Document Document Title
US11339412B2 Metabolic engineering for microbial production of terpenoid products
In various aspects and embodiments, the invention relates to bacterial strains and methods for making terpene and terpenoid products. The invention provides bacterial strains with improved carbon flux through the MEP pathway, to thereby increase terpene and/or terpenoid product yield by fermentation with carbon sources such as glucose.
US11339411B2 Process to prepare elemental sulphur
The invention is directed to a process to prepare elemental sulphur by (i) contacting an aqueous solution comprising bisulphide with oxidised sulphide-oxidising bacteria under anaerobic conditions wherein elemental sulphur is produced and a reduced sulphide-oxidising bacteria is obtained and (ii) wherein the reduced sulphide-oxidising bacteria are oxidised by transfer of electrons to an anode of an electrochemical cell to obtain the oxidised sulphide-oxidising bacteria.
US11339406B2 Acid-alpha glucosidase variants and uses thereof
The present invention relates to variants of acid-alpha glucosidase and uses thereof.
US11339400B2 Systems, methods, and compositions for high-level production of water-soluble cannabinoids in a plant trichome
The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
US11339397B2 Expression of phytase in Aspergillus niger
Disclosed herein is a method for expressing phytase in a filamentous fungus by using an optimized Escherichia coli phytase gene having a nucleotide sequence as shown in SEQ ID NO. 7 and a signal peptide having a nucleotide sequence as shown in SEQ ID NO. 12.
US11339395B2 RNA-based regulatory technologies for miRNA sensors
Provided herein are genetic circuits and cell state classifiers for detecting the microRNA profile of a cell. In some embodiments, the cell state classifiers described herein utilize an endoribonuclease and a self-amplifying RNA molecule for controlling the expression of an output molecule. In some embodiments, the cell state classifiers described herein are encoded on a single RNA transcript, which is then processed to produce individual genetic circuits that function independently. The genetic circuits and cell state classifiers described herein may be used in various applications (e.g., therapeutic or diagnostic applications).
US11339386B2 Endolysin polypeptide
The invention relates to the field of medicine, specifically to the field of treatment of conditions associated with Staphylococcus infection. The invention relates to a novel endolysin polypeptide specifically targeting a bacterial Staphylococcus cell. The invention further relates to said endolysin polypeptide for medical use, preferably for treating an individual suffering from a condition associated with Staphylococcus infection.
US11339383B2 G proteins
The invention provides a mutant of a parent heterotrimeric G protein alpha (Gα) subunit, which mutant (i) lacks at least one helix of the helical domain of the parent Gα subunit; (ii) is capable of binding to a GPCR in the absence of a heterotrimeric G protein beta (Gβ) subunit and a heterotrimeric G protein gamma (Gγ) subunit; and (iii) has an amino acid sequence that contains one or more mutations compared to the amino acid sequence of the parent heterotrimeric Gα subunit, which mutations are selected from a deletion, a substitution and an insertion.
US11339381B2 Nucleotide sequence encoding 9-lipoxygenase and recombinant constructs comprising the same
The present invention provides a polynucleotide having the nucleotide sequence as set forth in SEQ ID NO: 1 encoding 9-lipoxygenase. The present invention also provides recombinant plasmid expression vector comprising said polynucleotide. The recombinant protein 9-lipoxygenase encoded by the polynucleotide leads to production of lactones in fruits such as mangoes.
US11339379B2 Malate dehyrogenases
The present invention relates to a recombinant host cell which is capable of producing a dicarboxylic acid and which comprises a mutant malate dehydrogenase resulting in an increased production of the dicarboxylic acid. The invention also relates to a process for producing a dicarboxylic acid, which method comprises fermenting said recombinant host cell in a suitable fermentation medium and producing the dicarboxylic acid.
US11339377B2 SO3 chromatography for use in a method for virus purification
The present invention refers to a process for purifying virus particles from cell culture, comprising the steps of subjecting the cell culture to centrifugation to get a supernatant fraction of virus particles, incubating said fraction with a nuclease, diluting the fraction with low conductivity buffer, subjecting said diluted fraction to a SO3 chromatography step, performing a washing step with low conductivity buffer, and eluting virus particles.
US11339376B2 Stable production of virulent enterovirus 71 and use thereof
Provided is a host cell for stably propagating a virulent hand, foot and mouth disease virus, the host cell expressing no heparan sulfate and overexpressing primate scavenger receptor class B member 2 (SCARB2). Also provided is a method for screening for an anti-hand, foot and mouth disease virus vaccine or an anti-hand, foot and mouth disease virus drug using a stably cultured virulent hand, foot and mouth disease virus.
US11339375B2 Paramyxovirus virus-like particles as protein delivery vehicles
Provided are modified virus-like particles (VLPs) of paramyxoviruses, compositions containing them, methods of using the VLPs for delivery of any particular protein of interest to any of a variety of cells, kits that contain expression vectors for making, using and detecting VLPs, and methods for screening for anti-viral compounds using the VLPs. The modified VLPs contain a contiguous recombinant polypeptide that contains i) all or a segment of a C-terminal domain of a paramyxovirus nucleocapsid protein and ii) a polypeptide sequence of a distinct protein. Non-covalent complexes of paramyxovirus M protein and fusion proteins that contain a C-terminal domain of a paramyxovirus nucleocapsid protein and a polypeptide sequence of a distinct protein are provided, as are non-covalent complexes of cells, and cell receptors, with modified VLPs.
US11339374B2 Assay and medicament
The invention relates to defective interfering viruses and defective interfering virus RNAs that are effective as antiviral agents. The invention also relates to methods for identifying defective interfering virus RNAs that can be used as effective antiviral agents.
US11339373B2 Method for producing adult liver progenitor cells
Novel adult liver progenitor cells (called H2Stem Cells) have been have been characterized on the basis of a series of biological activities and markers. Methods for producing H2Stem Cells allow providing such cells in the form of adherent cells and three-dimensional cell clusters in suspension that can be differentiated into cells having strong liver-specific activities and/or that can be used for treating liver diseases or for evaluating the efficacy, the metabolism, and/or toxicity of a compound.
US11339370B2 Cell line with METTL3 gene knocked out, its construction method and interference vector
A pig intestinal tract epithelium cell line with METTL3 gene knocked out and a construction method therefor. A gene interference vector for METTL3 form a pig is also provided.
US11339369B2 Production of parthenogenetic stem cells and patient-specific human embryonic stem cells using somatic cell nuclear transfer
Immunocompatible pluripotent stem cells (pSCs), which include cells compatible with different patient populations or patient-specific cells, find wide application in regenerative medicine therapies. Described herein are immunocompatible pSCs generated using techniques such as parthenogenesis resulting in cells possessing desired haplotypes of reduced zygosity, antigenically compatible with multiple patient populations, or nuclear transfer allowing generation of patient-specific cells. Methods described herein related to parthenogenesis, nuclear transfer, or pSC cell line generation. Also described herein are compositions of immunocompatible pSCs and cell lines generated by the aforementioned techniques.
US11339367B2 Hyperblebbing Shigella strains
Hyperblebbing Shigella strains are generated by disrupting one or more components of the Tol-Pal system. The blebs from these strains are useful immunogens for vaccination. The individual proteins found in these blebs can also be used as immunogens.
US11339366B2 Methods of performing nucleic acid stabilization and separation
Methods are provided for the stabilization and separation of nucleic acids from a sample via contact of the sample with a lysis and stabilization reagent that includes a cationic detergent. The cationic detergent lyses cells in the sample and stabilizes the released nucleic acids via the formation of nucleic acid-surfactant (NAS) complexes. The NAS complexes are centrifugally precipitated, washed, the resuspended in an aqueous resuspension liquid, forming a NAS complex suspension. The suspension is thermally processed to disintegrate the NAS complexes, thereby releasing the nucleic acids and forming a nucleic acid solution. In some example embodiments, the aqueous resuspension liquid is selected to be suitable for performing molecular amplification assays, such that the nucleic acid solution may be employed for performing a molecular amplification assay in the absence of further nucleic acid extraction. Examples are provided whereby the present methods are adapted for performing transcriptomic biomarker assays.
US11339364B2 Micro alternating tangential flow perfusion filter, micro bioreactor, and methods of use thereof
A micro alternating tangential flow (microATF) perfusion filter includes a hollow cylinder having a proximal end and a distal end. The proximal end is connected in series to a permeate chamber, followed by a retentate chamber. The proximal end either (i) terminates in or at the permeate chamber, or (ii) terminates in or at the retentate chamber. The portion of the proximal end within the permeate chamber, in a case of (ii), possesses at least one opening allowing fluid communication between an inside of the hollow cylinder and the permeate chamber. The microATF perfusion filter further includes an inlet, positioned over the retentate chamber, for communication with a source of positive or negative pressure, and an outlet, positioned in a wall of the permeate chamber, which can be connected to a check valve, which, in turn, can be connected to a hydrophobic fluid vent filter.
US11339359B2 Method for rapid maturation of distilled spirits using light and heat processes
An improved system and process for rapidly producing distilled spirits having characteristics associated with a much longer maturation process is provided. The method involves contacting wood with an unmatured distilled spirit under heated conditions and contacting the resulting heat-treated spirit with actinic light. The disclosure provides embodiments where a spirit is sequentially processed through heat and actinic light treatment. The disclosure also provides embodiments where a heat-treated spirit is mixed with a spirit that has been separately treated with light to give characteristics of a mature spirit. Air may also be percolated through a mature spirit in a container with a headspace at a gauge pressure between about −25 inHg and about −30 inHg, until the alcohol concentration of the mature spirit is reduced by between about 1% to about 2% by volume, and until the total volume of the mature spirit is reduced by about 10% or less.
US11339357B2 Sustainable laundry sour compositions with iron control
Linen treatment compositions and linen processes are disclosed which help to prevent iron deposition from wash water, and/or redeposition after iron containing stain (such as blood) removal by alkaline detergents. The linen treatment composition is a combination of a hydroxycarboxylic acid and an acid source, which may be organic or inorganic. The invention provides for effective iron control in a phosphorus-free formula that is also free of toxic or hazardous chemicals and includes sustainable, environmentally friendly ingredients, while still providing effective iron control.
US11339355B2 Glycosyl hydrolases
The invention relates to polypeptides having hydrolytic activity and polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides.
US11339351B2 Method for producing polyhydroxyalkanoate
A free fatty acid-containing substance, which is a waste liquid or by-product obtained in a process for producing palm oil or which is a hydrolysate of the waste liquid or by-product, is subjected to distillation treatment to obtain a free fatty acid fraction satisfying the requirements (i), (ii) and (iii), and a polyhydroxyalkanoate-producing microorganism is cultured in a culture solution containing the free fatty acid fraction. (i) The content of squalene is 0.05 wt % or less. (ii) The ratio of a peak area of trimethylindene to a peak area of a naphthalene-d8 standard is 110 or less in first-dimensional dynamic headspace-GC/TOFMS analysis. (iii) The ratio of a peak area of butyric acid to a peak area of a naphthalene-d8 standard is less than 10 in first-dimensional dynamic headspace-GC/TOFMS analysis.
US11339350B2 Process for producing free fatty acids
A process for producing free fatty acids from oil containing chlorophyll is disclosed. Exemplary processes include blending oil containing chlorophyll with fats, followed by hydrolysis and distillation.
US11339347B2 Blown and stripped blend of soybean oil and corn stillage oil
A method for producing a high viscosity, low volatiles blown stripped oil blend is provided. The method may include the steps of: (i) obtaining an oil blend of corn stillage oil and soybean oil having a weight ratio of corn stillage oil to soybean oil of from about 1:2 to 3:1; (ii) heating the oil blend to at least 90° C.; (iii) passing air through the heated oil blend to produce a blown oil having a viscosity of at least 50 cSt at 40° C.; and (iv) stripping the blown oil from step (iii) to reduce an acid value of the blown oil to less than 5.0 mg KOH/gram.
US11339335B1 Solvent deasphalting dearomatization process for heavy oil upgradation
An aspect of the present disclosure relates to a process for solvent deasphalting dearomatization, said process including: effecting deasphaltenation of a heavy oil feed by contacting the feed with a paraffinic rich solvent, optionally, in presence of a FCC catalyst to obtain a deasphalted oil rich stream, said paraffinic rich solvent being untreated naphtha; contacting the DAO rich stream with a second solvent to obtain a raffinate stream rich in non-asphaltene and non-aromatic contents and a solvent rich stream; contacting the raffinate stream with water in a first decanter to obtain a first stream rich in aromatic-lean fraction and a second stream rich in the second solvent and water; subjecting the first stream to distillation to recover the paraffinic rich solvent and to obtain deasphalted oil; contacting the solvent rich stream with water in a second decanter to obtain an aromatic rich fraction and a third stream rich in the second solvent and water; and subjecting the second stream and the third stream to distillation to recover the second solvent and water.
US11339332B2 Systems and processes integrating fluidized catalytic cracking with metathesis for producing olefins
Processes for producing olefins include introducing a hydrocarbon feed to a high-severity fluidized catalytic cracking system, contacting the hydrocarbon feed with a cracking catalyst under high-severity conditions in the high-severity fluidized catalytic cracking system to produce a cracking reaction effluent comprising butene, and passing at least a portion of the cracking reaction effluent, which includes at least butene, to a metathesis system. The processes further include contacting the portion of the cracking reaction effluent with a metathesis catalyst in the metathesis system, which causes at least a portion of the butene in the cracking C4 effluent to undergo a metathesis reaction to produce a metathesis reaction effluent comprising at least one of ethylene, propene, or both. The processes may further include separating a metathesis C5+ effluent from the metathesis reaction effluent and passing the metathesis C5+ effluent back to the high-severity fluidized catalytic cracking unit.
US11339327B2 Preparation of nanoparticle materials
A method of producing nanoparticles comprises effecting conversion of a molecular cluster compound to the material of the nanoparticles. The molecular cluster compound comprises a first ion and a second ion to be incorporated into the growing nanoparticles. The conversion can be effected in the presence of a second molecular cluster compound comprising a third ion and a fourth ion to be incorporated into the growing nanoparticles, under conditions permitting seeding and growth of the nanoparticles via consumption of a first molecular cluster compound.
US11339326B2 Tl+-based and mixed halide A3B2X9-type scintillators
Inorganic halides (e.g., inorganic halide scintillators) of the general formula A3B2X9, including inorganic halides comprising thallium monovalent cations and/or combinations of different halides, are described. Radiation detectors including the inorganic halide scintillators and methods of using the detectors to detect high energy radiation are also described. In some cases, the scintillators can include a gadolinium cation, a boron cation, a lithium cation, a chloride ion, or combinations thereof and the scintillator can be used to detect neutrons.
US11339325B2 Phosphor particle, composite, light-emitting device, and method for producing phosphor particle
An α-sialon phosphor particle containing Eu. At least one slit is formed on a surface of the α-sialon phosphor particle. The α-sialon phosphor particle is preferably produced by undergoing a raw material mixing step, a heating step, a pulverizing step, and an acid treatment step.
US11339320B2 Thiol-formyl hemiacetal corrosion inhibitors
The present invention generally relates to compositions and methods for inhibiting corrosion at a surface in the production, transportation, storage, and separation of crude oil and natural gas.
US11339316B1 Method and device for preparing graphene-based polyethylene glycol phase change material
A method and device for preparing a graphene-based polyethylene glycol phase change material. The method includes: (S1) dispersing carbon black in deionized water to form a carbon black dispersion; immersing polyurethane sponge in the carbon black dispersion; and taking out polyurethane sponge followed by drying to obtain a polyurethane sponge-carbon black combination; (S2) subjecting the polyurethane sponge-carbon black combination to a first electrical discharge machining to obtain a first intermediate; (S3) ultrasonically mixing the first intermediate, polyethylene glycol, and MgO to obtain a second intermediate; (S4) subjecting the second intermediate to a second electrical discharge machining to obtain a third intermediate; (S5) subjecting the third intermediate to acid washing to obtain a fourth intermediate, and drying the fourth intermediate; (S6) injecting polyethylene glycol into the fourth intermediate followed by stirring in a mold and drying to prepare the graphene-based polyethylene glycol phase change material.
US11339313B2 Adhesive
Provided is an adhesive that effectively utilizes bark and demonstrates superior adhesion performance. The adhesive of the present invention comprises at least one adhesive resin (A) selected from the group consisting of phenolic resin, urea resin, and melamine resin, and finely pulverized bark (B) comprising cellulose nanofibers.
US11339307B2 Solvent-containing emulsified alkyd resin coating compound for stain and varnish coatings
A solvent-containing coating compound for stains and varnish coatings, in particular for house varnishes or components thereof, containing or consisting of at least one oxidatively drying organic binder, selected from the group consisting of at least one oxidatively drying middle oil and/or long oil alkyd resin, in particular an oxidatively drying long oil alkyd resin, at least one primary drier based on iron, in particular comprising or consisting of at least one organic salt of iron and/or a coordination complex of iron, in particular a complex salt of iron, at least one first secondary drier, in particular comprising or consisting of at least one organic and/or inorganic salt or a compound of zirconium, magnesium, calcium, strontium, barium, zinc, lithium or aluminium, solvent, water, at least one emulsifying agent, optionally, at least one conventional additive.
US11339306B2 Active energy ray-curable coating composition
An object of the present invention is to provide an active energy ray-curable coating composition including a specific resin component and at least one pigment (D) selected from the group consisting of a coloring pigment and a glitter pigment. The present invention provides an active energy ray-curable coating composition including a poly[(meth)acryloyloxyalkyl] isocyanurate (A); a polyfunctional (meth)acrylate (B) having 4 or more (meth)acrylate groups; an acrylic resin (C); and at least one pigment (D) selected from the group consisting of a coloring pigment and a glitter pigment, wherein the acrylic resin (C) has a weight-average molecular weight in the range of 5,000 to 30,000 and a solubility parameter in the range of 9.0 to 11.5.
US11339304B2 Polymer emulsion as binder for conductive composition
Provided herein are metal conductive compositions with improved conductivity. The improved conductivity is attributable to the addition of a sintering agent and a polymer emulsion.
US11339299B2 Method of making oil repellent sheet material and gas sensor
A method of making an oil repellent sheet material according to an embodiment of the present disclosures includes a step of applying to a porous sheet a composition for forming an oil repellent layer, the composition containing a solvent and an amorphous fluorine resin dispersed therein, and a step of swaging the porous sheet after the step of applying, wherein the porous sheet has a fibrous skeleton composed mainly of polytetrafluoroethylene, the method of making an oil repellent sheet material further comprising a heat treatment step of heating the porous sheet to which the composition for forming an oil repellent layer is applied, before or after the step of swaging.
US11339294B2 Nanoprobe-metal chelator complexes
Provided herein are compounds that are able to bind metal ions (e.g., free metal ions or metal ions bound to low affinity ligands) in a sample or subject. Also provided herein are methods of using the compounds for chelating metal ions and for the treatment of diseases associated with abnormal levels of metal ions. Methods of preparing the compounds and pharmaceutical compositions are also provided.
US11339292B2 Flame-retardant, moisture-cured wire and cable constructions with improved glancing impact performance
Articles made from a moisture-curable, polymeric composition comprising in weight percent based on the weight of the composition: (A) 2 to less than 80 weight percent (wt %) of an ethylenic polymer with (1) a crystallinity at room temperature of 34% to 55%, or 65% to 80%, and (2) a melt index (I2) of 0.1 to 50 decigrams per minute (dg/min); (B) 3 to 30 wt % of a halogenated flame retardant; (C) 3 to 30 wt % an inorganic antimony flame retardant; and (D) 0 to 10 wt % of at least one of an inorganic flame retardant other than the inorganic antimony flame retardant, e.g., zinc oxide exhibit enhanced ACBD properties in comparison to articles alike in all respects except made from a composition comprising an ethylenic polymer without the requisite crystallinity at room temperature.
US11339284B2 Resin composition, cured product, formed body and manufacturing method thereof, and film capacitor and manufacturing method thereof
A resin composition for casting, containing a curable component, a first filler, and a second filler that is different from the first filler, in which a ratio of a major axis of the first filler with respect to a thickness of the first filler is 3 to 25. A molded body including an element and a sealing portion that seals the element, in which the sealing portion contains the resin composition or a cured product thereof.
US11339280B2 Polypropylene composition and molded article
A polypropylene composition made from or containing: (i) component (1) made from or containing a propylene/ethylene copolymer containing more than 1.5% by weight and not more than 4% by weight of an ethylene-derived unit; (ii) component (2) made from or containing an ethylene/propylene copolymer containing 65 to 87% by weight of an ethylene-derived unit; and (iii) 0.01 to 0.5 parts by weight of a crystal nucleating agent, based on a total of 100 parts by weight of component (1) and component (2); wherein the polypropylene composition has 1) weight ratio of component (1) to component (2) is in the range of 80:20 to 90:10, 2) intrinsic viscosity of xylene solubles (XSIV) in the range of 0.8 to 1.4 dl/g, 3) MFR (at 230° C. under a load of 2.16 kg) in the range of 5 to 15 g/10 min., 4) viscosity ratio in the range of 0.40 to 0.80 where Viscosity ⁢ ⁢ ratio = XSIV Intrinsic ⁢ ⁢ viscosity ⁢ ⁢ of ⁢ ⁢ component ⁢ ⁢ ( 1 ) .
US11339278B2 Polyethylene composition and film having high stiffness, outstanding sealability and high permeability
A polyethylene composition includes a first polyethylene which is an ethylene copolymer having a weight average molecular weight of from 70,000 to 250,000 and a molecular weight distribution Mw/Mn of <2.3, a second polyethylene which is an ethylene copolymer or homopolymer having a weight average molecular weight of from 15,000 to 100,000, a molecular weight distribution Mw/Mn of >2.3, and a third polyethylene which is an ethylene copolymer or homopolymer having a weight average molecular weight of from 70,000 to 250,000 and a molecular weight distribution Mw/Mn of >2.3, where the first polyethylene has more short chain branching than the second polyethylene or the third polyethylene. The polyethylene composition has a soluble fraction in a CEF analysis of at least 10 weight percent. Film made from the polyethylene composition may have a machine direction 1% secant modulus of 200 ≥MPa (at a film thickness of about 1 mil), a seal initiation temperature (SIT) of ≤90° C. (at a film thickness of about 2 mil), an area of hot tack window (AHTW) of ≥160 Newtons·C° (at a film thickness of about 2 mil) and an oxygen transmission rate (OTR) of ≥600 cm3 per 100 inch per day (at a film thickness of about 1 mil).
US11339277B2 Heavy duty support
A polymer composition comprising a blend of two or more high density polyethylenes: (A) a first high density polyethylene having a density of at least 940 kg/m3 and an MFR2 of 0.25 g/10 min or less; and (B) a second high density polyethylene having a density of at least 940 kg/m3 and an MFR2 of 1.0 g/10 min to 20 g/10 min; wherein said polymer composition has an MFR2 of 0.25 to 15 g/10 min and wherein the components (A) and (B) combined form at least 91 wt % of said polymer composition.
US11339276B2 Rubber composition and pneumatic tire
The present technology provides a rubber composition having: from 30 to 50 parts by mass of carbon black having a nitrogen adsorption specific surface area of from 100 to 130 m2/g, from 25 to 40 parts by mass of carbon black having a nitrogen adsorption specific surface area of from 37 to 60 m2/g, from 1.5 to 2.2 parts by mass of sulfur as a pure sulfur content, and from 110 to 200 mass % of a sulfenamide-based vulcanization accelerator relative to the pure sulfur content compounded in 100 parts by mass of diene rubber containing from 30 to 60 parts by mass of isoprene rubber and from 40 to 70 parts by mass of butadiene rubber.
US11339275B2 Compositions and methods for food packaging
Compositions comprising a fiber component, optionally a dispersing agent operable to disperse the fiber component to create a fiber matrix, a starch component distributed essentially throughout the fiber matrix, and a filler component are disclosed. Methods of forming articles such as containers and packages from such compositions are also disclosed.
US11339274B2 Resin composition and resin molded article
A resin composition includes a cellulose ester compound (A), a poly(meth)acrylate compound (B) containing 50% by weight or more of a constituting unit derived from a (meth)acrylic acid alkyl ester, a polyester resin (C), and at least one polymer (D) selected from a polymer with a core shell structure having a core layer and a shell layer containing a polymer of a (meth)acrylic acid alkyl ester on a surface of the core layer, and an olefin polymer which is a polymer of an α-olefin and a (meth)acrylic acid alkyl ester and contains 60% by weight or more of a constituting unit derived from the α-olefin.
US11339273B2 Flame retardant composition and flame-retardant thermoplastic resin composition containing said flame retardant composition
The present invention provides a non-halogen-based flame retardant composition and flame retardant resin composition wherein a small amount of addition achieves an excellent flame retardancy, an amount of elution of a flame retardant from the thermoplastic resin is extremely small even under high temperature and high humidity, and it has water-resistant property. A phosphate ester amide compound of general formula (I), a nitrogen-containing compound having a 1,3,5-triazine structure or 1,3,5-triazine fused ring structure, and optionally, a metal oxide or metal salt are used together. Further optionally, a dripping inhibitor is blended. wherein, R1, R2, R3 and R4 are each independently hydrogen or C1-3 alkyl, R11, R12, R13 and R14 are each independently C1-3 alkylene, R15 is C1-6 alkylene, and R5 and R6 are each independently hydrogen or C1-6 alkyl.
US11339271B2 Crosslinking agent, polymer composition containing crosslinking agent, and crosslinked product of same
A crosslinking agent which is based on an aluminate complex salt of a hydroxyl group-containing organic compound, which crosslinks a carboxy group and a nitrile group. When the crosslinking agent is added to a carboxy group-denatured NBR latex, gloves having flexibility and a strength comparable to those of natural rubber gloves can be manufactured. Furthermore, the excellent creep resistance is a big characteristic. Moreover, unlike normal sulfur vulcanization gloves, the gloves do not contain sulfur and a vulcanization accelerator, and do not necessarily require addition of zinc oxide.
US11339270B2 Conductive polymer
A polymer composition comprises at least one substantially non-conductive polymer binder and at least first and second electrically conductive fillers, wherein the first electrically conductive filler is comprised of particles having a void bearing structure, and the second electrically conductive filler is comprised of particles which are substantially spherical in shape.
US11339266B2 Composition, foamed silicone elastomer formed therefrom, and methods of formation
A composition for forming a foamed silicone elastomer is disclosed. The composition comprises: A) an organopolysiloxane having at least two silicon-bonded ethylenically unsaturated groups per molecule; B) an organohydrogensiloxane having at least two silicon-bonded hydrogen atoms per molecule; C) a hydrosilylation catalyst; D) a chemical blowing agent; and E) a physical blowing agent. The hydrosilylation catalyst C) is present in a catalytically effective amount. The chemical blowing agent D) has at least one hydroxyl (OH) group, and is present in an amount to provide a OH content >0 and <500 parts per million (ppm). The physical blowing agent E) undergoes a phase change from a liquid to a gaseous state during exposure to atmospheric pressure and a temperature ≥0° C. The blowing agents D) and E) are different from one another. A foamed silicone elastomer, and methods of forming the composition and foamed silicone elastomer are also disclosed.
US11339265B2 Method for making a thermoplastic foam article
A variety of foams and foam components are provided, including foam components for articles of footwear and athletic equipment. The articles include a composition having a foam structure, wherein the composition includes a thermoplastic copolyester elastomer comprising: (a) a plurality of first segments, each first segment derived from a dihydroxy-terminated polydiol; (b) a plurality of second segments, each second segment derived from a diol; and (c) a plurality of third segments, each third segment derived from an aromatic dicarboxylic acid. Methods of making the compositions and foams are provided, as well as methods of making an article of footwear including at least one of the foam components. In some aspects, the foams and foam components can be made by extrusion or injection molding to foam the polymeric composition, or extrusion or injection molding to foam the polymeric composition followed by compression molding of the foam.
US11339264B2 Functionalized particulate bicarbonate as blowing agent, foamable polymer composition containing it, and its use in manufacturing a thermoplastic foamed polymer
A chemical blowing agent for foaming a thermoplastic polymer, for example PVC plastisol or a polymer resin in an extrusion process, said chemical blowing agent comprising a functionalized particulate bicarbonate containing at least one polyoxyalkylene additive, preferably excluding an exothermic blowing agent. The polyoxyalkylene additive may be selected from the group consisting of polyoxyalkylenes, any derivative thereof, salts thereof, and any combinations thereof. The particulate bicarbonate may be preferably functionalized by spray-coating, extrusion or co-grinding with at least one polyoxyalkylene additive. The functionalized particulate bicarbonate may comprise 50 wt % to less than 100 wt % of the bicarbonate component, and 0.02-50 wt % of the additive. The functionalized particulate bicarbonate may further comprise 0.1-5 wt % silica. A foamable polymer composition comprising such chemical blowing agent. A process for manufacturing a foamed polymer, such as foamed PVC, comprising shaping and heating the foamable polymer composition, and a foamed polymer obtained by such process.
US11339263B2 Fibrillated polymer compositions and methods of their manufacture
The disclosure is directed to polymer compositions comprising a matrix polymer component comprising a crystalline or semi-crystalline polymer; and a fibrillated fluoropolymer, a fibrillated fluoropolymer encapsulated by an encapsulating polymer, or a combination thereof. Methods of preparing and using these polymer compositions, as well as articles comprising the polymer compositions, as also described.
US11339261B2 Prepreg and fiber-reinforced composite material
A prepreg contains: a reinforcing fiber material; and a resin composition with which the reinforcing fiber material is impregnated. The resin composition contains an epoxy resin, an amine curing agent, and an imidazole curing agent. An amount of the amine curing agent is less than or equal to 3.8 parts by mass, relative to 100 parts by mass of the epoxy resin, and a sum of the amount of the amine curing agent and an amount of the imidazole curing agent is less than or equal to 10 parts by mass, relative to 100 parts by mass of the epoxy resin. The fiber-reinforced composite material is a cured product of the prepreg.
US11339252B2 Polysiloxazane compound, method for producing the same, and composition containing the same and cured product thereof
A polysiloxazane compound including a repeating unit of the following general formula (1), and having a number average molecular weight of 500 to 100,000 as measured by gel permeation chromatography versus polystyrene standards, wherein R1 and R2 each independently represent a substituted or unsubstituted C1-C50 monovalent hydrocarbon group optionally containing a hetero atom, Xs each independently represent a methyl group, an oxygen atom, NH—SiX2, or (NH)(3-r)/2—SiR1R2r (R1 and R2 have the same meaning as provided above), or Xs are joined to one another to represent an oxygen atom, n is an integer of 0 to 8, when the number of NH—SiX2 is denoted by p, p satisfies 0≤p/(2n+4)≤0.5, r is an integer of 0, 1, or 2, and a and b are numbers satisfying 0
US11339250B2 Polyamide-imide film and process for preparing the same
Embodiments provide a polyamide-imide polymer film, which comprises a polyamide-imide polymer formed by polymerizing a diamine compound, a dianhydride compound, and a dicarbonyl compound; and silica particles, wherein the number of aggregates having an average diameter of 150 to 200 nm observed in a cross-section cut in the thickness direction of the polyamide-imide film is less than 0.5/μm2, and a process for preparing the same.
US11339249B2 Compound having fluorene skeleton, and method for manufacturing same
Provided are a novel compound having a fluorene skeleton, and a method for manufacturing the same, the compound having a low palladium content or other content of a specific metal or content of a specific compound in a raw material alcohol, and being excellent in hue or various characteristics (optical characteristics, heat resistance, moldability, and other characteristics) as a raw material or in a resin that uses the raw material. This compound is a mixture of compounds having a fluorene skeleton represented by formula (1) (in formula (1), the rings Z being (same or different) aromatic groups, R1 and R2 each independently representing a hydrogen atom, a halogen atom, or a C1-12 hydrocarbon group which may include an aromatic group, Ar1 and Ar2 representing C6-10 aromatic groups which may have a substituent, L1 and L2 representing alkylene groups, j and k each independently representing an integer of 0 or greater, and m and n each independently representing an integer of 0 to 5), the mixture of compounds having a fluorene skeleton being characterized in that the content of elemental palladium therein satisfies formula (2) ((2): 0≤Pd≤50 ppm), and among the mixture of compounds represented by formula (1), compounds comprising the integers m=1-5 and n=0 are included in a range of 0-5%.
US11339246B2 Preparation method of polymer
The present application can provide a preparation method that can effectively produce a polymer having desired molecular weight characteristics and solubility in a solvent, and having a monomer composition, which is designed freely and variously according to the purpose, without unnecessary components with excellent polymerization efficiency and conversion rates, and a dispersion comprising the polymer formed by the preparation method.
US11339245B2 Monomer mixture and curable composition containing same
The present invention is to provide a monomer mixture that is cured rapidly even in the presence of oxygen and that forms a cured product having high hardness and excellent adhesion to metals and/or glass. The monomer mixture according to an embodiment of the present invention contains two or more types of cationically polymerizable monomers. As the cationically polymerizable monomers, the monomer mixture contains at least 10 wt. %, based on a total amount of the monomer mixture, of a compound having at least one cationically polymerizable group selected from the group consisting of a vinyl ether group, an epoxy group, and an oxetanyl group, and at least one hydroxy group in a molecule, and at least 5 wt. %, based on the total amount of the monomer mixture, of a compound represented by Formula (b). In the formula, R represents an s-valent straight-chain or branched saturated aliphatic hydrocarbon group or an s-valent group having two or more straight-chain or branched saturated aliphatic hydrocarbon groups bonded to each other through an ether bond, and s represents an integer of 2 or greater.
US11339243B2 Epoxy resin composition, molding material for fiber-reinforced composite material, and fiber-reinforced composite material
An epoxy resin composition contains components (A)-(C), and satisfies the expressions below: Component (A): an aliphatic epoxy resin having one hydroxyl group and two to three epoxy groups in one molecule; Component (B): an aliphatic epoxy resin having no hydroxyl group and three epoxy groups in one molecule; Component (C): a polyisocyanate compound; 0.125≤A/B≤3; and 0.2<(A+B)/T≤0.8 (A: parts by mass of component (A), B: parts by mass of component (B), and T: total parts by mass of the epoxy resins in the epoxy resin composition).
US11339241B2 Water-soluble and/or water-swellable hybrid polymer
A water-soluble and/or water-swellable hybrid polymer comprising: (i) from 5 wt.-% to 95 wt.-% water-soluble and/or water-swellable polysaccharide polymer; (ii) from 5 wt.-% to 95 wt.-% synthetic polymer comprising: (a) from 90 mol-% to 99.9 mol-%, preferably 95 mol-% to 99.5 mol-% of repeating units according to Formula (1) (b) from 0.01 mol-% to 10 mol-%, preferably to 5 mol-%, more preferably to 3 mol-% of crosslinking or branching units, wherein the crosslinking or branching units result from the incorporation of a monomer comprising at least two olefinically unsaturated double bonds; wherein components (i) and (ii) are polymerized by radical precipitation polymerization in a polar solvent.
US11339239B2 Polymer composition and use for making adhesive and article containing it
Polymer composition obtained from polymerization of C5 olefin composition, use for making an adhesive, and article or composite containing it.
US11339238B2 Modified conjugated diene-based polymer and rubber composition including the same
A modified conjugated diene-based polymer, and more particularly, a modified conjugated diene-based polymer having a unimodal molecular weight distribution curve measured by gel permeation chromatography (GPC), molecular weight distribution (PDI; MWD) of less than 1.7, and a Si content of 100 ppm or more based on weight, and a rubber composition including the same.
US11339231B2 Olefin-based resin composition, manufacturing method therefor, and molded article thereof
Provided are: an olefin-based resin composition that can yield a molded article having excellent transparency in which coloration is inhibited; a method for producing the olefin-based resin composition; and a molded article of the olefin-based resin composition. The olefin-based resin composition contains, with respect to 100 parts by mass of an olefin polymer: 0.001 to 10 parts by mass of one or more compounds (A) represented by Formula (1) wherein R1 to R4 each independently represent a hydrogen atom or an alkyl group having 1 to 9 carbon atoms; R5 represents a hydrogen atom or methyl; m represents 1 or 2; and M1 represents, for example, a hydrogen atom; and 0.001 to 10 parts by mass of a fatty acid metal salt (B) represented by Formula (2) wherein R6 represents a group having 10 to 30 carbon atoms and introduced from an aliphatic organic acid; n represents 1 or 2; and M2 represents an alkali metal atom or a multivalent metal inorganic group. In the olefin-based resin composition, an aluminum content in the olefin polymer is 0.01 mol or less per 1 kg of the olefin polymer.
US11339225B2 Bispecific antigen-binding construct and preparation method and use thereof
Disclosed are a bispecific antigen-binding construct and the preparation method and use thereof, wherein the construct comprises a first antigen binding unit and a second antigen binding unit, the first antigen binding unit is a single chain variable region antibody fragment ScFV which specifically binds to the surface antigen of immune cells, and the second antigen binding unit is a Slit2D2 protein fragment which specifically binds to the surface antigen Robo1 of tumour cells. That is to say, the construct can bind to the surface antigen of immune cells and the surface Robo1 molecule of tumour cells at the same time, so that as the distance between tumour cells and immune cells get smaller, the quiescent immune cells are effectively activated, and the effect of killing and wounding tumours is produced. The construct has advantages of small molecular weight and good tissue penetrability, has significant killing and wounding effects on the tumour cells which express a large amount of Robo1, and can be used in the development of anti-tumour drugs.
US11339219B2 Checkpoint blockade and microsatellite instability
Blockade of immune checkpoints such as cytotoxic T-lymphocyte antigen-4 (CTLA-4) and programmed death-1 (PD-1) shows promise in patients with cancer. Inhibitory antibodies directed at these receptors have been shown to break immune tolerance and promote anti-tumor immunity. These agents work particularly well in patients with a certain category of tumor. Such tumors may be particularly susceptible to treatment because of the multitude of neoantigens which they produce.
US11339218B2 Human monoclonal antibodies against LAG3 and uses thereof
The present disclosure provides isolated monoclonal antibodies that specifically bind to LAG3 with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human LAG3. In certain embodiments, the antibodies bind both human and monkey LAG3 but do not bind mouse LAG3. The invention provides anti-LAG3 antibodies that can inhibit the binding of LAG3 to MHC Class II molecules and that can stimulate antigen-specific T cell responses. Nucleic acid molecules encoding the antibodies of the invention, expression vectors, host cells and methods for expressing the antibodies of the invention are also provided. Immunoconjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of the invention are also provided. This disclosure also provides methods for stimulating an immune response, as well as methods for treating cancer using an anti-LAG3 antibody of the invention.
US11339217B2 Methods and agents for the diagnosis and treatment of hepatocellular carcinoma
The present invention relates to methods of diagnosing and methods of treating hepatocellular carcinoma in a subject. The invention also relates to antagonists of PLVAP proteins, such as antibodies that specifically bind PLVAP proteins, as well as compositions and kits comprising antagonists of PLVAP proteins. The invention further relates to humanized antibodies that specifically bind PLVAP protein.
US11339213B2 Methods and compositions for treatment of cancer
The present invention relates to VEGF-binding agents, DLL4-binding agents, VEGF/DLL4 bispecific binding agents, and methods of using the agents for treating diseases such as cancer, particularly colorectal, ovarian (e.g., platinum-resistant ovarian), pancreatic, and endometrial cancers. Also provided are methods, compositions, and kits for treatment of tumors or cancer using combinations that include a VEGF/DLL4 bispecific agent and one or more chemotherapeutic agents (e.g., leucovorin, 5-fluorouracil, and irinotecan; paclitaxel; gemcitabine and ABRAXANE® (albumin-bound paclitaxel for injectable suspension); and paclitaxel and carboplatin). The present invention further provides methods of using the agents or combinations of agents to inhibit growth of a colorectal, ovarian, pancreatic, or endometrial tumor. Also described are methods of treating cancer, particularly colorectal, ovarian, pancreatic, and endometrial cancer, comprising administering a therapeutically effect amount of an agent, antibody, or therapeutic combination of the present invention to a patient having a tumor or cancer.
US11339204B2 Truncated VWF
The present invention relates to novel truncated fragments of von Willebrand factor (VWF) and the use of such fragments and nucleic acids encoding such fragments in the treatment of von Willebrand disease (VWD) and haemophilia.
US11339197B2 Modified EGF protein, production method therefor, and use thereof
A modified EGF protein, a production method therefor, and a use thereof are disclosed. The modified EGF protein allows an effective delivery of EGF into the cell and exhibits an enhanced half-life span. A method for producing the modified EGF protein includes culturing conditions where host cell growth phase and protein expression phase employ different temperature conditions. A use of the modified EGF protein is also disclosed.
US11339195B2 Griffithsin mutants
The invention provides modified griffithsin polypeptides comprising the amino acid sequence of SEQ ID NO: 1, as well as corresponding nucleic acids, vectors, cells, fusion proteins, constructs, conjugates, and methods of inhibiting viral infection.
US11339193B2 CDP protein secretion inhibitors
Provided herein are compounds that inhibit protein secretion, e.g., via inhibition of Sec61. Also provided are compositions of the inhibitor compounds, and methods of using these inhibitors. The compounds disclosed herein can be used, e.g., for the treatment of cancer, arthritis, and/or inflammation.
US11339190B2 Peptides for the treatment of covid-19
Compositions for inhibiting the binding between ACE2 and SARS-CoV-2 spike S1 are disclosed. Methods of treating COVID-19 are disclosed. Methods of making an in vivo model of COVID-19 are also disclosed.
US11339189B2 DNA primase and gyrase inhibitors
Disclosed herein are compounds that are selective DNA primase and/or gyrase inhibitors. Further disclosed are pharmaceutical compositions comprising these compounds, and the uses of these compounds for treating disorders associated with microbial infections.
US11339188B2 Compounds for the treatment of cancer
Provided herein are compounds useful for the treatment of cancer.
US11339184B2 Antibacterial compounds, compositions thereof, and methods using same
The present disclosure includes novel compounds useful as antimicrobial agents. The present disclosure further includes methods useful. The present disclosure further includes compositions and methods for treating or preventing a bacterial infection. The present disclosure further includes compositions and methods useful for preventing or reducing the growth or proliferation of microorganisms.
US11339183B2 Phosphate and phosphonate derivatives of 7-amino-5-thio-thiazolo[4,5-d]pyrimidines and their use in treating conditions associated with elevated levels of CX3CR1 and/or CX3CL1
There is provided a compound of formula I, wherein R1, R2, Q1 and are as defined herein, which compounds are useful in the treatment of diseases and disorders associated with elevated levels of CX3CR1 and/or CX3CL1, in particular acute and/or chronic inflammation, eye diseases, lung diseases, skin diseases, joint and/or bone diseases, autoimmune diseases, cardiovascular diseases, metabolic diseases, brain diseases, neurodegenerative diseases, pain, cancer, liver diseases, kidney diseases, gastrointestinal diseases, human immunodeficiency virus and mood disorders.
US11339182B2 Organic electroluminescent materials and devices
A compound of Formula (LA)n-M-(LC)m, wherein the ligand LA is of Formula I, and the ligand LC is selected from Formula I that is different than ligand LA, a monoanionic bidentate ligand, or a monoanionic monodentate ligand. M is a metal; and n is 1 or 2, and m is 0, 1 or 2. Ring A is a 5-membered or 6-membered heteroaryl ring, which is bonded to Ring B; Z is selected from O or S; Z1 is selected from a carbene C or N; and Z2 is selected from C or N. Moreover, two adjacent ring carbons of Ring B will form a group of formula D, wherein * represents the point of attachment to the two adjacent ring carbons, Formula D, wherein X is selected from NRN, O, S, or Se; and RN is selected from the group consisting of hydrogen, deuterium, alkyl, cycloalkyl, heteroalkyl, aryl, heteroaryl, and combinations thereof; and Y1, Y2, Y3, and Y4 are independently CRY1, CRY2, CRY3, and CRY4, respectively, or N, and Ring D has no more than two nitrogen ring atoms. An OLED that includes a compound of the Formula I above in an organic layer is also described.
US11339177B2 Heteroaryl compounds as inhibitors of necrosis, composition and method using the same
The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to necrosis. Formula (I) is shown below:
US11339174B2 γ-spiroketal-γ-lactones and pharmaceutical composition containing same and process for preparation thereof
The present invention relates to γ-spiroketal-γ-lactones of formula (I) or a stereoisomer, ester, hydrate, solvate or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier, diluent or excipient and a process for preparation thereof. The present invention further provides a pharmaceutical composition comprising γ-spiroketal-γ-lactones of formula (I) or a salt thereof.
US11339173B2 Benzimidazoles and methods of using same
The present disclosure is concerned with benzimidazole compounds and methods of using these compounds for the treatment of hepatitis (e.g., hepatitis C), RNA virus infections (e.g., Zika virus, dengue virus, Powassan virus, Chikungunya virus, Enterovirus, respiratory syntactical virus (RSV), Rift Valley fever, Influenza virus, Tacaribe virus, Mayaro virus, West Nile virus, yellow fever virus, and coronavirus), and disorders of uncontrolled cellular proliferation (e.g., cancer). This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US11339166B2 Compounds and pharmaceutical compositions thereof for the treatment of diseases
The present invention discloses compounds according to Formula I: wherein R1, R2, R3a, R3b, X, Y1, Y2, Y3, and Z are as defined herein. The present invention relates to compounds, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of inflammatory diseases, autoinflammatory diseases, autoimmune diseases, proliferative diseases, fibrotic diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformation, diseases involving impairment of bone turnover, diseases associated with hypersecretion of TNFα, interferons, IL-6, IL-12 and/or IL-23, respiratory diseases, endocrine and/or metabolic diseases, cardiovascular diseases, dermatological diseases, and/or abnormal angiogenesis associated diseases by administering the compound of the invention.
US11339165B2 Pyrazolopyrimidines having activity against the respiratory syncytial virus (RSV)
The invention concerns compounds having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further concerns pharmaceutical compositions comprising these compounds and the compounds for use in the treatment of respiratory syncytial virus infection. Formula (Ia).
US11339163B2 BRaf inhibitors and use thereof for treatment of cutaneous reactions
The present invention discloses novel BRaf inhibitors, compositions comprising these BRaf inhibitors and uses thereof for the treatment, amelioration and/or prevention of cutaneous reactions.
US11339161B2 Triazolo pyridines as modulators of gamma-secretase
The present invention relates to triazolo pyridines of formula (II) and their use as modulators of #-secretase. In particular, the present invention relates to compounds which interfere with #-secretase and/or its substrate and therefore modulate the formation of Aβ peptides. Accordingly these compounds can be used for the treatment of Aβ-related pathologies, e.g. Alzheimer's disease.
US11339159B2 Toll-like receptor agonists
The present invention relates to imidazo-pyridinyl compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.
US11339157B1 4H-pyrrolo[3,2-c]pyridin-4-one derivatives
Compounds of formula (I) processes for their production and their use as pharmaceuticals.
US11339153B2 Compounds useful in modulating the farnesoid X receptor and methods of making and using the same
Provided are compounds that can act as a modulator of a farnesoid X receptor (FXR) and that can be useful in the treatment of diseases and/or disorders associated with the FXR such as bile acid related disorders, metabolic syndrome, type-2-diabetes, hyperlipidemia, hypertriglyceridemia, primary biliary cirrhosis (PBC), fatty liver disease, nonalcoholic steatohepatitis (NASH), inflammatory autoimmune diseases, Crohn's disease, multiple sclerosis, atherosclerosis, kidney disorders (including chronic kidney disease), hepatic and colon cancers, and other disorders. The compounds are in the class of sulfinic acid compounds and can be an enantiomer, stereoisomer, tautomer, solvate, hydrate, prodrug, metabolite, or pharmaceutically acceptable salt thereof. Compositions including such compounds are also provided along with methods for preparing compounds of the present invention and their use.
US11339151B2 Aliphatic acid amide derivative
The present invention relates to a compound represented by formula (1): the compound having antagonist activity against serotonin 5-HT2A receptors and serotonin 5-HT7 receptors; or a pharmaceutically acceptable salt of the compound. (In the formula, Z is a nitrogen atom and the like; Y is carbonyl and the like; m and n are 1 and the like; R1a through R1d, R2a through R2d, and R4a through R4d are a hydrogen atom and the like; R3 is alkyl and the like; and Q is a specific bicyclic group.)
US11339150B2 Benzimidazole compounds as HDAC6 inhibitors
Novel compounds of Formula I are described, where the compounds are selective HDAC6 inhibitors suitable for treatment of diseases associated with HDAC6, where X, Y, Z, A1, A2, Q1 and Q2 are as described.
US11339149B2 Heterocyclic compounds as immunomodulators
Disclosed are compounds of Formula (I), methods of using the compounds as immunomodulators, and pharmaceutical compositions comprising such compounds. The compounds are useful in treating, preventing or ameliorating diseases or disorders such as cancer or infections.
US11339146B2 Compositions and methods for viral sensitization
Provided are compounds of Formula (II) that enhance the efficacy of viruses by increasing spread of the virus in cells, increasing the titer of virus in cells, or increasing the antigen expression from a virus, gene or trans-gene expression from a virus, or virus protein expression in cells. Other uses, compositions and methods of using same are also provided.
US11339140B2 Compositions and methods comprising substituted 2-aminoimidazoles
The present invention presents 2-(acylamino)imidazoles with therapeutic activity, including selective activity against cancer cells, and compositions comprising them. Methods of using and preparing the 2-(acylamino)imidazoles are also presented.
US11339139B2 Treprostinil derivative compounds and methods of using same
Compounds represented by formulae I, II, III, and IV including pro-drugs for treprostinil and prostacyclin analogs. Uses include treatment of pulmonary hypertension (PH) or pulmonary arterial hypertension (PAH). The structures of the compounds can be adapted to the particular application for a suitable treatment dosage. Transdermal applications can be used.
US11339136B2 Compounds and compositions for treating conditions associated with NLRP activity
In one aspect, compounds of Formulae (I) and (II), or pharmaceutically acceptable salts thereof, are featured; Formula (I), Formula (II) or a pharmaceutically acceptable salt thereof, wherein the variables shown in Formulae (I) and (II) can be as defined anywhere herein.
US11339135B2 Method for producing triazine compound
The present invention provides an industrially advantageous method for producing a 3,5-disubstituted triazine compound that is useful as an active pharmaceutical ingredient. More specifically, the present invention provides a production method, whereby it becomes possible to efficiently produce a 3-oxo-5-substituted triazine in water without the need to isolate an intermediate that may have mutagenicity, and it also becomes possible to perform the production without the need to isolate a product in each of multiple steps. Namely, the present invention provides a method for producing a compound represented by formula I or a salt thereof, the method including a step of reacting a compound represented by the following formula IV or a salt thereof with a base in water, and optionally including a step of forming a salt thereof. Specifically, the present invention provides a method for producing a compound represented by formula I or a salt thereof, the method including a step of derivatizing a compound represented by formula II or a salt thereof into a corresponding compound represented by formula III, a salt thereof, or a derivative thereof, then a step of reacting the resulting compound, a salt thereof, or a derivative thereof with aminourea or a salt thereof in water to produce a compound represented by formula IV or a salt thereof, and then a step of reacting the resulting compound or a salt thereof in the presence of a base. (wherein ring A represents an optionally substituted aryl group or an optionally substituted heteroaryl group)
US11339131B2 Process for preparing elagolix sodium and intermediates thereof
The present invention provides improved processes for the preparation of elagolix and intermediates thereof. The intermediate of formula VII is achieved by a coupling reaction of a compound of formula V and a N-benzylidene protected compound of formula IV: The present invention is suitable for a large-scale production, avoiding the use of potential genotoxic substances and can be performed under mild conditions.
US11339127B2 Salt forms of URAT-1 inhibitors
Provided herein are compounds, salts, crystalline forms, and pharmaceutical compositions that are related to thiobutyrate compounds, such as Compound (1) and its salts (such as sodium, potassium, and calcium salt), as well as methods of preparing the same. Also provided herein are methods of using the compounds, salts, crystalline forms, and pharmaceutical compositions for the treatment of diseases or disorders, such as gout and hyperuricemia.
US11339123B2 Alkoxylated secondary alcohol sulfates
The invention relates to the compounds of formula (I), in which R1 and R2 represent a linear, branched or cyclic, saturated or unsaturated hydrocarbon group, comprising 1 to 6 carbon atoms, wherein the sum of the carbon atoms of the groups R1 and R2 is from 2 to 7; A represents a chain of one or a plurality of units of ethylene oxide, propylene oxide, butylene oxide and mixtures thereof; and n is an integer between 1 and 100 inclusive. The invention also relates to mineral or organic salts thereof; the use of the compounds of formula (I) and/or of one of the salts thereof as a surfactant, a wetting agent, a detergent, an emulsifying agent, a dispersant, a corrosion inhibitor, and the like; and to compositions comprising at least one compound of formula (I) and/or of one of the salts thereof.
US11339112B2 Compositions and methods comprising resveratrol
The present technology relates to synthesis of resveratrol compositions, in particular to methods of synthesizing resveratrol salicylates such as those formed through the activation of resveratrol and salicylic acid, and cosmetic and pharmaceutical compositions comprising the same.
US11339109B2 Electrochemical reduction of carbon dioxide to upgrade hydrocarbon feedstocks
A system and method with a solid oxide electrolysis cell (SOEC), including feeding carbon dioxide and an olefin to the SOEC and discharging carbon monoxide and an olefin oxide from the SOEC, wherein the olefin oxide corresponds to the olefin.
US11339107B2 Efficient distillation of ethanol
Systems and methods in accordance with the present invention provide for the efficient distillation of ethanol in an ethanol plant including a beer column. Heat is captured in the distillation process and utilized to drive operations in the ethanol plant.
US11339101B2 Cultivating material composition
Provided is a cultivating material composition including a cultivating substrate and a bio-cellulose film, wherein the bio-cellulose film is in contact with the cultivating substrate, such that highly increased yield and quality of crops, a shorter harvest period, less water and nutrient sources, and low cost can be achieved.
US11339098B2 Preparation method of nanometric size metal oxide additives that reduce the temperature of sinterized and/or increase productivity in the manufacture of ceramic parts, improving mechanical properties without affecting the gresification properties of ceramic bodies, tiles or coatings
The object of this invention is a process for manufacturing, conditioning and stabilization of a family of base additives sodium, potassium, boron, silicon, zinc, calcium oxides, among others, prepared by physicochemical and chemical synthesis methods that form nanometric structures, reformulated with deflocculant, sequestrants and dispersants additives that allow to obtain a dispersion or powder capable to decrease the sintering temperature of a ceramic body due to the high fluxing power, which is maximized by the use of nanotechnology in the structures obtained. The process consists in the preparation of nucleation seeds of metal, silicates and carbonates oxides by means of a physicochemical process, and which allow nanometric structures to grow by means of a chemical process in a chemical synthesis process wet basis of sodium, boron, silicon, zinc, potassium and calcium oxides. The combination of these oxides allows structuring elements of high fluxing power due to their high surface area and physicochemical composition. The additives prepared in this invention are chemically stabilized with deflocculating agents, which allow the additives to be incorporated into the aqueous medium grinding process of the ceramic body. Applications made with the additives of this invention allow the sintering temperature of a red body to be reduced from 1150° C. to 1000° C. and in porcelain bodies from 1180° C. to 1050° C., with the use of 0.2 to 5% of the additive, or increasing the speed of the heat treatment by up to 20%, and it can be used in the manufacture of bathroom fittings, molding parts, components for tooling, coatings, valances, enamels, vitrified pastes and other ceramic components. The present invention proposes several nanostructured additive formulations with high performance fluxing properties, which allow to optimize and standardize the sintering process and to improve the mechanical properties of the ceramic body. It also proposes different methods of application of the additive in ceramic formulations.
US11339096B1 Tungsten carbide powder
A tungsten carbide powder 1 includes bonded bodies 10 each including a plurality of tungsten carbide crystal grains 11, in which the bonded bodies 10 include, at a grain boundary 11a between the plurality of tungsten carbide crystal grains 11, a chromium-concentrated region 12 which has a chromium concentration higher than that in the tungsten carbide crystal grains 11.
US11339095B2 Sol containing nano zirconia particles for use in additive manufacturing processes for the production of 3-dimensional articles
The invention relates to the use of a printing sol as construction material in an additive manufacturing process for producing a 3-dim article, the printing sol comprising solvent(s), nano-sized crystalline zirconia particles in an amount from 2 to 25 vol.-% with respect to the volume of the sol, the average primary particle size of the nano-sized crystalline zirconia particles being in a range up to 50 nm, a first monomer being a polymerizable surface modification agent represented by formula A-B, with A being capable of attaching to the surface of the nano-sized crystalline zirconia particles and B being a radiation curable group, optionally a second monomer, the second monomer comprising at least one radiation curable moiety but no acidic or silane group(s), photo initiator(s). The invention also relates to a ceramic article obtainable according to such a process.
US11339083B2 Low dielectric glass composition, fibers, and article
Glass compositions and glass fibers having low dielectric constants and low dissipation factors that may be suitable for use in electronic applications and articles are disclosed. The glass fibers and compositions of the present invention may include between 48.0 to 57.0 weight percent SiO2; between 15.0 and 26.0 weight percent B2O3; between 12.0 and 18.0 weight percent Al2O3; between 3.0 and 8.0 weight percent P2O5; between 0.25 and 7.00 weight percent CaO; 5.0 or less weight percent MgO; and 6.0 or less weight percent TiO2. Further, the glass composition has a glass viscosity of 1000 poise at a temperature greater than 1350 degrees Celsius and a liquidus temperature greater than 1100 degrees Celsius.
US11339082B2 Glass with preferably increased storable tensile stress, chemically toughened glass article with preferably increased storable tensile stress, method for producing such glass, and use thereof
Chemically toughened glass is provided that has a depth of compressive stress for potassium of at least 4 μm and at most 8 μm; a compressive stress at a depth of 30 μm due to sodium exchange of at most 200 MPa and a minimum amount of at least 90 MPa where the thickness is 0.5 mm, at least 100 MPa where the thickness is 0.55 mm, at least 110 MPa in where the thickness is 0.6 mm, at least 120 MPa where the thickness is 0.7 mm, and at least 140 MPa where the thickness is 1 mm; a ratio of sodium exchange depth, in μm, to the thickness, in mm, that is greater than 0.130; and a normalized integral of tensile stress that is a storable tensile stress of at least 20.6 MPa and at most 30 MPa.
US11339077B2 Fining glass using high temperature and low pressure
A glass fining system, glass fining device, and method are disclosed. The glass fining device in accordance with one aspect of the disclosure includes at least one heated orifice through which molten glass flows from a glass melter to produce at least one superheated glass stream; and a low-pressure chamber disposed downstream from the heated orifice, where the at least one superheated glass stream flows from the at least one heated orifice and into the low-pressure chamber, and where the low-pressure chamber surrounds the at least one superheated glass stream. In some embodiments, the low-pressure chamber may include at least one surface extender.
US11339067B2 Controlled simultaneous nitrification and denitrification in wastewater treatment
A process for controlling the aeration rate during the aerobic phase of a wastewater treatment process is disclosed, which comprises: (a) measuring at moment t1 the ammonium concentration [NH4+]1 and nitrogen oxide concentration [NOx]1 in a mixture of wastewater and microbial sludge; (b) determining a nitrogen oxide target concentration [NOx]F1 at the end of the aerobic phase based on at least the current ammonium concentration [NH4+]1 and the current NOx concentration [NOx]1; (c) determining a setpoint [NOx]SP1 based on interpolation between [NOx]1 and [NOx]F1; (d) adjusting the aeration rate to minimise error between [NOx]1 and [NOx]SP1; and (e) repeating steps (a) to (d) at further moments t1. The invention further concerns a process for the treatment of wastewater, using the process.
US11339063B2 Fluid circuit with integrated electrostatic discharge mitigation
A fluid circuit includes a plurality of tubing segments and a plurality of operative components. Each tubing segment includes i) a non-conductive polymer portion defining a fluid passageway and ii) one or more interior conductive fluoropolymer stripes extending axially to the ends of each of the respective tubing segments. Each operative component includes a conductive fluoropolymer that extends between a plurality of tubing connector fittings forming a part of the fluid circuit, wherein each of the tubing connector fittings conductively connect the respective conductor of the operative component to the interior conductive fluoropolymer stripes of the tubing segment to provide a path to ground that extends through each operative component and each tubing segment.
US11339059B2 Fluid injection filtration system
A method of filtering fluid for injection into an injection well comprises detecting a fluid pressure in a conduit upstream of an actuator valve, verifying that the fluid pressure is within an operating pressure range, opening an actuator valve based on the verifying, receiving a fluid having suspended solids within a filter assembly in response to opening the actuator valve, actuating a pump in fluid communication with the filter assembly based on receiving the fluid within the filter assembly, and separating at least a portion of the suspended solids in the fluid within the filter assembly.
US11339058B2 Manufacturing of perovskite films
The present disclosure relates to a mixture that includes a perovskite precursor, a solvent, and an additive that includes at least one of a first amine, a ketone, an aldehyde, a non-nucleophilic sterically hindered base, and/or a halogen-containing compound, where, upon removal of the solvent and the additive, the perovskite precursor is capable of being transformed into a perovskite.
US11339057B2 Preparation of sinterable complex oxide powder and manufacturing of transparent ceramics
To a co-precipitating aqueous solution, aqueous solutions containing (a) Tb ions, (b) at least one other rare earth ions selected from the group consisting of Y ions and lanthanoid rare earth ions (excluding Tb ions), (c) Al ions and (d) Sc ions are added; the resulting solution is stirred at a liquid temperature of 50° C. or less to induce a co-precipitate of the components (a), (b), (c) and (d); the co-precipitate is filtered, heated and dehydrated; and the co-precipitate is fired thereafter at from 1,000° C. to 1,300° C., thereby forming a sinterable garnet-type complex oxide powder.
US11339055B2 Graphite/graphene composite material, heat collector, a heat conductor, a heat dissipator, a heat-dissipation system, and a method of producing the graphite/graphene composite material
The present invention provides a graphite/graphene composite material comprising flat graphite particles and graphene aggregates, wherein the flat graphite particles are stacked using the graphene aggregates as a binder so that the basal surfaces of the graphite particles are overlapped with one another, and the graphene aggregates are composed of deposited single-layer or multi-layer graphenes.
US11339054B2 Continuous process and apparatus for producing graphene
Provided is a method of producing isolated graphene sheets, comprising: (a) providing a reacting slurry containing a mixture of particles of a graphite or carbon material and an intercalant and/or an oxidizing agent; (b) providing one or a plurality of flow channels to accommodate the reacting slurry, wherein at least one of the flow channels has an internal wall surface and a volume and an internal wall-to-volume ratio of from 10 to 4,000; (c) moving the reacting slurry continuously or intermittently through at least one or a plurality of flow channels, enabling reactions between the graphite or carbon particles and the intercalant and/or oxidant to occur substantially inside the flow channels to form a graphite intercalation compound (GIC) or oxidized graphite (e.g. graphite oxide) or oxidized carbon material as a precursor material; and (d) converting the precursor material to isolated graphene sheets.
US11339051B2 Ozone generating device, air conditioning device, and vehicle
An ozone generating device including an excimer lamp having an arc tube containing a luminescent gas, a first electrode, and a second electrode. The arc tube has a first end portion and a second end portion, a first diameter-reduced portion provided continuously from the first end portion, a diameter of which decreases as a distance from the first end portion increases, and a second diameter-reduced portion provided continuously from the second end portion, a diameter of which decreases as a distance from the second end portion increases, the first electrode is provided for an outer periphery surface of the first end portion, the second electrode is provided for an outer periphery surface of the second end portion, the arc tube is fixed via the cylindrical portion, and the first electrode is not provided over the first diameter-reduced portion, and/or the second electrode is not provided over the second diameter-reduced portion.
US11339050B2 Actuator device
An actuator device includes a support portion, a movable portion, a connection portion which connects the movable portion to the support portion on a second axis, a first wiring which is provided on the connection portion, a second wiring which is provided on the support portion, and an insulation layer which includes a first opening exposing a surface opposite to the support portion in a first connection part located on the support portion in one of the first wiring and the second wiring and covers a corner of the first connection part. The rigidity of a first metal material forming the first wiring is higher than the rigidity of a second metal material forming the second wiring. The other wiring of the first wiring and the second wiring is connected to the surface of the first connection part in the first opening.
US11339047B2 Dispense control system for a refrigerator appliance
A dispense control system for filling a container using a dispensing assembly of a refrigerator appliance and a method for operating the same are provided. The dispense control system includes an emitter for generating a beam of energy and a scanning assembly for selectively directing the beam of energy along a scan path comprising a plurality of scan positions. A receiver detects the beam of energy reflected by the container or the liquid at each of the plurality of scan positions and a controller determines a height of the container or the liquid at each of the plurality of scan positions along the scan path based at least in part on a travel time of the beam of energy between the emitter and the receiver.
US11339045B2 Flavor and additive delivery systems and methods for beverage dispensers
Flavor and additive delivery systems and methods for beverage dispensers are disclosed. An example manifold of a beverage dispenser includes a base defining a base cavity and configured to extend through an opening defined by an outer wall. The manifold includes a first housing coupled to the base and defining a housing cavity. The base cavity and the housing cavity are adjacent to each other to form a chamber. The manifold includes a body coupled to the first housing and defining a body cavity and angled apertures. The manifold includes an insert housing that is coupled to the body and extends at least partially through the body cavity. The manifold includes an insert housed within the insert housing and defining a water outlet for spraying water downward into the chamber. The angled apertures are configured to receive nozzles that extend at least partially into the chamber at the predefined angle.
US11339042B2 Mobile elevating work platform/stock picker
A mobile elevating work platform includes a chassis and fixed wheels, caster wheels, and a driving and steering wheel secured to the chassis. A control implement coupled with the driving and steering wheel is configured to adjust a steering position of the driving and steering wheel. A drive motor is operable to drive the driving and steering wheel. A platform may be raisable and lowerable with a mast assembly. The control implement may be adjustable to accommodate operator physical characteristics.
US11339041B2 Power lift
Power machines and control systems used thereon include a lift cylinder, a tilt cylinder, and a slave cylinder mechanically connected to assist the lift cylinder with raising a boom. With a lift control valve controlled to cause extension of the lift cylinder to raise the boom, pressure from a hydraulic source is provided to the slave cylinder to aid in raising the boom. Resulting increased pressure on a side of the slave cylinder opens load holding valves, allowing hydraulic pressure from the tilt cylinder to be communicated to the slave cylinder such that tilt cylinder pressure due to a heavy load on an implement aids in raising the boom.
US11339040B2 Handle head for an electric transport vehicle
A handle head of an electric transport vehicle includes a first body and a second body, with the second body being releasably connected to the first body. The second body conveniently may be disassembled from the first body when the vehicle is going to be shipped, and then reassembled for use of the vehicle. Disassembly of the second body from the first reduces the length of the handle and the volume of the handle head that otherwise need to be accommodated during shipping.
US11339038B2 System for controlling the operation of a hydraulic winch
A system for controlling a winch assembly having a hydraulic motor, a drum, a cable, and a cable tension sensor. A controller is configured to access a winch load threshold defining a hold zone and a reel zone, and one of the hold zone and the reel zone including loads greater than the winch load threshold and another of the hold zone and the reel zone including loads less than the winch load threshold. The controller is further configured to determine whether the winch assembly is operating within the hold zone or the reel zone, and generate a zero flow command while the winch assembly is operating within the hold zone to prevent rotation of the hydraulic winch motor, and generate a pressure differential command while the rotatable winch drum is operating within the reel zone to permit rotation of the hydraulic winch motor.
US11339036B2 Control stand for a crane, excavator, and the like
A control stand is disclosed for controlling a crane, an excavator, a crawler, or a similar construction machine having a seat, control elements actuable from the seat for inputting control commands, a display apparatus for displaying information, and a control unit for generating adjustment signals in dependence on input control commands and/or for providing information to the display apparatus. A crane is disclosed having such a control stand that can be configured in the form of a crane operator's cabin. The control elements and/or the display apparatus of the control stand and various further auxiliary units can be individually configurable. Personal pre-settings can be saved and can be reinvoked when the control stand or the crane is to be controlled by a certain machine operator.
US11339035B2 Controlling of lifting device
A method and equipment for controlling a lifting device, wherein a main steering direction of the control device used by an operator is selected from at least two options; the impact of the control device on the directions of motion of the lifting device is changed according to the selected main steering direction; and the lifting device is controlled with a control device.
US11339027B2 Lift car for a lift installation and method for opening and closing a door opening
An elevator car for an elevator installation may include at least one side wall having a doorway and an elevator car door. For opening and/or closing the doorway, the elevator car door can be moved at least partially parallel to the side wall on an outside of the side wall. In opening and/or closing, the elevator car door can be moved at least partially in a direction perpendicular to the side wall. In the closing process, the elevator car door can be at least partially sunk in the doorway. A coupling element may couple the elevator car door to a shaft door in at least one of opening or closing the elevator car door.
US11339026B2 System for processing pressure sensor data
A method of detecting maintenance requirements of a system for conveying a car through a passageway is provided. The method comprising: detecting pressure data for at least one or more locations along a passageway using a pressure sensor; comparing the pressure data to benchmark pressure data for each of the one or more locations; determining a pressure data variance at a first location of the one or more locations in response to the pressure data and the benchmark pressure data; and identifying an identity of a car stop location door system located at the first location when the pressure data variance is greater than a selected tolerance.
US11339022B2 Sheet stacker and image forming apparatus incorporating the sheet stacker
A sheet stacker includes a sheet stacking member, a biasing force applier, an angle changer, and a biasing force change reducer. The sheet stacking member has an upstream portion in a sheet conveyance direction. The upstream portion is movable in a vertical direction. The biasing force applier is configured to bias the sheet stacking member upward. The angle changer is configured to change an angle of a sheet stacking face of the sheet stacking member, relative to a surface of a sheet conveyed through a sheet conveying portion. The biasing force change reducer is configured to restrain a change of a biasing force acting on the sheet stacking member, before and after a change of the angle of the sheet stacking member by the angle changer.
US11339021B2 Device for winding and changing the reels of web material as well as a dedicated process
A device for winding and changing reels of web material includes two independently operable central drives for shifting winding shafts, a drivable winding shaft guide, a contact roller unit and slitting units. Both right-hand winding and left-hand winding are realized, whereby the device is without a prewinding station. For a winding shaft change, the drivable winding shaft guide is driven from the winding position into the parking position and is disconnected. Subsequently, the second central drive is connected to the winding shaft guide and is driven from its parking position into the winding position where the second central drive is connected with a new winding shaft. The contact roller unit is driven against the winding shaft and the web material is cut through by a slitting device and then wound to a new reel.
US11339020B2 Paper stacking apparatus, control method, and recording medium
A paper stacking apparatus according to an embodiment of the present disclosure includes a stacking table, a first sensor, and a hardware processor. The stacking table includes an upper face on which papers are stacked, the stacking table being capable of being elevated and lowered by a drive mechanism. The first sensor is disposed at a first position and configured to detect the upper face of the stacking table or an upper face of stacked objects stacked on the stacking table. The hardware processor is coupled to the drive mechanism and the first sensor. The hardware processor is configured to determine that the stacking table is excessively elevated when an elapsed time after starting to detect the object by the first sensor is at least a first excessive-elevation determination value of time.
US11339018B2 Medium conveying apparatus for controlling feeding a medium
A medium conveying apparatus includes a feed roller, a brake roller, a motor to generate a driving force, a first transmission mechanism to transmit the driving force to the brake roller through a first torque limiter, to rotate the brake roller in a direction opposite to a medium feeding direction, a second transmission mechanism to transmit the driving force to the brake roller through a second torque limiter, bypassing the first torque limiter, to rotate the brake roller in the direction opposite to the medium feeding direction, and a processor to detect media multi-feed, and perform control in such a way as to transmit the driving force to the brake roller by the second transmission mechanism and also cause the feed roller to be driven to rotate in the direction opposite to the medium feeding direction by the brake roller, when the media multi-feed is detected.
US11339017B2 Recording-material-transporting device and image forming apparatus
A recording-material-transporting device includes an attracting part to which a recording material is attracted from below, and a blowing device that blows air from a position higher than the attracting part to an edge of the recording material attracted to the attracting part.
US11339015B2 Sheet feeding apparatus and image forming apparatus
A sheet feeding apparatus includes a storage portion, a sheet supporting portion, a feed portion, a drive portion to output driving force that lifts the sheet supporting portion, and a rotation shaft rotatably supported by the storage portion and including an engaging portion disposed on one end side in an axial direction of the rotation shaft. The engaging portion engages with the drive portion, and a pressing portion is fixed to the rotation shaft and presses the sheet supporting portion from below when the rotation shaft is rotated by the drive portion. A rotary damper joins with the rotation shaft on another end side of the rotation shaft and reduces rotary motion of the rotation shaft. The pressing portion is disposed between the engaging portion and the rotary damper in the axial direction.
US11339014B2 Attachment, feed device, and image forming apparatus
An attachment is attachable to and detachable from a sheet stacking board. The attachment includes an end fence configured to restrict a position of a trailing end of a sheet in a conveying direction. The end fence includes a facing surface facing the trailing end of the sheet. The facing surface includes an inclined surface inclined with respect to a vertical direction of a stacking surface on which the sheet is stacked, such that a higher part of the facing surface is located more upstream in the sheet conveying direction.
US11339009B2 System for performing a processing step on device parts of simulated smoking devices, such as electronic cigarettes
A system for performing a processing step on device parts of simulated smoking devices, such as electronic cigarettes, system comprising a processing station to perform the processing step on the device parts, product carriers to hold the device parts during the processing step, a first transport device and a second transport device to move the product carriers along at least part of a processing trajectory extending through the processing station.
US11339008B2 Transport system, transport controller, and transport vehicle control method
A transport system includes a transport vehicle that transports an article, and a transport controller that controls the transport vehicle based on a host transport instruction received from a host controller. The transport controller includes a transport instructor which, in accordance with a host transport instruction, provides the transport vehicle with a transport instruction to transport an article at a pickup point to an unloading point, an overwriting processor which, in accordance with a host cancellation instruction to cancel the host transport instruction received from the host controller, overwrites the transport instruction provided to the transport vehicle with a move instruction which instructs to travel to a predetermined position and not to unload at the predetermined position, and provides the overwritten instruction to the transport vehicle, and a completion reporter which, upon the overwriting processor completing the overwriting, transmits to the host controller a cancellation completion report indicating the completion of the host cancellation instruction.
US11339003B2 Transfer apparatus and transfer method
Apparatus and method for transferring an object are disclosed. The apparatus includes a transfer track comprising a plurality of conveyors for transferring an object, an upper scheduler creating a transfer path for transferring the object and creating transfer information for controlling operations of conveyors constituting the transfer path, and a plurality of lower schedulers each receiving the transfer information from the upper scheduler and each controlling the operations of the conveyors based on the transfer information.
US11339001B2 Combination weighing apparatus
A combination weighing apparatus includes a retaining hopper that retains an article and supplies the retained article onto a transport path. The retaining hopper has a coupling portion adapted to be inserted in along the support rails and pulled off from support rails disposed in a pair. The retaining hopper is thus supportable by the support rails and is readily mounted to and dismounted from the apparatus without using any tool for cleaning and other purposes.
US11338996B2 Rack apparatus, two-wheel drive carriage and automated storage and distribution system
This invention provides a rack apparatus, a delivery carriage and the automated storage and distribution system thereof. In the rack apparatus, there are only two racks at both sides of the rack apparatus extending in a generally vertical direction. And in the carriage, there are only two driving wheels. Therefore, both the rack apparatus and the carriage simplify the structure of the rack apparatus and the carriage and reduce the installation accuracy and the failure points thereof, but still provide new improvements to keep the carriage body horizontal with the ground.
US11338994B2 Induction actuation trash container with actuation arm
An induction actuation trash container with actuation arm includes an upper container body, a pressing ring and a lower container body. The upper container body includes a cover panel, a main housing body, a body seat, an actuation arm, a rotating shaft, and an induction actuated arrangement. The main housing body has an indented cavity formed at a rear side of an inner side of the main housing body, wherein the rotating shaft is mounted across the indented cavity and penetrates through a left sidewall and an opposing right sidewall thereof. One end of the rotating arm is coupled to the rotating shaft while the other end of the rotating arm is fixedly screwed to the cover panel. The induction actuated arrangement is disposed in an interior space defined between the main housing body and the body seat when the main housing body is engaged with the body seat, wherein an actuation output of the induction actuated arrangement is operatively coupled with one end portion of the rotating shaft for generating a rotational force to drive the rotating shaft to rotate and pivotally move the actuation arm.
US11338992B2 Packaging having means for passive flight
A packaging having at least one accommodating space configured for an object to be inserted therein is provided. The at least one accommodating space is openable via a hinge. The at least one rotor blade extends from the at least one accommodating space and causes an autorotation motion of the packaging during free fall.
US11338989B2 Dispensing container
A novel chewing gum box includes a gum storage chamber, a storage chamber cover, a funnel apparatus, a gum introducing plate, a gum carrying groove, a carrying groove baffle, a push handle, a spring baffle, guide rails, guide rail grooves, a spring groove, and a spring. The gum storage chamber is communicated with the gum carrying groove through the funnel apparatus. The gum carrying groove is connected to the push handle and is capable of reciprocating along the guide rails and the guide rail groove. When retrieving gum, the box body is tilted and shaken first to allow gum in the storage chamber to slide along the gum introducing plate into the gum carrying groove via the funnel apparatus. The push handle then is actuated to have the gum pushed out along the guide rail and the guide rail groove, so that the gum is available for retrieval.
US11338987B2 Fluid vessel with configurable shape
A configurable fluid vessel including a flexible bladder having a fluid port through which a fluid such as water can be provided into the bladder. The fluid vessel includes an internal support frame within the flexible bladder to increase rigidity and can be manipulated into a predetermined shape. The fluid vessel is collapsible for storage whilst retaining rigidity when in use. The fluid vessel is particularly suited for use in explosive jet disruptors for tailoring the formation of a fluid jet.
US11338986B2 Double-walled beverage container and method of forming the same
Provided are ceramic compositions and containers, in each case comprising a ceramic (e.g., porcelain, stoneware, porcelain, or ceramic composition having properties of both) composition to which an amount of alumina has been added to provide a ceramic composition comprising 20% to 25% (wt./wt.) alumina, preferably about 22% (wt./wt.) alumina, providing a stronger material, such that wall thicknesses (e.g., of double-walled beverage containers) can be reduced or minimized to create a lighter double-walled ceramic container. The disclosed containers have a chemical and porous structure suitable for a wide array of stoneware glazes, and display water absorption rate properties comparable to stoneware. Methods of making same are provided.
US11338971B1 Smart device bottle cap
A drinkware contains a drinking bottle cap and a container. The drinking bottle cap that contains a support structure configured to support and host one or more smart devices is disclosed. The drinking bottle cap creates a secured stand for smart phones and smart tablets, such that the smart devices coupled with the drinking bottle cap are immobilized by and supported by the supporting structure of the cap. The drinkware can contain electronic components and used as a media content player similar to a music or video player.
US11338965B2 Or relating to lid arrangements
A lid arrangement (20) comprises first and second lids (22) for use in a container (12) comprising a wall arrangement (16). Each lid (22) is movable between open and closed positions. Each lid (22) comprises opposite first and second edges (124, 126), and a plurality of rib formations (132) extending transverse to the aforesaid edges (124, 126). When the first and second lids (22) are In the closed positions, the rib formations (132) of the first lid (22) overlap the rib formations (132) of the second lid (22), so that each rib formation (132) of the first lid (22) extends parallel to, and alongside, a corresponding rib formation (132) of the second lid (22) to provide a line of support (S) that extends across the lid arrangement (20) from the first edge (124) of the first lid (22) to the first edge (124) of the second lid (22).
US11338963B2 Tethered container closure
A closure for closing an opening defined by a finish of a container. The closure includes a main body and a tamper band. The tamper band is connected to the main body by a plurality of bridges. A hinge of the closure is configured to permit the main body to pivot relative to the tamper band.
US11338960B2 Container system
Engineered handheld bin system constructed of modular components creating custom heights and increased interior volume greater than known handheld plastic containers. The bin includes a base, a frame, four corner members and a wall member having a plurality of side panels. In one embodiment, the four corner members interlockably couple the frame and the base. In one embodiment, the base includes a base frame defining a channel to selectively couple to the bottom edge of the wall member and the frame defines a wall member accepting slot to engage and compress a portion of the top edge of the wall member.
US11338957B2 Packaging system including a multi-component base structure
A pallet base structure including a center deck defining a support surface extending between opposed sides and having at least two lugs extending from each of the opposed sides. A pair of base side members are positioned along respective sides of the center deck. Each base side member has first and second spaced apart base legs and a support member extending between the base legs with at least two corresponding lug receiving slots defined in the support member. The respective lugs are received in the respective lug receiving slots such that the center deck support surface is aligned with an upper surface of each support member to define a planar pallet surface. A packaging system incorporating the pallet base structure is also described.
US11338956B2 Retention packaging assembly
A retention packaging assembly (100, 200, 300, 400) includes a frame (100) and sheet assemblies (200, 300). The frame includes a central panel (102), end panels (104), and two sets of wing panels (108, 110). Each set of wing panels includes wing panels foldably coupled to the central panel and to one of the two end panels. The sheet assemblies include a sheet (208) that is attached at its ends to slot panels (204, 206, 304, 306). The slot panels of each of the sheet assemblies are selectively couplable to one of the set of wing panels. After an object is placed on a front of the central panel, the sheets of the sheet assemblies are located over the sides of the object. The sets of wing panels can then be folded to a back of the frame to cause the sheets to retain the sides of the object to the central panel.
US11338955B2 Container
A container for storing a liquid or a solid may include a container body having a container side wall and a container bottom and a container lid having a pop top arm to pivot and cooperate with a weakened area to provide access to the interior of the container body. The container body may be formed from plastic and the container lid is formed from metal, and the container body may include a vertical neck. The container body may include a lip, and the bottom wall may include a center protrusion. The bottom wall may include a depression, and the bottom wall may include a radial extending depression.
US11338953B2 Hot fill container with corner support column
The present application provides a container for a beverage filled in a hot fill process. The container may include a finish, a body section, and a base. The body section may include a number of support columns and a number of body panels. Each of the support columns may include a first raised mid-section extending into a first body panel and a second raised mid-section extending into a second body panel.
US11338949B2 Sheet storing apparatus
A sheet storing apparatus, includes: an inlet section configured to take in sheets from outside of the apparatus into the apparatus; a storing unit configured to mount a storage bag in a storing area of the storage unit; and a recognition unit configured to count the number of sheets to be stored in the storage bag mounted in the storing area of the storing unit, in which the storing unit includes: a holding section configured to hold the storage bag mounted in the storing area of the storing unit; a support section configured to support the sheets stored in the storage bag from below via the storage bag; a drive section configured to move up and down the support section between an initial position and a final position; and a control section configured to control the drive section, based on the number of sheets counted by the recognition unit.
US11338947B2 Process of packaging and modular packaging facility for packaging products on supports
A modular packaging facility has independent packaging units configured to receive one or more product loaded supports. The upper tool and the lower tool of each unit are relatively movable the one with respect to the other between at least a first position, allowing placement of the supports in the respective seats of the lower tool, and a second position, allowing coupling of a film portion of said film to said one or more product loaded supports received by the lower tool. Each unit has a vacuum arrangement and/or a controlled atmosphere arrangement and is configured to execute a packaging cycle wherein gas is removed and/or injected via holes in the supports and/or via nozzles placed between the support and the respective film portion. The process and the infrastructure may be used to contemporaneously process and pack supports of different types.
US11338944B2 Control system for executing a safing mode sequence in a spacecraft
A control system configured to execute a safing mode sequence for a spacecraft is disclosed. The control system includes one or more star trackers that each include a field of view to capture light from a plurality of space objects surrounding the celestial body. The control system also includes one or more actuators, one or more processors in electronic communication with the one or more actuators, and a memory coupled to the one or more processors. The memory stores data into a database and program code that, when executed by the one or more processors, causes the control system to determine a current attitude of the spacecraft, and re-orient the spacecraft from a current attitude into a momentum neutral attitude.
US11338943B2 Concurrent rocket engine pre-conditioning and tank loading
Concurrent rocket engine pre-conditioning and tank filling is disclosed. A disclosed example apparatus includes an inlet valve to supply a rocket propellant tank that is associated with a rocket engine with rocket propellant, and a flow director to direct at least a portion of a flow of the rocket propellant from the inlet valve to a chill line of the rocket engine to thermally condition the rocket engine as the rocket propellant tank is being filled with the rocket propellant.
US11338942B2 Spacecraft and control method
A spacecraft is provided, which includes one or more of a centrally-oriented core, which includes a computing device. The computing device includes a processor and a memory, coupled to the processor, including computer instructions to control the spacecraft. The spacecraft may also include a power source, coupled to the core, a plurality of struts, each including a root end coupled the core and a distal end, the plurality of struts extending radially from the core. The spacecraft may also include a plurality of blade deployers, coupled to distal ends of the plurality of struts and a plurality of blades, coupled to the plurality of blade deployers and extending radially away from the core and in a common plane with the plurality of struts. The plurality of blades includes material configured to be deflected by solar pressure. Each of the struts is configured to provide damping to a corresponding blade.
US11338941B2 Modular environmental control chamber
An example modular environmental control chamber (MECC) includes an outer chamber formed by an outer chamber housing section enclosing an outer face of a section of fuselage and an inner chamber formed by an inner chamber housing section enclosing an inner face of the section of fuselage. An outer chamber airflow delivery and return system includes an outer chamber blower for directing temperature-controlled air to the outer chamber through an air inflow aperture of the outer chamber housing section and an outer chamber air return duct connected to an air outflow aperture of the outer chamber housing section. An inner chamber airflow delivery and return system includes an inner chamber blower for directing humidity-controlled air to the inner chamber through an air inflow aperture of the inner chamber housing section and an inner chamber air return duct connected to an air outflow aperture of the inner chamber housing section.
US11338940B2 Predictive part maintenance
The present disclosure provides for predictive part maintenance by generating a reliability curve for an aircraft based on historic removals; setting a removal threshold on the reliability curve; tracking an installation of a given instance of the aircraft part into a given aircraft; tracking a number of cycles of the given instance of the aircraft part based on operations of the given aircraft in which the given instance of the aircraft part is installed; and in response to the number of cycles of the given instance of the aircraft part satisfying the removal threshold, transmitting a service alert to an operator of the given aircraft.
US11338939B2 Method and apparatus for producing at least part of an aircraft airframe
A method of producing a shim for use in an aircraft airframe (200) comprising: providing a plurality of component parts (202, 204) of the aircraft airframe (200); measuring a surface of each of the component parts (202, 204) and creating a digital models of the component part (202, 204) therefrom; digitally assembling together the digital models of the component parts (202, 204) thereby to produce a digital model (600) of at least part of the aircraft airframe (200); using that digital model (600), creating a digital model of a shim (604), the digital model of the shim (604) filling a gap between at least two digital models of component parts (202, 204) in the digital model (600) of at least part of the aircraft airframe (200); and producing a physical shim using the digital model of the shim (604).
US11338933B2 Acoustic honeycomb panel with integrated electrical heater
A noise attenuation panel comprises a sound absorbing honeycomb layer disposed between a perforated surface layer on an airflow facing side of the panel and a composite support layer on a second opposing side of said panel. The composite material support layer comprises an electrical heat source.
US11338931B2 High visibility panel latch
A high visibility panel latch may comprise a latch handle coupled to a latch mechanism, wherein the latch handle comprises a visibility feature. The visibility features may comprise a portion of at least a first face and a second face of the latch handle. The visibility features may comprise a painted channel.
US11338929B2 Forward engine attachment system for an aircraft engine comprising a direct coupling between the jet engine pylon and the engine
A forward engine attachment system for an engine of an aircraft, the forward engine attachment system including a jet engine pylon including, in the region of the forward part thereof, a front part having an attachment wall, and a forward engine attachment with a connecting rod system on either side of a median plane, wherein each connecting rod system is fixed in articulated manner by at least one first link point to the attachment wall and is designed to be fixed in an articulated manner by at least one second link point to a forward part of the engine. Such a forward engine attachment system thus includes a direct coupling between the jet engine pylon and the engine, allowing the production of an assembly that is less heavy and is easier to produce.
US11338928B2 On-board power supply network of an electrically propelled aircraft
A system for supplying electrical energy to at least one electrical load of an aircraft, this system including a main source of electrical energy connected to at least one electrical load through an electrical network, the system including a control device connected to the main source of electrical energy and configured to deliver a variable voltage level on the electrical network based on a predetermined voltage variation law depending on at least one parameter characterizing the altitude of the aircraft and according to the Paschen law with a predefined margin.
US11338915B2 Rotor systems and methods
An aircraft rotor system including a hub having a hub axis about which the hub is configured to rotate; a plurality of rotor blades configured to extend from the hub and rotate about the hub axis, at least one of the rotor blades rotatable about a respective pitch change axis; wherein the hub is configured to be rotated about the hub axis only by the plurality of rotor blades. Another aspect includes a method of operating the rotor system.
US11338914B2 Differential thrust vectoring system
A differential thrust vectoring system including a first thruster rotation assembly configured to rotate a first thruster relative of an aircraft, a second thruster rotation assembly configured to rotate a second thruster of an aircraft, and an actuator. The system is configured such that actuation of the actuator causes disparate rotation about the tilt axis of the first and second thrusters.
US11338911B2 Magnetic recovery systems and magnetic docking mechanisms for fixed-wing unmanned aerial vehicles
Example magnetic recovery systems and magnetic docking mechanisms for fixed-wing UAVs are disclosed herein. An example capture mechanism for an unmanned aerial vehicle (UAV) includes a first member attached to a capture vehicle, the first member having a first portion having a first shape and a magnetic portion; and a second member attached to the UAV, the second member having a second portion having a second shape, wherein the first member and the second member mutually self-align responsive to incidental contact of the first shape and the second shape, and the magnetic portion is to capture the second member.
US11338900B2 Aircraft plug door with in-plane load transfer capacity and methods of use
A plug door assembly for a pressurized aircraft is provided. The door assembly includes a surround and a door, and connector assemblies along the edges that act to transfer in-plane stresses directly across the fuselage opening via the door, as well as stops that react radial loads generated by cabin pressure. The door assembly obviates the need for a separate frame to transmit stresses around the perimeter of the fuselage opening.
US11338899B2 Joint for a metal airplane skin using metal matrix composite
A joint for a metallic skin structure includes a first end portion of the metallic skin structure and a second end portion of the metallic skin structure, wherein the first end portion and the second end portion of the metallic skin structure are secured together along a line of securement. The joint further includes at least one reinforcing fiber embedded within at least one of the first end portion of the metallic skin structure or the second end portion of the metallic skin structure extends orthogonal relative to the line of securement.
US11338897B2 Sheltering a balloon
A method for sheltering a balloon, a blimp, or airship. The method includes obtaining a first guideway by detachably attaching a first plurality of detachable rings to a first side of an outer surface of the balloon, placing a first rope into the first guideway by passing the first rope through the first plurality of detachable rings, attaching a first end of the first rope to a first point of a blanket, and pulling the blanket over the balloon by pulling a second end of the first rope in a first direction pulling the blanket over the balloon by pulling a second end of the first rope in a first direction.
US11338896B2 Aerospace balloon system and method of operation
A balloon system, preferably including a balloon and a payload. A balloon, preferably including a plurality of gores, a plurality of load members, and an apex fitting. A method of balloon system operation, preferably including deflating a balloon, and optionally including operating the balloon system in flight and/or landing the balloon system.
US11338894B1 Auxiliary low-speed marine steering associated with inverted snorkel for underwater engine exhaust
An improvement for inboard motor boats has a rigid exhaust conduit, a miniature rudder, and a rudder control system. The rigid conduit is provided for conduction of combustion gases exhaust outside the hull and has an aft facing outlet. The miniature rudder is pivotably mounted on the rigid conduit relative the aft facing outlet whereby combustion gases exhaust past the rudder. The rudder control system has a user interface inside the boat and has a control mechanism pivoting the rudder in response to inputs to the user interface.
US11338890B1 Line cutter apparatus
A line-cutter apparatus capable of being mounted on a tow cable is provided. A body is formed from two releasably coupled housings having a central bore when combined. A plurality of longitudinal grooves are formed in the body that divide the body into a respective plurality of longitudinal segments. Guard portions on the body correspond to the longitudinal segments. The body has fin portions that correspond to the longitudinal segments. Blades corresponding to the segments are received within the body and have a cutting edge that protrudes into one respective passageway of a longitudinal segment.
US11338889B2 Drive mechanism for bimini top system
A drive mechanism for a bimini top with a pair of bimini arms supporting the bimini top includes a motor, a worm screw coupled with the motor for rotation by the motor, and a driven gear coupled with the worm screw. One of the pair of bimini arms is connected to the driven gear, and the driven gear is configured for displacement between a stowed position and an extended position by operation of the motor. A pivot hub engages the driven gear via an intermediate hub, and the other of the pair of bimini arms is connected to the pivot hub. The pivot hub and intermediate hub are configured for displacement between a down position and an up position by operation of the motor through the driven gear and the intermediate hub. A first arc spanned by the driven gear between the stowed position and the extended position is greater than a second arc spanned by the pivot hub between the down position and the up position.
US11338884B1 Discoidal bicycle brake
A discoidal brake for a bicycle comprises a pair of discoids, each of which is mounted on a bicycle member laterally of a wheel rim, one on either side of the wheel. The discoid is pivotally mounted in levered relation on each pivot mount below adjacent and biased away from the wheel rim. A brake shoe is affixed to each discoid to allow camming of the brake shoe into the wheel rim facilitating braking. A control cable is affixed to a control member above the wheel with the control member being connected to the center of a yoke cable. The yoke cable is affixed to each discoid with yoke cable passed partway around the annular component on each discoid.
US11338883B2 Braking device for a personal mobility vehicle
A personal mobility vehicle, such as a scooter, includes at least one battery and motor for powering at least one driven wheel. The vehicle also includes a braking assembly configured to isolate the motor from the at least one driven wheel such that power is terminated from the motor to the at least one wheel in response to a user engaging a braking assembly of the vehicle. The vehicle can include a switch or position sensor that interacts with the braking assembly to initiate the isolation of the motor from the at least one driven wheel and the switch or position sensor preferably is inaccessible to the foot of the user.
US11338881B2 Quick assembly bicycle stem structure
A quick assembly bicycle stem structure includes a front fork stem, a handlebar stem having a zigzag-shaped slot opening formed at a lower end thereof that is received in an upper section of the front fork stem, the zigzag-shaped slot opening including a first vertical slot and a second vertical slot that are spaced apart in relation to one another, a pin bolt coupled to the front fork stem and extending into the zigzag-shaped slot opening of the handlebar stem, the pin bolt configured to travel within the zigzag-shaped slot opening and to enter the second vertical slot from the first vertical slot when the front fork stem is rotated relative to the handlebar stem, and a nut assembly received over the handlebar stem and configured to threadedly engage the upper section of the front fork stem.
US11338880B2 Personal transport vehicle
A personal transport vehicle is provided, which includes a front wheel assembly having a front rim and a front tire seated on the front rim, and a rear wheel assembly having a rear rim and a rear tire seated on the rear rim. The vehicle also includes a motor disposed within the rear rim of the rear wheel assembly and coupled to a mount of the rear rim, where the motor is configured to rotate the rear tire to cause movement of the personal transport vehicle. The vehicle further includes a frame coupled to the front wheel assembly and to the motor disposed within the rear wheel assembly, and a steering arm coupled to the front wheel assembly within the front rim for controlling movement of the front tire for steering the personal transport vehicle.
US11338879B2 Coupling mechanism for a vehicle body
A coupling mechanism for a vehicle body having mutually pivotable first and second frames comprises an axle fixed to the first frame, a rotating member fixed to the second frame and rotatably mounted around the axle, and a torsional resistance module that is actuated when the axle and the rotating member rotate relative to each other. The torsional resistance module includes two force magnifying mechanisms connected between the first frame and the rotating member. A buffering member is disposed between the force magnifying mechanisms. When the buffering member is pressed, a relative torsional resistance is provided between the first and second frames through transmission of the force magnifying mechanisms. The torsional resistance has a non-linear relationship with a relative rotational angle between the first and second frames.
US11338875B2 Fender assembly and vehicle including thereof
A vehicle includes a fender, a storage compartment, and a first retaining wall. The fender has an inner surface, an outer surface, and a through hole connecting the inner surface and the outer surface. The storage compartment has a bottom plate. The bottom plate of the storage compartment is located at a side of the outer surface of the fender and at least covers the through hole. The fender is located below the storage compartment in a top-bottom direction of the vehicle. The first retaining wall is disposed on the outer surface of the fender and surrounds at least a portion of the through. A portion of the first retaining wall is closer to a front of the vehicle than the through hole in a front-rear direction of the vehicle.
US11338874B2 Motorcycle rear fender structure
There is provided a motorcycle rear fender structure provided at a rear part of a motorcycle. A fender stay extends to an upper rear side from one side of left and right rear swing arms rotatably supporting a rear wheel. A rear fender main body covers an upper rear side of the rear wheel. A bulging portion bulges outward and rearward from the rear fender main body integrally. A wiring chamber is formed in the bulging portion. A partition wall is supported by the fender stay and provided in the rear fender main body. The partition wall is provided with a wiring hole for introducing an electrical wire connected to a lighting device into the wiring chamber. The fender stay is provided with a lower protruding portion extending in a left-right direction at a lower side of the wiring hole in the rear fender main body.
US11338873B2 Frame for an electric cargo bicycle
A frame for an electric bicycle, such as a long-tail electric cargo bicycle, is described. The bike frame, in some embodiments, includes cross members that connect a rear rack of the bicycle to a head tube of the bicycle via a seat tube of the bicycle. Via the multiple connection points, the cross members mitigate side to side movement, such as waggling, of the rear rack of the bicycle.
US11338868B2 Variable aerodynamic device
A vehicle, comprising: a vehicle body having a rear; and a variable aerodynamic device positioned at the rear of the vehicle body and being moveable between a lowered configuration and a raised configuration, the variable aerodynamic device comprising: a wing divided along its length into a middle region and outer regions to either side of the middle region, the wing having a reduced width within the middle region relative to the outer regions, and the wing forming part of an outer surface of the vehicle body when the variable aerodynamic device is in the lowered configuration and raised from the vehicle body when the variable aerodynamic device is in the raised configuration.
US11338867B2 Applique with deployable aerodynamic surface
A deployable applique assembly for a motor vehicle is provided. The assembly includes a housing having a wall with at least one through opening extending through the wall and a panel configured to overlie at least a portion of the wall when in a stowed position, with an outer surface of the panel being configured to form a smooth surface with a body panel of the motor vehicle. The assembly includes a drive link extending through the at least one through opening and having a first end operatively coupled to the inner surface of the panel and a second end. An actuator has a drive member operably coupled with the second end of the drive link, wherein the actuator is operable to selectively pivot the drive link to move the panel between the stowed position and a deployed position.
US11338865B2 Cab suspension systems and associated methods of manufacture and use
Vehicle cab suspension control systems are disclosed herein. In some embodiments, the cab suspension control systems can include front cab-to-frame mounts that include controllable elastomer-based isolators that can provide real time variable damping to improve ride quality and/or road holding and reduce cab roll in response to, for example, input from one or more cab and/or frame mounted accelerometers, position sensors, etc. Embodiments of the control systems described herein can utilize a single vehicle controller (e.g., an ECU) to control all of the cab suspension components (e.g., semi-active damping technologies, air spring technologies, etc.) employed on a vehicle to provide a single suspension control solution that can provide improved ride performance, road holding, etc.
US11338864B2 Vehicle body module connecting joint
A vehicle body module connecting joint for connecting a first body module to a second body module. Elongate profiles are arranged along facing edges of the first and second body modules, respectively. The profiles are clamped together by locking wedges arranged parallel to the profiles and connected by fastening means extending between facing profiles on the first and second body modules. The connecting joint includes a first profile arranged along a side edge of a first body module along a surface remote from the connecting joint and a second profile arranged parallel to and in form-fitting contact with the first profile along facing side surfaces. The assembled first and second profiles forming a single first dovetail section along a surface facing the connecting joint.
US11338861B2 Vehicle roof structure
A vehicle roof structure includes a roof bow and a stiffening member. The roof bow has a main section with a forward flange section, a rearward flange section and a middle section that extend in a lengthwise direction of the roof bow. The stiffening member has a panel portion with a plurality of forward projections extending from a forward edge of the panel portion and a plurality of rearward projections extending from a rearward edge of the panel portion. The plurality of forward projections are fixedly attached to the forward flange section of the roof bow and the plurality of rearward projections are fixedly attached to the rearward flange section of the roof bow. The panel portion of the stiffening member is located between the forward flange section and the rearward flange section of the roof bow.
US11338859B2 Land vehicles incorporating removable powertrain units, powertrain units, and methods therefor
Land vehicles, powertrain units for land vehicles, and methods of using land vehicles are disclosed. In certain embodiments, the land vehicles are provided as delivery vehicles and/or utility vehicles. A land vehicle includes a frame structure having a front cage that defines an operator cabin and a rear floor positioned rearward of the front cage. The frame structure supports a plurality of wheels to permit movement of the vehicle relative to an underlying surface in use of the land vehicle. An underside of the frame structure is disposed in confronting relation with the underlying surface.
US11338849B2 Method for analyzing and/or at least partially compensating steering wheel torsional vibrations
The disclosure relates to a method for analyzing and/or at least partially compensating steering wheel torsional vibrations, particularly during operation of a steering device in a vehicle, wherein at least one sensing signal is acquired and at least one interference characteristic variable which is correlated to the steering wheel torsional vibration is extracted from the sensing signal. It is proposed that during a monitoring time interval a change over time in the interference characteristic variable and a change over time in a wheel frequency which is correlated to a current wheel rotational speed characteristic variable is monitored and said changes are combined in order to analyze and/or to at least partially compensate steering wheel torsional vibrations to form a common evaluation dataset.
US11338847B2 Steer by wire type steering apparatus
Disclosed is a steer-by-wire steering apparatus. The steer-by-wire steering apparatus includes a locking portion configured to restrict rotation of a shaft which transfers a steering force or a steering reaction in certain conditions, an actuator which generates torque capable of overcoming a rotation-restricted state of the shaft, and a control portion which determines whether the rotation of the shaft is restricted by a malfunction of the locking portion even though the rotation of the shaft does not correspond to the certain conditions and controls the actuator to generate and provide the torque capable of overcoming the rotation-restricted state of the shaft to the shaft when it is determined that the restriction is caused by the malfunction.
US11338846B2 Detection signal correction method, motor control device, and electric power steering device
A detection signal correction method includes: calculating a rotation angle of a rotation shaft of a motor, based on a detection signal of a sensor; calculating a steering velocity of a steering shaft based on the rotation angle; calculating an error of the detection signal; and correcting the error of the detection signals when the steering velocity is equal to or greater than a steering velocity threshold value and the error of the detection signal is equal to or greater than an error threshold value.
US11338845B2 Method for operating an electrical power steering system of a transportation vehicle and electrical power steering system
A method for operating an electrical power steering system of a transportation vehicle wherein a steering wheel angle is pre-defined by a steering wheel as a measure for a desired wheel steering angle for at least one steerable wheel of the transportation vehicle, where an electrical power drive with an electric motor provides a steering support, and where a support torque of the steering support is reduced based on a damping function in response to the combustion engine of the transportation vehicle being started. Also disclosed is an associated electrical power steering system, to a computer program, and to a control appliance.
US11338842B2 Vehicle control apparatus
An ECU independently controls power supply to two winding systems in a motor on a per-winding-system basis based on current command values each calculated for a corresponding winding system in accordance with a target assist torque. When a first winding system fails, the ECU transitions from a first state in which the ECU causes the winding groups of the two winding systems to produce the target assist torque to a second state in which the ECU causes the winding group of the other normal winding system to produce the target assist torque. If the current command value for the normal winding system is equal to or below a current threshold value that is set with reference to zero or a value close to zero when the failed winding system recovers to its normal state in the second state, the ECU transitions from the second state to the first state.
US11338837B2 Transportation device and stabilizer for same
A transportation device and an automatic tilt stabilizer are disclosed herein. The transportation device has a structure with wheels joined by a shaft to a platform or chassis configured to support a basket, a mat, a seat and/or a tray. The automatic tilt stabilizer is configured to automatically stabilize the inclination of the platform or chassis, and includes a tilt sensor configured to detect an inclination of the platform or chassis, and a motor activated by a microcontroller configured to correct the inclination of the platform or chassis, so that the platform or chassis returns to a predefined inclination.
US11338834B2 Lowered bidirectional trolley
A bidirectional trolley (1) comprising a drawbar (Abstract2), two pivoting front wheels (6, 6′) a push handle (3), a loading and unloading plan (4) for a box (5) for moving items. The bidirectional trolley comprises a rotary system (10), placed in the rear portion of the trolley (1), and comprising two non-pivoting wheels (8′, 8″) placed on the same horizontal axis, a pivoting wheel (8) placed at 45° with respect to the other two non-pivoting wheels (8′, 8″) and a hook (12), configured for assuming a resting position in which it is completely retracted under the plan (4) between the two non-pivoting wheels (8′ and 8″), in order to permit to an operator to approach the most to the box (5) for moving items, for an easy unloading and loading of the box (5) itself.
US11338833B2 Electric rail vehicle
A Rail Drone can include: a payload interface, a drivetrain, and a rail platform(515). The Rail Drone can additionally or alternatively include any other suitable set of components. The Rail Drone can integrate a standardized payload interface and an autonomous electric road vehicle platform into a rolling stock architecture. The Rail Drone can be a stand-alone, payload-agnostic, motive element which can be independently or cooperatively capable of carrying heavy loads across long distances at various cruising speeds.
US11338832B1 System and method for railroad tie management
A Railroad Tie Management System is disclosed that can provide an efficient and organized method of inspecting and auditing ties in a rail system. Tie mark files can be retrieved by a client from a server or database in operable communication with the client, and upon instantiation of an inspection process governed by the system, an inspection information table and tie grid can be generated. The tie grid can operable to receive commands from a user, and the inspection information table is operable to automatically increment and decrement fields contained within in response to changes within the tie grid. The tie grid can also be configured to incorporate data from tie scans and serve the data to the client in a useful and user-friendly manner.
US11338831B2 Railcar having cold formed center sill with stiffness enhancing structure
A railcar comprising: a plurality of truck assemblies, each truck assembly having at least one wheel an underbody supported on said truck assemblies, said underbody including a cold formed center sill extending substantially the length of said railcar, wherein said center sill includes a top wall, a pair of side sections joined to the top wall by a pair of upper curved sections, bottom sections coupled to the side sections through curved connecting sections, wherein the center sill includes an upwardly extending stiffening longitudinal rib centered within the top wall.
US11338826B2 Parking assist system
A parking assist system includes: a control device configured to control a vehicle so as to move the vehicle autonomously from a current position to a target position; and an external environment sensor configured to detect an obstacle. During control of the vehicle to the target position, the control device is configured to recognize the obstacle present in a first area and a second area based on information from the external environment sensor. In a case where the control device recognizes the obstacle in the first area, the control device stops the vehicle, and in a case where the control device recognizes the obstacle in the second area and the obstacle in the second area is a moving object and/or a moving creature, the control device moves the vehicle in a decelerated state in which the vehicle is decelerated to a prescribed speed.
US11338824B2 Surrounding situation display method and surrounding situation display device
A surrounding situation display method of detecting a surrounding situation around a host vehicle with an autonomous driving function and displaying the detected surrounding situation, includes displaying, in a varying display bar that has a prescribed display frame and displays an indication position within the display frame in synchronization with movement of an attention target, the indication position having moved to one endpoint of the varying display bar as a timing when an action of the host vehicle is changed by the autonomous driving function.
US11338822B2 Vehicle and stop switch apparatus
A vehicle and a stop switch apparatus capable of accommodating various unexpected situations in a software operable vehicle. The vehicle is provided with a first operation section that allows operation of the vehicle without software, a second operation section capable of operating the vehicle by using software, a communicator that communicates with an external apparatus, and a stop switch that is provided physically and operable to stop operation of the second operation section without software.
US11338810B2 Vehicle yield decision
Upon determining a first vehicle is moving on a two-way road in a first direction of travel in an only lane of the two-way road, vehicle sensor data is input to a first neural network that identifies a yield area along the two-way road via image segmentation. A second vehicle is detected traveling toward the first vehicle on the only lane of the two-way road. Then, upon determining the first vehicle is to yield to the second vehicle, one or more vehicle components are actuated to move the first vehicle to the yield area.
US11338797B2 Hybrid vehicle and anti-rollover control method for the same
A hybrid vehicle for anti-rollover through active control of an engine and an anti-rollover control method for the same, may include detecting a roll angle of the vehicle, and when the detected roll angle is equal to or greater than a threshold roll angle, accelerating or decelerating, by a controller, the engine in a state in which the engine clutch is released depending on a direction of the roll angle.
US11338795B2 Vehicle control apparatus
A vehicle control apparatus includes: a clutch controller configured to switch an operation state of a clutch mechanism from a release state to an engagement state upon switching of a traveling mode from a motor traveling mode to an engine traveling mode; and a motor controller configured to control a traveling motor to suppress variation in torque upon starting of the engine. The clutch controller is configured to control the clutch mechanism to be brought into the engagement state at a first engaging speed when the engine is started on a condition that a revolution speed of the motor driving system is higher than a revolution threshold, and to control the clutch mechanism to be brought into the engagement state at a second engaging speed lower than the first engaging speed when the engine is started on a condition that the revolution speed is lower than the revolution threshold.
US11338792B2 Hybrid vehicle and method for adapting a power limitation of an internal combustion engine
A vehicle and method for controlling a vehicle having a traction battery and an internal combustion engine include adapting a power limitation of the internal combustion engine by sensing a currently supplied power level of the internal combustion engine and a current velocity of the vehicle, sensing an ambient temperature of the vehicle and determining an associated ambient-temperature-related weighting factor, sensing an ambient air pressure and determining an associated air-pressure-related weighting factor, determining a thermal load indicator as a function of a ratio of the sensed currently supplied power and the sensed current velocity as well as of the ambient-temperature-related weighting factor, the air-pressure-related weighting factor, and a vehicle-bodywork-related weighting factor, and limiting a maximum supplied power level of the internal combustion engine as a function of the determined thermal load indicator.
US11338790B2 Control device for hybrid vehicle
Since a maximum rotation speed is set to a lower value when a supercharging pressure from a supercharger is high than when the supercharging pressure is low, an engine torque is decreased at a relatively low engine rotation speed and the engine rotation speed is less likely to fall into a high-rotation state. Since the maximum rotation speed is set to a relatively high value when the supercharging pressure is relatively low and the engine rotation speed is less likely to fall into a high-rotation state, the engine torque is not decreased at a relatively high engine rotation speed and power performance can be easily secured. Accordingly, it is possible to curb a decrease in power performance due to a decrease in the engine torque and to prevent the engine rotation speed from falling into a high-rotation state.
US11338787B2 Hydraulic switch and hydraulic brake system
The disclosure provides a hydraulic switch including a casing, a first cable, a second cable, an electrically conductive piston and a first magnetic conductive component. The casing has a chamber and a liquid channel connected to the chamber. The first cable is disposed through the casing, and the first electrical connection portion of that is located in the chamber. The second cable is disposed through the casing, and a second electrical connection portion of that is located in the chamber. The electrically conductive piston movably is disposed in the chamber. When the electrically conductive piston is in an electrically connected position, the electrically conductive piston is in electrical contact with the first electrical connection portion and the second electrical connection portion. The first magnetic conductive component is configured to provide a magnetic force to move the electrically conductive piston toward an electrically disconnected position.
US11338780B2 Braking system
A braking system is provided. The braking system includes a plurality of brake fluid pressure generation devices provided in a front-side storage camber of a vehicle in which automated driving is enabled. The brake fluid pressure generation devices are provided on the same fluid pressure transmission route and include a non-electrically actuated brake pedal unit. The braking system includes an emergency stop button provided in a vehicle cabin, and an emergency brake circuit that generates braking force with use of the brake pedal unit in a non-energized state or in a case of transition to the non-energized state after the emergency stop button is operated.
US11338778B2 Braking system for autonomous car and setting method thereof
A braking system for an autonomous car is provided, including a car body, a pedal, a braking mechanism, a resistance ruler, a driving motor, a connecting member, a first micro switch, a second micro switch, and a control unit. The pedal is pivotally connected to the car body, the braking mechanism is connected to the pedal, and the resistance ruler is disposed on the pedal. The connecting member is connected to the driving motor and the pedal. The control unit is electrically connected to the driving motor, the resistance ruler, the first micro switch, and the second micro switch. When the pedal is in a first position relative to the car body, the pedal contacts and actuates the first micro switch. When the pedal rotates relative to the car body from the first position to a second position, the pedal contacts and actuates the second micro switch.
US11338776B2 Wiper blade device
A wiper blade device (10a; 10b; 10c) with at least one fluid channel (14a; 14b; 14c) which has at least one fluid output opening (16a, 16a′; 16b, 16b′; 16c, 16c′), in particular at least one nozzle element (50a, 50a′; 50b, 50b′; 50c, 50c′), to form a fluid output, and with at least one wind deflector unit (18a; 18b; 18c), on and/or in which the at least one fluid channel (14a; 14b; 14c) is arranged. The wiper blade device (10a; 10b; 10c) has at least one wiper blade end cap (12a, 12a′; 12b, 12b′; 12c, 12c′) which forms at least one end piece of the fluid channel (14a; 14b; 14c).
US11338772B2 Digital keys and systems for preventing relay attacks
Computer systems for training a machine learning model for preventing relay attacks. Including portable electronic devices capable of controlling the opening or closing, contactlessly, of an access to a road vehicle on the basis of a pretrained machine learning model. The general principle is based on the use of smartphones as a digital key for accessing a road vehicle. Machine learning is used to train a learning model capable of predicting the movement of a smartphone of this type as it approaches or moves away from the road vehicle. Subsequently, access to the road vehicle is authorized only when same receives the information on the movement of the smartphone.
US11338771B2 Wheel fastener alarm
A wheel fastener alarm assembly is provided having a fastener body with a first portion defining a wrenching surface and a cavity, and a second portion with a threaded portion to attach and detach from a wheel of a vehicle. A sensor array is disposed in the cavity of fastener body to detect an attribute of the fastener body and generate an output signal based on the attribute of the fastener body. An antenna connected to the sensor array to transmit the signal to a remote location. A cap is secured to the first portion of the fastener body and covers the wrenching surface and the cavity opening to define a capped fastener body.
US11338767B2 Seatbelt retractor
A spool 20 and a locking base 40 are connected through a torsion bar 70. A stop gear 82 and a positioning member 86 are engaged through threads with the male thread 42c of a locking base 40 so as to be separated from each other a predetermined distance. The locking base 40 and the torsion bar 70 are mounted to the spool 20 while the distance of separation between the stop gear 82 and the positioning member 86 is accurately set to a specified distance. When the tension of webbing increases due to the movement of a vehicle occupant in a vehicle collision and provides the torsion bar 70 with EA rotation while twisting the torsion bar 70, the stop gear 82 advances toward the positioning member 86 and comes into contact therewith.
US11338761B2 Gas generator with throttle member
Gas generator including means to provide a pressurized gas, a gas exit portion and a throttle member located in said gas exit portion, having one or more openings for the passage of said gas and being deformable by a gas flowing through said throttle when the pressure of said gas is above a predetermined pressure, to prevent or reduce gas flow.
US11338754B1 Extreme temperature safety device for vehicles
An improved vehicle safety device for activating an alarm when the temperature in the interior of a vehicle reaches an extreme value. The device includes a presence sensor for detecting the presence of a human or an animal in the interior of a vehicle and a temperature sensor for detecting the temperature in the vehicle interior. A controller is coupled to the presence detector, the temperature detector, and the vehicle ignition system for generating a hazardous-condition signal in response to an extreme-temperature condition in the vehicle when a human or an animal is in the vehicle and the vehicle engine is not running. An alarm module is connected to the controller for generating audible, visual, and wireless emergency-response signals when a hazardous condition is detected. The alarm module may also be further configured to create a door-unlocking signal.
US11338749B2 Bumper assembly for an automotive vehicle
An automotive vehicle includes a body having fore and aft portions. The vehicle includes a bumper beam coupled to the vehicle body proximate the fore portion and a heat exchanger disposed aft of the bumper beam. A fascia assembly is coupled to the vehicle body and extends about the bumper beam. The fascia assembly includes a fascia inlet configured to direct an airflow from the exterior of the fascia assembly to the interior of the fascia assembly. An energy absorption member is disposed between the fascia and the bumper beam. An air passage extends through at least one of the bumper beam and the energy absorption member. The air passage extends from an air passage inlet to an air passage outlet. The air passage inlet is positioned downstream of the fascia inlet with respect to the airflow, and the air passage outlet being positioned upstream of the heat exchanger.
US11338742B2 Bracket for in-vehicle device and holding device for in-vehicle device
A bracket for holding an in-vehicle device inside a window glass includes a base configured to be fixed to an inside surface of the window glass; right and left side portions protruding downward from the base; a locking member assembled so as to be movable between a first position and a second position; and at least one support portion configured to receive a supported portion provided in the in-vehicle device and inserted between the right and left side portions from a lateral direction while the locking member is located at the first position. When the locking member is moved to the second position while the supported portion is received by the support portion, the locking member is pressed against the supported portion so that the in-vehicle device is held in any of the front to rear direction and the up to down direction without rattling.
US11338740B1 Monitor mounting apparatus
A monitor mounting apparatus for use in connection with passenger vehicles such as aircraft, trains, and buses. The unique pivoting mechanism of the mounting apparatus permits lowering of the monitor in a manner that permits the top of the monitor screen to be visible even to the tallest of passengers.
US11338736B2 Car latch pedal
This invention relates to an auxiliary tool for automobiles, particularly a car latch pedal including a pedal. The pedal comprises a bottom clamp groove and a first connecting hole at one end; The bracket has a hook on one side of the end and a adjusting hole on the other side of the same end. The hook is hung on the car latch and the first pin is fixed on the first connecting hole. The adjusting hole of the bracket is inserted in the first pin, and the bottom clamp groove is positioned beneath the car latch, pressed on the car latch by using the first pin as the pivot. The car latch is positioned between the hook and the bottom clamp groove. The elastic block is fixed at the other end of the bracket. Small in size, the car latch pedal can be conveniently carried around by cars. Fixing the car latch at proper height will make it convenient to stably load or unload items at the car roof. The angle of the car latch can be adjusted to remain horizontal, avoiding damages to car paints or deformations of door frames.
US11338730B2 Lighting assembly for an interior of a vehicle, and vehicle and interior panel including the same
Lighting assemblies for interiors of vehicles, interior panels for interiors of vehicles, and vehicles are provided herein. In one example, the lighting assembly includes a backing structure having a first backing surface configured to face the interior when the lighting assembly is mounted in the vehicle. A bezel comprises a wall that extends from an outer edge portion to an inner edge portion. The inner edge portion is spaced apart from the first backing surface to define a gap and surrounds an opening that is configured to expose at least a portion of the first backing surface to the interior. A light source is disposed between the backing structure and the bezel and is covered by the wall. The light source is operative to produce light that passes from the light source through the gap onto the first backing surface and is reflected therefrom through the opening to the interior.
US11338728B2 Electronic device for installation in a motorized vehicle that warns of acceleration or deceleration
Electronic device comprising an electronic circuit that receives signals from a sensor and which are processed by a microcontroller, such that if an increase or decrease of time is detected between the signals sent by the sensor, they will be interpreted as an acceleration or deceleration respectively, being activated the acceleration or deceleration lighting devices as appropriate.
US11338727B2 Dynamic and proportional system for signaling braking maneuvers
The invention relates to a dynamic signaling system of the evolution of the braking maneuver that has visual proportionality with respect to the loss of speed of the vehicle, with fixed or programmed response sensitivity of the system in each braking maneuver, which enables visual proportionality and dynamic unambiguous representation of the variation of speed of the vehicle during braking. It can be applied with advantages to any type of vehicle, with an electric or hybrid combustion engine, with manual or automatic transmission. The system can be applied to both brake lights and the third brake light (high-mount brake light) indistinctly or jointly, further reinforcing the dynamic effect of attention and the transmission of information.
US11338726B2 Auxiliary spare tire brake light for vehicles
An auxiliary spare tire brake light is provided for a vehicle having a spare tire with a rim that has spokes and openings and that is secured on lugs at the back of the vehicle. The auxiliary spare tire brake light includes a support disc having a central portion and a peripheral portion. An array of openings is formed in the central portion of the support disc and the openings are positioned to fit over the lugs at the back of the vehicle for positioning the support on the lugs behind the rim of the spare tire. An annular race extends around the peripheral portion of the support and a plurality of lights in the form of LEDs is disposed in the race. The LEDs are arrayed in a closely spaced substantially continuous array around the support to form a ring of LEDs. A wire and electrical connector electrically connect the plurality of LEDs to the brake circuitry of the vehicle so that the LEDs are illuminated when the vehicle's brake pedal is depressed. A first portion of the ring of LEDs align with and project light directly through the openings in the rim of the spare tire to be seen from behind as an indication that the vehicle is braking. A second portion of the ring of LEDs aligns behind the spokes and reflects off of the backs of the spokes to silhouette the rim against the glow of the reflected light.
US11338724B2 Apparatus and method for generating illuminance information of vehicle
An apparatus for generating illuminance information of a vehicle and a method thereof are provided. The apparatus for generating illuminance information of a vehicle includes a camera configured to capture an image outside the vehicle, and a controller configured to generate vehicle external illuminance information that is provided for vehicle function control based on brightness of the image.
US11338723B2 Automotive lamp
An automotive lamp is capable of controlling a light distribution pattern PTN based on an image captured by a camera unit. The automotive lamp is capable of switching between multiple control modes designed with different combinations of the spatial resolution of the light distribution pattern PTN and the update speed of the light distribution pattern PTN.
US11338722B2 Control system for autonomous vehicle lighting
An automotive lighting control system is provided. A light-emitting diode (LED) system of an at least partially autonomous vehicle can include a first group of LEDs including cyan and amber LEDs, a second group of LEDs including cyan and at least one of red or amber LEDs, a third group of LEDs including cyan LEDs, and a controller configured to receive a first control signal indicating whether the at least partially autonomous vehicle is in autonomous drive mode or manual drive mode and cause the cyan LEDs of the first, second, and third groups LEDs to provide perceived cyan light when and only when the autonomous vehicle is in the autonomous drive mode.
US11338715B2 Shape memory alloy latch release mechanism for vehicle head restraint
An automotive head restraint apparatus includes a housing having a padded and upholstered exterior, the housing being rotatable about a lateral support tube that supports a lock plate having a lobe extending radially with a detent slot extending therein. A latch finger extends from a pivotable lock lever plate to releasably engage in the detent slot to latch the housing in the deployed position. A pull rod is secured to the lock lever plate, and is connected to a release lever arm at its other end. A shape memory alloy (SMA) wire loop is passed about a drive pulley that is supported by a reciprocally translatable slide. A drive arm extends from the slide to impinge on the release lever and raise the pull rod when the SMA wire loop is energized and contracted, thereby releasing the latch finger to rotate the housing to the retracted position.
US11338711B1 Lateral vibration isolator mechanism for vehicle seat back
A vehicle seat includes a first seat component such as a seat pan or seat frame, and a second seat component such as a seat back. The first seat component is rotatably coupled to the second seat component by a rotatable coupling, and a laterally oriented vibration isolator is positioned between the first seat component and the second seat component at the rotatable coupling. Transmission of vibration from the first seat component to the second seat component through the rotatable coupling is suppressed by the vibration isolator. In some cases, the vibration isolator is a quazi-zero-stiffness (QZS) isolator.
US11338709B2 Seat base assembly of a vehicle
A removable seat assembly for a vehicle, including a base assembly having a riser portion configured to support a seat; a frame structure coupled to and supporting the riser portion, the frame structure defining a first generally planar surface configured to support a floor section; a seat dolly coupled to the frame structure, the seat dolly including a plurality of wheels for moving the seat assembly from a first position to a second position; a floor base assembly defining a substantially planar surface for receiving the plurality of wheels of the seat dolly as the seat assembly is moved from the first position to the second position; and a mounting bracket configured to releasably lock the seat dolly to the floor base assembly.
US11338708B2 Seat height adjustment device for a vehicle seat
The present disclosure relates to a seat height adjustment device for adjusting the height of a seat cushion in relation to a seat frame, in particular, an upper rail, the seat height adjustment device comprising an actuating device, which may be, in particular, an electric motor, with a toothed pinion driven by the actuating device, and a toothed gear rack, the toothed gear rack comprising a hinge end for hinging onto the vehicle seat, and a front end including a gear rod region engaging with the toothed pinion, for adjusting the hinge end upon rotation of the toothed pinion. The present disclosure provides that the toothed gear rack is hot forged, the toothed gear rack comprises, between the hinge end and the gear rod region, a reinforced region, and the reinforced region comprises a profile.
US11338703B2 Seat unit
A seat unit includes a light receiving circuit configured to output a pulsed light detection signal in two levels depending on a light reception, a switch input circuit configured to output a pulsed on-off signal in two levels depending on whether a switch mounted on the seat is turned on or turned off, a logic circuit configured to output a turn-on signal upon receipt of the light detection signal in a level indicating the light reception and the on-off signal in a turn-on level, a light emitting circuit configured to emit light upon receipt of the turn-on signal, and a delay circuit configured to delay the light detection signal. The switch input circuit cuts off, upon receipt of the delayed light detection signal in a level indicating no light reception, the power supply from a battery to the switch and to output the on-off signal in the turn-on level.
US11338702B2 Control system and method for battery pack heating system, and battery pack heating management system
The application provides a control system and method for a battery pack heating system. The control system includes: a battery management system configured to acquire a state parameter of a battery pack, and send heating request information to a vehicle controller when determining the state parameter of the battery pack meets a preset heating condition; a motor controller configured to send, to the vehicle controller, feedback information indicating that a motor of the battery pack heating system is in a non-operating state, when determining the motor is in the non-operating state, and control, in response to a first control signal, a target upper bridge arm switch module and a target lower bridge arm switch module to be periodically turned on or off; and the vehicle controller configured to send the first control signal to the motor controller in response to the heating request information and the feedback information.
US11338701B2 Eco-friendly vehicle and method of providing guidance for charging amount
A method of providing guidance for a charging amount of an eco-friendly vehicle includes: predicting a driving energy for each section of a predicted travel route that is divided by a plurality of sections; calculating a battery input and output energy for each section based on the driving energy for each section; and determining a start SoC for minimizing a total change amount of a SoC that is sequentially changed in a section order when driving along the predicted travel route by applying a charge and discharge efficiency depending on a current SoC of a battery at each section to the battery input and output energy for each section.
US11338700B2 Battery swapping to manage in-vehicle battery communication
Battery swapping includes receiving a swap request for swapping a set of discharged batteries in a vehicle with a set of charged batteries at a charging station. Based on a battery swapping count provided by a user, the set of charged batteries including first and second subsets of charged batteries are selected from a plurality of charged batteries available at the charging station. At least one of a static ID or a dynamic ID is assigned to each charged battery. Each charged battery in the first and second subsets is configured as a master battery and a slave battery by integrating at least the respective static and dynamic ID in a corresponding battery management system of each charged battery, respectively, for facilitating in-vehicle battery communication. Further, the set of charged batteries is released from a charging and storing platform to a swapping platform for swapping.
US11338695B2 Variable power charging
The present invention provides a charging assembly for charging at least one electrically chargeable storage device, in particular an electrically chargeable storage device for driving an electrical vehicle, including multiple isolated DC power outputs, at least one outlet for connection to the at least one electrically chargeable storage device, at least one switching assembly for connecting the multiple isolated DC power outputs to the at least one outlet for connection to the at least one electrically chargeable storage device, whereby the switching assembly is adapted to connect at least two of the multiple isolated DC power outputs in series and/or in parallel to the at least one outlet. The present invention further provides a method for charging at least one electrically chargeable storage device, in particular an electrically chargeable storage device for driving an electrical vehicle, including the steps of providing multiple isolated DC power outputs, providing at least one outlet for connection to the at least one electrically chargeable storage device, and providing at least one switching assembly for connecting the multiple isolated DC power outputs to the at least one outlet for connection to the at least one electrically chargeable storage device, wherein the method includes an additional step of connecting at least two of the multiple isolated DC power outputs in series and/or in parallel to the at least one outlet.
US11338693B2 Method for charging a battery-operated vehicle
A method is provided for charging a battery-operated vehicle having a chargeable traction energy store and a system for autonomously guiding the vehicle with a charging vehicle having an energy generator and/or an energy store. The method forms at least one electrical coupling between the battery-operated vehicle and the charging vehicle via an autonomous driving manoeuver of the battery-operated vehicle and/or the charging vehicle. A charging of the traction energy store of the battery-operated vehicle occurs via the energy generator and/or the energy store of the charging vehicle during the driving of the paired battery-operated vehicle and charging vehicle.
US11338690B2 Power-supply and recharge groups
A power-supply and recharge group for an electric vehicle comprising: a first battery pack; a second battery pack; a first DC-to-DC converter; a second DC-to-DC converter; a low-voltage power-supply source; and a control unit configured to: detect a charge difference between a first and a second battery pack; transfer an electric current from a low-voltage power-supply source to the one of the first and second battery pack having a lower charge, until said charge difference is cancelled; connect the first and the second battery pack to one another in series and recharge them by means of a recharge station on the outside of the vehicle. A direct connection between the DC-to-DC converters can replace the auxiliary low-voltage source.
US11338688B2 Vehicle charging system
A vehicle charging system includes a second fitting body. The second fitting body includes a projection-side electrode holding unit which includes a projection, the projection holding a second electrode member and projecting in a facing direction, and an elastic body which supports the projection-side electrode holding unit in the facing direction and is elastically deformable in a compression direction which is one direction of the facing direction. The elastic body moves the projection-side electrode holding unit in the compression direction from an initial position by being compressed by a load in the compression direction applied to the projection-side electrode holding unit and moves the projection-side electrode holding unit to the initial position by being restored when the load is removed.
US11338686B2 Inductive power transfer pad
An inductive power transfer pad for a system for inductive power transfer to a vehicle includes a stationary part and a movable part which, in a resting position, rests on the stationary part and which is upwardly movable in a Z-direction relative to the stationary part in order to reach a higher position. The stationary part has a frame surrounding the stationary part on at least three sides, the frame having at an upper edge which is oriented towards the movable part. The upper edge has at least one first supporting surface on which the movable part rests when it is in the resting position, wherein the at least one supporting surface on the upper edge is an inclined surface. The movable part includes at least one first contacting surface which contacts the at least one first supporting surface when the movable part is in the resting position, with the first contacting surface fitting to the first supporting surface.
US11338684B2 Systems and methods for restricting power to a load to prevent engaging circuit protection device for an aircraft
A system for restricting power to a load to prevent engaging circuit protection device for an aircraft. The system includes an energy source of an aircraft. The system further includes a plurality of sensors configured to sense at least an electrical parameter of a load of the plurality of loads. The system further includes an aircraft controller configured to receive electrical parameter of a load of the plurality of loads from the plurality of sensors, compare the electrical parameter to at least a current allocation threshold, detect that the electrical parameter has reached the current allocation threshold, calculate a power reduction to the load, and reduce power from the at least an energy source to each load of the plurality of loads by the power reduction. The system further includes at least an electrical circuit of an aircraft, wherein the electrical circuit comprises a circuit protection device.
US11338682B2 Method and apparatus for recommending cluster UI design using distribution of design elements
Embodiments relate to an apparatus for recommending a cluster user interface (UI) design using a distribution of design elements including an eye position detection unit to detect an eye position of a driver from an image captured through a camera in a vehicle, a visible area determination unit to determine a visible area in a cluster based on the detected eye position, a position of the cluster in the vehicle and a position of a steering wheel, a cluster UI design search unit to search for a cluster UI design related to a shape of the determined visible area in a database, and a cluster management unit to recommend the found cluster UI designs to the driver and apply a cluster UI design selected by the driver from the recommended cluster UI designs to the cluster in the vehicle.
US11338679B2 Method of displaying residual capacity of secondary battery, display device, and motor-driven vehicle
A method of displaying a residual capacity of a secondary battery causes a computer of a display device to calculate a residual capacity of a secondary battery that stores electric power for driving a motor-driven vehicle based on an estimated value of an open-circuit voltage of the secondary battery storing the residual capacity calculated at the time of stopping of supply of electric power of the secondary battery and displaying the residual capacity at the time of stopping of supply of electric power on a display at the time of starting of supply of electric power of the secondary battery and subsequently displaying the residual capacity of the secondary battery on the display within a range with an upper limit value and a lower limit value with respect to the residual capacity at the time of stopping of supply of electric power.
US11338672B2 Axle assembly having a rotor bearing assembly
An axle assembly having an electric motor module, a drive pinion, and at least one rotor bearing assembly. The electric motor module may have a rotor. The rotor and the drive pinion may be rotatable about a first axis. The first rotor bearing assembly may extend between the drive pinion and the rotor.
US11338671B2 Hydraulic transaxle
A hydraulic transaxle of the present invention includes an axle, a hydraulic static transmission (“HST”), a center case that has pair of oil passages for circulating the hydraulic oil between the hydraulic pump and the hydraulic motor, and a gear mechanism that transmits an output of the HST to the axle. A case supports the axle and accommodates the HST while also forming an oil reservoir. A hydraulic motor of the HST includes a motor shaft, a cylinder block with a plurality of cylinders fixed to the motor shaft, a plurality of pistons inserted into the cylinders, a fixed swash plate abutted by the plurality of pistons, and a fixed swash plate holder that supports the fixed swash plate with respect to the case. The motor shaft of the hydraulic motor is supported by the center case and the fixed swash plate holder.
US11338663B2 Transmission and drive system of a motor vehicle
A transmission (2) of a motor vehicle includes a first input shaft (7) for a first prime mover (3), a second input shaft (8) for a second prime mover (4), and an output shaft (9). A first sub-transmission (5) includes the first input shaft (7) and a countershaft (11) coupled to the first input shaft (7) via a constant ratio. Gearwheels (16, 17, 18) are arranged on the countershaft (11), which mesh exclusively into gearwheels (12, 13, 15) arranged coaxially to the first input shaft (7). At least some of these gearwheels (14, 15) mesh into gearwheels (20, 21) arranged on the output shaft (9). Shift elements (A, B, C, D) are associated with the first input shaft (7) as well as with the countershaft (11), which provide either a gear with a first number of instances of gearwheel meshing or a winding-path gear with a second number of instances of gearwheel meshing. A second sub-transmission (6) includes the second input shaft (8) and is designed as a planetary transmission. A ring gear (22) forms the second input shaft (8) of the second sub-transmission (6). A carrier (23) is permanently coupled to the output shaft (9) and to a gearwheel (18) arranged on the countershaft (11). Shift elements (F, E) are associated with the planetary transmission, via which, a sun gear (24) is fixedly connectable to the housing or the planetary transmission is bringable into direct drive.
US11338660B2 Modular head assembly for an electric axle
A modular electric axle head assembly for a vehicle, including a gear assembly including a gear assembly housing defining a hollow portion therein, a first gear shaft having a first gear, a second gear shaft having a second gear and a third gear, wherein at least a portion of the second gear is drivingly connected to the first gear and the third gear, and at least a portion of the gear assembly is disposed within the hollow portion of the gear assembly housing; a motor assembly having an output shaft that is drivingly connected to at least a portion of the gear assembly; and a first mounting assembly including a portion integrally connected to the modular electric head assembly and a portion integrally connected to a support member of the vehicle, wherein at least a portion of the third gear is drivingly connected to a pair of drive shafts.
US11338658B2 Molded surface fastener
A vehicle cover assembly comprising; a flexible cover; one or more side rails; and a fastener assembly that is secured to a vehicle bed comprising; a cover fastener that is on one or more edge regions of the flexible cover; and a side rail fastener with one or more rows of fasteners comprising; a plurality of dual hooks on the base that releasably connect with the cover fastener of the flexible cover; and a plurality of spacers between the plurality of dual hooks.
US11338657B2 Sliding soft top
A panel top assembly for a vehicle including a controlled guide roller management system and install/release mechanism. A pivotal portion, that is rotatable between a closed position and open position, is coupled to guide assemblies slidably connected to guide track assemblies. Each guide track assembly includes a forward isolator assembly that restricts undesired movement/rattling of a roller in a guide track. A rearward isolator assembly restricts undesired movement/rattling of the roller in each guide track, and selectively keeps the roller in the track when the panel top assembly is in a down/open position. The rearward isolator assembly also includes an isolator that selectively allows an opening in the track for releasing the guide assembly from the track to move the panel top assembly to an open/stowed position, and, reinstalling the guide assembly to the track.
US11338656B2 Device for enhancing rigidity of vehicle body
A device for enhancing rigidity includes a pin holder configured to be provided at a door opening of a vehicle body or at a door provided at the door opening, and a rigid pin having a shape corresponding to the pin holder, the rigid pin configured to be provided at the door or at the door opening of the vehicle body and configured to be press-fitted into the pin holder when the door is closed at the door opening.
US11338654B1 Concealed automobile glare shield device with sliding groove
A sun visor device includes a sun visor including a receiving portion having two guiding grooves at two lateral sides thereof. A glare shield is slidably received in the receiving portion. A track device is disposed in the receiving portion and includes an outer track, a middle track slidably received in the outer track, an inner track slidably received in the middle track and fixed to a supporting rod. Two positioning members are disposed on two ends of the supporting rod, respectively. A pressing member is received in an outer end of each positioning member and is biased outward by a pressing spring to slidably abut an inner wall of an associated guiding groove. Each positioning member further includes a clamping unit fixed to two ends of the glare shield, such that the glare shield is jointly movable with the supporting rod.
US11338652B2 Zipper less removable windows for a folding SUV soft top
A zipper less removable window system having removable windows for use with a foldable, stowable roof for a vehicle. A plurality of attachment devices of the zipper less removable window system connect the windows to the foldable, stowable roof and to the vehicle without the use of zippers. The operator zipper effort caused by traditional windows is thereby eliminated and misalignment issues present with traditional zippered windows is eliminated or reduced. The stress placed on the portions of the windows connectable to the foldable roof during installation and removal, including around curved portions of the removable window, is eliminated or reduced.
US11338641B2 System for cooling vehicle electronic control unit with HVAC
A system for cooling a heat generating component of a vehicle. The system includes a blower of a vehicle heating, ventilation, and air conditioning (HVAC) system. An air duct extends from the blower to the heat generating component to cool the heat generating component.
US11338640B2 Front-mounted external cold air intake system for large refrigerated truck
The present invention relates to refrigerated trucks, more particularly to a front-mounted external cold air intake system for a large refrigerated truck, including a refrigerated compartment, an indoor chiller unit, an outdoor chiller unit, a front-mounted air duct, air outlets, horizontal louvers, folding elbows, windshields, blade control knobs, filters, covers, wind deflectors and blades. In the front-mounted cold air intake system, the front-mounted air duct introduces outdoor cold air into the refrigerated compartment, and transmits and distributes the cold air through the air outlets. Moreover, the air window structures formed by the horizontal shutters, the folding elbows and the windshields are used for discharging air, so as to stabilize the pressure in the refrigerated compartment. The system of the present invention uses outdoor cold air to effectively cool the compartment allowing for energy saving of the refrigerated truck.
US11338637B2 Electro-magnetic damper with air spring
A damper system for a vehicle is provided that includes a pressurized gas damper, electromagnetic actuator, and pressurized gas spring. The pressurized gas damper includes first and second working chambers that are fluidly connected by a flow control orifice. The electromagnetic actuator includes a stator assembly with a stator cavity and a magnetic rotor that is slidingly received in the stator cavity. The magnetic rotor is fixed to a damper tube that houses the second working chamber. The stator cavity and an end of the damper tube cooperate to define the first working chamber. The pressurized gas spring includes a bellows chamber that extends annularly about the damper tube. The damper tube includes an opening between the second working chamber and the bellows chamber.
US11338629B2 Tire pressure monitor with variable angle mounting
A tire monitoring system with mounting features on a housing provide for positioning through a wide range of angles. Accordingly, the system can be positioned on a variety of wheel rim/valve combinations. The tire monitoring apparatus includes two opposed wings provided on the housing to facilitate the range of positioning angles at which the housing can be positioned with respect to a valve base. Each opposed wing has a same exterior surface radius of curvature and the wings are clamped between a base plate and a clamp plate at the desired angle.
US11338627B1 Methods and systems for tire health monitoring
A method of monitoring one or more wheels of a vehicle is described. The method includes receiving first accelerometer measurements of a first accelerometer mounted on the vehicle's first wheel when the vehicle is moving during an interval of time, determining based on the first accelerometer measurements a first path followed by the first accelerometer when the vehicle is moving during the interval of time, determining based on the first path that the vehicle's first wheel is out of balance with respect to an axle of the vehicle's first wheel, and responsive to determining that the vehicle's first wheel is out of balance, transmitting to a user device a first alert that the vehicle's first wheel is out of balance.
US11338624B2 Tire and tire manufacturing method
A tire includes: a bead core; a bead filler which extends to an outer side in the tire-radial direction of the bead core; a carcass ply which extends from the bead core to another bead core, and folded back around the bead core; a first rubber sheet which covers a folding end of the carcass ply folded back from an inner side in the tire-width direction; and a second rubber sheet which covers the folding end of the carcass ply folded back from an outer side in the tire-width direction, in which an electronic component is provided between the first rubber sheet and the second rubber sheet.
US11338619B2 Pneumatic tire
Provided is pneumatic tire in which a land portion includes a width direction sipe extending in a tread width direction, the width direction sipe includes, in a cross section along a depth direction, a linear portion extending from an opening of the width direction sipe toward a bottom of the width direction sipe, and a bent portion connected to the linear portion, bending and extending from a connecting portion with the linear portion to the bottom of the width direction sipe, and the linear portion of the width direction sipe has a length in the depth direction increasing as the linear portion extends from a center portion of the width direction sipe in the tread width direction toward an end portion in the tread width direction.
US11338616B1 Wheel mechanism for autonomous mobile device
An autonomous mobile device may use a pair of main wheels and a caster assembly to provide mobility. The main wheels are driven by motors, providing steering and movement. Each main wheel may include a cover that conceals and protects a hub of the main wheel from the external environment. The covers may be held in place by elastomeric posts, allowing easy changeout. The caster assembly has a minimal overall height and a field replaceable caster wheel. The caster wheel may include a target that is detectable by a non-contact sensor to detect caster wheel rotation. The caster wheel may comprise an axle, caster wheel hub, and a pair of caster wheel endcaps on each end of the axle. A set of features on the caster wheel hub and each of the caster wheel endcaps provide a labyrinthian path that prevents debris from fouling around the axle.
US11338611B2 Method for manufacturing a light-alloy hybrid wheel including a front flange and a rim
The present disclosure provides a process for manufacturing a light-alloy hybrid wheel comprising the following separate operation phases: obtaining a front flange with an internal profile including a tire bead seat; obtaining a rim with an annular profile including a tire bead seat at a first end and a circular flank for assembly with a part of the flange at a second end; and assembling the flange and the rim to form a wheel. The annular profiles of the flange and the rim form exterior and interior sides of the wheel. Assembling the flange and the rim comprises welding the flank of the rim and the flange together by a single friction stir weld using a pin such that the weld is exposed at the exterior and interior sides of the wheel.
US11338610B2 Ribbon decoration device
A example ribbon decoration device includes a base structure having a first end, a second end, and a body. At least one end fastener attaches the first end of the base structure to the second end of the base structure for positioning the base structure around a portion of the tree, pole, fixture, window, doorway, or other object. A plurality of decorative ribbons are configurable between a rolled configuration for storage and an unrolled configuration for decorating. Ribbon fasteners are configured to attach a corresponding one of the plurality of decorative ribbons to the body of the base structure. The base structure is positioned on a tree, pole, fixture, window, doorway, or other object with decorative ribbons in the rolled configuration on the base structure, and the decorative ribbons are changed to the unrolled configuration for decorating the tree, pole, fixture, window, doorway, arch, or other object.
US11338609B2 Decorative film formed body, manufacturing method for a decorative film formed body, mounting method for a transfer base material, satin-plated preparation, container, casing, and vehicle interior/exterior member
Provided is a decorative film formed body being capable of exhibiting excellent metallic design presentation of satin plating with less color blur through decoration with use of a vapor deposition film, a manufacturing method for a decorative film formed body, a mounting method for a transfer base material, a satin-plated preparation, a container, a casing, and a vehicle interior/exterior member. The decorative film formed body includes: a base material; an adhesive layer; a vapor deposition layer; and a protection layer, wherein the vapor deposition layer has recesses and projections formed on a surface thereof, and wherein the adhesive layer includes scale-shaped fillers.
US11338607B2 Adjustable frames for use with hanging folders and related methods
Adjustable frames for use with hanging folders are disclosed herein. An example frame disclosed herein includes an a first end portion including a first side and a second side, a second end portion including a third side and a fourth side, the second end portion and the first end portion disposed within a plane, a first track disposed between the first side and the third side, and a second track disposed between the second side and the fourth side, the first track and the second track to enable the frame to move between a contracted position and an expanded position within the plane, the contracted position corresponding to a first distance between the first end portion and the second end portion, the expanded position corresponding to a second distance between the first end portion and the second end portion, the second distance greater than the first distance.
US11338605B2 Paper sheet processing apparatus
A paper sheet S is intermittently transported by a transport mechanism 6 and each processing unit 7, 8 operates while the transport mechanism pauses the transport operation. An information acquisition unit 9 obtains paper information from the paper sheet. A control unit 10 stores the paper information of the paper sheet to be processed for each processing unit, updates the data of the memory in a manner such that the paper information of the paper sheet associated with the previous processing unit is associated with the next processing unit every time the transport mechanism transports, and configures the settings of each processing unit for the next processing operation based on the paper information every time the processing operation of the processing unit is completed.
US11338604B2 Print media
A print medium can include a cellulose-based paper substrate with a first surface and a second surface opposite the first surface. The first surface can be treated with an electrically charged treatment layer. An ink-absorbing layer can be positioned on the electrically charged treatment layer. The ink-absorbing layer can include a polymeric binder and surface-activated fumed silica particles. The surface-activated fumed silica particles can include fumed silica particles that are surface-activated with charged multivalent aluminum salt and organosilane reagent. In further detail, an ink-receiving layer can be positioned on the ink-absorbing layer. The ink-receiving layer can include amorphous silica particles, alumina particles, or a combination thereof.
US11338602B2 Handle assembly for a stamp
A handle assembly adapted to be mounted on a driving member of a stamp has a knob body and an extending portion. The knob body has a bowl-shaped head, a central post, and a fixing seat. The extending portion has a ball joint, a collar, and a fixing plate. The ball joint is engaged with and encloses the bowl-shaped head, the collar surrounds the central post, and the fixing plate is mounted in a slot of the fixing seat. The extending handle is mounted on a top of the knob body firmly by the engagement between the ball joint and the bowl-shaped head.
US11338601B2 Recording condition determining method and recording device
A recording condition determining method executed by a recording device performing recording by a main scanning, in which while moving a recording head in a main scanning direction, dots are ejected from nozzles onto a recording medium, and a sub scanning, in which the recording medium is transported in a sub scanning direction. The method includes a patch recording step, the patch recording step being performed by recording patches at a plurality of different positions in the sub scanning direction by a plurality of types of overlap-processing under respectively different recording conditions, in a single recording job performed by the recording device. The method further includes a selection accepting step, and a determination step of determining, as a recording condition of the overlap-processing of an actual recording, the recording condition of the overlap processing corresponding to the patch selected in the selection accepting step.
US11338596B2 Image recording apparatus
An image recording apparatus includes a recording section which is provided over a transport passage for transporting a sheet in a transport direction and which has nozzles for discharging an ink onto the sheet; a platen which is provided under the recording section with the transport passage intervening therebetween and which has a plurality of ribs provided to support the sheet while being separated from each other in a widthwise direction of the transport passage perpendicular to the transport direction, the respective ribs protruding upwardly and extending in the transport direction; and a plurality of holding members which are provided to be positioned between the plurality of ribs in the widthwise direction of the transport passage over the platen on an upstream side in the transport direction from the nozzles and which abut against an upper surface of the sheet and press the sheet toward the platen.
US11338595B2 Print apparatus, method for controlling the same, and storage medium
A printer includes an ink ejection unit configured to eject ink to a print medium, a transport belt on which the print medium is mounted, a driving section configured to transport the print medium by moving the transport belt, a specifying section configured to specify a print head to be adjusted using a test pattern, markers configured to indicate a position of the print medium when the test pattern is printed on the print medium, and a driving controller configured to control the driving section. The driving controller controls the driving section in accordance with the print head to be adjusted specified by the specifying section so as to adjust a position of the print medium.
US11338594B2 Liquid discharging apparatus
A liquid discharging apparatus includes a transporting belt having an endless shape stretched over a plurality of rollers and configured to rotate while supporting a medium by a support face being a face on an opposite side from a contact face with the roller, to transport the medium in a transport direction, a liquid discharging unit configured to discharge a liquid onto the medium supported by the support face, and a drying section configured to dry, from a side of the contact face, the liquid adhering to the contact face.
US11338589B2 Droplet ejection device and droplet ejection method
[Problem] To provide a droplet ejection device and a droplet ejection method with which a liquid material can be continuously delivered to an ejection head when the liquid material is delivered between arbitrary tanks. [Solution] Provided are a droplet ejection device and a droplet ejection method using the droplet ejection device, the droplet ejection device comprising a droplet ejection head; a supply tank that is in communication with a first positive pressure source; a collection tank that is in communication with a first negative pressure source; a replenishment tank that is in communication with the supply tank and the collection tank; an opening/closing valve A that opens and closes a flow passage communicating between the supply tank and the replenishment tank; an opening/closing valve B that opens and closes a flow passage communicating between the collection tank and the replenishment tank; a switching valve that switches communication between the replenishment tank and a second positive pressure source and communication between the replenishment tank and a second negative pressure source; and a control device, wherein the control device has an ejection mode in which a liquid material is ejected from the droplet ejection head, a replenishment mode in which the liquid material is delivered from the replenishment tank to the supply tank while the liquid material is delivered from the supply tank to the collection tank, and a collection mode in which the liquid material is delivered from the collection tank to the replenishment tank while the liquid material is delivered from the supply tank to the collection tank.
US11338587B2 Fluid circulation apparatus and fluid ejection apparatus
According to one embodiment, a fluid circulation apparatus includes a first tank to store fluid to be supplied to a fluid ejection head, a circulation path including a first flow path portion to provide fluid from the first tank to a supply port of the fluid ejection head, and a second flow path portion to return fluid from a collection port of the fluid ejection head to the first tank, a bypass flow path to connect the supply port to the collection port outside of the fluid ejection head, and a pressure sensor configured to measure pressure of the bypass flow path.
US11338586B2 Logic circuitry
This disclosure describes integrated circuits which may be provided in logic circuitry packages and/or replaceable print apparatus components with print material reservoirs. An integrated circuit or logic circuitry package for a replaceable print apparatus component comprises an interface to communicate with a print apparatus logic circuit and at least one logic circuit.
US11338585B2 Box with alignment structures
A liquid supply, may include a bag and a box to maintain the bag therein, the box including a number of alignment structures formed along an edge of a first wall of the box to mate with a support element. A carton fold structure for a print liquid supply, the fold structure to support and hold a liquid bag including a liquid bag interface, the carton fold structure including multiple planes that, together, form a cuboid shape, each plane to form an outer wall of the carton fold structure, with edges between respective planes; a cut out in one of the edges, the cut out including: a channel extending inwards into a first plane to allow the liquid bag interface to pass through the first plane; and slots extending into the first plane between the channel and the edge associated with the first plane to align to a support element.
US11338579B2 Printing apparatus and recovery method therefor
A printing apparatus according to an embodiment of this present invention includes a printhead with an orifice for discharging ink, and a recovery unit configured to perform recovery of the printhead by driving a print element of the printhead to discharge ink from the orifice. The apparatus makes a setting for a request for discharge recovery by the recovery unit after initialization processing performed upon power-on of the printing apparatus, and controls the recovery unit to execute one of first discharge recovery and second discharge recovery in which an ink discharge amount is smaller than in the first discharge recovery in accordance with the setting before a start of printing by the printhead.
US11338578B2 Droplet inspection module and droplet inspection method
An inspection module is disclosed for inspecting a droplet from an ink jet head. The inspection module includes a sensor located under the ink jet head and measuring a distance between the droplet and the sensor in real time; a variable lens changing an operating distance based on the measured distance of the sensor; and a camera for capturing an image of the droplet. The inspection module further includes a droplet inspecting part inspecting the droplet image captured by the camera.
US11338577B2 Liquid ejecting apparatus and drive circuit
A liquid ejecting apparatus includes a print head that includes a first terminal and a second terminal, a first circuit substrate electrically coupled to the print head, and a second circuit substrate electrically coupled to the first circuit substrate, wherein the first circuit substrate includes a first coupling terminal electrically coupled to the print head, and a first electrolytic capacitor, wherein the second circuit substrate includes a constant voltage output circuit that outputs a constant voltage signal supplied to the second terminal, a first output terminal that is electrically coupled to the first circuit substrate, and a second output terminal that is electrically coupled to the first circuit substrate, and through which the constant voltage signal is output to the first circuit substrate, wherein the first electrolytic capacitor is electrically coupled to the second output terminal and the first coupling terminal.
US11338568B2 Storage device and printing system
A storage device is used in a printing device includes a storage section having a transfer stage for loading and unloading the exchange target object to and from the printing section, the storage section being configured to accommodate multiple placement sections, each for placing the exchange target object, and to store the exchange target object, a placement section moving section configured to move any one of the placement sections to the transfer stage, and a target object moving section disposed on the transfer stage, the target object moving section being configured to move between a retracted position allowing the placement section to pass and an abutting position abutting against the exchange target object on the placement section and to move the exchange target object in a loading/unloading direction while abutting against the exchange target object at the abutting position.
US11338566B2 Image control system and can decorator employing same
An image control system for a can decorator includes an electronic can decorator control assembly, a mechanical can decorator control assembly and a number of sensors. The electronic can decorator control assembly includes a programmable logic circuit and a number of modules. The mechanical can decorator control assembly is structured to be, and is, operatively coupled to at least one of an ink fountain ink application adjustment assembly, a ductor roll assembly duty cycle adjustment assembly, a printing plate cylinder assembly axial adjustment assembly or a printing plate cylinder assembly circumferential adjustment assembly. The electronic can decorator control assembly is structured to be operatively coupled to the mechanical can decorator control assembly. Each sensor in the number of sensors is structured to measure a can body applied image characteristic and to generate an image signal including data representing the can body applied image characteristic.
US11338565B2 Method for improving creep performance in elastic applications
A method and system of using a polyolefin-based, hot melt adhesive improves creep performance of elastic strands adhered to another substrate. Some deflection, greater than 1°, of the exit angle formed by a line normal to the axis of a neutrally-positioned applicator and the elastic strand extending from the applicator is introduced. Preferably, deflection of the entrance angle is also introduced and a head tilt angle is also provided. The use of deflection improves creep performance or allows for a reduced amount of adhesive to be used to achieve the same or similar creep performance. The elastic strands may be used to form a leg cuff in personal care products, such as diapers, and the substrate to which they are applied could be a polyethylene film or non-woven materials.
US11338563B2 Multilayer films and laminates containing slip agents
Provided is a coextruded multilayer film. The coextruded multilayer film has at least two layers, including a sealant layer and a second layer in contact with the sealant layer. The sealant layer contains (A) a first ethylene-based polymer having a density from 0.865 g/cc to 0.930 g/cc and a melt index from 0.5 g/10 min to 25 g/10 min; (B) an unsaturated primary fatty acid amide having a melting point of 100° C. or less; and (C) a diprotic fatty acid having a melting point greater than 100° C. and a decomposition temperature greater than 200° C. The second layer contains a second ethylene-based polymer. Also provided is a laminate containing said sealant layer.
US11338560B2 Functional fabric and manufacturing method therefor
Provided is a functional fabric including a base fabric layer; and an insulation flexible sheet attached to at least one surface of the base fabric layer. The insulation flexible sheet includes a first flexible base; and an insulation coating layer attached to at least one surface of the base. The insulation flexible sheet may additionally include a second flexible base on the insulation coating layer. Accordingly, the functional fabric may have effective insulation properties by using silica particles having pores in a small amount used, and may have excellent strength due to the strength of the silica particles. In addition, Manufacturing methods of an insulation flexible sheet and a functional fabric are provided.
US11338557B2 Method of manufacturing a timber composite, the timber composite obtained and decorative panels comprising such timber composite
A decorative panel including a substrate material and a decorative top layer. The decorative top layer is formed by at least one timber layer penetrated with a cured adhesive, and the timber layer has a wood structure with collapsed vessels having opposed walls, the opposed walls being glued together permanently by the cured adhesive.
US11338555B2 Laminated glass
Provided is laminated glass capable of preventing generation of a void in the interlayer film in an end part of laminated glass, and keeping the appearance of laminated glass excellent. Laminated glass according to the present invention is laminate glass including a first lamination glass member, a second lamination glass member, and an interlayer film containing a thermoplastic resin, and no void is generated in the interlayer film irradiated with light in an end part of the laminated glass after a first light irradiation test: “conducting 4 cycles each cycle including the process of irradiating the laminated glass with xenon light 180 W/m2 at a black panel temperature of 83° C. and a humidity of 50% RH for 144 hours, and dipping the laminated glass in pure water at 80° C. for 24 hours”, or a void is generated within a length of 1 mm or less inwardly from an end part of the interlayer film irradiated with light in the end part of the laminated glass after the first light irradiation test.
US11338554B2 Coloured laminated glass
A decorative laminated glass includes a first glass sheet, a second glass sheet, and a colored lamination interlayer between the first glass sheet and the second glass sheet. A coating is positioned between the first glass sheet and the lamination interlayer, and in direct contact with the first glass sheet. The coating is formed by the series of the following layers, starting from the surface of the first glass sheet: optionally, a first stack of dielectric layers; a layer based on titanium oxide having a thickness of from 5 to 70 nm; and optionally, a second stack of dielectric layers.
US11338548B2 Light weight gypsum board
This invention provides gypsum wallboards with a unique microstructure where the walls between voids are enhanced in thickness and strength to substantially improve the strength and handling properties of the wallboards. A method of making lightweight gypsum wallboards is also provided.
US11338546B2 Skin-covered foamed molded article
A skin-covered foamed molded article having excellent lightweight property, bending rigidity, and favorable dimensional stability, which includes: a skin material composed of a hollow molded body produced by blow-molding an extruded parison; and an expanded bead molded article located inside the skin material, wherein the skin material has an average wall thickness of from 1.0 mm to 5.0 mm, the skin material includes a glass fiber-reinforced polypropylene-based resin containing glass fiber in a range of from 5 mass % to 30 mass %, the glass fiber has a weight-average fiber length of from 0.4 mm to 1.5 mm, the expanded bead molded article includes a polypropylene-based resin, the peeling strength between the skin material and the expanded bead molded article is 0.1 MPa or higher, and the longitudinal linear expansion coefficient of the skin-covered foamed molded article (100) at from 23° C. to 80° C. is 7×10−5/° C. or lower.
US11338545B2 Laminate and method of producing same
A laminate comprising a plastic substrate (A); a hardened organic polymer layer (B) provided on a surface of the plastic substrate (A) and having a storage elastic modulus of from 0.01 to 5 GPa and tan δ of from 0.1 to 2.0 at 25° C. which are measured at a temperature elevating rate of 2° C./min by a dynamic viscoelasticity test stipulated in JIS K 7244; an organic/inorganic composite layer (C) provided on a surface of the hardened organic polymer layer (B) and containing covalently bound organic polymer and metal oxide nanoparticles; and an inorganic layer (D) provided on a surface of the organic/inorganic composite layer (C) and comprising secondary particles of ceramic or metal.
US11338537B2 Method and apparatus for transferring compartments to outer packagings provided for articles
The invention relates to an apparatus (1) for transferring compartments (3) to outer packagings that comprises at least one stock of compartments (3), at least one transport path (5) for outer packagings, and a working system that is designed to remove compartments from the stock and that can insert compartments (3) removed from the stock into a respective associated outer packaging. The working system is designed for removing a plurality of compartments (3) from at least one specific stock, for moving the plurality of compartments (3) in the direction of the at least one transport path (5) in a temporally overlapping manner, and for inserting the plurality of compartments (3) into a respective outer packaging of the at least one transport path (5).
US11338530B2 Method for producing optical component, method for producing product including touch sensor, optical component, and touch sensor device
A method for producing an at least partially transparent optical component including a laminate including fabricating a precursor laminate by bonding a transparent substrate and a transparent film to each other with a transparent photocurable adhesive layer interposed therebetween; curing the transparent photocurable adhesive layer by applying light thereto to change the precursor laminate into the laminate thereby, such that a shear modulus G′ of the transparent photocurable adhesive layer of the laminate measured under a condition of a temperature of 25° C. and a frequency of 1 Hz reaches a value within a range of 3×105 Pa≤G′≤3×107 Pa; and forming a flush and surface of the laminate by cutting the laminate in a thickness direction, such that the flush end surface includes respective cut surfaces of the transparent film, the transparent photocurable adhesive layer, and the transparent substrate.
US11338528B2 System for additively manufacturing composite structures
A system is disclosed for additively manufacturing a composite structure. The system may include a support, and a print head connected to and moveable by the support. The system may also include an encoder configured to generate a signal indicative of an amount of material passing through the print head, and a controller in communication with the encoder. The controller may be configured to selectively implement a corrective action in response to the signal.
US11338527B2 Heat seal bar assembly
A stitchless highly oriented polypropylene fabric bulk bag of the type that can hold 500 to 5000 pounds (226.7 to 2268 kilograms) of bulk material includes a highly oriented polypropylene fabric top, body and bottom, with a heat fused joint providing an air tight connection between the top and body, and another air tight heat fused joint connecting the body and bottom. A fill spout and discharge tube may also be provided with an air tight heat fused joint connecting the fill spout to the top and another air tight heat fused joint connecting the discharge spout to the bottom. Heat sealing machinery include heat seal bar assemblies that can self-align during heat-sealing to apply even pressure to all areas being heat sealed. A heating element is of single piece construction and can include end coupler portions as part of the single piece construction. Carrier plates used in a heat-sealing assembly line guide parts placement, provide quality checks for parts placement, and tooling set-up for machinery.
US11338526B2 Method for assembling thermoplastic tubes by induction welding
A method for assembling two tubes (1, 2) made from thermoplastic materials, that involves welding by heating two applied rotational contact surfaces of two parts of two tubes (1, 2), respectively, arranged end to end or overlapping coaxially (XX′). The method involves induction heating of at least one conductive welding element (4), arranged at the interface (3) between the two contact surfaces, by generating a magnetic field at said conductive welding element or elements, such that the melting of the thermoplastic materials constituting said contact surfaces produces a continuous and sealed weld at said interface on at least one closed loop along the entire perimeter of said interface.
US11338518B2 Method for operating at least one apparatus for manufacturing of three-dimensional objects
Method for operating at least one apparatus (1) for additively manufacturing of three-dimensional objects (2-4) by means of successive layerwise selective irradiation and consolidation of layers of a build material (5) which can be consolidated by means of an energy beam (6), wherein a communication interface (10) connected or connectable with the at least one apparatus (1) is adapted to receive at least a first data set (15-17) comprising object data from at least a first user (12-14), relating to at least one object (2-4) to be built, and at least a second data set (15-17) comprising object data from at least a second user (12-14), wherein a manufacturing process of at least two objects (2-4) is controlled dependent on the data sets (15-17) of the at least two users (12-14).
US11338516B2 Build material recovery for a three-dimensional (3D) printer
A build material recovery system for a three-dimensional (3D) printer can include a selective solidification device to create a 3D object using build material, a build processing device to separate the 3D object from unfused build material, a material separating and conditioning device to condition the unfused build material, and a material storage device to store the conditioned build material.
US11338514B2 Protective filament guide tube for additive manufacturing system
An additive manufacturing system includes a substantially moisture-impermeable barrier comprising a guide tube assembly for supplying filament from a filament supply to a print head in an extrusion-based additive manufacturing system, where the print head melts the filament and extrudes the melted filament to form a 3D part. The guide tube assembly includes an inner tube permeable to moisture and an outer tube that s substantially moisture impermeable. The inner tube has an interior passageway configured to receive the filament, and has a relatively low coefficient of friction to minimize drag force as the filament travels through it. The outer tube surrounds the inner tube and provides a substantially moisture-impermeable barrier around the inner tube.
US11338512B2 Method of forming channels within a substrate
Methods for forming channels within a substrate include molding a sacrificial component directly into the substrate and igniting the sacrificial component to deflagrate of the sacrificial component and form a channel in the substrate. The sacrificial component can include oxidizing agents such as chlorates, perchlorates, nitrates, dichromates, nitramides, and/or sulfates imbedded in a polymeric matrix, and the oxidizing agents can be 30 wt. % to 80 wt. % of the sacrificial component. The sacrificial component can further include one or more of unoxidized metal powder fuels, flammable gas-filled polymeric bubbles, one or more metallocenes and/or one or more metal oxide particles, one or more polymers with nitroester, nitro, azido, and/or nitramine functional groups, one or more burn rate suppressants such as oxamide, ammonium sulphate, calcium carbonate, calcium phosphate, and ammonium chloride, and non-combustible hollow bubbles and/or inert particles. The polymeric matrix can have a limiting oxygen index of less than about 30.
US11338511B2 Multiple image projection method for additive manufacturing
An additive manufacturing system, and associated methods, comprise an image projection system comprising a plurality of image projectors that project a composite image onto a build area within a resin pool. The composite image comprises a plurality of sub-images arranged in an array. The properties of each sub-image and the alignment of the position of each sub image within the composite image can be adjusted using a stack of filters comprising: 1) an irradiance mask that normalizes irradiance, 2) a gamma adjustment mask that adjusts sub-image energy based on a reactivity of the resin, 3) a warp correction filter that provides geometric correction, and 4) an edge blending bar at one or more sub-image edges.
US11338509B2 Device and method for manipulating particles
A device and method for manipulating particles is provided. The device generally includes a screen acting as a support for a structure formed by particles, which can be selectively deposited on a first substrate. The device can be included in a 3D printing system.
US11338505B2 Methods and apparatus for mobile additive manufacturing of advanced roadway systems
The present disclosure provides various aspects for mobile and automated processing utilizing additive manufacturing. The present disclosure includes methods for adding line features to a roadway surface. In some examples, the line features may include wires, conduits and electronic components. In some examples, the mobile additive manufacturing apparatus may create communication means into an advanced roadway in line features, which may be used for various communications including communications to and from autonomous vehicles. The communications may involve data related to the operation of systems of autonomous vehicles. In other examples, the line features may be dynamically colored with LED components.
US11338504B2 Online laser leveling detection method of 3D printer
The present invention provides an online laser leveling detection method of a 3D printer. The method comprises: (1), arranging a bar-shaped triangular reflecting prism and a bar-shaped photoelectric receiver; (2), fixedly mounting a laser emitter and a plane mirror on the side face of a printer head; (3), with the aid of a detection laser beam, fine tuning the mounting azimuths of an X-axis guide rail, a Y-axis guide rail, and the printer head till the motion levelness of the printer head is adjusted to meet requirements of the design accuracy of the printer; (4), with the aid of the detection laser beam, fine tuning the mounting azimuth of a printing platform till the mounting levelness of the printing platform is adjusted to meet the requirements of the design accuracy of the printer; (5), starting the 3D printing program; (6), in the printing process, detecting in real time whether a nozzle of the printer head generates faults including material blockage, shortage, and breakage. The present invention communicates detection signals of a laser detection system with a printer control system and designs the signal processing program to achieve detection of the motion levelness and the mounting levelness as well as monitoring of extrusion faults of the printer head.
US11338503B2 System for additively manufacturing composite structure
An additive manufacturing system is disclosed for use in fabricating a structure. The additive manufacturing system may include a support, and an outlet configured to discharge a material. The outlet may be operatively connected to and moveable by the support in a normal travel direction during material discharge. The outlet may include a guide, and a compactor operatively connected to the guide at a trailing location relative to the normal travel direction. The compactor may be moveable in an axial direction of the guide. The outlet may also include at least one cure enhancer mounted to move with the compactor relative to the guide. The at least one cure enhancer may be configured to expose the material to a cure energy.
US11338495B2 Device and method for controlling the throughflow of blow-molding fluid during the blow molding of containers
The disclosure relates to a device and a method for controlling the throughflow of blow-molding fluid during the blow molding of containers. It is the intention to provide a control device and a control method which permit a controlled or defined growth and a defined propagation of the container bubble formed by the expanding preform in the pre-blowing phase of the blow molding process without the specification of a specific setpoint value profile or of a setpoint value curve. The object is achieved by means of a control device and a control method having a proportional valve with a variable throughflow cross section, having an actuator for the operation of the proportional valve, having a means for detecting the position of the actuator, and having sensor means for detecting the valve inlet and valve outlet pressure, wherein a time for the attainment of the yield point for the preform, a container volume and a time period for the attainment of the container volume are predefinable, and, by means of a digital controller, during the pre-blowing phase, from the attainment of the yield point until the run duration, a calculation of control values for the operation of the actuator in order to attain the predefined container volume within the predefined time period is performed in automated cyclic fashion, and the actuator is operated in accordance with the calculated control values, wherein, in each calculation cycle, the calculation of the respectively next control value is performed taking into consideration the container volume attained prior to the respective calculation cycle and calculated on the basis of the previous actuator positions and the previous pressure profile.
US11338493B2 Two stage liquid blow molding method with heat sensitive ingredient
A liquid blow molding method molds a bottomed tubular-shaped preform into a liquid-containing container in which a content liquid is held. The liquid blow molding method includes: a first molding step of liquid blow molding the preform into a halfway shape by supplying, into the preform that has been heated to a predetermined temperature, a first liquid at a predetermined pressure through a nozzle unit; and a second molding step, performed after the first molding step, of liquid blow molding the preform by supplying a second liquid into the preform at a predetermined pressure through the nozzle unit.
US11338492B2 Method of making multi-layer blow molded article with functional, visual, and/or tactile effects
Method for making blow molded articles having a predetermined feature incorporated into the wall provided by variations in the thickness of the wall of the article corresponding to a predetermined pattern etched into the preform from which the article was formed.
US11338476B2 Plastic processing apparatus and related methods
The invention relates to macerator for processing a slurry, the macerator comprising an inlet configured to receive a flow of inlet slurry comprising particles having an average particle size of less than 20 mm, an outlet, two or more bodies that rotate relative to each other, each body comprising a plurality of apertures to define a flow path through each body, wherein the slurry traverses the flow path from the macerator inlet to the macerator outlet via the at least one aperture of each body to produce an outlet slurry.
US11338473B2 Filament, structural body, and method for manufacturing same
A filament can enable an arbitrary material to exhibit shape memory characteristics. A filament includes a linear core; and a covering layer covering the core; wherein: the core is formed with a shape memory material; and the covering layer is formed with a material different from the material of the core.
US11338470B2 Automatic machine for width gluing of wooden lamellas into laminated plates of optional dimensions and a method relating thereto
An automatic machine for width gluing of wooden lamellas into laminated plates of optional dimensions according to the invention consists of a press and a glue application device and enables fast continuous gluing of wooden lamellas of optional lengths, widths and thicknesses into laminated plates also of optional dimensions. The press is characterized by a modular construction, which consists of innovative supporting framework segments with intermediate work modules in a sequential string, which together enable transport of wooden lamellas, their pressing and gluing in the same plane within the entire construction of the press. Each work module consists of a work table assembly, a pressure shoes assembly and a segment pushers assembly. Within these assemblies, innovative constructions of segment pushers, long pressure shoes and short pressure shoes are characteristic.
US11338465B2 Band saw machine
A band saw machine is adapted for cutting a lumber, and includes frame body unit, a transport unit, a hold-down unit, a cutting unit and a drive unit. The transport unit includes an endless conveyor belt extending in a front-rear direction through the frame body unit for transporting the lumber. The hold-down unit includes an endless hold-down belt extending in the front-rear direction through the frame body unit. The endless conveyor belt and the endless hold-down belt are driven by the drive unit to rotate synchronously to carry the lumber to be cut by the cutting unit.
US11338464B2 Systems and methods for perforating flexible films, and related punching tools
A system for forming apertures in a flexible film is provided. The system includes a punching tool for forming apertures in a flexible film. The punching tool defines a through hole therethrough. The system also includes a support plate. The punching tool is configured to press the flexible film against the support plate to form the apertures.
US11338462B2 Providing a cutting area with web-like interleaver material
An apparatus for a single-track or multitrack provision of web-like interleaved sheet material at a cutting region in which products supplied on one track or on multiple tracks are cut into slices and interleaved sheets are introduced which are cut off from the provided interleaved sheet material in the cutting region, comprising an output device which is configured to eject at least one material web into the cutting region, wherein the output device comprises at least one driven feed roll and at least one counter-unit which forms a feed gap for the material web together with the feed roll.
US11338459B2 Clipper blade protector
A clipper blade protector enabling a user to enclose and protect the blades and teeth of clipper devices by incorporating a sheath body, a volume of cushion material, and a blade-receiving concavity. The sheath body extends between a cover end and an opening, wherein the blade-receiving cavity is formed within the sheath body between the opening and the cover end. The volume of cushion material is externally distributed along the sheath body between the cover end and the opening, thereby cushioning any external impacts against the enclosed portion of the clipper device. This protection is proposed to prevent breakage of the blades and teeth of the clipper device, saving both time and money in avoided replacements costs and maintenance.
US11338453B2 Joint structure for robot
A joint structure for a robot includes a first link and a second link rotatably coupled to each other through a joint part and a first linear-motion actuator and a second linear-motion actuator coupling the first link to the second link at a part separated from the joint part. The first linear-motion actuator and the second linear-motion actuator are each connected with the first link and the second link so as to be rotatable about two axes perpendicular to each other. When the second link is in an upright state, a first shaft member and second shaft members are disposed so that an angle formed by axial centers thereof becomes a right angle and the axial centers are oriented in a horizontal direction.
US11338451B2 Article of dishware gripping method with two adjacent teeth
Example systems and methods are described that are capable of gripping objects. In one implementation, a method involves identifying, by a processing system, an object to be gripped at a first location, commanding, by the processing system, a robotic actuator to move a gripper in a first direction so that the gripper makes contact with the object, wherein one or more teeth in a plurality of fingers associated with the gripper mechanically engage the object, and commanding, by the proceeding system, the robotic actuator to move the gripper in a second direction that is substantially opposite to the first direction, causing the gripper to grip the object.
US11338448B2 Substrate gripping hand and substrate transfer device including this substrate gripping hand
A substrate gripping hand which grips a substrate with a disc shape, includes a base plate, and a guide member provided at the base plate, and having a L-shape when viewed from a horizontal direction, the guide member having a shape in which a base end portion of a bottom surface has a horizontal portion and a first corner portion which is a corner portion formed by the bottom surface and an inner wall surface has a curve line shape.
US11338444B2 Robotic carrier device and system for preparing food products
A device having a platform configured to support the food products, a driving system configured to move the device, and a location detector configured to identify the location of the device within the area. A control system is configured to control the driving system based on the location of the device identified by the location detector, where the control system is configured to move the device along a primary path defined between a starting point and an ending point and to one or more fulfilment positions therebetween. The food products are received on the platform when the device moves to the one or more fulfilment positions.
US11338440B2 Robot system and calibration method
This robot system includes a robot, a tool which is attached to the robot, an imaging device, and a controller which controls the robot and the tool, and the controller is configured so that a distal end portion of the robot is placed at a plurality of calibration positions, the tool is operated at each of the calibration positions, images of light irradiated to an object or a trace left on the object due to tool operation processing are captured by the imaging device, and calibration is performed based on comparison between irradiation positions of the light or positions of the traces, which are in an image captured by the imaging device, and predetermined reference positions.
US11338437B2 Method and apparatus for health assessment of a transport apparatus
A method for health assessment of a system including a transport apparatus including registering predetermined operating data embodying at least one dynamic performance variable output by the transport apparatus, determining a base value (CpkBase) characterized by a probability density function of each of the dynamic performance variable output, resolving from the transport apparatus in situ process motion commands of the apparatus controller and defining another predetermined motion set of the transport apparatus, registering predetermined operating data embodying the at least one dynamic performance variable output by the transport apparatus and determining with the processor another value (CpkOther) characterized by the probability density function of each of the dynamic performance variable output by the transport apparatus, and comparing the other value and the base value (CpkBase) for each of the dynamic performance variable output by the transport apparatus respectively corresponding to the predetermined motion base set and the other predetermined motion set.
US11338433B2 Modular robot design
Systems and methods related to providing configurations of robotic devices are provided. A computing device can receive a configuration request for a robotic device including environmental information and task information for tasks requested to be performed by the robotic device in an environment. The computing device can determine task-associated regions in the environment. A task-associated region for a given task can include a region of the environment that the robotic device is expected to reach while performing the given task. Based at least on the task-associated regions, the computing device can determine respective dimensions of components of the robotic device and an arrangement for assembling the components into the robotic device so that the robotic device is configured to perform at least one task in the environment. The computing device can provide a configuration that includes the respectively determined dimensions and the determined arrangement.
US11338432B2 Bending muscle sleeve
A muscle sleeve includes: a sleeve-formed fabric; a plurality of first actuating muscles disposed next to each other and in parallel with each other on a first side of the sleeve-formed fabric; a plurality of second actuating muscles disposed next to each other and in parallel with each other on a second side of the sleeve-formed fabric; a plurality of fasteners that secure ends of the first and second actuating muscles to the fabric; and a crimp secured to the fabric.
US11338430B2 Article carrying robot
Included are a bottom portion having a traveling portion, a body portion having a first pillar portion and a second pillar portion extending in a vertical direction, respectively, from one end and another end in a horizontal direction of the bottom portion, and a top portion including one end connected to an end of the first pillar portion opposite to the bottom portion and including another end connected to an end of the second pillar portion opposite to the bottom portion, an article storage portion that forms an opening with the first pillar portion, the second pillar portion, the top portion, and the bottom portion in such a way that the opening penetrates the body portion, and fixing portions provided in the first and second pillar portions to sandwich the opening and pair up with each other, for fixing an article storage auxiliary instrument.
US11338428B2 Hand tool with a handle
A hand tool includes a handle, a press member, a shank body and multiple latch assemblies. The handle is formed with a receiving cavity and a locating hole in communication with the receiving cavity. The press member is movably disposed in the locating hole. The shank body is fitted in the receiving cavity and movable relative to the handle. The shank body is formed with multiple sockets. The latch assemblies are respectively mounted in the sockets. When the shank body is moved, (for example, slid or rotated) relative to the handle to make one of the sockets aligned with the locating hole, the latch assembly latches the shank body with the handle. When pressing the press member, the latch assembly unlatches the shank body from the handle, the shank body is movable relative to the handle.
US11338424B2 Insert bushing arrangement, breaking hammer and related method
An insert bushing arrangement of a breaking hammer, a breaking hammer and a method of supporting a breaking tool of a breaking hammer is provided. The insert bushing arrangement includes a bearing support inside which an insert bushing is mountable. Between the bearing support and the insert bushing is one or more intermediate material layers for preventing jamming of the components.
US11338418B2 Joint press adapter
A slip-on adapter that is adapted to be coupled to existing adapters that have already been developed. The slip-on adapter couples to existing adapters by positive retention on either the outside diameter or inside diameter of the existing adapter. For example, the slip-on adapter can include an O-ring that grips the outside diameter of the existing adapter that it is slipped onto. The slip-on adapter can also be used as a “flip adapter” with different geometries at both ends for use with two different size ball joints. This allows for less expensive adapters for new size ball joints by connecting to existing adapters, rather than requiring full machining of a new adapter.
US11338414B2 Bendable torque wrench
A bendable torque wrench includes: a shank; a tubular body whose front end is angularly displaceable with respect to the shank about an axis defined by a first pivotal connection end of the shank; an abutting block located on one side of the tubular body, a the front end of the abutting block has a convexly curved abutting surface; and a detent member whose front end is pivotally connected to a second pivotal connection end of the shank and whose rear end forms a convexly curved contact surface in elastic contact with the curved abutting surface of the abutting block. The torque wrench bends, or collapses, rapidly when the torque applied to the torque wrench reaches a preset torque value.
US11338411B2 Abrasive articles and methods for forming same
An abrasive article can include a body including a bond material and abrasive particles contained within the bond material. The bond material can include an organic material including a resin, particularly a phenolic resin. A methylene bridge can be present at para or ortho sites of aromatic phenolic rings. The bond material can include an average ortho to para substituent ratio for the methylene bridge within a range including at least 1.5:1 and not greater than 9:1, particularly, within a range including at least 3 and not greater than 6.9.
US11338401B2 Modular machine tool work holding system
A work holding clamp system for securing a workpiece to a work surface having a work surface T-slot arranged along an ‘X’ axis, comprised of a base plate secured to the work surface and having a plurality of T-slots, each of the plurality of T-slots are aligned with one of a plurality of axis including at least the ‘X’ axis and a ‘Y’ axis that is transverse to the ‘X’ axis. The work holding clamp system includes a workholding element selected from the group consisting of wedge clamps, pivot clamps and workstops, that may be secured within a T-slot of the plurality of T-slots provided in the base plate.
US11338398B2 Spacer grid welding fixture
A spacer grid welding fixture comprises a frame sized to receive an assembled spacer grid comprising a first set of parallel straps and a second set of parallel straps oriented orthogonally to the first set of parallel straps, the first and second sets of parallel straps interlocked together by slots cut into the straps. A first set of grid engagement bars is placed on a first side of the spacer grid with each grid engagement bar arranged parallel with the straps of the first set of parallel straps and engaging the straps of the second set of parallel straps. A second set of grid engagement bars is placed on an opposite second side of the spacer grid with each grid engagement bar arranged parallel with the straps of the second set of parallel straps and engaging the straps of the first set of parallel straps.
US11338397B2 Soldering material for active soldering and method for active soldering
A soldering material (1) for active soldering, in particular for active soldering of a metallization (3) to a carrier layer (2) comprising ceramics, wherein the soldering material comprises copper and is substantially silver-free.
US11338396B2 Techniques and assemblies for joining components
The disclosure describes example techniques and assemblies for joining a first component and a second component. The techniques may include positioning the first and second component adjacent to each other to define a joint region between adjacent portions of the first component and the second component, the joint region being coated with an adhesion resistant coating. The techniques may also include positioning a braze material in the joint region, heating the braze material to form an at least softened material, and cooling the at least softened material to form a mechanical interlock including the braze material in the joint region joining the first and second components. The braze material does not metallurgically bond to the joint surface.
US11338393B2 Manufacturing method of processed resin substrate and laser processing apparatus
A manufacturing method of a processed resin substrate includes: preparing a resin substrate including a resin layer and a metal layer that covers at least a part of one surface of the resin layer; and forming a through hole in the resin substrate by irradiating the resin substrate with pulsed laser light. In the forming of the through hole, an interval of irradiation of the pulsed laser light at each point on the resin substrate is 5 msec or more.
US11338392B2 Cutting method for forming chamfered corners
A cutting method for forming a chamfered corner includes a step of selecting a light pattern-adjusting module according to a pre-cut chamfer angle, a step of the light pattern-adjusting module emitting a laser beam to a substrate and thus forming a modified region extending in a thickness direction at the substrate, a step of the light pattern-adjusting module adjusting an axial energy distribution of a light pattern of the laser beam to vary an appearance of the modified region so as to form the modified region fulfilling the pre-cut chamfer angle, and a step of etching the substrate having the modified region to form a chamfered surface on the substrate by cutting the modified region from the substrate.
US11338391B2 Laser ablation for the environmentally beneficial removal of surface coatings
A laser-based method of removing a coating from a surface comprises directing a laser pulse to a first position on the surface, removing the coating from the first position by rapidly elevating a surface temperature of the first position using the laser pulse and thereby disassociating the coating from the surface and collecting the disassociated coating. In some embodiments, the coating comprises an environmentally harmful substance such as Hexavalent Chromium. In some embodiments, the coating comprises Diamond-Like Carbon (DLC), Vitrified Contaminant Material (CMAS). The disassociated coating is collected by a waste collector.
US11338388B2 Laser keyhole welding structure of aluminum material and laser keyhole welding method
Disclosed is a laser keyhole welding structure and a keyhole welding method of an aluminum material which stably suppress the generation of sputtering to ensure a reliable electrical connection and obtain a mechanically strong connection. To achieve this, a laser keyhole welding structure of an aluminum material is formed by welding an aluminum material element constituting an electronic component by irradiating a laser beam to the electronic component, in which a tapered portion spread angle (θ) of an upper portion of a welding nugget to be formed is 45° or less. Also disclosed is a laser keyhole welding structure of an aluminum material.
US11338378B2 Saw chain holder
A saw chain holder with a bar mounted sharpener for sharpening a chain includes a base plate and a cover plate removably attachable to the base plate. The base plate has a first base side surface, an opposite second base side surface, a groove extending into the first base side surface, and a base recess extending into the second base side surface. The cover plate has a first cover side surface and an opposite second cover side surface. The cover plate is movable into an assembled state in which the first cover side surface abuts the first base side surface, the chain is movable along the groove between the base plate and the cover plate, and the bar mounted sharpener is mounted in the base recess, bears against the second cover side surface, and is positioned over the groove.
US11338377B2 Power tool
A power tool includes a cutting unit configured to perform a cutting action, and a cutting action input unit configured to turn the cutting action on and off. The cutting action input unit is configured to, when the cutting action input unit is turned on, cause the cutting unit to move in a direction of an end position of the cutting action, and when the cutting action input unit is turned off, cause the cutting unit to stop moving in a case where the cutting action has not ended at a time when the cutting action input unit is turned off, and move in a direction of a standby position at which the cutting unit was located prior to a start of the cutting action in a case where the cutting action has ended at the time when the cutting action input unit is turned off.
US11338375B2 Portable manual vertical milling key duplicating machine
A portable manual vertical milling key duplicating machine comprising a body, a main axis component, a guide component, a clamping component, a feeding component, a power storage unit, a display unit and an electric control unit. This solution provides a pre-positioned precise guide mechanism and an adjustable handrail and is capable of improving the precision of key processing in multiple aspects and increasing stability during key processing. It has a compact structure with an upper/lower separate two-way sliding table configuration, thereby substantially reducing the machine size, and the body is divided into three areas, thereby ensuring good protection.
US11338369B2 Underfloor wheel set processing machine, in particular underfloor wheel lathe with adjustable track width
Represented and described is an underfloor wheel set processing machine, in particular an underfloor wheel lathe (1′) for reprofiling wheels and brake discs of wheel sets (20) of rail vehicles, comprising: a machine stand (3), a crossbeam (2) for bridging a workshop track (4) with at least two rails (4A, 4B, 4C) in the transverse direction, two roller carriers (7A, 7B), at least four friction rollers (8), at least one friction roller drive (9) to drive the friction rollers (8) and at least one axial guide roller (19) to axially guide the wheel set (20), wherein the machine stand (3) has a first part (3A) and a second part (3B), wherein the crossbeam (2) is supported on both parts (3A, 3B) of the machine stand (3), wherein the roller carriers (7A, 7B) are movably connected to the machine stand (3), and wherein the friction rollers (8) are rotatably supported on the roller carrier (7A, 7B). In order to adjust to wheel sets (20) with different track widths, it is proposed for the first part (3A) of the machine stand (3) and the second part (3B) of the machine stand (3) to be displaceable relative to one another in the transverse direction.
US11338363B2 Three-dimensional printing
At a print temperature, a layer (having a predetermined height) of metal build material particles is formed. Also at the print temperature, a fluid containing metal nanoparticles is selectively applied to at least a portion of the layer, and at a fluid loading that wets the portion through the predetermined height without saturating the portion. The metal nanoparticles are exposed to a sintering temperature that is higher than the print temperature and at least 500° below a melting point of the metal build material particles using a predetermined number of heating events taking place at a predetermined speed or for a predetermined time, and separated by a predetermined delay time, to bind the metal build material particles together to form a bound layer. A build material surface is cooled to or below the print temperature. The forming, selectively applying, exposing, and cooling are repeated to form a part precursor.
US11338360B2 Device and method for forming a metal matrix composite vehicle component
An exemplary method for making a metal matrix composite vehicle component includes: using a mold including male and female die portions having mold surfaces and a plurality of spacers; heating the mold to a casting temperature; placing a ceramic preform on the plurality of spacers, the ceramic preform being spaced apart from at least one of the mold surfaces by the spacers; closing the mold to form a mold cavity between the mold surfaces of the male and female die portions, the ceramic preform being disposed within the mold cavity; providing molten metal into the mold cavity; and pressurizing the molten metal to a casting pressure for a casting duration to infiltrate the ceramic preform thereby forming the metal matrix composite vehicle component.
US11338359B2 Composite part with external part cast around internal insert and method for producing the same
Composite parts (100) and methods of making the same are disclosed. A composite part may include an internal insert component (124) made of a first material. The internal insert component may be provided with surface features such as mechanical surface features or material surface features, on at least a portion of its surface. The composite part may further include an external part component (136) that is cast around at least a portion of the internal insert component, and is made of a second material different from the first material. The surface features of the internal insert component may help establish a bond within the composite part between the internal insert component and the external part component.
US11338352B2 Pressure expansion methods for heat exchanger manufacturing
Methods for expanding a tube to create a tight fit or an interference fit with one or more fins for the manufacture of a heat exchanger are disclosed. The methods can include providing an internal pressure to the tubes in a successive pulsing manner with each pulse having a short duration. The methods can include creating a temperature differential between the bend sections of the tubes and the straight sections of the tubes such that the bend section has a lower temperature than the straight sections. The methods can include creating an external pressure differential between the bend sections of the tubes and the straight sections of the tubes such that the external pressure acting on the bend sections is greater than the external pressure acting on the straight sections.
US11338351B2 Cam driven multi-output bodymaker
A can bodymaker includes a mounting assembly and a forming system. The forming system includes a plurality of forming assemblies, each forming assembly coupled to the mounting assembly, each forming assembly including a ram assembly with an elongated ram body, and a ram drive assembly operatively coupled to each forming assembly. The ram drive assembly is a direct ram drive assembly.
US11338350B2 Method for permanently fastening cams on a carrier tube
A method for permanently fastening a cam on a cam carrier may involve positioning the cam on the cam carrier in a predefined axial and angular position. By way of the positioning, an end face of the cam carrier is aligned with an end face of the cam. The method may also involve positioning a cam segment formed by the cam carrier and the cam in an assembly device. The cam carrier may then be deformed such that the cam is secured at least in a form-fitting or force-fitting manner against movement in an axial direction on the cam carrier. A deformation tool of the assembly device may be advanced in an axial direction onto the end face of the cam carrier, and the cam carrier may be deformed such that material of the cam carrier is forced outward in a radial direction against the cam.
US11338349B2 Loading dies in a press
Systems and methods for loading and/or unloading a die in a press are disclosed. A handling system for loading a die may include a linear sliding path between a supply position outside the press and a press position on the press base, configured to support a die such that the die is displaceable while it is supported on the path, and a robot configured to displace the die between the supply position and the press position along the linear sliding path. A method may include providing a robot for loading workpieces in the press, providing a linear sliding path between a supply position outside the press and a press position on the press base, placing a die in the supply position, and causing the robot to displace the die on the linear sliding path, from the supply position to the press position.
US11338346B2 Electrohydraulic forming device
An electrohydraulic forming device for forming a blank of material includes: —an electrohydraulic forming chamber, —at least one central electrode extending in a so-called longitudinal direction and comprising a first end arranged inside the electrohydraulic forming chamber, —a body provided with a bore for introducing each central electrode into the electrohydraulic forming chamber, the electrohydraulic forming chamber being partially formed by said body, —a mould, and —at least one peripheral electrode electrically insulated from each central electrode, arranged at a distance from and around the end of a central electrode, and extending in a transverse plane relative to said central electrode.
US11338342B2 Paintless dent removal tool, system and method
A paintless dent repair glue tab tool, system and method. The paintless dent repair glue tab tool, includes a pull member detachably connected to a support member. The pull member having a top, a threaded neck, and a bottom. The support member having a thick rigid center having an opening extending at least partially therethrough and a thin semi-flexible outer edge extending around the thick rigid center. The opening having a threaded metal insert molded therein and configured to receive a portion of the threaded neck of the pull member. The diameter of the pull member and the diameter of the support member transfer lifting power to a center portion of the paintless dent repair glue tab tool so as to pull up the dent at a peak thereby more efficiently removing dents from the surface of a vehicle.
US11338341B2 Cleaning plant for metal products
A plant for cleaning rolled metal strips provided with a superficial layer of oxide, the plant comprising unwinding means for unwinding at least one coil of rolled strip and pickling means for pickling said rolled strip; wherein there are provided measuring means for measuring the thickness of the superficial layer of oxide, arranged between said unwinding means and said pickling means. A relating cleaning method is also claimed.
US11338339B2 Cooling a roll of a roll stand
A cooling device (7) for cooling a roll (5) of a roll stand (1). The cooling device (7) includes a chilled beam (13) for receiving and discharging a coolant. The chilled beam (13) has multiple full jet nozzles (21) disposed on a discharge side (19) of the chilled beam (13), the side facing the roll (5) and extending parallel to a roll axis (17) of the roll (5). Through each of the full-jet nozzles, a jet of coolant having a nearly constant jet diameter can be sprayed from the chilled beam (13) towards the roll (5) in a discharge direction (23).
US11338334B2 Vehicle mounted garbage bin cleaning system including power takeoff
A vehicle mounted garbage bin cleaning system including power takeoff includes a pair of arms configured for lifting a garbage bin, the pair of arms rotatably coupled to a mount on the vehicle, a hopper configured for accepting the garbage bin when the pair of arms lifts the garbage bin into the hopper, at least one spray rod extending upwards from the hopper, said spray rod including a water nozzle, wherein when the pair of arms lifts the garbage bin into the hopper, the spray rod is situated within the garbage bin, a hydraulic pump mechanically coupled with a transmission of the vehicle, such that the transmission drives the hydraulic pump, a pressure washer pump mechanically coupled to the hydraulic pump, the spray rod is fluidically coupled with the pressure washer pump.
US11338333B2 Laser cleaning system
A laser cleaning system including a laser source, an energy-transferring optical fiber, a laser cleaning head, a coreless motor, a connection lens barrel, and a mirror.
US11338332B2 Cleaning station for optical elements
A cleaning station for an optical element is providing, including: an optical element holder configured to hold the optical element; a first drive configured to rotate the optical element holder around a rotation axis coinciding with an optical axis of the optical element when held by the optical element holder; a cleaning nozzle configured to project a cleaning jet of a cleaning liquid towards the optical element; and a separate drying nozzle configured to project a drying jet towards the optical element, the cleaning nozzle and the drying nozzle being configured to move in order to direct the cleaning jet and the drying jet, respectively, successively to different locations on the optical element.
US11338331B2 Sorting installation and method for the sorting of objects
A sorting installation sorts objects and contains a sorter for conveying objects and also an end station facility accepting objects. The sorter is configured to bring at least a few of the objects conveyed on the sorter in an object introduction direction, which is different from a local direction of object conveyance of the sorter in an area of the sorter adjoining the end station facility, into the end station facility. In order to make possible a fine distribution of the objects that is favorable in terms of the effort involved, the end station facility has a first object store, a second object store and also a transport facility. The transport facility is configured to transport the objects brought by the sorter into the end station facility optionally along a first transport path to the first object store or along a second transport path to the second object store.
US11338325B2 Touch feedback and sensing device
A touch feedback and sensing device includes a circuit board, a piezoelectric ceramic actuator on the circuit board; and at least one strain sensor on the circuit board. The piezoelectric ceramic actuator includes a piezoelectric ceramic block, a cathode and an anode on the piezoelectric ceramic block. Different voltages are applied to the cathode and the anode to vibrate the piezoelectric ceramic block. The circuit board vibrates with vibration of the piezoelectric ceramic block. The at least one strain sensor is configured to detect and monitor vibration of the circuit board.
US11338323B2 Method of improving adhesive strength between heterogeneous materials of metal and resin
A method of attaching heterogeneous materials comprising pretreating the surface of a metal plate with an aromatic compound containing a pyrogallol group to bind the pyrogallol group to the surface of the metal plate and coating the pyrogallol-group-bound metal plate with a polymer resin, thereby greatly improving the adhesive strength between the metal plate and the polymer resin.
US11338305B2 Hydrocyclone overflow outlet control device
The chamber (29A) of the overflow outlet control device (21A) has an inner circumferential surface which, when viewed in cross-sectional plan view, is generally in the shape of a volute, for directing material entering the chamber (29A) via the circular inlet (34) at the base portion (36) tangentially outward towards the discharge outlet (22A) located in the side wall (38). The top wall region (40) of the interior wall of the chamber (29A), a side wall portion (32) and base portion (36) together seamlessly form the chamber (29A) which is curved in shape internally. When material flows in use between the inlet (34) and the discharge outlet (22A), and passes through the central chamber (29A), it encounters no sharp corners or edges, but just smoothly curved or rounded interior wall surfaces. The top wall region (40) of the chamber (29A) also features a protruding flow control formation (42) which is joined or formed therewith, and which is arranged to extend into the chamber (29A), being directed face towards the inlet (34) such that in use the flow of material into the chamber (29A) via the inlet (34) directly encounters the formation (42).
US11338301B1 Pan for separating granular material
A pan for separating granular material may include a bottom wall and a sidewall. The sidewall may have an upper perimeter and a lower perimeter, and the lower perimeter may be coupled to the bottom wall so that the bottom wall and sidewall are watertight or otherwise configured to hold a volume of water. Preferably, the upper perimeter may be larger in dimension than the lower perimeter. A baffle plate may be coupled to the sidewall so that the baffle plate may be positioned between the upper perimeter and the lower perimeter. The baffle plate may have a proximal surface and an opposing distal surface, and portions of the proximal surface may contact the sidewall. A pocket may be formed between the bottom wall, the first baffle plate, and a portion of the sidewall that is between the bottom wall and sidewall.
US11338300B2 Cell wall or cell membrane disrupting device, and method of using the same
Provided is a cell wall or cell membrane disrupting device whereby cell walls and/or cell membranes of microorganisms, algae and the like contained in organic sludge and the like are disrupted, the device comprising a fixed disc, a rotating disc, a rotating shaft for driving of the rotating disc, a pressure reducing means and a housing, wherein at least one pair of the fixed disc and rotating disc are disposed facing each other, the center section of the fixed disc has a hollow section that is larger than the outer diameter of the rotating shaft passing through the center section, shearing force generated between the rotating disc and the fixed disc is applied to a target fluid having a water content of 89% or higher that has been loaded into the device, and the pressure inside the cell wall or cell membrane disrupting device is reduced to no greater than −0.08 MPa by the pressure reducing means. The device can contribute to increasing biogas, reducing sludge, culturing of algae, plant cultivation and culturing of marine products, and also to separation of CH4 and CO2, for example, as resources.
US11338295B2 Thermocycling system and manufacturing method
A system for thermocycling biological samples within detection chambers comprising: a set of heater-sensor dies, each heater-sensor die comprising a heating surface configured to interface with a detection chamber and a second surface, inferior to the heating surface, including a first connection point; an electronics substrate, comprising a first substrate surface coupled to the second surface of each heater-sensor die, an aperture providing access through the electronics substrate to at least one heater-sensor die, and a second substrate surface inferior to the first substrate surface, wherein the electronics substrate comprises a set of substrate connection points at least at one of the first substrate surface, an aperture surface defined within the aperture, and the second substrate surface, and wherein the electronics substrate is configured to couple heating elements and sensing elements of the set of heater-sensor dies to a controller; and a set of wire bonds, including a wire bond coupled between the first connection point of at least one of the set of heater-sensor dies and one of the set of substrate connection points.
US11338290B2 Sorting biological and non-biological moieties using magnetic levitation
Systems and methods for levitating populations of moieties, cells, or other such units using one or more magnets in a microfluidic environment are provided. These systems and methods may be used to, for example, separate or sort heterogeneous populations of the units from one another, to assembly a multi-unit assembly during the levitating of the units, and to evaluate samples at the point of care in real-time. These systems and methods may also utilize a frame that enables an imaging device, such as a smartphone, to capture the units in real time as they are manipulated in the system.
US11338289B2 Microfluidic device
Microfluidic device comprising a tank (6) supplying a microchannel (2) with a first fluid (S), and a circuit (8) in which a flow of a second fluid can be established without contact with the microchannel (2). The circuit (8) passes through the tank (6) or is connected to the tank (6) by a pipe (30). The circuit (8) comprises a first on/off valve (12) mounted in parallel with a first proportional valve (11), these first valves (11, 12) being controllable so as to modify the pressure applied in the tank (6) to the first fluid (S) by the second fluid.
US11338288B2 Peristaltic pump and analyzer for testing a sample
A peristaltic pump and an analyzer for testing a biological sample, wherein the pump includes a pump head that is constructed as a screwless assembly, wherein the pump includes a bayonet and/or a beam coupling, and/or wherein rollers of the pump are configured to be pivoted about corresponding pivot axes that intersect with the roller axes.
US11338286B2 Detection of microscopic objects
A substrate for use in manufacture of a production master plate for production of a detection disc for carrying samples in an apparatus for detection of microscopic objects in a fluid, the substrate having a channel and separate focus structure, wherein the focus structure is a groove.
US11338284B2 Microfluidic system and microfluidic method
A microfluidic system and method are disclosed. The microfluidic system includes: a first base substrate; a second base substrate opposite to the first base substrate; a first electrode on a side of the first base substrate close to the second base substrate; and a second electrode on a side of the second base substrate close to the first base substrate, the first base substrate and the second base substrate forms a cell, the cell is configured to receive a liquid to be detected, the first electrode and the second electrode are configured to drive the liquid to be detected during a first time period, and output a capacitance signal between the first electrode and the second electrode during a second time period.
US11338282B2 Tube assembly for dripping to diagnostic strip and extracting gene fragment
The present invention relates to a tube assembly for dripping. According to an embodiment, a tube assembly for dripping includes a tube (100) having a hole (H) at an upper portion thereof, and a filter tip (200) having a tip (210) including, an insertion part (211) inserted into the hole (H) of the tube (100) and, an expansion part (212) connected to the insertion part (211) and having a diameter that is larger than that of the hole (H), and a discharge pipe (213) connected to the expansion part (212) and acting as a passage, through which a solution (S) stored in the interior of the tube (100) is discharged, wherein a discharge adjusting part (213a) having a discharge hole (h) having a predetermined diameter (d1) is formed in the interior of the discharge pipe (213) that is spaced apart from a lower end of the discharge pipe (213) by a predetermined distance.
US11338278B2 Light treatment of chromium catalysts and related catalyst preparation systems and polymerization processes
Catalyst preparation systems and methods for preparing reduced chromium catalysts are disclosed, and can comprise irradiating a supported chromium catalyst containing hexavalent chromium with a light beam having a wavelength within the UV-visible light spectrum. Such reduced chromium catalysts have improved catalytic activity compared to chromium catalysts reduced by other means. The use of the reduced chromium catalyst in polymerization reactor systems and olefin polymerization processes also is disclosed, resulting in polymers with a higher melt index.
US11338272B2 Catalyst capable of directly decomposing urea and method for urea decomposition using the same
The present disclosure relates to a catalyst for directly decomposing urea, a method for preparing the same and a system for decomposing urea including the same, whereby the efficiency of decomposing urea to ammonia may be improved while preventing the formation of a byproduct such as biuret at temperatures of 200° C. or below by controlling the oxygen composition of the catalyst including titania and ceria.
US11338268B2 Composition for mineralizing carbon dioxide and nitrogen oxide gases and uses thereof
The invention relates to a composition for mineralising carbon dioxide and nitrogen oxide gases, which comprises a mixture of magnesium (between 1 and 25%), iron (between 1 and 23%), calcium monoxide (between 1 and 25%), titanium dioxide (between 0.1 and 11%) and silicon dioxide (between 16 and 75%), with a particle diameter between 100 nm and 4000 μm. The composition causes the mineralisation of carbon dioxide (CO2) and of the gaseous chemical compounds known as “nitrogen oxides” (NOx) in the atmosphere. This composition can be added or mixed as an additive in paints, dyes, resins and elastic polymers (gum and natural rubber) in parts with wear, and for any type of covering.
US11338267B2 Water-absorbent resin particle
Disclosed are water-absorbent resin particles comprising a crosslinked polymer comprising a monomer unit derived from a water-soluble ethylenically unsaturated monomer, wherein an artificial menstrual blood volume increase rate as measured in an artificial menstrual blood swelling test conducted in the order of i), ii), and iii) is 70% or more. i) putting 1.0 g of water-absorbent resin particles into a measuring cylinder with an inner diameter of 27 mm. ii) injecting 10 ml of artificial menstrual blood into the cylinder at once to swell the water-absorbent resin particles. iii) measuring a volume (A) of the swollen water-absorbent resin particles after 60 seconds from the injection and calculating an artificial menstrual blood volume increase rate according to Equation (I) below. Artificial menstrual blood volume increase rate (%)=(A−B)/B×100 . . . (I), A . . . Volume (ml) of swollen water-absorbent resin particles, B . . . Volume (ml) of injected artificial menstrual blood.
US11338262B2 Method for improving reaction yield
In a catalytic reaction, after a reaction product leaves a catalyst bed, an inert substance with a low temperature is sprayed, and through heat absorption and vaporization processes of the inert substance, the temperature of the reaction product drops rapidly when staying in a catalyst cushion layer at a discharge end of a fixed bed reactor, or in a space formed by the catalyst cushion layer at the discharge end of the fixed bed reactor and a reactor head, or in a space formed by a tube plate at the discharge end of the fixed bed reactor and the reactor head. The residence time of the reaction product is shortened due to the entrance of the inert substance in a gaseous state.
US11338261B1 Fenton reactor with gaseous agitation
A Fenton apparatus of the present disclosure includes a reactor vessel, gas injection inlets that allow ejection of aeration coolant perpendicular to axis of the reactor vessel to agitate a reaction composition present in the reactor vessel under vortex conditions, a jacket cooling loop encasing the reactor vessel to allow circulation of a jacket coolant selected from a group consisting of forced air, nitrogen gas, and water, a coil cooling loop coiling around the reactor vessel to allow circulation of a coil coolant selected from a group consisting of forced air, nitrogen gas, water, and carbon dioxide. Multiple programmable solenoid valves are provided to individually control injection of the aeration coolant, the jacket coolant, and the coil coolant. A controller is provided to communicate with a temperature sensor and each programmable solenoid valve.
US11338256B2 Automatic sealant production line
Disclosed is an automatic sealant production line, including a sealant preparation apparatus and a packaging apparatus. The sealant preparation apparatus includes a material storage device, a liquid storage device, a material sending device, a lateral material feeding device, a first-order screw unit, a first liquid feeding device, a heat exchanger, a second-order screw unit, a pigment feeding device, a cooler and a buffer tank device. The packaging apparatus includes a filling device and a packaging device.
US11338251B2 Substrate for liquid filter
A substrate for a liquid filter, which includes a polyolefin microporous membrane, the polyolefin microporous membrane having a water permeation efficiency of 0.51 to 1.20 ml/min·cm2, the polyolefin microporous membrane having a bubble point of 0.45 MPa or more and 0.70 MPa or less, the polyolefin microporous membrane having a compressibility of less than 15%.
US11338250B2 Substrate for liquid filter
A substrate for a liquid filter, which includes a polyolefin microporous membrane, the polyolefin microporous membrane having a water permeation efficiency of 0.10 to 0.50 ml/min·cm2, the polyolefin microporous membrane having a bubble point of 0.50 MPa or more and 0.80 MPa or less.
US11338249B2 Anti-haze anti-harmful gas air filter membrane as well as preparation method and application thereof
The disclosure discloses an anti-haze anti-harmful gas air filter membrane as well as a preparation method and application thereof. The air filter membrane comprises a nano fiber membrane made of nano fibers and having a two-dimensional or three-dimensional network structure. The nano fiber membrane can be a high-molecular polymer nano fiber membrane prepared by utilizing an electrostatic spinning process, and can also be doped with an organic or inorganic additive capable of adsorbing and absorbing harmful gases, such as VOCs, NOx, SOx and NH3, in the air and/or a photocatalyst capable of degrading these harmful gases in a photocatalysis manner, or the like. The anti-haze anti-harmful gas air filter membrane disclosed by the disclosure can efficiently filter PM2.5 and PM10 particulate pollutants and the like in the air and simultaneously can efficiently identify and clear multiple harmful gases in the air. The anti-haze anti-harmful gas air filter membrane has a wide application prospect in the field of air purification, for example, can be applied to air purification devices, such as screen windows, gauze masks and filter screens.
US11338247B2 Method of stem-based drilling of ultrathin silicon nitride nanopores and nanopore arrays
The invention concerns methods for preparing a nanoporous silicon nitride membrane comprising (i) ablating portions of at least one side of the membrane with an electron beam to reduce the thickness of the portions to between about 0.5 and 5 nanometers, and (ii) penetrating subportions of the ablated portions of the membrane with an electron beam to form nanopores having internal surfaces which are predominantly silicon rich compared to unablated portions of the membrane.
US11338246B2 Nozzle filter
Devices and methods for the filtration of particulates from a liquid stream are provided. A filter cartridge includes a housing configured to be placed in-line with a stream of liquid and a plurality of hollow fiber filter members disposed within the housing. The hollow fiber filter members are potted at one end of the housing and configured to capture particulates from the stream of liquid via surface energy. The filter cartridge can provide low pressure loss filtering and is capable of being placed within a small space.
US11338243B2 Methods and apparatus to thermally destruct volatile organic compounds
Methods and apparatus to thermally destruct volatile organic compounds are disclosed. An example thermal oxidizer for a furnace includes: an oxidation chamber comprising an inlet configured to receive exhaust gases from a furnace and an outlet configured to output resultant gases; and a plurality of heating elements within the oxidation chamber configured to heat the exhaust gases to oxidize one or more components of the exhaust gases between the inlet and the outlet to result in the resultant gases, the plurality of heating elements comprising resistive heating elements forming coils having respective axes, the plurality of heating elements being oriented within the oxidation chamber such that the axes of the coils are transverse to an exhaust gas flow direction from the inlet to the outlet of the oxidation chamber.
US11338239B2 Coalescing filter media
Filter media, filter elements, and methods for filtering an gas stream are described herein. In some embodiments, the filter media may comprise a fiber web comprising a plurality of fibers and having a particular oil repellency level. For instance, in certain embodiments, the surface chemistry of the fiber web may be tailored to impart a particular surface energy density that matches the surface energy density of the fluid (e.g., an oil, a lubricant, and/or a cooling agent) being removed from the gas stream. In some embodiments, the fiber web may be wrapped around a core. For example, the fiber web may be wrapped around the core such that it forms two or more layers around the core. In some cases, the fiber web may be perforated. In certain embodiments, an gas stream comprising a fluid (e.g., an oil, a lubricant, and/or a cooling agent) may be passed through the fiber web, filter media, and/or filter element such that at least a portion of the fluid coalesces on the fiber web. Fiber webs, filter media, and/or filter elements as described herein may be particularly well-suited for applications that involve filtering gas streams containing oil, lubricants, and/or cooling agents (e.g., gas streams generated by a compressor) though the media may also be used in other applications. Advantageously, the fiber webs, filter media, and/or filter elements described herein may significantly reduce or prevent fouling of the filter caused by oil or other liquids.
US11338234B2 Air filtration media with performing enhancing additives
An air filter that includes a filtration material having at least one surface, an enclosed frame surrounding said filter material but exposing said one surface, said filter material having intermittent geometric shapes of latex on said at least one surface, said latex containing an enhanced additive.
US11338232B2 Efficient non-clogging inertial vortex type particle scrubber
An inertial vortex particle scrubber includes a housing having an inlet guide, twin vortex chambers and an outlet. A particle-laden air stream is accelerated as it passes through the inlet guide into the twin vortex chambers where particles are displaced by centrifugal forces toward a wall of the twin vortex chambers. A relatively particle-free air stream is then discharged from the outlet.
US11338229B2 Intake bypass flow management systems and methods
Filtration systems having a normal filtration mode and an enhanced filtration mode are described. In some arrangements, the filtration system is an air filtration system having a primary air filter element, a pre-cleaner, and a pre-cleaner bypass valve. Based on feedback from an intake air quality sensor the bypass valve is either opened or closed to selectively route intake air through the pre-cleaner during sensed dirty air operating conditions (e.g., heavy dust or moisture concentrations). In other arrangements, the filtration system is a liquid filtration system (e.g., a fuel or oil filtration system) that has a main filter and a secondary filter. The filtration system selectively routes the liquid being filtered through the main filter, the secondary filter, or a combination thereof depending on a detected event or sensed characteristic of the liquid.
US11338228B2 Continuous rotary plate filter and methods of use thereof
The present disclosure provides for a continuous rotary plate filter apparatus and a method of using the apparatus to separate slurries into liquids and solids. The methods and apparatus are useful for the production of fine chemicals and pharmaceuticals, particularly using Integrated Continuous Manufacturing (ICM), but can also be integrated with other manufacturing processes, such as batch and semi-continuous processes.
US11338222B2 Cannabis products modified by removing volatile organic compounds and adding volatile unsaturated hydrocarbons
Purified and modified Cannabis products and methods for producing the same. The purified Cannabis product comprises substantially no volatile organic compounds while retaining Total Potential cannabinoid content. The modified Cannabis product comprises a purified Cannabis product modified by at least one added volatile unsaturated hydrocarbon. The modified Cannabis product is formed by extracting a volatile organic compound from a Cannabis raw material to form a purified Cannabis product, and then adding the at least one volatile unsaturated hydrocarbon to the purified Cannabis product to form the modified Cannabis product and cause an enhanced user experience during combustion and inhalation of the modified Cannabis product.
US11338217B1 Short distillation head with integrated cooling spiral
A distillation apparatus has a cooling spiral surrounding at least a part of a vertical extent of a fraction collector in the disclosed technology. Connecting to and/or extending into an interior space of the fraction collector is an end of a vertically-extending passageway. This passageway is functionally connected at an other end to a lower-end entry portal. An outer cover substantially covers the cooling spiral, fraction collector, and a portion of the vertically-extending passageway, excepting for a top portal, a side exit portal, at least one cooling spiral intake, and at least one cooling spiral outtake.
US11338216B2 Assembly structure
An assembly structure includes a cylindrical part with an end closed on one side. The cylindrical part has three columnar protrusions that protrude from the end to one side and a cylindrical boss portion that is positioned within the cylindrical part such that the three protrusions of another assembly structure are fitted between the boss portion and an inner peripheral surface of the cylindrical part. The inner diameter of the cylindrical part is smaller than the sum of double the outer diameter of the protrusion and the outer diameter of the boss portion. When one protrusion of the other assembly structure is arranged on the outside of the cylindrical part, the two remaining protrusions of the other assembly structure are fitted between the boss portion and the inner peripheral surface of the cylindrical part.
US11338212B2 Park ride with weight proportional water braking
A water ride including vehicles that ride on a track and using water for braking. A run-out section of the track is provided after a drop or down chute section, and the track in the run-out section runs through a pool of water at a depth causing at least a portion of a vehicle riding on the rails to contact a depth of the water to achieve vehicle braking. Significantly, the new water ride is adapted to adjust or set a variable height of the rails in the run-out chute or pool to adjust the depth of water providing water drag on a vehicle traveling through the run-out section based on the vehicle weight. A braking force is applied by the water that is proportional to vehicle weight, and the water ride may be thought of as slowing vehicles with a range of weights at about the same deceleration rate.
US11338210B2 Remote networked services for providing contextual game guidance
Computer-implemented systems and methods for providing contextual game guidance are described herein. An example method includes determining based on contextual information regarding an application an objective of the user; automatically deriving based on the contextual information and the objective contextual guidance to assist the user; generating a user interface having the contextual guidance; and transmitting the user interface to a client device.
US11338207B2 Systems and methods of handling user interaction for obtaining in-game content
When a first giving condition is satisfied, first giving of giving an in-game content selected from a content group including a plurality of in-game contents as selection target contents, to a user, is performed. Furthermore, an option as to whether or not to execute second giving for which an upper limit number of times of further giving is possible in addition to the first giving is set is presented to the user. When execution of the second giving is selected, if an exchange parameter satisfies a second giving condition, the parameter is changed and the second giving is performed. Moreover, the in-game content for which the first giving or the second giving has been performed is excluded from subsequent selection targets.
US11338204B1 Systems and methods for distributing geolocation-specific benefits to unique digital articles based on real-world information
Systems and methods to distribute geolocation-specific benefits to unique digital articles, based on real-world information, are disclosed. Exemplary implementations may execute instances of a game; manage player accounts associated with the players, including a first and a second player account associated with a first and a second player; record player-configurable sensitivity of player-owned unique digital articles to receive distributions of benefits; determine real-world information based on events that have occurred in the real world; determine geolocation information for the first and second player; evaluate whether to distribute and/or adjust the benefits, based on the real-world information and the geolocation information; and provide the (adjusted) distributions of benefits accordingly.
US11338198B2 Programmable hand-held video gaming controller with integrated foot-pedal gaming controller platform
A gaming platform including a programmable hand-held video gaming controller in electrical communication with an integrated foot-pedal gaming controller and/or an integrated mouthpiece gaming controller platform. The programmable hand-held video gaming controller including at least one game function activation area, each of the at least one game function activation areas operating a game function, each of the at least one game function activation areas further including a function control transfer switch. The integrated foot-pedal gaming controller platform including at least one foot pedal configured to control at least one game function when a corresponding function control transfer switch on the programmable hand-held video gaming controller is activated; and the integrated mouthpiece gaming controller platform configured to control at least one game function when a corresponding function control transfer switch on the programmable hand-held video gaming controller is activated.
US11338196B2 Game control method, game control device, and recording medium therefor
The present disclosure relates to a game control technology. An embodiment provides a computer-readable recording medium storing a program for executing a game control, the program being configured to implement: a display control function configured to conduct a control such that a note and an evaluation area indicator that indicates an evaluation area are displayed on a game screen, and to conduct a control such that at least one selected from the note and the evaluation area indicator is output while moving in a preset direction; a receiving function configured to receive an input signal of a user; an evaluation area determining function configured to determine at least one selected from the position of the evaluation area, the shape thereof, and the size thereof on the basis of note characteristic information that is set with regard to each note; and an evaluation function configured to confirm whether or not the note is processed successfully on the basis of the input signal and information regarding proximity of the evaluation area indicator and the note.
US11338194B2 Automatic card shufflers and related methods of automatic jam recovery
Automatic card shufflers may include a card input mechanism for inputting cards into the card shuffler, a card storage device for receiving cards from the card input mechanism and temporarily storing cards within the card shuffler, and a card output mechanism for outputting cards from the card shuffler. The automatic card shufflers may randomly select an internal compartment to be an overflow compartment for inserting cards when a failure of insertion of a card to a selected primary card position occurs.
US11338192B2 Automatic front unit for a ski binding
The invention relates to an automatic front unit for a ski binding, in particular a touring ski binding, wherein the automatic front unit comprises a first retaining means and a second retaining means for retaining a ski boot in the toe region of the ski boot. This automatic front unit has a first retaining configuration, in which the two retaining means are in a retaining position, in which the two retaining means are at a first distance from one another, wherein the two retaining means can cooperate with the ski boot in the retaining position such that the ski boot is retained at the automatic front unit so as to be pivotable about an axis oriented horizontally in a transverse direction of the ski. Furthermore, the automatic front unit has a step-in configuration, in which the two retaining means are in a step-in position, in which the two retaining means are at a second distance from one another, wherein the second distance is greater than the first distance and wherein the ski boot is released from the two retaining means in the step-in position of the two retaining means, wherein the automatic front unit is adjustable from the step-in configuration into the first retaining configuration and back again. The two retaining means, in order to be adjusted from their step-in position into their retaining position and back again, are mounted so as to be movable in translation relative to one another along an adjustment path, wherein a region of the adjustment path that adjoins the retaining position of the two retaining means is oriented substantially horizontally.
US11338191B2 System and user interface for officiating and spectating flag football
Disclosed herein are devices, systems, and methods for officiating, spectating, and scorekeeping for flag football games using one or more wirelessly interconnected electronic devices. In some embodiments, a plurality of graphical user interfaces are provided on a mobile electronic device, the interfaces allowing game officials to create games that are visible to spectators, players, coaches, and statisticians/scorekeepers on a shared geographic map. After spectators, players, coaches, and/or statisticians/scorekeepers join a game, an official inputs information regarding timing and scorekeeping of the game to an interface of a mobile device carried by the official, and the inputted information is broadcasted from the official's device to mobile devices of spectators, players, and coaches, where it is displayed in real-time on graphical user interfaces of the receiving devices. The interfaces may facilitate real-time synchronization of a play-clock and/or go-clock amongst officials, spectators, players, coaches, and/or statisticians/scorekeepers.
US11338190B2 User interface with segmented timeline
A method includes receiving a video input, receiving an indication of a first segment type corresponding to a first workout activity being performed in the video input, and generating a segmented timeline with the processor, the segmented timeline including a plurality of segments, and at least one segment of the plurality of segments corresponding to the first workout activity. The method further includes generating a user interface with the processor, the user interface including the segmented timeline displayed together with at least part of the video input. The method also includes providing the user interface to a plurality of exercise machines via a network.
US11338183B2 Iron-type golf club head
Disclosed herein is an iron-type golf club head comprising a body comprising a heel portion, a sole portion, a toe portion, and a topline portion. The topline portion has a mass per unit length of between 0.09 g/mm and 0.40 g/mm. The golf club head also comprises a strike plate coupled to the body at a front portion of the golf club head and a cavity defined between the topline portion, the sole portion, and the strike plate. The golf club head further comprises a bridge bar at a rear portion of the golf club head. The bridge bar spans the cavity, is spaced apart from the strike plate, and is rigidly fixed to and extends uprightly between the sole portion and the topline portion. The bridge bar has a mass per unit length of between 0.09 g/mm and 0.40 g/mm.
US11338182B2 Golf club heads with stiffening ribs
A hollow golf club head comprising a first component and a second component. The first component comprises a crown return extending rearwardly from a strikeface and forming a portion of a crown; a sole return extending rearwardly from the strikeface and forming a portion of a sole; a sole extension extending rearwardly from the sole return; and a back rail connected to the sole sections. The back rail comprises a top wall, a rear wall, and a lip, which together define a channel extending along the back rail in a heel to toe direction. The second component comprises a heel side wing and a toe side wing that extend from the crown to the sole around a heel end of the club head. The channel is configured to receive a weight portion. The first component comprises a majority of the overall mass of the golf club head.
US11338181B2 Golf club head with molded polymeric body
A golf club head includes a forward section and a body section to define a closed internal volume. The forward section has a strike face, a frame that surrounds the strike face, and a flange extending from the frame. The body section is formed from a molded polymeric material, and includes a forward edge that defines a receiving portion adapted to receive the flange and a weight receiving feature spaced apart from the forward edge. The body section further includes a reinforcing structure protruding into the internal volume and extending between the weight receiving feature and the forward edge. The reinforcing structure is operative to transfer impact loads between the weight receiving feature and the metallic forward section.
US11338180B2 Golf club head with polymeric insert
A golf club head includes a first portion joined to a second portion to at least partially define an interior club head volume. The first portion includes a wall defining an outer boundary of the club head volume, and a support rib extending from the wall to operatively stiffen the first portion. The second portion of the golf club head can engage the support rib, and the support rib can be adhered to the second portion to join the first portion and the second portion.
US11338179B2 Golf club head
A golf club head having a hollow structure is provided. The golf club head includes a face, and a body including at least a crown, a sole, and a hosel chamber. The crown, the sole, and the hosel chamber include laminated layers of a fiber-reinforced resin. The crown includes at least one first rigidity control portion that partially extends in a toe-heel direction. The sole includes at least one second rigidity control portion that extends from a back surface side of the face toward a back end of the body. One of the first rigidity control portion and the second rigidity control portion decreases flexural rigidity in a face-back direction, and the other of the first rigidity control portion and the second rigidity control portion increases flexural rigidity in the face-back direction.
US11338176B2 Dimple patterns for golf balls
The present invention provides a method for arranging dimples on a golf ball surface in which the dimples are arranged in a pattern derived from at least one irregular domain generated from a regular or non-regular polyhedron. The method includes choosing control points of a polyhedron, generating an irregular domain based on those control points, packing the irregular domain with dimples, and tessellating the irregular domain to cover the surface of the golf ball. The control points include the center of a polyhedral face, a vertex of the polyhedron, a midpoint or other point on an edge of the polyhedron and others. The method ensures that the symmetry of the underlying polyhedron is preserved while minimizing or eliminating great circles due to parting lines.
US11338172B2 Treadmill with restraint device
The present invention provides a manual treadmill, the manual treadmill includes a frame having a front support portion and a rear support portion, a running belt disposed about and supported by the front support portion and the rear support portion, and a speed limiting device, wherein the running belt rotates in a first rotating direction or a second rotating direction in response to a directional movement of a user. The speed limiting device includes a one-way bearing, a rotating element and a transmission element, wherein the rotating element is coupled to the front support portion, and the one-way bearing is connected to the rotating element via the transmission element to limit a speed of the running belt in the second rotating direction.
US11338171B2 Exercise apparatus
The present disclosure relates to an exercise apparatus. More particularly, the present disclosure relates to an apparatus operated by hand which comprises a base upon which extend frame supports for the seat unit, resistance unit, crank unit, and guide unit. Embodiments provide for a crank to be mounted to the base and frame and wherein the crank is connected to first and second actuating rods via a coupling. The actuating rods are slidably connected at one end via a guide pivotally mounted to the frame and have a free end for a user to grip.
US11338170B2 Exercise bar
A portable exercise device for use in resistance training programs is provided, which can comprise: a hollow structure; multiple resistance bands, each shorter than the hollow structure; multiple anchor members for securing the resistance bands to the hollow structure; multiple attachable and detachable handles; wherein one end of each resistance band is coupled to an anchor; wherein an opposing end of each resistance band is operably configured for attachment to a handle; such that each resistance band is contained completely within the hollow structure during rest and is capable of extending outside the hollow structure during use when attached to a handle. Such devices can be used by attaching a handle to a resistance band at each end of the hollow bar, gripping the bar with hands, placing feet in the handles, and moving the bar away from the feet to create resistance in the bands thereby exercising the user's body. Such devices can also be used by attaching a handle to the resistance band at each end of the hollow bar, whereby the handle is three-sided and each side serves a different adapted function; for example, one side may be configured for gripping by a user's hand, one side may be configured for engaging by the user's foot, and one side may be configured to anchor to an anchoring structure.
US11338169B2 Strength training apparatus
Embodiments of a strength training apparatus and related methods are provided. In one embodiment, a strength training apparatus may include a tower, a first arm and a second arm each pivotally coupled with the tower and each being configured to be selectively positionable independent of each other at multiple angles relative to each other, a first pulley coupled to an end of the first arm, a first cable extending through the first arm and the first pulley, a second pulley coupled to an end of the second arm, a second cable extending through the second arm and the second pulley, a magnetic mechanism coupled to the first cable and the second cable and configured to provide multiple levels of resistance to a user pulling on the first cable and/or the second cable, and a control panel located on the tower.
US11338167B2 Exercise device and method of use
An exercise device that simultaneously incorporates both balance and resistance training comprises a base including a rear and a front portion; a balancer disposed in the base proximal to the front portion of the base and configured to both support a user thereon and move with weight shifting by the user thereon; one or more lines retractably disposed in the front portion of the base; a resistance mechanism disposed in the base and operably associated with the one or more lines, wherein both balance and resistance training are provided by the balancer and the resistance mechanism when a user attempts to balance the user's weight on the balancer while pulling on the one or more lines.
US11338166B2 Physical stretching apparatus
A physical stretching apparatus having: an anchor strap, wherein the anchor strap is configured to be operable for attaching the apparatus to any stationary object; an anchor joint, the anchor joint is configured to attach the anchor strap and a rope implement; an elastic looped strap configured to secure the apparatus to various points on a user; an attachment contrivance, wherein the attachment contrivance is configured to be operable for attaching the elastic looped strap to the rope implement; a rope lock that is configured to permit the rope implement to pass in one direction when pulled and restricts the rope implement from passing in an opposite or reverse direction; a release mechanism that disables this restriction; and a sliding restrainer, wherein the sliding restrainer is configured to be operable for adjusting a size of the looped strap.
US11338165B2 Multiple movement exercise device
An exercise device for allowing multiple exercise movements is provided. The device includes a substantially cube-shaped frame, and a unit for doing exercise movements on at least one side of the frame.
US11338164B2 Flexible sporting apparatus description
A flexible sporting apparatus includes an elongated and flexible body (2), which can be gripped, connected to the body of a person or connected to another identical or different apparatus, wherein the body (2) includes at least one flexible connection element (10, 11, 12) extending between a first end (3) and a second end (4) of the body (2), at least for a part of its length, a plurality of masses (20, 21, 22), distributed between the first end (3) and the second end (4) of the body (2), joined integrally to the at least one connection element (10, 11, 12) so that their position, in the direction of the length of the body, is maintained substantially unchanged when the apparatus is moved or bent; and optionally a containment element (30) that surrounds the at least on connection element (10, 11, 12) and the masses (20, 21, 22).
US11338161B2 Fire system rule generation
Methods, devices, and systems for fire system rule generation are described herein. In some examples, one or more embodiments include a memory, and a processor to execute instructions stored in the memory to receive a rule input condition and a rule output condition for a fire control system of a facility, generate a fire system rule for the facility based on the rule input condition and the rule output condition, and transmit the fire system rule to a fire control panel of the fire control system of the facility.
US11338160B2 Focused stream, aerated foam projecting nozzle including fixed wand system and method as well as possibly portable center pointing nozzle
The invention includes components and methodology for fixed and semi-fixed systems for extinguishing fire in large industrial flammable liquid storage tanks, including aerated foam projecting nozzles discharging substantially focused streams together with aeration chambers and risers.
US11338159B2 Fire detection in thermal images
One or more thermal images containing pixel-by-pixel radiation intensity data in two or more wavelength bands can be processed to accurately determine the location of fire within the image(s), regardless of the radiation-scattering effects of smoke. First, all pixels having radiation intensities above a fire threshold in the longer-wavelength band are classified as being aflame. Second, a threshold curve defining a fire threshold in the shorter-wavelength band is applied to the pixels, and those having radiation intensities above the fire threshold in the shorter-wavelength band are classified as being aflame. Third, at least the second group of pixels above is tested to see if each pixel classified as being aflame is part of a group of adjoining pixels which were all classified as being aflame, and if so, each such pixel is reclassified as not being aflame unless it also falls within the first group of pixels above.
US11338158B2 System and a method for delivering breathing gas to passengers on-board an aircraft
A system for delivering breathing gas to passengers on-board an aircraft, including: a source of breathing gas, at least one face mask for passengers, a reservoir associated with each face mask, a delivery valve for each face mask, the delivery valve being disposed between the source of breathing gas and the reservoir, the reservoir being disposed between the delivery valve and the face mask, a sensor associated with each reservoir and configured to sense a filling of the reservoir, and a controller configured to control the delivery valve in a continuous supply mode to provide a continuous flow of breathing gas to the reservoir and to interrupt the continuous flow of breathing gas when the filing sensed by the sensor is a filling threshold.
US11338153B2 Phototherapeutic apparatus and protocol setting method for phototherapeutic apparatus
Provided is a phototherapeutic apparatus including: a probe that is held and operated by a user and provided with a photo-irradiation unit that performs irradiation with light beams; and a body provided with a control unit that controls the light beams. The body is provided with a read unit that reads a treatment protocol registered in an IC card (mobile memory medium), and a monitor (operation indication unit) that indicates a region to be irradiated with the light beams to the user, the region being set in the treatment protocol, and the control unit causes the monitor to indicate the region to be irradiated and causes the photo-irradiation unit to perform the irradiation with the light beams at a set value set in the treatment protocol. It is possible to perform the irradiation with the light beams in accordance with the treatment protocol and safely use the phototherapeutic apparatus.
US11338148B2 External power devices and systems
Described herein are devices, systems, and methods for wireless power transfer utilizing a midfield source and implant. In one variation, a midfield source may be realized by a patterned metal plate composed of one of more subwavelength structures. These midfield sources may manipulate evanescent fields outside a material (e.g., tissue) to excite and control propagating fields inside the material (e.g., tissue) and thereby generate spatially confined and adaptive energy transport in the material (e.g., tissue). The energy may be received by an implanted device, which may be configured for one or more functions such as stimulation, sensing, or drug delivery.
US11338147B2 Shielding device for signal transmission coil
Systems and apparatuses are used to transmit data between external and internal portions of auditory prostheses or other medical devices. The external portion of the auditory prosthesis includes a magnet and an implanted coil that provides stimulation to the device recipient. A shaped shield material can be placed between the external coil and the sound processing hardware to improve efficiency and effectiveness between the external coil and implanted coil. Adverse effects on tuning frequencies can be reduced by disposing the shield material away from the magnet.
US11338144B2 Current sensing multiple output current stimulators
A multiple output current stimulator circuit with fast turn on time is described. At least one pair of input side and output side transistors is arranged in a current mirror connected to a supply transistor by cascode coupling. The output side transistor supplies stimulation current to an electrode in contact with tissue. An operational amplifier connected to a reference voltage and to the output side transistor drives the supply transistor to maintain the voltage at the output side transistor equal to the reference voltage. The at least one pair of transistors includes multiple pairs of transistors whose output side transistors drive respective electrodes with stimulation currents. The stimulator determines the initiation and duration of stimulation current pulses supplied to each electrode. At circuit activation, large currents are generated which discharge capacitances in the output side transistors causing rapid output side transistor turn on.
US11338142B2 System and method for treating obstructive sleep apnea
One aspect of the present disclosure relates to a system for treating obstructive sleep apnea in a subject. The system can include a power source and a neuromuscular stimulator in electrical communications with the power source. The neuromuscular stimulator can include a controller and at least one electrode. The controller can be configured to receive certain power and stimulation parameters associated with a therapy signal from the power source. The at least one electrode can be configured to deliver the therapy signal to a target tissue associated with control of a posterior base of the tongue of the subject.
US11338140B2 Monitoring of neuromodulation using biomarkers
Provided herein are methods, devices, compositions, and kits for monitoring neuromodulation efficacy based on changes in the level or activity of one or more target biomarkers. One aspect includes a comparison of baseline and post-modulation levels of one or more biomarkers in bodily fluid that have each been collected from a human subject at a relevant time, and that may be used to assess the neuromodulation efficacy. The post-neuromodulation levels for the one or more biomarkers may be collected from the human subject within about 5 minutes to about 14 days post-neuromodulation.
US11338139B2 System and methods for controlled electrical modulation for vision therapy
Illustrative methods and devices for providing stimulus to the eye to treat vision disorders. Systems and methods for feedback relating to the stimulus itself as well as the effect of such stimulus on the patient are provided. Various examples may include therapies for vision disorders that can progress to blindness, such as macular degeneration or other diseases and disease processes.
US11338135B2 Medical devices for cancer therapy with electric field shaping elements
Embodiments herein relate to medical device systems including electric field shaping elements for use in treating cancerous tumors within a bodily tissue. In an embodiment, a medical device system for treating a cancerous tumor is described. The medical device system can include one or more electric field generating electrodes and an electric field shaping element configured to be implanted along with the one or more electric field generating electrodes. The electric field shaping element can be made from a material that alters the spatial area of tissue exposed to the electric field. Other embodiments are also included herein.
US11338131B1 Guiding implantation of an energy delivery component in a body
A system for guiding implantation of an energy delivery component of a cardiac pacing device at a fixation location within a heart of a patient is provided. During a procedure to implant an energy pulse delivery component, the system receives a patient cardiogram collected during pacing of the energy pulse delivery component while the energy pulse delivery component is positioned at a current location within the heart. The system then determines based on the patient cardiogram the current location of the energy pulse delivery component. The system then outputs an indication of the current location to guide affixing of the energy pulse delivery component at the intended fixation location. This process is repeated until the energy pulse delivery component is at the fixation location. The system also evaluates the effectiveness of pacing at intermediate location to optimize the final location based upon simulated electro-mechanics of the system in near-real time.
US11338127B2 Stimulation modes to adapt customized stimulation parameters for use in a spinal cord stimulation system
A method is disclosed for programming a patient's stimulator device using an external device. The method provides a Graphical User Interface (GUI) on the external device that allows the patient to select from a plurality of displayed stimulation modes to program stimulation provided by one or more electrodes of the stimulator device. The external device stores a model derived for the patient, which model comprises information indicative of a plurality of frequency/pulse width/amplitude coordinates predicted to provide optimal stimulation for the patient. Each stimulation mode corresponds with a subset of coordinates defined in accordance with the plurality of coordinates in the model. Selection of one of the stimulation modes limits programming the stimulator device with coordinates that are within the corresponding subset of coordinates.
US11338123B2 Blood pump devices and associated systems and methods
The present technology provides a blood pump device and associated systems and methods of use thereof to assist blood circulation in a patient. The blood pump device includes a flexible member disposed within a housing. Movement of the flexible member in the housing varies the volume of chambers within the housing and effectuates pumping of blood to and from a vessel in fluid connection with a chamber of the blood pump device.
US11338120B2 Methods and devices for treating parasympathetic bias mediated conditions
Methods for treating a subject for a parasympathetic bias mediated condition are provided. Aspects of the methods include modulating at least a portion of the subject's autonomic nervous system to increase the sympathetic/parasympathetic activity ratio in a manner effective to treat the subject for the parasympathetic bias mediated condition. In some instances, the subject is known to have parasympathetic bias. Also provided are devices that find use in practicing various embodiments of the methods.
US11338119B2 Implantable drug delivery devices for localized drug delivery
Provided herein are drug implants comprising a therapeutically active agent for the treatment of disease in a subject. In some cases, the drug implant may comprise a polymer matrix and a therapeutically active agent disposed therein. Additionally provided are methods for manufacturing the drug implants and methods of treating diseases with the implants. In some cases, the drug implant may comprise bicalutamide, e.g., for use in the treatment of prostate cancer.
US11338117B2 Implantable dual pathway therapeutic agent delivery port
A treatment system includes a dual lumen catheter system. The first lumen is open to systemic circulation. The second lumen is open to a target delivery location. In an embodiment, a pressure-control element is provided that includes an expanded configuration adapted to constrain delivery through the second lumen to the target delivery location. Methods for treating tissues and organs via vascular pathways are provided.
US11338114B2 Magnetic catheter system and methods
A catheter system may include a needle assembly coupled to a catheter adapter. The needle assembly may include a housing, an introducer needle, a distal opening, a first magnet, and a second magnet. In response to proximal withdrawal of the introducer needle, the first magnet may move towards the second magnet, which may block the distal opening and/or prevent blood from leaking out the distal opening.
US11338109B2 Hydrophilic medical products and hydration mediums for hydrating the same
Hydration mediums, assemblies containing hydration mediums and methods of making the same are disclosed. The hydration mediums are intended for hydrating or wetting a medical device such as a catheter and comprise a hydration foam. Furthermore, methods and products involving hydrophilic substances are disclosed e.g. involving mucilage, deep eutectic liquids, antifreeze substances or cryoprotectants, oil or a hydration medium together with water, surfactant, polyol and stabilizer.
US11338106B2 Hearing assistance devices with motion sickness prevention and mitigation features
Embodiments herein relate to devices and related systems and methods for motion sickness prevention and mitigation. In an embodiment, a method of preventing or mitigating motion sickness in a subject is included, the method tracking motion of the subject using a first motion sensor; estimating a vestibular system input based on tracked motion of the subject; tracking head position of the subject using the first motion sensor; estimating a visual system input based on tracked head position of the subject; estimating consistency between the vestibular system input and the visual system input; and initiating a responsive measure if the estimated consistency crosses a threshold value. Other embodiments are also included herein.
US11338105B2 Respiratory humidification device
A respiratory humidification device includes: a casing; a separator wall to divide an interior space into filling and humidification chambers, wherein a bottom edge of the separator wall leaves a space between it and the casing bottom to define a passage allowing water to flow atop the casing bottom between the chambers, and enabling the water level to rise enough to block the passage to prevent respiratory gas from passing therethrough; a valve and float within the filling chamber to control water flow into the filling chamber to prevent the water level from rising higher than a threshold; and wherein an outer wall of the casing and the separator wall cooperate with the water surface within the humidification chamber to define an elongate tube-like pathway through which respiratory gas proceeds along a path extending generally parallel to the water surface within the humidification chamber to be humidified.
US11338101B2 Oxygen supply device and method for controlling same
An oxygen supply device supplying a user with an oxygen gas for inhalation acquires information of the user on percutaneous arterial oxygen saturation (SpO2) using a sensor unit, and calculates, from SpO2, the first moving average value and the second moving average value calculated over a time span longer than the first moving average in a control unit. The control unit calculates a Dip frequency during predetermined time from the SpO2 information, and when the calculated frequency is equal to or larger than the first threshold, the control unit switches the control from the control based on the first moving average value of SpO2 to the control based on the second moving average value.
US11338100B2 Blowing device and fluid control device
An inner peripheral surface of an upper plate of a first case has a first inclined surface that faces an outer peripheral surface of a seal holding member of a motor in a radial direction of a rotary shaft. An inner peripheral surface of a seal fixing member has a second inclined surface that also faces the outer peripheral surface of the seal holding member in the radial direction. The outer peripheral surface has third and fourth inclined surfaces along an axial direction of the rotary shaft. An outside diameter on sides of the third and fourth inclined surfaces that are far from each other is greater than an outside diameter on sides of the third and fourth inclined surfaces that are near each other. A sealing member is installed in an annular space that is surrounded by the first, second, third, and fourth inclined surfaces.
US11338096B2 Medicament injection device
The present disclosure relates to a medicament injection device (1) comprising a housing (3) arranged to receive a medicament container (11a), a needle cover (9) movable relative to the housing (3), from a retracted position, in which it engages the housing (3) and enables medicament delivery, to an extended position, a plunger rod (7), and a plunger driver (5) movable relative to the housing (3) from all initial position to a final position, and arranged to actuate the plunger rod (7), wherein the plunger rod (7) has a first guide arrangement and the housing (3) has a second guide arrangement, the first guide arrangement (7d) and the second guide arrangement being arranged to cooperate to guide movement of the plunger rod (7) relative to the housing (3), wherein the first guide arrangement and the second guide arrangement in a first stage provide a linear motion path for the plunger rod (7), enabling the plunger rod (7) to initially move in the axial direction and in a second stage provide a rotation motion path for the plunger rod (7), enabling the plunger rod (7) to rotate relative to the housing (3) to release the plunger rod (7) from the plunger driver (5), whereby the plunger driver (5) attains a released state enabling movement of the plunger driver (5) to its final position, wherein in the released state the plunger driver (5) is arranged to release the needle cover (9) from the housing (3) and to actuate the needle cover (9) to its extended position.
US11338090B2 Anti-rotation cartridge pin
A system is disclosed for inserting a pharmaceutical cartridge into a delivery device. Optionally the cartridge is inserted in an arbitrary orientation. Optionally, the system reorients the cartridge to a locked orientation. For example, a driver applies a torque to the cartridge to cause the reorienting. For example, said torque rotates the cartridge around an axis thereof until the cartridge reaches the locked orientation. Optionally, when the cartridge reaches the locked orientation an interference element on the cartridge interlocks with a complementary interference element on the delivery device to lock the cartridge in the locked orientation. Optionally when the cartridge is locked in the second orientation, the torque causes discharge the pharmaceutical.
US11338088B2 Venting safety closure
A closure for use with a specimen collection container is disclosed. The closure includes a base portion having a first end adapted for engagement with an open end of the specimen collection container, and a second end adapted for receiving a portion of a syringe assembly therein. The closure also includes a luer fitting connected to the base portion and having at least one channel for venting an interior of the specimen collection container to atmosphere during introduction of a fluid specimen from the syringe assembly into the specimen collection container. The closure further includes a shielding portion connected to the base portion and adapted to transition from an open position in which fluid communication is established between the first end and the second end through the luer fitting, to a closed position in which the luer fitting is fully shielded by the shielding portion.
US11338081B2 Fluid mixing device
A fluid mixing device includes inlet ports in fluid communication with respective source containers, an inlet check valve, a mixing container in fluid communication with the inlet check valve, a discharge port in fluid communication with a target container, and a discharge check valve in fluid communication with the mixing container and the discharge port. Responsive to a negative pressure at the mixing container, fluid is drawn from the respective source containers through the inlet ports and through the inlet check valve and into the mixing container, while the discharge check valve precludes drawing of fluid from the target container. Responsive to a positive pressure at the mixing container, fluid is expelled from the mixing container through the discharge check valve and into the target container, while the inlet check valve precludes discharge of fluid from the mixing container to the inlet ports and the source containers.
US11338077B2 Adjustable liposuction cannula
A device for removing fat from a body can include a pair of nested hollow members that each has at least one opening and an adjustment means for adjusting the orientation of the nested hollow members from a first configuration to a second configuration to change an amount of overlap between openings in the nested hollow members. The nested members can be deformable to change the shape of the openings.
US11338069B2 Fluorescent and/or NIR coatings for medical objects, object recovery systems and methods
A composition for coating a medical device and a coated medical device are provided. The composition includes a polymeric matrix having non-toxic quantum dots or a fluorophore or both. The polymeric matrix contains the quantum dots or fluorophore and binds as a coating to the medical device. Coated medical devices can be readily identified within or outside of a body and in open or laparoscopically surgeries, greatly reducing or eliminating the risk of a retained foreign object.
US11338068B2 Two-part implantable therapy delivery device
An implantable therapy delivery device that includes a porous pouch and a cell encapsulation device configured to fit inside the porous pouch. The porous pouch may include a bio-absorbable material and/or a vascularization promotor, and the porous pouch may be packaged separately from the cell encapsulation device.
US11338064B2 Biological valve for venous insufficiency
A bioprosthetic valve for repairing a deep venous insufficiency in a subject includes a single leaflet from a xenogeneic heart valve attached at natural margins of attachment to a patch of valve wall tissue. The patch may extend axially above and below the leaflet and circumferentially on either side of the leaflet to provide a region for attaching the patch to a fenestration in a host vein. A bioprosthetic valve may be manufactured by excising a portion of a xenogeneic heart valve including a single leaflet and contiguous wall tissue, and may further comprise shaving off excess leaflet tissue from adjacent leaflets. A method of replacing a malfunctioning venous valve in a subject includes providing a bioprosthetic valve as described above and inserting it to the host vein.
US11338063B2 Placental tissue grafts modified with a cross-linking agent and methods of making and using the same
Described herein are tissue grafts derived from the placenta that possess good adhesion to biological tissues and are useful in wound healing applications. In one aspect, the tissue graft includes (1) two or more layers of amnion, wherein at least one layer of amnion is cross-linked, (2) two or more layers of chorion, wherein at least one layer of chorion is cross-linked, or (3) one or more layers of amnion and chorion, wherein at least one layer of amnion and/or chorion is cross-linked. In another aspect, the grafts are composed of amnion and chorion cross-linked with one another. In a further aspect, the grafts have one or more layers sandwiched between the amnion and chorion membranes. The amnion and/or the chorion are treated with a cross-linking agent prior to the formation of the graft. The presence of the cross-linking agent present on the graft also enhances adhesion to the biological tissue of interest. Also described herein are methods for making and using the tissue grafts.
US11338062B2 Fiber-hydrogel composite surgical meshes for tissue repair
The presently disclosed composition and methods are provided for a hydrogel or nanofiber-hydrogel composite integrated with a surgical scaffold or mesh. A surgical scaffold device comprised of laminar composite is disclosed for the purpose of reducing foreign body response, managing tissue-materials interface, and improving the integration of the surgical mesh with the surrounding tissue of a subject.
US11338060B2 Methods for development and use of minimally polarized function cell micro-aggregate units in tissue applications using LGR4, LGR5 and LGR6 expressing epithelial stem cells
Provided herein are constructs of micro-aggregate multicellular, minimally polarized grafts containing Leucine-rich repeat-containing G-protein coupled Receptor (LGR) expressing cells for wound therapy applications, tissue engineering, cell therapy applications, regenerative medicine applications, medical/therapeutic applications, tissue healing applications, immune therapy applications, and tissue transplant therapy applications which preferably are associated with a delivery vector/substrate/support/scaffold for direct application.
US11338059B2 Method of corneal and scleral inlay crosslinking and preservation
A method of corneal and scleral inlay crosslinking and preservation is disclosed herein. The method includes cross-linking at least a portion of a donor cornea or a donor sclera so as to kill cellular elements in the portion of the donor cornea or the donor sclera, and make the portion of the donor cornea or the donor sclera less antigenic to a body portion of a recipient patient in which the portion of the donor cornea or the donor sclera is to be implanted; and storing the cross-linked donor cornea or the donor sclera for a long period of time prior to implanting the portion of the donor cornea or the donor sclera into the body portion of the recipient patient.
US11338058B2 Injectable peripheral nerve specific hydrogel
The present invention relates to a peripheral nerve-specific hydrogel material, which is deliverable in a minimally invasive fashion, sustains the growth of neurons, and speeds recovery following surgical reconstruction.
US11338054B2 Phosphocalcic cement composition comprising blood
A method for promoting spine fusion inside intersomatic cages, comprising placing a fusion cage between two vertebral bodies, and injecting a bone cement paste inside said fusion cage, said bone cement paste containing a powder component comprising α-tricalcium phosphate (α-TCP) particles having an average size greater than or equal to 9 μm, and a liquid component comprising blood.
US11338053B2 Antimicrobial systems for personal spaces
An air purification system, includes a UVC light source arranged within an internal space of a purification chamber and adapted to irradiate the internal space with UVC, an airflow system arranged to introduce environmental air from outside of the air purification system into the internal space of the purification chamber and expel purified air from the purification chamber back outside of the air purification system, and a light blocking system arranged to block a substantial amount of the irradiated UVC from emitting outside of the air purification system, the light blocking system comprising a high-air-flow open structure mounted in the airflow system of the purification chamber, wherein the open structure comprises a front surface, rear surface and a thickness, wherein the front and rear surfaces have a plurality of open areas connected through the thickness, and wherein at least one of the plurality of open areas is of a size with respect to the thickness to block light from traversing the thickness when an angle of incidence is less than approximately 10 degrees.
US11338051B2 Closure mechanisms and seal integrity indicators for sterilization containers
Closure mechanisms for closing and sealing sterilization containers and indicators for indicating the seal integrity sterilization containers are provided. For example, a container closure mechanism may be configured to distribute a closure force along a gasket to seal a container lid to a container body. Further, a seal indicator may visibly indicate at the container exterior whether the container is sufficiently sealed to prevent an ingress of contaminants into the container. If the container is sufficiently sealed, the seal indicator is a first state, and if the sterilization container is not sufficiently sealed, the seal indicator is in a second state. Thus, the seal indicator undergoes a state change when the sterilization container transitions from unsealed to sealed or from sealed to unsealed, such that a user can ascertain whether the container is properly sealed to maintain sterility or whether the seal and sterility of the container have been compromised.
US11338047B2 Method for disinfecting a water system of an aircraft
A method for disinfecting a water system of an aircraft includes letting-in of hot water at an inlet of the water system by a first ground service unit; flushing the hot water from the inlet, through water pipes of the water system, to an outlet of the water system; and letting-out of the hot water at the outlet, by the first ground service unit or a second ground service unit; the hot water being flushed into the inlet and out of the outlet over a predefined disinfection period; and the hot water being provided at the inlet via a continuous-flow heater of the first ground service unit.
US11338046B2 Adenoassociated virus vectors for the treatment of mucopolysaccharidoses
The present invention provides new adeno-associated virus-derived vectors and pharmaceutical compositions containing the same for the treatment of lysosomal storage disorders and specially, for the treatment of mucopolysaccharidoses Type IIID.
US11338045B2 Adeno-associated virus vector delivery of a fragment of micro-dystrophin to treat muscular dystrophy
The invention provides gene therapy vectors, such as adeno-associated vims (AAV) vectors, expressing a functional fragment of the miniaturized human micro-dystrophin gene and method of using these vectors to express the fragment of micro-dystrophin in skeletal muscles including diaphragm and cardiac muscle and to protect muscle fibers from injury, increase muscle strength and reduce and/or prevent fibrosis in subjects suffering from muscular dystrophy.
US11338043B2 Antibody-conjugates with improved therapeutic index for targeting HER2 tumours and method for improving therapeutic index of antibody-conjugates
The present invention concerns novel and improved antibody-conjugates for targeting HER2. The inventors found N that when antibody-conjugates were prepared using a specific mode of conjugation, they exhibit an improved therapeutic index. The mode of conjugation comprises a first step (i) of contacting a glycoprotein comprising 1-4 core N-acetylglucosamine moieties with a compound of the formula S(F1)x-P in the presence of a catalyst, wherein S(F1)x is a sugar derivative comprising x functional groups F1 capable of reacting with a functional group Q1, x is 1 or 2 and P is a nucleoside mono- or diphosphate, and wherein the catalyst is capable of transferring the S(F1)x moiety to the core-GlcNAc moiety, to obtain a modified antibody; and a second step (ii) of reacting the modified antibody with a linker-conjugate comprising a functional group Q1 capable of reacting with functional group F1 and a target molecule D connected to Q1 via a linker L2 to obtain the antibody-conjugate wherein linker L comprises S—Z3-L2 and wherein Z3 is a connecting group resulting from the reaction between Q1 and F1. The invention also relates to a use for improving the therapeutic index of an antibody-conjugate and to a method for targeting HER2-expressing cells.
US11338039B2 Abuse-proof solid pharmaceutical composition
The present invention relates to an abuse-proof solid pharmaceutical composition comprising an active ingredient with potential for abuse, silica in an amount of from 10 mg to 1000 mg, guar flour in an amount of from 100 mg to 300 mg, and a water soluble diluent in an amount of from 500 mg to 5000 mg.
US11338037B1 Ultrastable antibody ionic liquids
A method for creating a stable protein/antibody ionic liquid, comprising: (a) cationizing aqueous proteins/antibodies by addition of an excess of a positively-charged crosslinker in the presence of a coupling reagent; (b) purifying the cationized proteins/antibodies; (c) titrating the cationized proteins/antibodies with a corresponding biologically-compatible counter anionic polymer to create at least one protein/antibody cation/anion pair in aqueous solution until the cation/anion pair solution becomes negative by zeta potential measurement; (d) repeatedly dialyzing the protein/antibody cation/anion pair in water to remove excess anionic polymer using at least one molecular weight cutoff 7000 dialysis membrane; (e) lyophilizing the protein/antibody cation/anion pair to remove most of the water, forming a lyophilized solid; and (f) heating the lyophilized solid until a protein/antibody ionic liquid is generated. The antibody may be any desired antibody, and the anion may be any biologically-compatible anion.
US11338036B2 Methods and compositions for the treatment and/or prevention of type 1 diabetes
The disclosure relates generally to methods and compositions of treating or preventing diabetes mellitus by administering to a subject a composition comprising an amount of stem and/or progenitor cells and at least one antigen-specific therapy.
US11338032B2 Methods of preparing anti-human papillomavirus antigen T cells
Disclosed are methods of preparing an isolated population of human papillomavirus (HPV)-specific T cells comprise dividing an HPV-positive tumor sample into multiple fragments; separately culturing the multiple fragments; obtaining T cells from the cultured multiple fragments; testing the T cells for specific autologous HPV-positive tumor recognition; selecting the T cells that exhibit specific autologous HPV-positive tumor recognition; and expanding the number of selected T cells to produce a population of HPV-specific T cells for adoptive cell therapy. Related methods of treating or preventing cancer using the T cells are also disclosed.
US11338031B2 Vaccine against RSV
The present invention relates to novel nucleic acid molecules encoding a pre-fusion RSV F protein or immunologically active part thereof, wherein the pre-fusion RSV F protein comprises the amino acid sequence of SEQ ID NO: 1 or 2. The invention further relates to the use of the nucleic acid molecules, or vectors comprising said nucleic acid molecules, as a vaccine against respiratory syncytial virus (RSV).
US11338027B2 Fusion comprising a cell penetrating peptide, a multi epitope and a TLR peptide agonist for treatment of cancer
The present invention provides a complex for use in the prevention and/or treatment of cancer, the complex comprising a) a cell penetrating peptide, b) at least one antigen or antigenic epitope, and c) at least one TLR peptide agonist, wherein the components a)-c) are covalently linked. In particular, compositions for use in the prevention and/or treatment of cancer, such as a pharmaceutical compositions and vaccines are provided.
US11338025B2 Vaccine therapy for treatment of endometrial and ovarian cancer
The present invention provides methods of preventing or reducing the risk of recurrence of endometrial and ovarian cancers which express low levels of folate binding protein (FBP) by administration of a vaccine containing an E39 peptide.
US11338023B2 Compositions and methods for modulating and/or stimulating immune responses in human and/or animal
There is provided a composition including parietal polysaccharides from at least one Candida species and parietal polysaccharides from at least one different yeast species. The composition can be used in modulating and/or stimulating immune responses in animal or human.
US11338013B2 Combination therapy for C3 inhibition
In some aspects, the present invention provides certain combination therapies comprising compstatin analogs.
US11338010B2 Systems, methods, and kits for diagnostics and treatment of viral respiratory infection
Systems, methods, and kits for treating, preventing, and diagnosing viral infection using an androgen mediated pathway are described. Additionally, methods and kits for guiding treatment of viral respiratory disease are described by a method for testing for polymorphisms in the androgen receptor gene. Further, systems and methods for treatment of viral respiratory disease with various anti-androgens is detailed. Finally, systems, methods, and kits for treating, preventing, and diagnosing SARS-CoV-2 (COVID-19) are presented.
US11338008B2 Pharmaceutical composition comprising thrombolytic peptide-tetrahydroisoquinoline conjugate
The present invention provides a pharmaceutical composition comprising a binary conjugate, DC009, which is a conjugate of a thrombolytic peptide (Pro-Ala-Lys) and a tetrahydroisoquinoline compound having two C1-4 alkyl groups via a lysine linking arm, and a pharmaceutical acceptable carrier. The composition has a pH less than 6.5, preferably has a pH about pH 2-5.5 The composition may comprise a pharmaceutical acceptable excipient such as mannitol, sorbitol, sucrose, lactose, or trehalose.
US11338007B2 Combination formulation of three antiviral compounds
Disclosed are pharmaceutical compositions comprising three antiviral compounds. In particular, the pharmaceutical compositions comprise an effective amount of velpatasvir, an effective amount of sofosbuvir, and an effective amount of voxilaprevir. Also disclosed are methods of use for the pharmaceutical composition.
US11338004B2 Composition for preventing or treating cranial nerve disease comprising fomes fomentarius extract, fraction thereof, or compound isolated therefrom as active ingredient
The present disclosure relates to a pharmaceutical composition for preventing or treating a cranial nerve disease, comprising a Fomes fomentarius extract, a fraction thereof, or a compound isolated therefrom as an active ingredient. According to the present disclosure, the Fomes fomentarius extract is included as an active ingredient so that there are significant effects of inhibiting the production or expression of inflammatory cytokines and improving the activity of glucose metabolism in the brain to prevent or treat cranial nerve diseases, of lowering side effects on the human body as a natural product, and of being easily prepared and ingested.
US11338000B2 Use of Butyribacter intestini in preventing and/or treating inflammation-related diseases
Provided is a use of Butyribacter intestini in preventing and/or treating inflammation-related diseases. Specifically, in the present disclosure, it was firstly discovered that Butyribacter intestini has the function of preventing and/or treating inflammation-related diseases (for example, inflammatory bowel disease, such as ulcerative colitis, gastritis, and common enteritis; and rheumatoid arthritis).
US11337999B2 Method for producing marine algae-derived agarotriose, and use thereof as prebiotic
The present invention relates to a method for producing marine algae-derived agarotriose, and a use thereof as a prebiotic. More specifically, the present invention investigates the characteristics of agarotriose as a prebiotic which is selectively metabolized by probiotic microorganisms, thereby enabling agarotriose to be used as an anti-cancer or anti-inflammatory agent in the fields of food and pharmaceuticals, and enabling agarotriose to be obtained at high yield through efficient purification with minimal loss after enzymatic hydrolysis of a red algae-derived polysaccharide without pre-treatment.
US11337998B2 Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
The present invention provides improved and/or shortened methods for expanding TILs and producing therapeutic populations of TILs, including novel methods for expanding TIL populations in a closed system that lead to improved efficacy, improved phenotype, and increased metabolic health of the TILs in a shorter time period, while allowing for reduced microbial contamination as well as decreased costs. Such TILs find use in therapeutic treatment regimens.
US11337995B2 Peripheral neuropathy composition and related methods
A analgesic composition for topical application is provided that includes magnesium sulfate and a source of vitamin B12 in an amount effective for providing pain relief associated with peripheral neuropathy. The composition has a viscosity effective for allowing topical application of the composition to an afflicted area where the magnesium sulfate and vitamin B12 is absorbed through the dermis to the subcutaneous to provide pain relief relating to symptoms of peripheral neuropathy. The composition provides the novel benefits of being portable, easily dispensed, and provides a higher concentration of applied magnesium sulfate and vitamin B12 than the traditional dispensing method of Epsom Salt soaking solutions.
US11337994B2 In situ gelling compositions for the treatment or prevention of inflammation and tissue damage
Described herein are in situ gelling compositions. The compositions include an anti-inflammatory polysaccharide and a gelling polymer, wherein the composition is a liquid prior to administration to a subject but converts to a gel upon administration to the subject. The compositions described herein have numerous applications with respect to the local treatment (reduction or prevention) of inflammation and/or tissue damage.
US11337993B2 Compositions and methods for stimulating hair growth
Methods and compositions for stimulating hair growth are disclosed. Compositions for stimulating hair growth include two or more of hyaluronic acid, osteopontin, and another CD44 binding ligand. Methods for stimulating hair growth include administering such composition into the skin of a patient.
US11337992B2 Liquid composition for use in the treatment of gastroesophageal reflux
The present invention relates to a liquid composition for use in the treatment of gastroesophageal reflux. The composition of the present invention comprises a mixture which comprises or, alternatively, consists of a combination of Aloe vera gel, hyaluronic acid and honey and, optionally, food or pharmaceutical grade additives and/or technological excipients. The composition of the present invention also relates to a medical device comprising a mixture which comprises or, alternatively, consists of a combination of Aloe vera gel, hyaluronic acid and honey and, optionally, food or pharmaceutical grade additives and/or technological excipients. Said composition or composition for a medical device being for use in the preventive and/or curative treatment of the symptoms associated with gastroesophageal reflux and the disease caused thereby, as well as for use in the preventive and/or curative treatment of gastroesophageal reflux disorders.
US11337991B2 Methods for the treatment and prophylaxis of HIV and AIDS
The present invention is directed to methods for inhibition of HIV reverse transcriptase, treatment of infection by HIV, prophylaxis of infection by HIV, and the treatment, prophylaxis and/or delay in the onset or progression of AIDS or ARC by administering a compound of structural Formula I or a pharmaceutically acceptable salt or co-crystal thereof, wherein X is —F or —Cl, less frequently than once daily.
US11337990B2 Human milk oligosaccharides to promote growth of beneficial bacteria
Disclosed are nutritional compositions including human milk oligosaccharides that can be administered to individuals including preterm infants, infants, toddlers, and children for improving gastrointestinal function and tolerance, as well as the growth of beneficial bacteria. Additional suitable methods of using the nutritional compositions including the human milk oligosaccharides are also disclosed.
US11337985B2 Pharmaceutical composition for use in the prophylactic and/or therapeutic treatment of L-DOPA-induced dyskinesia
Pharmaceutical composition for use in the prophylactic and/or therapeutic treatment of dyskinesias induced by L-DOPA. The present invention relates to the pharmaceutical field, more particularly to the use of Rho kinase inhibitors for treating or preventing dyskinesias induced by L-DOPA.
US11337983B2 Dactinomycin compositions and methods for the treatment of acute myeloid leukemia
The disclosure provides a method for treating NPM1-mutated acute myeloid leukemia (AML) by administration of a composition comprising dactinomycin.
US11337982B2 Combined treatment with a TLR7 agonist and an HBV capsid assembly inhibitor
The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of a TLR7 agonist and an HBV capsid assembly inhibitor for use in the treatment of chronic hepatitis B patient.
US11337981B2 Dual CLK/CDK1 inhibitors for cancer treatment
The disclosure generally relates to substituted purine analogs that are dual CLK2/CDK1 inhibitors or more potent and specific CLK inhibitors to target CLK2 and CDK1 kinases. These compounds may be useful in the treatment of germ-line mutations of the spliceosome leading to the development of cancers and other human disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US11337978B2 Stable lyophilisates comprising 5,10-methylene-(6R)-tetrahydrofolic acid
The present invention is directed to stable lyophilisates comprising 5,10-methylene-(6R)-tetrahydrofolic acid or a pharmaceutically acceptable salt thereof and a dicarboxylic acid, or a salt thereof, as well as, a processes of obtaining the same, and the use of such products.
US11337977B2 Pharmaceutical compositions comprising Akt protein kinase inhibitors
The present invention relates to pharmaceutical compositions comprising Akt protein kinase inhibitors with therapeutic activity against diseases such as cancer as well as processes for their preparation and their use as medicament.
US11337970B2 Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
US11337969B2 Methods for treating cancer
The present invention relates to methods of treating patients with advanced forms of cancer, such as unresectable or metastatic renal cell carcinoma or kidney cancer, in which X4P-001 or a pharmaceutically acceptable salt thereof is administered as monotherapy or in combination with an immune checkpoint inhibitor, such as nivolumab. The methods demonstrate surprising results, including regression of disease, with comparatively little toxicity.
US11337968B2 Phenylquinoline compositions for treatment of ocular disorders and conditions
Compositions containing a phenylquinoline derivative compound having peroxisome proliferator-activated receptor a (PPARα) agonistic activity, and methods of their use in enhancing PPARα activity in retinal cells, and in treating ocular disorders or conditions, such as but not limited to retinal inflammation, retinal neovascularization, retinal vascular leakage, retinopathy of prematurity, diabetic retinopathy, age-related macular degeneration, and diabetic macular edema are disclosed.
US11337960B2 Methods and compositions for the treatment of pre-diabetes, diabetes and metabolic syndrome
The disclosure provides thiol-containing alkyl fatty acid compound formulations for intravenous, parenteral or oral administration. The compositions of the present technology have optimal controlled bioavailability and are useful for treating metabolic dysfunctions such as pre-diabetes, Metabolic Syndrome and diabetes. Also provided are methods of treatment comprising the daily administration of the disclosed thiol-containing alkyl fatty acid formulations.
US11337956B2 IRE-1α inhibitors
Compounds which directly inhibit IRE-1α activity in vitro, prodrugs, and pharmaceutically acceptable salts thereof. Such compounds and prodrugs are useful for treating diseases associated with the unfolded protein response or with regulated IRE1-dependent decay (RIDD) and can be used as single agents or in combination therapies.
US11337955B2 Compositions and methods to regulate hormonal cascades in stress disorders
The invention is composition and methods that restore balance to the stress-related steroidal hormone cascade. Upon co-administration, the compounds of the invention restore balance to the cascade and promote or restore normal function in patients suffering from a disorder having a primary psychological stress component. The compositions include a selected combination of isoflavones, alpha lipoic acid, and L dopamine or a precursor thereof, and are preferably obtained from the natural sources disclosed herein. The uses of the invention include administration of the disclosed compositions to patients suffering from PTSD, fibromyalgia, endometriosis, and other disorders having a common chronic stress component.
US11337954B2 Apparatuses, methods, and systems for extraction, isolation and conversion of various cannabinoids, and modifications of whole-plant hemp extracts therewith
Apparatuses, methods, and systems for extraction, isolation, purification, and conversion of various cannabinoids, and modifications of whole-plant hemp extracts therewith are presented. A method for preparing a whole-plant hemp extract based product includes extracting cannabinoids from plant materials, such as one or more hemp varieties of Cannabis sativa. The method also includes separating and purifying CBD from the extracted cannabinoids, converting purified CBD to Δ9-THC and Δ8-THC and concurrently converting Δ9-THC to CBN, purifying and separating the CBN, and combining the purified CBN with a whole-plan hemp extract. Products and supplements related to the method are also described.
US11337951B2 Biologically active cannabidiol analogs
Biologically active cannabidiol analogs comprising a compound of the formula wherein one of R1 or R2 or both is/are the residue of a moiety formed by the reaction of an amino group of the amino acid ester of R1 or R2 or both with a dicarboxylic acid or a dicarboxylic acid derivative and the other R1 or R2 (in the case of the mono) is the residue of a dicarboxylic acid or dicarboxylic acid derivative or Hydrogen (H), (i.e. underivatized), and salts thereof. These CBD analogs are be useful in pain management in oncology and other clinical settings in which neuropathy is presented. Furthermore, these CBD-analogs are useful in blocking the addictive properties of opiates.
US11337947B2 Composition for inhibiting growth of bacterium having menaquinone synthesis pathway through futalosine or futalosine derivative
The present invention provides a composition for inhibiting proliferation of a bacterium provided with a menaquinone synthesis route via futalosine or a futalosine derivative, which contains a fatty acid having 18 carbon atoms and a hydroxyl group at the 10-position as an active ingredient. Furthermore, the present invention provides a composition for preventing or treating a disease caused by a bacterium provided with a menaquinone synthesis route via futalosine or a futalosine derivative.
US11337946B2 Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related diseases
Composition for promoting mitochondrial biogenesis and improving mitochondrial function in a subject, the composition comprising an active agent, said active agent containing the amino acids leucine, isoleucine, valine, threonine, lysine and citric acid, succinic acid, malic acid.
US11337943B2 Lacosamide pharmaceutical composition and dosage form thereof
A dosage form of lacosamide and a pharmaceutical dosage form thereof is disclosed. The dosage form includes an extended release portion and optionally an immediate release portion. Also provided are methods of providing extended release of lacosamide and treatment of a neurological or psychiatric disease or condition.
US11337938B2 Epinephrine formulations
Pharmaceutical compositions comprising epinephrine, methods of administration, and methods of making the same. Compositions may comprise at least one of an active agent, a pH raising agent, an antioxidant, a transition metal complexing agent, a pH lowering agent, a tonicity regulating agent, optionally a preservative, and optionally a solvent.
US11337937B2 TARR receptor agonists for sexual dysfunction
The present invention discloses compositions, methods, and systems of treating female sexual dysfunction by stimulating the contraction of the smooth muscle of the nipple. The smooth muscle in the nipple expresses trace amine associated receptors and thus can be contracted through a class of trace amine associated receptor agonists such as octopamine or tyramine, but any agent that promotes contraction of smooth muscle can be considered for the methods and compositions described herein. The contraction of the smooth muscle erects the nipple and increases female sexual arousal. The smooth muscle stimulatory compound can be formulated in a solution, foam, ointment, gel, spray, lotion, powder, topical cream, emulsion, slow release capsule or any similar method, compound, or delivery vehicle including a pre-wetted gauze or cotton pad. Additionally, the disclosed composition can be used to improve the quality of a sexual experience, e.g., it can increase orgasm intensity or a subject's interest in sex, of females that do not suffer from sexual dysfunction.
US11337935B2 Identification of stabilizers of multimeric proteins
Disclosed herein are compounds and compositions thereof which find use in increasing stability of TTR tetramers reducing its tendency to misfold and form aggregates. Also provided herein are methods for using these compounds and compositions for increasing stability of TTR and thereby decreasing aggregate formation by TTR. Also disclosed herein are methods to screen for candidate compounds that increase stability of TTR. Also disclosed herein are heterobifunctional compounds that include a TTR binding compound connected to a targeting moiety via a linker, for use in disrupting PPIs of a target protein.
US11337931B2 Nanoparticle delivery system for diseases associated with major basement membrane components of blood vessels accessible from blood stream
A targeting nanoparticle composition and method of treatment for diseases associated with major basement membrane components of blood vessels accessible from blood stream is presented. The composition includes pegylated perfluorocarbon nanoparticles having a targeting ligand attached that targets the basement membrane components, specifically collagen IV. The targeted nanoparticles may contain at least one pharmaceutically active agent capable of treating a glomerular disease such as lupus nephritis.