最新美国发明专利第2022-05-24期 - 专利汇|PatentHub专利检索|专利查询网|发明专利查询分析

Document	Document Title
US11339445B2	Method for detecting Tac2 gene sensitive to low-level ionizing radiation, and gene detected by the method A method for detecting genes sensitive to low-level ionizing radiation and genes detected by the method. More specifically, genes sensitive to low-level ionizing radiation and related to suppressing thymic cancer, discovered in a carcinogenic entity and verified in a normal entity are detected by subjecting a cancerous AKR/J mouse and a normal ICR mouse to low-level radiation. Thymus is collected therefrom, immunogenic and apoptotic genes are classified via microarray processing of the thymus. The genes are amplified and the levels of gene expression are measured. Thus, a gene having a specific reaction to radiation can be accurately detected by preventing the interference of confounding variables.
US11339441B2	Profiling chemically modified DNA/RNA units for disease and cancer diagnosis The present invention relates to high-throughput methods comprising direct infusion electrospray ionization mass spectrometry (ESI-MS), multistep tandem mass spectrometry (MSn), consecutive reaction monitoring (CRM), ion mobility spectrometry mass spectrometry (IMS-MS), high-resolution MS, and IMS-MS, for genome-wide (whole cell or tissue) profiling of DNA and RNA nucleotides/nucleosides having a wide variety of variant structural modifications. In particular, these methods are contemplated for providing a specific profile of variant DNA and/or RNA chemically modified nucleic acids (i.e. structures) associated with specific medical conditions. Medical conditions may include, but are not limited to: cancer; including prostate, lung, uterus, larynx, ovary, breast, kidney, and many other types of cancers; specific stages of cancer; bacterial infections; viral infections; genetic and metabolic disorders; and any condition involving changes in DNA and/or RNA structural modifications.
US11339440B2	Micro-RNA signatures for the prediction of liver dysfunction The invention relates to an in vitro method of determining a subjects risk of liver dysfunction, specifically after partial liver resection, said method comprising the steps of providing a sample from said subject, determining in said sample the expression level of at least one miRNA, selected from the group consisting of miR-151a, miR-192 and miR-122, and comparing these expression level(s) with at least one reference expression level, or identifying the ratios of the expression levels of miR-15 la to miR-192 and/or of miR-122 to miR-151a and comparing said expression level ratios with reference expression level ratios, and classifying the sample from the outcome of the comparison into one of at least two classes, wherein each class is one of the at least two categories “high-risk” and “low-risk”.
US11339439B2	Methods and compositions for screening and treating developmental disorders This document provides methods and materials related to genetic variations of developmental disorders. For example, this document provides methods for using such genetic variations to assess susceptibility of developing Autism Spectrum Disorder.
US11339436B2	Methods for early identification of bone healing ability in injured patients The present invention relates to the discovery that the expression levels of some RNA molecules, comprising messenger RNA (mRNA), non-coding RNA (ncRNA) and/or microRNA (miRNA), and protein can be used as a diagnostic signature to predict or monitor the bone healing ability in an acutely injured subject or in a chronic nonunion subject. In certain embodiments, the invention relates to methods and compositions useful for differentiating between a nonunion, slow healing, and/or normal healing of a fractured bone and treatment recommendations. The invention further includes a kit comprising biomarker probes for assessing the bone healing ability in an acutely injured subject or in a nonunion subject after receiving therapeutic treatment.
US11339434B2	Methods for determining gene functions Disclosed herein are methods, systems and compositions for determining substrate specificity of an enzyme. The disclosed methods, systems and compositions can be used for identifying enzymes capable of modifying substrates of interest and/or quantifying enzymatic activity.
US11339433B2	Nucleic acid sequencing systems Methods and systems for sequencing a nucleic acid molecule are described that comprise imaging a first surface and an axially-displaced second surface using a compensation-free optical system, the system comprising an objective lens and at least one image sensor, wherein said optical system has a numerical aperture (NA) of less than 0.6 and a field-of-view (FOV) of greater than 1.0 mm2; and) processing the images of the first surface and the axially-displaced second surface to correct for optical aberration such that the images of the first surface and the axially-displaced second surface have substantially the same optical resolution.
US11339431B2	Methods and compositions for enrichment of target polynucleotides High-fidelity, high-throughput nucleic acid sequencing enables healthcare practitioners and patients to gain insight into genetic variants and potential health risks. However, previous methods of nucleic acid sequencing often introduce sequencing errors (for example, mutations that arise during the preparation of a nucleic acid library, during amplification, or sequencing). Provided herein are methods and compositions for sequencing nucleic acids. Further provided are methods of identifying an error in a nucleic acid sequence.
US11339430B2	Methods and apparatus for measuring analytes using large scale FET arrays Methods and apparatus relating to very large scale FET arrays for analyte measurements. ChemFET (e.g., ISFET) arrays may be fabricated using conventional CMOS processing techniques based on improved FET pixel and array designs that increase measurement sensitivity and accuracy, and at the same time facilitate significantly small pixel sizes and dense arrays. Improved array control techniques provide for rapid data acquisition from large and dense arrays. Such arrays may be employed to detect a presence and/or concentration changes of various analyte types in a wide variety of chemical and/or biological processes. In one example, chemFET arrays facilitate DNA sequencing techniques based on monitoring changes in hydrogen ion concentration (pH), changes in other analyte concentration, and/or binding events associated with chemical processes relating to DNA synthesis.
US11339429B2	Methods for non-invasive prenatal ploidy calling The present disclosure provides methods for determining the ploidy status of a chromosome in a gestating fetus from genotypic data measured from a mixed sample of DNA comprising DNA from both the mother of the fetus and from the fetus, and optionally from genotypic data from the mother and father. The ploidy state is determined by using a joint distribution model to create a plurality of expected allele distributions for different possible fetal ploidy states given the parental genotypic data, and comparing the expected allelic distributions to the pattern of measured allelic distributions measured in the mixed sample, and choosing the ploidy state whose expected allelic distribution pattern most closely matches the observed allelic distribution pattern. The mixed sample of DNA may be preferentially enriched at a plurality of polymorphic loci in a way that minimizes the allelic bias, for example using massively multiplexed targeted PCR.
US11339428B2	Increased signal to noise in nucleic acid sequencing A method for identifying a nucleotide in a template nucleic acid by (a) providing a plurality of primer-template nucleic acid hybrids, wherein the primers have an extendable 3′ end; (b) contacting the plurality with: (i) blocked nucleotides to produce a first subset of the primer-template nucleic acid hybrids that include a blocked nucleotide at the 3′ end, and (ii) a ternary complex inhibitor to produce a second subset of the primer-template nucleic acid hybrids that include a ternary complex inhibitor; (c) forming ternary complexes that each include a polymerase, a primer-template nucleic acid hybrid of the first subset, and a cognate nucleotide; and (d) detecting the ternary complexes, thereby identifying a nucleotide in the template nucleic acid.
US11339426B2	Method capable of differentiating fetal sex and fetal sex chromosome abnormality on various platforms The present invention relates to a method capable of, in order to diagnose fetal sex chromosome aneuploidy, differentiating Kleinfeiter's syndrome (XXY), triple X syndrome (XXX), and Turner's syndrome (monosomy X, XO) as well as male (XY) and female (XX) by using copy number variation (CNV). The differentiation method according to the present invention has significantly high sensitivity and accuracy since the reference line is evenly adjusted by performing normalization regardless of the kinds of platform and data. The present invention is useful in diagnosing the sex chromosome abnormality at an early stage through easy diagnosis of sex chromosomes X and Y, which are hard to diagnose, since an analysis is possible even with a small amount of fetal chromosomes, which corresponds to an advantage of noninvasive prenatal diagnosis, and copies are redundant.
US11339424B2	Method for amplification and quantitation of small amount of mutation using molecular barcode and blocking oligonucleotide The present disclosure relates to a method for amplification and quantitation of a small amount of mutation using a molecular barcode and a blocking oligonucleotide.
US11339422B2	Methods of analyzing nucleic acids Presented herein are methods and compositions for analyzing rare nucleic acid species. Some methods presented herein use DNA reassociation kinetics following thermal denaturation to define populations of nucleic acid sequences, e.g., highly abundant (e.g., cDNA from rRNA), moderately abundant, and less abundant or rare sequences (e.g., cDNA from mRNA).
US11339420B2	Fluorescence-based reporters for mutagenesis detection in E. coli Direct detection of mutagenesis in prokaryotes by reversion of an inactivating mutation (reversion mutation assay), producing a quantitative signal for in vivo mutagenesis, may greatly reduce the amount of test chemicals and labor involved in these assays. Further, transcriptional coupling of β-lactamase reversion and GFP, translational fusion between β-lactamase and GFP with stop codon in GFP, and a novel dual reporter to monitor continuous mutagenesis may be used in methods described herein.
US11339418B2	Antimicrobial susceptibility testing and microbial identification Systems and methods for microbe identification (ID) in the context of phenotypic antimicrobial susceptibility testing (AST). Approaches for rapidly identifying polymicrobial samples are introduced that following perform one or more ID methods, such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF), PCR, or DNA hybridization, following sample incubation in two or more different media, including at least one selective media. Parallel ID and AST workflows are provided that may reduce the time from sample to AST result.
US11339416B2	Inline sensor arrangement, and method for producing and commissioning said inline sensor arrangement The present disclosure relates to an inline sensor arrangement for the detection of measurement values of a measurand representing an analyte content of a measuring medium, which arrangement comprises: a sensor which is designed to generate and output a measurement signal correlated with the measurand, wherein the sensor has at least one sterile sensor element provided for contact with the measurement medium; and a housing surrounding the at least one sensor element, which housing encloses the sensor element in a chamber sealed tightly against an environment of the housing, and wherein the chamber contains inside it a gas volume that is designed such that an influence of harmful substances—in particular, of reactive nitrogen and/or oxygen species—on the at least one sensor element is largely prevented. The present disclosure further relates to a method for the production of said inline sensor arrangement, and for its commissioning.
US11339407B2	Systems and methods for point/center-of-care immunotherapy A cell modification device, comprising a centrifugation chamber with at least one cell modifying surface with a normal vector having an angle of 135-45° to the rotational axis of the centrifugation chamber, wherein the centrifugation chamber comprises at least one input/output port and the cells to be modified are immobilized at the cell modifying surfaces by the rotation of the centrifugation chamber at 2 to 2000 g. In an embodiment, the device is used as a point-of-care and/or portable device. Further, the present disclosure describes software that, when executed by a processor, causes the device to perform the disclosed functions.
US11339405B2	Kit and method for producing induced embryonic neural progenitors Disclosed herein are kits comprising transcription factors for inducing a fibroblast cell into an induced embryonic neural progenitor cell. The induced embryonic neural progenitor cell is then capable of differentiating into an astrocyte, an oligodendrocyte or a neuron. Also disclosed are the uses of the kit as a platform for selecting a drug candidate to treat neurological diseases.
US11339401B2	Gene for controlling erectness growth of rice leaf blades and application thereof A method for controlling the building of architecture of gramineous crops and application thereof. The gene CYC U4;1 (Os10g41430) has a specific expression in a rice pulvinus (which is believed to have a specific expression in other gramineous crops), with a CDS sequence as shown in SEQ ID NO: 2, and an encoded amino acid sequence as shown in SEQ ID NO: 3. Also a promoter sequence of the gene, with the sequence as shown in SEQ ID NO: 1. Transgenic lines obtained by cloning a promoter and full-length CDS of CYC U4;1 to pCAMBIA1301 and transferring this into rice Nipponbare are all characterized by having smaller leaf-stem angles than those of wild rice, accordingly, the expression level of the gene CYC U4;1 can be increased or decreased with genetic engineering technology to control the plant architecture development, thereby improving the plant architecture and increasing the density of germplasm.
US11339399B2	Compositions and methods for high efficiency in vivo genome editing The present invention provides cell lines for high efficiency genome editing using cas/CRISPR systems, methods of generating such cells lines, and methods of generating mutations in the genome of an organism using such cell lines.
US11339393B2	Compositions for modulating C9ORF72 expression Disclosed herein are compositions and methods for reducing expression of C9ORF72 mRNA and protein in an animal with C9ORF72 specific inhibitors. Also disclosed herein are compositions and methods of selectively inhibiting a C9ORF72 pathogenic associated mRNA variant by administering an antisense compound targeting the region beginning at the start site of exon 1A to the start site of exon 1B of a C9ORF72 pre-mRNA. Such methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof. Such C9ORF72 specific inhibitors include antisense compounds.
US11339392B2	Pan-genotypic agents against influenza virus and methods of using the same Methods of inhibiting influenza A virus in a sample are provided. Aspects of the methods include contacting a sample comprising viral RNA (vRNA) having a PSL2 motif with an effective amount of an agent that specifically binds the PSL2 motif to inhibit the influenza A virus. Also provided are methods of treating or preventing influenza A virus infection in a subject. Also provided are methods for screening a candidate agent for the ability to inhibit influenza A virus in a cell, the method comprising: contacting a sample with a candidate agent; and determining whether the candidate agent specifically binds to the PSL2 motif of vRNA. Also provided are compounds and pharmaceutical compositions comprising an oligonucleotide sequence complementary to a PB2 vRNA region that find use in the subject methods.
US11339391B2	High efficiency construction of DNA libraries The invention provides a method for efficient DNA library construction and targeted genetic analyses of the libraries.
US11339390B2	DNA microscopy methods The present invention relates to DNA microscopy methods to record the cellular co-localization and/or spatial distributions of arbitrary nucleic acid sequences, or other biomolecules tagged with nucleic sequences. The method involves sequence-components which may identify the targeted sequences-of-interest themselves and/or spatial beacons relative to which their distances are measured.
US11339389B2	Semi-synthetic nurse shark VNAR libraries for making and using selective binding compounds The present invention relates to VNAR single chain antibodies and more particularly, to semi-synthetic VNAR libraries derived from nurse shark which may be used to identify individual clones, nucleic acid molecules and polypeptides which encode binding moieties that specifically bind to a cellular target of interest, thereby altering (e.g., antagonizing) target activity in a cell or mimicking the activity of a native molecule. The present invention thus also relates to compounds and compositions comprising a target specific VNAR binding moiety, methods for preparing them, and diagnostic and therapeutic methods of use relating to regulation, e.g., agonism or antagonism of the selected cellular target or target pathway e.g., to treat and/or prevent a pathological condition, disorder or disease in which it is beneficial to alter, e.g., agonize or augment, antagonize, reduce or eliminate the specific cellular target activity.
US11339388B2	Methods and compositions for generation of binding agents against cell surface antigens Provided are methods and compositions for identifying binding polypeptides (e.g., antibodies or antigen binding fragments thereof) that specifically binds to a cell-surface antigen. The methods of the invention generally comprise contacting a variegated nucleic acid-display library of binding polypeptides with a cell-surface antigen displayed on the exterior surface of a cell; and isolating from the library at least one library member that specifically binds to the cell-surface antigen on the exterior surface of the cell. Also provided are novel nucleic acid display libraries (e.g., DNA display libraries) useful in the methods of the invention.
US11339382B2	Recombinase polymerase amplification The present invention features novel, diverse, hybrid and engineered recombinase enzymes, and the utility of such proteins with associated recombination factors for carrying out DNA amplification assays. The present invention also features different recombinase ‘systems’ having distinct biochemical activities in DNA amplification assays, and differing requirements for loading factors, single-stranded DNA binding proteins (SSBs), and the quantity of crowding agent employed.
US11339380B2	Glutamate dehydrogenase mutant and application thereof The invention discloses a glutamate dehydrogenase mutant and an application thereof. The mutant is one of the following: a mutant of the amino acid sequence of SEQ ID NO. 1 which has a mutation at lysine at position 402 to phenylalanine or aspartic acid; a mutant which has a mutation at isoleucine at position 406 to phenylalanine or threonine; a mutant which has a mutation at threonine at position 121 and leucine at position 123; a mutant which has a mutation at alanine at position 379 and leucine at position 383. In the invention, the catalytic activity of glutamate dehydrogenase derived from Pseudomonas putida to 2-carbonyl-4-(hydroxymethylphosphonoyl)butanoic acid (PPO) is significantly improved by a molecular transformation method combining directed evolution and a semi-rational design; and the issue of low glutamate dehydrogenase activity in the process of preparing L-glufosinate by reductive amination is solved.
US11339372B2	Serum-free medium inducing differentiation of umbilical cord mesenchymal stem cell into insulin-secretion-like cell and preparation method and use thereof Provided is a new type serum-free medium. The medium comprises: DMEM with high glucose (the content of glucose being 4.5 g/L), B27, recombinant human basic fibrolast growth factor (b-FGF), nicotinamide, N-2, vinblastine III (conophylline), non-essential amino acid (NEAA), heparin, epidermal growth factor (EGF), hepatocyte growth factor (HGF), a serum replacement (SR), an insulin-transferrin-selenium complex (ITS), and pentagastrin. Inducing differentiation of mesenchymal stem cells into insulin-secretion-like cells can be achieved in six days in one step using the medium.
US11339368B2	Cultured tobacco cells as a matrix for consumable products Various embodiments are directed to consumable products incorporating a matrix of cultured tobacco cells. Any tobacco variety may be utilized for establishing in vitro tobacco cultures, including native tobacco varieties and genetically modified tobacco varieties derived from any tobacco variety. Various embodiments are directed to methods for producing tobacco products incorporating cellular material and/or extracts derived from tobacco cells cultured in vitro.
US11339365B2	Nanopore sensor for enzyme-mediated protein translocation Described herein is a device and method for translocating a protein through a nanopore and monitoring electronic changes caused by different amino acids in the protein. The device comprises a nanopore in a membrane, an amplifier for providing a voltage between the cis side and trans side of the membrane, and an NTP driven unfoldase which processed the protein to be translocated. The exemplified unfoldase is the ClpX unfoldase from E. coli.
US11339363B2	Dendritic cell generating apparatus and method A cell culture cartridge is provided comprising a plurality of zones geometrically configured to provide for symmetrical fluid flow with each of the plurality of zones to avoid dead areas in flow within each of the plurality of zones. In certain embodiments, at least eight inlets are provided, with an inlet positioned at each corner of the cell culture cartridge. In certain embodiments, a shared outlet is positioned on a top surface of the cell culture cartridge.
US11339361B2	Additive manufacturing of functional myocardial tissue A bioreactor and methods for use can include a microfibrous scaffold, that can be made of a composite bioink, and that can have endothelial cells directly embedded within the scaffold using an additive manufacturing process. The scaffold can further be seeded with cardiomyocytes. The hydrogel scaffold can be composed of a plurality of serpentine layers, with each serpentine layers, which can be placed on each other in a cross-hatch configuration, so that the primary axes of successive layers are perpendicular. This configuration can establish an aspect ratio for the scaffold, which can be selectively varied. For greater strength, the successive layers that have a primary axis in the same direction can be placed in the scaffold so that they are slight offset from each other. The scaffold can be placed in the bioreactor with perfusion, for use in cardiovascular drug screening and other nanomedicine endeavors.
US11339360B2	Culture systems and methods of using same Culture systems and methods of using same. The systems include a housing defining an inner space. The inner space includes a headspace and at least a portion of a reservoir. A surface for immobilizing cells is moveable between the headspace and the reservoir. The systems can be used for coculturing methanotrophs and phototrophs for processing biogas and wastewater, particularly from anaerobic digesters.
US11339358B2	Pouring spout for bottled liquids Pouring spouts used to filter bottled liquids as they are poured from a bottle containing such liquids.
US11339353B2	Acidic hard surface cleaner with glycine betaine ester Cleaning compositions that include (a) a glycine betaine ester, (b) an acidifying agent, (c) polysaccharide thickener, and (d) water, are provided. Commonly, the glycine betaine ester may include one or more compounds of formula (I): Me3N+—CH2—C(O)—O—R X− wherein R is an aliphatic group having 8 to 22 carbon atoms and X″ represents an inorganic or organic anion. Commonly, the composition has a pH of no more than about 4, a viscosity of no more than about 1,500 cP at a shear rate of 10 at 25° C., and/or a viscosity of at least about 250 cP at a shear rate of 50 at 25° C. (where the viscosities are determined with a Brookfield Cone/Plate viscometer). The cleaning composition may exhibit a unique sheer thinning profile, such that the composition thins less after being sprayed onto a surface and thereby providing a longer contact time than conventional cleaning products.
US11339352B2	Antimicrobial hard surface cleaners comprising alkylpyrrolidones The need for an antimicrobial hard surface cleaning composition which provides improved removal of greasy residues, especially greasy soap scum, is met by formulating the antimicrobial hard surface cleaning composition with an alkyl pyrrolidone surfactant and additional nonionic surfactant.
US11339346B2	Use of polyesters as viscosity index improvers for aircraft hydraulic fluids The invention is related to a composition for use in hydraulic systems of an aircraft. The composition typically comprises an adipic acid-based polyester in a phosphate ester base stock substantially consisting of trialkyl phosphates.
US11339341B1	Biofuel product with fat, oil and/or grease components A biofuel product having constituents selected from the group including fat, oil and/or grease components. A container is formed of a biodegradable material having a multiplicity of openings of a size and shape adapted for allowing the fat, oil and/or grease components to pass through the openings to an interior area of the container. An absorbent capture material is positioned in the container and holds a quantity of the fat, oil and/or grease. The container, capture material and fat, oil and/or grease collectively comprise the biofuel product.
US11339340B2	Flavor briquet A flavor or aroma charcoal material, such as charcoal briquets, which is formulated to include a flavor or aroma component. The charcoal material may include a smoldering agent (e.g., limestone), wood particles (e.g., sawdust), a binder, and the flavor or aroma component (herbs and/or spices). The flavor or aroma charcoal material may not be configured as a fuel charcoal material, for example, it may be substantially void of char and/or coal. In an embodiment, the flavor or aroma charcoal material may be provided as part of a blend of different charcoal materials that includes both flavor or aroma briquets in combination with fuel briquets (e.g., which fuel briquets include char and/or coal, while the flavor briquets do not). The flavor briquets provide enhanced aroma and/or flavor to the grilling experience.
US11339339B1	Condensate stabilization process A natural gas processing system is configured to process a two-phase flow in a natural gas transportation system. The natural gas processing system has an off-gas compression package with a compressor suction drum, joined to a stabilizer and to a first stage compressor. A first stage off-gas after cooler is joined to the compressor suction drum and a second stage off-gas suction drum. The second stage off-gas suction drum is operatively coupled to a two-phase separator. A second stage compressor is joined to the second stage off-gas suction drum and a second stage off-gas after cooler. The second stage off-gas after cooler is operatively coupled to an acid gas removal system. The off-gas compression package separates the liquid phase from an off-gas phase.
US11339338B2	Fuel blending component composition and method for reducing criteria emissions The disclosure provides a fuel formulation that, as a blending component, at a certain blending volume range, with transportation fuels significantly reduces criteria emissions (i.e., particle number (PN) emissions, Nitrogen Oxides (NOx) emissions, Total Hydrocarbon (THC) emissions) when compared to existing market fuels. The fuel blending component formulation comprises one or more branched alkane components, one or more cyclic alkane components, one or more alkylate component and one or more oxygenate component. The fuel blending component composition achieves reductions on a spark ignition engine (SI) of more than 60% in particulate emissions, up to 30% in NOx emissions, and up to 20% in THC emissions when blended with a reference gasoline in concentrations as low as 10% by volume. A method for reducing criteria emissions is also provided.
US11339336B2	Integrated aromatic separation process with selective hydrocracking and steam pyrolysis processes Aromatics extraction and hydrocracking processes are integrated with a stream pyrolysis unit to optimize the performance of the hydrocracking units by processing the aromatic-rich and aromatic-lean fractions separately in order to better control the hydrocracking operating severity and/or catalyst reactor volume design requirements.
US11339331B2	Biogenic low viscosity insulating oil A method of producing a non-petroleum based electrical insulating oil, wherein the method can include providing a primary mixture of non-petroleum origin, containing isomerized straight chain hydrocarbons; performing a distillation and/or stripping of the primary mixture; collecting a paraffinic base oil as a product of the distillation and/or stripping, containing a mixture of isoalkanes and alkanes; and mixing the base oil with an antioxidant additive.
US11339330B2	Method and apparatus for producing biofuel The present invention relates to the field of renewable energy. More specifically, the present invention relates to the production of biofuel from biomass including, for example, polymeric materials.
US11339329B2	Polarizer and image display device Provided is a polarizer having a high degree of alignment and an image display device including the polarizer. The polarizer is formed of a polarizer-forming composition containing a polymer liquid crystal compound and a dichroic material, in which the polymer liquid crystal compound is a thermotropic liquid crystal and a crystalline polymer, the polymer liquid crystal compound and the dichroic material are horizontally aligned, and crystallinity of the polymer liquid crystal compound in the polarizer-forming composition is higher than the crystallinity of the polymer liquid crystal compound alone.
US11339323B2	Lightweight proppant and methods for making and using same Lightweight proppant particles are disclosed. The lightweight proppant particle can include a proppant particle having an apparent specific gravity of at least about 1.5 g/cc, a coating of a hydrophobic material formed on an outer surface of the proppant particle, and a coating of an amphiphilic material formed on an outer surface of the coating of the hydrophobic material.
US11339321B2	Reactive hydraulic fracturing fluid Hydraulic fracturing fluids and methods to hydraulically fracture a subterranean formation and oxidize organic material in the subterranean formation. The hydraulic fracturing fluid includes water, another fluid, and a surfactant. An inorganic oxidizer is included in the water.
US11339317B1	Method of drilling a wellbore A method of minimizing the weight loss of mass of the drilling pipe and wellbore casing while drilling a subterranean well with an oil-based drilling fluid comprising adding to the oil-based drilling fluid an anti-wear additive based on sulfated, sulfonated or sulfited natural oils or fats of vegetable or animal origin.
US11339315B2	Non-combustible mixed refrigerant having low greenhouse effect and application thereof A non-combustible mixed refrigerant having a low greenhouse effect and an application thereof, the mixed refrigerant comprises the following components in mass fractions: 4-31.5% of R125, 50-80% of R1234ze (E) and 12-22% of R1234yf. Under the cooperation of each component dosage range, the mixed refrigerant becomes non-combustible, the ODP is 0, and the GWP is not greater than 1000. The present invention may be used in a refrigeration system, does not destruct ozone, reduces the greenhouse effect, and has a low slip temperature, relating to ternary azeotropic or near-azeotropic refrigerants, and being beneficial for the stable operation of a refrigeration system. The mixed refrigerant may also be used as a foaming agent or an aerosol propellant, and has the advantages of being non-combustible, having a low ozone destruction index, and being environmentally friendly, safe and reliable.
US11339314B2	Composition for heat cycle system, and heat cycle system To provide a composition for a heat cycle system comprising trifluoroethylene (HFO-1123), which has a low global warming potential and excellent cycle performance of HFO-1123 and which has high durability, and a heat cycle system employing the composition, which has less influence over global warming and has both high cycle performance and durability.A composition for a heat cycle system, which comprises a working fluid for heat cycle containing trifluoroethylene, and a radical scavenger, and a heat cycle system employing the composition for a heat cycle system.
US11339312B2	Polishing composition, production method of the same, polishing method, and manufacturing method of semiconductor substrate The present invention provides means capable of improving an effect of inhibiting polishing of silicon nitride. The present invention relates to a polishing composition containing a cationically modified silica particles, a non-aromatic crosslinked cyclic compound having an organic acid group or a group of a salt thereof, and water.
US11339310B2	Polishing composition The present invention provides a polishing composition having a high polishing speed and a low etching speed and capable of achieving sufficient flattening.The present invention is a polishing composition containing abrasive grains, an oxidizing agent, an acid, an anticorrosive containing a compound represented by the following formula (1) or a salt thereof, and a dispersing medium. (In the formula (1), R1 is a linear or branched alkyl group having 6 or more and 30 or less carbon atoms or a linear or branched alkenyl group having 6 or more and 30 or less carbon atoms, R2 is a single bond or an alkylene group having 1 or more and 4 or less carbon atoms, and R3 is a hydrogen atom or a linear or branched alkyl group having 1 or more and 10 or less carbon atoms.)
US11339309B2	Polishing liquid and polishing method A polishing liquid is provided containing manganese oxide abrasive grains, permanganate ions, and a cellulosic surfactant or a cationic surfactant. The polishing liquid has a pH of 5 or more and 11 or less. The cellulosic surfactant is preferably a carboxymethyl cellulose or a derivative thereof. The cationic surfactant preferably has a quaternary ammonium ion site. The content of the cellulosic surfactant or the cationic surfactant is preferably 0.01 mass % or more and 1.0 mass % or less based on the total amount of the polishing liquid.
US11339305B2	Substrate coated with non-stick coating resistant to abrasion and scratching A substrate coated with a non-stick fluoropolymer coating is provided, the coating having excellent abrasion and scratch resistance. The coating contains: i.) a continuous primer layer adhered to the substrate containing a polymer binder, a first fluoropolymer and first inorganic film hardner particles, ii.) a discontinuous midcoat layer containing aggregate particles adhered to the primer layer and distributed discontinuously across the surface of the primer layer so as to reveal exposed areas of the surface of the primer layer, wherein a portion of the aggregate particles are in clusters, and wherein the aggregate particles contain second fluoropolymer and second inorganic film hardner particles, and iii.) a topcoat layer containing a third fluoropolymer adhered to the midcoat layer and the exposed areas of the surface of the primer layer at points where there is no midcoat layer.
US11339303B2	Energy curable compositions comprising reaction products of poly(alkylene oxide)-containing glycidyl ethers and acrylic acid The present invention is drawn to low migration energy-curable compositions including epoxy acrylates derived from the reaction of poly(alkylene oxide) containing glycidyl ethers with acrylic acid. The compositions of the invention are particularly useful for the printing or coating of food packaging.
US11339301B2	Self adhesive fouling release coating composition A multilayer self-adhesive fouling release coating composition includes an optional removable underlying liner; an adhesive layer applied over and to the optional underlying liner when the latter is present; and a synthetic material layer applied over and to the adhesive layer. Optionally, an intermediate silicone tie coat is applied over and to the synthetic material layer. A silicone fouling release top coat is applied over and to the synthetic material layer, or, when present, over and to the intermediate silicone tie coat. Optionally, a removable polymeric film is applied over and to the fouling release top coat.
US11339296B2	Compound for use in colour change compositions Novel reaction media for electron donating and electron accepting components in colour-change compositions are described. The compound is of formula (I): wherein R1, and R2 are selected from a linear or branched alkyl group, alkenyl group, alkoxy group, aryl group and an alkylene aryl group having from 6 to 22 carbon atoms; X1 and X2 are selected from —OC(O)—, —CO2— and O; R3, R4 and R5 are selected from hydrogen and an linear or branched alkyl group, cycloalkyl group, alkenyl group, alkoxy group, aryl and alkylene aryl group; R6 is selected from hydrogen, R3, —X1R1 and aryl and halogen; Y1 Y2 Y3 and Y4 are selected from hydrogen, R3, —OR3 and halogen; a is 0 to 4; b is 0 or 1; x and y are independently is 0 or 1 provided that where x and y are 0, a is 0 and b is 1 and R6 is —CO2R1; and wherein when a is 0 and b is 1 and R5 or R6 is phenyl, R6 and R5 respectively are not hydrogen or C1-7alkyl. The compounds are useful in ink compositions, writing implements containing the compound and medical and industrial applications in which temperature sensitive colour change may be required.
US11339293B2	Non-petroleum based rejuvenating agent The invention provides a non-petroleum based rejuvenating agent to improve the performance of the recycled asphalt, and accordingly extend the service life of the recycled pavement.
US11339286B2	Thermoplastic resin composition and molded article using same Disclosed are a thermoplastic resin composition comprising, based on (A) 100 parts by weight of a base resin comprising (A-1) 75 to 90 wt % of a polycarbonate resin, (A-2) 5 to 15 wt % of an acryl-based graft copolymer, and (A-3) 5 to 15 wt % of an aromatic vinyl-vinyl cyanide copolymer, (B) 5 to 20 parts by weight of a polyamide-polyalkylene glycol copolymer, and (C) 4 to 6 parts by weight of a cross-linked aromatic vinyl-vinyl cyanide copolymer, and a molded article made using the same.
US11339283B2	Thermoplastic resin composition and laminate using the same There are provided a thermoplastic resin composition capable of bonding a cyclic polyolefin-based polymer and an ethylene-vinyl alcohol copolymer with sufficient strength and to provide a laminate using the same.
US11339282B2	Flooding composition with polytetrafluoroethyene Provided is a flooding composition. The flooding composition includes in weight percent (wt %) based on the weight of the composition: (A) from 1 wt % to less than 5 wt % of a polytetrafluoroethylene (PTFE) powder; (B) a styrene-ethylene/propylene block copolymer; and (C) a mineral oil having a kinematic viscosity from 32 cSt to 100 cSt at 40° C. Also a fiber optic cable is provided. The fiber optic cable includes a buffer tube; at least one optical fiber in the buffer tube; and the flooding composition.
US11339272B2	Additive for rubber, rubber composition, and tire using the same An additive for rubber that enables a rubber composition to have excellent low heat generating property and processability, a rubber composition containing the additive for rubber, and a tire using the same are provided. A rubber composition comprises a hydrazone compound represented by the following Formula (I): where R1 and R2 each independently represent a hydrogen atom, an alkyl group with a carbon number of 1 to 16, or an alkenyl group with a carbon number of 2 to 6, and A represents a group represented by the following Formula (A-1) or Formula (A-2):
US11339268B2	One-step, solvent-free method for recycling and reprocessing thermoset polymers with tunable properties Thermosetting plastics are recycled by process that begins with grinding the plastic into small pieces. This particulate is then mixed with a catalyst and ball mill milled to a fine powder, which can then be reprocessed via molding (e.g., hot-press, injection, etc.).
US11339262B2	Epoxy based reinforcing patches having improved damping loss factor A reinforcing sheet including one or more layers of a reinforcing material, and a thermosetting adhesive associated with the reinforcing material, wherein the thermosetting adhesive includes a curing agent, and an epoxy-modified dimerized fatty acid combined with an epoxy terminated polyurethane interpenetrating network.
US11339260B2	Pultrusion processes for producing fiber reinforced polyurethane compositions and polyurethane-forming reaction mixtures suitable for use in such processes Pultrusion processes for producing fiber reinforced polyurethane composites are described. The processes utilize a polyurethane-forming reaction mixture comprises a chelated organometallic/metalorganic catalyst. Polyurethane-forming reaction mixtures suitable for use in such processes are also described.
US11339259B2	Facile methods to manufacture intelligent graphene nanomaterials and the use of for super-light machine and vehicles This utility invention is to replace some of the parts of current vehicles and robotic machines with intelligent graphene-based fibers and nanocomposites to achieve significantly weight-decreasing and energy-savings. This invention also is related to the formation of new generation vehicles, machine parts including robotics, which include but not limited to all kinds of cars, trailers, trucks, vehicles on roads and in the sky, ships on the ocean, and intelligent robotics for Human, as well as computer parts, bicycles, and sports supplies.
US11339258B2	Resin composition, and pre-preg, metal-clad laminate and printed circuit board prepared using the same A resin composition is provided. The resin composition comprises the following components: (A) a halogen-free epoxy resin; (B) a hardener; and (C) a phosphorus-containing phenolic resin of the following formula (I): wherein m, n, l, R1, and R2 are as defined in the specification.
US11339257B2	Method of preparing chemically modified anion exchange membrane The present inventive concept relates to a chemically modified anion exchange membrane and a method of preparing the same and, more particularly, an anion exchange membrane in which sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane are substituted with anion conductive groups such as ammonium group, phosphonium group, imidazolium group, pyridinium group and sulfonium group, and a method of preparing an anion exchange membrane by chemically modifying sulfonic acid groups in a perfluorinated sulfonic acid electrolyte membrane.
US11339256B1	Dual cure composition A composition contains (a) a silicon-free mercapto compound comprising 2 or more mercapto groups; (b) a linear polyorganosiloxane containing one or more than one terminally unsaturated alkenyl group, 40 mole-percent or more phenyl groups relative to moles of silicon atoms and at least one alkoxysilyl group per molecule; (c) a resinous polyorganosiloxane containing one or more than one terminally unsaturated alkenyl group and 20 mole-percent or more phenyl groups relative to moles of silicon atoms; (d) a photoinitiator; and (e) a moisture cure catalyst; and wherein the molar ratio of mercapto groups to terminally unsaturated alkenyl groups in the composition is in a range of 0.3 to 2.0.
US11339255B2	Biodegradable textiles, masterbatches, and method of making biodegradable fibers A masterbatch is disclosed, along with associated methods, and biodegradable filaments, fibers, yarns and fabrics. The masterbatch includes 0.2 to 5 mass % CaCO3, an aliphatic polyester with a repeat unit having from two to six carbons in the chain between ester groups, with the proviso that the 2 to 6 carbons in the chain do not include side chain carbons, and a carrier polymer selected from the group consisting of PET, nylon, other thermoplastic polymers, and combinations thereof.
US11339251B2	Resin composition, resin film, laminate, multilayer printed wiring board and method for producing multilayer printed wiring board The present invention relates to a resin composition comprising a maleimide compound having a saturated or unsaturated divalent hydrocarbon group and a divalent group having at least two imido bonds; and a catalyst comprising at least one selected from the group consisting of an imidazole compound, a phosphorus compound, an azo compound and an organic peroxide.
US11339240B2	Conjugated diene-based polymer, branching agent, production method for conjugated diene-based polymer, extended conjugated diene-based polymer, rubber composition, and tire A conjugated diene-based polymer of the present invention has an absolute molecular weight measured by viscosity detector-equipped GPC-light scattering measurement, of 40×104 or more and 5000×104 or less, has a branching number (Bn) measured by the viscosity detector-equipped GPC-light scattering measurement, of 8 or more, and has a modification ratio of 60% by mass or more.
US11339237B2	Method of preparing thermoplastic resin, thermoplastic resin prepared therfrom and thermoplastic resin composition comprising the same The present invention relates to a method of preparing a thermoplastic resin, a thermoplastic resin prepared by the same, and a thermoplastic resin composition including the same. More specifically, the method of the present invention includes a step of performing acid coagulation of emulsion polymerization latex, a step of treating coagulated slurry with a base and performing dehydration, and a step of adding a metal salt and water to dehydrated wet powder to adjust pH to 9 or more. According to the present invention, the method may increase the productivity of a thermoplastic resin, and the thermoplastic resin prepared by the method has excellent mechanical strength, thermal stability, and appearance properties. In addition, when the thermoplastic resin of the present invention is used in coating, the thermoplastic resin has an effect of improving the adhesive strength and appearance quality of a coating film.
US11339233B2	Flame retardant poly(vinyl chloride) compounds Disclosed herein are plasticized poly(vinyl chloride) compounds. One aspect relates to a flame retardant poly(vinyl chloride) compound, comprising a mixture of poly(vinyl chloride); and a plasticizer comprising polymeric plasticizer, and/or alkyl aryl fire retardant plasticizer, wherein the mixture has a Limiting Oxygen Index of greater than 50% according to ASTM D2863; an Elongation at Break of at least 10% according to ASTM D638 (Type IV); and a Modulus of Elasticity of less than about 15,000 psi according to ASTM 638 (Type IV).
US11339232B2	Dispersion assistant for suspension polymerization and method for producing vinyl-based polymer using the same Provided is a dispersion assistant useful for suspension polymerization of vinyl-based compounds. The dispersion assistant comprises a polyvinyl alcohol-based polymer (A) comprising a constituent unit represented by the general formula (1) shown below at 0.1 to 10 mol % per polyvinyl alcohol monomer unit and having a saponification degree of 15 to 70 mol %. (In the formula, R denotes an alkyl group.)
US11339228B2	Dispersion powder composition containing vinyl alcohol copolymerisate Water-redispersible polymer powders with improved characteristics in building materials are prepared using a drying aid which is a polyvinyl alcohol copolymer also containing vinyl ester monomers and specific comonomers.
US11339227B2	Cyclodextrin polymer for fast absorption of organic pollutants dissolved in water Provided is a novel multifunctional cyclodextrin polymer capable of adsorbing the organic pollutants dissolved in water super-fast. A cyclodextrin polymer with a three-dimensional network structure and quaternary ammonium salt functional groups is obtained by mixing and crosslinking a cyclodextrin, a rigid crosslinking agent, a non-rigid crosslinking agent and a quaternary ammonium salt at certain temperature. The polymer is capable of adsorbing the organic pollutants dissolved in water at an ultra-fast rate, and the polymer after adsorption is easily regenerated and can be repeatedly used multiple times without causing a decrease in the adsorption property.
US11339226B2	Humanised ADAMTS13 binding antibodies The present invention further relates to specific humanised monoclonal antibodies inhibiting ADAMTS13 function. The present invention relates to methods of treatment by human ADAMTS13 inhibition in circulatory assist device induced haemorrhagic complication such as a bleeding disorder, in particular, bleeding after left ventricular assist device (LVAD) implantation.
US11339223B2	Methods of use of anti-Sortilin antibodies for treating a disease, disorder, or injury The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind on or more epitopes within a Sortilin protein, e.g., human Sortilin or a mammalian Sortilin, and use of such compostions in preventing, reducing risk, or treating an individual in need thereof.
US11339221B2	Bispecific antibody constructs and methods of use The present invention relates to bispecific antibody constructs that specifically bind both integrin alpha-V and integrin α5 (e.g., α5β1) and methods of making and using those constructs to treat cancer or other pathological conditions involving these integrins.
US11339215B2	Methods of treating cancer with human monoclonal antibodies against interleukin 8 (IL-8) Isolated human monoclonal antibodies which bind to IL-8 (e.g., human IL-8) are disclosed. The human antibodies can be produced in a hybridoma, transfectoma or in a non-human transgenic animal, e.g., a transgenic mouse, capable of producing multiple isotypes of human monoclonal antibodies by undergoing V-D-J recombination and isotype switching. Also disclosed are pharmaceutical compositions comprising the human antibodies, non-human transgenic animals, hybridomas, and transfectomas which produce the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
US11339214B2	Protein purification The present invention relates to a process for the purification of an antibody fragment from a periplasmic cell extract comprising a first cation exchange chromatography step and a second anion exchange chromatography step.
US11339212B2	α-synuclein protofibril-binding antibodies The present disclosure is based, in part, on the discovery of antibodies that selectively targets human α-synuclein aggregates such as oligomers/protofibrils, such as BAN0805. BAN0805 has a lower tendency to bind to the undesired monomeric α-synuclein target as compared to mouse monoclonal antibody mAb47.
US11339211B2	Nanobodies suitable for neuron regeneration therapy The invention is in the domain of delivery of molecules to brain cells across the blood-brain barrier. The invention relates to a novel polypeptide-based carrier that allows the efficient delivery of an effector peptide, to neuron cells across the blood-brain barrier, and to methods for the production and testing of such carrier, including a model for testing the capacity of such molecule to cross the blood-brain barrier and/or the toxicity of molecules on the blood brain barrier and/or the capacity of molecules that have crossed to target human brain cells (e/g. neurons, astrocytes and microglial cells).
US11339209B2	Compositions, methods, and therapeutic uses related to fusogenic protein minion The invention provides novel compositions, methods, and therapeutic uses related to fusogenic protein MINION (microprotein inducer of fusion).
US11339208B1	Camelidae single-domain antibodies against Yersinia pestis and methods of use Single-domain antibodies (SAbs) against three Yersinia pestis surface proteins (LcrV, YscF, and F1), nucleic acid sequences encoding the SAbs, and polypeptides comprising two or more SAbs capable of recognizing two or more epitopes and/or antigens. The present invention further includes methods for preventing or treating Y. pestis infections in a patient; methods for detecting and/or diagnosing Y. pestis infections; and devices and methods for identifying and/or detecting Y. pestis on a surface and/or in an environment.
US11339206B2	Compositions and methods for the treatment of immunodeficiency The present invention relates to compositions and methods for the treatment of immunodeficiency (e.g., primary immunodeficiency disease). In particular, the invention provides human plasma immunoglobulin compositions containing select antibody titers specific for a plurality of respiratory pathogens, methods of identifying human donors and donor samples for use in the compositions, methods of manufacturing the compositions, and methods of utilizing the compositions (e.g., for prophylactic administration and/or therapeutic treatment (e.g., passive immunization (e.g., immune-prophylaxis))).
US11339203B2	Antitumor peptide and use thereof The antitumor peptide provided by the present invention is a synthetic peptide including both of: (1) an amino acid sequence composing the second transmembrane region from the N-terminal of a membrane protein sphingosine 1-phosphate receptor 1 (S1PR1), or a modified amino acid sequence formed by deletion substitution or addition of 1, 2 or 3 amino acid residues in the amino acid sequence; and (2) an amino acid sequence functioning as a cell-penetrating peptide (CPP); wherein the total number of amino acid residues is 100 or less.
US11339201B2	Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof The present disclosure provides variant PD-L1 immunomodulatory polypeptides, and fusion polypeptides comprising the variant immunomodulatory peptides. The present disclosure provides T-cell modulatory multimeric polypeptides, and compositions comprising same, where the T-cell modulatory multimeric polypeptides comprise a variant immunomodulatory polypeptide of the present disclosure. The present disclosure provides nucleic acids comprising nucleotide sequences encoding the T-cell modulatory multimeric polypeptides, and host cells comprising the nucleic acids. The present disclosure provides methods of modulating the activity of a T cell; the methods comprise contacting the T cell with a T-cell modulatory multimeric polypeptide of the present disclosure.
US11339198B2	Codon optimized IL-15 and IL-15R-alpha genes for expression in mammalian cells The present invention provides for nucleic acids improved for the expression of interleukin-15 (IL-15) in mammalian cells. The invention further provides for methods of expressing IL-15 in mammalian cells by transfecting the cell with a nucleic acid sequence encoding an improved IL-15 sequence. The present invention further provides expression vectors, and IL-15 and IL 15 receptor alpha combinations (nucleic acid and protein) that increase IL-15 stability and potency in vitro and in vivo. The present methods are useful for the increased bioavailability and biological effects of IL-15 after DNA, RNA or protein administration in a subject (e.g. a mammal, a human).
US11339194B2	Truncated rotavirus VP4 protein and application thereof The invention relates to a truncated rotavirus VP4 protein, a sequence encoding the same, a method for preparing the same, and a pharmaceutical composition and a vaccine comprising the protein, wherein the protein, the pharmaceutical composition and the vaccine are useful for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea. The invention further relates to use of the protein in the manufacture of a pharmaceutical composition or a vaccine for preventing, alleviating or treating rotavirus infection and a disease caused by rotavirus infection, such as rotavirus gastroenteritis and diarrhea.
US11339191B2	Stapled peptides and uses thereof The present invention relates to peptidomimetic macrocycles comprising at least one macrocycle-forming linker and an amino acid sequence chosen from the group consisting of: i) an amino acid sequence with at least about 50%, 60%, 70%, 80%, 90%, or 95% sequence identity to a human sequence IRAK2 54-71 (SEQ ID No1) and 100% identity with the amino acids in the positions 5-6, 9-11, 14-15 or ii) an amino acid sequence with at least about 50%, 60%, 70, 80%, 90%, or 95% sequence identity to a human sequence IRAKM 66-83 (SEQ ID No2) and 100% identity with the amino acids in the positions 5-6, 9-11, 13-14, wherein the peptidomimetic macrocycle comprises an a-helix and at least two natural or two non-natural amino acids crosslinked by a macrocycle-forming linker. It also concerns method of preparation of said peptidomimetic macrocycles and uses thereof, pharmaceutical composition and uses thereof, in particular as inhibitors of inflammatory pathways.
US11339185B2	Cyclic dinucleotides as anticancer agents The present invention is directed to compounds of the formulae I, II and III as shown below wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.
US11339179B2	Preparation for natural product trabectedin The present invention provides a preparation method for a natural product Trabectedin. Specifically, the present invention provides a preparation method for Et-743. In the method, tyrosine is used as an initial substrate, and after 26 steps of reaction, the Et-743 is synthesized. Raw materials and agents used in the synthetic route can all easily be obtained, reaction conditions are relatively mild, and preparation in large scale can be implemented.
US11339171B2	MDM2 inhibitors A compound capable of being used as a tumor inhibitor, a preparation method therefor, and application thereof. The compound has a structure represented by general formula I; a stereoisomer, an enantiomer, a raceme, a cis/trans isomer, a tautomer, and an isotopic variant of the compound are comprised; the compound can be used separately or in combination with other drugs for treating tumors or inflammatory diseases, or for treating other disorders or diseases mediated by the activity of MDM2 and/or MDM4, and shows prominent curative activity.
US11339170B1	Spiropyrrolidine derived antiviral agents The present invention discloses compounds of Formula (I), and pharmaceutically acceptable salts, thereof: which inhibit coronavirus replication activity. The invention further relates to pharmaceutical compositions comprising a compound of Formula (I) or a pharmaceutically acceptable salt thereof, and methods of treating or preventing a coronavirus infection in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof.
US11339169B2	P2X3 and/or P2X2/3 compounds and methods The present disclosure provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R7 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient.
US11339167B2	Substituted piperidines as kinase inhibitors The present invention relates to a compound represented by the following Chemical Formula 1, or a pharmaceutically acceptable salt, stereoisomer, or tautomer thereof, and the compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions: wherein: R1 is pyrazolyl, isooxazolyl, isothiazolyl, phenyl, or benzothiazolyl, wherein the pyrazolyl, isoxazolyl, isothiazolyl, phenyl, or benzothiazolyl is optionally substituted with one Ra substituent; R2 is H, halogen, CN, or C1-5 alkyl; and Ra is C1-5 alkyl, C1-5 haloalkyl, C1-5 hydroxyalkyl, C3-6 cycloalkyl, tetrahydropyranyl, piperidinyl, or morpholino.
US11339156B2	3-(1H-pyrazol-4-yl)pyridine allosteric modulators of the M4 muscarinic acetylcholine receptor The present invention is directed to pyrazol-4-yl-pyridine compounds which are allosteric modulators of the M4 muscarinic acetylcholine receptor. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which M4 muscarinic acetylcholine receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.
US11339154B2	Heterocycle-substituted bicyclic azole pesticides Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N oxides, and salts thereof, wherein A, X1, X2, X3 and R2 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.
US11339152B2	Inhibitors The invention relates to a compound of formula (I): A-B-D-E (I) or a pharmaceutically acceptable salt, solvate or polymorph thereof, including all tautomers and stereoisomers thereof, wherein: A is selected from monocyclic and bicyclic heteroaryl, which may independently substituted by alkyl or amino; B is selected from alkyl, heteroalkyl, alkyl-amino, aryl, heteroaryl, cycloalkyl, heterocyclyl and alkylene, wherein said groups may independently be substituted by alkyl; D is selected from aryl-amino, heteroaryl-amino, cycloalkyl-amino, heterocyclyl, heterocyclyl-amino, urea, thioamide, thiourea, sulfonamide, sulfoximine and sulfamoyl, wherein said aryl, heteroaryl, cycloalkyl and heterocyclyl groups may independently be substituted; and E is selected from aryl, heteroaryl, cycloalkyl, heterocyclyl, wherein said aryl, heteroaryl, cycloalkyl and heterocyclyl groups may independently be substituted. The compounds of formula (I) are inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5). QC catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate residues into pyroglutamic acid under liberation of water.
US11339147B2	Lactam compound as FXR receptor agonist Disclosed is a compound as shown in formula (I), an optical isomer thereof or a pharmaceutically acceptable salt thereof, and the present invention relates to the use of same in the preparation of a drug for treating FXR-related diseases.
US11339145B2	Synthesis of cerdulatinib The present disclosure provides processes for the preparation of cerdulatinib, which is of formula I: or a salt thereof. The disclosure also provides intermediates and processes for the preparation of the intermediates useful in the preparation of cerdulatinib or a salt thereof.
US11339141B2	Methods and compounds for restoring mutant p53 function Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer. The present disclosure describes compounds and methods to recover wild-type function to p53 mutants. The compounds of the present invention can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA and activate downstream effectors involved in tumor suppression. The disclosed compounds can be used to reduce the progression of cancers that contain a p53 mutation.
US11339138B2	Process and intermediates for the preparation of certain nematicidal sulfonamides The present invention provides a method for preparing a compound of Formula C, Formula D, or Formula F: wherein each R1, R2, and R3 is independently H, SF5, N(C1-C8 alkyl)(C1-C8 alkyl), C(═S)N(C1-C8 alkyl)(C1-C8 alkyl), SO2N(C1-C8 alkyl)(C1-C8 alkyl), OSO2(C1-C8 alkyl), OSO2N(C1-C8 alkyl)(C1-C8 alkyl), N(C1-C8 alkyl)SO2(C1-C8 alkyl), or C1-C8 alkyl, C1-C8 haloalkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C10 cycloalkyl, C3-C10 halocycloalkyl, C4-C10 alkylcycloalkyl, C4-C10 cycloalkylalkyl, C6-C14 cycloalkylcycloalkyl, C5-C10 alkylcycloalkylalkyl, C3-C8 cycloalkenyl, C1-C8 alkoxy, C1-C8 haloalkoxy, C3-C8 cycloalkoxy, C3-C8 halocycloalkoxy, C4-C10 cycloalkylalkoxy, C2-C8 alkenyloxy, C2-C8 alkynyloxy, C1-C8 alkylthio, C1-C8 alkylsulfinyl, C1-C8 alkylsulfonyl, C3-C8 cycloalkylthio, C3-C8 cycloalkylsulfinyl, C3-C8 cycloalkylsulfonyl, C4-C10 cycloalkylalkylthio, C4-C10 cycloalkylalkylsulfinyl, C4-C10 cycloalkylalkylsulfonyl, C2-C8 alkenylthio, C2-C8 alkenylsulfinyl, C2-C8 alkenylsulfonyl, C2-C8 alkynylthio, C2-C8 alkynylsulfinyl, C2-C8 alkynylsulfonyl, or phenyl; or two of R1, R2, and R3 on adjacent ring atoms may be taken together to form a 5- to 7-membered carbocyclic or heterocyclic ring, each ring containing ring members selected from carbon atoms and up to 3 heteroatoms independently selected from up to 2 O, up to 2 S, and up to 3 N, wherein up to 2 carbon atom ring members are independently selected from C(═O) and C(═S) and such ring is optionally substituted with up to 3 substituents independently selected from the group consisting of C1-C4 alkyl, C1-C4 haloalkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl, C3-C7 cycloalkyl, C3-C7 halocycloalkyl, C4-C8 alkylcycloalkyl, C4-C8 haloalkylcycloalkyl, C4-C8 cycloalkylalkyl, C4-C8 halocycloalkylalkyl, C1-C8 alkoxy, C1-C8 haloalkoxy, C2-C8 alkoxycarbonyl, C2-C6 haloalkoxycarbonyl, C2-C6 alkylcarbonyl and C2-C6 haloalkylcarbonyl; and M is an inorganic cation or organic cation.
US11339132B2	Compound for organic electric element, organic electric element comprising the same, and electronic device thereof The present invention provides the compound represented by Formula 1, an organic electric element comprising a first electrode, a second electrode, and an organic material layer formed between the first electrode and the second electrode, and electronic device thereof, and by comprising the compound represented by Formula 1 in the organic material layer, the driving voltage of the organic electronic device can be lowered, and the luminous efficiency and life time of the organic electronic device can be improved.
US11339124B2	3-(benzylamino)-4-(cyclohexylamino)-n-(2-(piperazin-1-yl)ethyl)benzenesulfonamide derivatives and related ferrostatin-1 analogues as cell death inhibitors for treating e.g. stroke The present invention relates to 3-(benzylamino)-4-(cyclohexylamino)-N-(2-(piperazin-1-yl)ethyl)benzenesulfonamide derivatives and related ferrostatin-1 (Fer-1) analogues as cell death inhibitors by inhibition of ferroptosis and/or oxytosis for the treatment of stroke, myocardial infarction, diabetes, sepsis, the prevention of transplant rejection, neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, dementia with Lewy bodies and Friedreich's ataxia. The present invention further relates to pharmaceutical compositions of these compounds and discloses methods for making the compounds and the corresponding intermediate.
US11339121B2	Method of preparing diisocyanate composition In the embodiments, an aqueous hydrochloric acid solution instead of hydrogen chloride gas and solid triphosgene instead of phosgene gas may be used in the process of preparing a diisocyanate from a diamine through a diamine hydrochloride. In addition, the embodiments provide processes for preparing a diisocyanate composition and an optical lens, which are excellent in yield and quality with mitigated environmental problems by controlling the size of the diamine hydrochloride composition, the b* value according to the CIE color coordinate of the diamine hydrochloride composition, or the content of water in the diamine hydrochloride composition within a specific range.
US11339116B2	Reactive separation process to convert cyclic alkylene ureas into their corresponding alkylene amines A process to convert cyclic alkylene ureas into their corresponding alkylene amines is provided. An exemplary process includes reacting the cyclic alkylene ureas with an amine compound chosen from the group of primary amines or secondary amines that have a higher boiling point than the alkylene amines formed during the process, wherein the process is a reactive separation process and the reaction mixture contains less than about 10 wt % of water on the basis of total weight of the reaction mixture.
US11339113B2	Process for the preparation of cis-alpha,beta substituted cyclopentanones Described herein is a process for the preparation of a mixture of compounds of formula having a weight ratio of the cis-diastereomers to trans-diastereoisomers higher than 1:1, where R1 represents a C1-8 alkyl group, a C2-8 alkenyl group or a C2-8 alkynyl group, each optionally substituted with one or two of a C1-4 alkyl alkoxy ether group and/or a C1-4 alkyl carboxylester group and R2 represents a C1-6 alkyl, a C2-6 alkenyl or a C2-6 alkynyl group, each optionally substituted with a C1-4 alkyl alkoxy ether group, a carboxylic acid group or a C1-4 alkyl carboxylester group and compounds suitable in the process.
US11339106B2	Method for producing 1,2-dichloro-3,3-difluoro-1-propene and solvent composition By fluorinating 1,2,3,3-tetrachloro-1-propene (1230xd) using hydrogen fluoride as a fluorinating agent, an efficient method for producing 1,2-dichloro-3,3-difluoro-1-propene (1232xd) is provided. Through this composition including 1232xd, there are also provided an environmentally friendly composition having excellent ability to dissolve various organic matters, a method for cleaning an article using the composition, a method for producing a lubricant solution using the composition, and a method for producing a component provided with a lubricant coating film.
US11339105B2	Methods for operating dehydrogenation processes during non-normal operating conditions According to one or more embodiments disclosed herein, methods for operating dehydrogenation processes during non-normal operating conditions, such as at start-up, shut-down, system recycle, or unit trip, are described. The methods may include contacting a feed stream with a catalyst in a reactor portion of a reactor system to form a reactor effluent stream, separating at least a portion of the reactor effluent stream from the catalyst, passing the catalyst to a catalyst processing portion and processing the catalyst, wherein processing the catalyst comprises contacting the catalyst with oxygen, passing the catalyst from the processing portion to the reactor portion, wherein the catalyst exiting the processing portion comprises at least 0.001 wt. % oxygen, and contacting the catalyst with supplemental hydrogen, the contacting removing at least a portion of the oxygen from the catalyst by a combustion reaction.
US11339104B2	Process for upgrading natural gas liquids from shale gas without front-end demethanizer Processes and systems for upgrading natural gas liquids. At least a portion of the natural gas liquid components in a shale gas stream can be dehydrogenated to their corresponding olefin derivatives prior to separating any methane from the liquids. Further processing subsequent to dehydrogenation could include various separations, oligomerizing olefins produced in the dehydrogenation step, recovering desired products, etc. The order of the processing steps subsequent to dehydrogenation could be adjusted in various cases.
US11339097B2	Refractory metal silicide nanoparticle ceramics Particles of a refractory metal or a refractory-metal compound capable of decomposing or reacting into refractory-metal nanoparticles, elemental silicon, and an organic compound having a char yield of at least 60% by weight are combined to form a precursor mixture. The mixture is heating, forming a thermoset and/or metal nanoparticles. Further heating form a composition having nanoparticles of a refractory-metal silicide and a carbonaceous matrix. The composition is not in the form of a powder
US11339092B2	Non-flowable quick-setting phosphate cement repair material with strong cohesive forces and preparation method thereof The present invention belongs to the field of composite materials, and particularly to a non-flowable quick-setting phosphate cement repair material with strong cohesive forces and the preparation method thereof. The material comprises the following raw materials in percentage by weight: 20% to 40% of sand, 5% to 12% of ammonium dihydrogen phosphate, 10% to 25% of magnesium oxide, 2% to 8% of fly ash, 30% to 60% of rubber powder, 6% to 10% of silica fume, 0.35% to 0.6% of a polycarboxylate high efficiency water-reducing agent, 1% to 5% of sodium silicate, 1.5% to 2% of a polypropylene fiber, 0.5% to 2% of a retarder, and 8% to 10% of water. The material is used as the repair material for the special positions of bottom boards of bridges or facades of buildings which are damaged, and the repair effect thereof is remarkable.
US11339088B2	Fracture resistant stress profiles in glasses Glass-based articles comprise stress profiles providing improved fracture resistance. The glass-based articles herein provide high fracture resistance after multiple drops.
US11339087B2	Antiglare glass substrate An antiglare glass substrate includes a glass substrate having a first main surface and a second main surface that is opposite to the first main surface. The first main surface has undergone an antiglare treatment and a fluorine-containing organosilicon compound coating film as an antifouling film is laminated thereon. The first main surface partly includes a non-antiglare-treated portion that has not undergone the antiglare treatment. The non-antiglare-treated portion has a surface roughness Ra of less than 10 nm. A difference in height along a plate thickness direction of the glass substrate between the antiglare-treated portion that has undergone the antiglare treatment and the non-antiglare-treated portion is 10 μm or larger and 200 μm or less.
US11339086B2	Coating composition and cooking appliance A coating composition includes phosphorus pentoxide (P2O5), aluminum oxide (Al2O3), boron trioxide (B2O3), zinc oxide (ZnO), I group-based metal oxide, and II group-based metal oxide. The coating composition includes by weight based on a total weight of the coating composition 35 to 55% P2O5, 5 to 35% Al2O3, 5 to 40% I group-based metal oxide, 5 to 10% B2O3, 1 to 5% ZnO, and 1 to 10% II group-based metal oxide.
US11339085B2	Glass fiber composition, glass fiber and composite material thereof A composition for producing a glass fiber, including the following components with corresponding percentage amounts by weight: SiO2: 57.4-60.9%; Al2O3: greater than 17% and less than or equal to 19.8%; MgO: greater than 9% and less than or equal to 12.8%; CaO: 6.4-11.8%; SrO: 0-1.6%; Na2O+K2O: 0.1-1.1%; Fe2O3: 0.05-1%; TiO2: lower than 0.8%; and SiO2+Al2O3: lower than or equal to 79.4%. The total weight percentage of the above components in the composition is greater than 99%. The weight percentage ratio of Al2O3+MgO to SiO2 is between 0.43 and 0.56, and the weight percentage ratio of CaO+MgO to SiO2+Al2O3 is greater than 0.205. The composition can significantly increase the glass modulus, effectively reduce the glass crystallization rate, secure a desirable temperature range (ΔT) for fiber formation and enhance the refinement of molten glass, thus making it particularly suitable for high performance glass fiber production with refractory-lined furnaces.
US11339084B2	Fusion formable and steam strengthenable glass compositions with platinum compatibility Glass-based articles that include a compressive stress layer extending from a surface of the glass-based article to a depth of compression are formed by exposing glass-based substrates to water vapor containing environments. The glass-based substrates have compositions selected to be fusion formable, to be steam strengthen able, and to avoid the formation of platinum defects during the forming process. The methods of forming the glass-based articles may include elevated pressures and/or multiple exposures to water vapor containing environments.
US11339076B2	Preparation of carbon-doped silicon dioxide granulate as an intermediate in the preparation of quartz glass One aspect relates to a process for the preparation of a quartz glass body. The process includes providing a silicon dioxide granulate I prepared from a pyrogenically produced silicon dioxide powder, treating the silicon dioxide granulate I with a reactant at a temperature in a range from 1000 to 1300° C., and making a glass melt out of the silicon dioxide granulate. A quartz glass body is made out of at least a part of the glass melt. Furthermore, one aspect relates to a quartz glass body obtainable by this process. Furthermore, one aspect relates to a light guide, an illuminant, and a formed body, each of which is obtainable by further processing of the quartz glass body. One aspect additionally relates to a process for the preparation of a silicon dioxide granulate II.
US11339071B2	Process for treating sewage sludge An apparatus, method and system is provided for treating sewage sludge by dewatering the sewage sludge, heating the sewage sludge being treated to destroy pathogens, and then reducing volatile solids in the sewage sludge being treated through biochemical decomposition to produce a treated biosolids product that meets government regulations for pathogen reduction and vector attraction reduction.
US11339068B2	Eductor-based membrane bioreactor A process for treating domestic wastewater may include directing wastewater into a tank containing a membrane filter and mixed liquor. The process may include recirculating wastewater and mixed liquor from a top end of the tank into a bottom end of the tank via a recirculation conduit. The process may include introducing a flow of wastewater and mixed liquor from the recirculation conduit into an aeration device and drawing ambient air into the aeration device using the flow of wastewater and mixed liquor from the recirculation conduit. The process may also include drawing wastewater and mixed liquor proximately surrounding the aeration device into the aeration device using the flow of wastewater and mixed liquor from the recirculation conduit. The process may include aerating a mixture of wastewater and mixed liquor with the ambient air below the membrane filter.
US11339065B2	Apparatus for producing aqueous pH- and redox potential-adjusting solution An apparatus has a platinum group metal carrying resin column provided in a supply line of ultrapure water, and has a pH adjuster injection device and a redox potential adjuster injection device provided in a later stage thereof. The apparatus has a membrane-type deaeration apparatus and a gas dissolving membrane apparatus sequentially provided in a later stage of the devices, and a discharge line communicates with the gas dissolving membrane apparatus. A pH meter and an ORP meter are each provided at some midpoint in the discharge line, and the pH meter and the ORP meter are connected to a control device. Then, the control device controls the amount of adjusters to be injected from the pH adjuster injection device and the redox potential adjuster injection device, on the basis of the measurement results of the pH meter and the ORP meter.
US11339062B2	Methods for sustainable membrane distillation concentration of hyper saline streams A novel method of producing concentrated streams or otherwise useful hypersaline brines from a source of non-potable or otherwise impaired water is provided. The method comprises feeding the source water into the feed side of a membrane distillation unit while simultaneously feeding a distillate stream through the receiving side of the distillation unit. The feed and receiving sides are separated by a hydrophobic, microporous membrane that allows water vapor to flux through the membrane to the receiving side. As the membrane becomes clogged with particulates, the unit can be subjected to stream flow reversal and/or temperature gradient reversal in order to remove those particulates and restore previous vapor flux levels, after which previous operations can be resumed.
US11339061B2	Solar water pasteurizer A solar water pasteurizer has a water jug removably disposed in a solar box with insulation and a solar window. The water jug has a lid to close an aperture in the solar box and a handle thermally isolated from the water jug to facilitate handling of the water jug with heated water. Multiple water jugs can be swapped in and out of the solar box. The solar box also has a thermal mass to preserve some heat in the solar box.
US11339060B2	Retrofit bottle filtration device An apparatus provides a water bottle mouthpiece attachment which can filter microplastics and other contaminant substances from bottles, particularly disposable plastic water bottles. The filter of the apparatus includes a filter housing that is attached to a cap that fits inside a common plastic bottle. Soft rubber rings, tapering from to radially larger on the top to radially smaller on the bottom in a generally conical fashion, ensure a watertight fit to the inside opening of any drinking bottle. A friction closing/opening spout at the top of the filter enables selective opening of the bottle and prevents accidental spillage of bottle contents. The filter housing is also offset from the center, giving space to an air valve that allows air to enter the bottle without disturbing the flow of water from the bottle, thus providing optimal lamellar flow without allowing fluid to escape through the air valve during consumption.
US11339053B2	Nitride crystal An object of the present invention is to improve quality of a nitride crystal, and also improve performance and manufacturing yield of a semiconductor device manufactured using the crystal. Provided is a nitride crystal in which a composition formula is represented by InxAlyGa1-x-yN (satisfying 0≤x≤1, 0≤y≤1, 0≤x+y≤1), and the concentration of B in the crystal is less than 1×1015 at/cm3, and each of the concentrations of O and C in the crystal is less than 1×1015 at/cm3 in a region of 60% or more of a main surface.
US11339048B2	Fleet fuel management system A fleet fueling system may be implemented with controllers electronically interfacing with fuel dispensers at dispensing stations and communicating via a wide area network with one or more computing device implementing multiple subsystems. Hardware components and subsystems may be configured to avoid operating errors and provide end-to-end functionality, including one or more of: avoiding damage to movable readers that can collect information about assets positioned at fuel dispensing stations, selectively authorizing fuel to be dispensed based on the types and amount of fuel those assets are authorized to receive, quickly and reliably entering information about assets, providing analytics relating to fuel usage per asset, predicting future fuel needs at each of multiple fuel dispensing sites and scheduling fuel deliveries based on predicted needs, and detecting or correcting operating errors in the system.
US11339046B1	Auto-water shut-off for an external door water dispenser A refrigerator including a refrigerated compartment and a door to open and close at least a portion of the refrigerated compartment. A dispenser unit is positioned on the door that is configured to dispense content into a receptacle. The dispenser unit includes a receptacle support, a dispensing system, a sensor system with at least a first sensor and a second sensor. A control unit electrically coupled to the dispensing system and sensor system. The dispensing system is configured to operate the first sensor to determine the receptacle height and the second sensor to determine the liquid height within the receptacle. The control unit determines when to stop filling the receptacle based on the two measurements. A method for detecting when to shut off the dispensing unit when dispensing liquid into a receptacle.
US11339044B1	Wine taking device used in wine fresh-keeping device A wine taking device used in a wine fresh-keeping device may be shown and described. A first pipe, the first end of the first pipe is connected with the fresh-keeping gas storage tank, a first solenoid valve, a first end of the first solenoid valve is connected to a second end of the first pipe, a second pipe, the first end of the second pipe is connected to a second end of the first solenoid valve, a three-way valve, a first end of the three-way valve is connected to a second end of the second pipe, a second solenoid valve, a first end of the second solenoid valve is connected to a second end of the three-way valve, and a second end of the second solenoid valve is provided with a hollow needle used to reach into the wine bottle to take wine, and connected to the second solenoid valve.
US11339043B1	Wine fresh-keeping device A wine fresh-keeping device may be shown and described. The wine fresh-keeping device includes: a housing, and an exchange port for exchanging items inside and outside the housing, and a sealing cover is provided at the exchange port, a containing chamber is formed inside the housing, a fresh-keeping gas storage tank, and one end of the fresh-keeping gas storage tank is matched with the exchange port, a wine bottle installation chamber, the wine bottle installation chamber is arranged in the containing chamber, and one end of the wine bottle installation chamber is matched with the exchange port, a wine taking device, the wine taking device is arranged in the housing and connected to the fresh-keeping gas storage tank, and a refrigeration device, the refrigeration device is arranged on the housing, and cools the wine installation chamber.
US11339034B2	Coupling for suspended load control apparatus, system, and method Systems, apparatuses, and methods for a load control system for use on or with respect to a main load bearing line, carrier hook, and or head block of a crane, wherein the load control system may maintain tension on the load via a winch control line and a winch, wherein the tension may allow improved control over the load by the load control system.
US11339033B2	Wind turbine lifting arrangement Provided is a lifting arrangement configured to facilitate alignment of a load with a wind turbine assembly. The lifting arrangement includes a crane arrangement for hoisting the load to the wind turbine assembly, a tagline arrangement for stabilizing the load during a lifting manoeuvre, a sensor arrangement configured to detect a motion of the wind turbine assembly relative to the load during the lifting manoeuvre, an actuator arrangement for adjusting the position of the load relative to the wind turbine assembly, and a control arrangement for controlling actuators of the actuator arrangement to reduce the detected relative motion. Also provided is a method of aligning a load with a wind turbine assembly.
US11339032B2	Structure installation system with vehicle having hangers to support a wall A structure installation system which maintains one or more walls in a desired position and orientation during installation of the one or more walls. The structure installation system generally includes a vehicle which is adapted to traverse a ground surface. The vehicle includes an arm having an arm coupler to which a support is connected. One or more walls adapted to be installed in the ground surface may be removably connected to the support, such as by securing the walls to adjustable hangers that are removably connected to the support. By adjusting the positioning of the hangers, the orientation and position of the walls may be adjusted. Once put in position, the vehicle and support will retain the walls in the desired position and orientation while concrete is poured and allowed to cure to form a unitary structure such as a bollard wall.
US11339023B2	Image forming apparatus An image forming apparatus includes a cutting part cutting a medium, a transfer part arranged on a downstream side of the cutting part in a carrying direction and transfers a developer image to the medium; a flexure forming part having a guide part and forms a flexure of the medium by bending the medium between the cutting part and the transfer part in the carrying direction; and an opposing part that is arranged opposing the flexure forming part via a carrying path through which the medium is carried, wherein the guide part performs a retreat movement either before or after the cutting part starts to cut the medium, wherein the retreat movement is a movement of the guide part in which the guide part moves in a direction away from the opposing part.
US11339016B2	Sheet feeding device and image forming apparatus incorporating the sheet feeding device A sheet feeding device includes a contact member and a lock member. The contact member is configured to rotate from a retracted position to a contact position while a sliding portion of the lock member is sliding on a sliding target portion of the contact member and to rotate to the contact position to release the sliding portion of the lock member from the sliding target portion of the contact member. The lock member is configured to rotate between a locked position and a lock released position by a lock biasing force when the lock member moves in a lock direction of the lock member from the lock released position toward the locked position. The contact member has the lock target body and the sliding target portion at different positions from each other in a rotation center axial direction of the contact member.
US11339013B2	Medium feeding apparatus A medium feeding apparatus includes a medium mounting section, a movable edge guide that guides both edges of the medium mounted on the medium mounting section and has a first edge guide and a second edge guide, a feeding section, and a width adjuster configured to adjust a guide width depending on the medium. The width adjuster includes a first adjuster having a first holding section and a first guiding section, and the second adjuster having a second holding section and a second guiding section. The first holding section holds a part of the first edge guide, the first guiding section guides the edge of the medium between the first edge guide and the second guiding section, the second holding section holds a part of the second edge guide, and the second guiding section guides the edge of the medium between the second edge guide and the first guiding section.
US11339010B2	Swirl-flow forming body A swirl-flow forming body includes a through-hole; a jetting port that is formed on an inner periphery facing the through-hole; a fluid passage that allows fluid to be discharged into the through-hole via the jetting port so as to form a swirl flow that generates negative pressure for applying suction to a target object; and a flange portion that is formed so as to protrude from the inner periphery, the flange portion allowing passage of fluid to which suction is applied by the negative pressure while preventing the fluid discharged via the jetting port from flowing out of the through-hole towards the target object. The inner periphery is formed so as to guide the fluid discharged via the jetting port, in a direction away from the target object, to be discharged from the through-hole.
US11339007B2	Switch device The present disclosure relates to a switch device for a transfer point between a first and a second rotatable star wheel, at which transfer point objects can be selectively transferred from the first star wheel to the second star wheel, comprising a two-walled first switch element, the first and second walls of which extend around the transfer point such that a passage for the objects is formed therebetween; a second and a third switch element, which are arranged and held such that they each form extensions of the first and second wall, respectively, of the first switch element in the first position and the second position of the first switch element; and a transition device, which is designed to carry out the transition of the first to third switch elements.
US11339004B2	Movable material processing apparatus comprising a foldable conveyor A movable material processing apparatus for handling material such as ore, gravel, rock or the like, that includes: a foldable conveyor for discharging material from the apparatus. The foldable conveyor is movable between a transport position and an operating position. The foldable conveyor includes a loading block arranged at the loading end, and a discharge block extending from the loading block towards a discharge end. The discharge block is pivotally coupled to the loading block along a first axis being perpendicular to a transport path of the foldable conveyor and parallel with a carrying surface of the foldable conveyor. The loading block is pivotally coupled to a support structure of the movable material processing apparatus along a second axis being parallel to the transport path.
US11339000B1	Method and system for stocking and assembling SKUs A method and system for stocking and assembling SKUs includes stocking SKUs out of a lane, from the back of a downward slanting shelf, unit by unit, in long, narrow, single files separated by dividers, and with supplementary storage space available nearby. In addition it includes picking SKUs for multiple orders simultaneously off of shelves and onto a conveyor, registering all SKUs riding on the conveyor, and sorting and packing SKUs upon receiving notifications to do so as they ride on the conveyor. All coordinated such that after being brought to the stocking lane or supplementary storage space, SKUs are stocked into the shelves, picked off of the shelves and onto the conveyor, and then registered as riding on the conveyor, at which point timed notifications lead SKUs riding on the conveyor to be sorted and packed into orders which are then confirmed as being complete.
US11338997B2	Transport vehicle and transport facility A transport vehicle (2) is provided with: a support region (22) where a container (W) is supported; a container transfer apparatus (24) that inserts/takes a container (W) into/out of a container shelf; a recognition apparatus (27) that recognizes at least one of an article stored in a container (W) in a first state in which the container (W) is supported in the support region (22) and an article stored in a container (W) in a second state in which the container (W) is supported by the container transfer apparatus (24); and an article transfer apparatus (26) that transfers an article recognized by the recognition apparatus (27) between a container (W) in the first state and a container (W) in the second state.
US11338993B2	Discharging element for discharging substances into a liquid A discharging element for discharging substances into a liquid is disclosed, wherein the discharging element is in the form of a capsule, wherein the capsule casing (1-3) encloses a fillable volume for substances to be discharged, the capsule casing is made of a liquid-tight material and has at least one first opening (7) and at least one second opening (8) which are arranged in such a way that, when liquid flows around the capsule, a greater flow velocity is present at a first opening (7) than at a second opening (8), wherein the first and second opening are connected to one another via the fillable volume, and wherein either the first opening (7) and the second opening (8) are located on one outer surface, or wherein the surface normal of the capsule casing (1-3) at the location of the first opening (7) encloses an angle with the surface normal of the capsule casing at the location of the second opening (8).
US11338991B2	Fluid dispensing device The invention pertains generally to an improved fluid dispensing device, particularly a dispensing device which employs at least one hemispherical domed cannister source of reactants and which uses a color-changing dispensing plastic tip to inform the end-user if the reactants are at a proper use temperature.
US11338988B2	Dispensing pump and manufacturing method thereof A dispensing pump mechanism is provided. The pump comprises integrally molded temper-evidence part between a container collar and a spout; said collar has multiple off-centre outlet channel for dispensing one or more products from the container; said collar also comprises an integrated air vent to be blocked and opened by the rotation of the spout. The whole pump can be over-molded one-piece structure with elastic parts as being actuating parts. The pump improves the functions of the pump, such as lower restitution rate, less structural parts, lower cost, water/dust proof, lightweight, easy assembly.
US11338985B2	Repulpable container insulation products and methods of making and using same Container insulation including a batt comprised of large paper particles, at least 90% of which by weight are greater than 10 mm in diameter. Less than 5% by weight binder fibers are used, which have a length of at least 20 mm. Most preferably, no binder fibers are used. Where the batts are faced with paper, the paper is coated with a biodegradable coating. The resulting product is repulpable and recyclable in accordance with Fiber Box Association (FBA) testing protocols.
US11338984B2	Container for packaging a first fluid comprising a capsule for packaging a second fluid, and a capsule suitable for said container The subject matter described herein includes a container having a substantially tubular body forming a first volume for receiving a first fluid. The body includes a first and a second end, and the first end includes a dispenser provided with an aperture making it possible to dispense the contents of the container. The second end includes a closure element having a flexible wall making it possible for the flexible wall to be displaced between a first and a second position relative to the dispenser in order to thus dispense the contents of the container. The container includes a capsule with an outer wall forming a second volume for containing a second fluid. The capsule is positioned between the dispenser and the flexible wall respectively. The capsule is suitable for releasing the second fluid into the first volume during or after a first displacement of the flexible wall from its first position towards its second position.
US11338983B2	Oxygen scavenging compositions, articles containing same, and methods of their use The disclosure relates to oxygen scavenging compositions, methods of making the compositions, articles prepared from the compositions, and methods of making the articles. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
US11338982B2	Packaging part for securing an item to be packed in an outer packaging A packaging part (1) for securing an item to be packaged in an outer packaging, has at least one supporting body (2, 16) that acts as a decoupling element. The supporting body is formed as a hollow body and projects from a bearing base. The supporting body (2, 16) has a base with a relatively large cross-section in the area of the bearing base and tapers in a direction away from the bearing base. The supporting body (2, 16) further has in its shell surface at least one line of weakness (14) that divides the supporting body into an upper part and a lower part. The upper part of the supporting body (2, 16) can be pressed along the line of weakness (14), preferably completely, into the lower part under load.
US11338980B2	Shaped flexible shipping package and method of making A shipping package having a flexible inner sheet having a first surface and a second surface. The package has an article reservoir for accepting an article to be shipped and one or more expansion chambers. The expansion chambers can be inflated or otherwise expanded to provide structure to the package and to protect the article in the article reservoir.
US11338977B2	Flexible packaging structure with a built-in opening and reclose feature The invention comprises, in an embodiment, a resealable packaging structure comprising a container having a bottom and at least one sidewall extending upwardly therefrom, wherein the sidewall terminates in a flange. A flexible resealable lid is sealed to the flange. The lid comprises a polyethylene terephthalate layer disposed adjacent the flange, a pressure sensitive adhesive layer disposed adjacent the polyethylene terephthalate layer, and an oriented polypropylene layer disposed adjacent the pressure sensitive adhesive layer. The polyethylene terephthalate layer comprises a laser scored line which penetrates through the thickness of the inner layer but not through the outer layer and defines an opening portion that can be lifted out of the plane of the inner layer, thereby creating an opening through the lid defined by the laser score line.
US11338973B2	Binding tool A binding tool includes: a flexible strip-shaped belt; a head connected to a base end of the belt and including a through hole through which the belt wound around an object is inserted; a plurality of ratchet teeth protruding from a front surface of the belt at positions spaced apart in an extension direction; and a plurality of ratchet claws locking the plurality of ratchet teeth inserted through the through hole, wherein the head has, on one side in a width direction, a slit through which the belt can be inserted or removed, and the plurality of ratchet teeth and ratchet claws are inclined such that each of one end portions thereof on the one side in the width direction is on a downstream side of the extension direction as compared with each of the other end portions thereof on the other side in the width direction.
US11338972B2	Drinking vessel storage container combinations A drinking vessel storage container combination is provided herein. The combination comprises: a first body; a first cap demountably coupled to the first body; and a storage container demountably coupled to the first body opposite the first cap. The first cap comprises a lid, a port, and a strainer. The storage container comprises a second body, a second cap, a panel, and an insert. The first body is hollow, open-faced, and substantially cylindrical in shape. The bottom face is configured to allow the storage container to be demountable affixed thereto. The strainer is positioned adjacent to the port and within the chamber when the first cap is demountably affixed to the first body. The insert is selectively positioned within the second body. The panel is selectively positioned on top of the insert. The second cap is demountably affixed to the second body and the bottom face.
US11338970B2	Closure assembly A closure assembly comprising a two-part closure having a metal panel or disc (2) and a ring (3), and a container such as a glass jar (20). The ring (3) is substantially cylindrical with an axially upwardly extending sidewall and has a radially inwardly extending lower edge. The jar (20) terminates in a radially outwardly extending beaded rim (16) and the disc (2) has a curled circumference (8) such that this curl (8) co-operates with the beaded rim (16) of the container to provide a primary seal. In one example, in a metal ring (3), the lower edge is curled with equally spaced lugs (13) on the skirt wall. In a plastic ring, the upper rim feature may be omitted.
US11338966B2	Disposable container A disposable container is disclosed that includes a lid, a frontward facing sidewall portion, a rearward facing sidewall portion that is opposite the frontward facing sidewall portion, a first foldable sidewall portion, a second foldable sidewall portion that is opposite the first foldable sidewall portion, a pedal, wherein the pedal is rotatably coupled to the frontward facing portion, a hinge mechanism, wherein the hinge mechanism is rotatably coupled to the lid and the rearward facing sidewall portion, and two or more lines that each have a first line end and a second line end, wherein the first line end of each of the two or more lines is coupled to the pedal and the second line end of each of the two or more lines is coupled to the hinge mechanism.
US11338964B2	Unit for bonding a container, especially a pressurised beverage container, with the lid, and a preform for producing the container A unit for bonding the container with the lid, made of plastic, designated especially for pressurised beverages, having a profiled rim of the container opening and a profiled rim of the lid, characterised in that the profiled rim of the opening (2) of the container (1) comprises a flange (3) formed around the said opening (2), extending outwards away from the side wall of the container, where the flange (3) has a top surface (4), side surface (5) and bottom surface (6) bonded to the external side surface of the container (1), and where formed on the top surface (4) around the opening (2) of the container (1) there is a rib (7) protruding above the surface (4), while the profiled rim of the lid (8) comprises a groove (9) formed on the bottom surface (10) of the lid (8) around its bottom edge, the groove (9) accommodating the said rib (7) which supports the lid (8) without touching on the top surface (4) of the flange (3), where there is an energy director (12, 13) formed on the bottom of the groove (9) or the top surface of the rib (7), which focuses ultrasonic energy in the process of ultrasonic welding of the rib (7) and the lid (8).
US11338958B2	Convertible pallet with selectively actuated rolling feature A convertible pallet assembly, and associated method of making the convertible pallet, includes a first, planar pallet surface, and a second, planar support surface spaced therefrom. First and second sidewalls extend in parallel relation between the pallet surface and the support surface from adjacent opposite sides thereof. The sidewalls include first and second wheels with respective rotational axes that extend perpendicular to the sidewalls. An actuation mechanism is associated with each sidewall. The actuation mechanism has (i) a first position that allows the first and second wheels on one side to move upwardly and downwardly relative to the sidewall in a non-load carrying condition, and (ii) a second position such that the first and second wheels on the one side project outwardly from the support surface in a load carrying condition whereby the assembly can be rolled on the wheels as a cart.
US11338950B2	Inspection device, PTP packaging machine and PTP sheet manufacturing method An inspection device includes: an irradiator that irradiates an object with near-infrared light; a spectroscope that has a slit where reflected light enters and that disperses the reflected light into wavelength component lights; an imaging device that comprises an imaging element that takes a spectroscopic image of the wavelength component lights; and a processor that: obtains spectral data based on the spectroscopic image; and detects a type of the object using a predetermined analysis based on the spectral data. Each of the wavelength component lights is a single wavelength light, the inspection device satisfies L≥2P, where L is a width of each of the wavelength component lights in a wavelength dispersion direction on a light receiving surface of the imaging element and P is a width of a pixel in the wavelength dispersion direction on the light receiving surface.
US11338948B2	Progressive rate case cushion A drop packing apparatus for accepting one or more articles into a case, the drop packaging apparatus including a case pad for accommodating the case and a progressive rate linkage connected with respect to the case pad. A shock absorber is connected with respect to the progressive rate linkage. A conveyor 90 or similar device is connected with respect to the drop packing apparatus to provide a stream of articles to the case.
US11338946B2	Machine for packaging with at least one sterilization packaging material A machine for packaging an object with a sterilization packaging material the machine comprising: a plate configured to receive the sterilization packaging material and the object to be packaged placed on top, a gripping tool configured to grasp hold of a corner of the sterilization packaging material The gripping tool and the plate being are able to move relative to one another so as to allow the gripping tool to bring the corner over the top of the object and thus form a fold covering the object.
US11338945B2	Mixing-dosage apparatus for rotary packaging machines A mixing-dosage apparatus for rotary machines for packaging containers includes a mixing portion and a dosage portion. The two portions have a selective fluid connection using a flow control valve, which acts between the two portions so as to feed the dosage duct with consecutive loads of mixed food mass. Each load has a volume that is approximately equal to the volume of the mixing chamber.
US11338935B1	Automated flight control functional testing An automated flight control functional testing system includes a first sensor on a pilot input device for sensing position of the pilot input device, and a distributed network of sensors on a plurality of control surfaces of an aircraft for sensing positions of the control surfaces. A controller determines an expected position of each control surface based on data signals received from the first sensor, and the controller determines an actual position of each control surface based on data signals received from the distributed network of sensors. An automated flight control functional testing method includes transmitting angle information to a controller from a first angle sensor on a pilot input device and a second angle sensor on a control surface of an aircraft, and comparing an expected angle of a control surface based on the first sensor with an actual angle of the control surface based on the second sensor.
US11338932B1	Adjustable unmanned aerial vehicles with adjustable body portions This disclosure describes an unmanned aerial vehicle that may be configured during flight to optimize for agility or efficiency.
US11338930B2	Aircraft engine nacelle A nacelle of an aircraft turbofan engine including an air inlet upstream from the engine, a median section configured to surround a fan of the engine and delimited on the outside by a fan cowl supported by a fan housing to which it is attached at the upstream portion, a downstream section delimiting an annular flow path in which the air is configured to flow and housing thrust reversal devices, the thrust reversal approach including a movable cowl associated with at least one actuator for moving the movable cowl between a direct jet position, in which it provides the aerodynamic continuity of the nacelle and an indirect jet position in which it opens up a passage in the nacelle by uncovering cascade vanes arranged around this flow path that receive the cold air flow to return it towards the outside and forwards, the cascade vanes being attached to the movable cowl.
US11338926B2	Aircraft with electric propulsor A propulsor includes an electric motor, a fan unit, and a thrust system positioned downstream of and coupled to the fan unit. The electric motor converts electrical power to mechanical rotation to rotationally drive the fan unit and create an air stream directed towards the thrust control system.
US11338924B2	Hydraulic thrust vector yaw control for rocket catapult motor assembly A motor cap assembly for an ejection seat may comprise a servo valve assembly, a reservoir a cylinder, a motor cap manifold housing comprising a monolithic body having an internal manifold structure integral to the body configured to communicate a gas between a pressure source and a gas block, and configured to communicate a hydraulic fluid between, the reservoir, the servo valve assembly, and the cylinder, a rack piston disposed within the cylinder and configured to translate axially therein between a base end and a head end of the cylinder, and a motor cap outer housing coupled circumferentially about the motor cap manifold housing, wherein the motor cap outer housing is configured to rotate circumferentially about the motor cap manifold housing in response to an axial translation of the rack piston.
US11338923B2	Parachute control system for an unmanned aerial vehicle Disclosed is a technique for landing a drone using a parachute. The technique includes a parachute deployment system (PDS) that can deploy a parachute installed in a drone and land the drone safely. The parachute may be deployed automatically, e.g., in response to a variety of failures such as a free fall, or manually from a base unit operated by a remote user. For example, the PDS can determine the failure of the drone based on data obtained from an accelerometer, a gyroscope, a magnetometer and a barometer of the drone and automatically deploy the parachute if any failure is determined. In another example, the remote user can “kill” the drone, that is, cut off the power supply to the drone and deploy the parachute by activating an onboard “kill” switch from the base unit.
US11338920B2	Method for guiding autonomously movable machine by means of optical communication device A method for guiding an autonomously movable machine by means of an optical communication device having associated identification, location and orientation information. The method includes: receiving location information of a destination to which the autonomously movable machine travels, where the location information of the destination is determined by scanning and identifying, at the destination, at least one optical communication device around the destination; scanning and identifying the at least one optical communication device around the autonomously movable machine by means of the camera mounted on the autonomously movable machine, so as to determine location information of the autonomously movable machine; and on the basis of the location information of the destination and the location information of the autonomously movable machine, determining the relative location relationship between the autonomously movable machine and the destination, and controlling the autonomously movable machine or a part thereof to travel to the destination.
US11338919B2	Gimbal, frame, and unmanned aerial vehicle Embodiments of the present disclosure provides a gimbal. The gimbal includes a pitch motor, a coaxial cable, and a first support arm arranged opposite a second support arm. The pitch motor is disposed at a front end of the first support arm, a motor shaft of the pitch motor extending in a direction of the second support arm for connecting with one end of an imaging device; a limiting shaft is disposed at a front end of the second support arm, the limiting shaft extending in a direction of the first arm for connecting with another end of the imaging device; a first wiring space is formed in the limiting shaft and a second wiring space is formed in the second support arm, a first end of the coaxial cable sequentially passing through the second wiring space and the first wiring space for electrically connecting with the imaging device.
US11338916B2	Engine and rotatable proprotor configurations for a tiltrotor aircraft A tiltrotor aircraft includes a propulsion system with a fixed engine and a rotatable proprotor. The engine is located below the wing of the tiltrotor aircraft, and the rotatable proprotor assembly is mounted on the top surface of the wing. The engine and proprotor assembly are connected via a series of one or more gearboxes that route the engine output from the engine to the proprotor.
US11338910B2	Integrated landing gear fire detection and fatigue monitoring system A system for an aircraft that includes a plurality of zones including: a first fiber optic cable routed through a zone of the plurality of zones. The first fiber optic cable is attached to a landing gear of the aircraft in the zone of the plurality of zones; and a first controller configured to provide a first optical signal to the first fiber optic cable and obtain a first optical response signal from the first fiber optic cable. The first controller is further configured to determine at least one temperature within the zone of the plurality of zones based on the first optical response signal, the first optical signal, and coherent optical frequency domain reflectometry (COFDR).
US11338909B1	Flow separation control device for an airfoil A combination of an airfoil, turbine blade, or compressor blade with a flow separation control device includes an airfoil, a flow separation control device, and an injection system. The airfoil includes a body with an upper surface and a lower surface that extend from a leading edge to a trailing edge. The flow separation control device includes a plurality of openings on the upper surface of the body. The injection system includes an inlet tube, a pump in gaseous communication with the inlet tube, and a flow regulator in gaseous communication with the pump and the plurality of capillary tube.
US11338907B2	Actuation assemblies for flight control surfaces Actuation assemblies comprise a track comprising a first roller surface, a second roller surface opposite the first roller surface, and a curved section. Actuation assemblies further comprise a carriage operatively coupled to a flight control surface, a first roller rotatably supported by the carriage and comprising a first-roller rolling surface engaged with the first roller surface, a second roller rotatably supported by the carriage and comprising a second-roller rolling surface engaged with the second roller surface, and an actuator, whose distal end is operatively coupled to the carriage to selectively translate the carriage along the track and thus to selectively translate the first roller along the first roller surface and the second roller along the second roller surface.
US11338906B2	Propeller system A propeller system includes a rotatable housing having at least one propeller blade mounted thereon and an electric pitch control motor within the rotatable housing. A pitch control member is coupled to the propeller blade and extends through a wall of the rotatable housing. The pitch control motor is configured to move the pitch control member and to thereby vary the pitch of the propeller blade.
US11338905B2	Offset drive arm actuation of inboard flaps Offset drive arm actuation of inboard flaps is disclosed. A disclosed example apparatus includes an inboard flap support for moving an inboard flap. The inboard flap support includes an offset drive arm extending between a first attachment point of the inboard flap and a first pivot of a support, and a linkage extending between a second attachment point of the inboard flap positioned at a different position from the first attachment point and a second pivot of the support.
US11338901B2	Nacelle for a boundary layer ingestion propulsor An aircraft is disclosed having a boundary layer ingestion propulsor. The aircraft comprises an elongated fuselage extending between a nose section and a tail section. The fuselage has an upswept underside in the tail section. The boundary layer ingestion propulsor is positioned in the tail section. The propulsor comprises a fan radially encased by a nacelle circumscribing the fuselage. The nacelle defines a leading edge line extending from a top dead center to a bottom dead center of the nacelle intersecting an axis of rotation of the fan at an angle no greater than seventy degrees.
US11338898B2	Swing-link trunnion truss mount A truss connected to a structure via a fixed rod end attachment and at least one swing-link attachment. A first beam of the truss is connected to a frame member of the structure via a fixed rod end attachment, which locates the truss relative to the frame of the structure. Remaining beams of the truss to be connected to the frame of the structure are attached via swing-link attachments, which can pivot relative to the beam of the truss and the frame of the structure to allow relative movement between the beam and frame. The relative movement allows the structure to flex without imparting additional loads in the truss or the frame of the structure.
US11338893B2	Multi flange design for marine industry A watercraft with improved safety and stability is provided. The watercraft includes a shell defining a plurality of raceways for receiving water during certain maneuvers of the watercraft, thereby excerpting force upon the watercraft in a first direction. The shell is configured so as to prevent or otherwise inhibit the water from excerpting an opposed second force upon the watercraft. An intermediate panel of the shell provides increased flexibility, thereby serving as a shock absorber for the watercraft.
US11338892B2	Autonomous seabased resupply system An exemplary autonomous seabased resupply system includes an unmanned blob positioned in a water body, the blob containing fuel, a pump on the blob configured to pump the fuel through a conduit to a craft, and a ballast system operable to change a vertical position of the blob in the water body.
US11338887B2	Bicycle rear sprocket A bicycle rear sprocket comprises a sprocket body and a plurality of sprocket teeth including a plurality of driving-noise reduction teeth. Each of the plurality of driving-noise reduction teeth comprises an upstream circumferential surface, a downstream circumferential surface, a first chamfer, and a second chamfer. The first chamfer has a first borderline relative to the bicycle outward surface. The second chamfer has a second borderline relative to the bicycle outward surface. A first opposite end of the first borderline and a second opposite end of the second borderline are disposed radially outwardly from each of a first end of the first borderline and a second end of the second borderline with respect to the rotational center axis. A total number of the plurality of driving-noise reduction teeth is equal to or larger than one-third of a total tooth-space number of the plurality of sprocket teeth.
US11338886B2	Bicycle multiple sprocket and bicycle sprocket A bicycle multiple sprocket comprises a plurality of sprockets. The plurality of sprockets includes a first sprocket and a second sprocket. The second sprocket includes a second sprocket body and a plurality of second sprocket teeth extending radially outwardly from the second sprocket body with respect to the rotational center axis. The plurality of second sprocket teeth includes at least one chain-curvature limiting tooth having a chain-curvature limiting surface configured to support an inner link plate of a bicycle chain in the axial direction in a chain-inclining state where the bicycle chain is inclined from the at least one chain-curvature limiting tooth toward the first sprocket so as to prevent one of a plurality of first sprocket teeth from engaging in an outer link space provided between an opposed pair of outer link plates of the bicycle chain.
US11338885B2	Assistance control system An assistance control system includes a sensor mounted on a cycle body of a cycle, and a controller communicable with the sensor and an assistance module of the cycle. The sensor senses operation of the cycle body so as to output a sense signal indicative of a state of usage of the cycle body. Based on the sense signal, the controller switches between a boost mode and a deboost mode. In the boost mode, the controller outputs a control signal to the assistance module so as to control the assistance module to increase assistive torque for driving movement of the cycle body. In the deboost mode, the controller outputs the control signal to the assistance module so as to control the assistance module to decrease the assistive torque.
US11338878B2	Method for recharging an electrical energy storage device storing electrical energy of a plurality of vehicles A method for recharging an electrical energy storage device of all or some of a plurality connected to the chain. All the vehicles connected to the chain being referred to as the stock. Each vehicle includes an electronic circuit connected to the energy storage device. An electric current flowing between the electronic circuits of at least two consecutive vehicles among the vehicles in the stock recharges the energy storage device or devices.
US11338863B1	Retractable gutter system for a vehicle A vehicle includes a body including an A-pillar, and a windshield having an exterior surface and a lateral edge secured to the A-pillar. The A-pillar has a first part and a second part. The first part is positioned on the second part along the lateral edge of the windshield. The first part is movable relative to the second part from a stowed position wherein an outer surface of the first part is flush with an outer surface of the second part, and a deployed position wherein the outer surface of the first part is positioned entirely outward from the outer surface of the second part. The first part includes a movable member that in the deployed position of the first part is shaped to collect water flowing across the exterior surface of the windshield.
US11338858B2	Vehicle with a front and/or rear steering mechanism, based on application of a lateral, horizontal force on the vehicle's chassis A dynamic joint structure (DJS) for movably connecting a wheel set to a chassis of a vehicle, and a vehicle including a front such DJS and a rear such DJS. The DJS includes an upper suspension plate having at least one upper recess with an upper opening; a middle suspension plate having at least one middle recess with a middle opening; and at least one connector assembly including: (i) an elongated bolt defining an insert axis “Zi” along its longer side; and (ii) a restriction unit configured to restrict the movement of the bolt over an XiYi plane that is perpendicular to Zi, for enhancing translation of tilting movements of the chassis of the vehicle into steering movements of the vehicle's wheels set to which the DJS connects.
US11338857B2	Apparatus and method for estimating a slope angle of a road An apparatus and a method are configured for estimating a slope angle of a road. The slope angle of a road is estimated based on a longitudinal slope angle of the road which is calculated based on a Kinematic model, an effective weight corresponding to a control amount of a driver and a filter constant to estimate the slope angle of the road with higher precision in the case of a U-turn, rapid acceleration, or rapid deceleration in which a longitudinal acceleration of the vehicle is remarkably increased. The apparatus includes a controller to estimate the slope angle of the road, based on a longitudinal slope angle of the road which is calculated based on a Kinematic model, an effective weight corresponding to a control amount of a driver and a filter constant, and an output device to output the estimated slope angle of the road.
US11338856B2	Systems and methods for switching between a driver mode and an autonomous driving mode for a vehicle A vehicle system includes a steering wheel configured to output an output based on an input from a user, and a controller configured to: determine a target orientation of front wheels of a vehicle based on vehicle environment information, determine whether an orientation of the front wheels of the vehicle based on the output from the steering wheel deviates from the target orientation, disengage the steering wheel from the front wheels in response to determination that the orientation of the front wheels deviates from the target orientation, adjust the orientation of the front wheels to the target orientation and provide a feedback in response to adjusting the orientation of the front wheels to the target orientation.
US11338855B2	Optimal planner switch method for three point turn of autonomous driving vehicles A three-point-turn is planned and executed in the operation of an autonomous driving vehicle (ADV). A candidate route from a start point and going through an end point is determined, the start point and the end point being in lanes associated with opposite travel directions. The candidate route is categorized into partially overlapping first, second, and third segments. A total cost associated with the candidate route is determined based at least in part on the first and second segments. Whether the total cost is below a threshold cost is determined. In response to a determination that the total cost is below the threshold cost, the three-point-turn is planned based on the candidate route. Further, driving signals are generated based at least in part on the planned three-point-turn to control operations of the ADV.
US11338851B2	Hitch assist system featuring trailer location identification A hitch assist system is provided herein. The system includes an imager for capturing images of a rear-vehicle scene containing a trailer and a controller for processing the captured images. A device is disposed at a trailer location and has a display configured to flash a shape at a predetermined frequency and alternating in color. The controller identifies the shape in the captured images to determine the trailer location.
US11338843B2	Worm gear for a worm gear mechanism of a vehicle steering system with a carrier ring injected between a hub and a toothed wheel A worm gear for a worm gear system of a motor vehicle steering device may include a hub, a support element, and a gear rim. The gear rim may have a multiplicity of teeth that extend radially outward from a central encircling annular web. The support element may be a support ring that by means of an injection-molding method is injected between the gear rim and the hub. The support element may connect in a form-fitting manner the hub and the gear rim. The gear rim may include reinforcement ribs that, on both end sides, from the teeth extend radially in a direction of a worm gear longitudinal axis.
US11338840B2	Clamping device for a steering column and adjusting device for a steering column A clamping device for a longitudinally adjustable and/or vertically adjustable steering column of a vehicle, has an actuating lever, an actuating component, a tie bolt and a mating component, wherein the actuating component is assigned to the actuating lever, and the mating component is assigned to the tie bolt, and wherein the actuating component is movable relative to the mating component between a release position and a fixing position. A solid damping element is provided for damping a relative movement between the actuating component and the mating component. An adjusting device is furthermore shown.
US11338838B2	Steering wheel cover A steering wheel cover including a stretch fabric ring having a c-shaped cross-section forming a three-hundred-sixty angular degree circle, a first frictitious layer lining at least some of the inside of the stretch fabric ring excepting an angular fabric-only portion of the three-hundred-sixty degree circle, and a second frictitious layer covering some of the outside of the stretch fabric ring, but not covering the angular fabric-only portion.
US11338835B2	High load capacity collapsible carts Compressible carts and methods for using the same are provided. The compressible carts include a rigid frame having a front wall, a rear wall, a right sidewall, a left sidewall, a bottom wall, a rotatable base panel, a rigid cover panel, a handle, and a plurality of wheel assemblies. The compressible carts may also include on each sidewall one or more fastening mechanisms, such as slideable members cooperatively engaging tracks or fastening connectors, and are movable between an open position to allow the sidewall to fold inwardly, to a closed position to selectively lock the panels of the sidewall. The plurality of wheel assemblies may include a plurality of rotatable swivel wheels mounted underneath the bottom wall, or a plurality of wheels rotatably coupled to a plurality of spokes, where each spoke is coupled to a revolving spindle.
US11338829B2	Oil carryover reduction system A system is provided that includes a controller configured to determine one or more propulsion-generating vehicles in a group of propulsion-generating vehicles that have an increased risk for damage to an engine system based on operation at a fueling level that is less than a designated threshold fueling level for at least a designated time period. The controller is further configured to determine respective power outputs for the propulsion-generating vehicles in the group such that the one or more propulsion-generating vehicles having the increased risk for damage to the engine system do not operate below the designated threshold fueling level for longer than the designated time period.
US11338827B2	Autonomous vehicle and system for autonomous vehicle Embodiments of the present disclosure relate to an autonomous vehicle and a system for the autonomous vehicle. The system may include a master computing unit configured to control operations of the autonomous vehicle; a slave computing unit communicatively coupled to the master computing unit and configured to control the operations of the autonomous vehicle in response to detecting a failure of the master computing unit; at least one lidar configured to acquire environmental information around the autonomous vehicle; and a switch communicatively coupled to the at least one lidar, the master computing unit and the slave computing unit, and configured to provide the environmental information to the master computing unit and the slave computing unit for controlling the autonomous vehicle.
US11338823B2	Multiple sensor data storage with compressed video stream in autonomous driving vehicles An ADV includes a method to combine data from multiple sensors. The method compresses video data from a camera to generate compressed video data. The compressed video data are segmented. The method time synchronizes each segment of the compressed video data with data from other sensors. The method then combines each segment of the compressed video data with the corresponding time-synchronized sensor data for the other sensors. In one embodiment, each segment of the compressed video data is independently decodable. In another embodiment, each segment of the compressed video data includes a compressed video unit that is prepended with a buffered portion of the compressed video data that immediately precede the compressed video unit. The length of the compressed video unit is smaller than the length of the independently decodable segment to offer finer granularity in time synchronizing the compressed video data with the other sensor data with a tradeoff.
US11338821B2	Display system, display method, and storage medium A display system includes a display that displays a first image simulating a road on which a host vehicle is traveling, and a display controller that causes the display to display a second image simulating a recommended lane given to a controller that performs driving control of the host vehicle at a position associated with the first image, and to display a third image simulating a target trajectory generated by the controller that performs driving control of the host vehicle at a position associated with the first image, wherein the display controller changes the third image to an image simulating the target trajectory for lane change without changing a display position of the second image when the controller executes driving control for causing the host vehicle to return to an original lane after causing the host vehicle to perform lane change.
US11338820B2	Vehicle automated driving system A vehicle automated driving system 100 comprises a surrounding environment information acquiring device 10, a vehicle information acquiring device 20, a driver information acquiring device 30, a package selecting part 90, a package proposing part 91, an automated driving executing part 92, and a rejection count detecting part 93. The package selecting part determines the driving assistance package based on at least one of the surrounding environment information, the vehicle information, and the driver information, selects the determined driving assistance package if the rejection count of the determined driving assistance package is less than a predetermined threshold value, and selects a driving assistance package different from the determined driving assistance package if the rejection count of the determined driving assistance package is the threshold value or more.
US11338818B2	Autonomous driving assistance method and device An autonomous driving assistance device includes a manual driving control section, an autonomous driving control section, and a travelling condition determining section. If it is detected that there is a malfunction in a first sensor during control of the autonomous driving of the vehicle, the autonomous driving control section executes emergency autonomous driving until a predetermined condition is satisfied while changing, based on the determined travelling condition, a driving manner of an emergency autonomous driving as compared with a driving manner of the autonomous driving executed before no malfunctions are detected in the first sensor; and after the emergency autonomous driving is terminated, the autonomous driving assistance device being configured to selectively execute one of: causing the autonomous driving control section to stop the vehicle; and causing the manual driving control section to control the manual driving.
US11338816B2	Over-the-air flashing and reproduction of calibration data using data regression techniques A data map is modeled to generate a modeled data map, the data map including a calibration to control vehicle operation over various weather conditions encountered by a vehicle, the modeled data map characterizing data elements of the data map according to a mathematical model. The modeled data map is sent to the vehicle to expand into at least a portion of the data map to control the vehicle operation.
US11338814B2	Road surface condition assessing device A road surface condition assessing device includes: a tire-mounted device; and a vehicle body system. The tire-mounted device includes: a vibration detector that outputs a detection signal of a vibration on a tire; a waveform processor that generates the road surface data; and a first data communication unit. The vehicle body system includes: a second data communication unit; and a road surface evaluation unit that evaluates the road surface condition. The tire-mounted device transmits an advertise signal including the road surface data indicative of a result of a waveform process on the detection signal and a waveform processing value corresponding to the road surface condition. The vehicle body system evaluates the road surface condition based on the waveform processing value.
US11338813B2	System and method for merge assist using vehicular communication A computer-implemented method for controlling a vehicle system of a host vehicle merging into a lane. The method includes determining an actual distance between the host vehicle and the one or more remote vehicles. The actual distance is a longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes determining a safe distance for merging into the lane based on a relative position of the host vehicle to the one or more remote vehicles, a speed of the host vehicle, and a speed of the one or more remote vehicles. The safe distance is a second longitudinal distance between the host vehicle and the one or more remote vehicles. The method includes controlling the vehicle system of the host vehicle to assist a merge maneuver by the host vehicle according to the actual distance and the safe distance.
US11338811B2	Mode selector module for a vehicle component Techniques are provided for operating a vehicle in a first vehicle mode; operating at least one component of the vehicle in a first component mode; detecting a first change in operation of the vehicle from the first vehicle mode to a second vehicle mode different from the first vehicle mode; based on the detected the first change in the operation of the vehicle, predicting a second change in operation of the vehicle; in response to predicting the second change in operation of the vehicle, operating the at least one component in a second component mode different from the first component mode prior to the predicted second change in operation of the vehicle.
US11338808B2	Autonomous driving method and apparatus The present disclosure provides an autonomous driving method and an apparatus. The method includes: receiving a currently collected image transmitted by a unmanned vehicle, where the currently collected image is an image collected in a target scenario; acquiring current driving data according to the currently collected image and a pre-trained autonomous driving model, where the autonomous driving model is used to indicate a relationship between an image and driving data in at least two scenarios, and the at least two scenarios include the target scenario; and sending the current driving data to the unmanned vehicle. Robustness of the unmanned driving method is improved.
US11338807B2	Dynamic distance estimation output generation based on monocular video Aspects of the disclosure relate to a dynamic distance estimation output platform that utilizes improved computer vision and perspective transformation techniques to determine vehicle proximities from video footage. A computing platform may receive, from a visible light camera located in a first vehicle, a video output showing a second vehicle that is in front of the first vehicle. The computing platform may determine a longitudinal distance between the first vehicle and the second vehicle by determining an orthogonal distance between a center-of-projection corresponding to the visible light camera, and an intersection of a backside plane of the second vehicle and ground below the second vehicle. The computing platform may send, to an autonomous vehicle control system, a distance estimation output corresponding to the longitudinal distance, which may cause the autonomous vehicle control system to perform vehicle control actions.
US11338805B2	Method and apparatus for controlling mild hybrid electric vehicle A method of controlling a mild hybrid electric vehicle may include determining whether a Smart Cruise Control (SCC) mode is set according to a signal input through a driver interface; determining whether an Start Stop Control (SSC) entrance condition is satisfied when the SCC mode is set; when the SSC entrance condition is determined by the control unit, to be satisfied to enter an SSC mode, interrupting a supply of fuel to an engine and turning off the engine; monitoring a distance in which the control unit determines whether a distance to a front vehicle is increased or decreased based on a front distance signal transmitted from a detecting unit electrically-connected to the control unit; and increasing or decreasing a vehicle speed by controlling the engine, a Mild Hybrid Starter Generator (MHSG), or an Electronic Stability Control (ESC) based on the monitoring of the distance.
US11338804B2	Vehicle control device A vehicle control device comprises an operation amount sensor for measuring an operation amount of an accelerator element, an object sensor for detecting an object ahead of a vehicle, and a controller for applying a normal operation drive force which is determined depending on the operation amount to the vehicle. The controller executes an adaptive cruise control for applying a drive force required for an acceleration of the vehicle to become equal to an adaptive cruise control acceleration to the vehicle. The adaptive cruise control acceleration is an acceleration which increases as a difference between an inter-vehicle distance from the vehicle to an objective-forward-vehicle and a target inter-vehicle distance increases. When an erroneous operation start condition becomes satisfied, the controller ends the adaptive cruise control, and executes an erroneous operation related control for applying a drive force which is smaller than the normal operation drive force to the vehicle.
US11338802B2	Control system and control method for controlling behavior of motorcycle The present invention provides a control system and a control method capable of appropriately supporting driving of a motorcycle by a rider.The control system includes an execution unit that causes the motorcycle to execute an automatic decelerating operation in a case where an obstacle is located in a predetermined range where a collision avoiding operation of the motorcycle is required, a lane position information acquiring unit that acquires relative position information of a lane boundary with respect to the motorcycle during traveling, and a detection angle range setting unit that set a detection angle range of a forward environment detecting device to be wide in a case where a determination reference is satisfied, in which the determination reference includes a condition that the lane position information acquired by the lane position information acquiring unit satisfies a prescribed condition.
US11338800B2	Vehicle control device A vehicle control apparatus includes a time-to-collision acquisition unit that acquires time to collision that is a time period until a time of collision of an own vehicle with a front obstacle, an overlap rate acquisition unit that acquires an overlap rate indicating a relative positional relationship between the own vehicle and the front obstacle in a lateral direction perpendicular to a traveling direction of the own vehicle, a determination unit that performs execution determination of automatic braking control of the own vehicle, on the basis of the time to collision and the overlap rate, and that, when the overlap rate is increasing by the front obstacle approaching the own vehicle in the lateral direction, determines start timing of the automatic braking control as earlier timing than when the overlap rate is not increasing, and an automatic controller that executes the automatic braking control at the start timing.
US11338799B2	Driving support apparatus A driving support apparatus (10) executes collision prevention control for avoiding collision with the object when a possibility of a vehicle (VA) colliding with an object based on object information (e.g., distance, direction, and relative speed) acquired by a millimeter wave radar device (21) and a camera device (22) is high. Further, the driving support apparatus does not execute the collision prevention control when an accelerator pedal operation amount is equal to or larger than a stop threshold value. However, the driving support apparatus executes the collision prevention control even when the accelerator pedal operation amount is equal to or larger than the stop threshold value within a specific period of from a start point at which a predetermined erroneous operation condition is satisfied, to an end point, which is a time point after a predetermined consideration period has elapsed since the erroneous operation condition has no longer been satisfied.
US11338793B2	Vehicle control apparatus A vehicle control apparatus for a vehicle includes a catalyst deterioration diagnosing unit, an engine controlling unit, and a diagnosis start determining unit. The catalyst deterioration diagnosing unit executes a deterioration diagnosis of a catalyst included in an exhaust system of an engine provided in the vehicle. The engine controlling unit controls an air-fuel ratio of the engine to a lean side and thereafter to a rich side during the deterioration diagnosis of the catalyst. The diagnosis start determining unit prohibits the deterioration diagnosis of the catalyst from being executed when a deceleration rate upon deceleration of the vehicle is high, and permits the deterioration diagnosis of the catalyst to be executed when the deceleration rate upon deceleration of the vehicle is low.
US11338791B2	Electric device and method for controlling electric device A method for controlling an electric device including: a step of comparing the rotation speed of an internal combustion engine at the time when it has been determined that the internal combustion engine is to transition to a rotation stop state with a specified threshold; and a step of performing rotation-speed increasing control, in a case where the rotation speed of the internal combustion engine at the time of the determination is higher than the threshold, in which in a case where the rotation speed of the internal combustion engine at the time of the determination is not higher than the threshold, the rotation speed of the internal combustion engine is not made higher than the rotation speed at the time of the determination but is let to decrease to stop the internal combustion engine.
US11338789B2	Method for controlling a drive system, and drive system The invention relates to a method for controlling a drive system with at least two drive units (20), each of which is paired with at least one control unit (22), wherein —a total target torque (30) is calculated by means of a master control unit (22a), —the total target torque (30) is divided into respective individual target torques (32) for each of the drive units (20) by the master control unit (22a), and —the drive units (20) are actuated by the paired control units (22) on the basis of the corresponding individual target torques (32). The invention is characterized in that the threshold torques (34) corresponding to the drive units (20) are ascertained and taken into consideration by the master control unit (22a) when dividing the total target torque (30).
US11338783B2	Electropneumatic trailer control-valve unit for North America An electropneumatic trailer control-valve unit for a vehicle includes a storage port for coupling a store of compressed air for a trailer, a brake-pressure port, and a brake-pressure pilot-control unit configured to output at least one first control pressure. The electropneumatic trailer control-valve unit further includes a brake-pressure main-valve unit configured to receive the first control pressure and to output a brake pressure at a brake-pressure port, a trailer operating-pressure port configured to receive a trailer operating pressure; and a pneumatically switched trailer protection valve with a protection-valve control port which is connected to the trailer operating-pressure port for receiving the trailer operating pressure. The trailer protection valve switches from a first switching position into a second switching position if the trailer operating pressure exceeds a predetermined first threshold value.
US11338777B2	Two speed trailer jack A linear jack includes a first outer sleeve, an inner sleeve disposed at least partially within the first outer sleeve, a second outer sleeve disposed at least partially within the inner sleeve, a translating screw disposed at least partially within the second outer sleeve, and a cover sleeve coupled to the translating screw. The first outer sleeve is threadedly coupled to the inner sleeve. The second outer sleeve is threadedly coupled to the translating screw. The translating screw is disposed at least partially within the cover sleeve. The cover sleeve is configured to translate with the translating screw.
US11338775B2	Apparatus and method for controlling wiper of vehicle A vehicle wiper control apparatus monitors whether warpage occurs in a wiper strip made of a rubber-elastic material that is provided in a wiper blade. When a wiper of a vehicle is turned off and the warpage occurs in the wiper strip, the control apparatus controls the wiper mechanism to move the wiper blade to a parking position thereby preventing deformation of the wiper strip and maintaining the performance thereof.
US11338774B2	Heating plate, conductive pattern sheet, vehicle, and method of manufacturing heating plate A heating plate includes: a pair of glass plates; a conductive pattern disposed between the pair of glass plates and defining a plurality of opening areas; and a joint layer disposed between the conductive pattern and at least one of the pair of glass plates; wherein the conductive pattern includes a plurality of connection elements that extend between two branch points to define the opening areas; and a rate of the connection elements, which are straight line segments connecting the two branch points, relative to the plurality of connection elements, is less than 20%.
US11338773B2	Transmission control device, portable device, vehicle system, transmission control method, control method, and control program product A transmission control device that drives multiple antennas having different transmission ranges controls a genuine transmission antenna among the multiple antennas to transmit, with use of a carrier wave, a genuine code for activating a portable device and a noise determination purpose burst signal for determining a noise in the portable device after the transmission of the genuine code, and controls each antenna of a remaining antenna group, which includes remaining antennas except the genuine transmission antenna, to transmit the noise determination purpose burst signal at a transmission time point, which is set different from one another and shifted from a transmission time point of the noise determination purpose burst signal from the genuine transmission antenna. The transmission ranges of the multiple antennas including the genuine transmission antenna are set to not have a common area.
US11338769B2	Systems and methods for immobilizing a vehicle A device may receive an arming signal associated with immobilizing a vehicle. The device may monitor, based on receiving the arming signal, a current associated with an electrical power output from a battery of the vehicle. The device may detect that a measurement of the current satisfies a threshold associated with an ignition component starting an engine of the vehicle. The device may control, based on detecting that the current satisfies the threshold, a bypass circuit to reduce the electrical power output to prevent the ignition component from starting the engine.
US11338766B2	Webbing length adjustment device A webbing length adjustment device has an outer shell, an adjustment assembly, and an elastic member. The adjustment assembly is disposed in and is moveable relative to the outer shell, and has an operating member having a lateral pressing plate portion and a sliding member moving relative to the operating member. The lateral pressing plate portion is formed on the operating member, is located above the outer shell, and is located beside the second through hole for giving more areas to exert force easily and operate conveniently. The lateral pressing plate portion is located at an outer side of a first webbing. There is no interference between the first webbing and user's hand. The elastic member is disposed in the outer shell, and is connected to the outer shell and the operating member for giving a restoring force to the operating member. The outer shell is hard to damage.
US11338765B2	Lateral shock absorber and child car safety seat therewith A lateral shock absorber includes a protective fender and a locking mechanism. The protective fender is pivoted to a base of a child car safety seat and pivotally switchable between a folded state or an unfolded state relative to the child car safety seat. The locking mechanism is for selectively engaging with the protective fender to restrain the protective fender from switching to the unfolded state or disengaging from the protective fender to allow the protective fender to switch to the unfolded state when the protective fender is located in the folded state. The protective fender includes a driving block, a supporting block and a combining assembly. The driving block is pivoted to the base, and the supporting block is pivoted to the driving block and engages with the driving block by the combining assembly.
US11338763B2	Pedestrian protection device for vehicle A plurality of airbags 14 are arranged, in a deflated state, at mutually different heights behind respective panels of a front face part of a vehicle, and are capable of being deployed frontward from the front face part of the vehicle. A head position deduction unit 19 of an ECU 15 deduces the height position of the head of a pedestrian from information provided by a vehicle forward camera 12 and a millimeter-wave radar 13. A collision detection unit 18 of the ECU 15 computes, from information provided by the millimeter-wave radar 13 and a vehicle speed sensor 11, a time-to-collision TTC with respect to the pedestrian, and, after elapse of the time-to-collision TTC, detects a collision between the vehicle and the pedestrian. When a collision between the vehicle and the pedestrian is detected by the collision detection unit 18, an airbag control unit 20 of the ECU 15 deploys, from among the plurality of airbags 14, an airbag 14 that can be deployed at the pedestrian's head height position deduced by the head position deduction unit 19.
US11338760B2	Cushion of airbag apparatus A cushion of an airbag apparatus may include: a rear panel having a gas inlet formed at the rear thereof, and a first connecting end formed along the edge thereof and deployed forward when gas is introduced into a primary filling room open to the front; and a front panel having a second connecting end formed along the edge thereof at the front of the rear panel and coupled to the first connecting end, and a passenger support region which is formed at the front surface thereof and deployed forward when gas is introduced into a secondary filling room open to the rear.
US11338757B2	Airbag unit for a vehicle seat There is proposed a vehicle seat configured to support an occupant (401) in a sitting position, the seat comprising: a squab (27), a backrest (28), and an airbag unit. The airbag unit comprises an inflatable bag (1) and an inflator (34). The airbag comprises an inflatable chamber (8, 9; 208). The airbag further comprises an inflatable guide (2), connected to the inflator and the inflatable chamber. Upon actuation of said inflator, said inflatable guide is at least partially inflated before the inflatable chamber, thereby initially urging the inflatable chamber away from the backrest of the seat. The airbag is configured such that after the inflatable guide is at least partially inflated, the inflatable chamber inflates into a deployed position in which it defines an inflated shroud which extends over said sitting position and provides lateral protection to said occupant of the seat in said sitting position.
US11338756B2	Airbag device with horn switch body An airbag device with a horn switch body, configured so as to be installed in an upper surface side in a boss portion near a center of a steering wheel, includes: an airbag which inflates by receiving inflation gas; an inflator for supplying inflation gas to the airbag; a pad covering the folded airbag; a mounting base made of sheet metal which holds the airbag, the inflator, and the pad; a horn switch body having an assembling pin to be assembled to a main body side of the steering wheel; and a support plate made of a sheet metal which supports the horn switch body as a configuration attached to a lower surface side of the mounting base. A case around the assembling pin, the mounting base, or the support plate is provided with a spacer capable of preventing rattling of the switch disposition portion in the case.
US11338755B2	Energy absorbing feature for seatback A seat includes a seat bottom having an occupant support surface, a seatback connected to the seat bottom, the seatback having an occupant support side cooperating with the occupant support surface, and a rear side, and an energy absorbing feature including a rigid member connected to the rear side of the seatback. The rigid member is movable between a storage position adjacent the seatback, and a deployed position extending into a cargo space of a vehicle upon detection or occurrence of an impact event. In the deployed position, the rigid member is capable of interfacing with cargo, a cargo floor, or both, to reduce force imparted on and deflection of the seatback and deflect cargo from impacting the seatback.
US11338753B2	Information processing apparatus, information processing method, and program An information processing apparatus (10) includes a computation unit (110), a selection unit (120), and a processing unit (130). The computation unit (110) analyzes a sensing result acquired by sensing a vehicle running on a road, and thereby computes the number of occupants in the vehicle and a certainty factor of the number of the occupants. As one example, the computation unit (110) computes reliability in the case of determining that a person exists related to each seat of the vehicle, and uses the reliability for each seat to compute a certainty factor related to each possible number as the number of the occupants in the vehicle. The selection unit (120) selects a sensing result with the computed certainty factor of the number of occupants which does not satisfy a predetermined criterion as an analysis result. The processing unit (130) allows the sensing result selected by the selection unit (120) to be in the state of being distinguishable from the other sensing results.
US11338750B2	Method and system for reporting diagnostic trouble code set in vehicle is collision-related A method and computing system for determining whether a DTC set in a vehicle involved in a collision is collision-related or non-collision-related. The method can include determining a vehicle model associated with the vehicle, determining a DTC set within an ECU in the vehicle, determining a damaged portion in the vehicle, determining the DTC is collision-related, and outputting a collision report that indicates the DTC is collision-related. The determined damaged portion indicates where the vehicle was damaged by the collision. Determining the DTC is collision-related can include determining the damaged portion in the vehicle matches a reference vehicle portion associated with both a component attributable to setting the DTC and the vehicle model associated with the damaged vehicle. The collision report can indicate that a different DTC set by the same or a different ECU in the vehicle is non-collision-related.
US11338748B2	In-vehicle power source control device and in-vehicle power source system Provided is a vehicle power source control device and system that supplies power from an auxiliary power source to an in-vehicle load while suppressing the consumption of power when a failure occurs in the main power source when a vehicle has not been started. When a drive signal generation unit generates an off-signal and a main power source has failed, a power source drive circuit in an in-vehicle power source control device controls a power source circuit such that power is supplied from an auxiliary power source to a control unit. If the drive signal generation unit is generating an off-signal and the main power source is in a failed state, the control unit uses power supplied from the auxiliary power source to control the relay to switch to the first stopped state, and controls the converter to switch to the second permissive state.
US11338745B2	Holder and wire harness with pair of hinged split bodies A holder including a tubular main body that includes a pair of split bodies, and a hinge that couples the pair of split bodies so that the pair of split bodies can be opened and closed, the tubular main body being configured to be inserted into the tube; and a pair of projections that each have a press surface to be pressed against by an ejector pin, and are respectively formed protruding radially outward from outer circumferential surfaces of the pair of split bodies, wherein the pair of projections are formed so that when the pair of split bodies are opened with the hinge used as a pivot point, the pair of projections come into contact with each other before the outer circumferential surfaces of the pair of split bodies come into contact with each other.
US11338744B2	Enclosed toilet system for a truck One or more systems for an enclosed toilet may be mounted to an exterior of a big vehicle such as a truck. One or more systems for an enclosed toilet may be manufactured onto or mounted onto a trailer that may be hitched to a vehicle and towed. The embodiments for the toilet system comprise of a fully functional toilet which is operatively connected to a clean water tank and a waste tank. The clean water tanks and the waste tanks are also each provided with a temperature sensor, a heating element, a cooling element, and a level sensor. The various functions and systems of the toilet function may be electronically monitored and controlled. The one or more systems for a toilet system that may be used on a trailer also comprises of a shower area which has a gravity fed water tank that feeds into a shower head. The one or more systems herein is a fully independent system that provides easy access to a fully and independently functional toilet system.
US11338743B2	Vehicle wheel A vehicle wheel includes: a pair of vertical walls that are provided upright on an outer circumferential surface of a well portion and extend in a circumferential direction; and a sub air chamber member that is provided between the pair of vertical walls to be held by frictional force generated between the sub air chamber member and the pair of vertical walls and includes an extending wall portion.
US11338741B2	Camera mirror vehicle mounting system A vehicle camera mounting system includes, among other things, a first bracket portion that has a first attachment feature that is configured to be secured to an exterior of a vehicle. The first bracket portion extends laterally from the first attachment feature to a second attachment feature. The first attachment feature is provided by a plate that has apertures that are configured to receive fasteners that secure the first bracket portion to the vehicle. The second attachment feature is configured to mount to the vehicle at a location remote from the plate. The system further includes a camera assembly that is secured to the second attachment feature.
US11338739B1	Fishing rod truck rack The fishing rod rack gives the user a place to secure several fishing rods in a truck bed. The fishing rods are held by clips positioned on two posts, which are inserted into openings in the truck bed. The secure clips prevent the fishing rods from falling out of the rack, but the clips can also be adjusted and opened so the fishing rods may quickly be removed once needed. Furthermore, there is a rubber string on each post that runs from the top of the post to an eye hook towards the base of said post.
US11338735B2	Rotatable outside mirror with imager assembly An exterior mirror assembly for a vehicle includes an arm having a proximal end coupled with a vehicle door and a distal end. A mirror assembly is coupled to the arm. The mirror assembly includes an electro-optic element. The mirror assembly is rotatable about the distal end between first and second positions. An imager is disposed proximate to the distal end and configured to capture image data within a blind spot zone of said vehicle
US11338733B2	Device-based systems and methods for detecting screen state and device movement A method for determining usage of a mobile device in a vehicle by a user includes receiving a first value indicating an “off” state of a screen at a first time, operating at least one sensor of the mobile device to obtain first movement measurements, and classifying the first movements as usage movements. The method also includes generating an indication of mobile device usage, receiving a second value indicating an “on” state of the screen at a second time, operating the at least one sensor to obtain second movement measurements, and classifying the second movements as usage movements or non-usage movements. The method further includes maintaining the indication of mobile device usage in response to the second movements being classified as usage movements or changing the indication of mobile device usage to an indication of mobile device non-usage in response to the second movements being classified as non-usage movements.
US11338732B1	Hitch cross path alert systems A hitch cross path alert system for a vehicle is presented. A first sensor may detect whether a hitch is connected to a hitch receiver connected to the vehicle. A second sensor may identify a pedestrian in proximity to the vehicle. A processor may be configured to predict a path of the pedestrian based on data captured by the second sensor and to cause the vehicle to output an audio or visual warning to the pedestrian.
US11338731B2	Color selection for ambient lighting of a vehicle A device for controlling ambient lighting of a vehicle includes a light element in a vehicle interior, a touch-sensitive display unit, and a control unit. The light element emits light in one of a plurality of colors that can be generated by the light element. The display unit displays a plurality of colors of a predefined color spectrum simultaneously in a color scale, and detects a location of a user input made by touching the display unit. Via the detected location, the user input is assigned to an associated color displayed in the color scale and information about the color assigned to the user input is transmitted to the control unit, which controls the light element for emitting light in the color assigned to the user input. The light element and display unit have the same color space, such that the color associated with the user input, displayed on the display unit are the same.
US11338729B2	Communication of autonomous vehicle actions Techniques for communication of autonomous vehicle actions include receiving an intended driving action associated with an autonomous vehicle, determining an intent communication scenario associated with the autonomous vehicle, and based on the intent communication scenario, causing a visualization indicating the intended driving action to be projected onto a roadway.
US11338725B2	Vehicular tailgate illumination system with adjustably positioned illumination device A tailgate illumination system includes an illumination device having (i) a tailgate bracket configured for mounting at a tailgate of a vehicle and (ii) a pivot bracket pivotally mounted at the tailgate bracket. The pivot bracket supports a light source that, when powered, emits light. With the tailgate bracket mounted at the vehicle tailgate, the pivot bracket pivots relative to the tailgate bracket responsive to gravitational force acting on the pivot bracket as the tailgate moves from a closed position to an opened position. With the tailgate bracket mounted at the vehicle tailgate, and with the tailgate in the closed position, light emitted by the light source, when powered, illuminates a ground region rearward of the vehicle. With the tailgate bracket mounted at the vehicle tailgate, and when the tailgate is in the opened position, light emitted by the light source, when powered, illuminates the ground region rearward of the vehicle.
US11338721B2	Vehicle light fixture A vehicle lamp is provided on a vehicle capable of traveling around a corner by inclining a vehicle body in a turning direction. The vehicle lamp includes a headlamp mounted on a front portion of the vehicle, and a combination lamp disposed on a vehicle body cover in a region adjacent to the headlamp so as to be visible from the front of the vehicle. The combination lamp includes a plurality of light emitting segments. Depending on arrangement locations, the light emitting segments differ in at least one of the shape of, the size of, the color of, and a distance between the light emitting segments.
US11338719B2	Slide-out room mechanism with cable drive A slide-out room system includes a motor-driven sheath with wound cables for extending and retracting the slide-out room. The cables and the sheath are configured such that rotation of the sheath in one direction displaces the cables to extend the room and such that rotation of the sheath in an opposite direction displaces the cables to retract the room.
US11338717B2	Integrated vehicle vending machine A device that includes a housing configured to couple to a vehicle console. The device further includes a lid that is configurable between a closed position and an open position. The device further includes a lock is configured to transition from a locked configuration to an unlocked configuration. In the locked configuration, the lock is configured to maintain the lid in the closed position. In the unlocked configuration, the lock is configured to release the lid from the closed position. The device further includes a user interface configured to display products, receive a user input identifying a product, receive card information, send an authorization request that requests a purchase of the product, and send an authorization signal to a controller in response to receiving an approval message. The device further includes the controller configured to send an actuation signal to unlock the lock in response to receiving the authorization signal.
US11338713B2	Vehicle seat cover and vehicle seat The present disclosure relates to a vehicle seat cover designated for a detachable attachment to a headrest of a vehicle seat. The vehicle seat cover comprises a pliable first layer with a first recess and a pliable second layer with a first recess, the recesses being configured for accommodating the headrest rod. The recesses each have an edge opening. In the state of the vehicle seat cover attached to the headrest rod one edge opening is partially or completely covered by an edge which limits the other recess.
US11338705B2	Seat assembly of vehicle A seat assembly of a vehicle may include a support having a lower end portion connected to a floor of the vehicle; a seat frame having a connection portion provided above the support and having an entire slope which is changed by a curvature of the connection portion when the connection portion is slid, the connection portion being formed in a curved line or a curved surface; and a seat mounted on the seat frame and configured for implementing reclining by having a slope which is changed together with the seat frame when the seat frame is slid on the support.
US11338704B2	Easy entry latch for vehicle seat An occupant support includes a vehicle seat mounted to a foundation frame for sliding the vehicle seat longitudinally in a vehicle. The vehicle seat is movable from a slid-back configuration to a forward-seating configuration and may be changed from a horizontal-use configuration to a tilted configuration for easy entry into or exit from a rear row of the vehicle. The vehicle seat may be locked in the tilted configuration.
US11338699B2	Apparatus, method, battery pack and electrical system for determining electrode information of battery An apparatus and method for determining electrode information of a battery including a positive electrode and a negative electrode, and a battery pack including the apparatus. The apparatus includes a sensing unit configured to measure a voltage and a current of the battery, and a processor. The processor generates a V-dQ/dV curve based on the voltage and the current of the battery. The V-dQ/dV curve indicates a relationship between V (the voltage of the battery) and dQ/dV (a ratio of an amount of change dQ of the remaining capacity to an amount of change dV of the voltage of the battery). The processor detects a plurality of feature points from the V-dQ/dV curve. The processor determines information associated with each of the first electrode and the second electrode as the electrode information based on the plurality of feature points.
US11338697B2	Vehicle-mountable control device and charging system A vehicle-mountable control device configured to control a vehicle including a charging port for DC power and an auxiliary device includes a determination unit and an information obtainment unit. The information obtainment unit is configured to obtain prescribed facility information about a power feeding facility. The determination unit is configured to permit an auxiliary device driving mode when it is determined that the power feeding facility corresponds to the auxiliary device driving mode based on the facility information, and not permit the auxiliary device driving mode when it is determined that the power feeding facility does not correspond to the auxiliary device driving mode based on the facility information.
US11338687B2	Charging station for a container transport vehicle, container transport vehicle, and system comprising same A charging station for a container transport vehicle includes a charging device and a contacting unit connected thereto, to establish a connection between the charging station and contacts of a rechargeable battery of a container transport vehicle for battery charging process. The charging station, including the contacting unit and the charging device, is designed as a mobile unit. The contacting unit and the charging device are arranged in a housing, and the housing has an opening through which the contacting unit can be moved for a charging process. Optionally, battery contacts and a funnel-shaped guide are provided, and the contacts are arranged near the guide such that a contacting unit of the charging station can be guided to the battery contacts, by the guide, for a battery charging process. The disclosure also relates to a system including a charging station and a container transport vehicle.
US11338681B2	Vehicle and information output method therefor An information output method includes determining, when a first condition is satisfied, whether a second or a third condition related to a pop-up in a first form from a time point of ignition off is satisfied, and setting at least one first pop-up request corresponding to the pop-up in the first form to a second pop-up request corresponding to a pop-up in a second form output during ignition on when the second condition or the third condition is satisfied, wherein whether the second condition is satisfied is determined in consideration of a number of first pop-up requests expected at the time point of ignition off, and whether the third condition is satisfied is determined in consideration of the number of first pop-up requests which are not displayed as pop-ups in the first form after ignition off from previously generated first pop-up requests.
US11338680B2	Air imaging apparatus for vehicle and human-machine interactive in-vehicle assistance system Disclosed is an air imaging apparatus for a vehicle. The air imaging apparatus for vehicle being mounted in a vehicle, comprises: an image source configured for generating a graphic for display; and an imaging magnifier configured for magnifying the graphic generated by the image source and forming a real image in the air inside a vehicle. Further disclosed is a human-machine interactive in-vehicle assistance system, comprising the air imaging apparatus for vehicle as described above and a gesture recognition apparatus nearby the real image. With the enlarged image, the icons for displaying contents are also enlarged; as such, the gesture recognition apparatus can easily recognize which command icon is to be touched by the user's gesture. The gesture sliding distance is also correspondingly enlarged for the user's sliding gesture operation, which significantly lowers the requirement on the precision of the gesture recognition apparatus.
US11338674B2	Ergonomic control mechanism for self-propelled flooring equipment Control of a self-powered floor preparation machine is provided by an ergonomic controller having a guarded control stick which has various characteristics, including its pitch, roll, yaw and height, that may all be adjusted.
US11338673B1	Selectable four-wheel drive system A drive system for a vehicle having a rear drive assembly powered by a first power source, a front drive assembly in selective electrical communication with a second power source, a selector switch to selectively permit or prevent electrical communication between the front drive assembly and the second power source, and an output capacity sensor to detect an output of the first power source, where the rear drive assembly drives the vehicle when the selector switch is in a first position and both the rear and front drive assemblies drive the vehicle when the selector switch is in a second position and the output capacity sensor detects that the output of the first power source meets a threshold output.
US11338670B2	Transmission with power electronics module A transmission may include a housing and also a power electronics module, the power electronics module including a carrier element with at least one power switching element with a cooling surface and also a cooling body, which may be connected in a thermally conductive manner to the cooling surface of the at least one power switching element. The housing may have an oil space for at least partially accommodating transmission components. The power electronics module may be at least partially arranged inside the oil space of the transmission.
US11338669B1	Electric motor and gear assembly A reduction drive assembly includes a spindle that defines an aperture and a motor output shaft extending through the aperture. The reduction drive assembly includes an output hub and a planetary gear assembly. The planetary gear assembly includes a ring gear fixed to the output hub, a first stage sun gear coupled to and driven by the motor output shaft, a second stage sun gear, a planetary gear carrier engaged to the second stage sun gear, first stage planetary gears each of which is supported by a respective support pin of the planetary gear carrier and meshed with the first stage sun gear and the ring gear, carrier pins extending from a first end of the spindle, and second stage reduction gears each of which is rotationally mounted on a respective one of the carrier pins and is meshed with the second stage sun gear and the ring gear.
US11338668B2	Fuel filler pipe A tubular fuel filler pipe body is a blow molded body and is adapted to connect to a fuel tank at one end thereof. The fuel filler pipe body includes in an outer circumferential surface of another end side thereof an annular recessed groove. The fuel filler pipe body includes an opening of the other end thereof to which a nozzle guide is mounted. The nozzle guide includes on an one end side thereof an annular covering portion configured to cover annularly the outer circumferential surface of the other end side of the fuel filler pipe body. An annular rubber sealing member configured to seal between an inner circumferential surface of the annular recessed groove and an inner circumferential surface of the annular covering portion fits with the annular recessed groove.
US11338666B2	Heat exchanging system A system for attaching a heat exchanger to a vehicle includes a first bracket and a second bracket. The first bracket is secured to the heat exchanger and has a first plate. The first plate includes front and back surfaces. The first plate defines first and second notches on opposing peripheral edges of the first plate. The second bracket is secured to the vehicle. The second bracket has a second plate, a hook, and a clip. The second plate has an outer surface. The hook and the clip extend from opposing edges of the outer surface. The outer surface is configured to engage the front surface of the first plate. The hook and the clip are configured to extend through the first and second notches, respectively, and to engage the back surface of the first plate to secure the second bracket to the first bracket.
US11338665B1	Electrified vehicle thermal management system and thermal management method An electrified vehicle thermal management system includes, among other things, a transmission, an inverter, and a terminal block disposed between the transmission and the inverter. The terminal block includes a conduit configured to deliver transmission fluid from the transmission to the inverter. An electrified vehicle thermal management method includes circulating a transmission fluid between a transmission, a terminal block, and an inverter, and using the transmission fluid to manage thermal energy within the inverter.
US11338664B2	Vehicle wheel having a suspension and a steering device A vehicle wheel having a suspension and a steering device is capable of not only simplifying a driving system but also reducing the number of parts and reducing weight. The vehicle wheel includes a suspension combined with a damper and a spring in a housing of a stator of an in-wheel motor embedded in each wheel of a vehicle and a steering device directly connected to the suspension.
US11338659B2	Method of making a weather strip and bright strip assembly for a vehicle door Methods of making a weather strip and bright strip assembly for a vehicle door include extruding a weather strip that has a longitudinal shape along an X axis, a sealing body made of at least a first material, and a carrier body made of at least a second material that is harder than the first material. The methods further include cutting at least in part a longitudinal end of the carrier body along the X axis, and removing the longitudinal end; molding a curved or angled end onto the weather strip, in replacement of the longitudinal end, wherein the curved or angled end extends between the X axis and a Y axis; and mounting a bright strip onto the carrier body, the bright strip including a first curved or angled portion covering at least in part the curved or angled end and a second longitudinal portion covering at least in part the carrier body.
US11338653B1	Protective windshield system A system that includes a protective windshield system that deflects particulate away from a vehicle. The protective windshield system includes a sensor that senses the particulate and emits a signal indicative of the particulate. A deflection system deflects the particulate away from the vehicle. A controller couples to the sensor and to the deflection system. The controller detects the particulate and activates the deflection system to deflect the particulate away from the vehicle.
US11338648B2	Engine for a transport refrigeration unit with air management valve Disclosed is a transport refrigeration unit (TRU) having: an engine configured to power a refrigeration system of the TRU, the engine including an air intake, the engine within an engine compartment of the TRU; an air management valve (AMV) fluidly coupled to the air intake; a first duct fluidly coupled to the AMV and including a first inlet within the engine compartment; and a second duct fluidly coupled to the AMV and including a second inlet that is exterior to the engine compartment and is configured to receive atmospheric air; wherein: the AMV is configured to modulate air into the engine from the first duct and the second duct, when a temperature of air within the AMV is above the first threshold and the temperature of air within the second duct is below the first threshold, to lower the temperature of air entering the engine to below the first threshold.
US11338646B2	Device for distributing the coolant in an air-conditioning system of a motor vehicle A heat pump system for a motor vehicle comprises at least two heat exchangers 10, 12, through which, for heating and/or cooling the motor vehicle interior, a flow is conducted, and at least two coolant circulations 14, 16 separable from one another, of which at least one is connectable, independently of the other coolant circulation, with one, two or more heat exchangers 10, 12 such that through these, in the presence of a connection with two or more heat exchangers 10, 12, a flow is successively conducted and the other coolant circulation is connectable with at least one heat exchanger 10, 12.
US11338642B2	Vehicle cabin air conditioning system A vehicle cabin air conditioning system includes a cabin indoor air conditioner and an individual air conditioner configured to condition air in a target space inside a cabin. The individual air conditioner includes a blower, a heat generator, a supply port, and an exhaust port. The supply port supplies one of a cold air cooled with the heat generator and a warm air heated with the heat generator to the target space. The exhaust port provides the other of the cold air and the warm air to outside of the target space. The cabin indoor air conditioner includes a cabin blower, a temperature control unit, and a suction port through which air is sucked for the temperature control unit. An air flow path is provided to guide air sent from the exhaust port of the individual air conditioner to the suction port of the cabin indoor air conditioner.
US11338639B2	Damper with solenoid in piston rod A shock absorber includes: a pressure tube defining a working chamber; a piston assembly slidably disposed within the pressure tube, the piston assembly dividing the working chamber into a first and second chambers; a piston rod including a first end that is attached to the piston assembly and that includes a second end that is configured to be attached to one of a sprung mass and an unsprung mass of a vehicle; an electronic valve that is positioned within the piston rod, the electronic valve including a spool moveable between first and second positions, where: when the spool of the electronic valve is in the first position, the spool allows fluid flow between the first and second chambers through the electronic valve and the piston rod; and when the spool of the electronic valve is in the second position, the spool restricts fluid flow between the first and second chambers.
US11338638B2	Vehicle suspension having controllable ground clearance and rigidity The invention relates to a suspension for motor vehicles having controllable chassis clearance and stiffness, and includes a helical spring (1), having a controlling device (2) which is secured to the body of the vehicle and is located rotatably, preferably by means of a transmission stage driven by an electric motor. The controlling device (2) is embodied as a shaped nut, which is screwed directly onto the coils of the preferably cylindrical helical spring (1) and has roller bodies which are located along the helical line and are connected to coils of the helical spring; the controlling device (2) is fully movable and fixable onto and relative to the helical spring. The suspension for motor vehicles ensures enhanced stiffness of the suspension in the event of a decrease in the chassis clearance, reduced stiffness of the suspension when the chassis clearance is increased, and the possibility of building in a telescoping damper inside the helical spring without blocking access to its upper fastening point.
US11338636B2	X-shaped spring device for a motor vehicle wheel suspension system An X-shaped spring for a transportation vehicle wheel suspension system having, per wheel side, a first leaf spring and a second leaf spring made from fiber-reinforced arranged to lie above one another and combined at a respective first end on a first fastening device for transportation vehicle body-side support, wherein the first leaf spring has a second fastening device at its second end for wheel-side support, and the second leaf spring is supported at its second end on the transportation vehicle body side. Towards its second end, the second leaf spring is an arc section curved away from the first leaf spring.
US11338632B2	Inflation system for tubeless tires An inflation system for tubeless bicycle tires may include a valve, a sealant canister, a pump head, and/or a valve core adapter. The valve, sealant canister, and pump head may collectively facilitate sealant injection into a tire by a user. The valve has an external valve seat, and includes a valve body, a valve stem extending through the length of the valve body, and a retaining mechanism for the valve stem disposed interior to the valve body. The valve stem is configured to move relative to the valve body, such that a resilient seating surface disposed at a proximal end of the valve stem is displaced relative to a valve seat formed by an exterior surface of a proximal end of the valve body.
US11338625B2	Automatic tire inflation monitoring system Embodiments included herein are directed towards an automatic tire inflation monitoring system and method. The method may include confirming, using a battery powered electronic sensor, that there is no active tire re-inflation in progress. The method may further include monitoring, using the battery powered electronic sensor, the status of all tire pressures over a period of time and determining, using the battery powered electronic sensor, whether a rate of tire pressure reduction exceeds a first value. The method may include reporting, using the battery powered electronic sensor, a fault if the rate exceeds the first value.
US11338622B2	Run-flat tire A run-flat tire includes a side reinforcing rubber layer, a first bead filler on an inner side of a carcass turned-up portion in a width direction, and a second bead filler on an outer side of the carcass turned-up portion in the width direction. A first bead filler height is 30% or less of a tire cross-sectional height SH. A second bead filler height is 50% or greater of the height SH. A cross-sectional area of the second bead filler is from 150% to 400% of a cross-sectional area of the first bead filler. A relationship (0.16×SH×LI−1100)≤SALL≤(0.16×SH×LI−800) is satisfied, where SALL represents a sum of cross-sectional areas of the side reinforcing rubber layer and the first and second bead fillers, and LI represents a load index.
US11338618B2	Egg crate sidewall features for sipes The present invention includes tire treads having a plurality of sipes (14) where at least one of the opposing sides of the sipe thickness includes a plurality of projections (18, 36) and recesses (20, 38) and a method for forming the same.
US11338617B2	Vehicle recovery device A vehicle recovery device (10) comprising a first track (12) formed from a plurality of pivotally connected panels (14) and a second track (13) formed from a plurality of pivotally connected panels (14). The first and second tracks (12, 13) are moveable from a planar configuration, in which the first and second tracks (12, 13) are usable for vehicle recovery, to a folded configuration, in which the first and second tracks (12, 13) are connectable by connectors (22) to form side walls of a receptacle (11) in the shape of a polyhedron.
US11338615B2	Wheel disc brake assembly The invention at hand refers to a wheel disc brake assembly comprising a wheel rim, a coupler ring and an annular brake disc arranged in a concentric manner, wherein an outer surface of the coupler ring is connected to an inner surface of the wheel rim and an inner surface of the coupler ring is connected to an outer surface of the annular brake disc. The wheel disc brake assembly further comprises a caliper with at least two brake pads facing each other, wherein the caliper surrounds at least a part of the inner surface of the annular brake disc and the at least two brake pads are configured to press against opposite side faces of the annular brake disc.
US11338614B2	Wheel and rim with weight reduction sockets A wheel and a rim with weight reduction sockets are provided. The rim is made of an aluminum alloy and includes an inner flange, a middle portion and an outer flange, the inner flange, middle portion and outer flange are all annular and are connected end to end to form a cylindrical rim, in which weight reduction sockets are provided on the outer surface of the middle portion of the rim; the weight reduction sockets are rectangular ones, and are arranged in lattices in turn; and 3-5 rows of weight reduction sockets are arranged annularly on the outer surface of the middle portion of the rim.
US11338613B2	Wheel and rim with weight reduction sockets A wheel and a rim with weight reduction sockets are provided. The rim includes an inner flange, a middle portion and an outer flange, the inner flange, middle portion and outer flange are all annular and are connected end to end to form a cylindrical rim, in which the middle portion of the rim includes weight reduction sockets; and the weight reduction sockets are of regular hexagons, and are arranged adjacently on the outer side of the middle portion of the rim in the shape of a honeycomb. The weight of the hub is reduced by designing the weight reduction sockets in a specific shape for the outer rim of the hub and selecting the size of the weight reduction sockets.
US11338612B1	Wheel center cap assembly The invention concerns wheel center cap assemblies that include an adapter and a wheel center cap that registers with, or is integral with, the adapter. In some embodiments, the adapter includes tracks and lug sleeves that couple with lugs of the vehicle wheel. Each of the lug sleeves is slidably coupled to each of the tracks of the adapter, and each of the lug sleeves is adapted to move along a length of the tracks; this helps ensure that the adapter is universally compatible with multiple wheel models. In other embodiments, an adapter has a body adapted to be inserted within the center aperture of the wheel. A posterior support registers with the adapter and is sandwiched between a rotor of the vehicle and the wheel to secure the adapter inside the aperture of the wheel; a removable wheel center cap registers with the adapter to adorn the wheel.
US11338608B2	Tablet device for recording notes or markings in underwater or severe environment A tablet-like device is configured to have a slightly negative buoyancy and to hold a sheet of waterproof synthetic paper, or another removable, waterproof recording sheet, onto which notes or messages or sketches can be recorded via a writing implement, in an underwater or marine environment, or another extreme or severe environment. Since the tablet device is configured for use of sheets of waterproof synthetic paper, divers can work with their own personal pre-printed material underwater. Further, the tablet device also has the advantages of cost savings and reduced environmental impact.
US11338603B2	Liquid ink-receiving layers or films for direct ink jet printing or ink printing Liquid ink-receiving layers or films (receiving layers) for direct ink jet printing or ink printing, into which low-viscous liquid (highly fluid) printing media (printing inks) can be introduced according to said printing methods, and which solidify or are able to be solidified at a time subsequent to the ink insertion (retarded). The invention eliminates limitations on the usability of raw materials for ink jet printing or ink printing, especially of film-forming agents but also of pigments and other ingredients. Moreover, corresponding compositions and methods for ink jet printing or ink printing are proposed.
US11338600B2	Recording device and recording method A recording device includes a recording head in which a plurality of nozzle rows are arranged in a predetermined direction that include a first nozzle row including a plurality of nozzles for ejecting ink having a predetermined color, and a second nozzle row including a plurality of nozzles for ejecting ink having an identical color to the predetermined color, and a control unit configured to control ejection of ink by the nozzle, wherein the control unit, when a test pattern for an inspection of a missing dot due to an ejecting defect of the nozzle is recorded on a recording medium, records a dot pattern, that is an individual element that forms the test pattern, so that ink ejected from a nozzle of the first nozzle row, and ink ejected from a nozzle of the second nozzle row overlap.
US11338599B2	Moving body support apparatus and printing apparatus A moving body support apparatus including a main shaft, a sub-shaft that is arranged to be spaced from the main shaft, and a carriage that moves along the main shaft while causing a contact surface to be in contact with the sub-shaft is provided. A distance between the main shaft and the sub-shaft changes along a moving direction of the moving body. A printing apparatus including the moving body support apparatus is also provided.
US11338598B2	Cartridge Disclosed is a cartridge installed in a tape printing device, the cartridge including: a tape path through which a printing tape introduced from a device-side tape introduction port is fed toward a device-side tape ejection port in a state in which the cartridge is installed in a cartridge installation part; and a tape retention part that retains the printing tape introduced into a tape path in a state in which the cartridge is not installed in the cartridge installation part, wherein, when the cartridge is installed in the cartridge installation part, the tape retention part engages an insertion convex part that protrudes from a bottom surface of the cartridge installation part to cancel retention of the printing tape.
US11338593B1	Method for controlling the movement of transparent media during final curing to minimize print head degradation A method is disclosed for reducing the scatter of UV light during a final curing operation in the three-dimensional printing on the surface of transparent and semi-transparent media. The method precisely controls the movement of media during a final cure step in the printing of an expressed inkjet image on the surface of transparent media. The method also controls a number of factors during final curing operation such as the lateral movement of media under a final cure lamp, the number of rotations that media undergoes during final curing, the timely modulation of UV lamp power during final curing, and the selection of UV emitter segments positioned away from a inkjet print head to reduce the amount of potential UV radiation from impinging upon one or more of the adjacent printing heads.
US11338592B2	Image recording method and image recording system An image recording method includes determining whether a surface energy of a base material is less than 50 mN/m or greater than 50 mN/m; deciding a condition for drying a pretreatment liquid containing water and an aggregating agent as a condition A in which the mass ratio of the mass of the pretreatment liquid after being dried to the mass of the pretreatment liquid before being dried is 30% or greater and deciding a condition for drying the pretreatment liquid as a condition B in which the mass ratio thereof is less than 50% in a case where the surface energy is determined to be less than 50 mN/m and 50 mN/m or greater, respectively; applying the pretreatment liquid to the base material; drying the applied pretreatment liquid under the drying condition decided; and applying an ink containing water and a colorant to at least a part of the base material.
US11338591B1	Defective nozzle correction mechanism A printing system is disclosed. The printing system includes at least one physical memory device to store nozzle correction logic and one or more processors coupled with at least one physical memory device to execute the nozzle correction logic to receive a uniformity compensated transfer function for each of a plurality of pel forming elements, receive an average missing neighbor transfer function, receive a defective nozzles list including one or more of the plurality of pel forming elements indicated as defective during print production; and perform missing neighbor processing by applying the average missing neighbor transfer function associated with the pel forming element determined to be a neighbor of a defective pel forming element.
US11338590B2	Recording condition determining method and recording device A recording condition determining method is executed by a recording device performing recording by a main scanning and a sub scanning. The method includes a patch recording step of recording patches onto a recording medium by the overlap-processing in which the main scanning is performed on a partial region of the recording medium in an overlapping manner a plurality of times, the patch recording step including recording the patches at a plurality of different positions in a main scanning direction by a plurality of types of the overlap-processing under respectively different recording conditions. The method further includes a selection accepting step of accepting selection of a patch from among a plurality of the recorded patches, and a determination step of determining, as the recording condition of the overlap-processing of an actual recording, the recording condition of the overlap-processing associated with the patch selected in the selection accepting step.
US11338584B2	Liquid ejection apparatus Provided is a liquid ejection apparatus which, in a case of performing wiping operations at a plurality of different wiping pressures, can perform each wiping operation at a suitable wiping pressure and a suitable angle. To achieve this object, a liquid ejection apparatus is configured such that the angle of the wiping surface of a wiper to an ejection port surface can be changed while the wiper is out of contact with the ejection port surface and is not performing wiping, and the ejection port surface can be wiped with the wiper after the wiping surface angle is changed.
US11338583B2	Liquid ejecting head and liquid ejecting apparatus A liquid ejecting head includes a first individual flow path and a second individual flow path that are adjacent to each other, a first common liquid chamber and a second common liquid chamber. In the first individual flow path, a first communication flow path extending between the first common liquid chamber and a first nozzle, and an inertance of the first communication flow path is smaller than an inertance of a second communication flow path extending between the second common liquid chamber and the first nozzle. In the second individual flow path, a third communication flow path extending between the second common liquid chamber and a second nozzle, and an inertance of the third communication flow path is smaller than an inertance of a fourth communication flow path extending between the first common liquid chamber and the second nozzle.
US11338582B2	Liquid discharge apparatus and image recording apparatus including the same There is provided a liquid discharge apparatus configured to discharge a liquid, including a channel member for the liquid. The channel member is formed to include: individual channels; a first and second manifold channels; and a bypass channel. Each of the individual channels and the bypass channel are all connected to the first manifold channel on only one of an upper and lower sides of a central portion between upper and lower surfaces of the first manifold channel, and connected to the second manifold channel on only one of upper and lower sides of a central portion between upper and lower surfaces of the second manifold channel. A channel resistance of the bypass channel is smaller than that of the individual channels.
US11338581B2	Element substrate, liquid discharge head, and printing apparatus To suppress the progress of metal dissolution by ink when wire break of a wiring to a heater occurs, in an element substrate, according to the present invention, for example, which is used in an inkjet printhead, each of heaters integrated in the element substrate is connected to an individual wiring via a first through-hole penetrating an insulation layer, and further connected to a common wiring from the individual wiring via a wiring formed in another wiring layer via a second through-hole penetrating an insulation layer. The individual wiring and the common wiring are formed in the same wiring layer, and an aspect ratio of the second through-hole is lower than an aspect ratio of the first through-hole.
US11338574B2	Liquid ejecting apparatus and method for controlling liquid ejecting apparatus A liquid ejecting apparatus includes a first pressure chamber communicating with a first nozzle configured to eject a liquid, a second pressure chamber adjacent to the first pressure chamber and communicating with a second nozzle configured to eject the liquid, and a first driving element corresponding to the first pressure chamber. The liquid ejecting apparatus executes a detection operation of detecting a fluctuation in the pressure of the liquid within the second pressure chamber that occurred when the first driving element was driven to cause the pressure of the liquid within the first pressure chamber to fluctuate.
US11338571B2	Method for cleaning a printing fluid off a surface of at least one rotatable component of a printing machine A method for cleaning a printing fluid off a surface of at least one rotatable component of a printing press includes selecting and executing one of a plurality of predefined cleaning operations in an automated way. The selection is made on the basis of a predefined mathematical model executed on a computer and, when the model is executed, a parameter corresponding to an amount of the printing fluid present on the surface is calculated. The improved cleaning method may be applied in all modes of operation of the printing press and in particular allows detergent, cleaning cloth, and/or water to be saved.
US11338570B2	Sheet detection circuit using electrical elements contacting conductive vacuum belt Devices include electrically conductive elements contacting a vacuum belt, and a voltage source connected to the electrically conductive elements. The electrically conductive elements form an electrical circuit from the voltage source, through the belt, and back to the voltage source. The electrically conductive elements are positioned so that they are separated from the belt when the belt moves the sheets of media between the electrically conductive elements and the belt. A processor is capable of identifying leading edges of the sheets of media on the belt (when voltage of the electrical circuit changes from a relatively higher voltage to a relatively lower voltage) and identifying trailing edges of the sheets of media on the belt (when the voltage of the electrical circuit changes from the relatively lower voltage back to the relatively higher voltage).
US11338569B2	Screen printing device having a screen printing stencil A screen printing device has a screen printing stencil. At least two doctor blade systems, each acting on the screen printing stencil are provided. The at least two doctor blade systems are arranged to each apply printing ink to an object to be printed in the same printing process. Each of the doctor blade systems has at least one doctor blade. Each of the doctor blades is arranged to sweep over the screen printing stencil. Each of the doctor blade systems is individually controlled by a control unit. The at least one doctor blade of each of the doctor blade systems is moved by a robot. At least respective two-dimensional motion paths of the doctor blades of each doctor blade system are each freely programmed and are established by control of the robot.
US11338567B2	Paper feed and biasing system and method for stapler unit A finisher assembly of a multifunction peripheral includes a vertically oriented stapler and a paper transport motor. When the paper transport motor rotates in the forward direction, printed pages from the print engine of the multifunction peripheral are received via a paper chute and a feed assist roller urges the printed pages into a vertical paper accumulation cache basin. Rotation of the paper transport motor also opens a biasing plate allowing the pages to freely enter the cache basin. Once all of the pages of the print job are in the cache basin, the paper transport motor rotates in the reverse direction causing the biasing plate to bias the printed pages, in the cache basin, against a registration surface of the vertically oriented stapler unit. The pages of the print job are stapled together the stapled print job is moved to the paper tray for collection by a user.
US11338562B2	Antifogging laminate It is a main object of the present invention to impart higher antifogging properties to the hydrophilic material formed of a crosslinked resin, having a surface enriched with hydrophilic groups, previously proposed by the inventors. The laminate of the present invention includes a water absorbing layer (B) and a hydrophilic layer (A) provided in this order on a substrate, wherein the hydrophilic layer (A) is formed of a crosslinked resin having an anionic, cationic or nonionic hydrophilic group, and has a gradient of hydrophilic groups (intensity of hydrophilic group on surface of the hydrophilic layer (A)/intensity of hydrophilic group at ½ of thickness of the hydrophilic layer (A)) of not less than 1.1; and the water absorbing layer (B) is formed of a crosslinked resin having a water absorption rate per unit mass (g) of in the range of 5 to 500 wt %.
US11338561B2	Oriented polypropylene film with improved blocking resistance The present disclosure is directed to a film formulation that resulted in a substantially non-migratory cold seal release film with improved blocking resistance. Specifically, the multilayered biaxially oriented polypropylene film can include a core layer of polypropylene homopolymer; a first outer layer on one side of the core layer that can be suitable for sealing, printing, or coating; and a second outer layer on the opposite side of the core layer that is a blocking resistant layer comprising thermoplastic polymers which reduce blocking tendency.
US11338559B2	Polyolefin based films with matte surface and improved sealing performance Embodiments of the present disclosure are directed to multilayer films, which provide matte appearance and low heat seal initiation temperature after corona treatment. The multilayer films include at least one matte layer comprising ethylene-based polymer and propylene-ethylene copolymer.
US11338556B2	Laminating thin strengthened glass to curved molded plastic surface for decorative and display cover application A process comprises cold-forming a flat glass substrate into a non-planar shape using a die. The cold-formed glass substrate is bonded to a non-planar rigid support structure at a plurality of non-planar points using the die. Bonding methods include injection molding the non-planar rigid support structure, and direct bonding. An article is also provided, comprising a cold-formed glass substrate having opposing major surfaces and a curved shape, the opposing major surfaces comprising a surface stress that differ from one another. The cold-formed glass substrate is attached to a rigid support structure having the curved shape. The cold-formed glass substrate includes an open region not in direct contact with the non-planar rigid support structure, and the open region has a curved shape maintained by the non-planar rigid support structure.
US11338551B2	Hot-dip galvanized steel sheet having excellent low-temperature adhesion and workability Provided is a hot-dip galvanized steel sheet having excellent low-temperature adhesion and workability, and a manufacturing method therefor, the hot-dip galvanized steel sheet comprising: an inhibition layer formed on a base steel sheet and comprising an Fe—Al-based intermetallic alloy phase; a hot-dip galvanized layer formed on the inhibition layer; and an Al—Mn-based alloy phase discontinuously formed between the inhibition layer and the hot-dip galvanized layer.
US11338550B2	Hot-stamped body There is provided a hot-stamped body including: a steel base metal; and a metallic layer formed on a surface of the steel base metal, wherein the metallic layer includes: an interface layer that contains, in mass %, Al: 30.0 to 36.0%, has a thickness of 100 nm to 5 μm, and is located in an interface between the metallic layer and the steel base metal; and a principal layer that includes coexisting MgZn2 phases and insular FeAl2 phases, is located on the interface layer, and has a thickness of 3 μm to 40 μm.
US11338549B2	Steel sheet for hot press formed member having excellent resistance to hydrogen delayed fracture and method for manufacturing thereof Provided is a steel sheet for a hot press formed member having excellent resistance to hydrogen delayed fracture, and a method for manufacturing the same. A steel sheet for a hot press formed member comprises: a base steel sheet; an aluminum alloy plating layer on a surface of the base steel sheet; and an oxide layer which is formed on a surface of the plating layer and has a thickness of 0.05 μm or more.
US11338542B2	Composite sidewall and cargo body having same A composite molded cargo body panel including a core, an interior skin secured to a first side of the core having a thickness, and exterior skin secured to a second side of the core, and a plurality of recesses. The plurality of recesses are dispersed along a first direction at intervals in the interior skin, with the core thickness at each of the plurality of recesses being reduced compared to a maximum core thickness, and each of the plurality of recesses defines a support surface. A pocket is formed in each of the plurality of recesses, with the core thickness at the pocket being less than the core thickness at each of the plurality of recesses. A plurality of logistics inserts are attached to the respective support surfaces of the plurality of recesses so that, at each of the plurality of recesses, the logistics insert extends across the pocket.
US11338541B2	Multilayer tubular structure intended for transporting an air-conditioning fluid A multilayer tubular structure intended for transporting a heat-transfer fluid, the multilayer tubular structure including: a first layer including at least one long-chain polyamide having between 10 and 15 carbon atoms per nitrogen atom and including at least 50% aliphatic units relative to the sum of the units present in the long-chain polyamide; a second layer including at least one polyamide having between 4 and 9 carbon atoms per nitrogen atom, the polyamide including at least 50% aliphatic units relative to the sum of the units present in the polyamide; an optional layer, the first layer containing no continuous fibres, the second layer being in contact with the transported fluid when an optional layer is not present, and the layer or layers representing at least 50% of the total thickness of the tube.
US11338536B2	Box opening device A box-opening device is disclosed. The box-opening device includes a first holding part that holds a first surface and a second holding part that holds a second surface. The first surface is one of two adjacent surfaces of a folded corrugated cardboard sheet, and the second surface is the other of the two adjacent surfaces of the corrugated cardboard sheet. The box-opening device also includes a first holding part movement mechanism which changes a position of the first holding part with respect to the second holding part and thereby transforms the corrugated cardboard sheet into an opened state. The first holding part movement mechanism has a support member that supports the first holding part so that the part rotates on an arc track about a central axis of rotation that overlaps an imaginary line extending along a boundary line between the first surface and the second surface.
US11338535B2	Sheet folding device and method, and box-making machine A sheet folding device and method, and a box-making machine, wherein are provided a molding belt for moving on a center side in the width direction of a cardboard sheet toward a downstream side in a transfer direction of the cardboard sheet and thereby pressing and folding both end parts in the width direction of the cardboard sheet from the outside, and a folding roller group formed by folding rollers for contacting insides of fold parts on both sides in the width direction of the cardboard sheet more toward the center in the width direction of the cardboard sheet than the molding belt, the folding rollers being arranged further upstream in the transfer direction of the cardboard sheet than a 90-degree folding position of the cardboard sheet.
US11338534B2	Cutting unit, web of packaging material, and method for cutting preparation features into it A cutting unit for cutting preparation features in a web of sheetlike material is provided. The cutting unit has a first part with a rigid base portion, at least one first cutting tool configured to cut a first preparation feature in the web of sheetlike material, and at least one second cutting tool configured to cut a second preparation feature in the web of sheetlike material. The at least one first and second cutting tools are attached to the base portion and located at a distance from each other, wherein at least one of the at least one first or second cutting tools is supported by a flexible support that is located in the rigid base portion of the first part.
US11338533B2	Dynamically adjustable sensors for trash compactors and receptacles Systems, methods, and computer-readable storage media for dynamically adjusting sensors for use in compactors and receptacles. A receptacle first sends a signal from a transmitter on a first module in a receptacle to a receiver on a second module in the receptacle, wherein the first module is located on a first inner wall of the receptacle and the second module is located on a second inner wall of the receptacle, and wherein at least part of the first module and the second module is located a distance above a bin inside the receptacle. Next, the receptacle determines a signal-detection characteristic including a signal detection status or a number of signal pulses associated with a signal detection. Based on the signal-detection characteristic, the receptacle determines an operating condition of the receptacle, the operating condition including a fullness level or an obstruction level associated with the first or second sensors.
US11338532B2	Device and method for separating materials with different degrees of flowability An apparatus for separating materials with different flowability has a rotationally driven hollow drum with a perforated peripheral surface, stripping means for stripping away material, and a continuous compression belt pressed from outside onto the drum by wrapping around part of the circumference of the drum, an intake wedge for the material. The belt is mounted by a drive roller and bearing roller. The drive roller controllably variably presses into a pressing position against the drum, separated by the belt. The drive roller position is adjustably set by a first positioning device via a control device, with a first end abutment element for mechanical position limitation. Part of the first positioning device comes into blocking contact with a first counter-surface of the first end abutment element in the pressing position of the drive roller and the first counter-surface of the first end abutment element is adjustable by the control device.
US11338523B2	System and method for operating a multi-nozzle extruder during additive manufacturing An additive manufacturing system has a controller configured to modify numerical control programming instructions to form interlocking structures that improve object structural integrity in the Z-direction. The interlocking structures are produced by forming one layer with swaths that are separated by gaps and another layer that is formed over the gaps to fill the gaps and lay over the swaths forming the gaps.
US11338522B2	Method for calibrating an apparatus for producing an object by means of additive manufacturing The invention relates to a method for calibrating an apparatus for producing an object by means of additive manufacturing. The apparatus comprises a process chamber, as well as a support for positioning the object in relation to a surface level of a bath of material to be solidified. A solidifying device is arranged for emitting a beam of radiation on the surface level for solidifying a selective part of said material. The solidifying device comprises a focus member for adjusting a focus setting. The method according to the invention comprises the steps of controlling the solidifying device for making test patterns at different focus settings. A calibration system with a sensor unit is used for determining characteristics of test patterns, and a calibrated focus setting is determined based on the characteristics.
US11338521B2	Parts packing for a build volume In an example of a method for parts packing, at least one part to be printed is identified. A placement and an orientation of the at least one identified part in a build volume of a three-dimensional (3D) printer is determined that optimizes a thermal uniformity inside the build volume.
US11338519B2	Devices, systems, and methods for monitoring a powder layer in additive manufacturing processes Devices, systems, and methods for monitoring a powder layer in additive manufacturing are disclosed. A method includes receiving leading and trailing image data from an image signal processor that is optically coupled to a plurality of leading and trailing optical fibers arranged on a moving powder distributor, the leading and trailing image data corresponding to images of the powder layer, selecting at least one point on the powder bed that is located within a leading region of interest, determining first characteristics of the point, when the point is located within a trailing region of interest due to movement of the moving powder distributor, determining second characteristics of the point, and comparing the first characteristics to the second characteristics to monitor the powder layer distributed by the moving powder distributor.
US11338515B2	Self-rotation cleaning device and device for cleaning photo-cured tissue engineering scaffold A self-rotation cleaning device has outer and inner housings, a workpiece rotating system, an ultrasonic cleaning system and a fluid perfusion system. The inner housing is in the outer housing in a horizontal direction. A cylindrical cavity is inside the inner housing. One end of the inner housing has a sealing cover detachably connected thereto, and the other end is closed. The workpiece rotating system is in the cavity for fixing a member to be cleaned, and realizes self-rotation of the member. The ultrasonic cleaning system supplies mechanical energy to the cleaning liquid in the inner housing to generate bubbles therein. The bubbles remove residual resin attached to the cleaned member surface by continuous vibration and burst. The fluid perfusion system provides self-rotation power for the cleaned member, and continuously delivers the cleaning liquid to the inside of the cleaned member, and the cleaning liquid is carried out after cleaning.
US11338513B2	Plant for additively manufacturing at least one three-dimensional object Plant for additively manufacturing at least one three-dimensional object, comprising at least one process station for an additive manufacturing process, wherein at least one functional component, preferably a lifting device for a powder module, of the process station is at least partially enclosed by a housing structure of the process station, wherein the process station is coupled or can be coupled with at least one powder module, wherein the housing structure comprises at least one opening for loading and/or unloading the at least one powder module into or from the process station, wherein a platform is provided that is arrangeable or arranged adjacent to the at least one opening, wherein the platform comprises at least one positioning unit with at least one positioning surface for positioning a module carrier which is adapted to carry the at least one powder module.
US11338510B2	Build material distributing cylinders A three-dimensional (3D) printing device includes a first cylinder. The first cylinder may include a first plurality of holes defined therein. The 3D printing device may include a second cylinder interior and coaxial to the first cylinder that includes a second plurality of holes open to an interior of the first cylinder. The 3D printing device may also include a third cylinder interior to the first cylinder and exterior to the second cylinder, the third cylinder including a longitudinal cutout open to the first cylinder. The 3D printing device may include a supply tube open to the second cylinder, the supply tube to provide an amount of build material to an interior portion of the second cylinder.
US11338507B2	Coalescing agent concentrations and contone densities for three-dimensional objects In some examples, at least one agent distributor may be to selectively deliver mixtures of coalescing agent and carrier onto portions of a layer of build material at variable coalescing agent concentrations and variable contone densities. A controller may be to control the at least one agent distributor to selectively deliver the mixture to a portion of the layer at a selected coalescing agent concentration and a selected contone density.
US11338506B2	Lamination molding apparatus A lamination molding apparatus includes a chamber that covers a molding region, an irradiator that irradiates a material layer formed in the molding region with a laser beam or an electron beam and forms a solidified layer, a supply port that supplies an inert gas to the chamber, a discharge port that discharges the inert gas from the chamber, an inert gas supplier which is connected to the supply port and supplies the inert gas to the chamber, a fume collector, and an oxygen concentration adjustor. The fume collector has an inlet, a charging section, a collecting section, and an outlet. The oxygen concentration adjustor is connected between the discharge port and the charging section and supplies, to the fume collector, an adjusting gas having an oxygen concentration higher than an oxygen concentration of the inert gas which is discharged from the discharge port.
US11338499B2	Substrate A substrate and a method for producing the same are disclosed herein. In some embodiments, a substrate includes a base layer, a black layer formed on the base layer, and column spacers formed on the black layer, wherein a loss rate of spacers measured by a peel test is 15% or less. The substrate can have excellent adhesiveness of the spacer to the base layer or the black layer and ensuring appropriate darkening properties. The method can effectively produce such a substrate without adverse effects such as occurrence of foreign materials without separate treatment such as heat treatment.
US11338497B2	Systems and methods for thermoforming thermoplastic structures A system for forming a thermoplastic may comprise a mandrel configured to receive a thermoplastic charge. The mandrel may rotate about a mandrel axis. A series of rollers may be located circumferentially about the mandrel and configured to apply radially inward pressure. A heating element may be located upstream of the series of rollers.
US11338496B2	Method and device for producing containers from thermoplastic material The invention relates to a method for producing containers (14) from preforms (12) made of thermoplastic material by means of a blow molding machine (10) comprising at least one temperature control device (26) and one forming device having at least two forming stations (16), wherein the preforms (12) are temperature controlled by means of the temperature control device (26) on the basis of specifiable first control parameters, and wherein one temperature-controlled preform (12) is formed by means of one of the forming stations (16), respectively, on the basis of specifiable second control parameters into a container (14), wherein at least one of the second control parameters is individually specified for each of the forming stations (16). The invention furthermore relates to a blow molding machine (10), designed for executing the method according to the invention, for producing containers (14) from preforms (12) made of thermoplastic material.
US11338491B2	Control apparatus for producing and/or handling a plastic film An improved control apparatus for producing plastic films and an associated improved method are distinguished, inter alia, by the following features: —the control apparatus has two stages or at least two stages, —the control apparatus comprises, for this purpose, a sensor module and/or a sensor model and a process module and/or a process model, —the machine-dependent sensor module and/or sensor model and the production-dependent process module and/or process model are linked or can be linked to one another via production variables, —adjustable machine variables are connected or linked to plant production variables via the sensor module and/or the sensor model.
US11338487B2	Slide piece driving mechanism A slide piece driving mechanism includes a side surface guiding portion, a shaft portion, and stopper releasing element. The side surface guiding portion is disposed at a movable side mold to guide a side surface of a slide piece to be slidably movable. The shaft portion of a stopper is disposed at the side surface guiding portion. When the slide piece reaches an upper end position, the shaft portion engages with a stopper hole of the slide piece to prevent the slide piece from falling from the upper end position due to own weight. The stopper releasing element releases the engagement of the shaft portion of the stopper with the stopper hole to allow the slide piece from falling from the upper end position due to its own weight.
US11338484B2	Member joining method A member joining method includes: a placement process of arranging a first member and a second member inserted into the first member so that a gap surrounding the second member is provided between the first member and the second member; a filling process of filling a molten resin into the gap and applying pressure to the resin so as to cause at least one member of the first member or the second member to undergo elastic deformation; and a pressure maintaining process of maintaining the pressure until the resin that has been filled into the gap has cured.
US11338483B2	Passive horn integrally formed by using thermoplastic vulcanized rubber and preparation method thereof A passive horn integrally formed using thermoplastic vulcanized rubber includes a first outer casing, a second outer casing, an inner casing and an iron piece. The first outer casing includes a sealing ring, a folding ring and a vibrating membrane, and the sealing ring, the folding ring and the vibrating membrane are integrally injection molded into the first outer casing. A groove is disposed in the second outer casing, and the first outer casing is disposed in the groove. The back surface of the vibrating membrane is provided with a casing groove sequentially embedded with the inner casing and the iron piece. Furthermore, a preparation method of a passive horn integrally formed using thermoplastic vulcanized rubber, which, under the condition of integrated injection molding, may improve the yield rate, ensure product quality, save assembly time and labor cost, and improve production efficiency.
US11338482B2	Resin molding device and method A movable mold includes a main mold part, a separate mold part separate from the main mold part, and a relative movement mechanism moving the separate mold part relative to the main mold part in a driving direction of a mold driver.
US11338480B2	Apparatus and method for emulating temperature during a thermal cure cycle A method including steps of (1) heating, with a heating system, an apparatus comprising an enclosure assembly and a temperature emulation assembly positioned within said enclosure assembly; (2) thermally isolating said temperature emulation assembly from said heating system with said enclosure assembly; (3) permitting conductive heat transfer to said temperature emulation assembly only through an enclosure assembly-leading end of said enclosure assembly; and (4) representing a hottest temperature and a coldest temperature of an article being emulated by said apparatus with said temperature emulation assembly.
US11338479B2	Autoclave, autoclave system, and method for curing a part Disclosed here is an autoclave system for curing a part. The autoclave includes a gas recirculation system, at least partially external to a vessel pf the autoclave system and fluidly coupleable to the vessel such that gas contained in the vessel is delivered to the gas recirculation system, passed through the gas recirculation system, and recirculated back into the vessel. The autoclave system also comprises at least one mold core, located within the vessel. The mold core comprises a conduit extending through the mold core and the mold core is configured to define a shape of the part. The gas delivered to the gas recirculation system from the vessel is gas received directly from the conduit of the mold core.
US11338478B2	Undercut processing mechanism, molding die, and molded product An undercut processing mechanism is attached to and used in a molding die for forming a molded product having an undercut portion, and allows demolding of the undercut portion. The undercut processing mechanism includes: a holder attached to or formed integrally with the molding die; a sliding piece configured to be slidable relative to the holder such that a mold core is moved so as to demold the undercut portion; a retaining piece configured to retain the sliding piece such that the sliding piece is slidable; and a support wall configured to support the sliding piece so as to prevent the sliding piece from being tilted when the sliding piece slides. The sliding piece forms a part of the mold core for forming the undercut portion.
US11338475B2	Fiber-reinforced resin composition A fiber-reinforced resin composition contains a resin-adhered long fiber bundle including composition (A), a thermoplastic resin, and component (B), a rayon fiber, wherein the rayon fiber of component (B) satisfies the following requirements (b1), (b2) and (b3), and the resin-adhered long fiber bundle is obtained by adhering and integrating the thermoplastic resin of component (A) in a molten state to and with a strand of longitudinally-arranged rayon fibers of component (B), and cutting the strand into a length of 3 to 30 mm, (b1) a fiber diameter of 5 to 30 μm; (b2) a tensile elongation of 10% or more; and (b3) a flat shape with a ratio between a major axis length and a minor axis length (major axis length/minor axis length) in a width-directional cross-section of 1.1 or more.
US11338474B2	Injection molding method An injection molding method uses a die with a cavity into which molten resin is to be injected to fill the cavity. The die has a shape that causes the molten resin injected into the cavity to branch and merge. The injection molding method includes providing bubbles into the molten resin before the molten resin is injected, generating fine bubbles with the provided bubbles before the molten resin is injected, injecting the molten resin containing the fine bubbles, and bursting the fine bubbles of the injected molten resin containing the fine bubbles in a merging location where the molten resin merges.
US11338471B2	Sheet manufacturing apparatus A sheet manufacturing apparatus includes a coarse crushing portion that crushes a raw material containing a fiber into coarse crushed pieces, a defibrating portion that defibrates the coarse crushed pieces into a defibrated material, a sieve portion that includes a plurality of openings, a sheet forming portion that uses the defibrated material passing through the opening of the sieve portion to form a sheet, and a transport passage that transports the defibrated material, which has not passed through the opening of the sieve portion, between the coarse crushing portion and the defibrating portion.
US11338469B2	Interchangeable debarking rings apparatus and method The present invention is a debarking ring apparatus to prevent operational downtime of logs debarking by having two debarking rings placed on the same vertical plan, perpendicular to the flow of incoming and outgoing logs, and parallel to each other. Only one ring may be operational at a time. As such, maintenance may be done on one of the rings while the other is in operation. Debarking rings may have varying sizes and shapes independent from each other. Each debarking ring may further have its own frame, actuator and control and motorization modules. A sliding system, supported by a frame, may further direct the lateral displacement of both rings. Also presented is a method of processing logs through the debarking ring apparatus.
US11338466B2	Arrangement for replacing a saw chain on a motor saw The present invention refers to a motor saw arrangement comprising a support plate attached to the motor saw chassis or motor saw motor, a detachable clamping plate and a detachable guide bar arranged between the support plate and the clamping plate. The support plate is provided with two first recesses and at least one threaded hole, while the clamping plate is provided with two protrusions adapted to fit inside the respective two first recesses when the clamping plates is attached to the support plate and the protrusions each have a height that exceeds a corresponding height of the guide bar. The guide bar is provided with two keyhole-shaped slots and with a longitudinal slit between the two keyhole-shaped slots and the support plate is further provided with an alignment means. The invention further relates to a method to remove and/or replace a saw chain from a guide bar and to a guide bar intended and adapted for the motor saw arrangement described herein.
US11338456B2	TrimSafe histology radius blade grossing knife A histology radius blade grossing knife is provided. The histology radius blade grossing knife has a blade mounting system adapted to operatively retain a histology radius trimming blade. The blade mounting system provides a retaining spine for engaging an upper edge of the trimming blade, wherein a rear portion of the retaining spine is securely sandwiched by retaining plates of the blade mounting system. Furthermore, the trimming blade provides notches and/or recesses for facilitating such operative association. Each histology radius trimming blade embodies a radiused or otherwise uniquely shaped heel for cutting and dissecting tissue.
US11338455B1	Adaptive dress pack manager for robotic arm A dress pack manager for use with a robotic arm having an end-of-arm tool supplied with power or working fluid via a dress pack. A pair of rollers are spaced apart such that the dress pack may pass between them, and such that rotation of the rollers applies friction to the dress pack and causes the dress pack to move. An electric motor rotates one of the rollers in both a forward and backward rotation and is torque-controlled to maintain a constant tension applied to the dress pack by the rollers.
US11338454B2	Holding arm for positioning a medical instrument or a medical appliance A segment of a holding arm for positioning a medical instrument or a medical appliance including several node structures, and a strut that rigidly connects two of the several node structures to each other. The strut includes flat structures that are joined to one another.
US11338452B2	Robot hand including a plurality of grippers and a method of handling a wire harness using a robot hand A method of handling a wire harness that can automate a task of picking up and transporting the wire harness including a plurality of connectors and a wire member by gripping the plurality of connectors. In the method, positions of the plurality of connectors of the wire harness being placed apart from the robot hand are acquired, the robot hand is positioned such that the first connector is in the range of the first gripper based on the acquired position of the first connector, the first gripper is moved and the first connector is gripped and picked up by the first gripper, then, the robot hand is positioned such that the second connector is in the motion range of the second gripper based on the acquired position of the second connector, and the second gripper is moved and the second connector is gripped and picked up by the second gripper.
US11338445B2	End effector force sensor and manual actuation assistance An automated positioning system and methods of controlling the same. The positioning system includes a multi-joint positioning arm, an end effector coupled to a distal end of the positioning arm, a force-moment sensor (FMS) coupled to the end effector and a controller coupled to communicate with the positioning arm and the FMS. Using signals from the FMS, at least one external force or torque applied to the end effector is determined. A drive velocity for moving the end effector is determined, based on the at least one external force or torque. One or more joint movements of the positioning arm for moving the end effector is calculated, according to the drive velocity. The positioning arm is moved according to the one or more calculated joint movements.
US11338434B2	Controlling process of robots having a behavior tree architecture The present invention relates to a method for controlling a robot, the method including usage of a behavior tree architecture for tasks performed by the robot. The present invention also relates to a system comprising a data processing means adapted to carry out the method, wherein the system preferably comprises a robot. The present invention also relates to a use of a behavior tree architecture for programming, supervision, introspection and/or debugging.
US11338431B2	Robot A robot includes first and second arms to rotate and convey an object; a first rotary body to support the first arm and having a first fluid passage and at least one second fluid passage communicating with the first fluid passage; a base-end-side arm formed with an internal space and a hole part into which a part of the first rotary body is inserted; a second rotary body to support the second arm and having a third fluid passage communicating at one end thereof with the second fluid passage and communicating at the other end thereof with the internal space; a supplying device disposed in the internal space and connected to an upstream-end side of the first fluid passage, and to supply fluid to the first fluid passage; a first motor to rotate the first rotary body; and a second motor to rotate the second rotary body.
US11338429B2	Robot Disclosed is a robot including a microphone configured to acquire a voice, a camera configured to acquire a first image including a gesture, and a controller configured to recognize the acquired voice, recognize a pointed position corresponding to the gesture included in the first image, control the camera to acquire a second image including the recognized pointed position, identify a pointed target included in the second image, and perform a control operation on the basis of the identified pointed target and a command included in the recognized voice.
US11338427B2	Power tool A power tool is supportable by a lanyard. The power tool includes a motor housing, a motor arranged in the motor housing, front housing, an output member extending from the front housing, a gear case, and a gear train arranged in the gear case. The gear train is configured to transfer torque from the motor to the output member. The power tool also includes a first fastener securing the front housing to the motor housing, and a bracket fastened to one of the front housing, the motor housing, or the gear case by a second fastener that does not secure the front housing to the motor housing. The power tool also includes a support member secured to the one of the front housing, the motor housing, or the gear case by the bracket. The support member is attachable to the lanyard.
US11338425B2	Control method and dust extraction module Control method for a dust extraction module (2) for a chiseling tool (5), including the following steps: using a fan (18) of the dust extraction module (2) to draw in an air flow Q from a certain place of a substrate (31) being worked by the tool (5), using a material detector (24) to identify the material M at the place of the substrate being worked by the tool (5), and adapting the suction power of the dust extraction module (2) as a function of the identified material M in order to set the air flow Q. The air flow Q is greater than or equal to a rated value Qo in the case of an iron-free mineral material M1, whereas the air flow Q is less than the rated value Qo in the case of a material M2 containing iron.
US11338422B2	Driving tool A driving tool includes a main body, a trigger, a contact member and a control unit. The main body has a combustion chamber configured to be filled with fuel and compressed air. The trigger is configured to operate an ignition device to combust a mixture of the fuel and the compressed air filled in the combustion chamber. The contact member is brought into contact with a driving target member to enable an operation of the trigger. The control unit is configured to start an injection of the fuel when the contact member is turned on, and to complete an injection of the air after the trigger is turned on.
US11338420B2	Powder actuated nail gun A powder actuated nail gun includes a body, a trigger unit, a nose assembly. The body includes a first tube and a second tube. A room is defined in the second tube. The nose assembly includes a nose, two balls, two pressing members, two resilient members, and a collar. The nose includes a base, a tubular portion and a passage. The base includes two recesses in which the two pressing members are received. The two balls are located in two elongate holes of the base. When the nose assembly is moved toward the grip, the balls are pressed between the pressing members and a strike rod in the nose so that the strike rod is co-moved with the nose assembly. The piston of the strike rod is moved to a ready-to-shoot position in the cylinder. The nail gun is able to shoot nails continuously.
US11338419B1	Faucet cartridge removal tool and method of operation A faucet cartridge removal tool includes a cylindrical sleeve having an interior diameter configured such that a pipe holding a faucet cartridge fits within the cylindrical sleeve, a length configured such that a distal end of the cylindrical sleeve contacts a base of the pipe holding the faucet cartridge; a tubular extractor rod that extends through the cylindrical sleeve, the rod having a threaded exterior surface configured to thread through the threaded orifice of the cylindrical sleeve, a threaded interior surface of the rod, and a notch at a distal end, the notch configured to accept a faucet cartridge; a locking bolt that extends through the extractor rod, the bolt having a threaded exterior surface configured to thread through the threaded interior surface of the rod, wherein the threaded exterior surface at a distal end of the rod is configured to thread through a threaded orifice in the faucet cartridge.
US11338417B2	Torque wrench capable of maintaining accuracy of torque value The invention provides a torque wrench capable of maintaining accuracy of torque value, comprising a tube; and a rod, a trip mechanism, an elastic element, and an adjustment mechanism installed on the tube. The adjustment mechanism has a handle and a moving member, when the handle is rotated, the moving member can be driven to displace along a longitudinal direction of the tube, so as to change an elastic force exerted by the elastic element to the trip mechanism; an adjustment rod is threadedly connected into the moving member, rotating the adjustment rod is capable of displacing the adjustment rod relative to the moving member, so that a front end of the adjustment rod protrudes from the moving member and exerts pressure on the elastic element. Thereby, the torque wrench can be restored to a correct torque value by simply rotating the adjustment rod.
US11338416B2	Electronic torque wrench with double display screens An electronic torque wrench with double display screens includes a main body having a shank. A front end of the shank has a working head. The shank is defined with a central vertical face in the longitudinal direction. The electronic torque wrench further includes a display unit having two display screens. The two display screens are respectively disposed on two sides of the central vertical face. The two display screens are disposed by an inclination and directed upward and outward, whereby a user can easily observe the torque value displayed on the display screens.
US11338410B1	Dust removal assembly for use with disc grinder A dust removal assembly for use with a disc grinder includes a base portion with a member defining a major surface, a wall extending at least partially along an outer periphery of the major surface, an exhaust port contained within the wall, and a first ledge positioned proximate the exhaust port extending along the major surface. A top plate, attachable to the wall, includes a second ledge extending downward from a lateral edge toward the base portion such that the first ledge and the second ledge are positioned proximate to, and extend horizontally parallel to, one another. Both the first ledge and the second ledge are configured to permit a circular disc to travel therebetween. A compartment in fluid communication with an exhaust port is defined by the first ledge, the wall and a minor surface positioned below the major surface.
US11338409B2	Three-zone carrier head and flexible membrane A flexible membrane for a carrier head of a chemical mechanical polisher includes a main portion, an annular outer portion, and three annular flaps. The main portion has a substrate mounting surface with a radius R. The annular outer portion extends upwardly from an outer edge of the main portion and has a lower edge connected to the main portion and an upper edge. The three annular flaps include a first annular flap joined to an inner surface of the main portion at a radial position between 75% and 95% of R, a second inwardly-extending annular flap joined to the annular outer portion at a position between the lower edge and the upper edge, and a third inwardly-extending annular flap joined to the upper edge of the annular outer portion.
US11338408B2	Positioning device for applying an object to a grinder at pre-determined angles One embodiment of a device for positioning an object to be ground independent of the grinding tool having an armature shaft for holding an object, mounted by means of an armature and armature collar and attached to a mast, which is attached to a base. The armature shaft is used to position the object to be ground at a face angle determined by the combination of the vertical positioner length of the armature relative to the surface of the independent grinding tool. The rotational angle of the object to the grinding tool is set and can be repeated as needed by the indexed angle selector and the keyed receiver.
US11338407B2	Error measurement method for machine tool and machine tool An error measurement method for a machine tool measures an error in a machine tool that includes two or more translational axes, a table, and a spindle head. The error measurement method includes installing a masterwork having a plurality of targets on the table and detecting a position of each of the targets using a sensor mounted to the spindle head to acquire a measured value regarding the position of each of the targets and to acquire an error value regarding the position of each of the targets using each of the acquired measured values and a preliminarily acquired calibration value regarding the position of each of the targets. The error measurement method further includes calculating at least one disturbance index value indicative of a degree of disturbance in the measurement for each of the targets, and determining whether the disturbance index value exceeds a preliminarily set threshold.
US11338406B2	Estimating device and estimating system An estimating device estimating a rotary axis position of a workpiece includes first and second position acquisition units acquiring tool positions in first and second directions, a load acquisition unit acquiring first and second directional loads of the tool in the first and second directions, a determination unit determining whether or not the first and second directional loads each are a threshold or less, a turning control unit performing a lathe turning on the workpiece until the first directional load becomes the threshold or less and thereafter performing a lathe turning thereon until the second directional load becomes the threshold or less, and an estimating unit estimating the rotary axis position based on a first directional position of the tool when the first directional load has become the threshold or less, and a second directional position thereof when the second directional load has become the threshold or less.
US11338405B2	Eco-indicator for power tool A power tool includes a battery pack, one or more sensors, an indicator, and an electronic processor coupled to the battery pack, the one or more sensors, and the indicator. The electronic processor is configured to: detect, using the one or more sensors, one or more parameters of the power tool; determine a system performance based on the one or more parameters; determine a system performance level based on the system performance; and provide, using the indicator, an indication corresponding to the system performance.
US11338403B2	Chip-scattering prevention cover A chip scattering prevention cover (1) is attached to a head portion (6b) of a rotary cutter (6). The cover (1) includes an annular portion (1a) configured to be detachably fitted over an outer peripheral edge of the head portion (6b), and a plate portion (1b) extending inwardly of the annular portion (1a) from an inner circumference portion of the annular portion (1a). The plate portion (1b) is configured to cover a region of a cutout gap (6e) of the rotary cutter (6) corresponding to the head portion (6b) with the annular portion (1a) being fitted over the head portion (6b). The annular portion (1a) and the plate portion (1b) are flush with a surface of the head portion (6b) when the annular portion (1a) is fitted over the head portion (6b).
US11338394B2	Laser processing apparatus, laser processing method and thin plate processed using the same A laser processing apparatus and a laser processing method for improving the processing speed and forming uniform and highly accurate through holes when processing for forming fine through holes in a matrix in a long thin plate, and a thin plate having through holes in a matrix formed by such laser processing. A laser processing apparatus includes a cylindrical body having an opening on a circumferential surface around which a thin plate to be processed is wound obliquely, a thin plate transfer for transferring a thin plate wound around the cylindrical body in the longitudinal direction of the thin plate, a motor having a rotation axis arranged coaxially with a central axis of the cylindrical body, a reflecting member fixed to a rotating shaft of the motor, a laser light emitting means for emitting pulsed light. The apparatus continuously opens through holes in the thin plate.
US11338389B2	Battery case sealing method and a sealed battery manufacturing method In a battery case sealing method, a lid is fitted to an opening of a battery case, and then a side wall on an inner side of the battery case and a side surface of the lid are brought into contact with each other. The side wall forms the opening. In a state where the side wall on the inner side of the battery case is in contact with the side surface of the lid, a boundary portion between the side wall and the side surface of the lid is welded by irradiating a laser beam in a direction from an outer side of the battery case toward the inner side of the battery case in a thickness direction of the lid.
US11338384B2	Numerical control plasma special-shaped cutting machine tool The present disclosure discloses a numerically-controlled plasma special-shaped cutting machine tool including a bracket, a cross beam, a feeding mechanism, a clamping mechanism, a gun head moving mechanism, a material conveying system, a material receiving device, a dedusting system, an electrical control system, and an outer cover. The present disclosure adopts plasma cutting, and the surface quality is obviously improved. Material conveying and cutting are performed by a predetermined program programmed in advance, and the dimensional precision of the machining is well ensured. Workers only need to place a workpiece material on the material conveying system, and the machine tool can perform automatic cutting. The labor intensity of the workers is greatly reduced, the cutting is continuously performed, and the machining efficiency is remarkably improved.
US11338383B2	TIG welding torch body, TIG welding torch handle, and TIG welding torch having such a TIG welding torch body and TIG welding torch handle A tungsten inert gas welding torch body, a TIG welding torch handle, and a TIG welding torch has a gas channel terminating in front of the distal end of a plug-in element in an inlet opening arranged on the shell side of the plug-in element, and a central inlet mouth at the distal end of the plug-in element terminating in front of the distal end of the plug-in element in a return opening on the shell side at the plug-in element. The TIG welding torch handle has a second channel arranged coaxially to the central channel, and a third channel arranged coaxially to the second channel. A connection is between the second channel and the third channel. The first channel has a mouth in the center of the receiving part, and each of the second and third channels has a mouth on the shell side of the receiving part.
US11338382B2	Welding equipment security The subject innovation described herein generally pertains to a system and method for security features for a device in which functionality of the device can be limited or restricted in accordance with one or more security layers. To access functionality of the device, an appropriate security-related input is required.
US11338381B2	Method and system for wire electro-discharge machining a component Methods and systems for wire-electro discharge machining of components are described. The method comprises machining a first component by moving a wire-EDM electrode along a first set of cutting paths associated with a plurality of cutting passes, the cutting paths determined based on a desired profile shape of the component, obtaining a cutting parameter of the first component post-machining, determining a first modified cutting path for a second component based on the cutting parameter, and machining the second component by moving the wire-EDM electrode along a second set of cutting paths associated with the plurality of cutting passes, the second set of cutting paths comprising the first modified cutting path.
US11338376B2	Tool head and tool system including a tool head A tool head is for machining edges of a workpiece and includes a first tool section with first blades and a second tool section with second blades. The second blades are positioned between the first blades when seen in the circumferential direction. The second section is movable relative to the first section in the direction of the longitudinal axis between a passive and active position. The second blades are axially recessed relative to the first blades in the passive position and project axially outwards between the first blades in the active position. The tool head has a pressure switching mechanism for moving the second tool section between the passive and active position. In a tool system, the tool head and an actuation element can be moved axially relative to each other. The at least one actuation surface and the actuation element are configured to be axially pressed towards each other.
US11338374B2	Method for manufacturing a thin-walled part A method for manufacturing a thin-walled part having curved surfaces, in particular a turbine blade by a machine tool comprising roughing process and semi-finishing process. At least one of the roughing process and the semi-finishing process is accomplished by flank milling.
US11338373B2	Insert and body An insert is provided, ensuring to vary the cutout angle of the cutting edge without replacing the body, and to prevent the change in the cutout angle of the cutting edge in the cutting process. The insert includes a constraining part, a through hole, and a blade. The blade includes a cutting edge for the cutting process. An outer surface of the constraining part around the central axis includes a pair of first constraining surfaces, and a pair of second constraining surfaces. The cutting edge in the state where the pair of first constraining surfaces are fixed becomes non-parallel to the cutting edge in the state where the constraining part is rotated around the central axis from the fixed state of the pair of first constraining surfaces to place the pair of second constraining surfaces on the same surface on which the pair of first constraining surfaces have been fixed.
US11338368B2	Sealing ring A sealing ring for sealing an annular gap between a shaft and a bearing body surrounding the shaft, includes two sealing ring halves having ring segment shapes and a plurality of circumferentially formed sealing tips, arranged axially adjacent on the inner peripheral surface and protruding radially inward. The sealing tips are integrally formed together with the sealing ring halves. A method produces such a sealing ring.
US11338367B2	Metal powder compactors A system for compacting layers of metal powder, including: a layer of metal powder at a first voltage; and a conductive object above the layer of metal powder, the conductive object at a second voltage, wherein a voltage differential between the layer of metal powder and the conductive object is sufficient to attract particles from the layer of metal powder to the conductive object, change the voltage on the particles, and redeposit the particles in the layer of metal powder.
US11338362B2	Melting apparatus for the production of steel A melting apparatus for steel production includes a support structure to support a shell for the production and tapping of steel, and a source or zone for the emission of fumes resulting from the tapping of the steel from the shell. The melting apparatus also includes a tapping hood integrated into the support structure and provided with a suction mouth positioned directly above the zone for the emission of fumes, the shell is provided with a bottom wall in which an E.B.T. is provided for tapping the steel.
US11338361B2	Casting shell mold chamber, foundry furnace and method for casting single crystal, fine crystal and non-crystal The present disclosure discloses a shell mold chamber, a foundry furnace and a method for casting single crystal, fine crystal and non-crystal, which employ the technique of asynchronous-curving supercooling, and belongs to the technical field of precise casting apparatuses. Such a three-function foundry furnace includes a heating coil winding, a first thermal-shield assembly, a first superconducting coil, a second thermal-shield assembly and a second superconducting coil; and the first superconducting coil is provided at an inside of the first thermal-shield assembly, and the second superconducting coil is provided at an inside of the second thermal-shield assembly; and directions of a magnetic field generated by the first superconducting coil and a magnetic field generated by the second superconducting coil are opposite; and the first superconducting coil and the heating coil winding form a forward-directional static-magnetic-field heating zone, and the second superconducting coil forms a reverse-directional static-magnetic-field zone.
US11338358B2	Diecasting tool system A diecasting tool system has a machine-related base plate, at least one set of contour-imparting mould components which in an assembled position on the base plate form a casting contour for an associated cast part to be cast, and a plurality of not contour-imparting tool receptacle module components. The base plate, the tool receptacle module components and the contour-imparting mould components are configured for releasably assembling the associated set of contour-imparting mould components and an assigned set of the tool receptacle module components on a fastening side of the base plate for casting the respective cast part. The base plate on the fastening side has a fastening grid of a plurality of fastening points which are disposed so as to be distributed in a regular or irregular pattern across a fastening region. The set of contour-imparting mould components conjointly with the assigned set of the tool receptacle module components is able to be assembled on the base plate in at least two different orientations, and/or a plurality of sets of contour-imparting mould components with a respectively assigned set of the tool receptacle module components are present for selective assembling on the base plate.
US11338357B2	Diffusion article A diffusion component for impregnating molten steel with a gas includes a barrier having a first side and a second side, a through-hole formed within the barrier, the through-hole connecting the first side to the second side, and a porous element arranged within the through-hole such that the flow of molten steel passes over the porous element. At least one flow disrupter is arranged relative to the porous element and configured to promote non-laminar flow of molten steel passing through the through-hole.
US11338355B2	Method for checking a rivet The disclosure relates to a method for checking a rivet, the rivet being transported from a rivet filling station along a transporting path in the direction of a riveting machine during operation of the riveting machine. The method is characterized in that the rivet is measured on the transporting path for determining a rivet geometry of the rivet. The disclosure similarly relates to a corresponding measuring arrangement for checking a rivet.
US11338348B2	Method and apparatus for double-sided incremental flanging Flanges formed on sheet metal parts to increase the part stiffness or create mating surface for further assembly are created in an incremental sheet forming process using forming tool and supporting tool that move along a specified tool path so as to gradually deform a peripherally-clamped sheet metal work piece into the desired geometry. With two universal tools moving along the designed toolpath on the both sides of the part, the process is very flexible. Process time is can also be reduced by utilizing an accumulative double-sided incremental hole-flanging strategy, in which the flange is formed in only one step.
US11338347B2	Press device of multi cam type A multi-directional multi-cam press device may include a cam base fixed to the lower mold, a first cam slide provided to slide forwards and backwards along a first direction of the cam base, at least a first punch unit provided in the first cam slide along a first direction, a cam drive fixed to an upper mold configured of moving in a vertical direction with respect to the lower mold, and making cam contact with the first cam slide, a second cam slide provided in the cam drive to move forwards and backwards in a second direction perpendicular to the first direction and in contact with the cam base side, and at least a second punch unit provided on the second cam slide along a second direction.
US11338344B1	Tool and shell using induction heating A component forming tool for forming a component from a blank includes a die forming shell for forming the component from the blank. A first shell portion of the die forming shell is located on a first set of support elements and a second shell portion is located on a second set of support elements. The tool includes at least one induction heating coil for induction heating of a workpiece disposed within a cavity formed by the first and second shell portions. The first set of support elements include multi-material support elements having at least two layers of different materials and the second set of support elements include multi-material support elements having at least two layers of different materials.
US11338340B2	Spray header for spraying a lubricating and/or refrigerating fluid Disclosed is a spray ramp intended to lubricate and/or cool a laminated strip and/or pressure cylinders of a mill, including: a tubular shaft of which the hollow interior volume forms a fluid admission chamber; a chassis rigidly connected to the external wall of the shaft, extending along the tubular shaft; a plurality of nozzles distributed over the length of the chassis and supported by the chassis, arranged such that the jets form a fluid curtain; and a pipe system, inside the chassis, ensuring the supply of the nozzles from the through-bores provided in the tubular wall of the hollow shaft. The pipe system includes at least one pressure levelling chamber extending over the whole active length of the chassis and through which all the fluid supplying the plurality of nozzles passes.
US11338338B2	Hazardous material repository systems and methods A drillhole plug includes a frame or housing of a corrosion-resistant material and sized to fit within a milled portion of a directional drillhole that includes a hazardous waste repository; and a material that fills at least a portion of the frame or housing. The material exhibits creep such that the material fills one or more voids between the frame or housing and a subterranean formation adjacent the milled portion of the directional drillhole.
US11338337B2	Storing hazardous material in a subterranean formation Techniques for storing hazardous material include moving a storage canister sized to enclose radioactive hazardous material through an entry of a drillhole that extends into a terranean surface and is at least proximate the terranean surface; moving the storage canister from the entry through an angled drillhole portion that is coupled to the entry and deviates from true vertical at an angle; moving the storage canister from the angled drillhole portion to a hazardous material storage drillhole portion coupled to the angled drillhole portion; moving the storage canister into the hazardous material storage drillhole portion; and forming a seal in the drillhole that isolates the hazardous material storage portion of the drillhole from the entry of the drillhole.
US11338335B1	System for cleaning agricultural bins A system for cleaning agricultural bins including a conveyer belt assembly and a water jet assembly is disclosed herein. The conveyer belt includes bin rollers configured to automatically transport bins mounted thereon. The bin rollers roll bins along the conveyer assembly to the flat surface of the second end of the first section and then the bins are transferred to the cleaner section via the grapple mechanism and the pivot point to the cleaner section arranged below the bin rollers within the first section. The water jet sprays then thoroughly clean the interior and exterior of the bins. The system for cleaning agricultural bins allows a user to clean an agricultural bin in less than one minute. Furthermore, the amount of time using a water hose is reduced thereby saving money and conserving water for a user.
US11338330B2	Systems and methods of distributed printing for use with automated robotic sorting A system of distributed printing for use with automated robotic sorting has at least one work cell including a robotic sorting station, and a plurality of locations that receive sorted items from the robotic sorting station, with each of the plurality of locations having a separate printer. Each printer is configured to print labels related to items received by the respective location, wherein the printers in the work cell are configured in a network that receives data relating to the labels to be printed in the respective locations. Also included is a method of using the system and operating the automated robotic sorting station to place items in the plurality of locations, and sending data to the work cell relating to the labels to be printed in the respective plurality of locations by the separate printers and in association with the items received by the respective plurality of locations.
US11338328B2	Method for reforming coal ash, and method for producing fly ash for concrete admixture The present invention provides a method for reforming coal ash, including classifying coal ash having 10% by mass or more of a residue on a 45 μm sieve by using a forced vortex centrifugal type classifying apparatus, under a condition that the residue on a 45 μm sieve of the coal ash after the classifying becomes in a range of 1% by mass or more and 8% by mass or less.
US11338327B2	Method and apparatuses for screening A screening machine includes wall members, screen assembly guide members, a screen assembly and a compression assembly. The screen assembly includes a frame with a plurality of side members and a screen supported by the frame. The compression assembly is attached to at least one wall member and forms the screen assembly into a concave shape.
US11338326B2	Single-mass, one-dimensional resonant driver An efficiency-enhanced resonant system is provided with a backing mass connected to a linear vibrator, a parasitic mass connected to the linear vibrator, a positioning spring, a connecting device, and external biasing springs. The linear vibrator provides vibrating force to the parasitic mass which is connected to the connecting device, grasping a working implement. The use of separate positioning spring and external biasing springs accommodates a tuned system that balances the reduction in backing mass movement, avoids backing mass resonance within the working range of frequencies, and maintains a minimized linear vibrator stroke within the optimal range for one-dimensional implements within desired frequency ranges. The linear vibrator provides vibration that manifests as a frequency range of the natural frequency of the combined assembly of the parasitic mass, positioning spring, external biasing springs, connecting device, and implement, so that the resonant system efficiently performs work with minimized wasted energy.
US11338315B2	Articulating nozzle An improved nozzle assembly includes a housing having an inlet for directing media (e.g. cleaning fluid) into the housing, and a nozzle core rotatably coupled to the housing. The nozzle core includes a sprayer shaft and a vane coupled thereto. The sprayer shaft defines a peripheral outlet, and is adapted for passage of media from the housing through the outlet. The vane is adapted to receive media from the inlet to rotationally bias the nozzle core in a first direction and radially orient the outlet to an activated position. The nozzle core is rotationally biased in a second direction opposite the first to radially orient the outlet to a home position different than the activated position. A system including the nozzle assembly, and methods of using each of the same, are also disclosed.
US11338314B2	Nozzle device and nozzle unit In order to enable the outflow direction of a fluid to be changed and to enable the outflow position of the fluid to be freely set, a nozzle device (7) of the present invention comprising: a flow path body that flows or holds a fluid and that has a flow path wall (6); and a nozzle unit (1) including a nozzle body (3) having a spherical surface on an outer periphery thereof and having a fluid passage (3a) formed thereinside, a holding mechanism of the nozzle body (3), and a securing member (4) that fixes the holding mechanism to the flow path wall (6), wherein the holding mechanism is made of a pair of thin plate members (2), each having a contact holding portion (2b) in contact with the spherical surface of the nozzle body (3) and having a flat portion (2a), and the holding mechanism rotatably holds the spherical surface in a state in which the nozzle body (3) is sandwiched by the contact holding portions (2b) of a pair of the thin plate members (2).
US11338310B1	Manually operated dispensing pump A manually operated pump including: an inlet one-way valve; a pump chamber downstream of and in fluid communication with the inlet one-way valve; a piston interior to the pump chamber and slideably engaged with the pump chamber; an actuator engaged with the piston or the pump chamber; a block thermoplastic elastomeric spring engaged with the actuator to move the actuator as the block thermoplastic elastomeric spring relaxes; and an optional outlet one-way valve downstream of and in fluid communication with the pump chamber.
US11338309B2	Connection system between a bottle and a dispensing head A connection system between a head and a bottle of a trigger dispensing device includes a main skirt having a first flexible tab and a neck having a first sloping plane and a first pocket. The first flexible tab extends circumferentially from a first end to a second end, and the first end is joined to an annular wall by a closing wall. The system also provides for an auxiliary window obtained through the annular wall of the main skirt, and a rigid auxiliary tooth of the neck, suitable to snap into the auxiliary window.
US11338307B2	Spray-head assembly and spray-head apparatus A spray-head assembly includes a pipe structure and a valve-spool. The pipe structure includes a liquid inlet, a flow pathway, and a valve-port. The flow pathway includes an air-flow pathway arranged obliquely with respect to a central axis of the liquid inlet. A bottom end of the air-flow pathway communicates with the liquid inlet. The valve-port is arranged at a top end of the air-flow pathway. The valve-spool is arranged in the flow pathway and configured to control opening and closing of the valve-port.
US11338306B2	Showerhead This disclosure relates to a showerhead including a body, a stationary plate, a spring, and an insert fitting member. The body has an upper body and a lower body. The upper body and the lower body form an accommodation space. A water inlet for supplying water into the accommodation space is provided at the upper body, and a plurality of water outlets for spraying water from the showerhead are provided on the lower body. The stationary plate is located in the accommodation space and movable up and down in the accommodation space along a direction of the water flow. The spring is disposed between the stationary plate and the lower body, for applying a force to the stationary plate away from the lower body. The insert fitting member is fitted to the stationary plate. The position of the insert fitting member corresponds to the plurality of water outlets on the lower body. When the water is supplied, the stationary plate moves to a lower position under the action of water pressure, and the insert fitting member partially closes the water outlet to form a drizzle-type spray; and when the water is turned off, the spring pushes the stationary plate back to the upper position, and the water outlet plug leaves the water outlet.
US11338302B1	Apparatus and test method for simulating spark discharge of high-voltage electrostatic precipitator An apparatus and test method for simulating spark discharge of a high-voltage electrostatic precipitator are provided. The simulation apparatus includes a pulse power supply configured to provide a test voltage, an anode cylinder configured to simulate an anode of a precipitator, a cathode rod configured to simulate a cathode of the precipitator, a pulse capacitor unit configured to simulate an electrode capacitor of the precipitator, an insulating support configured to hang the cathode rod, a voltage divider configured to measure an electrode voltage, and a grounded current sampling unit configured to measure grounded current. The simulation apparatus simulates a discharge process of the high-voltage electrostatic precipitator to measure discharge characteristic parameters such as discharge current and discharge energy of the high-voltage electrostatic precipitator. In this way, characteristics of spark discharge of the precipitator under different load conditions are simulated.
US11338299B2	Pin mill A pin mill includes a rotor plate mounted on a shaft and having concentrically spaced-apart circular arrays of pins arise from an end face. The rotor pins interdigitate with complementary concentric arrays of pins arising from a face of a stator mounted on a door. The door swings open on a hinge mounted on two translator pins so that the door can translate the interdigitated pins before swinging open so that the pins arrays do not collide with each other while the door is opening. The rotor operates within a cylindrical screen which retains particles being broken up until they are small enough to exit. The rotor also includes a circular array of vane knives which sweep closely within the screen and also entrain cooling air into the macerating volume of the mill. Oversized particles trapped in the screen also get cleared and split apart by the passing vane knives.
US11338298B2	Material reducing apparatus having a system for allowing a reducing rotor to be selectively configured in multiple different reducing configurations The present disclosure relates to a system for a material reducing machine that allows a reducing rotor to be selectively configurable in a plurality of different reducing configurations. The different reducing configurations in which the reducing rotor can be configured can include reducing configurations having reducers located at different positions, reducing configurations having different reducer densities (e.g., different overall densities and different regionalized densities), reducer configurations having different reducer counts, reducer configurations having different reducer patterns, and reducer configurations having different lay-outs.
US11338297B2	Sample rack, sample access kit and sample access system This disclosure provides a sample rack, a sample access kit and a sample access system. The sample rack comprises: a rack body for placing a sample container; a position collector configured to acquire a position of the sample container placed on the rack body; and a communicator configured to transmit identification information of the sample rack and the acquired position of the sample container on the rack body. The sample access kit comprises the above-described sample rack and a sample container having an identification disposed thereon. The sample access system comprises the above-described sample access kit and a mobile terminal.
US11338293B2	Microfluidic device, droplet identification method and droplet control method A microfluidic device includes a first substrate and a second substrate opposite to each other. A light-emitting layer, a first driving layer, and a first hydrophobic layer are on surface of the first substrate facing the second substrate; and first hydrophobic layer is disposed near second substrate; a photosensitive layer, a second driving layer and a second hydrophobic layer are on surface of the second substrate facing the first substrate; and second hydrophobic layer is disposed near first hydrophobic layer, and a gap for holding a droplet is between second hydrophobic layer and first hydrophobic layer; the first and second driving layers are configured to drive the droplet to move within the gap when applied with a driving voltage; the light-emitting layer is configured to emit light with a set wavelength toward the gap; and the photosensitive layer is configured to generate an induced current according to received light.
US11338292B2	Microfluidic particle sorting apparatus and manufacturing method thereof A microfluidic particle sorting apparatus for capturing targets from fluid containing the targets is disclosed. The apparatus includes an inlet for receiving the fluid; a sorting chamber allowing the fluid to flow through; a first outlet for discharging the fluid after flowing through the sorting chamber; a capturing structure for capturing the cells, wherein the capturing structure is upstream of the first outlet, and includes obstacles in an array, each extending through the sorting chamber in a lateral direction with respect to a fluid flow of the fluid; and a second outlet upstream of the capturing structure comprising a plurality of openings; wherein a gap between two adjacent obstacles is equal to or greater than each opening of the second outlet.
US11338291B2	Jet flow power control for object sorting Disclosed herein are microfluidic actuators for selecting objects in a fluid stream comprising a plurality of objects. In some embodiments, the actuator comprises an object detection means adapted for, upon arrival of an object, identifying whether an object is an object of interest. It further comprises a heater adapted for generating a jet flow for deflecting an object of interest from the fluid stream and a controller for activating the heater as function of the detection of an object of interest using a nucleation signal. The controller is adapted for obtaining temperature information of the heater and for adjusting a nucleation signal for the heater taking into account the obtained temperature information. Also disclosed are microfluidic systems and diagnostic devices comprising the microfluidic actuators of the disclosure, as well as methods of use thereof.
US11338285B2	Fluidic cell designs for interfacing microfluidic chips and nanofluidic chips A technique relates to a fluidic cell configured to hold a nanofluidic chip. A first plate is configured to hold the nanofluidic chip. A second plate is configured to fit on top of the first plate, such that the nanofluidic chip is held in place. The second plate has at least one first port and at least one second port. The second plate has an entrance hole configured to communicate with an inlet hole of the nanofluidic chip. The second port is angled above the first port, such that the first port and second port intersect to form a junction. The second port is formed to have a line-of-sight to the entrance hole, such that the second port is configured to receive input for extracting air trapped at a vicinity of the entrance hole.
US11338283B2	Kit for centrifugal separation of biological fluid components and a method for centrifugal separation of biological fluid components A kit for centrifugal isolation of a fraction of interest from a multi-component composition according to density, comprising: a separation chamber (200) having an inlet (210) for introducing the multi-component composition and a base through-hole (220); characterized in that the separation chamber (200) comprises: an inlet section (211) communicating with the inlet (210), a base section (212) communicating with the base through-hole (220), wherein the inlet section (211) and the base section (212) communicate with each other via a necked duct (230) for detaching the inlet section (211) and the base section (212) at the necked duct (230), wherein the separation chamber (200) has a form of a syringe in which the inlet of the separation chamber (200) is connectable with an extension nozzle or needle (215) for drawing the multi-component composition, and wherein the kit further comprises a plunger (240) for embedding and being slidably moved within the base section (212) of the separation chamber (200), wherein the plunger (240) comprises a plunger handle (242), removably attached to a plunger base (241), for sealing the base through-hole (220), and wherein the diameter of the necked duct (230) lumen is selected so as to maintain the multi-component composition, after detaching the inlet section (211) and the base section (212) at the necked duct (230), in the inlet section (211), by virtue of a partial negative pressure created within the inlet section (211) when the inlet (210) is sealed.
US11338281B2	Pipetting device and method for producing same The invention further relates to a method for producing said pipetting device. The invention relates to a pipetting device, in particular for pipetting a fluid sample by suctioning into a pipetting container using air under a pipetting pressure, having the following: —a valve assembly with at least one valve device for adjusting a pipetting pressure, said valve device having a valve chamber; —at least one pump device which is connected to the valve chamber in order to generate a chamber pressure in the valve chamber; —a pipetting channel which is connected to the pipetting container, and—a bypass channel which is open towards the surroundings, wherein—the pipetting channel and the bypass channel are each connected to the valve chamber; and—the at least one valve device has a closure element with a closure surface which is designed such that the chamber pressure is distributed to the pipetting channel and the bypass channel in a metered manner by the valve device in order to generate the desired pipetting pressure in the pipetting channel. The invention further relates to a method for producing said pipetting device.
US11338280B2	Catalytic reactor system treatment processes There are provided methods of treating a catalyst-containing reactor system with a liquid solvent to remove contaminants from the reactor system. An exemplary method includes the steps of: isolating the reactor system to be treated from upstream and downstream equipment; reducing the temperature and pressure of the isolated reactor system by flushing with a hydrogen rich gas; injecting a non-aqueous liquid solvent into the reactor system at an injection point while continuously flowing hydrogen-rich gas through the reactor system; maintaining the solvent in a liquid state while flowing the solvent continuously through the reactor system; and terminating the step of injecting solvent and terminating the continuous flowing of hydrogen-rich gas. The exemplary method is free of the injecting of a carrier gas into the reactor system comprising alkanes selected from the methane, ethane, propane, butane and pentane.
US11338279B2	Method for preparing a selective bimetallic hydrogenation catalyst made of nickel and copper A method for preparing a catalyst with a bimetallic active phase made of nickel and copper, and a support comprising a refractory oxide, wherein the method involves: a) placing the support in contact with at least one solution containing a nickel precursor; b) placing the support in contact with a solution containing a copper precursor; wherein a) and b) are carried out separately in any order; c) drying the catalyst precursor at the end of a) and b), or b) and a), at a temperature less than 250° C.; and d) supplying the catalyst precursor obtained at the end of c), into a hydrogenation reactor, and carrying out a reduction step by placing the precursor in contact with a reducing gas at a temperature of less than 200° C. and for a period greater than or equal to 5 minutes and less than 2 hours.
US11338276B2	Catalyst for preparing chloroethylene by cracking 1,2-dichloroethane and a preparation and regeneration method thereof A catalyst for preparing chloroethylene by cracking 1,2-dichloroethane and a preparation and regeneration method thereof are disclosed in the present application. A catalyst for preparing chloroethylene by cracking 1,2-dichloroethane includes a carrier and a nitrogen-containing carbon as an active component of the catalyst with the nitrogen-containing carbon being loaded on the carrier. The method for preparing the catalyst includes: supporting an organic matter on an inorganic porous carrier and then performing a carbonization-nitridation process by pyrolysis in an atmosphere containing the nitrogen-containing compound. The method for regenerating the catalyst includes: calcinating the catalyst with deactivated carbon deposit in an oxidizing atmosphere to remove all the carbonaceous portions on the surface, and repeating the above preparation process of the catalyst. The catalyst reduces reaction temperature, reduces energy consumption, reduces production cost, and improves selectivity and conversion rate and is inexpensive and reproducible, and has a long service life.
US11338274B2	Oxidative dehydrogenation catalysts Provided in this disclosure are oxidative dehydrogenation catalysts that include a mixed metal oxide having the empirical formula: Mo1.0V0.12-0.49Te0.05-0.17Nb0.10-0.20Od wherein d is a number to satisfy the valence of the oxide. The oxidative dehydrogenation catalyst is characterized by having XRD diffraction peaks (2θ degrees) at 22±0.2, 27±0.2, 28.0±0.2, and 28.3±0.1. The disclosure also provides methods of making the catalysts that include wet ball milling.
US11338269B2	Catalytic hydrocarbon dehydrogenation A catalyst for dehydrogenation of hydrocarbons includes a support including zirconium oxide and alumina. A concentration of the zirconium oxide in the catalyst is in a range of from 1 weight percent (wt. %) to 20 wt. %. The catalyst includes from 0.01 wt. % to 2 wt. % of an alkali metal or alkaline earth metal. The catalyst includes from 1 wt. % to 2 wt. % of tin. The catalyst includes from 0.1 wt. % to 2 wt. % of a platinum group metal. The alkali metal or alkaline earth metal, tin, and platinum group metal are disposed on the support.
US11338265B2	Method for preparing microcapsules and microparticles of controlled size The present invention relates to a method for the preparation of microparticles and solid microcapsules comprising the following steps: a) the addition, with stirring, of composition C′2 in a composition C3, the compositions C′2 and C3 not being miscible with each other, the composition C′2 being either a monophasic composition C2 or an emulsion (E1) comprising drops of a composition C1, comprising at least one active ingredient, dispersed in a polymeric composition C2, the compositions C1 and C2 not being miscible in each other, the viscosity of composition C3 being greater than 10,000 mPa·s at 25° C. at a shear rate of s−1 and being less than 10,000 mPa·s at 25° C. at a shear rate of between 100 s−1 and 100,000 s−1, wherein an emulsion (E2) is obtained b) applying shear to the emulsion (E2), the applied shear rate being less than 1000 s−1, wherein an emulsion (E3) is obtained; and c) the polymerization of the composition C′2.
US11338264B2	Fluidized bed cooler with regional coordination enhancement The present disclosure discloses a fluidized bed cooler with regional coordination enhancement, comprising a shell, a catalyst inlet, an interior of the shell is divided into a catalyst inlet influence region, a dilute phase region, a dense phase region and a gas distributor influence region; a catalyst inlet inclined tube is provided obliquely upward at the catalyst inlet, and a regional particle distributor is provided at the catalyst inlet; the dense phase region is provided with a plurality of dense phase baffle plates, and the dilute phase region is provided with a plurality of dilute phase baffle plates; and the gas distributor influence region is provided with double gas distributors. The fluidized bed cooler simultaneously well solves the low internal stability and the low heat exchange efficiency of the fluidized bed cooler, thereby realizing the stable and efficient operation of the fluidized bed cooler.
US11338263B2	Continuous slurry-bed tank reactor and method of using same A continuous slurry-bed tank reactor, comprising a tank reactor body, an agitator, and tubular separation membranes. A method of using the continuous slurry-bed tank reactor comprising adding a catalyst, feeding reactants, stopping feeding the reactants, starting a heating system, changing directions of the reactants flowing through the tubular separation membranes.
US11338260B2	Vacuum particulate recovery systems for bulk material containers Systems and methods for recovering dry bulk material from a blender at a job site are provided. The systems include at least one container having in which dry bulk material can be placed and a skid-mounted vacuum unit comprising a tank having an interior space and an outlet for interfacing with the inlet of the container when the vacuum unit is positioned proximate to the container, a vacuum pump in communication with the interior space of the tank, and a conduit coupled to an inlet of the vacuum pump for interfacing with an inlet of a blender.
US11338258B2	Rotary-pulsation device Devices for treating aqueous pulps of organic materials usable in the food industry, perfumes, in the production of technical and food alcohol, in the processing of organic waste, etc., are provided. A rotary-pulsation device contains a drive, a stator, and a rotor installed in a housing. A vibration sensor is installed on an outer side of the stator to diagnose conditions of the working bodies and for continuous correction the shaft rotation speed. Reliability of the rotary-pulsation device and processing efficiency are increased by reducing manual cleaning related stops and breakage-related failures. The scope of usage is expanded because automatic processing of water pulps containing large-sized and extended fragments becomes possible; the treated pulp is saturated with small gas bubbles; and automation capabilities may be expanded when integrating the device into substrate processing systems.
US11338248B2	Porous membrane The object of the present invention is to provide a porous membrane by which a useful component can be recovered while suppressing the clogging during filtration of a protein solution and from which only a small amount of an eluate is eluted even when an aqueous solution is filtered.The present invention provides a porous membrane containing a hydrophobic polymer and a water-insoluble hydrophilic polymer, the porous membrane having a dense layer in the downstream portion of filtration in the membrane, having a gradient asymmetric structure in which the average pore diameter of fine pores increases from the downstream portion of filtration toward the upstream portion of filtration, and having a gradient index of the average pore diameter from the dense layer to the coarse layer of 0.5 to 12.0.
US11338240B2	Particulate matter collecting apparatus A particulate matter collecting apparatus includes a duct, a water sprayer, a micro-channel forming unit, and an impactor. A gas-liquid mixed fluid is formed by spraying water to air flowing along the inside of the duct using the water sprayer. The gas-liquid mixed fluid collides with a collision plate of the impactor after passing through a plurality of micro-channels provided in the micro-channel forming unit. Particulate matter in air is collected by droplets or a liquid film formed on the plurality of micro-channels and the collision plate. Water flowing down from the plurality of micro-channels is discharged through a first water outlet.
US11338235B2	Filter device comprising a filter element in a filter housing A filter device is provided with a filter housing provided with a housing wall and with a filter element arranged in the filter housing. The filter element has an annular filter medium body and an end disk arranged at an end face of the filter medium body. The filter medium body surrounds in a ring shape an inwardly positioned flow space for receiving a fluid to be filtered. An annular circumferentially extending flow path is positioned between an outer contour of the end disk and an inner side of the housing wall of the filter housing. Guide vanes project into the annular circumferentially extending flow path. The guide vanes are fastened at the end disk at the filter element. A cover is arranged at the end disk at the filter element and covers a portion of the annular circumferentially extending flow path.
US11338233B2	Air filter medium, filter pleat pack, and air filter unit The air filter medium of the present invention is an air filter medium including a stack of a porous polytetrafluoroethylene (PTFE) membrane and an air-permeable support member, a repulsive force generated in the medium when the medium is compressed in a thickness direction thereof is equal to or greater than 30 kPa and equal to or less than 150 kPa at a compression ratio of 30%, and at least one main surface of the air filter medium is formed by the air-permeable support member and has a maximum coefficient of friction of 24 gf or less. The air filter medium of the present invention is an air filter medium that uses a porous PTFE membrane and in which a decrease in collection efficiency due to pleating is inhibited.
US11338231B2	Oil management structures in crankcase ventilation A gas-liquid separator includes a housing. The housing includes an inlet structured to receive a blowby gas stream from a crankcase. a cleaned air outlet, and a liquid outlet. A cover is disposed downstream from the inlet and upstream from the liquid outlet. The cover includes a baffle disposed over the blowby gas stream flow path from the inlet. The blowby gas stream impacts the baffle and separates liquid and aerosol contained in the blowby gas stream. A flange extends substantially axially downward from a side of the baffle. The flange is tapered substantially axially downward forming an inner surface. The inner surface is structured to route the separated liquid toward the liquid outlet. The inner surface biases separated liquid away from shedding toward the cleaned air outlet.
US11338225B2	Filter agitator Embodiments of the present disclosure describe filter agitators, filtration units comprising the filter agitators, methods of using the filter agitators, and the like. In certain embodiments, the filter agitators comprise a plurality of first fins extending outwardly from a central vertical axis and arranged in a plane oriented substantially perpendicular to the central vertical axis, wherein the plurality of first fins is configured to promote laminar flow of a fluid flowing in a first direction and induce turbulent flow of a fluid flowing in a second direction; and optionally a plurality of second fins positioned above the plurality of first fins and extending outwardly from the central vertical axis, wherein the plurality of second fins is configured to induce or further induce turbulent flow.
US11338219B2	Dividing wall debutanizer column, system and method of operation Embodiments disclosed relate to a debutanizer with a dividing wall. The configuration of the debutanizer includes having a feed section, a top section, a bottom section, and a draw-off section. The debutanizer produces a C4s product, a C5s product and a natural gasoline (NG) product from a C4+s feed. The dividing wall is configured such that an upper portion of the dividing wall is positioned off-set from a vertical centerline and a lower portion of the dividing wall is positioned along the vertical centerline of the debutanizer. A process of use of the debutanizer is also disclosed. A natural gas liquids (NGL) system that includes parallel debutanizers, each with a dividing wall, and a process of use of such system, is also disclosed.
US11338214B2	Dark ride tower systems having stationary and adaptable rooms A dark ride tower system includes a tower having first and second levels. The first level includes a stationary room having stationary walls and the second level includes an adaptable room having adaptable walls configured to be rearranged into a plurality of physical configurations. The dark ride tower system also includes a lift system configured to alternatingly move a ride vehicle between the first and second levels. In addition, the dark ride tower system includes a first projection system configured to generate projection mapping on the stationary walls to simulate movement of the ride vehicle relative to the stationary room while the ride vehicle is disposed within the stationary room. The dark ride tower system also includes a second projection system configured to generate projection mapping on the adaptable walls to present a show scene while the ride vehicle is disposed within the adaptable room.
US11338211B2	Information processing apparatus and game image distributing method An application execution unit 110 generates a game image. A message generation unit 112 generates a notification message. An image processing unit 118 generates a distribution image including the game image. A distribution processing unit 126 distributes the distribution image to one or more information processing terminals through a shared server. A setting unit 114 allows a user to set whether or not the notification message is included in the distribution image so as to be visually recognizable, and registers setting contents in a storage apparatus.
US11338209B2	Methods, systems, apparatuses, and devices for facilitating conducting a competition between participants Disclosed herein is a method of facilitating conducting a competition between participants, in accordance with some embodiments. Accordingly, the method comprises receiving a registration request from a participant device, registering a participant, identifying first participants, transmitting a participant list to the participant device, receiving a selection of a first participant from the participant device, generating a challenge notification, transmitting the challenge notification to a first participant device, receiving participant content from the participant device, receiving first participant content from each first participant device, analyzing the participant content and the first participant content, selecting a participant content and a first participant, transmitting the participant content and the first participant content to a viewer device, receiving a score for each of the participant and the first participant from the viewer device, analyzing the score, determining a winner of the competition, generating a reward for the winner, and storing the reward.
US11338206B2	Information processing system, information processing apparatus, computer-readable non-transitory storage medium having information processing program stored therein, and information processing method A plurality of content groups are stored in a memory, and some of the content groups are determined as selectable target groups by a selection. One content group is selected from among the selectable target groups on the basis of a user's operation, and a selection process is executed for the one content group. A content selected is given to the user, and a given status of each content is stored in the memory such that this given content is excluded. In addition, when a predetermined condition is satisfied, selectable target groups are selected again. At this time, the given status of each content in each content group is retained regardless of which content groups are set as the selectable target groups.
US11338202B1	Methods and systems for dynamic quest diversification Methods and systems are provided for executing a video game for a player. The method includes determining a golden path associated with a gameplay of a player. The golden path includes a plurality of main story quests associated with the golden path. The method includes processing the gameplay to identify player gaming metrics as the player progresses along the golden path. The player gaming metrics includes a profile for a plurality of inputs received for a game region associated with one of the plurality of main story quests. The method includes generating an engagement score of the player based on the profile of the plurality of inputs and the game region. The method includes generating a dynamic quest for the player. The dynamic quest is generated responsive to a determination that the engagement score has fallen below a score threshold for the game region. The dynamic quest has a quest type that is arranged to increase the engagement score of the player above the score threshold. In this way, a video game is executed for a player which can provide the player with a customized gaming experience so that the engagement of the player is maintained or enhanced.
US11338200B2	Server load prediction and advanced performance measures Methods and systems for provisioning resources for games executed by a cloud gaming system includes accessing online interactions of a plurality of users in relation to a game. The online interactions are processed to classify discussion features obtained from online social communications. A model is generated to predict game use, using the classified discussion features. The model is updated with online interactions received over time. Resources for the game are provisioned at a data center. The provisioning is done by accessing the model and identifying adjustments in the provisioning for an anticipated usage spike that is to occur by a plurality of users, based on current online interactions.
US11338188B2	Braking mechanism for a self-powered treadmill A mechanical braking system which can provide a brake to a self-powered treadmill, or a dual mode treadmill that can operate in both self-powered and motor-powered modes, that will rapidly halt the motion of the belt or rollers in the event of a power disconnect such as from the removal of a safety key.
US11338187B2	Golf club for practicing swings The present invention relates to a golf club for practicing swings which enables learning a smooth rhythmic sensation under the concept of hitting a ball with a sphere having a metal texture, so as to maintain a stable swing track involving proper rhythm in real swings to correctly send a ball to a desired position. The golf club for practicing swings comprises: a shaft provided with a handle at the top end; and a head coupled to the bottom end of the shaft, wherein the sphere providing a metallic material sensation is integrally formed with the face of the head or detachably formed on the head, thereby providing an image of softly hitting a ball with the sphere made from the metallic material during practice swings.
US11338178B2	Golf ball and method of manufacture In a golf ball having a core composed of one or more layer, the outermost layer of the core is formed of a rubber composition containing a base rubber and an α,β-unsaturated metal carboxylate, an envelope layer directly encasing the core is formed of a resin composition containing a thermoplastic resin having a structure that includes α,β-ethylenically unsaturated carboxylic acid copolymerization units, and a surface of the core outermost layer and the envelope layer adjoin each other through an intervening oxazoline group-containing substance. The golf ball has improved adhesion between the rubber-based core and the cover layer that directly encases the core and is formed of an ionomer resin or other α,β-ethylenically unsaturated carboxylic acid copolymer-containing resin material.
US11338174B2	Method and system of planning fitness course parameters A method for planning parameters of a fitness course is disclosed. The method includes the following steps: generating a plurality of limb motion signals by sensing a plurality of limb motions of a body builder through a sensing module, and sensing a physiological state of the body builder to generate a physiological state signal via the sensing module; obtaining a workout characteristic index (WCI) by performing a first calculation related to the plurality of limb motion signals, and obtaining a physiological effect index (PEI) by performing a second calculation associated with the physiological state signal; obtaining a workout effect index (WEI) by performing a third calculation associated with the WCI and the PEI; and evaluating a plurality of categorical factors associated with the WEI to plan the parameters of the fitness course.
US11338168B2	Fitness exercise apparatus A fitness exercise apparatus includes a main frame, a seat frame, a plurality of elastic cords, a plurality of pulling units and a pair of handles. The main frame includes a support unit having bottom and top portions. The seat frame includes a guide rail, and a seat assembly slidably disposed on the guide rail and movable toward and away from the support unit. Each elastic cord extends from the bottom to the top portion of the support unit. Each pulling unit includes a plurality of pulley sets provided on the main frame and the seat frame, and a plurality of wires each of which is looped around a corresponding pulley set and connectable with a corresponding elastic cord. Each handle is connected to a selected one of the elastic cord and the wire.
US11338162B2	Low molecular weight polyethylene glycol (PEG) in fluorine containing fire fighting foam concentrates It has been discovered that low molecular weight poly(ethyleneglycol) (PEG) can be used in place of diethylene glycol monobutyl ether (DGME) in fire foam concentrates without compromising the desirable properties provided by DGME. Surprisingly it has been found that lower molecular weight PEG with a weight average molecular weight Mw of 400 or less provides comparable performance to DGME with considerably lower toxicity. Use of this PEG permits preparation of fire foam concentrates that exclude DGME completely and that are less toxic than conventional DGME-containing concentrates.
US11338156B2	Noninvasive tissue tightening system Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.
US11338154B2	Bacteria removal laser A bacteria removal laser is provided, especially for removing caries bacteria from natural or prosthetic teeth, the prosthetic teeth also being treated via extraoral approach, having a gripping handle, a laser radiation source, an application optics having a predetermined radiation exit surface, especially a radiation guide rod through which laser radiation passes, and an energy source such as a mains connection or an accumulator. The laser emits in the wavelength range between 2200 nm and 4000 nm and is especially designed as an Er:YAG laser. The energy output averaged over time is less than 1 mJ/mm2 at the radiation exit surface.
US11338149B2	Methods and apparatus for electrically inducing a peripheral nerve blockade Methods and devices are disclosed for inducing analgesia in a localized region of tissue. Inducing analgesia may be performed by identifying a nerve associated with the localized region, determining a resonant frequency for target neuronal cell membranes of the nerve, and generating a peripheral nerve blockade using the determined resonant frequency. The resonant frequency may be a frequency at which impedance of the nerve approaches a maximum.
US11338146B2	System for adjusting ventricular refractory periods A system is provided for controlling a left univentricular (LUV) pacing therapy using an implantable medical device (IMD). The system also includes one or more processors configured to determine an atrial-ventricular (AV) conduction interval (ARRV) between the A site and a first RV sensed event at the RV site, determine an inter-ventricular (VV) conduction interval (RLV-RRV) between a paced event at the LV site and a second RV sensed event at the RV site, and set a ventricular refractory period (VRP) based on at least one of the AV conduction interval or the VV conduction interval and a predetermined offset. The one or more processors are also configured to blank signals over the RV sensing channel during the VRP.
US11338145B2	Current steering to achieve spatial selectivity for his bundle pacing Various aspects of the present disclosure are directed toward apparatuses, systems, and methods for pacing a HIS bundle of a patient. The apparatuses, systems, and methods may include applying stimulation energy through one or more of a plurality of electrodes to direct a stimulation locus and pace a HIS bundle of a patient.
US11338143B2	Control apparatus for treating myocardial infarction and control method for treating myocardial infarction A stimulation control unit that outputs a stimulation signal for reducing a myocardial workload to an electrode for stimulation inserted in a blood vessel running in the vicinity of the vagus nerve of a patient in order to stimulate the vagus nerve; a detecting unit that detects first biological information and second biological information of the patient; a setting unit that sets threshold information for determining a normal range of the first biological information and second biological information; and a determining unit that determines whether or not values of the detected first biological information and second biological information are within the normal range determined in the threshold information; where the stimulation control unit adjusts the intensity of the stimulation signal such that the values of the first biological information and second biological information are within the normal range, and the value of the second biological information is reduced by a predetermined ratio or more as compared to a value before the stimulation.
US11338134B2	Skin treatment device using RF A skin treatment device includes: an RF generator configured to generate an RF output; and an applicator being of a bipolar type and including an applicator body and needles, wherein the needles are arranged on a front surface of the applicator body, inserted into a dermal layer of the skin of a person to be treated and electrically connected to the RF generator to transmit the RF output, wherein, when the applicator is turned on, the applicator transmits a single or a plurality of RF pulses according to the RF output to the person to be treated, and the RF output is 5 W or more and 13 W or less, and a frequency of the RF output is greater than 1 MHz and less than 3 MHz, and a duration of the RF pulse according to the RF output is 50 ms or more and 100 ms or less.
US11338133B2	Device for relieving pains and spasms comprising a device for protecting against static electricity and a device for triggering the activation of said relieving device A device for relieving pains and spasms by applying electrical pulses which makes it possible to render the electrical pulses easier to tolerate by limiting or preventing the painful or untimely discharges which hamper the use of the relief device. The relief device delivers electrical pulses only when it bears or rolls in a back-and-forth movement on the skin or clothing of a user. The relief device comprises means for limiting the maximum voltage delivered to the user, one or more means of triggering the pulses delivered by the electrodes, an activation delayer and a system for progressively launching the potential delivered by the electrodes.
US11338129B2	Selective electrical modulation of neural populations Methods of providing electrical neural modulation to a patient's brain are disclosed herein. The methods involve differentially modulating two or more target regions of the brain. For example, a first target region may be provided with an electrical neural modulation signal that activates that target region while a second target region is provided with an electrical neural modulation signal that suppresses or deactivates that target region. As the implantable pulse generators (IPGs) described herein include independent current sources, such differential modulation can be provided with a single IPG.
US11338124B2	Catheter device The catheter device comprises a drive shaft connected to a motor, and a rotor mounted on the drive shaft at the distal end section. The rotor has a frame structure which is formed by a screw-like boundary frame and rotor struts extending radially inwards from the boundary frame. The rotor struts are fastened to the drive shaft by their ends opposite the boundary frame. Between the boundary frame and the drive shaft extends an elastic covering. The frame structure is made of an elastic material such that, after forced compression, the rotor unfolds automatically.
US11338118B2	Swallowable drug delivery device and methods of drug delivery Embodiments of the invention provide swallowable devices, preparations and methods for delivering drugs and other therapeutic agents within the GI tract. Some embodiments provide a swallowable device such as a capsule for delivering drugs into the intestinal wall or other GI lumen. The device comprises a capsule sized to be swallowed and pass through the intestinal tract. The capsule can include at least one guide tube, one or more tissue penetrating members positioned in the guide tube, a delivery member, an actuating mechanism and a release element. The release element degrades upon exposure to various conditions in the intestine so as to release and actuate the actuating mechanism. Embodiments of the invention are particularly useful for the delivery of drugs which are poorly absorbed, tolerated and/or degraded within the GI tract.
US11338115B2	Finned angioplasty balloon An angioplasty balloon (1) comprises an elongate tube (16) having a relaxed delivery configuration and an expanded deployed configuration. The elongate tube (16) comprises a proximal neck portion (10), a distal neck portion (8), a main body region, a tapered proximal portion (11) extending between the main body region and the proximal neck portion (10); and a tapered distal portion (9) extending between the main body region (3) and the distal neck portion (8), the elongate tube has only three fins (4, 5, 6) which are integrally formed with the tube and which are spaced equidistant from one another about the exterior of the tube. The fins (4, 5, 6) project radially outwardly from the exterior surface of the tube and the fins (4, 5, 6) extending longitudinally only along part of the main body region (3), resulting in the end-sections of the balloon main body being fin-free.
US11338113B2	Needle position indicator A catheter system having one or more needle position indicators to assist an operator in withdrawing the introducer needle to a “parked” position, as part of a catheterization procedure, wherein the needle position indicator provides a visual indication to the operator.
US11338112B2	Devices for monitoring movement of a secured catheter during a procedure A device for securing and monitoring movement of a catheter includes a film having an adhesive disposed on a body-facing surface for securing the film to a body. The device also includes a base mounted on the film, the base comprising a first portion of a guide channel for receiving the catheter. A cover is coupled to the base via a hinge, the cover comprising a second portion of the guide channel, the cover further comprising a rounded portion extending from a distal end of the cover, wherein in the closed configuration, the catheter is completely enclosed by the rounded portion and the first and second portions of the guide channel. The device also includes a positional shift indicator fixedly attached to the catheter and configured to indicate positional shifts by the catheter within the guide channel.
US11338110B2	Flexible elongated structure having a steerable end An elongated steerable system for guiding a catheter or an endoscope, comprising: an elongated flexible member including, along at least a part of its longitudinal axis, at least one projection which, in transversal section, projects from the elongated flexible member; the at least one projection having a distal end and a proximal end, and defining, in transversal section, two lateral sides projecting from the elongated flexible member; and a wire; wherein the at least one projection includes at least one transverse retaining and passing element near the distal end of the projection, the retaining and passing element extending transversely to the lateral sides of the projection; and the wire passes through the retaining and passing element alternatively from one lateral side of the projection to the other lateral side of the projection, where adherence between the wire and the retaining and passing element retains the wire.
US11338103B2	Headgear for a patient interface A positioning and stabilising structure comprising at least one gas delivery tube to receive the flow of air from a connection port on top of the patient's head and to deliver the flow of air to the entrance of the patient's airways via the seal-forming structure, the at least one gas delivery tube comprising a tube wall having an extendable concertina structure comprising a plurality of folds in the tube wall alternatingly forming a plurality of ridges and a plurality of grooves, the folds able to be at least partially unfolded to increase a separation of the ridges to elongate the extendable concertina structure; and one or more ridge connecting portions provided to the tube wall, each of the one or more ridge connecting portions connecting two or more adjacent ridges of the plurality of ridges and being configured to resist the separation of the ridges.
US11338097B2	Active self-locking type syringe An active self-locking type syringe includes a barrel, needle hub, plunger assembly, plunger protection cover, needle cap, needle tube, needle point protection sleeve, spring, guiding limit assemblies, initial clamping assemblies and a trigger ring plug. In an initial state, the trigger ring plug is located in a trigger cavity and is not in contact with the trigger parts or is in contact with the trigger parts but not enough to separate the initial clamping assemblies, the inner wall of the trigger ring plug and the needle hub are sealed, and the outer wall of the trigger ring plug and the inner wall of the barrel are sealed. In the above structure, the trigger ring plug arranged in the trigger cavity is triggered from the interior of the barrel close to a patient end, and the needle point protection sleeve is released.
US11338095B2	Drug delivery device The disclosure relates to a drug delivery device, comprising: a housing to receive a cartridge with a needle and a stopper, wherein the cartridge is movable within the housing so as to cover the needle within the housing or advance the needle beyond the housing, a gas tank containing a pressurized gas within the housing, the gas tank connectable with a cavity for moving the cartridge, a cavity for moving the stopper and a cavity for moving the cartridge, a release member fixed to the housing and adapted to restrict movement of the cartridge relative to the housing in a proximal direction, a membrane between the cavity and the retraction release member adapted to operate the release member if the membrane is deformed by a pressure within the cavity exceeding a predetermined value allowing movement of the cartridge relative to the housing in the proximal direction.
US11338093B2	Dose setting mechanism An injection device comprises a housing having a longitudinal axis, an axially-depressible dose button (430), a dose indicator (418), a dose setting mechanism operatively coupled to said dose indicator and capable of setting a dose to be ejected from the injection device and spring capable of storing energy necessary for ejecting the dose from the injection device. The spring (420) is coupled to the dose setting mechanism such that a charging force can be transferred from the dose setting mechanism to the spring to increase the energy stored by the spring. The dose setting mechanism comprises an assembly of three components, including: •a ratchet ring (410) rotationally and axially locked with respect to said housing, the ratchet ring including a ratchet component; •a drive plate (405) including a first set of splines forming a ratchet arrangement with said ratchet component; and•a dose selector (416) capable of being rotated about said longitudinal axis with respect to said housing to set the dose and including splines for disengaging said ratchet arrangement. The ratchet component is capable of interacting with both the splines on the dose selector and the splines on the drive plate.
US11338091B2	Needleless injector assemblies and related methods A needleless injector assembly can have a spring injector and an ampule. The spring injector can include a housing having a first housing portion and a second housing portion defining a bore and having a casing located in the bore and fixed relative to the first housing portion but the second housing portion can be rotatable relative to the casing. The casing can have a threaded receiving end at an end to threadedly receive a threaded end of an ampule. A pin having an end can project from the second housing portion and into an opening of the first housing portion and wherein the pin is retractable away from the first portion before the second housing portion is rotatable relative to the casing.
US11338089B2	Dose setting mechanism An injection device comprising a housing (12) and a dose selector (16) to set a dose of medicament to be ejected from the injection device. A spring (20) coupled to the dose selector stores energy necessary for ejecting the dose from the injection device. A ratchet (25) arrangement is provided to rotationally couple a ratchet component and an internal surface of the housing in a coupled state and to allow relative rotation between the ratchet component and the internal surface of the housing in an uncoupled state. An over-torque feature (27) located between the dose selector and the spring is actuatable, when the rotation of the dose selector causes the charging force to exceed a defined limit, to reduce the charging force transferred from the dose selector to the spring. Both the ratchet component and the over-torque feature are provided on a single component (28).
US11338083B2	Stimulation of penis erection control A penis erection stimulation system comprises an implantable drug delivery device for delivering a drug to a penis to achieve erection of the penis. An infusion needle of the device is placed outside a left or a right corpus cavernosum in close proximity thereto and advanced into and retracted from, as well as deliver a drug when advanced into, at least one of: the left or right corpus cavernosum, one or two of deep arteries thereof, muscle tissue regulating blood flow through the right, left or both corpus cavernosum and tissue in close proximity to the left, right or both corpus cavernosum. The at least one infusion needle fits in a position in between the left and right corpus cavernosum at a base of the penile tissue placed inside a patient's body where the left and right corpus cavernosum are deviating away from each other.
US11338079B2	Medical instrument A medical instrument for diagnostic, therapeutic, or surgical measures in a cavity in the body of a patient may include a proximal region, which is provided and designed for arrangement outside the body, a distal region, which is provided and designed for arrangement inside a cavity in the body, a supply structure for delivering a fluid to the cavity, wherein the supply structure reaches from a first coupling in the proximal region of the medical instrument to an outlet in the distal region, and a discharge structure for discharging a fluid from the cavity, wherein the discharge structure reaches from an inlet in the distal region of the medical instrument to a second coupling in the proximal region of the medical instrument. The flow resistance of the supply structure is greater than the flow resistance of the discharge structure.
US11338075B2	Split-tip catheter including lateral distal openings A split-tip catheter for placement within the vasculature of a patient and for use in hemodialysis or other suitable procedures, and methods of use. The split-tip catheter can include a catheter body defining a first lumen and a second lumen, and a split distal region extending from a distal end of the catheter body. The split distal region can include an arterial segment defined by an outer wall enclosing an arterial segment lumen, the arterial segment lumen in fluid communication with the catheter body first lumen, and a venous segment defined by an outer wall enclosing a venous segment lumen, the venous segment lumen in fluid communication with the catheter body second lumen, the venous segment outer wall extending from the catheter body distal end to a distal nose portion. The distal nose portion can taper from a first outer perimeter to a second smaller outer perimeter.
US11338073B2	Membrane for an oxygenator for gas exchange in the bloodstream, oxygenator having such a membrane, and method for producing such a membrane The invention relates to an oxygenator for gas exchange in the bloodstream, comprising a housing, a first interior chamber for blood arranged in the housing, a second interior chamber for gas arranged in the housing, and a membrane separating the interior chambers. According to the invention, the membrane has a silicone layer and a reinforcing structure reinforcing the silicone layer.
US11338072B2	Blood treatment systems and related components and methods This disclosure relates to a blood treatment system including a blood treatment machine, a dialyzer configured to be coupled to the blood treatment machine, a blood line having a first end configured to be connected to the dialyzer and a second end configured to be connected to a needle for insertion into a patient, and one or more sensors operable to transmit, to the blood treatment machine, data related to tension along the blood line. The blood treatment machine is configured to take action in response to the data received from the one or more sensors.
US11338071B2	Fluid waste canister A fluid medical waste canister has interior surfaces that are exposed only to compressive stresses when a vacuum is applied, thereby eliminating the potential for environmental stress cracking. The canister is compatible with medical procedures that generate fluids having high fat/lipid content, such as liposuction procedures. The canister avoids certain stress concentration distributions that cause cracks to close onto themselves, which can cause one or more pieces of the canister wall to rupture into its interior volume. Because the canister is designed to avoid conditions that initiate canister implosion during liposuction procedures, low-cost polystyrene may be used as a waste canister material for such procedures.
US11338070B2	Vascular prosthesis for leak prevention during endovascular aneurysm repair An embodiment includes a process for treating an abdominal aortic aneurysm (AAA) endoleak with a shape memory polymer (SMP) foam device. First, a bifurcated stent graft is placed within the aneurysm while a micro guidewire is positioned within the aneurysm for future catheter access. Second, after placing the iliac graft extension, a catheter is introduced over wire to deliver embolic foams. Third, embolic foams expand and conform to the aneurysm wall. Fourth, embolic foams create a stable thrombus to prevent endoleak formation by isolating peripheral vessels from the aneurysm volume.
US11338067B2	Synthetic prosthesis for use in osteo-odonto-keratoprosthesis (OOKP) surgery Disclosed herein is a prosthesis that may be used to replace standard prosthetic material used in osteo-odonto-keratoprosthesis (OOKP) surgery. The disclosed prosthesis is not prepared from tissue removed from a patient's tooth and jaw bone, but rather is a synthetic prosthesis. The synthetic prosthesis typically includes a solid part for supporting an optical cylinder and a porous part that facilitates bio-integration of the implanted prosthesis into the patient's eye.
US11338066B2	Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix Provided are methods for preparing sterilized, gelled, solubilized extracellular matrix (ECM) compositions useful as cell growth substrates. Also provided are compositions prepared according to the methods as well as uses for the compositions. In one embodiment a device, such as a prosthesis, is provided which comprises an inorganic matrix into which the gelled, solubilized ECM is dispersed to facilitate in-growth of cells into the ECM and thus adaptation and/or attachment of the device to a patient.
US11338055B2	Wound dressing This invention relates to a packaged sterile wound dressing comprising a dressing saturated with a pain relieving composition, a method of providing pain relief due to a wound of a subject using said dressing, and a method of manufacturing the packaged sterile wound dressing.
US11338050B2	Safe UV C bulb assembly An excimer bulb assembly including an excimer bulb and a pass filter such that the excimer bulb assembly does not emit substantial UV radiation in wavelengths longer than 231 nm, 232 nm, 233 nm, 234 nm or 235 nm. The wavelengths are measured at an incident angle of zero (0) degrees to the filter plane. The pass filter is preferably constructed of a plurality of layers of hafnium oxide, and most preferably constructed of less than seventy five (75) layers of hafnium oxide. The excimer bulb, pass filter, and two electrical connectors may be adapted to form a cartridge which may be adapted to swivel along its main axis. The cartridge may further include a smart chip. The smart chip may retain and store information regarding the assembly and preferably retains hours of use of the excimer bulb.
US11338044B2	Lipid nanoparticle compositions and methods for mRNA delivery Disclosed herein are compositions and methods for modulating the production of a protein in a target cell. The compositions and methods disclosed herein are capable of ameliorating diseases associated with protein or enzyme deficiencies.
US11338041B2	Exon skipping oligomer conjugates for muscular dystrophy Antisense oligomer conjugates complementary to a selected target site in the human dystrophin gene to induce exon 52 skipping are described.
US11338038B2	Branched multi-functional macromonomers and related polymers and uses thereof Disclosed are methods, compositions, reagents, systems, and kits to prepare and utilize branched multi-functional macromonomers, which contain a ring-opening metathesis polymerizable norbornene group, one or more reactive sites capable of undergoing click chemistry, and a terminal acyl group capable of undergoing a coupling reaction; branched multi-cargo macromonomers; and the corresponding polymers are disclosed herein. Various embodiments show that the macromonomers and polymers disclosed herein display unprecedented control of cargo loading of agents. These materials have the potential to be utilized for the treatment of diseases and conditions such as cancer and hypertension.
US11338034B2	Hydroxyapatite powder and process for producing same, composition based on this powder and process for preparing same and kit comprising this powder The present invention relates to a hydroxyapatite and/or tricalcium phosphate powder characterized in that it has undergone at least one sintering step at a temperature between 400° C. and 600° C. The invention also relates to a process for preparing such a powder, and to a composition comprising such a powder for use as an anti-tumour auto-vaccine and particularly in the treatment of the following pathological conditions: osteosarcoma, B or T lymphoma, mammary tumour, melanoma, haemangiosarcoma, mastocytoma, fibrosarcoma, brain tumours and schwannoma in a subject. The present invention also covers a drug combination comprising the composition of the invention and at least one second therapeutic agent, preferably an anti-tumour agent and/or a radiotherapeutic agent.
US11338033B2	Stabilized group 2 influenza hemagglutinin stem region trimers and uses thereof Vaccines that elicit broadly protective anti-influenza antibodies. The vaccines comprise nanoparticles that display HA trimers from Group 2 influenza virus on their surface. The nanoparticles are fusion proteins comprising a monomeric subunit (e.g., ferritin) joined to stabilized stem regions of Group 2 influenza virus HA proteins. The fusion proteins self-assemble to form the HA-displaying nanoparticles. Also provided are fusion proteins, and nucleic acid molecules encoding such proteins, and assays using nanoparticles of the invention to detect anti-influenza antibodies.
US11338030B2	Multivalent recombinant modified vaccinia virus ankara (MVA) vector encoding filovirus immunogens The present invention relates to an improved filovirus vaccine comprising a recombinant modified vaccinia virus Ankara-based (MVA-based) vaccine against filovirus infection and to related products, methods and uses. Specifically, the present invention relates to genetically engineered (recombinant) MVA and FPV vectors comprising at least one heterologous nucleotide sequence encoding an antigenic determinant of a Marburg virus (MARV) or Ebola virus glycoprotein. Specifically, the invention relates to recombinant MVA comprising Ebola virus glycoprotein and virion protein 40. The invention also relates to products, methods and uses thereof as well as prime/boost regimens of MVA and genetically engineered (recombinant) FPV, e.g., suitable to induce a protective immune response in a subject.
US11338028B2	Cancer vaccines targeting LEMD1 and uses thereof Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a mutated consensus LEMD1 antigen are disclosed. Methods of treating a subject with a LEMD1-expressing tumor and methods of preventing a LEMD1-expressing tumor are disclosed. Mutated consensus LEMD1 antigen is disclosed.
US11338026B2	Identification of immunologically protective neo-epitopes for the treatment of cancers Described herein are methods of identifying immunologically protective neo-epitopes from the cancer tissue DNA of cancer patients using biophysical principles as well as bioinformatics techniques. The identification of immunologically protective neo-epitopes provides pharmaceutical compositions with a limited number of tumor-specific peptides suitable for personalized genomics-driven immunotherapy of human cancer. Specifically disclosed herein is a method of using the conformational stability of an epitope in an MHC protein-binding groove to predict immunogenicity of peptides in a putative neo-peptide set from a tumor from a cancer patient. Pharmaceutical compositions and methods of administration are also included.
US11338022B2	Method for preventing and treating angiocardiopathy The present invention relates to the effect of plasminogen in the treatment and/or elimination of angiocardiopathy, especially angiocardiopathy caused by diabetes mellitus, thereby providing a new strategy for treating different kinds of angiocardiopathy, especially angiocardiopathy and its related disorders caused by diabetes mellitus.
US11338021B2	Combination therapies The invention provides combination therapy for use in treating a bacterial biofilm in a subject comprising (a) a polypeptide having serine protease activity and (b) one or more antibiotic compounds. Also provided are compositions and methods of use of the same.
US11338019B2	Recombinant thrombomodulin domain 1 for use in treating eye diseases associated with pathological ocular angiogenesis The present application relates to dual anti-angiogenic and anti-inflammatory effects of recombinant thrombomodulin domain 1 (TMD1). Specifically, an isolated recombinant polypeptide comprising an amino acid sequence that is at least 80% identical to TMD1 for use in treating an eye disease and/or an eye disorder associated with pathological ocular angiogenesis (POA) in a subject in need thereof is disclosed. The length of the recombinant polypeptide is no more than 200 amino acid residues. The eye disease and/or the eye disorder may be at least one selected from the group consisting of retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. Use of TMD1 in the manufacture of a medicament for treating an eye disease and/or an eye disorder associated with vascular endothelial growth factor (VEGF)-induced ocular angiogenesis and/or hypoxia-inducible factor-1α (HIF-1α)-VEGF pathway is also disclosed.
US11338018B2	Adrenocorticotropic hormone-based pharmaceutical formulations and methods for fabricating and using thereof Pharmaceutical compositions for treating, mitigating or preventing autoimmune diseases and associated conditions are described herein. Methods for fabricating the compositions and using them are also described.
US11338015B2	Therapy for subarachnoid hemorrhage and ischemia The application provides data from a clinical trial of a PSD-95 inhibitor in subjects undergoing endovascular repair of an aneurysm in or otherwise affecting the CNS. The subjects were stratified by whether the aneurysm ruptured before performing the endovascular surgery. Rupture is associated with higher mortality or increased debilitation if a subject survives. The trial provided evidence of significant benefit in subjects with and without aneurysm rupture before endovascular was surgery performed. Surprisingly, the subjects benefitting most from treatment as judged both by pathology and neurocognitive outcome were those in which the aneurysm had ruptured causing a subarachnoid hemorrhage. These data constitute evidence that a PSD-95 inhibitor is beneficial not only in ischemic and hemorrhagic stroke but in forms of hemorrhage in or affecting the CNS, particularly, subarachnoid hemorrhage.
US11338009B2	Compositions and methods for treatment of hereditary cystatin C amyloid angiopathy (HCCAA) and other neurodegenerative disorder associated with aberrant amyloid deposits Compositions and methods for the treatment of amyloid deposit diseases, e.g., hereditary cystatin C amyloid angiopathy and other neurodegenerative disorders, are disclosed.
US11338003B2	Methods of treating bladder cancer with an oncolytic virus The present invention provides methods for treating an individual having bladder cancer comprising intravesically administering to the individual an oncolytic virus. Also provided are pharmaceutical compositions and kits for treating bladder cancer.
US11338002B2	Use for treatment of clostridium difficile infections The present invention relates to the use of specific strains of Lactobacillus paracasei or of a composition comprising said strains for the prevention and/or treatment of a physiopathological condition related to/associated with Clostridium difficile infection, preferably intestinal infections, or so-called CD-associated disease (CDAD) or CD infection (CDI).
US11338001B2	Probiotics for aggregation with disease-associated species in the oral cavity The present invention relates to certain microorganisms or mixtures thereof for use in the treatment and/or prevention of inflammation in the oral cavity, preferably for the treatment and/or prevention of gingivitis and/or peridontitis.In particular, the present invention relates to microorganisms or mixtures thereof for use as probiotic agents for forming co-aggregates with microorganisms associated with gingivitis and/or peridontitis.Furthermore, the present invention provides oral pharmaceutical compositions, oral care products or products for nutrition or pleasure comprising one or more of the probiotic microorganisms as active agents as well as a method of production thereof.
US11337996B2	Clay product and uses thereof The present invention relates to a combination of an anti-toxin, The present invention relates to a combination of an anti-toxin, an immunomodulator and a component that provides energy to mucosal cells, which may be useful for decreasing effects of Clostridia sp. or coccidia sp based diseases or other enteric diseases or by generally improving gastro intestinal health or function.
US11337989B2	Compositions and methods for inhibiting inflammation and diseases using an alginic acid-based antimicrobial compound The present disclosure relates to compositions and methods for inhibiting inflammation and reducing the risk of spreading sexually transmitted diseases using an alginic acid-based antimicrobial compound. Such compositions provide dual protection by (1) attacking and inactivating viruses and other microbes and (2) blocking the host response that viruses trigger to invade host cells. Such compositions can also be part of an acid buffering contraceptive.
US11337988B2	Use of ouabain antagonists to inhibit viral infection Embodiments of a method for inhibiting viral infection in a subject are provided herein. In some embodiments, the method comprises administration of a competitive antagonist of ouabain binding to ATP1A1 to inhibit respiratory syncytial virus infection in the subject.
US11337986B2	Dietary supplement A method of forming a dietary supplement can include steps of creating a composition of matter comprising tianeptine, CDP Choline, and optionally, Alpha GPC; and providing the composition of matter in a liquid or solid form. The ingredient of tianeptine can be tianeptine sodium, tianeptine free acid, or both. Providing the composition of matter can include filling a container with the composition of matter.
US11337984B2	Methods for treating, diagnosing and prognosing a haematological malignancy The invention relates to a serotonin receptor (5-HTR) inhibitor selected from the group consisting of a type 1 5-HTR inhibitor and a type 2 5-HTR inhibitor for use in the prevention and/or treatment of a haematological malignancy. Additionally, the invention relates to in vitro methods for the identification or isolation of a malignant cell from a haematological malignancy or for diagnosing a haematological malignancy based on detecting the expression of type 1 5-HTR and/or type 2 5-HTR. Furthermore, the invention relates to in vitro methods for determining the prognosis, for monitoring the effect of a therapy or for designing a customized therapy in a subject suffering from a haematological malignancy based on determining the levels of type 1 5-HTR and or type 2 5-HTR.
US11337980B2	Treatment of mitochondrial diseases The present invention provides a composition comprising one or more deoxyribonucleosides for use in the treatment of a mitochondrial DNA depletion and/or multiple deletions syndrome provided that the syndrome is not caused by a defect in the deoxyribonucleoside triphosphate (dNTP) metabolism. With the use of the invention there is a recovery in mitochondrial DNA levels independently from the severity of the patient's disease, which confers a great therapeutic value to the invention.
US11337976B2	Compounds and methods for kinase modulation, and indications therefor Compounds active on protein kinases are described, as well as methods of making and using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
US11337975B2	Pharmaceutical combinations comprising a histone deacetylase inhibitor and a CD38 inhibitor and methods of use thereof The present disclosure relates to a pharmaceutical combination comprising (a) a histone deacetylase inhibitor and (b) a CD38 inhibitor, including combined preparations and pharmaceutical compositions thereof; uses of such combination in the treatment or prevention of cancer; and methods of treating or preventing cancer in a subject comprising administering a therapeutically effective amount of such combination.
US11337972B2	Pharmaceutical preparation and use thereof A pharmaceutical preparation includes a first active component, a second active component and pharmaceutically acceptable excipients. The first active component is at least one selected from the group consisting of a neutral endopeptidase inhibitor and a precursor, an active metabolite, a stereoisomer, a pharmaceutically acceptable salt, a prodrug and a solvate thereof. The second active component is at least one selected from the group consisting of a compound represented by the following formula (I) or a precursor, an active metabolite, a stereoisomer, a pharmaceutically acceptable salt, a prodrug and a solvate thereof. The pharmaceutically acceptable excipients include one or more disintegrants and/or one or more fillers.
US11337967B2	Methods of treatment The present disclosure provides for methods of treating a patient with a CYP3A4 substrate drug, wherein the patient is treated with posaconazole. In some embodiments, the patient stops posaconazole treatment, waits for at least 2 days, and then is treated with the CYP3A4 substrate drug as soon as it is safe to do so. In some embodiments, treatment with the CYP3A4 substrate drug is delayed for about 2-42 days after stopping posaconazole. In some embodiments, the patient is treated with a reduced dose of the CYP3A4 substrate drug for about 2-42 days.
US11337965B2	Kinase mutation-associated neurodegenerative disorders The present technology relates to methods for treating, preventing, and/or ameliorating kinase mutation-associated neurodegenerative diseases, including BRAFV600E-associated neurodegenerative diseases, in a subject in need thereof. In particular aspects, the present technology relates to the use of BRAF, MEK, and/or CSF-IR inhibitors to treat, prevent, and/or ameliorate kinase mutation-associated neurodegenerative diseases, including BRAFV600E-associated neurodegenerative diseases.
US11337958B2	Compositions and methods of treating and reducing risk of conditions associated with elevated 4-ethylphenyl sulfate Compositions and methods are disclosed for treating anxiety or stress in an animal, for reducing elevated levels of 4-EPS in an animal with elevated 4-EPS levels, for preventing elevated levels of 4-EPS in an animal and for promoting growth of beneficial microbes in an animal's microbiome and inhibiting growth of non-beneficial microbes. The methods comprise administering to the animal an effective amount of soy protein and vitamin C. Compositions are disclosed which comprise amounts of soy protein and vitamin C effective for use in the methods.
US11337950B2	Biologically active cannabidiol analogs Biologically active cannabidiol analogs comprising a compound of the formula wherein one of R1 or R2 or both is/are the residue of a moiety formed by the reaction of an amino group of the amino acid ester of R1 or R2 or both with a dicarboxylic acid or a dicarboxylic acid derivative and the other R1 or R2 (in the case of the mono) is the residue of a dicarboxylic acid or dicarboxylic acid derivative or Hydrogen (H), (i.e. underivatized), and salts thereof. These CBD analogs are be useful in pain management in oncology and other clinical settings in which neuropathy is presented. Furthermore, these CBD-analogs are useful in blocking the addictive properties of opiates.
US11337948B2	Compositions and methods comprising C16:1N7-palmitoleate One embodiment described herein is related to methods and compositions, such as nutraceutical formulations and dietary supplements, comprising C16:1n7-palmitoleate or derivatives thereof. The methods and compositions comprising C16:1n7-palmitoleate, or derivatives thereof, safely and effectively prevent or mitigate manifestations of cardiovascular disease, including coronary artery disease and the accumulation of cholesterol or lipid deposits in the blood vessels of a subject.
US11337945B2	C5 ketone compositions, and related methods, for therapeutic and performance supplementation The present disclosure pertains to compositions and methods for the treatment and/or prevention of one or more of obesity, diabetes, metabolic syndrome, Alzheimer's disease, Chronic Fatigue Syndrome (CFS), aging, fibromyalgia, dyslipidemia, hypercholesterolemia, dyslipidemia, Parkinson's disease, migraines, Traumatic Brain Injury (TBI), Attention Deficit Disorder (ADD)/Attention Deficit Hyperactivity Disorder (ADHD), Cancer, Cardiovascular Disease (CVD)/Coronary Artery Disease (CAD), Chronic Pain, neuralgia, depression, amyotrophic lateral sclerosis (ALS), and epilepsy, Insufficient Cellular Energy (ICE) and mitochondrial dysfunction. The present disclosure also pertains to methods for increasing mental and/or physical performance levels and/or decreasing exertion during exercise in a subject by the administration of C5 ketones.
US11337942B2	External use composition comprising paeonol and panthenol or pharmaceutically acceptable salts thereof as active ingredients Provided are a medical ointment of a novel combination containing paeonol and a pharmaceutical use thereof. The medical ointment of a novel combination includes paeonol and panthenol, and further includes at least one selected from Centella asiatica, coenzyme Q10, neomycin sulfate, and pharmaceutically acceptable salts of these. In the medical ointment of a novel combination, specific ingredients that are effective for local pain relief are mixed with ingredients having other effects in a certain ratio to address the problems of the cut treatment ointment of the related art, so that excellent effects may be obtained in relieving itching and reducing pain while inflammation is effectively treated.
US11337940B2	Articles with active agent concentrated at the substrate contacting surface and related methods Compositions and methods to produce adhesive articles with active agents concentrated at the substrate contacting surface. The active agents are applied in powder form, or in combination with a liquid or gel vehicle, to the substrate contacting surface of an adhesive layer of an adhesive article. The active agent compositions are directly applied to the adhesive layer, or are first applied to a release liner, which is then brought into contact with the adhesive layer to dispose the active agent compositions to the substrate contacting surface of the adhesive layer. Upon application of the adhesive article to a substrate, the active agent is delivered to a region of interest on the substrate.
US11337939B2	Dapsone formulations and methods of using same A method for treating patients with COVID-19 and/or other respiratory conditions include administering a dosage of 75-100 milligrams of dapsone twice daily. A variety of dapsone formulation and delivery devices are disclosed, including an inhaler, nasal spray, nasal gel, otic formulation, intravenous formulation, oral solution, oral suspension, patch and suppository.
US11337933B2	Compositions and methods for treatment of erectile dysfunction The subject invention pertains to methods and compositions for the treatment of erectile dysfunction (ED) (e.g., impotence) in a subject in need thereof utilizing one or more cannabinoid and one or more anti-ED drug.
US11337932B2	Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene The present invention relates to a transdermal therapeutic system (TTS) for the transdermal administration of asenapine comprising a self-adhesive layer structure comprising a therapeutically effective amount of asenapine, said self-adhesive layer structure comprising: A) a backing layer; B) an asenapine-containing layer comprising: 1. asenapine in the form of the free base; and 2. a polymer selected from the group consisting of polysiloxanes and polyisobutylenes in an amount of more than 50% by weight based on the total weight of the asenapine-containing layer; and C) optionally an additional skin contact layer.
US11337929B2	Drug delivery formulation for treating mental illness or central nervous system disorder A drug delivery formulation for treating a mental illness or a central nervous system disorder is disclosed. The drug delivery formulation includes a microcapsule containing a biodegradable polymer and a drug and a crosslinked hydrogel and a method for preparing the same. The drug delivery formulation can slowly release a drug at a constant rate without a burst of drug release in the early stage of drug administration to maintain a constant blood drug level over a long period of time and thus enjoys the advantage of preventing excessive initial release of drug, thereby obtaining a desirable sustained release profile by single administration without necessity for multiple administrations divided at regular time intervals.

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