prevent or reduce secondary injuries, and neurotrophic actions to repair and restore cells and tissues affected by the trauma, and are especially useful in treating injury or trauma to nerve cells, to neural support cells and to neural support tissues.
US11357788B2 Nuclear paraspeckle assembly transcript 1 as therapeutic targeting in neurodegeneration
The present disclosure provides a method of reducing neurodegeneration and/or TDP43 associated aggregation, comprising knocking down the expression of Nuclear Paraspeckle Assembly Transcript 1 (NEAT1) or LncRNA NEAT1. Also provided are methods for screening a candidate agent that reduces neurodegeneration and/or TDP43 associated aggregation in a cell, treating or preventing a neurodegenerative disorder, delaying or preventing the onset of a neurodegenerative disorder or reducing a risk for developing a neurodegenerative disorder in a subject and determining whether a subject is suffering from, or at a risk of developing a neurodegenerative disorder, comprising measuring the presence of cytoplasmic NEAT1 in a biological sample, wherein the presence is indicative of the risk of developing a neurodegenerative disorder.
US11357783B2 Conjugate of finasteride with peptide
A composition for preventing hair loss and, more specifically, to a compound having a structure in which finasteride and a peptide are linked through a covalent bond and a pharmaceutical composition or a cosmetic composition for preventing hair loss or promoting hair growth comprising the same. The compound having a structure in which finasteride and a peptide are linked through a covalent bond is excellent in physiological activities such as hair loss improvement, hair growth promotion, cell growth promotion, etc., is excellent in stability in water and skin permeation, and thus can be effectively used as a composition for preventing hair loss and promoting hair growth.
US11357781B2 Non-catalytic substrate-selective, p38α-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity, and methods of use thereof
Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.
US11357780B2 Methods and compositions relating to the inhibition of IP6K1
The technology described herein is directed to methods of treating lung infections and/or lung inflammation (e.g, pneumonia) by inhibiting IP6K1.
US11357779B2 G1T38 superior dosage regimes
A G1T38 human oral dosage regime that provides a (mean AUC(0-24),ss (h*ng/mL))/(dose (mg)) ratio of less than 5 and/or a (mean AUC(0-24),ss (h*ng/mL))/(Absolute Neutrophil Count (cells/mm3)) ratio on day 22 of dosing of not greater than 1.25.
US11357770B2 Method of treating immunoglobulin light chain amyloidosis
The present invention relates to the use of substituted quinoline compounds for treating immunoglobulin light chain (LC) amyloidosis (AL), especially cardiotoxicity associated with immunoglobulin LC AL. In particular, the substituted quinoline compounds useful in the treatment of cardiac LC amyloidosis are 5,7-dihalo-8-hydroxyquinoline derivatives, especially 5,7-dichloro-8-hydroxyquinoline derivatives.
US11357769B2 Drug combinations for reducing cell viability and/or cell proliferation
Provided herein is a combination of agents for reducing cell viability and/or cell proliferation. The combination comprises an FGFR4 inhibitor and an EGFR inhibitor.
US11357768B2 Methods for treating NASH and for preventing NASH-induced HCC
Disclosed are methods of treating non-alcoholic steatohepatitis (NASH) and methods of preventing NASH-induced hepatocellular carcinoma (HCC), such methods including administering O-(3-piperidino-2-hydroxy-1-propyl)-nicotinic amidoxime (BGP15), alone or in combination with a inhibitor of the interleukin-6 receptor transsignaling response, particularly gp130Fc.
US11357767B2 Compounds for use in treating depression and migraine
The invention relates to amide-derivatives of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid for use in a treatment for preventing or suppressing symptoms associated with mood disorders, headaches and migraine. The compounds of the invention can be used to treat any subject suffering from a mood disorder, headaches and/or migraine but can specifically be used to treat a mood disorder, headaches and/or migraine in patients suffering from a mitochondrial disease.
US11357764B1 Methods of treating Fabry patients having renal impairment
Provided are methods for treatment of Fabry disease in patients having HEK assay amenable mutations in α-galactosidase A. Certain methods comprise administering migalastat or a salt thereof every other day, such as administering about 150 mg of migalastat hydrochloride every other day.
US11357762B2 Methods of treating Fabry patients having renal impairment
Provided are methods for treatment of Fabry disease in patients having HEK assay amenable mutations in α-galactosidase A. Certain methods comprise administering migalastat or a salt thereof every other day, such as administering about 150 mg of migalastat hydrochloride every other day.
US11357759B2 Composition including ADAM9 inhibitor and the use thereof
The present disclosure relates to an ADAM9 inhibitor compound of formula (I), including salts, hydrates and stereoisomers thereof, compositions thereof, and methods of use therefor, including treating a person in need thereof with an effective amount of the compound or composition, and detecting a resultant improvement in the person's health or condition.
US11357756B2 Anesthetic compositions and methods comprising imidazoline compounds
Effective implantable medical devices and methods for reducing and treating acute pain by providing local anesthesia and nerve blockade using an imidazoline compound, such as clonidine are provided. In some embodiments, there is an injectable pharmaceutical composition comprising a therapeutically effective amount of imidazoline compound in a liquid pharmaceutical carrier, where the imidazoline compound provides local anesthesia and nerve block to the target tissue site which is a dorsal root ganglion, peripheral nerve fiber and/or peripheral nerve root.
US11357755B2 Compounds for controlling arthropods
The present invention relates to novel halogen-substituted compounds, to processes for their preparation and to their use for controlling animal pests, in particular arthropods and especially insects and arachnids.
US11357752B2 Carolacton and derivatives thereof for use in the treatment of cell proliferation disorders
Chemical compounds are provided that are useful in the treatment of diseases associated with an activity of a 5,10-methylenyltetrahydrofolate cyclohydrolase/5,10-methylene tetrahydrofolate dehydrogenase enzyme in pathological eukaryotic cells. In particular, compounds that exhibit inhibitory activity upon 5,10-methylenyltetrahydrofolate cyclohydrolase/5,10-methylene tetrahydrofolate dehydrogenase enzymes and their use in the treatment of cancer and/or parasitic diseases are provided.
US11357749B2 Methods for treating neutropenia
The disclosure provides methods for treating, controlling or mitigating leukopenia (e.g. neutropenia) and/or thrombocytopenia, for example in the context of cancer chemotherapy, comprising administration of a monoacetyl-diacyl-glycerol compound, as well as compositions useful therefor.
US11357748B2 Methods for treating mendelian disorders of the epigenetic machinery
A method is provided for treating a Mendelian disorder of the epigenetic machinery in a subject in need thereof. In particular, the method comprises administering a therapeutically effective amount of an agent that restores balance between open and closed chromatin states at one or more target genes, wherein the agent that restores balance between open and closed chromatin states at one or more target genes is an agent that ameliorates the effect of a defective gene encoding a component of the epigenetic machinery.
US11357747B2 Amino acid compositions for the amelioration of symptoms of hangover
The subject invention provides therapeutic compositions, and uses thereof for the treatment or amelioration of symptoms of a disease selected from the group consisting of: Ebola virus infection, HIV infection, ataxia, environmental enteropathy, cancer, hangover, inflammatory disease, and porcine epidemic diarrhea. In preferred embodiments, the composition includes a combination of one or more amino acids selected from the group comprising lysine, aspartic acid, glycine, isoleucine, threonine, tyrosine, valine, tryptophan, asparagine and/or serine.
US11357742B2 Methods for treating cancer
The present invention relates to methods of treating patients with advanced forms of cancer, such as clear cell renal cell carcinoma, in which X4P-001 is administered in order to reduce angiogenic escape that typically occurs with TKI therapy. The methods demonstrate surprising results, including regression of tumor size and cell number, with comparatively little toxicity.
US11357735B2 Particles and compositions comprising the same for transfection
The present invention relates to the localized delivery of nucleic acids to cells using polyelectrolyte assemblies in the form of particles that are prepared by layer-by-layer deposition of nucleic acid and specific polycation. It also relates to compositions comprising said particles and methods for the treatment of disorders or diseases by administration of such particles.
US11357730B2 Controlled activation ingestible identifier
Apparatuses for use with a pharmaceutically acceptable carrier. The apparatus can include a partial power source, which in turn includes electrodes or materials that are configured to generate an electrical potential upon contacting or being exposed to an ionic solution. The apparatus can further include a circuit electrically or communicatively coupled to the partial power source. The circuit can generate various types of signals, such as RF signals, when powered by the partial power source. The circuit is stably fittable to the pharmaceutically acceptable carrier. The apparatus can further include a barrier, a protective layer, or a membrane that isolates the electrodes or materials from the ionic solution and is configured to be dissolved by the ionic solution.
US11357728B2 Liposome having inner water phase containing sulfobutyl ether cyclodextrin salt
A liposome comprising bilayer and inner water phase is disclosed. Said inner water phase may contain sulfobutyl ether cyclodextrin and an active compound.
US11357727B1 Manufacturing of bupivacaine multivesicular liposomes
Embodiments of the present application relate to commercial manufacturing processes for making bupivacaine multivesicular liposomes (MVLs) using independently operating dual tangential flow filtration modules.
US11357725B2 Delivery of agents using metastable liposomes
Metastable liposomal formulations for hydrophobic drug delivery to a tissue or tissue lumen such the bladder have been developed. These are at least one micron in diameter and formed of one or more lipids having entrapped in the lipid a hydrophobic therapeutic, prophylactic or diagnostic agent. The greater stability of these liposomes, as well as the enhanced transfer of entrapped agent into the adjacent tissue, provides for better delivery, especially of hydrophobic agents such as tacrolimus which does not penetrate tissue well. The metastable liposomal formulations can be administered locally, preferably by instillation, or topically, for example, by spraying or painting, to a tissue or tissue lumen such as the bladder in need of treatment.
US11357719B2 Method for obtaining a diglycoside-enriched Armeria maritima extract, and use thereof in cosmetics
Disclosed are a method for preparing a hydroalcoholic extract obtained from a biomass of the shoots of a plant from the family of Plumbaginaceae, a butanol extract of Armenia maritima, a method for the preparation thereof, the use thereof, and compositions containing same.
US11357717B2 Production, composition and application of preparations in a two-chamber application device for neutralizing and inactivating oxidizing, caustic and irritating chemicals on the skin
A device and protective composition is described that is used in the context of first aid for skin contact with acids, bases, oxidizing agents, formaldehyde and fluorides serving to neutralize and inactivate the chemicals. The device comprises a two-chamber applicator that contains a first preparation in a first chamber, such as an antioxidant, and a second preparation in a second chamber, such as a solution that contains a buffer and a calcium salt. The two preparations are mixed just before application and are applied to the affected areas by the device.
US11357711B2 Foaming cleansing composition for topical application
A cleansing composition for cleansing the skin, comprising by weight of the composition, — 20 to 65 wt. % of one or more polyols; and —5 to 25 wt. % of thickeners, comprising a combination of: a) inorganic thickener selected from silica, chalk, talc, clay and combinations thereof; b) cellulosic thickener selected from cellulose, cellulose ether, cellulose ester and combinations thereof; wherein the weight ratio of the inorganic thickener to the cellulosic thickener is in the range of 4:1 to 40:1; —4 to 12 wt. % of non-soap anionic surfactant; —0 to 8 wt. % of amphoteric surfactant; and wherein the weight ratio of the one or more polyols to the thickeners is in the range of 1:1 to 13:1 and wherein the viscosity of the composition is in the range of 200 to 400 Pa-s, measured at 25° C. after 1 minute at 5 rpm.
US11357710B2 Solid mask and preparation method therefor
The present invention provides a solid mask and a preparation method thereof. The solid mask includes a hydrophobic substrate layer and a nanofiber layer, the nanofiber layer has a three-dimensional structure and is electro-spun onto the hydrophobic substrate layer through uniaxial electrostatic spinning technology, and the nanofiber layer is prepared by the following food-grade raw materials in parts by mass: 10 to 30 parts of gelatin, 1 to 30 parts of soya bean lecithin and 0.1 to 10 parts of a functional substance. The present invention provides a solid mask, using gelatin and soya bean lecithin as the framework. The nanofiber layer is a three-dimensional laminate made of fibers having a diameter of a few hundred nanometers. The nanofiber layer has a membrane structure similar to the extracellular matrix. The raw materials of the solid mask are all food-grade raw materials or natural extracts.
US11357709B2 Dental materials based on redox systems with low-odour cumene hydroperoxide derivatives
Radically polymerizable dental material, which contains a combination of a thiourea derivative and a hydroperoxide according to the following Formula (I) as initiator system for the radical polymerization:
US11357708B2 Dental composites with improved storage stability
Dental material which contains (a) at least one mono- or multifunctional radically polymerizable monomer, (b) at least one organic halogen compound as initiator for the radical polymerization, (c) at least one transition metal compound as catalyst and (d) at least one reducing agent. The material is characterized by a high storage stability at room temperature and does not have the disadvantages associated with peroxides.
US11357706B2 Baby bottle holding devices, systems and methods
A support system for a baby bottle includes a support body. The support body includes a first rim at a first end defining a first opening, a second rim at a second end defining a second opening, a channel extending between the first opening and the second opening, a slot extending between the first end and the second end, a neck portion configured to be positioned about a bottle neck of a baby bottle, and a generally convex or generally concave portion extending between the neck portion and the second end. The support system also includes a pair of handle portions coupled to the support body. Each handle portion includes a handle grip portion and a handle attachment portion.
US11357705B2 Portable, reusable dispensing assembly having multiple operating modes
A portable, reusable dispensing assembly having multiple operating modes is provided. The assembly includes a housing having a compartment which is refillable with an elongated medication strip having a plurality of dosage form packages spaced apart along a longitudinal axis of the strip. A bi-directional, electromechanical actuator advances a first end of the strip from the compartment to a dose-ready area in the housing in a dispensing mode of the assembly and loads the strip into the compartment in a loading mode of the assembly. An actuator controller is configured to receive power and direction command signals to controllably supply DC power of a desired polarity to the actuator to control the operating mode of the assembly.
US11357702B2 Liquid transfer system
Disclosed is a transfer device for use in reconstituting dry drugs and for diluting liquid drugs in drug containers. The transfer device includes a multi-port manifold and a connector suitable to be attached to a drug container, a first conduit to transfer a liquid entering an inlet port of the manifold through the connector and into the drug container, and a second conduit to transfer a gaseous fluid through the connector to an outlet port of the manifold. Also disclosed is a closed liquid transfer system which includes the transfer device, a tube connectable to the inlet port for transporting a liquid to the transfer device, a tube connectable to the outlet port for transporting the gaseous fluid away from the transfer device, and a gas collection container to collect the gaseous fluid in the gas transporting tube.
US11357699B2 System and method for distinguishing manual from automated CPR
An exemplary method of identifying a source of chest compressions administered during cardiopulmonary resuscitation (CPR) includes receiving, at a processor, signals indicative of pressure exerted during the chest compressions from at least one sensor communicatively coupled to the processor and disposed at a location on the victim's chest away from an indicated compression point for manual chest compressions, generating a compression waveform based on the received signals, detecting compression waveform features representative of the chest compressions based on the compression waveform, comparing the detected compression waveform features to a pre-determined criterion to discriminate between chest compressions from an automated compression device and manual chest compressions, determining whether the chest compressions are from the automated compression device or the manual chest compressions based on the comparison, and generating an output based on whether the chest compressions are determined to be from the automated compression device or the manual chest compressions.
US11357698B2 System, method and apparatus for pain control and healing
A device for treating a user includes a housing having apertures. The housing has application areas including a convex top surface, a concave bottom surface, a convex rear surface, convex side surfaces and rounded protrusions extending away from the housing. A vibrational source is located in the housing to produce vibration at the application areas. A switch is in operative communication with the vibrational source to control operation of the vibrational source.
US11357695B1 Foot massaging device with first and second handle assemblies
A massaging device includes a first arm having a first arm-first end and a first arm-second end and a second arm connected to the first arm and having a second arm-first end and a second arm-second end. The device also includes a first massaging assembly secured to the first arm-first end and a second massaging assembly secured to the second arm-first end. The device also includes a first handle assembly secured to the first arm-second end and a second handle assembly secured to the second arm-second end. Application of a first force on the first handle assembly and the second handle assembly increases a distance between the first massaging assembly and the second massaging assembly. Application of a second force on the first handle assembly and the second handle assembly decreases the distance between the first massaging assembly and the second massaging assembly.
US11357691B2 Finger motion rail, support therefor and therapy device comprising same and operating method
A finger motion rail is provided for a therapy device for carrying out passive and/or actively-assisted motion of the fingers and thumb of the hand. The therapy device has an upper shell, to which a kinematic motion mechanism of the finger motion rail for each selected finger is connected, each mechanism has a motion drive that is in control engagement with a control system. The kinematic motion mechanism of the finger motion rail, which mechanism has a carriage that moves in a rail provided around the metacarpophalangeal joint and a pivoting lever, is located at the side of each finger for the passive and/or actively-assisted motion of the selected fingers. This allows an individual finger motion rail with the kinematic motion mechanism to be provided for each selected finger, the rail being located at the side of each finger, thus permitting each selected finger to bend and/or stretch without constraint.
US11357690B2 Apparatuses for arm exercise
The invention comprises an apparatus for arm exercise for therapy of a subject. The apparatus comprises a base comprising a planar upper surface. A first set of parallel rails are affixed to said upper surface of the base, the first set of parallel rails comprising a first rail and a second rail positioned parallel to each other and separated from each other by a predefined first distance. A second set of rails comprising at least a third rail having a first end and a second end are also provided, wherein said first end is slidably mounted on the first rail and said second end is slidably mounted on said second end. A sliding mount is slidably affixed to the second set of rails, and configured such that said sliding mount can be slidingly moved between the first end and the second end of the third rail.
US11357689B2 Motion assistance apparatus
A motion assistance apparatus includes a force transmitting frame having a sliding space therein, the force transmitting frame configured to support a distal part of a user, a slider configured to slide in the sliding space, and a driving frame connected to the slider and configured to slide with respect to a proximal part of the user.
US11357678B1 Wheel brush for a wheelchair
A wheel brush for a wheelchair has a brush housing that has a longitudinal channel and an open bottom. A brush head is slidably received within the channel such that bristles located on the brush head extend out through the open bottom of the brush housing. The brush housing is attached to a back of a wheelchair via a connecting arm so as to position the bristles in engaging relationship with a portion of one of the rear wheels of the wheelchair. The connecting arm is either attached directly to the wheelchair or is attached to the wheelchair via a bracket, the bracket attached to the wheelchair and having a slot such that a leg of the connecting arm is received within the slot.
US11357676B1 Apparatus to load and unload a mobility device
An apparatus to load and unload a mobility device includes a base, a first actuating assembly, a second actuating assembly, a shuttle, and a lift arm assembly. The first actuating assembly and the second actuating assembly are oppositely positioned of each other about the base so that a linear actuator of the first actuating assembly and the second actuating assembly can rotatably mount to the base about a first rotational axis. Rotation of the linear actuators moves up and down the lift arm assembly as the linear actuator of the first actuating assembly and the second actuating assembly are rotatably mounted to the lift arm assembly about a second rotational axis. The shuttle that receives the mobility device is rotatably mounted to the lift arm assembly about a third rotational axis so that the mobility device can be loaded and unloaded from a cargo space of a transportation vehicle.
US11357674B2 Radially tensioned wound or skin treatment devices and methods
Devices, kits and methods described herein may be for treatment to skin, including but not limited to wound healing, the treatment, amelioration, and/or prevention of scars or keloids. An applicator and/or tensioning device may be used to apply a dressing to a subject. The applicator and/or tensioning device applies and/or maintains a strain in an elastic dressing, wherein at least some of the strain is out-of-plane or at a non-orthogonal, non-parallel and non-aligned orientation to other strains in the dressing.
US11357666B2 Method and apparatus for prediction of post-operative perceived iris color
The present invention predicts prior to a laser iris color-change procedure what a patient's iris color will be after the procedure. The present invention does so by identifying and measuring a variety of anatomical features of the patient's eye that affect or are otherwise relevant to predicting the patient's post-operative iris color, translating these measurements into a post-operative iris color prediction, and communicating this prediction to the patient in a manner sufficient to manage the patient's expectations with respect to the aesthetic outcome of the procedure.
US11357663B2 Non-contact, infrared sensing temperature-activated controller for abatement of effects of hot flashes in a human body
A directable, portable appliance in combination with an adjustable set-point digital temperature controller for non-contact remotely monitoring infrared temperatures of a selected area of human skin and activating an electrical fan for directing cooling air over the selected skin areas of individuals experiencing episodes of thermal chaos, i.e., hot flashes.
US11357661B2 Method for vacuum-forming dental appliance
An appliance and methods are described that include embodiments of a mandibular advancement or positioning device which can use elastic bands to pull the jaw forward. The appliance has an upper plastic tray conforming to the patient's upper teeth and including 3D printed sets of retention hooks coupled to the upper plastic tray via being encased in plastic, one on the right and one on the left anterior buccal portion of an upper plastic base. The appliance also has a lower plastic tray conforming to the patient's lower teeth including mandibular dentition, and includes having a 3D printed bite pad which opens the bite vertically. The lower tray also has a set of 3D printed plastic retention hooks encased in plastic extending outwardly from the teeth, one on the right and one on the left of the posterior buccal portion of the lower plastic base. Elastic bands of different lengths and strengths are attached to both the top and bottom retention hooks on both sides of the trays to pull the mandible forward for treatment.
US11357660B2 Implantable medical devices for tissue repositioning
A medical device for repositioning tissue within an animal has a main body with a first end portion, a second end portion, and a middle portion. The first end portion defines a series of passageways and the second end portion defines a bulbous shape, a slot, and a tab portion. Methods of treating obstructive sleep apnea are also described.
US11357658B2 Lid for medical implant
A lid for a medical implant that has first and second parts and a mechanism for engaging the implant. The second part is rotatable relative to the first part such that, in use, rotation of the second part relative to the first part causes the engaging mechanism to engage with and attach the lid to the implant.
US11357655B2 Custom headwear manufactured by additive manufacture
Custom manufactured headwear for a subject's head is provided. The headwear comprises an inner layer deposited by an additive manufacturing device. The headwear further comprises an outer layer deposited by the additive manufacturing device. The inner layer and the outer layer are each formed by the additive manufacture device utilizing a device data file derived from a subject data file. The subject data file is representative of the shape of the head and the device data file determining the shape of the headwear.
US11357653B2 Dorsiflexion assist device
A dorsiflexion (or eversion) assistance device attaches around an ankle and foot, such us over footwear. A tensioned cord is extended between a portion attached to the ankle and a portion attached to the foot. This tensioned cord is attached to one of a plurality of portals of a connector attached to the ankle and connector attached to the superior side of the foot depending on a need for greater assistance on a left, medial, or right side. The connector on the ankle can be a bearing movable or rotatable front/back, left/right and around so as to allow the tensioned cord to move as the wearer walks as well as angle the tensioned cord in a resting or walking state.
US11357647B2 Pump system
A prosthetic system includes a prosthetic foot having an upper foot element with a concave-forward facing portion and foot portion extending forwardly therefrom. An intermediate foot element is disposed below the upper foot element and has a front portion coupled to the foot portion of the upper foot element. A lower foot element is disposed below the intermediate foot element. A pump system is coupled to the prosthetic foot and comprises a pump mechanism including a housing defining a cavity, and a membrane situated in the cavity. The pump mechanism is movable between an original configuration and an expanded configuration. An arm member is connected to the pump mechanism and operatively coupled to the intermediate foot element. The arm member is arranged to move the pump mechanism toward at least the expanded configuration upon movement of the intermediate foot element relative to the upper foot element.
US11357645B2 Implant with graded radiopacity calibration feature
An implant device for use in achieving spinal fusion, includes an implant having an implant body. The device includes a graded radiopacity calibration tool integrated with the implant body. The tool has a plurality of graded levels of radiopacity representative of a range of bone density parameter amounts. Each of the graded levels corresponds to a different bone density parameter amount. A method is provided that uses the device to determine a degree of one of bone maturity, strength, osteoporotic state, state of healing and state of degrading bone tissue based on a comparison of a bone at the site in the image and radiopacity correlated from a calibration standardized curve defined by the standard, with a range of grey levels representative of degrees of one of the bone maturity, the strength, the osteoporotic state, the state of healing and the state of degrading bone tissue.
US11357640B2 Expandable interbody fusions devices
Expandable fusion devices, systems, instruments, and methods thereof. The expandable fusion implant may include an upper endplate assembly and a lower endplate assembly. The upper and lower endplate assemblies may be configured to expand in width. A rotatable actuator may move one or more driving ramps, which mate with an upper ramp and a lower ramp, respectively. The actuator may cause independent movement of one or more of the driving ramps, thereby causing an expansion in height of the upper and lower endplate assemblies.
US11357636B2 Magnetic artificial joint
The invention relates to a prosthesis for implantation into a living body in the form of a magnetic artificial joint, in particular an artificial shoulder joint, comprising: a) a first prosthesis member comprising a socket member, b) a second prosthesis member comprising a head member, c) one of the socket member and the head member is at least partially composed as a permanent magnet and the other one of the socket member and the head member is at least partially composed of a magnetic material, or the socket member and the head member are both at least partially composed as a permanent magnet, d) the socket member comprises a recess on a surface side to be coupled with the head member, the recess comprising a concavely contoured contact surface, e) the head member comprises a projection on a surface side to be coupled with the socket member, the projection comprising a convexly contoured contact surface, f) the convexly contoured contact surface is adapted to the concavely contoured contact surface, such that the head member can be coupled in a rotatably jointed manner to the socket member in the nature of a ball/ball-socket joint, g) wherein the convexly contoured contact surface can perform a generally slip-fee rolling motion or a combined slipping and rolling motion on the concavely contoured contact surface in reaction to a change of an angle between the first and the second prosthesis member, and the convexly contoured contact surface can be shifted across the concavely contoured contact surface within a shifting area.
US11357623B2 Decalcifying heart valve
Vascular valve systems for treating calcified vascular vessel valves by delivery of one or more calcium chelating agents are described. The vascular valve systems can include an expandable stent, a valve, and a material layer. The material layer includes a hydrogel, calcium chelating agent, and an acidifying agent. Methods of making the vascular valve systems are also described.
US11357622B2 Prosthetic valve for avoiding obstruction of outflow
A prosthetic mitral valve may be anchored in a native mitral valve. The prosthetic mitral valve preferably has a large anterior prosthetic leaflet that spans the entire width of the native anterior leaflet and the anterior prosthetic leaflet moves away from left ventricular outflow tract during systole to create a clear unobstructed outflow path.
US11357620B1 Exchangeable optics and therapeutics
An exchangeable optics system includes an intraocular base that can be fixed within an eye. The intraocular base includes one or more couplers and a supporting structure. The one or more couplers releasably couple to an exchangeable optic or therapeutic and can include magnetic material. The supporting structure can include haptics and a main structure that physically supports the exchangeable optic or the therapeutic that is coupled via the one or more couplers. In some cases, the intraocular base can include a fixed lens within or on the main structure. The exchangeable optic can include corresponding one or more couplers, which may be formed of magnetic material. The therapeutic can be in the form of a magnetic particle.
US11357611B2 Elastic stent graft
A stent graft including a stent having a wall having at least one opening, an outer surface, and an inner surface and a covering of a composite material having a least one expanded fluoropolymer membrane and an elastomer is provided. The cover can be used to cover the outer and/or the inner surface of the stent. The expanded fluoropolymer membrane contains serpentine fibrils. In exemplary embodiments, the fluoropolymer is polytetrafluoroethylene. The composite material may be axially and/or circumferentially wrapped around the stent. The composite material is fold-free throughout its operating diameter range and exhibits a sharp increase in stiffness at a predetermined diameter. The stent graft can be designed to have a stop point in either a radial or axial direction. The stent graft can advantageously be implanted undersized with respect to a nominal diameter without having material infolding.
US11357606B2 Reinforcing structure for coronal-radicular dental restoration, method for carrying out coronal-radicular dental restoration, and coronal-radicular restoration
A reinforcement structure for a crown and root tooth restoration includes: a plurality of reinforcement pins having diameters ranging from 0.1 mm to 0.5 mm, an etching canal facilitating access to an infected apex, in the crown and root restoration, a joining element configured to group the plurality of reinforcement pins together so as to form a bundle of pins, the joining element partially covering the length of the reinforcement pins.
US11357604B2 Artificial intelligence platform for determining dental readiness
A comprehensive dental readiness platform is presented. Dental patient data including an image, proposed treatments, and a dental form are received and processed by first machine learning models to obtain clinical findings and predicted values for fields of the dental form. The clinical findings and other results are processed by a second machine learning model to obtain predictions of a future dental condition of a patient. The second machine learning model utilizes an ensemble of Transformer Neural Networks, Long-Short-Term-Memory Networks, Convolutional Neural Networks, and Tree-Based Algorithms to predict the dental readiness classification, dental readiness durability, dental readiness error, dental emergency likelihood, prognosis, and alternative treatment options.
US11357601B2 Electronic impression tray for obtaining dental information
An electronic impression tray can be used to obtain three-dimensional and temporal measurements in dentistry. There is a device having optical measurement sensor system, and an electronic system including a central management unit capable of collecting, storing and ordering the data obtained by the sensor systems distributed over all or part of the impression tray. An optical impression of all or part of a dental arch can be obtained with a single or multiple impressions. The tray includes a part having the shape of all or part of a dental arch, and the part can change by virtue of its ability to deform and/or a structure formed by multiple elements that are hinged to one another and/or reversibly assembled and secured to one another, such as to provide the optimal shape.
US11357596B2 Medical holding arm for incorporation into a surgical navigation system
A holding device for medical purposes holds an attached device. The holding device has a proximal end for attaching the holding device to a base and a distal end for receiving the attached device. The holding device also has a first arm segment and a second arm segment. The first arm segment is connected to a first joint and the second arm segment is connected to a second joint. Each joint is releasable or lockable. The holding device further has an operator control device for releasing and/or locking the first or second joint for placing the holding device in a desired pose. The holding device also has a controller for controlling the holding device and at least one receiver for electromagnetic radiation connected to the controller for transmitting signals to the controller based on received electromagnetic signals of a surgical navigation system.
US11357595B2 Gross positioning device and related systems and methods
Disclosed herein are gross positioning systems for use with robotic surgical devices to provide gross positioning of the robotic surgical devices. The gross positioning systems have a base, a first arm link operably coupled to the base, a second arm link operably coupled to the first arm link, a third arm link operably coupled to the second arm link, and a slidable coupling component slidably coupled to the third arm link.
US11357594B2 Jig assembled on stereoscopic surgical microscope for applying augmented reality techniques to surgical procedures
A system includes a first optical assembly (OA), a second OA and a processor. The first OA and second OA each coupled with a first and second microscope eyepiece, respectively. Each first and second OAs including a light source, configured to direct an emitted light beam (ELB) through the microscope toward an organ, and an image sensor, configured to sense a reflected light beam (RLB), which is reflected from the organ through the microscope, and to produce a signal indicative of the RLB. The processor is configured to control the first and second OAs to alternately direct the ELB and sense the RLB at first and second time intervals, and alternately display on a first display, during the first time intervals, images based on the signal from the first OA, and display on a second display, during the second time intervals, images based on the signal from the second OA.
US11357591B2 Surgical instrument delivery systems and related methods
In one aspect of the present disclosure, a sterilization mat is provided that is configured to receive non-sterile surgical instruments, rolled to a rolled configuration, and sterilized while in the rolled configuration. In accordance with another aspect of the present disclosure, a specialized surgical supply kit includes a package that retains surgical supplies having at least one surgical supply identified as a preferred surgical supply by the hospital or surgeon that is to perform the surgery. The surgical supplies are further arranged in a spatial arrangement based on the surgeon who is to perform the surgery.
US11357586B2 Systems and methods for saturated robotic movement
Systems and methods for saturated robotic movement are provided. In one aspect, there is provided a robotic system, including a robotic arm configured to control movement of a medical instrument, and a processor configured to: receive a first user input from a user for moving the medical instrument with the robotic arm, determine that moving the robotic arm according to the first user input would cause a contact point of the robotic arm to contact or cross a collision boundary surrounding an object, and guide the movement of the robotic arm such that the contact point of the robotic arm continuously moves along the collision boundary based in part on the first user input, in response to the determination that moving the robotic arm according to the first user input would cause the contact point to contact or cross the collision boundary.
US11357578B2 Surgical instrument and method
A surgical instrument comprises a member connected with a spinal implant defining an axis. A first image guide is connected with the member and oriented relative to a sensor to communicate a signal representative of a position of the member. A second image guide is connected with the member and oriented to represent an angle measuring a second orientation of the axis relative to a first orientation. Systems, implants and methods are disclosed.
US11357572B2 Double universal joint
Surgical tools having a two degree-of-freedom wrist, wrist articulation by linked tension members, mechanisms for transmitting torque through an angle, and minimally invasive surgical tools incorporating these features are disclosed. An elongate intermediate wrist member is pivotally coupled with a distal end of an instrument shaft so as to rotate about a first axis transverse to the shaft, and an end effector body is pivotally coupled with the intermediate member so as to rotate about a second axis that is transverse to the first axis. Linked tension members interact with attachment features to articulate the wrist. A torque-transmitting mechanism includes a coupling member, coupling pins, a drive shaft, and a driven shaft. The drive shaft is coupled with the driven shaft so as to control the relative orientations of the drive shaft, the coupling member, and the driven shaft.
US11357570B2 Ablation catheter with fiber Bragg grating strain sensors
An ablation catheter for treating cardiac arrhythmias by ablating near pulmonary venous tissue is described. The ablation catheter includes a system of optical fibers containing respective fiber Bragg gratings (FBG) that are susceptible to changes in strain to thereby indicate to the physician the amount of force that the ablation head is exerting on the myocardial tissue during the ablation procedure. Optionally, the FBGs are used to indicate the exact orientation of the catheter and its ablation head inside the vasculature.
US11357568B2 Radiometric tissue contact and tissue type detection
Radiometric systems may comprise a radiometer, an antenna and a processor communicatively coupled together. The processor may provide a contact-focused output based on filtering or other processing of a raw radiometric output signal. The contact-focused output may facilitate determination of whether contact has been achieved and/or assessment of contact. A miniaturized reflectometer may be configured to determine an amount of reflected power from the antenna. The processor may be configured to determine a reflection coefficient of the reflected power determined by the reflectometer and to identify tissue type based on the reflection coefficient. Systems and methods for facilitating deeper temperature measurements of a radiometer are described.
US11357567B2 Oncological amelioration by irradiation and/or ensonification of tumor vascularization
Techniques are disclosed, including methods and systems/apparatus, that can be used to treat cancerous tissue by exploiting the fact that such tissues have vascular branching with fractal descriptions and fractal dimensions, which are different from those found in normal soft tissue vascular branching. Such fractal branching of diseased tissue can produce resonances, or preferential energy absorption, when irradiated by either ultrasound and/or radio frequencies of EM energy; these resonances are not shared by the vascularization in normal soft tissue. Accordingly, one or more specific arrangements of multiband radiation (e.g., RF and/or ultrasonic) used to irradiate such diseased tissue will cause heating and possibly localized necropsy of tumor blood vessels, with little or minimal damage to surrounding healthy tissue. Embodiments can utilize ablation devices in conjunction with RF and/or ultrasonic sources. Embodiments can further utilize chemotherapy (before, during, or after hyperthermic treatment) for enhancing cancer treatment.
US11357566B2 Medical instrument electrically energized using drive cables
An electrically energized medical instrument uses one or more drive cables to both actuate mechanical components of a wrist mechanism or an effector and to electrically energize the effector. Electrical isolation can be achieved using an insulating main tube through which drive cables extend from a backend mechanism to the effector, an insulating end cover that leaves only the desired portions of the effector exposed, and one or more seals to prevent electrically conductive liquid from entering the main tube. Component count and cost may be further reduced using a pair of pulleys that are shared by four drive cables.
US11357564B2 Electrosurgical device with vacuum port
An electrosurgical device comprising: an electrode having a first portion whose exterior is electrically uninsulated, a second portion whose exterior is electrically insulated, and a third portion; an elongated hollow body having an internal cavity, a front end, a rear end, an external surface, and an electrical wire arranged within the body. The hollow body is configured to reversibly receive the third portion of the electrode at the front end of the body such that electrical contact is made between the electrode and the electrical wire and the second portion of the electrode is not surrounded by the hollow body. A first button is provided for controlling a current flow at a first level to the electrode and is arranged on the external surface. A vacuum tube is slidably engaged by the body and has an inlet generally facing the front end and adjacent the electrode. A vacuum outlet port is arranged near the rear end of the body, and the outlet port, internal cavity, and vacuum inlet are in fluid communication with each other.
US11357562B2 Instruments and method for use in disassembling implants
An orthopaedic surgical instrument for use in disassembling an orthopaedic prosthesis includes a main component, a rod, and a spindle. The main component has a housing and an elongated body extending from the housing with a passageway is defined in the elongated body. The rod has an elongated shaft, with a greater length than the elongated body, extending from the head of the rod and configured to pass through the main component. The spindle threads into the housing to move the rod along a longitudinal axis.
US11357559B2 Modular osteosynthesis device for vertebrae
An osteosynthesis device for the treatment of the spine is disclosed having a fork head which is U-shaped in a side view, and which fork head, in the proximal direction, has two fork legs with an internal thread and in which a connecting rod can be received, and a grub screw is passed through the internal thread, and the fork head is detachably connected to a bone anchor. The bone anchor is pivotably mounted in the ball seat of the fork head, wherein the fork head in the ball seat area has slots open towards the distal side and thereby at least one deflectable leg is formed.
US11357558B2 Drill wire sleeve
A drill wire sleeve includes a tubular oblong sleeve having a length, an internal diameter and an external diameter. The drill wire sleeve has a first axial end cap and a second axial end cap. The first axial end cap and/or the second axial end cap is detachably fastenable without tools on the tubular oblong sleeve using a thread and detachably closes an insertion opening of the tubular oblong sleeve. The first axial end cap and/or the second axial end cap has a non-rotationally symmetrical outer cross section and the tubular oblong sleeve has a plurality of first passages in its lateral surface. The first passages are formed oblong and are inclined at an angle of 25° to 65° in relation to the longitudinal axis of the tubular oblong sleeve, preferably at an angle of 28° to 55°, and more preferably at an angle of 31° to 52°.
US11357555B2 Bone fastening device having plates and screws
A bone fastening device includes a ready-to-assemble plate assembly including hingedly secured first, second, third, and fourth plates, first insertion members, second insertion members, a plurality of upper half adjustment members, and a plurality of lower half adjustment members; and a plurality of screws configured to drive through the first, second, third, and fourth plates into the broken bone.
US11357554B2 Clavicle fixation system
Clavicle fixation devices and methods thereof. A clavicle fixation device includes an elongated plate extending between first and second ends, the elongated plate defining a plurality of spaced apart screw holes. At least one pair of relief cuts extends into the elongated plate on opposite sides thereof, the at least one pair of relief cuts axially positioned between a pair of the spaced apart screw holes and at least one pair of suture holes along opposite sides of the elongated plate, the at least one pair of suture holes axially positioned between a pair of the spaced apart screw holes. At least one pair of relief cuts is axially aligned with a pair of suture holes to define combined holes on opposite sides of the elongated plate.
US11357552B2 Devices and methods for inserting a vertebral fixation member
Devices, systems, and methods for inserting a vertebral stabilization member, such as a rod. The insertion device includes an outer guide tube, a pin assembly including a pin and a pusher member extending therethrough. The insertion device is configured to actuate a rod between a first orientation and a second orientation angled with respect to the first orientation in order to position the rod in an appropriate location for attachment to bone.
US11357551B2 Bi-directional fixating transvertebral body screws, zero-profile horizontal intervertebral miniplates, total intervertebral body fusion devices, and posterior motion-calibrating interarticulating joint stapling device for spinal fusion
An apparatus and method for joining members together using a self-drilling screw apparatus or stapling apparatus are disclosed. The screw apparatus includes a worm drive screw, a spur gear and superior and inferior screws which turn simultaneously in a bi-directional manner. A rotating mechanism drives the first and second screw members in opposite directions and causes the screw members to embed themselves in the members to be joined. The screw apparatus can be used to join members such as bones, portions of the spinal column, vertebral bodies, wood, building materials, metals, masonry, or plastics. A device employing two screws (two-in-one) can be combined with a capping horizontal mini-plate. A device employing three screws can be combined in enclosures (three-in-one). The stapling apparatus includes grip handles, transmission linkages, a drive rod a fulcrum and a cylinder. The staple has superior and inferior segments with serrated interfaces, a teethed unidirectional locking mechanism and four facet piercing elements. The staples can be also be used to join members such as bones, portions of the spinal column, or vertebral bodies.
US11357546B2 Device for enabling placement of intra-osseous infusion tools in the upper extremity
Survival of patients suffering from many infections diarrheal diseases, including Ebola, as well as trauma and post-partum hemorrhage is improved with large-volume, parenteral, fluid replacement. In lieu of IVs, Intra-Osseous (IO) lines are placed with the help of a Humerus-Finder™, a one-piece guide that identifies the humeral head at the shoulder and allows for easy, safe, placement of an IO line. This guide enables healthcare providers and lay-providers to place IO lines and deliver fluids to infected persons without direct contact, limiting risk to providers. The Humerus-Finder™ makes early, potentially life-saving, supportive treatment available where large-volume fluid infusion can save lives and is useful in disaster medicine and emergency medicine when it is not possible to place an IV line rapidly and safely by helping first responders achieve IO access for delivery of fluid resuscitation in a safe, reliable manner.
US11357544B2 Systems and methods for introducing a stimulation lead into a patient
A lead-implantation tool for implanting a lead into a patient includes an elongated body having a distal portion with a tip configured to separate patient tissue to form, or extend through, a tunnel in the tissue when the body is advanced along the tissue. A lead-retention element is formed along the distal portion of the body and includes a cutout defined along the body with a cutout surface wall inset from the body's outer surface. A protrusion extends outwardly from the cutout surface wall with at least a portion of the protrusion extending towards the tip. The protrusion is entirely inset from, or flush with, the body's outer surface. The protrusion is configured to removably receive and retain a portion of the lead while the distal portion of the body is advanced along the tissue and to separate from the lead as the body is withdrawn from the tissue.
US11357539B2 Catheter devices, needle assemblies, kits and methods
Examples of catheter devices, removable needle devices and kits are disclosed. Also methods for accessing a hollow organ are disclosed. The catheter devices include a body extending longitudinally from a proximal end to a distal end, wherein the body includes an elongated channel along a longitudinal length of the body extending from the proximal end to the distal end of the body, wherein the channel is configured to receive an elongated needle of a removable needle device, and the body includes one or more cutting edges extending in a proximal direction from the distal end of the body. The body of the catheter device includes one or more recesses adapted to mate with one or more catches of the removable needle device for coupling the needle device to the catheter devices. Also methods of using the catheters, removable needle devices and the kits are disclosed.
US11357537B2 Prepuce extruding, cutting, hemostasis, and healing assembly using ultrasonic wave
A prepuce extruding, cutting, hemostasis, and healing assembly using ultrasonic wave. Ultrasonic wave is applied in extruding, cutting, hemostasis, and healing of prepuce at a conjunction of internal and external tissues of a distal part of a human body. The assembly includes an ultrasonic generating device, a transmission device and a circumcision device. The ultrasonic generating device is used for generating ultrasonic waves, is connected to the transmission device and can send the ultrasonic waves to the transmission device. The transmission device is connected to the circumcision device and can send the ultrasonic waves to the circumcision device. The circumcision device is used for extruding and cutting a prepuce and/or performing hemostasis and/or healing of wounds. In this way, circumcision can be completed within just several seconds, and immediate healing can be achieved, preventing bleeding during and after a surgery.
US11357536B2 Device and method for producing a micro-graft matrix from full-thickness skin
A device set and a method for producing a micro-graft matrix with a plurality of punched full-thickness skin parts (12) from skin includes a film set of at least one first film (1) and one second film (2), which adhere to and are peelable from one another; an adhesive (10) to stick the first film (1) onto the skin; a cutting device with an adapter to provide a predefined distance to the skin and to make a plurality of hollow-cylindrical cuts vertical to the film set down to a predetermined depth in the skin underneath, the film set being respectively cut and divided, so that an outer portion of the second film can be peeled off and inner portions remain; and a third film (3), stuck in contact with the second film (2). The punched full-thickness skin parts can be extracted from the skin as the micro-graft matrix using the third film (3).
US11357534B2 Catheter
A catheter can restore the patency of a body lumen, for example, by removing tissue from a body lumen (e.g., a blood vessel). The catheter can be a rotational catheter having a rotatable drive shaft and a tissue-removing element secured to the drive shaft to be driven in rotation by the drive shaft. The catheter can have an abrasive burr configured to abrade tissue in a body lumen. The catheter can have an expandable tissue-removing element. The catheter can include a balloon and an inflation conduit. The catheter can also be configured to move over a guidewire through a body lumen. In one embodiment, the catheter comprises an over-the-wire, balloon-expandable, rotational, and abrasive tissue-removing catheter.
US11357519B2 Cutting guide for periacetabular osteotomy and kit for periacetabular osteotomy
A cutting guide for periacetabular osteotomy comprises at least one first main body having a longitudinal opening for the insertion of a cutting instrument, extending from a first end to a second end of the first main body and at least two positioning and fixing arms extending away from the first main body from opposite sides with respect to the longitudinal opening, in order to correctly position the first main body on a bone and fix it thereto through respective fastening members.
US11357516B2 Abrasive cutting surgical instrument
Surgical tools for removal of tissue, namely instruments, devices and methods for surgical tissue cutting with a cylindrical cutting burr bit extending from an elongated hollow member and connected to a shaft for actuating rotation motion of said burr bit to cut/remove tissue from a target location, while mitigating the harm of damaging surrounding tissue.
US11357509B2 Reload assembly for a circular stapling device
A reload assembly includes a shell housing, a staple cartridge, a staple actuator, and a knife carrier. In embodiments, the knife carrier or the shell housing defines a locking groove and the other of the knife carrier and the shell housing supports a locking member. In other embodiments, the knife carrier or the staple actuator defines a locking groove and the other of the knife carrier and the staple actuator supports a locking member. The locking member is received within and movable through the locking groove to prevent readvancement of the knife carrier after the reload assembly is fired.
US11357507B2 Surgical stapling device for performing circular anastomosis and surgical staples for use therewith
An anvil assembly, an end effector, and/or a surgical stapler are suitable for performing curved or circular anastomosis and/or treatment to internal walls of hollow tissue organs. The anvil assembly includes an anvil center rod and an anvil head secured to a distal end of the anvil center rod. The anvil head includes an anvil plate defining a tissue contact surface and a plurality of staple forming pockets formed in the tissue contact surface of the anvil plate. Each of the staple forming pockets defines an arcuate longitudinal axis.
US11357506B2 Device and method for assisting selection of surgical staple height
A compression gauge cartridge for use mounted in a cartridge bay of a cartridge jaw member of a surgical stapler instrument to compress a tissue consistently to a predetermined thickness and measure a reactionary load therefrom comprises: a cartridge body; a force gauge assembly comprising a force transducer and a compression head having a tissue compression ace, wherein the force gauge assembly is supported by the cartridge body, and wherein the compression head is configured and disposed so that the tissue compression face thereof lies substantially closer to the tissue contacting surface of the anvil jaw member than the tissue supporting surface of the cartridge body; and a spacer member extending from the tissue supporting surface of the cartridge body, wherein the force gauge assembly is positioned distally with respect to the spacer member.
US11357505B2 Surgical stapling apparatus with firing lockout mechanism
A surgical stapling device is provided which includes a first jaw supporting an anvil assembly and a second jaw supporting a cartridge assembly. The cartridge assembly supports a firing lockout assembly which includes a latch member having a blocking portion. The latch member is movable between a first position and a second position. In the first position, the blocking portion of the latch member is aligned with the stop surface of the drive member to prevent advancement of the drive assembly beyond an initial advanced position within the tool assembly and in the second position, the blocking member is misaligned with the stop surface of the drive member to permit subsequent advancement of the drive assembly within the tool assembly. In the retracted position of the drive assembly subsequent to firing of the surgical stapling device, the latch member is in the first position.
US11357501B2 Braided filament having flat morphology and methods of manufacture and use
A braided filamentary device, in one embodiment, includes a substantially flat morphology having a length, a width, and a height, and a pick count of at least about 50 picks per inch. The filamentary device is adapted to maintain its width while under a tension.
US11357500B2 Surgical suturing device for repair of tricuspid regurgitation and methods thereof
A surgical suturing device is disclosed. The surgical suturing device may include a first or a second tissue gap, a first pair of needles configured to be movable across the first tissue gap, a second pair of needles configured to be movable across the second tissue gap, and a first suture having first and second ends. The surgical suturing device also includes a second suture having first and second ends and a needle actuator which selectively engages either: the first pair of needles to drive them through the first tissue gap and into communication with the first end of the first suture and the first end of the second suture, respectively; or the second pair of needles to drive them through the second tissue gap and into communication with the second end of the first suture and the second end of the second suture.
US11357499B2 Apparatus for mitral valve repair and methods thereof
A surgical snare assembly is disclosed. The surgical snare assembly has a suture fastener having an entrance and an exit. The surgical snare assembly also has first and second suture engaging loops. The surgical snare assembly further has first and second handles configured such that: a) movement of the first handle a first distance away from the suture fastener causes the first suture engaging loop to move through the suture fastener from the exit to the entrance; and b) movement of the second handle a second distance away from the suture fastener causes the second suture engaging loop to move through the suture fastener from the entrance to the exit.
US11357495B2 Tissue augmentation scaffolds for use with soft tissue fixation repair systems and methods
Devices, systems, and methods to improve both the reliability of soft tissue repair procedures and the speed at which the procedures are completed are provided. The devices and systems include one or more tissue augmentation constructs, which include constructs that are configured to increase a footprint across which suture applied force to tissue when the suture is tied down onto the tissue. The tissue augmentation constructs can be quickly and easily associated with the repair suture, and can be useful in many different tissue repair procedures that are disclosed in the application. In one exemplary embodiment, one or more constructs are disposed on a suture threader, which can be used to associate the construct(s) with a repair suture(s) being used to repair the soft tissue. Tissue augmentation constructs can include various blocks and patches, among other formations. Exemplary methods for manufacturing the tissue augmentation constructs are also provided.
US11357489B2 Spinal nerve decompression systems, dilation systems, and methods of using the same
A method for treating spinal nerve compression includes sequential dilation to position an instrument cannula along a patient's spine. Instruments can be delivered through the instrument cannula to remove targeted tissue for a decompression procedure. One of the instruments can be a reamer instrument configured to abrade, cut, or otherwise affect tissue along the patient's spine.
US11357483B2 Surgical instrument with flexible shaft and actuation element guide
A surgical instrument includes a shaft, a force transmission mechanism disposed at a first end of the shaft, an end effector disposed at a second end of the shaft, an actuation element that extends along the shaft from the force transmission mechanism to the end effector, and an actuation element guide extending along the shaft. The actuation element guide defines a lumen in which the actuation element guide is received. The actuation element guide is compressed into a pre-compressed state along at least a portion of an axial length of the shaft. The actuation element guide can be compressed between first and second blocks of the instrument. The instrument can include a flush tube configured to receive a cleaning fluid, with the actuation element guide being in flow communication with the flush tube to receive the cleaning fluid in the lumen of the actuation element guide.
US11357481B2 Devices and methods for aiding conception
A conception aid for assisting in natural conception may include a platform configured for placement in a vaginal canal, wherein the platform comprises one or more capturing elements configured to collect semen. A method of aiding conception may include providing a conception aid device including one or more capturing elements, collecting semen with the one or more capturing elements wherein the one or more capturing elements is configured to contain the collected semen on the device, and positioning the device in a vaginal canal.
US11357477B2 Microbubble destruction for medical ultrasound imaging
By identifying locations of contrast agent response, an intensity-based metric of contrast agent signal is used to control a duration of microbubble destruction with a medical ultrasound scanner. Feedback from motion of the transducer may be used to indicate when a user perceives enough destruction. A combination of both an intensity-based metric and transducer motion may be used to control the duration of bursting.
US11357475B2 Device and method for ultrasound examination
With a device and an associated method, an ultrasound unit is coupled with a coupling unit to an existing x-ray unit. The ultrasound unit is guided with the aid of controllable elements of a positioning unit of the x-ray unit on a patient for an ultrasound examination. In this manner X-ray recordings and ultrasound recordings of an object can be produced.
US11357474B2 Method of quantitative analysis and imaging of the anterior segment of the eye
What is provided are methods of analyzing at least one image of the anterior segment of an eye and for selecting an intraocular lens (IOL). The methods may include detecting at least one image from an anterior segment of the eye; identifying a location of a reference structure on the eye using a plurality of points of a landmark on the anterior segment of the eye; and calculating at least one quantitative dimension of the anterior segment of the eye using the reference structure. The newly identified landmarks and quantifiable dimensions improve the characterization of the anterior segment in order to better predict the position and movement of the intraocular lens. The improved methods for analyzing the imaging of the anterior segment of the eye allows for improvements in the refractive outcomes of cataract surgery, glaucoma procedures, refractive outcomes, and other eye-related diseases.
US11357473B2 Path tracking in ultrasound system for device tracking
A method for determining a projected track of an object (230) includes measuring movement from frame to frame of a detected object point in a field of view by periodic comparison of positions, extrapolating a locus of periodically detected object points, and qualifying the locus by calculating and applying a threshold to the linearity in a sequence of positions and a threshold to consistency in strength. The method further produces the plurality of ultrasound images by including thereon a rendering of a plurality of lines (310) as a path track indicator (330) on one or more ultrasound images (305) and displaying the projected track of the object when a user moves the tracked object a minimum distance in a region of interest (242) of a subject (240). The method also includes utilizing a motion sensor (234) with a probe (205) to suppress calculation and display of the projected track.
US11357468B2 Control apparatus operatively coupled with medical imaging apparatus and medical imaging apparatus having the same
The medical imaging apparatus includes a scanner configured to scan the object to image the internal area of the object; a patient table configured to convey the object to the scanner; an imager which is mounted on the scanner and configured to capture an image of the object on the patient table; and a mobile display device configured to display the image of the object captured by the imager.
US11357463B2 Target site selection, entry and update with automatic remote image annotation
Fluoroscopic imaging of a patient's heart is performed by positioning a patient in a sterile field and imaging the heart using a x-ray fluoroscopy system within the sterile to produce a two-dimensional image. The two-dimensional image is simultaneously displayed on an operative display within or adjacent the sterile filed and on a display of a remote image processor outside the operative field. The two-dimensional image of the remote display is manually marked or annotated to show anatomical or treatment information which is simultaneously shown on the operative display.
US11357459B2 Radiation imaging apparatus configured to receive a power in a non-contact manner, radiation imaging system, radiation imaging method, and computer-readable medium
The radiation imaging apparatus according to the present invention is a radiation imaging apparatus arranged to detect radiation and receive power in a non-contact manner, the radiation imaging apparatus including a control unit configured to stop at least one of the non-contact power reception of and the non-contact power supply to the radiation imaging apparatus depending on the state of the radiation imaging apparatus.