Document Document Title
US11261501B2 Detection method for Neisseria gonorrhoeae
A method of detecting the presence of Neisseria gonorrhoeae in a sample. The method involves detecting a first target sequence taken from the NGO1642 gene and/or a second target sequence taken from the NGO1012 gene. The method may involve a step of amplifying the target sequence, and may involve hybridising the target sequence to a nucleic acid probe and identifying hybridisation. The method may involve simultaneous detection of other target sequences, e.g. from other pathogens.
US11261496B2 Methods for detecting prostate cancer by determining the ratio of early to late endosomal markers
Methods for detecting a prostate cancer in a subject comprise detecting a marker selected from an endosomal associated marker and/or a lysosomal associated marker from the subject.
US11261495B2 Assessment of the PI3K cellular signaling pathway activity using mathematical modelling of target gene expression
The present invention relates to a method comprising inferring activity of a PI3K cellular signaling pathway in a tissue and/or cells and/or a body fluid of a medical subject based at least on expression levels of one or more target gene(s) of the PI3K cellular signaling pathway measured in an extracted sample of the tissue and/or the cells and/or the body fluid of the medical subject. The present invention further relates to an apparatus comprising a digital processor configured to perform such a method, a non-transitory storage medium storing instructions that are executable by a digital processing device to perform such a method, and a computer program comprising program code means for causing a digital processing device to perform such a method.
US11261494B2 Method of measuring a fractional concentration of tumor DNA
A frequency of somatic mutations in a biological sample (e.g., plasma or serum) of a subject undergoing screening or monitoring for cancer, can be compared with that in the constitutional DNA of the same subject. A parameter can derived from these frequencies and used to determine a classification of a level of cancer. False positives can be filtered out by requiring any variant locus to have at least a specified number of variant sequence reads (tags), thereby providing a more accurate parameter. The relative frequencies for different variant loci can be analyzed to determine a level of heterogeneity of tumors in a patient.
US11261487B2 Hairpin loop method for double strand polynucleotide sequencing using transmembrane pores
The claimed invention relates to a method of processing a polynucleotide, by obtaining a sense polynucleotide strand comprising a homopolymeric region that is longer that the reading section of a nanopore; synthesizing an antisense polynucleotide strand under conditions in which a nucleotide analog is incorporated at random in a reverse complement of the homopolymer region, such that the length of the homopolymer region in the antisense polynucleotide strand is shorter than the reading section of the nanopore; and moving the antisense polynucleotide strand through the nanopore such that a proportion of the antisense polynucleotide strand interacts with the nanopore.
US11261484B2 Biomolecule analysis kit and biomolecule analysis method
A biomolecule analysis kit includes a reaction container configured to perform an enzymatic reaction, the reaction container including a base portion which has a container-shaped portion and a low-adsorption structural portion which is provided on at least the inner surface of the container-shaped portion, the low-adsorption structural portion having an adsorption rate lower than the base portion at which at least one of a sample which becomes a target of analysis in the enzymatic reaction and a reagent for the enzymatic reaction is adsorbed thereonto, wherein a signal resulting from the enzymatic reaction is configured to be detected when the enzymatic reaction is performed in the reaction container.
US11261481B2 Probes for improved melt discrimination and multiplexing in nucleic acid assays
Methods and compositions for the detection and quantification of nucleic acids are provided. In certain embodiments, methods involve the use of primers or probes that comprise a non-natural nucleotide linked to a reporter. Target nucleic acids are detected by the polymerization of a complementary probe or primer that incorporated a cognate non-natural nucleotide linked to a quencher.
US11261480B2 Nucleic acid preparation method
A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C2-C10 alkanediol.
US11261478B2 Thermal stable luciferase with improved resistance to inhibition by luciferin break-down products
Provided herein are inhibitor-resistant luciferase mutants, and methods of use thereof. In particular, luciferase mutants are provided that are thermal stable and exhibit improved stability in the presence of luciferin break-down products, such as dehydroluciferin. Further provided are assay systems comprising inhibitor-resistant luciferase mutants and amino acid sequences of the inhibitor-resistant luciferase mutants.
US11261476B2 Method for recovering microbial cells
The present invention provides a method of recovering viable microbial cells from a complex sample, said method comprising: a) providing a sample having a volume of at least 1 ml; b) contacting said sample with a buffer solution and one or more proteases, wherein said buffer solution has a pH of at least pH 6 and less than pH 11, wherein said buffer solution and said one more proteases do not comprise a detergent or a chaotrope, and wherein the buffer solution/protease/sample mixture is non-hypotonic; c) filtering the mixture obtained in step (b) through a filter suitable for retaining microbial cells; and d) recovering the microbial cells retained by the filter in step (c), wherein the recovered microbial cells are viable, and a microbial recovery device for the same.
US11261473B2 Method and apparatus for generation of microparticles containing immobilized enzyme
A method and an apparatus are described for the generation of microparticles containing an immobilized functional component, where the following measures are proposed: spraying a liquid (32) containing a soluble alginate and a functional component consisting of molecules or nanoparticles to generate a stream (60) of droplets, directing the stream (60) of droplets onto a precipitation bath (16) and capturing the droplets therein by application of high voltage (14), precipitating the droplets in the precipitation bath (16) via a precipitation liquid (18) containing an alginate complexing agent, such that the droplets are solidified to form microparticles (10) containing the functional component and extracting the microparticles (10) from the precipitation bath (16).
US11261471B2 Methods and compositions for making vault particles in yeast
Disclosed herein are methods and compositions for making vault particles in yeast hosts and yeast vaults produced therefrom.
US11261467B2 Thermal decomposition of magnesium chloride
A method for conversion of magnesium chloride into magnesium oxide and HCl, comprising the steps of providing a magnesium chloride compound to a thermohydrolysis reactor, the reactor being at a temperature of at least 300° C., withdrawing MgO from the thermohydrolysis reactor in solid form, and withdrawing a HCl containing gas stream from the thermohydrolysis reactor, wherein the magnesium chloride compound provided to the thermohydrolysis reactor is a solid magnesium chloride compound which comprises at least 50 wt. % of MgCl2.4H2O. The process accordingly is fast and can be operated in a manner which is efficient both as regards apparatus and energy. It can also be integrated in a process for converting a magnesium chloride solution.
US11261465B2 Method and system for incorporation of biomolecules into vesicles, cells, and micelles using electroactive porous device membrane
A method and system of delivering a charged cargo, such as a biomolecule, to a target structure, such as cells, exosomes, other vesicles or micelles, using an electroactive porous membrane. This method comprises contacting an electroactive porous membrane with a fluid flow toward the membrane. The fluid contains charged biomolecules and the membrane and biomolecules are oppositely charged so that the biomolecules in the fluid are trapped on the membrane as the fluid flows through the pores of the membrane. Acceptor cells of interest are pinned to the membrane by the flow of the fluid, thereby aggregating the cells onto the membrane in close proximity to the trapped biomolecules. Finally, the acceptor cells are permeabilized.
US11261464B2 Promoters
The present invention relates to the field of (vector) vaccines, and especially to novel promoter sequences, expression cassettes and vectors, which are suitable to express genes of interest, especially antigen encoding sequences. The viral vectors of the present invention are useful for producing an immunogenic composition or vaccine.
US11261461B2 Methods and compositions for selective generation of dopaminergic precursors
Provided are methods and compositions for transdifferentiation of a somatic cell, e.g., a fibroblast to a dopaminergic precursor, Specifically, provided are induced dopaminergic (iDP) cells, or master transcription factors (TFs) therefore, methods for making iDP cells, and methods and compositions for using them in, e.g., treating neurodegenerative diseases such as Parkinson's disease.
US11261458B2 Potyvirus resistance genes and methods of use
Compositions and methods and for enhancing the resistance of plants to plant diseases caused by potyviruses are provided. The compositions comprise nucleic acid molecules encoding resistance (R) gene products and variants thereof and plants, seeds, and plant cells comprising such nucleic acid molecules. The methods for enhancing the resistance of a plant to plant disease caused by a potyvirus comprise introducing a nucleic acid molecule encoding an R gene product into a plant cell. Additionally provided are methods for using the plants in agriculture to limit plant disease.
US11261454B2 Method for introducing a polynucleotide into non-adhesively growing plant cells
The present invention relates to a method for introducing a polynucleotide into non-adhesively growing plant cells, comprising the following steps: providing a solid support having immobilized thereto the polynucleotide in dry state; contacting the plant cells with the polynucleotide on the solid support so as to obtain transformed plant cells; and optionally washing the plant cells.
US11261449B2 Anti-cancer RNA aptamers
Provided herein, inter alia, are compounds capable of binding HSP70 (e.g. mHSP70) on a cell and internalizing into said cell. The compositions provided herein may be useful for delivering therapeutic and diagnostic agents to a cell. Further provided are pharmaceutical compositions and methods of treatment using nucleic acid compounds provided herein.
US11261447B2 Methods for inhibition of HAO1 (hydroxyacid oxidase 1 (glycolate oxidase)) gene expression
The invention relates methods of using RNAi agents to inhibit expression of HAO1 and methods of treating subjects having, e.g., PH1.
US11261444B2 Organic compositions to treat EPAS1-related diseases
The present disclosure relates to methods of treating EPAS1-related diseases such as cancer, metastases, astrocytoma, bladder cancer, breast cancer, chondrosarcoma, colorectal carcinoma, gastric carcinoma, glioblastoma, head and neck squamous cell carcinoma, hepatocellular carcinoma, lung adenocarcinoma, neuroblastoma, non-small cell lung cancer, melanoma, multiple myeloma, ovarian cancer, rectal cancer, renal cancer, clear cell renal cell carcinoma (and metastases of this and other cancers), gingivitis, psoriasis, Kaposi's sarcoma-associated herpesvirus, preeclampsia, inflammation, chronic inflammation, neovascular diseases, and rheumatoid arthritis, using a therapeutically effective amount of a RNAi agent to EPAS1.
US11261441B2 Vectors and compositions for treating hemoglobinopathies
The invention provides improved gene therapy vectors, compositions, and methods.
US11261440B2 Antisense oligonucleic acid
The present invention aims to provide an antisense oligonucleic acid with reduced hepatotoxicity. The antisense oligonucleic acid according to the present invention is characterized in that it has a base length of not less than 7 nt and not more than 30 nt, wherein nucleic acid residues of not less than 1 nt and not more than 5 nt respectively from the both terminals are 2′,4′-bridged nucleic acids, 2′,4′-non-bridged nucleic acid residue(s) is(are) present between the above-mentioned both terminals, and one or more bases in the nucleic acid residue(s) of the above-mentioned 2′,4′-non-bridged nucleic acid residue(s) is/are modified.
US11261435B2 Chemical-inducible genome engineering technology
The present disclosure refers to an endonuclease-based gene editing construct, wherein the construct comprises a CRISPR-associated endonuclease (such as Cas9 or Cpf1) or a derivative thereof and at least one or more hormone binding domains of the estrogen receptor (ERT2) or derivatives thereof. The present disclosure also describes a method of editing a genome of a host cell using the construct as disclosed herein, the method comprising transfecting the host cell with the nucleic acid sequence as defined herein and incubating the cell with an inducing agent.
US11261433B2 Autosomal-identical pluripotent stem cell populations having non-identical sex chromosomal composition and uses thereof
An article of manufacture is disclosed which comprises at least two populations of autosomal-identical induced pluripotent stem cells (iPSCs), wherein the complement of sex chromosomes of the first population of the at least two populations is non-identical to the complement of sex chromosomes of the second population of the at least two populations. Uses thereof and methods of generating same are also disclosed.
US11261431B2 Crushed stem cell extract (shelled stem cell) manufacturing method using mass culture medium composition method and constituent 3-low extracting method and a treating composition for anti-inflammatory and a treating composition for cell regeneration
Disclosed is a method of manufacturing a medium composition for cell culture, and a method of manufacturing a crushed stem cell extract using a method of manufacturing a medium composition for cell culture and a 3-low extracting method of active ingredients of a stem cell. The medium composition for cell culture includes a basal medium; a hyaluronic acid; and an additive composition. According to an embodiment, when active ingredients of a stem cell are extracted, a stem cell is crushed at a 3-low circumstance of low temperature, low pressure, a hypotonic circumstance.
US11261430B2 Hematopoietic stem and progenitor cells derived from hemogenic endothelial cells
Embodiments herein relate to in vitro production methods of hematopoietic stem cell (HSC) and hematopoietic stem and progenitor cell (HSPC) that have long-term multilineage hematopoiesis potentials upon in vivo engraftment. The HSC and HSPCs are derived from pluripotent stem cells-derived hemogenic endothelia cells (HE).
US11261428B2 Gene-regulating compositions and methods for improved immunotherapy
The present disclosure provides methods and compositions related to the modification of immune effector cells to increase therapeutic efficacy. In some embodiments, immune effector cells modified to reduce expression of one or more endogenous target genes, or to reduce one or more functions of an endogenous protein to enhance effector functions of the immune cells are provided. In some embodiments, immune effector cells further modified by introduction of transgenes conferring antigen specificity, such as exogenous T cell receptors (TCRs) or chimeric antigen receptors (CARs) are provided. Methods of treating a cell proliferative disorder, such as a cancer, using the modified immune effector cells described herein are also provided.
US11261423B2 Compartmented cryopreservation container and uses thereof
Described are medical products, methods, and cryogenic bags or other containers suitable for storing and/or transporting and/or processing cellular compositions and other related materials. In certain aspects, the contents of such cryogenic bags may be warmed, mixed, and applied to a patient. Medical products described herein find particular use in treating diseased and/or damaged tissue such as in wound repair and/or bone repair. Related methods of manufacture are also described.
US11261422B2 Culture medium composition for suspension culture allowing easy cell recovery, and cell recovery method
The present invention provides a medium composition containing deacylated gellan gum or a salt thereof, and an acidic polysaccharide or a salt thereof capable of maintaining a random coil state in a divalent metal cation medium and cross-linking via a divalent metal ion, and permitting culture of a cell or a tissue in suspension, wherein a concentration of the deacylated gellan gum or a salt thereof in the medium composition is 0.002-0.01 (w/v) %, a concentration of the acidic polysaccharide or a salt thereof is 0.004-0.1 (w/v) %, and a mass ratio of the acidic polysaccharide or a salt thereof to the deacylated gellan gum or a salt thereof is not less than 1. In addition, the present invention provides a method for isolating a cell or tissue from a culture preparation containing the medium composition and cell or tissue, including applying a shear force to the culture preparation.
US11261417B2 Bioreaction container
A bioreaction container including a culture chamber configured to contain a culture solution and a life form in an inner space, the culture chamber having an open upper end; a chamber cover portion coupled to the upper end of the culture chamber, the chamber cover portion having a protruding tube provided on one side thereof so as to communicate with the inner space; a filter cap coupled to the protruding tube in an attachable/detachable manner so as to open/close the protruding tube; a gas introduction portion configured to penetrate the chamber cover portion and to communicate with the inner space so as to supply a predetermined gas into the inner space; and an acidity/basicity adjustment portion installed on the chamber cover portion while containing an adjustment solution that adjusts pH of the culture solution such that the adjustment solution is discharged into the inner space by pneumatic pressure.
US11261415B2 Reactor systems
This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals. In some embodiments, reactor systems comprising a mobile carriage assembly; a disposable reaction container removably attached to the carriage assembly; and, a carriage holder into which the mobile carriage assembly may be removably inserted are provided.
US11261409B2 Tablet production
The invention relates to stable, anhydrous concentrated formulations in tablet form and methods of making stable, anhydrous concentrated formulation tablets.
US11261403B2 Stabilized compositions comprising leuco compounds
A composition comprising: (a) a leuco composition; and (b) a stabilizing amount of an antioxidant composition. The antioxidant composition comprises at least one sterically hindered phenol and at least one substituted diarylamine, and the mole ratio of the hindered phenol to the substituted diarylamine is greater than 1:1. In another embodiment, a composition comprises (a) a leuco composition and (b) an antioxidant composition; and optionally (c) a solvent composition. The combined mass of the leuco compounds and antioxidants present in the composition is 10% or more of the total mass of the composition, and (b) the molar ratio of antioxidants present in the composition to leuco compounds present in the composition is greater than 1:1.
US11261398B2 Hydraulic fluid composition
A hydraulic fluid includes an oil of lubricating viscosity and at least 2 wt. % of an ester of a carboxy group-containing interpolymer comprising units derived from a vinyl aromatic monomer and units derived from a carboxylic acid monomer. The interpolymer also contains nitrogen functionality. The hydraulic fluid is at least substantially free of polyacrylates and polymethacrylates.
US11261397B2 Lubricant composition for plastic processing
Provided is a lubricant composition for plastic working which lubricant composition is excellent in lubricity and mold releasability. The lubricant composition for plastic working which lubricant composition contains: (a) silica; and (b) an alkali metal salt of an organic acid, a weight ratio of (b) the alkali metal salt of the organic acid to (a) the silica (a weight of (b)/a weight of (a)) being not less than 2, is used.
US11261395B2 Fullerene compound, lubricant for magnetic recording medium, and magnetic recording medium
The invention provides a fullerene compound; a lubricant that is for a magnetic recording medium and that contains the fullerene compound; and a magnetic recording medium. The fullerene compound is an ionic liquid that is represented by general formula (1) and is formed from a Bronsted acid (Hn1X) and a Bronsted base ([R2R3)N—]m1—R1); wherein one of the Brønsted acid and the Broønsted base contains a group having a fullerene; and the other contains a perfluoroalkyl chain.
US11261392B2 Aqueous polymer dispersions, a method for their preparation and the use thereof as pour-point depressants for crude oil, petroleum, and petroleum products
The invention relates to aqueous polymer dispersions comprising at least one polymer obtainable by the reaction of at least one monomer M1 of the general formula (I): H2C═CH—C(O)OR, wherein R is an unbranched alkyl chain comprising from 18 to 22 carbon atoms, and optionally at least one monomer M2. The invention relates moreover to a method for the preparing of such aqueous polymer dispersion and the use thereof as pour point depressant for crude oil, petroleum, and petroleum products.
US11261390B2 Apparatus and method of preparing synthetic fuel using natural gas
Disclosed is an apparatus and method of preparing synthetic fuel using natural gas extracted from a stranded gas field on land or at sea as a raw material through a compact GTL process or a GTL-FPSO process. A parallel-type gas purification unit for controlling a molar ratio of synthetic gas and a concentration of carbon dioxide in the synthetic gas, in which a CO2 separation device and a bypass unit are disposed in parallel, is provided and, thus, the gas purification unit may prepare the synthetic gas by a steam carbon dioxide reforming (SCR) reaction using natural gas having different CO2 contents of various stranded gas fields and then supply the synthetic gas having an optimum composition suitable for a Fischer-Tropsch synthesis.
US11261388B2 Conversion of crude oil to aromatic and olefinic petrochemicals
A system includes a hydroprocessing zone configured to remove impurities from crude oil; a first separation unit configured to separate a liquid output from the hydroprocessing zone into a light fraction and a light fraction; an aromatic extraction subsystem configured to extract aromatic petrochemicals from the light fraction; and a fluid catalytic cracking unit configured to crack the heavy fraction into multiple products.
US11261379B1 Fire-retardant potting compound for backlit devices
A fire-retardant potting compound for a backlit device is disclosed. The fire-retarding potting compound includes a white resin, an Aluminum Trihydroxide powder, and a hardener mixed together. The fire-retardant potting compound may be applied to a panel of a backlit device, in between a light source and one or more transmissive features of the panel.
US11261377B2 Photoactive polymer materials
The present invention relates to novel photoactive polymer materials and their use as orienting layer for liquid crystals, which are used for the production of non-structured and structured optical elements or electro-optical elements and multi-layer systems.
US11261374B2 Squarylium compound, light-emitting composition, and light-emitting film
The present invention addresses the issue of providing: a novel squarylium compound that has high light-emission efficiency, in particular little reduction in light-emission efficiency in a solid membrane, and is capable of emitting a near-infrared light having excellent light resistance; and a light-emitting composition and a light-emitting film that contain said squarylium compound. This squarylium compound is characterized by having a structure indicated by general formula (1).
US11261373B2 Preparation method of supercritical carbon dioxide thickener for tight oil and gas reservoir
The present invention disclosed a method for preparing a thickener for tight oil and gas reservoir, which relieves damages. The technical solution includes the following steps: putting a three-flask in ice; adding perfluoroalkyl alcohol, P-toluenesulfonyl chloride and pyridine; reacting for 3 h at 0-20° C.; adding filter paper; ultrasonic dispersing for 1 h; removing the filter paper; washing the solution for 3-5 times by adding dilute hydrochloric acid to collect the intermediate product (I); adding 1,3-dihydroxy-propane-2-tert-butyl carbamate and the intermediate product (I) in another three-flask; adding potassium carbonate and N,N-dimethylformamide; reacting for 4 h at 40° C. to collect the intermediate product (II); adding trifluoroacetic acid and methylene chloride into the intermediate product (II); reacting at 45° C. for 2 h; extracting and vacuum drying; and adding 1,6-hexamethylene diisocyanate; reacting for 2 h to collect the final product (III).
US11261370B2 Scale deposition inhibiting scavenger compositions and their use
A method of treating a fluid to reduce the level of H2S therein while inhibiting the deposition of scale on surfaces in contact with the fluid, comprising introducing into the fluid a triazine scavenger compound and a terpolymer. The fluid may be liquid or gas and may be petroleum, petroleum product, natural gas, liquefied petroleum gas or other type of oil fraction or refined oil. The triazine scavenger may be e.g. 1,3,5-tri(2-hydroxyethyl)-hexahydro-1, 3, 5-triazine. The terpolymer may comprise a carboxylate/sulphonate/non-ionic terpolymer. When added to a wellbore fluid, it is effective as a scavenger of H2S and also reduces the amount of scale deposition on a surface in contact with the fluid when the fluid comes into contact with or is mixed with a brine. In some aspects, the composition increases the proportion of precipitated solids held in suspension when the fluid is contacted with or mixed with a brine.
US11261368B2 Silicon dioxide Janus nanosheets relative permeability modifier (RPM) for reducing subterranean formation water permeability in carbonate and sandstone formations
A silicon oxide Janus nanosheets relatively permeability modifier (RPM) for carbonate and sandstone formations. The silicon oxide Janus nanosheets RPM may be used to treat a water and hydrocarbon producing carbonate or sandstone formation to reduce water permeability in the formation and increase the production of hydrocarbons. The silicon oxide Janus nanosheets RPM for carbonate formations includes a first side having negatively charged functional groups and a second side having alkyl groups. The silicon oxide Janus nanosheets RPM for sandstone formations includes a first side having positively charged functional groups and a second side having alkyl groups. The negatively charged functional groups may include a negatively charged oxygen group groups and hydroxyl groups. The positively charged functional groups may include amino groups and an amine. Methods of reducing water permeability using the silicon oxide Janus nanosheets RPM and methods of manufacturing the silicon oxide Janus nanosheets RPM are also provided.
US11261362B2 Stabilization and reduction of TCT of brines containing monovalent iodides
A composition for use in a wellbore activity, the composition comprising a stabilized monovalent iodide brine, the stabilized monovalent iodide brine comprises a monovalent salt system, the monovalent salt system comprises a monovalent iodide; a primary iodide stabilizer, the primary iodide stabilizer operable to remove free iodine, prevent the formation of free iodine, and suppress TCT; and an aqueous fluid, where the stabilized monovalent iodide brine has a density greater than 10 lb/gal, where the stabilized monovalent iodide brine has a TCT of less than or equal to 70 deg F.
US11261361B2 Salt tolerant friction reducer
A friction reducing treatment solution that includes water, from 100 to 500,000 ppm of total dissolved solids, and from 0.5 to 3 gallons per thousand gallons of a water-in-oil emulsion containing a water soluble polymer. The total dissolved solids include at least 10 weight percent of a multivalent cation. The water-in-oil emulsion includes an oil phase and an aqueous phase, where the oil phase is a continuous phase containing an inert hydrophobic liquid and the aqueous phase is present as dispersed distinct particles in the oil phase and contains water, the water soluble polymer, and surfactants and an inverting surfactant. The water soluble polymer is made up of 30 to 60 weight percent of a non-ionic monomer, 5 to 50 weight percent of a sulfonic acid containing monomer, and 10 to 60 weight percent of a cationic monomer and makes up from 5 to 40 weight percent of the water-in-oil emulsion.
US11261359B2 Flexible substrates comprising curable compositions containing acetoacetylated resins
This invention relates to an article of manufacture comprising at least one flexible substrate coated with at least one curable composition comprising: I. a first component (I) comprising at least one resin having at least one functional group selected from the group consisting of β-ketoester and malonate functional groups, II. a second component (II) comprising at least one curing agent having at least one aldehyde functional group, and III. a third component (III) comprising at least one compound having amine functionality, salts thereof, or combinations thereof.
US11261358B2 Curable composition
The present invention provides an epoxy resin-based curable composition which may be used as a structural adhesive for an automobile. Particularly, the present invention provides an epoxy resin-based curable composition having excellent low-temperature curability, while maintaining good storage stability and good adhesion.The present invention relates to a curable composition comprising an epoxy resin, a urea-based curing accelerator (A) and an amine-based curing agent (B) having a pyrazine ring.
US11261357B2 Thermally activatable, fast curing adhesive coating
The present invention relates to a thermally activatable adhesive composition for use in a method for producing a stack of metal sheets from glued together sheet metal components, the use of the adhesive composition in a method for producing a stack of metal sheets from glued together sheet metal components, the method for producing a stack of metal sheets from glued together sheet metal components, a sheet metal component coated with the adhesive composition, and a stator or rotor core containing one or more of such sheet metal components.
US11261353B2 Rubber-based adhesive composition and rubber-based adhesive using same
The present invention relates to a rubber-based adhesive composition and a rubber-based adhesive using the same, the composition including: a rubber-based resin; and a rosin-based resin having at least one hydrophilic group.
US11261351B2 Wet and dry surface adhesives
A pressure sensitive adhesive comprising the polymerization product of a polymerizable composition comprising: (a) one or more (meth)acrylate ester monomers; (b) one or more hydrophilic non-acidic monomers; and (c) reactive, ionic surfactant. Also articles comprising such adhesives and methods for making such adhesives and such articles.
US11261349B2 Method for molding a body in a mold
Adhesive tape having a carrier material comprising the following layers: a textile composed of fibers having a softening point greater than or equal to 200° C., and coated with fluoropolymers or silicone polymers, to the top side of which textile a first film composed of fluoropolymers is applied over the whole surface and to the bottom side of which textile a second film is applied over the whole surface, wherein a self-adhesive mass is applied to one side of the carrier material.
US11261348B2 Label construction for ablative laser marking
A label has a topcoat layer and a sacrificial layer. The topcoat layer has a first color having a first L-value and the sacrificial layer has a second color having a second L-value. The topcoat layer comprises at least one reflective pigment and a polymeric binder and the sacrificial layer comprises at least one infrared (IR) absorbing material and a polymeric binder. The first L-value is greater than the second L-value, and the total amount of the at least one reflective pigment is from 40 wt % to 80 wt %, based on the weight of the topcoat layer.
US11261345B2 Hydrolytically stable polymers, method of synthesis thereof and use in bio-electronic devices
A thiol-ene shape memory polymer including a sequential chain of a first type of monomer covalently bonded to a second type of monomer via thiol-ene linkages that form a backbone of the polymer. The first type of monomer includes two or more thiol functional groups and the second type of monomer includes two or more alkene functional groups. The sequential chain of the covalently bonded first and second types of monomers forming the polymer backbone is free of ester groups. Also disclosed in a method of synthesizing the thiol-ene shape memory polymer, a bio-electronic device including a substrate layer composed of the thiol-ene shape memory polymer, and a method of manufacturing the bio-electronic device.
US11261343B2 Coating agent and its use
A coating agent for pencils for writing, sketching or drawing or for cosmetic articles of all kinds, including at least one cellulose fraction, at least one binder, at least one plasticizer, and at least one adhesion promoter, wherein the adhesion promoter is designed as a silane having functional groups.
US11261339B2 Multiamine ligands for nanoparticle solubilization and ink compositions containing nanoparticles capped with the ligands
Ligand-capped scattering nanoparticles, curable ink compositions containing the ligand-capped scattering nanoparticles, and methods of forming films from the ink compositions are provided. Also provided are cured films formed by curing the ink compositions and photonic devices incorporating the films. The ligands bound to the inorganic scattering nanoparticles include a head group and a tail group. The head group includes a polyamine chain and binds the ligands to the nanoparticle surface. The tail group includes a polyalkylene oxide chain.
US11261336B2 Process for applying a metal-organic framework-containing corrosion resistant coating to a substrate
Processes, compositions and agents are included for inhibiting corrosion in various substrates, for example metal substrates. Corrosion inhibitors include organometallic polymers such as metal-organic frameworks (MOFs), including compositions and processes comprising MOFs for inhibiting corrosion in metal substrates. In some aspects, a method of protecting a substrate from corrosion includes applying a protective composition including a corrosion inhibitor to the surface of a substrate, where the corrosion inhibitor includes a metal organic framework (MOF).
US11261333B2 Ceramic colours
Ceramic colours containing effect pigments and a liquid glass forming component for decoration of metallic, ceramic and glassy articles and a process for the preparation of a ceramic glaze.
US11261332B2 Polyhalogenated zinc phthalocyanine, polyhalogenated zinc phthalocyanine pigment, and color filter including pixel portion containing polyhalogenated zinc phthalocyanine pigment
There is provided a polyhalogenated zinc phthalocyanine having good tinting strength and being capable of achieving higher brightness when the polyhalogenated zinc phthalocyanine is used in pixel portions of color filters. The object is achieved by providing the polyhalogenated zinc phthalocyanine represented by general formula 1: (wherein in general formula 1, X1 to X16 are each independently a chlorine atom, a bromine atom, or a hydrogen atom), in which a value obtained by dividing the maximum ion intensity, measured by mass spectrometry, in an m/z range of 1,780 (inclusive) to 1,820 (exclusive) by the maximum ion intensity in the m/z range of 1,820 (inclusive) to 1,860 (inclusive) is 1.00 or less.
US11261331B2 Natural rubber skim block in asphalt compositions and non-asphalt solvent-based coatings
A skim block composition includes a carrier mixed with a skim block addition, the skim block addition including from 0 to less than 100 wt % synthetic polymer, and from greater than 0 to 100% skim block. This provides productive use for the typical waste product skim block, which is the neutralized and coagulated product of skim latex formed during the production of natural rubber latex concentrate by centrifugation.
US11261329B2 Silicone elastomer composition
The present invention provides a tin-free, room temperature curable silicone elastomer composition, wherein the uncured composition is a putty.
US11261328B2 Circuit board using low dielectric resin composition
A circuit board includes an insulating made by a low dielectric resin composition includes a low dielectric resin containing acid anhydride, an epoxy resin, polyphenylene ether resin with vinyl and active esters, maleic acid liquid polybutadiene, and an accelerator. Such low dielectric resin can be dissolved in organic solvent more easily than a low dielectric resin without acid anhydride, and the low dielectric resin containing acid anhydride has a better compatibility with other organic components than a low dielectric resin without acid anhydride. A low dielectric resin composition with lower dielectric constant and better properties can thus be obtained.
US11261326B2 Polyamide resin composition for extrusion molded products exposed to high-pressure hydrogen, and extrusion molded product
A polyamide resin composition for an extrusion-molded article exposed to high-pressure hydrogen gas contains: 70 to 99 parts by weight of a polyamide 6 resin (A); 1 to 30 parts by weight of an impact modifier (B); and 0.005 to 1 parts by weight of a metal halide (C) with respect to a total of 100 parts by weight of the polyamide 6 resin (A) and the impact modifier (B). The polyamide resin composition has a melt tension of 20 mN or more when measured at 260° C. and a take-up speed at strand break of 30 m/min or more when measured at 260° C.
US11261324B2 Resin composition including a polycarbonate resin and a fluorine-containing polymer, and molded article
A resin composition containing a polycarbonate resin and a fluorine-containing copolymer. The fluorine-containing copolymer is a copolymer containing a polymerized unit based on tetrafluoroethylene in an amount of 75% by mass or more of all polymerized units and at least one selected from a polymerized unit based on hexafluoropropylene and a polymerized unit based on a perfluoro(alkyl vinyl ether) in an amount of 2% by mass or more. Also disclosed is a molded article formed from the resin composition, the polycarbonate resin constituting a continuous phase and the fluorine-containing copolymer constituting a dispersed phase having an average particle size of 0.01 to 2.5 μm.
US11261323B2 Conformable thermoplastic compositions and articles
A conformable polymeric composition containing a polymeric material melt-blending from a composition containing (a) from about 50 to about 80 wt. % of at least one polyester thermoplastic polymer which is amorphous or becomes amorphous when melted, and (b) from about 20 to about 50 wt. % of at least one elastomeric polymer which has a flexural modulus of less than 700 MPa and a glass transition temperature less than 25° C., based on the combined weight of (a) and (b), wherein the composition is characterized by: a dead fold angle equal to or less than about 20°.
US11261320B2 Injection molded article and shoe
In order to provide an injection molded article that is able to be easily produced so that a molding surface of a forming mold is accurately reflected on the injection molded article, and, in order to provide a shoe having a shoe part excellent in appearance, the shoe part is formed of an elastomer composition showing a certain heat melting characteristics.
US11261316B2 Plastic living hinges with block composite polymer
The present disclosure provides a plastic living hinge. The plastic living hinge includes a blend containing (A) an ethylene-based polymer; and (B) a composite component selected from the group consisting of a block composite, a crystalline block composite, and a combination thereof.
US11261314B2 Pneumatic tire
A pneumatic tire comprising a tread composed of a rubber composition containing 30 to 120 parts by mass of silica having a BET specific surface area of 180 to 280 m2/g based on 100 parts by mass of a rubber component, wherein, under a normal state with no load where the pneumatic tire is mounted with a normal rim and filled with a normal internal pressure, a grounding surface shape in which a normal load is applied and the tread is pressed against a plane surface satisfies the following equation (1): 0.95≤SL0/SL80≤1.6 (wherein, SL0 is a ground contact length in a circumferential direction of the tire on a tire equator, and SL80 is a ground contact length in a circumferential direction of the tire on a position away from the tire equator by a distance in a tire axial direction of 80% of a tread grounding half width.)
US11261313B2 Rubber composition for tire tread and pneumatic tire
A rubber composition for a tire tread according to an embodiment includes a rubber component containing a natural rubber, a styrene-butadiene rubber, and a polybutadiene rubber; oil-absorbent polymer particles having a glass transition temperature of −70 to −20° C., formed from a polymer whose molecular weight distribution is less than 3.0, and having an oil absorption of 100 to 1,500 ml/100 g; an oil; and silica. The content of the oil-absorbent polymer particles is 0.5 to 25 parts by mass per 100 parts by mass of the rubber component. As a result, snow performance and wet performance can be improved.
US11261312B2 Rubber blend, sulfur-crosslinkable rubber mixture, and vehicle tire
The invention relates to a sulfur-crosslinkable rubber mixture comprising a rubber blend composed of at least one solution-polymerized diene polymer A of high molecular weight and at least one solution-polymerized polymer B of low molecular weight, wherein at least one of polymers A and B has been functionalized at the chain end and/or along the polymer chain and/or at a coupling site with at least one group selected from epoxy groups, hydroxyl groups, carboxyl groups, silane sulfide groups, amino groups, siloxane groups, organosilicon groups, phthalocyanine groups and amino group-containing alkoxysilyl groups, 30 to 300 phr of at least one silica and 1 to 20 phf of at least one substance of formula I) as silane coupling agent (R1R2R3)Si—S4—Si(R3R2R1)  II) where R1, R2, R3 in the structure may be the same or different and may be selected from linear or branched alkoxy, cycloalkoxy, alkyl, cycloalkyl or aryl groups having 1 to 20 carbon atoms.
US11261304B2 Polyimide film forming composition and polyimide film produced by using same
The present invention provides a polyimide film forming composition which comprises a polyamic acid or a polyimide in an oligomer form or in a low-molecular weight form, the polyamic acid or the polyimide being prepared from a diamine containing an intramolecular imide group, and thus can provide a polyimide film having improved heat resistance while retaining optical properties thereof. In addition, the polyimide film according to the present invention can reduce not only a laser energy density (E/D) required in the laser exfoliation process but also remarkably decrease an amount of ash generated by an exfoliation process, thereby further improving the reliability of a device in a display manufacturing process.
US11261300B2 Methods and systems for generating aqueous polymer solutions
Provided herein are liquid polymer (LP) compositions comprising a synthetic (co)polymer (e.g., an acrylamide (co)polymer), as well as methods for preparing aqueous polymer solutions by combining these LP compositions with an aqueous fluid. The resulting aqueous polymer solutions can have a concentration of a synthetic (co)polymer (e.g., an acrylamide (co)polymer) of from 50 to 15,000 ppm, and a filter ratio of 1.5 or less at 15 psi using a 1.2 μm filter. Also provided are methods of using these aqueous polymer solutions in oil and gas operations, including enhanced oil recovery.
US11261298B2 Tailored SiOC-based polyethersiloxanes
SiOC-based polyethersiloxanes are prepared based on linear α,ω-hydroxy group-bearing siloxanes. In a first step, α,ω-acetoxy group-bearing linear polysiloxanes are prepared. In a second step, the α,ω-acetoxy group-bearing linear polysiloxanes are converted into the desired organosiloxane units, preferably shorter organosiloxane units, wherein the thus converted organosiloxane units have α,ω-acetoxy groups. In a third step, the α,ω-acetoxy group-bearing linear polysiloxanes from step 2 react with polyetherols to give SiOC-based polyethersiloxanes.
US11261294B2 Thermoplastic resin and optical member
The purpose of the present invention is to provide a thermoplastic resin that has a high refractive index and enables low birefringence and balanced heat resistance and moldability. This thermosetting resin includes repeating units represented by formula (1). (In the formula, the rings Z are the same or different and represent an aromatic hydrocarbon ring, R1 and R2 independently represent a C1-C12 hydrocarbon group optionally including a hydrogen atom, a halogen atom, and an aromatic group, Ar1 and Ar2 represent a C6-C10 aromatic group optionally having a substituent, L1 and L2 independently represent a divalent linking group, j and k independently represent an integer of 0 or more, m and n independently represent 0 or 1, and W is at least one selected from the groups represented by formulae (2) and (3).) (In the formula, X represents a divalent linking group.)
US11261291B2 Materials for electronic devices
The present application relates to a polymer containing at least one structural unit of a formula (I) and at least one further structural unit selected from structural units A, B and C. The present application further relates to the use of the polymer in an electronic device and to a process for preparing the polymer. The present application further relates to an electronic device comprising the polymer.
US11261285B2 Stretchable film and method for forming stretchable film
A stretchable film includes, in a stacked form: a polyurethane film containing a repeating unit having a fluorine atom; and a polyurethane film containing a repeating unit having a silicon atom. At least one surface of the stretchable film is made of the polyurethane film containing a repeating unit having a fluorine atom. Thus, provided are: a stretchable film having excellent stretchability and strength, with the film surface having excellent water repellency; and a method for forming the stretchable film.
US11261284B2 Process for the preparation of a thixotropic composition
The invention relates to a process for the preparation of a thixotropic composition comprising polyurea particles, said process comprising contacting and reacting in a liquid medium reactants to form a polyurea and precipitating the polyurea to form polyurea particles, wherein acoustic vibration is applied during contacting of the reactants or as a post-treatment on the formed polyurea particles or both. The invention further relates to a thixotropic composition obtainable by the process, in particular thixotropic composition comprising high amounts of polyurea particles and optionally a polymer resin having high thixotropic efficiency. The compositions can be used, in particular as a masterbatch, in preparation of i.a. coating compositions.
US11261280B2 Fluorinated block copolymers
Described herein is a millable fluorinated block copolymer having (a) at least one A block, wherein the A block is a semi-crystalline segment comprising repeating divalent monomeric units derived from at least TFE, HFP and VDF; (b) at least one B block, wherein the B block is a segment comprising repeating divalent monomeric units derived from at least HFP and VDF; and (c) a bisolefin monomer, wherein at least (i) the semi-crystalline segment of the A block comprises repeating divalent monomeric units derived from TFE, HFP, VDF, and the bisolefin monomer, (ii) the segment of the B block comprises repeating divalent monomeric units derived from HFP, VDF, and the bisolefin monomer, or (iii) a combination thereof; and wherein the millable fluorinated block copolymer has a modulus of 0.1 to 2.5 MPa at 100° C.
US11261279B2 Actinic radiation curable polymeric mixtures, cured polymeric mixtures and related processes
The present disclosure is directed to actinic radiation curable polymeric mixtures, cured polymeric mixtures, tires and tire components made from the foregoing, and related processes.
US11261275B2 Protein stabilizer and protein stabilization reagent
There is provided a protein stabilizer for stably storing a protein in a solution. The protein may be an enzyme, an antibody, an enzyme-labeled antibody, or the like for a biochemical assay, etc. There is further provided a protein stabilization reagent comprising a protein-containing solution and the protein stabilizer dissolved therein. The protein stabilizer comprises a copolymer prepared by copolymerizing a monomer (a) of the following formula (1), a monomer (b) of the following formula (2), and a monomer (c) of the following formula (3).
US11261273B2 Resin, resist composition and method for producing resist pattern
Disclosed is a resin comprising a structural unit derived from a compound represented by formula (I′) and a structural unit having an acid-labile group: wherein R1 and R2 each independently represent an alkyl group which may have a halogen atom, a hydrogen atom or a halogen atom, Ar represents an aromatic hydrocarbon group which may have a substituent, L1 represents a group represented by formula (X1-1), etc., L11, L13, L15 and L17 each independently represent an alkanediyl group, L12, L14, L16 and L18 each independently represent —O—, —CO—, —CO—O—, —O—CO— or —O—CO—O—, and * and ** are bonds, and ** represents a bond to an iodine atom.
US11261270B2 Polyvinyl alcohol and method for producing polyvinyl alcohol
A polyvinyl alcohol has a number-average molecular weight (Mn) from 4,400 to 440,000, a molecular weight distribution (Mw/Mn) from 1.05 to 1.70, a degree of saponification from 80 to 99.99 mol %, wherein the polyvinyl alcohol contains an end group represented by a formula (I) below, and a molar ratio (X) of the end group based on total monomer units and the number-average molecular weight (Mn) satisfy a formula (1) below. Such a polyvinyl alcohol has a narrow molecular weight distribution and a high number-average molecular weight with hue good. (In the formula, R1 denotes an optionally substituted aromatic group having a carbon number from 6 to 20, and R2 denotes a hydrogen atom, an alkyl group having a carbon number from 1 to 20, or an optionally substituted aromatic group having a carbon number from 6 to 20.) X·Mn/44≥0.5  (1)
US11261262B2 Readily isolated bispecific binding molecules with native format having mutated constant regions
The invention provides heterodimer bispecific antigen-binding molecules that include a first polypeptide that does not include an IgG CH1 domain and a second polypeptide where there is at least one mutation in the IgG CH3 domain that abolishes the ability of the second polypeptide to bind CH3-specific affinity media such that the first and second polypeptides have different affinities with respect to CH1 and CH3 specific affinity reagents that allows rapid isolation by differential binding. The invention also provides bispecific antibodies that have CH1 and CH3 regions with different affinities with respect to affinity reagents that allows rapid isolation by differential binding. The invention also concerns bispecific antibodies which are heterodimers of two IgG heavy chains that differ by at least two amino acids that allow for rapid isolation based on a differential affinity of one mutated heavy chain and a second mutated heavy chain toward two different affinity reagents.
US11261256B2 Methods for depleting or inhibiting the migration of regulatory T-cells in early or late stages of cancer
The present disclosure provides methods of modulating regulatory T-cell activity and function.
US11261254B1 Antibodies
The present invention relates to antibodies binding to B7H4, including bispecific antibodies binding to B7H4 and CD3. The invention further provides pharmaceutical compositions comprising the antibodies and use of the antibodies for therapeutic and diagnostic procedures, in particular in cancer therapy.
US11261247B2 Modulators
Antibodies that modulate insulin receptor signaling are provided.
US11261245B2 Ultra-potent neutralization of GM-CSF by multispecific antibodies and uses thereof
The present invention provides multispecific antibodies, and antigen binding fragments thereof, that potently neutralize a cytokine and that may thus be useful in the prevention and/or treatment of inflammatory and/or autoimmune diseases. In particular, the present invention provides a multispecific antibody, or an antigen binding fragment thereof, comprising at least two different domains specifically binding to at least two different, non-overlapping sites in a cytokine and an Fc moiety. The invention also relates to nucleic acids that encode such antibodies and antibody fragments and immortalized B cells and cultured plasma cells that produce such antibodies and antibody fragments. In addition, the invention relates to the use of the antibodies and antibody fragments of the invention in screening methods as well as in the diagnosis, prophylaxis and treatment of inflammatory and/or autoimmune diseases.
US11261244B2 Antibody against human TGF-β LAP degradate, and use thereof
Disclosed is an isolated monoclonal antibody against a human Transforming Growth Factor-β (TGF-β) Latency Associated Protein (LAP) degradate, the isolated monoclonal antibody being capable of recognizing an integrin binding site in the human TGF-β LAP degradate.
US11261236B2 Fusion peptide comprising thrombus-targeting peptide, ferritin fragment and thrombolytic peptide, and use thereof
The present invention relates to: a fusion peptide comprising a thrombus-targeting peptide, ferritin fragment and a thrombolytic peptide; and a use thereof and, more specifically, to: a fusion peptide in which a thrombus-targeting peptide, ferritin fragment and a thrombolytic peptide are sequentially linked; a composition for preventing or treating thrombotic disorders, containing the same as an active ingredient; a method for treating thrombotic disorders; and a therapeutic use. According to the present invention, CLT-sFt-μPn DCNC as a novel plasmin-based thrombolytic nanocage has: an effect of targeting a site at which thrombus is present; a low sensitivity to inhibitors present in the circulatory system; pharmacological activity strongly destroying both arterial and venous thrombi; and no side effects of bleeding, and thus can be very useful in developing an agent for preventing or treating thrombotic disorders.
US11261235B2 Method for promoting wound healing
The present invention discloses a method for treating wounds and for accelerating the healing of wounds by administering an effective amount of a pharmaceutical composition containing type VII collagen protein, mini-C7 protein, variants thereof or any combinations thereof. The pharmaceutical composition may be administered through a variety of routes including intravenous injection, topical application, or oral ingestion. The method may further include administering a genetically modified fibroblast capable of expressing type VII collagen protein, miniC7 protein, variants thereof or small growth factors to achieve synergistic healing effect.
US11261230B2 Synthetic somatostatin receptor ligands
Disclosed are Somatostatin receptor ligands comprising a peptide moiety, pharmaceutical compositions and uses thereof. Disclosed are also synthetic Somatostatin receptor ligands comprising a cyclic peptide moiety and an active agent moiety covalently bonded to the cyclic peptide moiety through a nitrogen atom of a side chain functional group of an internal residue of the cyclic peptide moiety, pharmaceutical compositions and uses thereof. Disclosed are also synthetic Somatostatin receptor ligands comprising a cyclic peptide moiety and a nanoparticle active agent moiety covalently bonded to the cyclic peptide moiety, pharmaceutical compositions and uses thereof.
US11261229B2 Ultra-long acting insulin-Fc fusion proteins and methods of use
The present disclosure provides recombinantly manufactured ultra-long acting insulin-Fc fusion proteins for use in treating canine and feline diabetes. The insulin-Fc fusion proteins comprise an insulin polypeptide linked via a peptide linker to an Fc-fragment of canine or feline origin. Based on the results obtained, creating a treatment that is amenable to low cost manufacturing, exhibits sufficient in vivo bioactivity, displays extended duration of bioactivity, does not induce anti-drug antibodies, and substantially retains is potency over multiple administrations, requires a non-obvious combination of insulin polypeptide, peptide linkers, and species-specific Fc fragment, in addition to selective mutations on one or more of these components. Exemplary ultra-long acting insulin-Fc fusion proteins, polynucleotides encoding these insulin-Fc fusion proteins, and pharmaceutical formulations of exemplary insulin-Fc fusion proteins are provided, in addition to methods of use and preparation.
US11261227B2 Glucagon derivative and a composition comprising a long acting conjugate of the same
A glucagon derivative, a long-acting conjugate of the glucagon derivative, and a use thereof are disclosed.
US11261224B2 Peptides and combination of peptides for use in immunotherapy against lung cancer, including NSCLC, SCLC and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US11261223B2 Methods of treating cancers with CT45 targeted therapies
The current disclosure relates to methods for treating ovarian cancer based on specific antigen expression of the cancer. Furthermore, the expressed antigen may be used in immunotherapeutic methods for treatment of the ovarian cancer. Aspects of the disclosure relate to immunotherapies targeting CT45 polypeptides, methods for treating ovarian cancer based on CT45 expression, and kits for detecting CT45 polypeptides and nucleotides.
US11261222B2 Transdermal peptide with nuclear localization ability and use thereof
A transdermal peptide with a nuclear localization ability and having an amino acid sequence as shown in SEQ ID NO: 1 is disclosed. A fusion protein including a macromolecular protein with one end being linked to the transdermal peptide is also disclosed. The transdermal peptide can be used in the preparation of a medicament or a transdermal preparation for treating skin diseases. A medicament for treating a skin disease includes the transdermal peptide and a pharmaceutically acceptable excipient. The transdermal peptide enters the cells autonomously to locate in the nuclei, and can penetrate through the stratum corneum of the skin into cells in the dermis. The peptide is conveniently synthesized artificially and suitable for transdermal administration, and has a therapeutic potential via transdermal administration by carrying a drug for treating skin diseases.
US11261218B2 Species of genus Pseudomonas
The present invention relates to a species of genus Pseudomonas identified as Pseudomonas BR11571, termed Candidatus Pseudomonas metallosolvens, having Accession Deposit Number DSM 32538.
US11261217B2 Expression of Klebsiella oxytoca polypeptides involved in lysine decarboxylation, and methods and applications thereof
One aspect provided herein relates to lysine decarboxylase polypeptides comprising mutants of SEQ ID NO: 2 (i.e., mutants of Klebsiella oxytoca (K. oxytoca) Ldc) and/or fragments thereof. In certain embodiments, the mutants or fragments thereof may have at least about 95% sequence identity with SEQ ID NO: 2. Another aspect provided herein relates to a DNA polynucleotide comprising one or more lysine decarboxylase nucleotide sequences of mutants of SEQ ID NO: 1 (i.e., mutants of K. oxytoca ldc), fragments thereof, or fragments of SEQ ID NO: 1 (i.e., fragments of K. oxytoca ldc). In certain embodiments, the DNA polynucleotide as disclosed herein may encode one or more lysine decarboxylase polypeptides provided herein. In certain embodiments, the DNA polynucleotide as disclosed herein may encode SEQ ID NO: 2, mutants, and/or fragments thereof. In certain embodiments, the lysine decarboxylase nucleotide sequences provided herein may have at least 95% sequence identity with SEQ ID NO: 1 or SEQ ID NO: 3. Another aspect provided herein relates to expression vectors comprising the DNA polynucleotides described herein used for production of a lysine-derived product. Other aspects provided herein include transformants, mutant host cells, methods for the production of lysine decarboxylases, and methods for the production of a lysine-derived product.
US11261216B2 Engineered hepatitis B core polypeptide
Genetically modified HBc polypeptides are provided.
US11261215B2 Somatostatin prodrugs
The present invention provides prodrugs of somatostatin peptide and peptide analogs that are tissue permeable and oral bioavailable and enable activity of the somatostatin analog at the circulation or target tissue after cleavage of charge-masking lipophilic moieties. Pharmaceutical compositions comprising these prodrugs and their use in therapy and diagnosis are also provided.
US11261211B2 19-NOR neuroactive steroids and methods of use thereof
Provided herein are 3,3-disubstituted 19-nor-steroidal compounds according to Formula (1): and pharmaceutical compositions thereof. Such compounds are contemplated useful for the prevention and treatment of a variety of CNS-related conditions, for example, treatment of sleep disorders, mood disorders, schizophrenia spectrum disorders, disorders of memory and/or cognition, movement disorders, personality disorders, autism spectrum disorders, pain, traumatic brain injury, vascular diseases, substance abuse disorders and/or withdrawal syndromes, tinnitus, and status epilepticus.
US11261210B2 Glycosylated antitumor ether lipids as novel cancer stem cell cytotoxic agents
Glycosylated antitumor ether lipids (GAELs) are effective cytotoxic agents against cancer stem cells. Furthermore, combining GAELs which kill cells by a caspase-independent pathway with agents that kill cells by apoptosis will lead to elimination of the differentiated tumor cells and the undifferentiated cancer stem cells leading to an elimination of the tumor and preventing recurrence.
US11261208B2 Compounds for use as iron(III) MRI contrast agents
Provided are macrocyclic compounds and compounds with two or more macrocyclic groups, iron coordinated macrocyclic compounds, and iron coordinated compounds with two or more macrocyclic groups. The iron is high-spin iron(III). The iron coordinated compounds may exhibit a negative redox potential (e.g., relative to a normal hydrogen electrode at a biologically relevant pH, for example, a pH of 6.5-7.5). The compounds can be used as MRI contrast agents.
US11261205B2 Oxazolidinone-quinolone hybrid antibacterial for the parenteral treatment of prophylaxis of bacterial diseases
The present invention relates to the use of oxazolidinone-quinolone hybrids for the parenteral (especially intravenous) treatment or prophylaxis of bacterial diseases. The present invention relates moreover to improved methods of administering oxazolidinone-quinolone hybrid antibacterials.
US11261202B2 Catalytic reduction of halogenated carbosilanes and halogenated carbodisilanes
Selective reduction methods for halogenated carbosilanes and carbodisilanes are disclosed. More particularly, high yields of the desired carbosilanes and carbodisilanes are obtained by reduction of their halogenated counterparts using a reducing agent and tetrabutylphosphonium chloride (TBPC) as a catalyst.
US11261200B2 Heteroaryltrifluoroborate compounds for the treatment of mycobacterial infections
Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.
US11261191B2 Imidazotriaines and imidazopyrimidines as kinase inhibitors
The present invention is directed to imidazo[1,2-b][1,2,4]triazines and imidazo[1,2-a]pyrimidines, and pharmaceutical compositions thereof, which are inhibitors of kinases such as c-Met and are useful in the treatment of cancer and other diseases related to the dysregulation of kinase pathways.
US11261189B2 Substituted 2,4 diamino-quinoline as new medicament for fibrosis, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases
2-primary amino-4-secondary amino-quinoline derivatives, their manufacture, pharmaceutical compositions comprising them and their use as medicaments are disclosed. The compounds are useful as a medicament in treating and/or decreasing the severity and/or progression and/or preventing fibrosis and/or related diseases, or for use as a medicament in treating, decreasing the severity and/or progression of and/or preventing autophagy and/or related diseases, for inhibiting autophagy flux, and for inhibiting cathepsins B (CTSB), L (CTSL) and/or D (CTSD) and/or related diseases.
US11261184B2 [1,6]naphthyridine compounds and derivatives as CDK8/CDK19 inhibitors
The present invention encompasses compounds of formula (I) wherein the groups R1 to R5, A and q have the meanings given in the claims and specification, their use as inhibitors of CDK8/19, pharmaceutical compositions which contain compounds of this kind and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.
US11261174B2 Pyrazole O-linked carbamoyl cyclohexyl acids as LPA antagonists
The present invention provides compounds of Formula (I) or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein all the variables are as defined herein. These compounds are selective LPA receptor inhibitors.
US11261173B2 Bradykinin B2 receptor antagonists
The invention relates to a compound according to general formula (I), which acts as a bradykinin (BK) B2 receptor antagonist; to a pharmaceutical composition containing one or more of the compound(s) of the invention; to a combination preparation containing at least one compound of the invention and at least one further active pharmaceutical ingredient; and to uses of said compound(s), including the use as a medicament.
US11261172B2 Squarylium compounds and infrared cut films, infrared cut filters and electronic devices including the same
A squarylium compound has high transmittance in a visible wavelength spectrum of light and is configured to selectively absorb light in an infrared/near infrared wavelength spectrum of light.
US11261171B1 Isoindolinone inhibitors of the MDM2-P53 interaction having anticancer activity
The invention provides a compound of formula (I): or tautomer or a solvate or a pharmaceutically acceptable salt thereof, wherein the various substituents are as defined in the claims. Also provided are pharmaceutical compositions containing the compounds of formula (I), processes for making the compounds and the medical uses of the compounds.
US11261170B2 Aromatic compound, pharmaceutical composition and use thereof
The invention relates to an aromatic compound, pharmaceutical composition comprising the same, and a method for preparing the compound and an intermediate thereof. The invention also relates to use of the compound for the manufacture of a medicament for the prevention or treatment of a PPAR-related disease.
US11261168B2 Process for synthesizing 5-hydroxymethylfurfural
The invention relates to a process for synthesizing 5-hydroxymethylfurfural from a fructose-containing feedstock in the presence of at least one aprotic polar solvent and at least one dehydration catalyst, in which process the maximum instantaneous fructose concentration 5.0 wt %.
US11261166B2 Lipophilic macrocyclic ligands, complexes thereof, and uses of same
The present invention relates to novel lipophilic macrocyclic ligands, the complexes thereof, in particular radioactive complexes, and the uses of same in medical imaging and/or in therapy, in particular in interventional radiology.
US11261158B2 Synthesis of 2-indolinone derivatives
The present disclosure relates to a preparation method of methyl (E)-1-acetyl-3-(methoxy(phenyl)methylene)-2-oxoindoline-6-carboxylate from methyl 2-oxoindoline-6-carboxylate using high reaction temperatures and a reaction solvent enabling azeotropic removal of acetic acid during the reaction.
US11261151B2 Methods for making and using endoxifen
The present disclosure provides industrially scalable methods of making (Z)-endoxifen or a salt thereof, crystalline forms of endoxifen, and compositions comprising them. The present disclosure also provides methods for treating hormone-dependent breast and hormone-dependent reproductive tract disorders.
US11261150B2 Method for purifying (meth)acrylic esters
The invention relates to the production of (meth)acrylic esters according to a continuous process by transesterification, and in particular to the purification of a crude reaction mixture comprising a C4-C12 (meth)acrylic ester using a divided wall column employed in a particular configuration. This configuration results in a simplification of the purification process with a reduced energy consumption and a minimized content of impurities present in the purified (meth)acrylic ester. The invention also relates to a process for the production of C4-C12 (meth)acrylic ester comprising this recovery/purification process.
US11261148B2 Method for producing carbonyl compound
A method for producing a carbonyl compound represented by formula (1): wherein R1 is hydrogen or an organic group; R2 is hydrogen or an organic group; and R3 is hydrogen or an organic group; or two or three of R1, R2, and R3 may be linked to form a ring that may have at least one substituent, the method comprising step A of oxidizing an olefin compound represented by formula (2): wherein symbols are as defined above, by an oxidizing agent in the presence of (a) a non-alcohol organic solvent, (b) water, (c) a metal catalyst, and (d) an additive represented by the formula: MXn, wherein M is an element belonging to any one of Group 1, Group 2, Group 13, Group 14, and Group 15 in the periodic table, or NR4, wherein R is hydrogen or a C1-10 organic group; X is halogen; and n is a number of 1 to 5.
US11261147B2 Process for preparing fluorobenzene and benzoic acid hypofluorite
The invention relates to a use of a fluorination gas, the elemental fluorine (F2) is preferably present in a high concentration, e.g. in a concentration of elemental fluorine (F2), especially of equal to much higher than 15% or even 20% by volume (i.e., at least 15% or even 20% by volume), and to a process for the manufacture of a fluorinated benzene starting from benzoic acid by direct fluorination employing a fluorination gas. The elemental fluorine (F2) is preferably present in high concentration, and subsequent decarboxylation of the benzoic acid hypofluorite obtained by direct fluorination. The process of the invention is also directed to the manufacture of benzoic acid hypofluorite by direct fluorination of benzoic acid. Especially the invention is of interest in the preparation of fluorinatedbenzene, final products and as well intermediates, for usage in agro-, pharma-, electronics-, catalyst, solvent and other functional chemical applications.
US11261146B2 Preparation of 2,3,3,3-tetrafluoropropene and intermediates thereof
The present invention provides a process for preparation of 2,3,3,3-tetrafluoropropene and intermediates thereof. Owing to its low global warming potential and zero ozone depleting potential, it is been proposed as a replacement for existing chlorofluorocarbons and hydrofluorocarbons as refrigerant.
US11261145B2 Process for preparing bromotrichloromethane
The present invention relates to a process for preparing bromotrichloromethane comprising a) providing bromine in chloroform; and b) radiation of the resulting solution with light in the range of 350 to 550 nm, wherein said solution of bromine in chloroform is not radiated with radiation of a wavelength below 350 nm.
US11261143B2 Apparatus and process for separating gases from catalyst
In an FCC apparatus in which swirl arms are used to discharge gas and catalyst from a riser, the swirling movement of the catalyst particles is inhibited while impeding the catalyst particles and gaseous products from exiting the disengaging chamber and entering a reactor annulus. The catalyst particles and gaseous products pass through a tunnel comprising a vertical wall to enter the reactor annulus. The vertical wall presents a face that is opposed to the angular direction in which the catalyst particles and gaseous products swirl.A baffle may be located at the intersection between the reactor annulus and the disengaging chamber to deflect catalyst laterally in a stripping section after exiting the reactor annulus. The baffle may be equipped with openings to fluidize the large proportion of catalyst passing over this region to effectively pre-strip this catalyst before it enters a stripping section.
US11261140B2 Processes and systems for the conversion of acyclic hydrocarbons to cyclopentadiene
This invention relates to processes and systems for converting acyclic hydrocarbons to alkenes, cyclic hydrocarbons and/or aromatics, for example converting acyclic C5 hydrocarbons to cyclopentadiene in a reactor system. The process includes heating an electrically-conductive reaction zone by applying an electrical current to the first electrically-conductive reaction zone; and contacting a feedstock comprising acyclic hydrocarbons with a catalyst material in the electrically-conductive reaction zone under reaction conditions to convert at least a portion of the acyclic hydrocarbons to an effluent comprising alkenes, cyclic hydrocarbons, and/or aromatics.
US11261136B2 Triarylmethane compounds for controlling enzyme-induced urea decomposition
Provided herein are compositions and methods for controlling enzyme-induced urea decomposition attendant to the application of solid or liquid urea-containing fertilizers to soils. More particularly, the subject matter disclosed herein is concerned with selected triarylmethane compounds as urease inhibitors and their use, either alone or in combination with tetrapolymer synergists. Further, the disclosed compositions have good storage stability, long-lived activity in soil, and avoid the toxicity issues common with present-day urease inhibitors used in agriculture.
US11261134B2 Honeycomb formed body and method for producing honeycomb structure
A honeycomb formed body containing a ceramics raw material, the honeycomb formed body including: a pillar shaped honeycomb structure portion having a plurality of rectangular cells, the cells being defined by partition walls and extending from a first end face to a second end face to form flow paths; an outer peripheral portion having outer peripheral portions X where the partition walls are covered with an outer peripheral wall; and outer peripheral portions Y where the partition walls are exposed. Each of the outer peripheral portions X includes a tapered portion having a gradually deceasing thickness of the outer peripheral wall toward a boundary portion with an adjacent outer peripheral portion Y. The tapered portion requires a length equal to or more than one time of an average cell pitch in the outer peripheral direction until thickness of the outer peripheral wall is halved.
US11261132B2 Ceramic raw material powder, multilayer ceramic capacitor and manufacturing method of multilayer ceramic capacitor
Ceramic raw material powder includes: a main phase having a perovskite structure, wherein elements acting as a donor and an acceptor are solid-solved in B sites of the perovskite structure, wherein a relationship of (concentration of the element acting as a donor)×(valence of the element acting as a donor−4)<(concentration of the element acting as an acceptor)×(4−valence of the element acting as an acceptor) is satisfied, in a center region of each grain of the ceramic raw material powder, wherein a relationship of (concentration of the element acting as a donor)×(valence of the element acting as a donor−4)>(concentration of the element acting as an acceptor)×(4−valence of the element acting as an acceptor) is satisfied, in a circumference region of each grain of the ceramic raw material powder.
US11261128B2 Low-reflection coating glass
The present invention provides low-reflection coating glass in which a dielectric layer having a higher refractive index and a dielectric layer having a lower refractive index are stacked alternately on a glass substrate.
US11261127B2 Production method for sheets of glass with a diffuse finish, and resulting sheet of glass
The present invention relates to a process for manufacturing glass sheets with diffuse finish and the resulting glass sheet by this process. The glass sheet is subjected to a series of alternate immersions in acidic solutions and alkaline solutions to remove impurities and waste and to generate a diffuse finish on both sides of the glass sheet. The process generates in the glass sheet in at least one side, a diffuse surface with a peak to valley roughness (Rt) of between 5.8343 μm and 9.3790 μm; an average roughness (Ra) value between 0.8020 μm and 0.9538 μm; an RMS roughness between 0.9653 μm and 1.1917 μm; a solar transmission between 84.8% and 46.50%;a solar reflection between 7.4 and 4.4%; a light transmission between 88.5% and 67.70%; a reflection of light between 6.50% and 5.20%; and UV transmission between 35.60% and 70.20%.
US11261123B2 Glass
Devised is a glass which has high heat resistance and a low thermal expansion coefficient, and is excellent in productivity. A glass of the present invention includes as a glass composition, in terms of mol %, 55% to 80% of SiO2, 12% to 30% of Al2O3, 0% to 3% of B2O3, 0% to 1% of Li2O+Na2O+K2O, and 5% to 35% of MgO+CaO+SrO+BaO, and has a thermal expansion coefficient within a temperature range of from 30° C. to 380° C. of less than 40×10−7/° C.
US11261121B2 Optical fiber preforms with halogen doping
Preparation of halogen-doped silica is described. The preparation includes doping silica with high halogen concentration, sintering halogen-doped silica to a closed-pore state, and subjecting the closed-pore silica body to a thermal treatment process and/or a pressure treatment process. The temperature of thermal treatment is sufficiently high to facilitate reaction of unreacted doping precursor trapped in voids or interstices of the glass structure, but is below temperatures conducive to foaming. Core canes or fibers drawn from halogen-doped silica subjected to the thermal treatment and/or pressure treatment show improved optical quality and possess fewer defects. The thermal treatment and/or pressure treatment is particularly advantageous when used for silica doped with high concentrations of halogen.
US11261119B2 Cold-formability of glass laminate article utilizing stress prediction analysis and related methods
Articles and methods related to the cold-forming of glass laminate articles utilizing stress prediction analysis are provided. A cold-forming estimator (CFE) value that is related to the stress experienced by a glass sheet of a glass laminate during cold-forming is calculated based on a plurality of geometric parameters of glass layer(s) of a glass laminate article. The calculated CFE value is compared to a cold-forming threshold related to the probability that defects are formed in the complexly curved glass laminate article during cold-forming. Cold-formed glass laminate articles are also provided having geometric parameters such that the CFE value is below the cold-forming threshold.
US11261118B2 Apparatus and method for rapid cooling of a glass ribbon in a glass making process
An apparatus for making a glass sheet including a forming apparatus, a transition member, and a heat transfer device. The forming apparatus forms a glass ribbon from a supply of molten glass. The transition member encloses the glass ribbon adjacent the forming apparatus, and defines an interior space through which the glass ribbon passes. The heat transfer device is disposed within the interior space, and comprises a tube and a fin. The tube defines an exterior surface and an interior passage. The fin projects from the exterior surface. With this construction, the heat transfer device functions to extract heat radiated by the glass ribbon while minimizing the formation of flow vortices.
US11261117B2 System and method for synchronized oxy-fuel boosting of a regenerative glass melting furnace
A system and method for synchronized oxy-fuel boosting of a regenerative glass melting furnace including first and second sets of regenerative air-fuel burners, a first double-staged oxy-fuel burner mounted in a first wall, and a second double-staged oxy-fuel burner mounted in a second wall, each oxy-fuel burner having a primary oxygen valve to apportion a flow of oxygen between primary oxygen and staged oxygen and a staging mode valve to apportion the flow of staged oxygen between an upper staging port and a lower staging port in the respective burner, and a controller programmed to control the primary oxygen valve and the staging mode valve of each of the first and second oxy-fuel burners to adjust flame characteristics of the first and second oxy-fuel burners depending on the state of operation of the furnace.
US11261114B2 Aerobic treatment system
An aerobic treatment system is disclosed herein in which an aerobic holding treatment tank, having an inlet adapted to receive wastewater and an outlet adapted to discharge treated wastewater therefrom, is in communication with an aeration pump having an inlet nozzle in communication with the aerobic holding treatment tank for providing a source of air to the contents of the aerobic holding treatment tank. The aerobic treatment system may further include a generation pump disposed below ground level and in fluid communication with the aerobic holding treatment tank. The generation pump is provided in fluid communication with a high pressure pump in fluid access with an evaporator fan and misting nozzle. The system may further include electronics to connect to grid power, backup electronics for connection to auxiliary power sources, and at least one solar collector for providing a source of electricity.
US11261110B2 Systems and methods for controlling evaporative fluid loss
A system for reducing evaporative cooling water losses using an electric and magnetic field inducing device is disclosed. The device influences a liquid's properties including evaporation rate, diffusion, vapor, heat transfer rate, and/or fluid properties. The device comprises a malleable core with notches and electrically conductive windings wrapped around the flexible core around the notches. An insulative coating isolates the windings from the core. The device is pliable and is wrapped and/or attached around a conduit (e.g., a makeup line or pipe or a recirculating line or pipe of an evaporative cooling tower) with flowing fluid and current is passed through the windings to treat the fluid.
US11261108B2 Apparatuses and methods for treating, purifying and/or extracting from wastewater
An efficient, cost-effective, and efficacious technique for removing coal ash and other pollutants from waterways, ponds, marshes, holding tanks and other water sources and supplies. An apparatus comprising an open cage including electromagnets and/or permanent magnets and/or electrodes is supplied with electrical power to extract materials such as rare earth elements and/or heavy metals. The materials levitate to the surface, forming a shiny while leaving water substantially free of such materials.
US11261107B2 Desalination using pressure vessels
Disclosed techniques include desalination using pressure vessels. Access to a set of at least three pressure vessels is obtained. The pressure vessels are interconnected using piping and computer-controlled switching valves. A first pressure vessel of the set is filled with a prepurified liquid. A second pressure vessel of the set is filled with a pressurized gas. The pressurized gas is sharp interface immiscible with the prepurified liquid. The switching valves are controlled to enable the pressurized gas in the second pressure vessel to force the prepurified liquid from the first pressure vessel into a reverse osmosis chamber. The switching valves are controlled to enable a third pressure vessel of the set to fill with additional prepurified liquid. The switching valves are controlled to enable the pressurized gas that entered the first pressure vessel to force the additional prepurified liquid from the third pressure vessel into the reverse osmosis chamber.
US11261106B2 Methods for water blending control
Some embodiments of the invention provide a reverse osmosis water filtration system including a housing, a pre-filter cartridge, a reverse osmosis cartridge, and a post treatment cartridge. A medial water line transports a first portion of pretreated water from the pre-filter cartridge to the reverse osmosis cartridge. An unfiltered water line includes a flow restrictor and blend valve. The unfiltered water line is fluidly coupled between the medial water line and a blend water line. The blend water line receives filtered water at a first flowrate from the reverse osmosis cartridge and unfiltered water at a second flowrate from the blend valve. The first flowrate and the second flowrate are substantially equal to produce a consistent total dissolved solids value.
US11261105B1 Oil skimmer
An apparatus for removing oil or other pollutants from the surface of water, comprising a platform having a left side wall, a right side wall, a rear wall, a front opening, a floor, and a bottom, one or more ballasts which adjust the platform floor relative to a level of oil on the water surface, wherein the oil flows from the front opening across the floor to the rear wall, a rear location near the rear wall to collect the oil from the platform floor; and a pump connected to the rear location that removes the oil from the rear location to a storage area which does not affect the ballast of the platform. The skimmer vessel can work stationary in the water, and does not require a propeller means, as the oil will continue to flow into the skimmer as the oil is pumped out of the rear by the gravity flow to the rear of the vessel.
US11261102B2 Reverse osmosis prefilter system
A reverse osmosis prefilter system includes a recirculation chamber for accommodating one or more prefilter cartridges. The recirculation chamber is communicably interconnected to an inline water source and an RO filtration membrane. The recirculation chamber has a recirculation outlet and inlet which are communicably interconnected by an offline pump that recirculates prefiltered water repeatedly through the recirculation chamber and prefilter cartridges to remove particulates from the source water prior to delivery to the reverse osmosis filter membrane.
US11261100B2 Drying process
The present invention refers to a process for making a calcium carbonate containing material, wherein the process includes a specific drying procedure and allows for the provision of calcium carbonate materials with reduced moisture pick-up and low porosity.
US11261099B2 Process for the synthesis of ammonia
A dual pressure process for the synthesis of ammonia from a make-up gas, wherein the make-up gas is reacted in two steps in series, the second step operating at a greater pressure than the first step, and wherein a portion of the effluent of the first step is recycled back to the first step, said portion containing unreacted make-up gas.
US11261096B2 Controlled silicon polymer treatment method
A polymer inactivation method for a polycrystalline silicon manufacturing device, wherein the polymer byproducts are treated and additionally treated in a manner that controls the rate of reaction. The polymer byproducts are treated with a first inert gas under partial vacuum and a second oxygen containing gas to convert the polymer byproducts. The reaction rate can be controlled by regulating the fill pressure of reactant gas, controlling the amount of oxygen in the reactant gas, and stripping of the raw polymer with heat and or a vacuum. The solid byproduct remaining after treating the polymer, which is predominately silicon suboxides (SiOx) and silicon dioxide (SiO2), is inert and is easily removed.
US11261095B2 Control system and control method for recycling and smelting crushed silica from silicon plants
A manufacturing system and method for recycling and smelting crushed silica from silicon plants, including a crushed silica storage device, granulator, submerged arc furnace, transfer device, forming device and cooling system. Firstly silicon waste is collected, then crushed silica is output to a granulator. The granulator mixes the waste irregular crushed silica with water, and granulates and produces small particles having an uniform grain size as the raw material for smelting. The raw material is smelted in the submerged arc furnace. The forming device evenly pours the silicon liquid into the cooling system according to a set flow rate. The silicon liquid is solidified to form silicon pellets, and then a lift system is used to lift the formed silicon pellets, wherein the silicon liquid poured into the cooling system has a uniform diameter. The system can rapidly and efficiently smelt the silicon waste from the silicon plants.
US11261093B2 Method for nitrogen doping of solid materials
A process for the nitrogen doping of a material includes a set of carbon atoms in the sp2 hybridization state. The process further includes the material not being oxidized beforehand, then placing the material in contact with dinitrogen. Irradiating the material and the dinitrogen placed in contact with a beam of electrons or of light ions whose energy is greater than or equal to 0.1 MeV, to obtain a material wherein some of the carbon atoms in the sp2 hybridization state is nitrogen-doped.
US11261087B2 Method for preparing lithium bis(fluorosulphonyl)imide salt
A method for preparing Cl—SO2NHSO2Cl including a step of chlorinating sulphamic acid with at least one chlorinating agent and at least one sulphur-containing agent, the method resulting in a flow F1, preferably liquid, including Cl—SO2NHSO2Cl and a gas stream F2 including HCl and SO2, the method including a step a) of treating the gas stream F2. Also, a method for preparing LiFSl including the abovementioned method for preparing Cl—SO2NHSO2Cl.
US11261083B2 Fence structure to prevent stiction in a MEMS motion sensor
The present disclosure relates to a microelectromechanical systems (MEMS) package featuring a flat plate having a raised edge around its perimeter serving as an anti-stiction device, and an associated method of formation. A CMOS IC is provided having a dielectric structure surrounding a plurality of conductive interconnect layers disposed over a CMOS substrate. A MEMS IC is bonded to the dielectric structure such that it forms a cavity with a lowered central portion the dielectric structure, and the MEMS IC includes a movable mass that is arranged within the cavity. The CMOS IC includes an anti-stiction plate disposed under the movable mass. The anti-stiction plate is made of a conductive material and has a raised edge surrounding at least a part of a perimeter of a substantially planar upper surface.
US11261080B2 Fuel dispenser communication
Various systems, devices, and methods are provided for facilitating communication between a forecourt controller and a fuel dispenser. In certain aspects, a fuel controller translator is provided for translating commands transmitted between the forecourt controller and the fuel dispenser. For example, where the forecourt controller transmits commands that are compatible with the payment terminal, but not with the fuel controller, the fuel controller translator can translate the commands received from the forecourt controller into a format compatible with the fuel controller. Conversely, the fuel controller translator can translate commands received from the fuel controller into a format that is compatible with the forecourt controller.
US11261078B2 Methods and systems for on demand fuel supply
An improved fill cap for delivering a fluid from a fluid transporting mechanism to a fluid tank is disclosed. A connection plate is coupled to an opening of the fluid tank and a probe is disposed within the fluid tank and coupled to the connection plate at a first distal end. The fluid flows into the fluid tank through an outlet at a second distal end of the probe. A valve is disposed at the second distal end of the probe and is movable between an open position and a closed position to control fluid flow out of the probe outlet. An arm is coupled to the valve and moves the valve between the open and closed positions and a float is coupled to the arm that moves the arm depending on the level of fluid in the fluid tank.
US11261076B1 Beverage dispense monitoring with camera
A beverage dispenser includes a nozzle to dispense a beverage. The beverage dispenser further includes a camera to capture an image of the beverage as the beverage is dispensed from the nozzle. The camera has a field of view that includes the beverage. The beverage dispenser further includes a light source that illuminates the field of view of the camera. The beverage dispenser further includes a computer. The computer analyzes the image of the beverage and determines a characteristic of the beverage.
US11261075B2 System and method for determining a liquid level in a vessel
A system and method for determining a liquid level in a vessel is described. Embodiments of the system can include a liquid level measuring assembly, a user device, and a vessel. The liquid level measuring assembly can include an ultrasonic sensor assembly, a control module, and a mount body configured to place the ultrasonic sensor assembly proximate a bottom of a vessel. Typically, the system can be implemented with a vessel having a substantially cylindrical shape and including a chime. The mount body can be adapted to removably couple to the inside of the chime of the vessel.
US11261074B2 Apparatus for dispensing a mixture of at least two liquid components
Disclosed herein is an apparatus for dispensing a mixture of at least two liquid components. The apparatus may comprise an A liquid component source fluidly connected with an A liquid component pump driven by a first motor; and a B liquid component source fluidly connected with a B liquid component pump driven by the first motor. Each of the A liquid component pump and the B liquid component pump may comprise at least two chambers. The A liquid component pump and the B liquid component pump may be fluidly connected with a dispenser unit. There may be one or more A liquid temperature regulators between the A liquid component pump and the dispenser unit. Similarly, there may be one or more B liquid temperature regulators between the B liquid component pump and the dispenser unit.
US11261067B1 Waste pump removal apparatus
A waste pump removal apparatus for removing pumps from reception areas for maintenance. The waste pump removal apparatus includes a frame having front and back ends, a top and a bottom; a loader attachment coupled to the back end of the frame and adapted to mount to a loader; a pump attachment pivotably connected to the front end of the frame and adapted to be coupled to a waste pump; and an actuator mounted to the frame and in communication with the pump attachment for pivoting the pump attachment relative to the frame to remove the waste pump from a reception area.
US11261059B2 Elevator drive machinery and elevator
The invention relates to an a drive machinery for an elevator, the drive machinery comprising a rotatable drive sheave for driving plurality of ropes of the elevator, the drive sheave comprising a central cylinder, which comprises a central axis around which the central cylinder is rotatable; plurality of circular rim members surrounding the central cylinder, each said rim member comprising an outer rim surface for engaging a rope. Said plurality of circular rim members includes one or more rotatably mounted circular rim members, each said rotatably mounted circular rim member being mounted on the central cylinder rotatably around said central axis relative to the central cylinder and relative to one or more of the other circular rim members, and in that said drive sheave moreover comprises a control means for controlling rotation of each said rotatably mounted circular rim member relative to the central cylinder and relative to one or more of the other circular rim members. The invention also relates to an elevator implementing the drive machinery.
US11261058B2 Travelling cable support arrangement of an elevator
The arrangement comprises at least one travelling cable, a guide rail extending from a pit floor at least to a middle of an elevator shaft, an intermediate fixing point positioned in connection with the guide rail, the at least one travelling cable being fixedly attached in said intermediate fixing point, a travelling cable keeper being movably supported on the guide rail so that the travelling cable keeper is movable upwards and downwards along the guide rail, the at least one travelling cable being movably supported in support points on the travelling cable keeper, a path of the at least one travelling cable through the support points in the travelling cable keeper being curved, the at least one travelling cable being movable through the support points.
US11261057B2 Elevator guide
An elevator guide having a base attached to an elevator component, a guide riding along a portion of a rail and a spring biasing the guide in contact with the rail. The guide includes one or more of the following: (i) a guide support member operably associated with the guide for movably supporting the guide so that the guide can move toward and away from a corresponding surface of the rail member wherein the guide support member has a plurality of spring engagement sections configured to vary a system effective spring rate; (ii) a roller including a non-metallic rim molded about a bearing; (iii) two independently adjustable stops and, (iv) an opening adjustment member mounted about a notch in the base to vary the distance between the base and the rail. The opening adjustment member has a width and/or depth greater than a width and/or depth of the notch.
US11261054B2 Method of generating buttons for car operating panels
A computer-implemented method of automatically generating and populating one or more car floor buttons on a configuration tool display wherein the configuration tool is in communication with an elevator cabin of an elevator system.
US11261051B2 Sheet conveyance apparatus and image forming apparatus
A sheet conveyance apparatus include a first conveyance unit, a second conveyance unit including a cover and configured to be movable between a first position where a sheet conveyed from the first conveyance unit can be conveyed to a sheet conveyance path and a second position separated from the first position, and a retaining portion configured to retain the cover at an open position and to retain the second conveyance unit at the second position through the cover retained at the open position in a case where the cover is positioned at the open position in a condition in which the second conveyance unit is positioned at the second position.
US11261047B2 System for delivering printed products of identical or different thickness and method for their transfer to a delivery system
A system has: a transport chain, which is roof-shaped in an upper region, along which printed products are transportable astride, collectable, and optionally stitchable in an intermediate stitching station; and a stop, which is adjustable in accordance with a format of a printed product of the printed products being delivered, is arranged in a transport direction of the printed products, and is positioned after the intermediate stitching station along the transport chain, the stop corresponding to a location of delivery of the printed product from the transport chain. A cyclic transfer of the printed product during the delivery takes place via a delivery system, the delivery system having in an infeed region a printed product transporter configured to transfer the printed product being delivered, the printed product transporter having pivot arms, the pivot arms being controllable according to a measured thickness of the printed product being delivered.
US11261045B2 Rewinder winding methods and apparatus
A converting line includes a rewinding machine for winding web material into a log. For time points during a time period of the log wind cycle, predictive information representative of a log to be wound is generated and stored in a memory of a control of the rewinding machine. An image capture device is enabled to capture a plurality of images of the log being wound in the winding nest at the plurality of corresponding time points during the time period. Log image capture information is generated based upon the plurality of captured images and corresponding time points during the time period. The log image capture information is compared with the generated predictive log image information to determine a difference in log image. Revised predictive log image information is generated based at least in part upon a difference in the log image capture information relative to predictive log image information.
US11261041B2 Automated and remotely-controlled material-conveying systems and methods
A material-conveying system comprises a main conveyor for conveying material, a swing conveyor for conveying the material to the main conveyor and a processor for controlling a speed of the swing conveyor based on a feedback signal. The feedback signal may be indicative of a speed of the swing conveyor and/or a speed of a main conveyor. The feedback signal may be indicative of material level, belt slippage, flow rate, belt angle and/or material rollback.
US11261033B2 Combination weighing device
A combination weighing device includes a plurality of weighing units arranged in a circular form, a combination scale configured to temporarily retain, in a collection hopper, articles discharged from one or more of the weighing units selected as a result of combinatorial computations and to discharge the articles from the collection hopper, and an alignment and transport unit configured to align and vibrationally transport the articles discharged from the collection hopper.
US11261031B2 Conveyor pan
A conveyor pan for a chain scraper conveyor comprises a bottom plate and a pair of side profiles fixed to the bottom plate by welding. The conveyor pan has an increased wear resistance, in particular due to a specific geometry of a weld groove formed between the profile rails of the side profile and the bottom plate. The weld groove extends deeper into each profile rail, resulting in a more durable weld connection during use of the conveyor pan. In addition, a geometry of a pocket member for connecting adjacent conveyor pans and an inspection opening formed in the bottom plate have also been improved to result in an increased strength of the conveyor pan.
US11261028B2 Wear liners
The present invention relates broadly to a wear liner module (10) for equipment in a high wear environment, said module (10) comprising a back plate (12) and a wear liner (11) including one or more tiles (14a) to (14f) formed of wear resistant material, and one or more sensors such as (16a) mounted to the wear resistant tile such as (14a). The wear sensor (16a) is mounted to a perimeter face of the corresponding wear resistant tile (14a). The wear sensor (16a) is electrically coupled to a microprocessor mounted to a rear face of the tile (14a). The microprocessor is configured to process data received from the wear sensor (16a) to provide a wear signal represented of wear in the wear sensor (16a). The microprocessor (24a) transmits the wear signal to a wireless receiver (34a) mounted to the backing plate (12).
US11261026B2 Container stacking storage system loading trolley having first and second lift drives
A container stacking storage system loading trolley that includes a chassis and a container seat that is height-adjustable relative to the chassis. The container seat includes a receiving region with a container contact surface. A lifting device, operable in a lifting direction, is arranged between the chassis and the container seat, and includes a first lifting drive and a second lifting drive. The second lifting drive is configured to act on an unlocking device that is configured to act on holding elements of a container stacking storage system.
US11261024B2 High density stocker
An article storage device is provided for holding a plurality of standardized containers. The standardized containers extend between a bottom surface extending generally horizontally and a top surface spaced from and generally parallel to the bottom surface. The standardized containers further include an opening side perpendicular to the top and bottom surfaces and a door flange extending along the opening side and beyond the top surface. The standardized containers further include a lifting flange attached to the top surface for receiving a lifting tool. The standardized containers are disposed in the storage rack with their respective opening sides facing away from an access space for allowing a retrieval transport apparatus to move in a substantially horizontal plane between the access space to engage the lifting flange without being obstructed by the door flange.
US11261021B2 Aerosol spray can
An aerosol spray can has a can body, a valve assembly, a dip-tube assembly and a rigid tube. The valve assembly is mounted on the can body. The dip-tube assembly is connected to the valve assembly and has a head end channel-linked to the valve assembly. The dip-tube assembly has a flexible tube and a weight piece. The two ends of the flexible tube are connected to the valve assembly and the weight piece respectively. The rigid tube is sleeved around the flexible tube to constrain excessive bending of the flexible tube. The flexible tube protrudes from the rigid tube. The weight of the weight piece drives the tail end freely toward the ground. Therefore, the tail end stays submerged under a liquid product when less than a half of the liquid product is left inside the can body even when the can body is tilted or horizontal.
US11261015B2 Beverage container packaging
A beverage container packing assembly includes a bottom tray defining a plurality of first compartments. The first compartments receive a first portion of a beverage container. The bottom tray includes first support columns. The beverage container packing assembly includes a center support defining through holes. The through holes receive a second portion of a beverage container therethrough. The center support includes second support columns configured to stack on the first support columns. The center support is configured to accommodate a thermo pack between a first row and a second row of the through holes. The beverage container packing assembly includes a top tray defining second compartments. The second compartments to receive a third portion of a beverage container therein.
US11261009B2 Removable cap for a dispensing bottle
A removable cap for a dispensing bottle of a fluid product, equipped with a central axis, includes an axis insert being capable of concealing a dispensing system of the bottle. The insert includes a peripheral portion and an upper portion, a first decorative element mounted on the insert and covering the peripheral portion of the insert, a second decorative element mounted on the insert and covering the upper portion of the insert. The second decorative element engages with the first decorative element so as to integrate decorative protrusions within the first decorative element, arranged on the periphery of the cap. The decorative protrusions are arranged on lugs.
US11261008B2 Sheet material container
A sheet container has, formed in the bottom face of the container body, a non-attached part where the film layers are left partially unattached to each other. An filled part is formed by enclosing a filler between the film layers at the non-attached part. A side part of the filled part is a side bulging part bulging toward the skirt part. The side bulging part presses a pressed part above the lower edge of the skirt part from the inside toward the sideward. The lower edge of the skirt part is disposed inwardly from the pressed part.
US11261005B2 Modular utility bottle
A modular bottle (e.g., for holding liquid or dry storage contents) and its various assemblies, components, and structures are provided. The bottle can be flexible or rigid and is dynamically modular to be particularly useful for outdoorspeople, military personnel, travelers, pet owners, and the like. The bottle is a double-ended device capable of being modified or expanded with various caps, filters, spouts, compartments, and like accessories.
US11261002B2 Resin made container
A resin made container includes a spout portion to/from which a cap can be attached/detached, a shoulder portion continuous with the spout portion, a body portion continuous with the shoulder portion and a bottom portion continuous with the body portion and disposed at a lowermost part. A decompression absorption portion provided in form of a recess in the body portion includes a bulging area protruding to the outer side of the container.
US11260999B2 Thermoforming packaging machine with film deflection
A thermoforming packaging machine that includes a film holder for receiving a lower film supply roll and one behind the other in a sequential arrangement along a production direction a pretreatment station for pretreating the lower film web, a forming station for forming troughs in the lower film web by thermoforming, an insertion line for filling the troughs with products and a sealing station for sealing the troughs with a top film. A transport device is configured to transport the lower film web along the production direction through the pretreatment station, further to the forming station, further to the insertion line and finally to the sealing station. A deflection unit arranged at least partially below the pretreatment station is configured to deflect the lower film web before reaching the pretreatment station. The pretreatment station may include a punching or slitting unit to punch or slit the lower film web.
US11260998B2 Vacuum suction nozzle and vacuum suction apparatus including the same
Disclosed are a vacuum suction nozzle for improving vacuum suction performance and a vacuum suction apparatus including the same. The nozzle includes blade portions extending from both sides thereof so as to reduce a gap occurring between the nozzle and an outer skin material for a vacuum insulation panel (VIP) or other vacuum wrapping paper when the outer skin material or vacuum wrapping paper is sealed, thereby minimizing the occurrence of a leak and thus enabling efficient vacuum suction. Further, the nozzle achieves efficient vacuum suctioning by ensuring a suction channel inside the vacuum insulation panel (VIP) or other vacuum wrapping paper through a protrusion extending to the front of the nozzle.
US11260996B2 Lunar orbiting satellite system, and ground station of lunar orbiting satellite system
A lunar orbiting satellite system executes orbit planning of assigning a function (positioning, communication, and flashing) to an artificial satellite (AS) depending on a relative position of the AS to the moon at a time when the moon and the AS are observed from an input point on the earth, and correcting the relative position, which changes in accordance with the moon revolution period. The system includes: a satellite orbit planner which assigns a function to each ASs forming an AS group flying around the moon depending on a relative position of each ASs to the moon at a time when the moon and ASs are observed from an input point on the earth, and set a target orbit according to the function; and a satellite controller which causes the each ASs to execute control based on the function to implement switching of the function.
US11260995B2 Spacecraft high tensile fabric barrier for hot re-entry gases
A multi-layer shell structure for a vehicle and method of providing a multi-layer shell structure for a vehicle. The multi-layer structure includes a thermal protection system (TPS) layer, a structural layer connected to the TPS layer, and a high tensile fabric barrier layer bonded to the structural layer. Room-temperature-vulcanizing silicone may be used to bond the TPS layer to the structural layer and bond the high tensile fabric barrier layer to the structural layer. The high tensile fabric barrier layer may create a seal on the structural layer. The multi-layer shell structure may include inner shell enclosing a passenger and/or cargo compartment and an annulus between the inner shell and the high tensile fabric barrier layer. The high tensile fabric barrier layer may prohibit entry of gas into the annulus in the event a hole is created through a portion of the multi-layer shell structure.
US11260991B2 PAPI with LED light source and aperture plates
A precision approach path indicator (PAPI) employs an LED light source with first and second arrays of LEDs or other efficient light sources, disposed one above the other and emitting their respective color lights along an optic axis to a collimating lens of focal length f. First and (optional) second aperture plates positioned along the optic axis, each being a respective frame with a cut-out defining a horizontally elongated aperture for light passing along the optic axis. Intermediate aperture plate(s) can be positioned between the first and second aperture plates. The first frame is positioned between the light source and the collimating lens at the focal distance f from the lens. The optional second aperture plate is positioned at the collimating lens and covers top, bottom, and side edge portions of the lens. A planar blade extends from the light source to the first frame and has a distal edge extending across the aperture of the first aperture plate, substantially at the focus of the collimating lens, dividing the beam into white and red sectors. The intermediate aperture plate(s) can be adjusted for optimal separation. The PAPI can be considered to have an illumination portion formed of the light source(s), blade, and first frame; and an imaging portion formed of an enclosure and a lens positioned at its focal length distant from the front frame aperture and edge of the blade.
US11260990B2 Naval platform provided with a zone for the deck landing/take-off of at least one aircraft and dolly-type means for handling said aircraft
Disclosed is a naval platform equipped with a deck-landing/takeoff zone for at least one aircraft and dolly-type mechanism for handling the aircraft to move it over the deck-landing/takeoff zone. The dolly-type mechanism includes a vacuum disc for immobilizing the dolly and thereby securing the aircraft in position on the deck-landing/takeoff zone, the operation of which is triggered by an analyzer of the behavior of the platform in order to avoid any risk of uncontrolled movement of the aircraft.
US11260984B2 Aircraft refueling safety system
A system ensures the correct type of fuel is dispensed in an aircraft while removing the introduction of human error in the refueling process. The system includes an RFID tag disposed at one or more aircraft that electronically stores data such as engine type, engine hours, fuel type, tail number, and pilot/subscriber data for the aircraft on which the RFID tag is disposed. An RFID reader is disposed at or near a fuel dispensing mechanism, such as a fuel truck or tank. A signal indicative of fuel type is emitted from the RFID tag to the RFID reader. RFID tags on aircraft that are enrolled in the system's subscription service enable aircraft to be recognized by a module operating the fuel dispensing mechanism. Based on a comparison performed by the module, authorization to begin fueling is either permitted or declined.
US11260975B2 Paired herringbone high density business class seating arrangement
Described are seating arrangements having at least one set of columns that include an aisle column of seating units positioned adjacent a wall column of seating units. The aisle column is positioned adjacent an aisle, and the wall column is positioned adjacent an exterior wall. Each seating unit has a bed position having a head end and a foot end, wherein at least a height-limited portion of the foot end is less than a delineating height that separates a lower portion of the aisle from a upper portion of the aisle. The seating units in the adjacent columns are longitudinally aligned and positioned adjacent one another, as well as being angled with respect to each other. The height-limited portion of the foot ends in the aisle column is positioned adjacent the aisle, and the height-limited portion of the foot ends in the wall column is positioned within a concave portion of the exterior wall.
US11260974B2 Aircraft aerosol dispensing method, apparatus, and system
A method, system and apparatus are provided for generating and dispersing plumes of reflective aerosols. Methods include: supplying fuel to an engine of an aircraft for combustion; supplying an additive to the fuel, where the additive includes at least one of a reflective aerosol or a precursor thereof; combusting the fuel and the additive to the fuel in the engine; and generating, in the exhaust from the engine, a plume of reflective aerosol, where the reflective aerosol reflects sunlight.
US11260972B2 Systems and methods for a foldable unmanned aerial vehicle having a laminate structure
Various embodiments of a foldable unmanned aerial vehicle having a multi-layer laminate structure and extendible arms are disclosed.
US11260971B2 Enclosed unmanned aerial vehicle
The present disclosure is directed to a propeller driven remote control flying device having an enclosed body. The motor and propellers of the device can be contained within the enclosed body. The enclosed body can include a plurality of pores through which air passes, with one side of the body generally functioning as an air intake, and the opposite side of the body functioning as an air outlet. The pores can be sufficiently small so as to prevent contact between persons, animals or articles and the motor driven propellers.
US11260970B2 Autonomous home security devices
An aerial vehicle is programmed or configured to respond to reports of events or conditions within spaces of a facility. The aerial vehicle travels to a location of a reported event or condition and captures data using onboard sensors. The aerial vehicle independently determines whether the reported event or condition is occurring, or is otherwise properly addressed by resources that are available at the location, using images or other data captured by the onboard sensors. Alternatively, the aerial vehicle transmits a request for additional resources to be provided at the location, where necessary. A map of the location generated based on images or other data captured by the onboard sensors may be utilized for any purpose, such as to make one or more recommendations of products that are appropriate for use at the facility.
US11260964B2 Aircraft assembly including a wing tip device
An aircraft assembly is disclosed having a wing tip device connected to a wing tip of a wing by a first connector, a second connector, and a third connector. The wing tip device includes a front device spar and a rear device spar. The first connector is associated with the rear device spar. The second connector is spaced apart in a chordwise direction forward of the first connector, and the third connector is spaced apart in a chordwise direction rearward of the first connector. The third connector includes a spigot mounting formation.
US11260961B2 Aircraft hydraulics
A hydraulic system 300 for an aircraft including a backup hydraulic pressure source 216 to provide hydraulic pressure to a brake 222 in the event of a failure condition of a primary hydraulic brake pressure source. The hydraulic system 300 also includes a landing gear backup system to provide hydraulic pressure to enable extension and/or retraction of landing gear 100. The backup hydraulic pressure source 216 is arranged to provide hydraulic pressure to the landing gear backup system in the event of a failure condition of a primary landing gear hydraulic pressure source.
US11260959B2 Integrated thrust and drag control of an aircraft
Aircraft, auto speed brake control systems, and methods for controlling drag of an aircraft are provided. In one example, an aircraft includes an aircraft structure. A drag device is operatively coupled to the aircraft structure between a stowed and a deployed position and/or an intermediate deployed position. A speed brake controller is in communication with the drag device to control movement. An autothrottle-autospeedbrake controller is in communication with the speed brake controller and is configured to receive data signals. The autothrottle-autospeedbrake controller is operative to direct the speed brake controller to control movement of the drag device between the stowed position and the deployed position and/or the intermediate deployed position in response to at least one of the data signals.
US11260957B2 Rupture fairings
Rupture fairings are disclosed. A disclosed example fairing for use with an aircraft includes a surface to at least partially define an exterior surface of the aircraft when the fairing is installed onto the aircraft, and a membrane to rupture during flight of the aircraft, where the membrane defines at least a portion of the exterior surface.
US11260954B2 Apparatus for attaching aircraft wing structural components
Examples include an apparatus configured for attaching a rib of an aircraft wing to a panel of the aircraft wing, the apparatus including: an insert that is configured to be attached, via an interference fit, to a hole in the rib; a shear tie including a socket at a first end of the shear tie, where the shear tie is configured to be attached to the panel at a second end of the shear tie; a ball stud including a shaft and a ball that is opposite the shaft, where the shaft is configured to be attached to the insert and the ball is configured to be positioned within the socket; and a fastener that is configured to secure the ball within the socket, thereby attaching the ball stud to the shear tie.
US11260952B2 Reinforced superplastic formed and diffusion bonded structures
An exterior panel is formed of superplastic materials, including an exterior skin of titanium to accommodate high thermal stresses imposed on hypersonic transport vehicles during hypersonic flight. The exterior skin is fixed to an underlying reinforcing skeletal structure consisting of a superplastic formable reinforcement (SFR) layer, for example a titanium, zirconium, and molybdenum (TZM) alloy, which supports the exterior skin whenever the latter may be heated to temperatures exceeding 1200 degrees Fahrenheit. The exterior panel includes a separate interior skin configured for attachment to a frame member such as a rib, stringer, or spar of the hypersonic transport vehicle. A multicellular core is sandwiched between the exterior and interior skins to impart tensile and compressive strength to the exterior panel. In one disclosed method, the core is superplastic formed and diffusion bonded to the exterior and interior skins.
US11260949B2 Marine vessel station keeping systems and methods
A system for maintaining a marine vessel in a body of water at a selected position and orientation includes a global positioning system that determines a global position and heading of the vessel and a proximity sensor that determines a relative position and bearing of the vessel with respect to an object near the vessel. A controller operable in a station keeping mode is in signal communication with the GPS and the proximity sensor. The controller chooses between using global position and heading data from the GPS and relative position and bearing data from the proximity sensor to determine if the vessel has moved from the selected position and orientation. The controller calculates thrust commands required to return the vessel to the selected position and orientation and outputs the thrust commands to a marine propulsion system, which uses the thrust commands to reposition the vessel.
US11260947B2 Outboard motor and marine vessel
An outboard motor includes an engine, a drive shaft, and a shift shaft disposed forward of the drive shaft. The shift shaft includes a first shift shaft that extends in an upward-downward direction, a second shift shaft disposed below the first shift shaft and spaced apart from and rearward of the first shift shaft, the second shift shaft extending in the upward-downward direction, and a shift force transmission to transmit, to the second shift shaft, a shift force applied to the first shift shaft.
US11260944B2 Device and system for detecting a signal for locating an underwater source
A device (10) for detecting a signal of interest in order to locate an underwater source of the signal. The device includes a receiver (13) configured to detect the signal of interest, an actuator (14) configured to allow at least a portion of the detection device (10) to move towards a zone indicating a result of detection of the signal of interest in response to the receiver being operated, and an emitter (15) configured to indicate the result of detection of the signal of interest.
US11260940B2 Underwater towing test device
An underwater towing test device including a driving mechanism, an observation platform disposed under the driving mechanism, a towing member, and a towed body. The driving mechanism includes an operation platform, an extended platform connected to the operation platform, a crane, a first railing, a lifebuoy, a control center, a power distribution room, and a plurality of bus ports. The operation platform includes two rail grooves disposed in parallel and a moon pool provided with two pool slots on both ends thereof. The crane includes a chassis provided with a plurality of first guide rollers. The first railing is positioned along the edge of the operation platform and the extended platform, with the lifebuoy hanging thereon. The control center, the power distribution room, the plurality of bus ports, and the moon pool are fixedly disposed on the operation platform.
US11260939B2 Adjustable height spring-biased support pole
A spring-biased support pole 10 for supporting a boat cover 40 over a boat during transport of the boat as well as docking of the boat. The support pole comprises a base 14 and a support rod system 100 connected to the base. The support rod system comprises at least two support rod sections 110, 120 that are telescopically connected to one another and a spring 20. The spring is positioned between the telescoping connection of a first support rod section and a second support rod section, such that the spring controls vertical movement of the second support rod section with respect to the first support rod section and provides a biasing force that is applied to the second support rod section and to the cover supported by the support pole.
US11260938B2 Rear wheel sprocket arrangement
A bicycle rear wheel sprocket arrangement which is rotatable about a common sprocket rotation axis that defines an axial direction and orthogonal to which are radial directions, comprising a plurality of sprockets of different sizes and number of teeth arranged coaxially along the sprocket rotation axis, which are connected to one another such that the sprockets jointly rotate about the sprocket rotation axis together, wherein the sprocket arrangement comprises a first partial arrangement that includes a largest sprocket, and a second partial arrangement that includes a plurality of sprockets formed integrally with one another. One partial arrangement has a plurality of elastically deformable latching formations that are in latching engagement with a plurality of mating latching formations of the other partial arrangement to prevent the two partial arrangements from separating in the axial direction.
US11260936B2 Gearless power conversion system employing two electric machines
A human power conversion system incorporates two or more electric machines to aid in the powering of a vehicle through energy conversion. A first electric machine is coupled with the human powered input and acts as a generator when a human power input is not sufficient to produce electrical power that is provided to a second electric machine that propels the vehicle. The vehicle may be a bicycle and the first electric machine may be coupled to the crank. A bi-coupled electric machine including the first and second electric machines with a common rotor or stator may be employed and coupled to the crank and/or the driven wheel. Power produced by the first electric machine may be provided directly to the second machine or may be stored in a battery and used to propel the vehicle or power other electronic components.
US11260931B2 Body frame of saddle riding vehicle
In a body frame, a pair of left and right main frames extend downward to the rear from the upper portion of a head pipe and a down frame extends downward to the rear from the lower portion of the head pipe, a gusset is provided in the body frame, the gusset being joined to the head pipe, and the gusset includes a center wall portion and lower extension portions, the center wall portion being disposed between inner side wall portions of the left and right main frames, the lower extension portions extending downward from the center wall portion and being joined to outer side surfaces of the down frame.
US11260930B2 Foldable bicycle frame
A foldable bicycle frame includes a rigid element connecting a head with a seat tube, a rear section of the frame, a coupler, and an intermediate seat tube. The front upper part of the rear section of the frame is pivotally connected to the intermediate seat tube. The front bottom part of the rear section of the frame is pivotally connected to the coupler. The other end of the coupler is pivotally connected to the rigid element. The intermediate seat tube is operable to be inserted into the seat tube while unfolding the frame.
US11260926B2 Folding portable electric scooter
A three wheeled stand-up or sit down foldable and portable electric personal mobility vehicle for fulfilling the needs of a broad spectrum of users including the handicapped and recreational users. The personal mobility vehicle has two major parts, including a front wheel frame assembly and a rear frame chassis assembly. These major parts are configured to easily fold into a smaller size so that the vehicle can be easily transportable and more conveniently stored. Furthermore, a versatile seat and seat post are implemented to enable a user to sit or stand, and the seat can be easily removed, without tools, to create more space should a user wish.
US11260923B2 Four-wheel off-road vehicle having an anti-lock braking system assembly
An off-road vehicle has two front wheels and two rear wheels, the rear wheels being connected to a spool gear driven by a motor. The vehicle also has a left front brake, a right front brake and a single rear brake. Speeds of left and right front wheels are respectively monitored by left and right front speed sensors. A single sensor monitors a common speed of left and right rear wheels. Two user actuated braking input devices, for example a hand lever and a foot lever, may be used independently or concurrently to provide a braking command. An anti-lock braking system may use speed measurements from the various speed sensors to control selective application of pressure on the left front brake, the right front brake and the rear brake.
US11260920B2 Front fender assemblies for a work vehicle
A track work vehicle includes a track system. The track system includes a drive wheel supported by an axle housing that drives a continuous ground-engaging track, a saddle assembly that guides the track about the drive wheel and an undercarriage frame that supports one or more idler wheels that guide the track along a ground surface. The track work vehicle includes a fender assembly that includes at least one fender coupled to the track system to overlap a portion of the track.
US11260919B2 Assembly for converting a wheel drive harvester to track drive
A retrofit assembly for conversion of a wheel driven vehicle to track drive, the vehicle having an undercarriage and left and right final drive mounts, the assembly incorporating left and right setback arms attached to and extending rearwardly from the vehicle's left and right final drive mounts; a “U” bracket having left and right “U” arms, the “U” bracket being fitted for laterally spanning the vehicle's undercarriage, wherein distal ends of the left and right “U” arms are fixedly attached to rearward ends of the left and right setback arms, and wherein forward ends of the setback arms are fixedly attached to the vehicle's left and right final drive mounts; left and right final drives respectively fixedly attached to the rearward ends of the left and right setback arms; and left and right sprocket driven tracks, wherein the track's sprockets are fixedly attached to the left and right final drives.
US11260918B2 System for a vehicle shell
Systems and methods are provided for a vehicle bed shell. The system includes a pair of sidewalls with each including a top portion and two horizontal railings. The sidewalls are coupled to parallel sides of a bed of a vehicle. The system also includes at least one cross beam coupled perpendicularly to each of the horizontal railings of the sidewalls configured to stabilize each sidewall. The system also includes a plurality of cylindrical inserts, including a bottom. The system also includes a hinge element, with a sleeve, one or more hinge plates, and a vertical railing. The hinge element is coupled to a back side of each of the sidewalls, and the sleeve and the one or more hinge plates are configured to slide along the vertical railing. The system also includes a back wall that is coupled to at least one of the sidewalls via the hinge element.
US11260915B2 Vehicle side body structure
A vehicle side body structure can secure a vibration-damping property of a body regardless of design specification by including a rear wheel house including a wheel house outer and a wheel house inner; a side sill extending forward from a front end of the wheel house outer; and an outer reinforcement extending in a vertical direction along a door opening edge from an intermediate portion in a front-rear direction of the wheel house outer. The wheel house outer includes: an outer overhang overhanging outward; and an outer flange extending upward from an inner end of the outer overhang. A reinforcing member is provided to cooperate with the outer overhang and the outer flange so as to define a closed cross section in a substantially triangular shape. The reinforcing member couples a rear end of the side sill and a lower end of the outer reinforcement.
US11260914B2 Holder for an interior trim part, and vehicle body structure
A holder for an interior trim part, in particular for covering the passenger compartment of a motor vehicle, has at least one supply line for guiding a temperature-controllable, liquid or gaseous fluid, to an outlet via which the fluid can emerge from the supply line, and an inlet via which the fluid can enter a discharge line. An interior trim part can be arranged on the holder in such a manner that the outlet of the holder is fluidically connected to an inlet of the interior trim part, and the inlet of the discharge line of the holder is fluidically connected to an outlet of the interior trim part.
US11260913B2 Front pillar structure for vehicle
A front pillar structure for a vehicle includes a front pillar including a front pillar lower extending vertically and a front pillar upper extending obliquely from the front pillar lower. A connection member is coupled to a bottom end of the front pillar lower and connects a front side member and a side sill. The front pillar lower has an S-shaped cross section and the connection member has stepwise flanges coupled to the bottom end of the front pillar lower.
US11260910B2 Suspension member
A suspension member includes a side rail. The side rail is formed in a closed sectional structure by combining an upper member, a lower member, and a reinforcing member located between the upper member and the lower member. The upper member and the reinforcing member are fixed by welding and form a closed cross section having an upper hollow portion. The reinforcing member and the lower member are fixed by welding and form a closed cross section having a lower hollow portion. A distance from an upper end to a lower end of the upper hollow portion in a vertical direction in the lower bending portion is longer than that in the upper bending portion, and a distance from an upper end to a lower end of the lower hollow portion in the vertical direction in the upper bending portion is longer than that in the lower bending portion.
US11260909B2 Vehicle chassis platform
A vehicle chassis platform including: a frame having a front frame end, a rear frame end, a longitudinal frame axis, an upper frame surface, a bottom frame surface, a first longitudinal lateral frame surface and a second longitudinal lateral frame surface, wherein the upper frame surface is substantially flat; and two or more mechanical connection assemblies each coupled to one of the first and second longitudinal lateral surfaces, each of mechanical connection assemblies to couple a vehicle corner module (VCM) to the frame and to transfer mechanical loads between the frame and the VCM when the VCM is coupled to the frame.
US11260905B2 Human-machine interaction vehicle
A human-machine interaction somatosensory vehicle is provided. The human-machine interaction somatosensory vehicle may include a vehicle body and two wheels mounted on the vehicle body. The two wheels may rotate around the vehicle body in a radial direction. The vehicle body may include a support frame, two pedal devices mounted on the support frame, a controller, and a driving device configured to drive the two wheels. The support frame may be an integral structure rotatably connected to the two pedal devices. The two pedal devices each may include a pedal foot board and a first position sensor. The first position sensor may be mounted between the pedal foot board and the support frame, and configured to detect stress information of the pedal device. The controller may be configured to control the driving device to drive the two wheels to move or turn based on the stress information of the pedal devices.
US11260903B2 Variable linkage for tie-rods
Apparatus, systems, and methods that include a variable length linkage for connecting together tie rods. The linkage includes first, second, and third apertures. There is a first distance between the first aperture and the second aperture and a second distance between the first aperture and the third aperture. The apparatus may include a fourth aperture having a third distance between the first aperture and the fourth aperture. The second, third, and fourth apertures may each have a non-circular cross-section. The linkage may include a base, a first finger, a second finger, and a third finger that each extend from the base. The first aperture may be in the base, the second aperture may be in the first finger, the third aperture may be in the second finger, and the fourth aperture may be in the third finger. The first aperture may be oriented vertically with the other apertures oriented horizontally.
US11260895B2 Locking device and steering column assembly
A locking device for an adjustable steering column assembly of a motor vehicle is described, comprising an operating unit which has at least one closed and one open position, a control element coupled to the operating unit, and at least one eccentric part which is actuated by the control element. A retaining part is provided, which interacts with the eccentric part in the closed position, wherein a locking portion of the eccentric part engages on an engaging portion of the retaining part in the closed position. The eccentric part has a force transmission portion which is substantially opposite to the locking portion, wherein the force transmission portion in the closed position rests against a support surface lying substantially opposite to the engaging portion. Furthermore, a steering column assembly is described.
US11260894B1 Cargo sled assembly
A cargo sled assembly for facilitating a physically limited user to transport cargo includes a dish that has a rigid bottom wall to facilitate the dish to be dragged along a variety of support surfaces. The dish has a diameter of at least 40.0 inches to accommodate cargo such as yard debris or the like thereby facilitating the dish to transport the cargo. A pair of straps is each coupled to and extends laterally away from the dish. A rod is coupled between each of the straps and the rod can be gripped by a user thereby facilitating the user to drag the dish along the support surface. In this way the user can transport the cargo in the dish.
US11260893B2 Portable device for rocking a stroller in order to pacify the child without conditioning it
Rocking device for a stroller (2), including at least one main element (10) provided with a motor (40) and rolling means (21, 23) on its lower face, the motor and the rolling means being designed to drive the main element in a back and forth movement, the upper face of the main element (10) being designed to take a wheel (3) or (4) of the stroller. The rolling means are designed to roll on the ground and the device comprises a means for automatically starting the back and forth movement as a result of a deliberate action on the part of the user in pushing the stroller (2) so as to drive the main element (10) at least once in a first direction and at least once in the direction opposite to the first direction.
US11260891B2 Water heater articulation tool
A tool can aid in articulating a water heater onto, and off of, an elevated pedestal. The tool can consist of at least a frame that is pivotally attached to a stationary base via a fulcrum feature. The frame may be sized to support a water heater with at least a pair of rails. The stationary base can have at least one rigid pivot stop cantilevered from a base body and shaped to maintain the stationary base at a non-normal tilted orientation.
US11260890B2 Adjustable span tine pallet jack
A pallet jack includes a base and a pair of tines extending from the base. The pair of tines including a first tine and a second tine. A load wheel supports an outer end of each of the pair of tines. Each load wheel is configured to move toward and away from the respective tine to raise the tine off a floor on which the load wheel is supported. The first tine including a support surface configured to selectively be a lowermost surface of the tine to facilitate lateral displacement of the first tine.
US11260889B2 Cart and wheel connecting structure
A cart comprises a body structure and at least one wheel connecting structure. The body structure comprises a support shaft, a first frame member and a second frame member. Both the first and second frame members are disposed on the support shaft. The wheel connecting structure is disposed on one end of the support shaft and comprises a driving assembly, a rotating assembly, a linking assembly, and an energy assembly. The driving assembly is connected to the first frame member. One end of the rotating assembly is disposed in correspondence with the one end of the support shaft, and the other end of the rotating assembly is mounted on a wheel member. The linking assembly is disposed between the driving assembly and the rotating assembly. The linking assembly comprises a pushing unit, which is pivotally connected to the rotating assembly. The energy assembly is connected to the linking assembly.
US11260888B2 Method and system for health assessment of a track circuit and/or of a track section
A method and system for health assessment of a track circuit and/or of a track section, the track circuit being configured for detecting the presence of a vehicle on the track section between a transmitting end and a receiving end of the track circuit. The method, implemented by an electronic device, comprises obtaining, from a sensor device placed near the receiving end, samples of an electrical parameter of an electric signal transmitted between the transmitting end and the receiving end of the track section, forming a temporal series of received samples, applying an automatic clustering algorithm to separate the received samples in a predetermined number of clusters, selecting one of the clusters and determining, for the selected cluster, a first peak value of the received samples classified within the selected cluster, and calculating a track circuit health indicator depending on the first peak value determined for the selected cluster.
US11260885B2 Overhead transport and route management system
An overhead transport system includes a suspended railway and a motorized carrier configured to travel along the suspended railway. The motorized carrier includes a motorized trolley configured to move the motorized carrier along the suspended railway, chassis/beam configured to carry an object below the motorized trolley, and a bumper and deflection system configured to prevent the object from contacting another object.
US11260882B2 Method and system for context-aware decision making of an autonomous agent
A system for context-aware decision making of an autonomous agent includes a computing system having a context selector and a map. A method for context-aware decision making of an autonomous agent includes receiving a set of inputs, determining a context associated with an autonomous agent based on the set of inputs, and optionally any or all of: labeling a map; selecting a learning module (context-specific learning module) based on the context; defining an action space based on the learning module; selecting an action from the action space; planning a trajectory based on the action S260; and/or any other suitable processes.
US11260880B2 Map-less and localization-less lane following method for autonomous driving of autonomous driving vehicles on highway
In one embodiment, instead of using map data, a relative coordinate system is utilized to assist perception of the driving environment surrounding an ADV for some driving situations. One of such driving situations is driving on a highway. Typically, a highway has fewer intersections and exits. The relative coordinate system is utilized based on the relative lane configuration and relative obstacle information to control the ADV to simply follow the lane and avoid potential collision with any obstacles discovered within the road, without having to use map data. Once the relative lane configuration and obstacle information have been determined, regular path and speed planning and optimization can be performed to generate a trajectory to drive the ADV. Such a perception system is referred to as a relative perception system based on a relative coordinate system.
US11260879B2 Vehicle and method for controlling the same
A vehicle is provided that includes a bio-signal sensor configured to measure a bio-signal of a user and a feedback device configured to interact with the bio-signal of the user. A controller determines a current emotional state of the user based on the bio-signal and adjusts an output signal of the feedback device based on the current emotional state. The output signal leads to a target emotional state in which the degree of excitability is a reduced emotional state.
US11260877B2 Method for selecting a driving profile of a motor vehicle, driver assistance system and motor vehicle
A method for selecting a driving profile of a motor vehicle, a driver assistance system therefor and a motor vehicle equipped therewith is disclosed. In the method and based on an operating action by a driver, a deviation between the number of predetermined driving profiles currently desired by the driver and that previously used is recognized. After the deviation has been recognized, a query is output to the driver as to whether the deviation should be taught by the driver assistance system for the current situation. After the query has been confirmed by the driver, the driver assistance system is accordingly adapted for the current situation in at least one parameter influencing the selection of the driving profile to be used such that the deviation in the automatic selection of the driving profile to be used in future situations that correspond to the current situation is taken into account.
US11260874B2 Driver assistance device that can be mounted on a vehicle
An acquisition unit acquires at least one of first information and second information. A notification unit provides warning information to the driver, the warning information being generated based on at least one of the first information and the second information acquired and indicating a possibility of an increase in an insurance premium of an insurance applied to the driver. An reception unit receives acceptance of the provided warning information from the driver. A processor determines to transmit the acceptance by the driver of the possibility of an increase in the insurance premium to an insurance company server when the acceptance is received and determines to transmit at least one of the first information and the second information to the insurance company server when acceptance is not received.
US11260872B2 System and method for utilizing a temporal recurrent network for online action detection
A system and method for utilizing a temporal recurrent network for online action detection that include receiving image data that is based on at least one image captured by a vehicle camera system. The system and method also include analyzing the image data to determine a plurality of image frames and outputting at least one goal-oriented action as determined during a current image frame. The system and method further include controlling a vehicle to be autonomously driven based on a naturalistic driving behavior data set that includes the at least one goal-oriented action.
US11260871B2 Road information detection device, driving assistance device, road information detection system, road information detection method, driving control method and program
A road information detection device includes a curve-starting-position identification part configured to identify the starting position of a transition curve according to a road structure upon detecting an attached structure on a road. It further includes an image information capture part configured to capture an image, an attached-structure detection part configured to detect the identification of an attached structure reflected in the image, and a storage media configured to store the position of an attached structure. The curve-starting-position identification part may identify the starting position based on the detected identification of an attached structure, the stored position of an attached structure, and a distance from the attached structure to the starting position of a transition curve.
US11260870B2 Determining a maximum frictional-connection coefficient
A tire (100) rolls on a surface (105). A method (600) for providing maximum traction coefficient between the tire (100) and the surface (105) include steps for detecting a momentary slip of the tire (100) on the surface (105); detecting a momentary traction coefficient; forming a tuple (410, 510) from the slip and the current traction coefficient; choosing a characteristic curve (205, 305) from a number of predetermined characteristic curves (205, 305) on the basis of the tuple (410, 510), whereby each characteristic curve (205, 305) describes a traction behavior of the tire (100) or a corresponding characteristic pitch; determining the maximum traction coefficient on the basis of the selected characteristic curves (205, 305); and thus providing the maximum traction coefficient.
US11260866B2 Vehicle control device, vehicle control method, and storage medium
A vehicle control device includes an action controller that is configured to control an action of a vehicle, in which, in a case where there is another vehicle traveling on a second road adjacent to a first road on which the vehicle is traveling, and the vehicle is controlled to overtake another vehicle, the action controller is configured to accelerate the vehicle, causes the vehicle to show an intention to enter the second road when the vehicle is located a predetermined distance or more in front of another vehicle in an advancing direction of the vehicle after the vehicle is accelerated, and decelerates the vehicle while maintaining the vehicle in a state in which the vehicle is located in front of another vehicle at a timing according to the entry intention.
US11260862B2 Method for controlling engine clutch of vehicle
A method for controlling an engine clutch of an electrified vehicle is provided to easily engage and disengage an engine clutch by applying a launch engagement control method that utilizes power from both of an engine and a motor in accordance with the variation of the number of revolutions per hour of the engine and the usage rate of electrical energy by a motor to engage the engine clutch in a terrain mode and by applying a control method that disengages an engine clutch early in accordance with the number of revolutions per hour of the engine and the shaft torque of the engine clutch in the terrain mode.
US11260861B2 Method, device and computer-readable storage medium with instructions for determining the lateral position of a vehicle relative to the lanes on a roadway
A method, a device and a computer-readable storage medium with instructions for determining the lateral position of a vehicle relative to the lanes on a roadway. The device has an image processing unit for detecting roadway markings as well as a positioning unit for determining an initial position for the vehicle. An evaluation unit is set up to determine that the detected roadway markings are insufficient for detecting a lateral position of the vehicle by comparing the detected roadway markings with roadway marking information from a lane geometry map for the initial position determined for the vehicle. In this case, the evaluation unit identifies an approximate lateral position of the vehicle while taking into consideration information from the lane geometric map.
US11260859B2 Vehicle control system, vehicle control method, and storage medium
A vehicle control system includes a first steering controller that executes first steering control for controlling a steering device such that a traveling lane is maintained, and a second steering controller that executes second steering control that is activated during execution of the first steering control. If a command value given to the steering device in the first steering control has continued to deviate either left or right in a case that the second steering control starts, the second steering controller executes the second steering control by reflecting the command value given in the first steering control.
US11260858B2 Prediction device, prediction method, and storage medium
A prediction device includes a camera configured to repeatedly image a region ahead of a vehicle, an extractor configured to extract a region including other vehicles from each of a plurality of images repeatedly captured by the camera, and a predictor configured to predict that a traffic jam will occur in a road on which there is the vehicle on the basis of a change in the region extracted from each of the plurality of images by the extractor between the images.
US11260857B2 Polyline contour representations for autonomous vehicles
Aspects of the disclosure relate to controlling a vehicle having an autonomous driving mode or an autonomous vehicle. For instance, a polygon representative of the shape and location of a first object may be received. A polyline contour representation of a portion of a polygon representative of the shape and location of a second object may be received. The polyline contour representation may be in half-plane coordinates and including a plurality of vertices and line segments. Coordinates of the polygon representative of the first object may be converted to the half-plane coordinate system. A collision location between the polyline contour representation and the polygon representative of the first object may be determined using the converted coordinates. The autonomous vehicle may be controlled in the autonomous driving mode to avoid a collision based on the collision location.
US11260853B2 Collision avoidance device and collision avoidance method for vehicle
A collision avoidance device for a vehicle is provided. The collision avoidance device includes an object sensing unit for sensing an object, an attribute acquisition unit for using a sensing result from the object sensing unit to acquire an attribute of an oncoming vehicle, and a collision avoidance execution unit for executing at least one of a notification of a possibility of collision and a collision avoidance operation, if it is determined, based on the attribute acquired by the attribute acquisition unit, that the oncoming vehicle crosses a center line.
US11260850B2 Method for influencing driving dynamics of a vehicle, and driving dynamics controller
A method for influencing driving dynamics of a vehicle, in which the driving dynamics are influenced as a function of parameters allocated to a selected driving dynamics mode when the driving dynamics mode is activated, and the driving dynamics are influenced as a function of road state information representing a road state in the region of the vehicle when an automatic mode is activated.
US11260844B2 Managing engine firing fraction changes
Methods and controllers for coordinating firing fraction transitions that occur in conjunction with transmission shifts are described. In one aspect, an engine controller transmits a do-not-shift instruction to a transmission controller based at least in part on a determination that a particular type of firing fraction transition is desired. The firing fraction transition is then implemented using a skip fire transition protocol. In this manner, the transmission is affirmatively prevented from shifting during the firing fraction transition. The described approaches are well suited for use in connection with transitions to DCCO or DFCO operation.
US11260830B2 Reduced arc windshield wiper system for a vehicle
A windshield wiper system (100) includes a pivoting wiper arm (110); a wiper blade (120) for wiping a surface (102); and a connector assembly (128) coupling the pivoting wiper arm (110) to the wiper blade (120), the connector assembly (128) comprising a gear drive (130) including at least one drive gear (132) and at least one positioning cog (136), wherein the gear drive (130) rotates the wiper blade (120) based on an angular position of the pivoting wiper arm (110) such that an arc of a motion path (320) of the wiper blade (120) is reduced.
US11260828B2 Method and apparatus for controlling vehicle, and vehicle
A method for controlling a vehicle is applied to an in-vehicle terminal, includes: obtaining current position information of a vehicle and a preset electronic fence, determining a travel direction according to the current position information and the preset electronic fence; when determining that the vehicle travels from the inside of the preset electronic fence to the outside of the preset electronic fence, determining a current position state of the vehicle according to the current position information, where the position state represents a relative position of the vehicle and the preset electronic fence; determining whether the current position state is the same as a previous position state of the vehicle; and when the current position state is different from the previous position state, performing one or two of outputting warning information and sending a key shielding signal, to enable a key controller to shield a key control signal of the vehicle.
US11260825B2 Locking and unlocking system
A locking and unlocking system includes a controller. The controller is configured to acquire a state of locking and unlocking of a vehicle that is locked and unlocked based on locking and unlocking instruction information acquired from a portable terminal, and send a notification to a first device associated with the vehicle, when the vehicle is not locked during a period of time from when the vehicle is unlocked based on the locking and unlocking instruction information acquired from the portable terminal until a first timing.
US11260822B2 Side airbag device
A side airbag device includes: a side airbag in a folded state; a gas generator that includes an attachment portion to be attached to a vehicle, and that is configured to generate inflation gas to be supplied to the side airbag; a wrapping sheet that covers peripheries of the side airbag and the gas generator, and that is breakable when the side airbag is deployed and inflated; and a wire harness that includes a connection end portion electrically connected to the gas generator, and that is led out to an outer portion of the wrapping sheet. The wire harness is provided with a first locking portion, and the wrapping sheet is provided with a second locking portion that is locked to the first locking portion.
US11260821B2 Airbag mounting tab assembly
An apparatus for helping to protect an occupant of a vehicle includes a curtain airbag inflatable from a stored condition to a deployed condition in which the curtain airbag is positioned between a side structure of the vehicle and the vehicle occupant. The curtain airbag comprises a mounting tab comprising overlying layers of airbag material that define a pocket and through each of which a mounting tab aperture extends. A bracket comprises a plate with a bracket aperture extending therethrough. The bracket is positioned in the pocket so that the bracket aperture is aligned with the mounting tab apertures. A fastener has a portion extending though the mounting tab apertures and the bracket aperture. The fastener blocks the bracket from removal from the pocket.
US11260819B2 Airbag apparatus
An airbag apparatus equipped in a vehicle seat having a seat cushion that forms a seating surface and a seat back that forms a backrest includes: an inflator that generates inflation gas; and an airbag housed within at least the seat back and deployed by inflation gas released from the inflator. The airbag includes a pair of left and right side chambers that deploy towards the front from a side portion of the seat back and an upper chamber that deploys above the head of a passenger. The airbag is rolled in a direction that intersects the longitudinal direction from a flat unfolded state prior to being housed or folded to be compressed into a long bar shape. A folded portion is formed by folding at least a location corresponding to the upper chamber of the long bar shaped airbag to house the folded portion above the seat back.
US11260815B2 Protection of a vehicle occupant
The present disclosure relates to a method performed by an occupant protection system of a vehicle for supporting protection of a vehicle occupant in the event of an ongoing or imminent collision. The occupant protection system comprises an airbag panel arrangement arranged in connection with a dashboard of the vehicle, which airbag panel arrangement comprises an inflatable airbag adapted to upon deployment protect lower body parts of a vehicle occupant seated in a vehicle seat facing the dashboard. The occupant protection system determines a distance in a predeterminable direction between the airbag panel arrangement or the dashboard and the vehicle seat or an occupant seated in the vehicle seat; determines that the distance exceeds a predeterminable maximum threshold value; determines that one or more conditions for deployment of the airbag is fulfilled; and displaces the airbag panel arrangement outwardly from the dashboard by means of a panel displacing system.
US11260814B1 Bug screen and method of mounting
A bug screen for mounting to a grille of a vehicle comprises a membrane disposed in a frame. At least one slot is disposed on the frame, and at least one platform is disposed on the grille. At least one extension is disposed on the at least one platform. A leg is included in the at least one extension. The leg projects perpendicularly from the at least one platform and has an end opposite to the at least one platform. A barb is disposed on the end of the leg. A sloping surface is disposed on the barb, and the sloping surface passes through the at least one slot on the frame to mount the bug screen to the grille.
US11260813B1 Vehicle dent protection system
The vehicle dent protection system attaches to and protects a vehicle from dents while said vehicle is parked. A plurality of instantiations of the vehicle dent protection system are attached to the vehicle such that the plurality of instantiations form a protected space around the vehicle. The vehicle dent protection system is a sacrificial structure that receives and dissipates an impact before the impact can damage the vehicle. The vehicle dent protection system includes a plurality of telescopic structures, a plurality of pivot structures, a sacrificial module, and a frame mount. The plurality of pivot structures interconnect the plurality of telescopic structures such that the plurality of telescopic structures can rotate. The plurality of telescopic structures attach the sacrificial module to the frame mount such that the position of the sacrificial structure relative to the frame mount is adjustable.
US11260812B2 Apparatus and method for enabling storing of a user input vehicle setting
An apparatus (101) for enabling storing of settings of a vehicle (201), a system, a vehicle (201), a method (300, 400, 500, 600), a computer program (105) and a non-transitory computer-readable storage medium (108) are disclosed. The apparatus (101) comprises a processing means and a memory means for storing at least one setting of the vehicle (201) for at least one user. The apparatus (101) is configured to determine that access into a vehicle (201) has been granted in dependence on a first primary identifier having been received from a first primary electronic device (218A) and determine that a first secondary identifier corresponding to a first user of the vehicle (201) has been received from a first secondary electronic device (221). The apparatus (101) is also configured to, in dependence on determining that the first secondary identifier has been received from the first secondary electronic device (221) and that access into the vehicle has been granted in dependence on the first primary identifier having been received from the first primary electronic device (218A), enable storing of a setting of the vehicle (201) for the first user.
US11260807B2 Vehicle door protection device and method of use
A vehicle door protection device includes an exterior casing composed of a material and extending from a top end to a bottom end, the exterior casing having an elastic opening at the bottom end; and a pocket sewn into a back side of the exterior casing; a magnetic strip to secure within the pocket, the magnetic strip having a flexible strip; and one or more magnets secured to the flexible strip; the magnetic strip provides for securement of the vehicle door protection device to a vehicle door; a padding to removably secure within the exterior casing via the elastic opening; the padding provides protection to the door from damage.
US11260805B2 Apparatus and method for monitoring a vehicle camera system
An apparatus for monitoring a vehicle camera system. The vehicle camera system includes at least one camera to capture images of a field of view at a side of the vehicle and a display unit for visualizing the captured images to a driver of the vehicle. The apparatus includes a control unit adapted to control the display unit to display a graphical indicator, the displayed graphical indicator changes sequentially in a default way to allow the driver to visually detect a malfunctioning of the vehicle camera system based on a deviation from the default way of the sequentially changing graphical indicator.
US11260803B2 Audio system for a utility vehicle
An all-terrain or utility vehicle includes an audio system having at least one speaker. The at least one speaker is positioned at a forward portion of the operator area and is supported by a body panel. More particularly, the body panel may be configured to receive at least a portion of the speaker as well as at least a portion of an upper frame assembly. In this way, the speaker is positioned to direct sound towards the rider, is generally concealed from a front view of the vehicle, and is positioned within available space on the vehicle above at least a portion of the door.
US11260802B2 Display unit for a vehicle
An entertainment system including a removable seat-back display unit and a docking station. The seat-back display unit can include a rotating latch butterfly release mechanism that prevents unauthorized release of the display unit from the docking station. The system can include a three-point attachment system that provides additional protection against accidental detachment of the display unit, and provide safety in the event of partial dislodging. The system can include a current control pin system that ensures that current is not provided from the docking station to the display unit until the respective connectors have been properly engaged. The system can further include a floating pin connector dock that can allow for installation of the display unit even when the connectors of the display unit and docking station become misaligned. The system can also include a heat dissipation system that employs the docking station to share the heat dissipation load with the display unit.
US11260801B2 Vehicle roof rail assembly
A vehicle roof rail assembly includes a roof rail and a bracket. The roof rail is fixedly attached to the roof of a vehicle. The roof rail has a recessed portion with fastener receiving portions located therein. The bracket has an attachment flange and an accessory supporting flange rigidly fixedly attached to the attachment flange. The attachment flange is removably attached to the roof rail via first fastener members that are removably fixed to the fastener receiving portions. The attachment flange overlays a section of the recessed portion the roof rail. The accessory supporting flange has an opening defined therein for attachment of roof accessory retaining elements.
US11260797B2 Retractable vehicle step assemblies and methods
A retractable vehicle step assembly includes a drive shaft having a spline and a step coupled to the drive shaft through a step linkage system. The step is moveable between an extended position and a retracted position. The step linkage system includes a first step linkage defining a spline engagement opening for engagement with the spline of the drive shaft and a fastener. The fastener is adjustably coupled to the first step linkage so as to clamp the spline engagement opening of the first step linkage around the drive shaft. Upon loosening the fastener, the first step linkage is disengageable from the drive shaft and the step is moveable from the extended position to the retracted position regardless of rotation of the drive shaft.
US11260796B2 Detachable workpiece support apparatus for a tailgate step
A workpiece support is provided for a pickup truck tailgate. The tailgate includes a retractable step including a pair of step support members. The attachment brackets include a workpiece support bar and a riser that are attached to the step support members and to each other at a right angle. The workpiece support bar and riser may be fixedly attached to each other or attached by a pivot connector. Detachable connectors are provided to connect a workpiece support bar and riser detachably to the step support members.
US11260795B2 Display inside mirror of vehicle
A display inside mirror includes a housing configured to be secured to a windshield glass, the housing having an opening formed therein, a mirror part disposed in the opening, a display unit disposed so as to face the mirror part, a control unit disposed adjacent to the display unit so as to control the transmission of a display image, a tilting lever disposed at one end of the housing so as to tilt the mirror part, and a switch unit disposed at the tilting lever so as to allow the power from the control unit to be selectively applied to the display unit.
US11260794B2 Periphery monitoring device
A peripheral monitoring device according to one embodiment includes an acquirer configured to acquire a first rear image of a vehicle at first timing, the vehicle including a first coupler device which couples a towed vehicle; and an image processing unit configured to superimpose first identification information on the first rear image at second timing being after the first timing, the first identification information representing a position of the first coupler device at the second timing, and to display, on a display screen, the first rear image on which the first identification information has been superimposed, the display screen configured to be installed in the vehicle.
US11260793B2 Construction machine and method of controlling construction machine
A construction machine includes an image capturing device configured to capture an image of the surroundings, an image display part mounted in an operator's cab and configured to display a menu screen showing an operating condition and various settings, or the captured image captured with the image capturing device, an operation part including a menu switch to cause the menu screen to be displayed on the image display part, and a detector configured to detect whether a work element is enabled or disabled. The image display part is configured to display a warning in response to the menu switch being operated while the work element is enabled.
US11260792B1 Method of controlling tone of electric vehicle based on motor vibration in deceleration or regenerative braking conditions
A method of controlling a tone of an electric vehicle (EV) includes calculating order components from vibration signals of a rotating motor of the EV, extracting an Nth order component having a determination coefficient R2 which represents linearity with respect to an output torque of the motor and is greater than or equal to a predetermined value, converting an RPM of the motor into a frequency and calculating an order frequency, arranging the order components by applying a vibration level of the Nth order component to a level of the order frequency to be output and setting an EV mode tone, and in a deceleration of the EV, determining a deceleration condition and applying the vibration level of the Nth order component to level control of the order frequency.
US11260787B2 Device and method for securing cargo
A device and method for securing cargo to vertical logistics posts on a side of a transportation vehicle. The device comprises a rail with a plurality of slots, an adjustable slide for adjusting the overall horizontal length of the device to fit between irregularly spaced gaps of parallel vertical logistics posts, and clips that are inserted and removably retained in corresponding receiving spaces of vertical logistics posts. Cargo is secured to the device through the slots on the rail. The device provides ease of relocation and adjustment for irregular gaps between vertical logistics posts.
US11260783B2 Overmold decorative floor mat emblem
A floor mat including an elastomeric mat and an emblem with a base and a shell. The base has a portion supporting the shell and a peripheral flange portion surrounding the supporting portion and forming a hidden portion within the floor mat and having apertures. The shell overlays the supporting portion and forms a visible portion of the emblem on only one side of the floor mat. The apertures are essentially filled with elastomer to fix the emblem into the desired location on the floor mat. Also, the emblem and a method for making a floor mat.
US11260782B1 Bracket assembly for a vehicle
A vehicle bracket assembly includes first and second platforms each including a body and connectors that extend from each of the bodies. A central base is disposed between the first and second platforms and are coupled to the first and second platforms via the connectors. First and second connecting legs are coupled to the body of each of the first and second platforms, respectively. A first attachment base is coupled to the first platform via the first connecting legs. A second attachment base includes a locating tab. The second attachment base is coupled to the second platform via the second connecting legs.
US11260781B2 Suspension arrangement for a seat and method of producing an elongate suspension member for a suspension arrangement for a seat
The present invention relates to a suspension arrangement (20, 120) for a seat comprising a plurality of elongate suspension members (21, 22, 121, 122) of a glass fibre filled plastic. Each elongate suspension member (21, 22, 121, 122) of the plurality of elongate suspension members includes in a longitudinal direction thereof a first end (23, 25, 123, 125) and an opposing second end (24, 26, 124, 126). The elongate suspension member (21, 22, 121, 122) has a meandered shape in the longitudinal direction. The present invention relates furthermore to a method for producing an elongate suspension member (21, 22, 121, 122).
US11260778B2 Child safety seat
A child safety seat includes a seat portion, a backrest assembly connected with the seat portion and including a first and a second portion slidably connected with each other and a third portion slidably connected with the second portion, and a backrest adjusting system carried with the backrest assembly and configured to provide a first stage of height adjustment where the first and second portions are locked with each other and the third portion is movable relative to the first and second portions for adjustment, and a second stage of height adjustment where the second portion is locked with the third portion and unlocked from the first portion so that the second portion and the third portion are movable in unison relative to the first portion for adjustment.
US11260777B2 Recliner heart for seat recliner assembly
A recliner heart includes first, second and third locking plates and a pawl. The first locking plate defines a recess. The second locking plate includes a first inner diametrical surface having first teeth formed thereon. The third locking plate is disposed between the first and second locking plates and includes a second inner diametrical surface and an outer diametrical surface. The second inner diametrical surface has a notch formed therein. The outer diametrical surface has second teeth formed thereon. Some of the second teeth are meshingly engaged with some of the first teeth. The pawl is slidably disposed in the recess between a secure position in which the pawl is engaged with the notch of the third locking plate and a release position in which the pawl is disengaged from the notch of the third locking plate.
US11260776B1 Manual and powered actuation of seating assembly
A vehicle seating assembly is provided that includes a seat frame movable between a sitting position and a standing position and coupled to a pivot bracket, a cross member extending through the pivot bracket and defining an axis of rotation, and a gear assembly coupled to the pivot bracket. The gear assembly includes a sector bracket rotationally coupled to the cross member, and a pinion gear operable to rotate along the sector bracket from a first position to a second position, thereby moving the seat frame between a sitting position and a standing position. The vehicle seating assembly further includes a locking disk assembly coupled to the pivot bracket such that if the locking disk assembly is in a disengaged position relative to the sector bracket, then the frame is rotatable about the axis of rotation defined by the cross member.
US11260772B2 System, method and apparatus that detect and remedy battery health conditions
An apparatus and method that detects and remedies a battery health condition are provided. The method includes receiving data including one or more of vehicle sensor information, dealer information and vehicle characteristic information, analyzing the received data to determine whether one or more battery health alerts are required, and outputting or transmitting the one or more determined battery health alerts.
US11260771B2 Vehicle power supply system
A vehicle power supply system is provided. The system includes a first power line connected by a first inverter and a first battery, a second power line connected by a second inverter and a second battery, a voltage converter, and a charging and discharging control device operating the inverters and the voltage converter. The control device charges the second battery with second regenerative electric power that is power supplied from the second inverter to the second power line in a case where a second SOC is equal to or less than the second regeneration permission upper limit during regenerative deceleration, and prohibits the second battery from being charged and supplies at least a portion of the second regenerative electric power to the first battery through the voltage converter and the first power line when the second SOC is larger than the second regeneration permission upper limit.
US11260765B2 Autonomous travel work machine and charging station
The lawn mower has at least a first structure in which a pair of power receiving terminals are separately disposed in the vehicle body cover and the vehicle body that are different parts from among a plurality of parts constituting the lawn mower, or a second structure in which the power receiving terminal, which is one of the pair of power receiving terminals, has a downward-facing contact surface that comes into contact with the charging station.
US11260759B2 Electric vehicle and method for charging between electric vehicles
An electric vehicle that includes a battery pack, a direct current socket, and a controller and a charging method for charging between electric vehicles, where in a process in which the direct current socket is coupled to an alternating current socket of another electric vehicle using a charge/discharge cable, the battery pack is controlled based on a charging request of the other electric vehicle to charge the other electric vehicle. Hence, charging between electric vehicles can be conveniently implemented.
US11260755B2 Battery management apparatus and method
The figures illustrate an apparatus (10-1, 10-2, 10-3) for a vehicle (100) comprising: first energy storage means (12) for storing electrical energy; second energy storage means (14) for storing electrical energy; and control means (16) arranged to transfer electrical energy from the second energy storage means (14) to the first energy storage means (12) when the level of electrical energy stored in the first energy storage means (12) is below a first electrical energy threshold level and the level of electrical energy stored in the second energy storage means (14) is above a second electrical energy threshold level.
US11260754B2 Electric vehicle control device that controls electric vehicle equipped with chargeable and dischargeable battery and electric motor that drives driving wheel by being supplied with electric power charged in battery, and electric vehicle
This control device for an electric vehicle is provided with: a discharge control unit which, when the electric vehicle has been turned off, if the SOC of the battery is within a prescribed range in which the battery is prone to deteriorate, performs control for discharging the battery until the SOC has left the prescribed range; a travelable distance calculation unit which calculates the travelable distance of the electric vehicle using the SOC and a travel coefficient; and a travel coefficient correction unit which, before and after performing control for discharging the battery is performed by the discharge control unit, corrects the travel coefficient such that the travelable distance calculated by the travelable distance calculation unit is reduced.
US11260746B2 Fuel tank assembly for a vehicle
A vehicle has a frame defining a cockpit area. The frame has a roll cage disposed over the cockpit area. The vehicle has driver and passenger seats, an engine connected to the frame, and a plurality of ground engaging members operatively connected to the frame, at least one ground engaging member of the plurality of ground engaging members being operatively connected to the engine. The vehicle also has a fuel tank assembly including a fuel tank connected to the frame. The fuel tank is forward of the seats and at least a portion of the fuel tank is disposed under the roll cage.
US11260745B2 Filler and/or charger flap liner having a seal arrangement
A filler and/or charger flap liner (3) is provided with a seal arrangement. The filler and/or charger flap liner (3) is to be arranged in an opening (6) of an outer side part (4) and in an opening (7) of an outer wheel arch (5). The filler and/or charger flap liner (3) is to be arranged with a first bearing element (8) on an edge of the opening (6) of the outer side part (4) and is to be arranged with a second bearing element (9) on an edge of the opening (7) of the outer wheel arch (5). An at least partially circumferential sealing element (10) is arranged radially outside the openings (6, 7) of the outer side part (4) and the outer wheel arch (5).
US11260739B2 Energy harvesting clutch control assembly, valve assembly, and electrically actuated clutch
A clutch assembly includes a clutch mechanism and an energy harvesting device. The clutch mechanism includes an input member, an output member, and an actuating mechanism to govern selective torque transmission from the input member to the output member. The actuating mechanism is powered by electrical current. The energy harvesting device is electrically connected to the actuating mechanism, and the energy harvesting device is configured to scavenge available energy to generate the electrical current that powers the actuating mechanism.
US11260738B2 HSG cooling control apparatus for hybrid vehicle, HSG cooling control method thereof, and hybrid vehicle including HSG cooling control apparatus
A hybrid starter and generator (HSG) cooling control apparatus for a hybrid vehicle, and an HSG cooling control method thereof, the apparatus includes a receiver configured to receive driving information of an engine and a hybrid starter and generator (HSG), a cooling unit configured to cool the HSG, and a controller configured to control the cooling unit, wherein the controller determines whether the HSG is in an idle charging mode based on driving information of the engine and the HSG, determines whether the temperature of the HSG is greater than a first cooling-required temperature when the HSG is in the idle charging mode, and controls the cooling unit to be turned on when the temperature of the HSG is greater than the first cooling-required temperature.
US11260731B2 Vehicle door assembly
A vehicle door assembly includes an inner door panel that partially defines a cavity therein, a door handle assembly, a main reinforcing bracket, a first reinforcing bracket and a vibration absorbing member. The first reinforcing bracket has an upper end fixedly attached to the main reinforcing bracket and to a rearward area of the inner door panel within the cavity below the door handle assembly. The vibration absorbing member has an outboard surface, an inboard surface and a main projection that extends forward from the main body. The main projection is fixed to the first reinforcing bracket such that the main body is rearward of the first reinforcing bracket. The outboard surface is shaped and dimensioned to correspond to the overall shape of the inboard portion of the door handle assembly.
US11260727B2 Vehicle, refrigerator for vehicle, and controlling method for refrigerator for vehicle
A vehicle, a refrigerator for a vehicle, and a method for controlling a refrigerator for a vehicle are provided. The method for controlling the refrigerator for the vehicle includes turning on a switch of the refrigerator for the vehicle, measuring a temperature of an interior of the refrigerator for the vehicle a first time, measuring a temperature of the interior of the refrigerator for the vehicle again a second time after a predetermined time has elapsed from the first time, determining a temperature change of the interior of the refrigerator from the first time to the second time, and operating the refrigerator for the vehicle in a quench mode in which the temperature in the interior of the refrigerator is rapidly lowered, unlike a normal mode, if the temperature change in the interior of the refrigerator is in a positive direction.
US11260726B2 Gravity independent pressure relief valve
A pressure relief valve is provided that includes a housing and a flap. The housing includes a plurality of receptacle members with openings therebetween, and the flap is configured to be accepted by the housing and to contact the receptacle members in a closed position. Further, the flap covers the openings and inhibits airflow through the openings in a closed position, and the flap is biasable to allow airflow through the openings in an open position.
US11260724B2 Vehicular air conditioning system and method for controlling the same
A vehicular air conditioning system includes: a heat pump side refrigerant circulation line including a compressor, a water-cooled heat exchanger, a heat pump mode expansion valve, an air-cooled heat exchanger, an air conditioner mode expansion valve and an evaporator, the heat pump side refrigerant circulation line configured to generate cold energy in the evaporator in an air conditioner mode and to generate heat in the water-cooled heat exchanger in a heat pump mode, the air-cooled heat exchanger configured to allow a refrigerant to exchange heat with an ambient air in the air conditioner mode and the heat pump mode; and a heat exchange air switching part configured to switch the type of the air heat-exchanged in the air-cooled heat exchanger depending on the air conditioner mode or the heat pump mode.
US11260722B2 System and methods for reducing air pressure in a cabin of a vehicle to assist in door closure
System, methods, and other embodiments described herein relate to assisting in closing a door of a vehicle by leveraging a Heating, Ventilation and Air-conditioning (HVAC) system in the vehicle. In one embodiment, a method includes detecting a position of at least one vehicle door, and when the position of the at least one vehicle door is an open position, determining whether to activate the HVAC system to reduce air pressure in a cabin of the vehicle. The method includes, in response to determining to activate the HVAC system, pumping air out of the cabin such that at least some of any increased air pressure caused by a vehicle door closure is removed from the cabin. The method includes, when the position of the at least one vehicle door has changed from the open position to a closed position, deactivating the HVAC system to stop pumping air out from the cabin.
US11260721B2 Motor vehicle
A motor vehicle is provided in which cold air is prevented from flowing forwards from the rear region to the front seats when travelling with an open top. At least one air outlet opening or air outlet nozzle is formed at a rear end of the center console, through which air outlet opening or air outlet nozzle warm air can flow out upwards and/or forwards between the two backrests of the two front seats. Further air outlet openings are provided in the two opposite B body pillars, through which air outlet openings warm air can flow out forwards in the direction of the backrests of the front seats and/or in the transverse direction of the vehicle into the rear region.
US11260719B2 Battery cooling system including a cooling water circulation circuit
A battery cooling system includes a cooling water circulation circuit for circulating cooling water for cooling the battery, a first heat exchanger for exchanging heat between air and cooling water, a second heat exchanger for exchanging heat between the low-pressure refrigerant of the refrigeration cycle circuit and cooling water, and an ion exchanger for removing impurity ions contained in the cooling water. The first heat exchanger and the second heat exchanger are arranged in series in the cooling water circulation circuit. The ion exchanger is disposed on the downstream side of the second heat exchanger in the cooling water circulation circuit.
US11260715B2 Chassis component
The invention relates to a chassis component having a base face which extends in a base face plane and an aperture for the introduction of a fixing means and two retention elements which are arranged at opposite sides of the aperture for retaining an eccentric element, wherein the retention elements are formed integrally and in a materially engaging manner from the base face of the chassis component, wherein the retention elements are displaced out of the base face by mechanical processing. The chassis component affords a simple ability to be produced and an increased service life during operation.
US11260708B2 Trailer-mounted mock landing gear
An example apparatus is configured to couple to a trailer and a tow vehicle. The apparatus includes a frame; one or more clamps mounted to the frame and configured to couple the frame to an underplate of the trailer; and a shaft having a first end rotatably coupled to the frame and a second end configured to couple to at least one replicated element of a towed vehicle. The at least one replicated element is configured to engage the tow vehicle.
US11260703B2 Pneumatic tire with reinforcement material
A pneumatic tire with a reinforcement material includes: a tread that comes in contact with a road surface; side walls that extend and form shoulders and inner liners at both sides of the tread; a carcass that is integrally attached to the tread and the inner sides of the side walls and forms a turn-up head at both ends of the side walls; a belt layer that is layered on the tread of the carcass; and a bead that includes a bead core inserted in a wheel inside the turn-up head, a bead filler inserted in a side of the tread of the bead core, and a reinforcement material inserted in an interface of the turn-up head.
US11260701B2 Pneumatic tire
A pneumatic tire has paired bead portions, paired sidewall portions, a tread portion, a plurality of lug grooves extending from a shoulder area of the tread portion to reach a buttress area of the sidewall portion, and a block defined by the plurality of lug grooves. The block includes a shoulder block provided in the shoulder area, and a buttress block provided in the buttress area. The buttress area is provided with an annular rib annularly extending along a tire circumferential direction. The lug grooves are comparted into an outside lug groove positioned in an outer side of the annular rib, and an inside lug groove positioned in an inner side of the annular rib. A widened portion is provided in at least part of the plurality of lug grooves so as to enlarge a width of the annular rib.
US11260697B2 Tire with tread features having offset protrusions
A shear-controlled tire tread includes a plurality of narrow channels disposed generally perpendicular to a rolling direction. Each narrow channel includes a heel side, a toe side, and a valley connecting the heel side and the toe side, and a first plurality of ridges disposed on a heel side and a second plurality of ridges disposed on a toe side. The first plurality of ridges disposed on a heel side and the second plurality of ridges disposed on a toe side are offset and form interacting friction surfaces when a heel side of collapses toward a toe side or a toe side collapses toward a heel side.
US11260695B2 Reinforced rubber spoke for a tire
A spoke (100) for a wheel (10) attaching an outer tread (200) to a hub (20), the spoke having a first (142) and second (144) spoke elements joined by a joint body (130) comprised of an elastomer connecting the first spoke element to a second spoke element.
US11260692B2 Portal-axle of low floor rail vehicles and rail-and-tram vehicles
A portal-axle of bogies for light rail vehicles, such as for example trams or light rail metros with street running, is described, the light rail vehicles being characterized by a floor, i.e. a walking surface, lowered with respect to the rails. The portal-axle comprises two shoulders equipped with spindles for mounting wheels and with a central portion for structurally connecting the shoulders. Unlike conventional solutions, the central portion is not made by casting or forging, but advantageously is simply defined by at least two bars coupled thereto during the assembly. The bars are easily available on the market at low cost, have lower weight with respect to a traditional forged/cast component and allow modularity and versatility in dimensioning the portal-axle to be obtained.
US11260689B2 Integrally injection molded wheel with high stability
A stable, low-weight wheel which is particularly suitable for high system-weight bicycles, such as electrically powered bicycles and cargo bikes, includes a hub, at least three solid-body spokes disposed rotationally symmetrical to the wheel axis, and a rim. The body of the hub, spokes and rim is made in one piece by injection molding of a glass-fiber reinforced thermoplastic. The spokes have an S-shaped cross-section with an opening angle which increases in the direction of the rim, taper from the rim towards the hub in a central cross-section of the wheel, and taper from the hub towards the rim in a wheel cross-section running through the center of least one spoke. A method for producing the wheel is also provided.
US11260688B2 Fabric print medium
A fabric printable medium comprising a fabric base substrate, with an image-side and a back-side, having a water proofing treatment including a water-repellant agent applied thereto; an adhesion promoting layer, applied to the image-side of the fabric base substrate, comprising a polymeric compound and a physical networking component; an ink-receiving coating layer over the adhesion promoting layer, comprising a first and a second crosslinked polymeric network; and a barrier layer applied to the back-side of the fabric base substrate, comprising polymeric binders and filler particles with flame retardancy properties. Also disclosed are the method for making such fabric print medium and the method for producing printed images using said material.
US11260680B2 Integrated printing and packaging solution
A printing system for printing images onto a medium supplied as feed-stock, said system comprising a printer, a control computer and data inputting means, a printer head, a cutter, at least one rewinder and a taper; the print head for printing individual work-pieces onto the medium; the cutter for cutting the medium into individual work-pieces, and the at least one rewinder for rewinding the work-pieces into coreless-rolls, and the taper comprising a tape dispenser and printer for printing identifying data onto a piece of tape applied to fasten each coreless roll closed wherein the cutter and the printing of the tape is controlled by the control computer, wherein the cutter is configured to section the work-piece from the feedstock after it has started to be fed into the rewinder.
US11260674B2 Image forming apparatus
An image forming apparatus includes a sheet conveyance portion, a recording portion, a sheet detection portion, and a control portion. In a duplex printing including a first and a second process of printing on a first surface and a second surface of the sheet, in the first process, the control portion calculates a center position of the sheet based on an edge position of the sheet on one side in the width direction and size information of the sheet, prints a first image on the first surface such that the first image is centered on the center position calculated, and prints a reference marker on the first surface. In the second process, the control portion calculates a correction magnification ratio based on a difference between a reading position and the printing position of the reference marker, and corrects a size and a printing position of a second image.
US11260671B2 Printer, computer-readable medium, and method for suppressing reduction in printing speed and deterioration of image quality
A printer includes a print engine and a controller configured to, when a particular condition is satisfied, control the print engine to perform first partial printing to form first dots corresponding to a first portion of a target image without forming second dots corresponding to a second portion of the target image, perform sub scanning over a first distance after the first partial printing and before second partial printing, and perform the second partial printing to form the second dots without forming the first dots, and when the particular condition is not satisfied, control the print engine to perform the first partial printing to form at least a part of the first dots, perform the sub scanning over a second distance different from the first distance after the first partial printing and before second partial printing, and perform the second partial printing to form the second dots.
US11260668B2 Fluid ejection device including recirculation system
A fluid ejection device may include a first channel having a first end and a second end, a first drop ejector along the first channel, a second channel having a first end and a second end, a second drop ejector along the second channel, a third channel extending between and connecting the first end of the first channel and the first end of the second channel, a fourth channel extending between and connecting the second end of the firs channel and the second end of the second channel and a fifth channel extending between and connecting the third channel and the fourth channel.
US11260666B2 Liquid ejection head and liquid ejection apparatus
A liquid ejection head comprises a plurality of ejection orifices for ejecting liquid, a liquid supply flow path for supplying liquid to the plurality of ejection orifices and a plurality of branch flow paths branched from the liquid supply flow path each being held in communication with corresponding one of the plurality of ejection orifices. The plurality of ejection orifices form a first row and a second row each extending in parallel with each other. The first and second rows of ejection orifices are partially overlapping with each other as viewed in the direction orthogonal relative to the extending direction. The flow rate in the branch flow paths held in communication with the ejection orifices located in the overlapping part is made greater than the flow rate in the branch flow paths held in communication with the ejection orifices located in the non-overlapping part.
US11260660B2 Liquid discharge head
A liquid discharge head includes: a first substrate including a pressure chamber; and a second substrate. The first substrate has a first surface in which a nozzle communicating with the pressure chamber is opened and a second surface positioned at an opposite side of the first surface and in which a communication hole communicating with the pressure chamber is opened. The second substrate is joined to the second surface of the first substrate and has a channel communicating with the pressure chamber via the communication hole. The pressure chamber has a first end in a first direction and a center portion in the first direction. The communication hole communicates with the first end of the pressure chamber, and the first end of the pressure chamber is greater than the center portion of the pressure chamber in length in a second direction which intersects with the first direction.
US11260652B2 Print head nozzle spitting
A method is disclosed. The method may involve obtaining information indicative of a number of printing passes of a print head to print a swath on a printable medium. The method may comprise determining that the print head is to perform a particular printing pass which is one of: a printing pass during which an amount of print agent to be deposited from nozzles of the print head differs, by an amount that exceeds a defined threshold, from an amount of print agent to be deposited from the nozzles during a printing pass immediately preceding said particular printing pass; and a printing pass to print a swath which is the first of a plurality of adjacent swaths in which each swath has an area coverage exceeding a defined threshold. The method may comprise preparing, based on said obtained information, a schedule for a nozzle spitting procedure to commence before the print head performs the particular printing pass.
US11260651B2 Dust removal device and printer
A dust removal device for continuous paper improves operability and usability for a user. The continuous paper is continuously supplied in a rightward direction, then through guide rollers, the direction of the continuous paper is reversed leftward. A downward front surface of the continuous paper is cleaned with a first dust removal device. Further, a direction of the continuous paper is reversed with a guide roller rightward. A downward back surface of the continuous paper is cleaned with a second dust removal device, and is guided to the downstream side. The two dust removal devices are provided in a vertical positional relationship in space. Dust removed with a dust removing member falls to a dust receiving member and is stored in the dust receiving member. It is possible to easily dispose the dust by pulling out the dust removal device from a cleaning position to an outside detachment position.
US11260647B2 Apparatus and method for decoupling an element that is bonded to a surface by adhesive
Apparatuses and methods for decoupling an element that is bonded to a surface by an adhesive are provided. In one example, the apparatus includes a body, a first spool that is rotationally coupled to the body, and a cable having a first cable end portion that is coupled to the first spool, a second cable end portion that is coupled to the body, and a cable intermediate portion that is disposed between the first cable end portion and the second cable end portion. The apparatus is configured to be positioned adjacent to at least one of the element and the surface with the cable intermediate portion disposed adjacent to the adhesive such that when the first spool is rotated, the cable wraps about the first spool, thereby pulling the cable intermediate portion through the adhesive.
US11260645B2 Method for manufacturing packaging sheet
A method of manufacturing a packaging sheet, the method being capable of not only greatly improving a heat insulation property of the packaging sheet, but also minimizing the volume of cells of the packaging sheet without opening the cells by cutting or needle-punching the cells, thereby facilitating storage and transportation of the packaging sheets while significantly reducing logistics costs.
US11260642B2 Methods for fast and reversible dry adhesion tuning between composite structures and substrates using dynamically tunable stiffness
Disclosed herein are embodiments of methods that utilize dry adhesion tuning of a composite structure to adhere substrates. In some embodiments, the disclosed methods utilize dry adhesion between a composite structure and a substrate and further dynamically control the resulting dry adhesion strength through a heating step, which facilitates rigidity tuning of a core component of the composite structure and/or facilitates thermal control of the interface between the substrate and the composite structure. Also disclosed herein are array devices and other products comprising the disclosed composite structures.
US11260640B2 Tape lamination machine scrap collection assembly
A scrap collection assembly for a tape lamination head that applies a plurality of composite tape segments includes a crack-off assembly with a scrap crack-off redirect roller configured to engage one or more composite tape segments and one or more scrap portions; a secondary crack-off roller configured to engage one or more composite tape segments and one or more scrap portions; a pivot that connects the crack-off assembly to the tape lamination head, wherein the secondary crack-off roller selectively moves about the pivot to change a direction of composite tape movement; and a conveyor that receives the scrap portion(s) from the secondary crack-off roller.
US11260635B2 Resin composition, method for producing cured article, cured article, flexible substrate, and flexible display
A resin composition resulting in a cured article which is excellent in balance among mechanical strength, surface smoothness, and light transmittance, a method for producing a cured article, a cured article, and a flexible substrate or flexible display including the cured article. The resin composition includes a polyamic acid having a structural unit represented by the following formula (1), a cellulose compound having a weight average molecular weight of 60,000 or less, and an organic solvent. In the formula (1), A is a tetravalent organic group and B is a divalent organic group.
US11260634B2 Laminate and packaging bag comprising same
The objective of the present invention is to provide a packaging bag which is produced from a laminate, which is excellent in straight cut property and which hardly cause a parting, even if the laminate contains a biaxially stretched PBT film having a large distortedness of a molecular orientation axis. The laminate has a biaxially stretched film substrate consisting of a polyester resin composition and a sealant film consisting of a polyolefin resin composition, and has a straight cut property in a longitudinal direction of 5 mm or less. The polyester resin composition contains 60 wt % or more of a polybutylene telephthalate resin, and the polyolefin resin composition contains 40 wt % to 97 wt % of a propylene-ethylene block copolymer, 3 wt % to 10 wt % of an ethylene-propylene copolymer elastomer, and 0 wt % to 50 wt % of an ethylene-αolefin random copolymer.
US11260632B2 Lactic acid polymer films
A multilayer film comprises (a) two or more non-plasticized layers comprising lactic acid polymer and (b) one or more plasticized layers comprising lactic acid polymer and plasticizer sandwiched between the two or more lactic acid polymer layers; wherein the thickness of the one or more plasticized layers comprises from about 60% to about 70% of the total thickness of the multilayer film.
US11260631B2 Multilayer polyurethane protective films
The present invention relates to multilayer films used to protect a surface, in particular, to such films used to protect surfaces of articles e.g., mobile electronics display protections, smartphones, tablets), industrial touch screens (e.g. machine interfaces), UV stable surfaces and glass protections for machine housings and cockpits (e.g. caterpillars, dumpers), etc.), and, more particularly, to such a multilayer protective film backed by a silicone-based pressure sensitive adhesive (PSA) and having either an aliphatic polyurethane layer or an aliphatic thermoplastic polyurethane layer on top of an aliphatic thermoplastic polyurethane layer, where the two aliphatic polyurethane layers have different physical and/or chemical properties. The present invention also relates to an article that is protected by the multilayer film as well as a method for making the multilayer protective film.
US11260628B2 Fabrication process for laminated glass comprising a functional film
Laminated glass contains two glass sheets interlayered with at least one polymer film C which is provided with a coating A comprising a polyvinyl acetal PA and optionally at least one plasticiser WA, and at least one film B containing a polyvinyl acetal PB and at least one plasticiser WB wherein coating A comprises less than 16% by weight of plasticiser, film B comprises at least 16% by weight of plasticiser, and film C comprises polyamide, polyethylene terephthalate, polybutylene terephthalate, polyvinyl alcohol, polylactic acid, polyethylen furanoate cellulose acetate, polymethyl methacrylates, polyethylene naphthalate, ionomers, or combinations thereof, wherein film C is located between coating A and film B.
US11260625B2 Biodegradable and compostable multilayer film
The present disclosure provides a biodegradable and compostable multilayer film. The biodegradable and compostable multilayer film comprises a sealant product side layer comprising at least one slip additive and having a pre-determined co-efficient of friction, an outer surface layer, and at least one intermediate layer disposed between the sealant product 5 side layer and the outer surface layer. The biodegradable and compostable multilayer film of the present disclosure has good mechanical properties and is non-reactive with tobacco based products, medicines, and food products to be packaged.
US11260623B2 Panel suitable for forming a floor covering, process for producing a panel, use of an adhesive precursor
A panel suitable for forming a floor covering by assembling a plurality of said panels adjacent to each other,which is of a substantially planar design, having a planar top side and a planar bottom side, said panel being composed from a layered structure that comprises: a waterproof core layer; a top layer adhered on the top side of said core layer, wherein the top layer comprises at least one ply of cured resin impregnated paper; an adhesive layer between the core layer and the top layer; characterized in that the adhesive layer is a cured mixture which comprises a polymeric adhesive compound, and an additional constituent which is either at least one resin component which is also present in the cured resin impregnated paper, and which is not included in the polymeric adhesive compound, or an epoxy resin.
US11260621B2 Low weight modular carpet components and methods of making the same
A low-weight carpet tile and process for making the same, wherein the carpet tile comprises a facecloth having a plurality of face yarns tufted through a primary backing, an extruded polymer secondary backing layer, and a reinforcing scrim layer partially embedded within the extruded polymer secondary backing layer. The top surface and bottom surface of the carpet tile are defined by the facecloth and the reinforcing scrim layer, respectively. A polymer-based resin is extruded onto the facecloth to form an at least substantially uniform secondary backing layer, and the reinforcing scrim layer is laid onto the extruded polymer secondary backing layer while the extruded polymer secondary backing layer remains above a softening temperature for the resin. The entire multi-layer web is then passed through a nip to embed the reinforcing scrim layer into the extruded polymer secondary layer, and the entire web is chilled.
US11260619B2 Composite panel systems and methods
A composite panel assembly and method of forming the same includes a core, an inner skin coupled to a first side of the core, and an outer skin coupled to a second side of the core. A peripheral edge including portions of the core, the inner skin, and the outer skin, is compressed to close a path into the core.
US11260616B2 Method for producing corrugated board
An apparatus is provided for producing longitudinally corrugated product. The apparatus includes a guide roll for guiding a web of medium material, wherein at least a portion of the guide roll is adapted to be arranged at an angle relative to another portion of the guide roll. The apparatus further includes a plurality of flute forming bars oriented generally along a longitudinal axis of the web to define a first corrugating labyrinth effective to longitudinally corrugate the web to an intermediate geometry. The apparatus further includes a pair of corrugating rollers that cooperate to define, at a nip therebetween, a second corrugating labyrinth effective to longitudinally corrugate the web to a substantially final geometry. The apparatus further includes a web travel pathway for the web that follows a path around a portion of the guide roll, through the first corrugating labyrinth, and through the second corrugating labyrinth.
US11260613B2 Tire vulcanizing mold
A tire vulcanizing mold comprises a sidewall ring for molding a sidewall portion of a tire. The sidewall ring is composed of a main body provided with a circumferentially extending groove, and mold pieces mounted in the groove so as to be adjacent to each other in the circumferential direction. Between the mold pieces and/or between the main body and the mold pieces, there are formed micro-gaps for discharging gas existing in the tire vulcanizing mold so as to communicate with exhaust flow paths extending from the groove toward the outside of the mold.
US11260612B2 Methods and compositions for pigmented hydrogels and contact lenses
In general, the disclosure relates to methods and compositions for preparing colorants useful for preparing pigmented hydrogels. The disclosure further relates to pigmented hydrogels comprising the disclosed colorants. In some instances, the colorant is an alcohol extract of an agro-material, such as turmeric, paprika, spinach, and/or woad or the colorants comprise one or more of: a carotenoid, chlorophyll-a, chlorophyll-b, a curcumoid, or indigorubin. Alternatively, the colorant can be carbon black. The disclosure further relates to contact lenses comprising the disclosed pigmented hydrogels.
US11260611B2 Identifiable composite rework system and method
Aspects of the present disclosure are directed to a doped composite rework material including a fiber-containing material, a resin-containing material, and a dopant, with the dopant configured to impart an identifying characteristic to the doped composite rework material; and methods for precluding rework of a previously reworked composite material.
US11260604B2 Method and system for dispensing molten wax into molds by means of a desktop apparatus
Method and system for dispensing molten wax into molds by means of a desktop apparatus is disclosed. The invention being comprised of a heating chamber, temperature controller, metering dispenser, adjustable base, lighting strip and protective viewing cabinet. Said invention allowing wax to be melted and maintained at a temperature below the melting point of mold materials such as; but not limited to, filaments commonly used in 3D printing and the like. An object of the invention is to allow users to quickly position and fill custom molds for fabrication processes such as candle and jewelry making.
US11260601B2 System for printing binding agents
A system for fabricating a three-dimensional article includes a fluid supply with binding agent, a printhead, a powder dispenser, and a controller. The fluid supply is for containing a binding agent. The controller is configured to (a) operate the fluid supply and/or the printhead to elevate a temperature of the binding agent to above 25 degrees Celsius, (b) operate the dispenser to dispose a layer of the powder at a build plane, (c) scan and operate the printhead to selectively jet the binding agent onto the layer of powder to bind a layer of the three-dimensional article, and (d) repeat operating the dispenser and scanning and operating the printhead to complete fabrication of the article. Jetting or not jetting the binding agent includes individually operating drop ejectors of the printhead using a voltage waveform. The waveform can include one or more of a non-ejecting pulse and an ejecting pulse.
US11260600B2 Method for calibrating an irradiation device for an apparatus for additively manufacturing three-dimensional objects
Methods for calibrating an irradiation device for an apparatus for additively manufacturing three-dimensional objects include generating at least two first and two second calibration patterns, in at least two different first positions and at least two different second positions; determining position information relating to the positions of the calibration patterns; generating a calibration quality value relating to a calibration status of the irradiation device; simulating at least two first calibration patterns and at least two second calibration patterns based on at least one changed irradiation parameter; determining a calibration quality value for the simulated calibration patterns; and repeating the simulation and determination of the calibration quality value until a maximum or minimum calibration quality value is reached.
US11260599B2 Modulating a three-dimensional printer system based on a selected mode
A control system for a three-dimensional printer includes an energy component interface, an agent depositing component interface, and control logic. The control logic controls the operation of an energy component through the energy component interface and an agent depositing component through the agent depositing component, in forming an output object that is specified in a print job. Additionally, in some examples, the control logic can implement a plurality of modes. Each mode, when selected modulate one or more operational parameters of a least one of the energy component or agent depositing component.
US11260597B2 Systems and methods for characterizing a foot of an individual
A method for generating an orthotic device is disclosed. The method includes receiving data from a client device of a patient, the data comprising patient information and image data representative of a body part of the patient. The method further includes generating, based on the image data, three-dimensional model data representative of the body part, and generating parametric CAD model data of the orthotic device based on the three-dimensional model data and the patient information. The parametric CAD model data is transmitted to a three-dimensional printer, wherein the three-dimensional printer is to generate the orthotic device based on the parametric CAD model data.
US11260591B2 Supplying build material
According to one example there is provided a method of delivering build material from a build material store to a supply module. The method comprises moving, using a rotatable vane, a portion of build material from the supply module to the top of the supply module, and spreading the moved portion of build material across the support platform.
US11260587B2 3D printhead comprising additional temperature control means
Printhead (10) for a 3D printer, comprising an operational volume (17) for holding feedstock (20), the viscosity of which can change, the operational volume (17) being variable by moving a plunger (31, 31a, 31b) and being provided with an outlet (16) through which the feedstock (20) can be extruded by moving the plunger (31, 31a, 31b), the plunger (31, 31a, 31b) being equipped with temperature control means (36).
US11260584B2 Method and device for producing a three-dimensional workpiece
The invention relates to a method for producing a three-dimensional workpiece. The method comprises irradiating a raw material layer with a laser beam, wherein a melt bath is produced at a point at which the laser beam impinges on the raw material layer, changing a position of the laser beam on the raw material layer with the aid of a first diverting unit and changing the position of the laser beam on the raw material layer with the aid of a second diverting unit. The second diverting unit is designed to divert the position of the laser beam with a greater acceleration than a maximum possible acceleration of a diversion by the first diverting unit. The invention also relates to a device for producing a three-dimensional workpiece.
US11260582B2 Methods and apparatus for manufacturing optimized panels and other composite structures
The disclosure relates to additively manufactured (AM) composite structures such as panels for use in transport structures or other mechanized assemblies. An AM core may be optimized for an intended application of a panel. In various embodiments, one or more values such as strength, stiffness, density, energy absorption, ductility, etc. may be optimized in a single AM core to vary across the AM core in one or more directions for supporting expected load conditions. In an embodiment, the expected load conditions may include forces applied to the AM core or corresponding panel from different directions in up to three dimensions. Where the structure is a panel, face sheets may be affixed to respective sides of the core. The AM core may be a custom honeycomb structure. In other embodiments, the face sheets may have custom 3-D profiles formed traditionally or through additive manufacturing to enable structural panels with complex profiles. The AM core may include a protrusion to provide fixturing features to enable external connections. In other embodiments, inserts, fasteners, or internal channels may be co-printed with the core. In still other embodiments, the AM core may be used in a composite structure such as, for example a rotor blade or a vehicle component.
US11260581B2 Jetted material printer with pressure-assisted fluid extraction
A three-dimensional (3D) inkjet printer is configured to build up an object by printing a series of layers and stacking them to form the object. In order to speed printing, drying of each layer is accelerated by using a pressure differential to extract liquid vehicle from the ink, and by moving the printed layer away from the inkjet print heads before drying so that the inkjet print heads may print the next layer. The dried printed layer may also be conditioned and/or cured. Dried printed layers are stacked at a build station to assemble the finished object.
US11260580B2 Closed loop print process adjustment based on real time feedback
In some embodiments, a photoreactive 3D printing system and methods comprise providing a system with a resin tub comprising a membrane, wherein the membrane rests on a physical tension element such that increasing downward force on the resin tub induces increasing tension on the membrane. The system also comprises a plurality of sensors comprising a resin bulk temperature sensor, and a print recipe comprising information for each layer in a 3D printed part to be built on the print platform. In some embodiments, a resin bulk temperature is measured, and the information in the print recipe, including information related to the downward force on the resin tub, is updated during a printing run based on the resin bulk temperature measurement. In some embodiments, the print recipe can be updated during a printing run based on input from at least two sensors of the plurality of sensors.
US11260575B2 Method for producing resin vessel made of resin, mould unit and moulding apparatus
Provided is a method for manufacturing a container 10 made of resin, the method including an injection molding step S1, a temperature adjustment step S2, and a blow molding step S3. In the temperature adjustment step S2, a preform 11 is accommodated in a cavity mold 31, an air introduction member 32 is brought into airtight contact with the preform 11, the air is supplied from a blowing port of the air introduction member 32 into the preform 11, and the air is discharged from a discharge port of the air introduction member 32 to an outside of the preform 11, so that the preform 11 is in close contact with an inner wall of the cavity mold 31 and is cooled.
US11260564B2 Method for manufacturing foam molded body and foam molded body
A method for producing a foam-molded product by using a plasticizing cylinder, includes: plasticizing and melting the thermoplastic resin to provide the molten resin in a plasticization zone of the plasticizing cylinder; introducing a pressurized fluid containing the physical foaming agent at a fixed pressure into a starvation zone of the plasticizing cylinder to retain the starvation zone at the fixed pressure; allowing the molten resin to be in the starved state in the starvation zone; bringing the molten resin in contact with the pressurized fluid containing the physical foaming agent at the fixed pressure, in the starvation zone in a state in which the starvation zone is retained at the fixed pressure; and molding the molten resin having been brought in contact with the pressurized fluid containing the physical foaming agent into the foam-molded product.
US11260560B2 Cement supply control systems and methods
A system comprises a cement mixer, a supply tank to supply dry cement to the cement mixer, and a dry cement height sensor to measure the height of the dry cement in the cement supply tank. A valve controls the flow of dry cement to the cement supply tank based on the signals from the dry cement height sensor. Additional apparatus, methods, and systems are disclosed.
US11260559B2 Automatic washout system for a mixer vehicle
A washout system for a concrete mixer vehicle includes a plurality of valves, a plurality of nozzles, and a controller. The plurality of valves are configured to (i) be fluidly coupled to a pump and a fluid tank and (ii) receive a fluid from the pump. One or more of the plurality of nozzles are fluidly coupled to a respective one of the plurality of valves. Each of the plurality of nozzles are configured to provide the fluid to a respective target when the respective one of the plurality of valves is selectively activated to an open position. The controller is configured to monitor a plurality of washout parameters during operation of the concrete mixer vehicle and initiate one of a plurality of washout modes in response to a subset of the plurality of washout parameters being satisfied for the one of the plurality of washout modes.
US11260551B2 Ultrasonic cutter
An ultrasonic cutter cuts edge chamfers of plate-shaped workpieces using a cutter head which forms an axis of rotation and a blade which extends from the cutter head and forms a cutting wedge, terminating in a straight cutting edge, between flank and contact faces determined by the wedge angle. In order to create advantageous structural conditions, the axis of rotation extending on the blade side of the flank face is at a distance from the flank face which is equal to or greater than the distance of the center of mass of the blade from the flank face and the cutting edge, extending in the direction of the axis of rotation, extends at a distance from the axis of rotation which corresponds at most to the blade thickness.
US11260548B2 Hair cutting device
A hair cutting device includes a grip, a head disposed external to one end of the grip, the head including a cutting unit that works on hair, and a joint connecting the grip and the head. The joint includes a base connected to one of the grip and the head, and a slide portion connected to the other of the grip and head and held to be slidable within a predetermined area on a slide plane that is a plane intersecting an alignment of the grip and the head. Accordingly, the hair cutting device including the head that has an excellent ability to lessen impact which is made when the head hits the skin and to follow the skin surface is provided.
US11260547B1 Electric utility knife
An electric utility knife having a blade which can facilitate manual precision cutting, at a singular consistent speed or varying speeds, without requiring the user to exert extreme or substantial manual pressure to cut through a material. The blade can be configured as a vibrating/oscillating/rotating blade to perform a majority of the cutting tasks. The user may simply guide the blade and exert minimal manual pressure on the knife. This can reduce the potential for injury and other repetitive motion stress injuries to a user. This can also facilitate greater cutting precision and can reduce cutting time.
US11260546B2 Robot
A robot having joint shaft that includes: a first-link member and a second-link that are coupled about a rotation axis; a reducer that has an input-shaft fixed to the first-link and an output-shaft fixed to the second-link; a motor that generates a driving force to be input to the reducer; and an input-side encoder and an output-side encoder. The motor is away from the rotation axis, and a power transmission mechanism is provided between the motor and the reducer. The reducer includes a hollow-part and a tubular-member. The tubular-member passes through the hollow-part, one end of which is fixed to the input-shaft or the output-shaft, and the other end of which protrudes from the input-shaft or the output-shaft. The output-side encoder includes a scale and a sensor. The scale is fixed to the tubular-member; and the sensor is fixed to the input-shaft or the output-shaft.
US11260539B2 Gripper apparatus for multi object grasping and stacking
Object manipulation space optimization is a challenging task and used in applications such as heat treatment operation and transport packaging. Traditionally manual intervention is involved to grasp and place the objects for ensuring multi object stacking with zero gap between adjacent objects. This leads to higher cost infrastructure and low productivity. Further, conventional gripper devices fail to optimize object manipulation space and are unable to handle objects of different cross sections with larger lengths. The present disclosure provides a gripper apparatus addressing a single gripper design comprising an adaptor holding unit with a provision for different modular object holding units which are varied in accordance with size, shape and length of the object to be grasped and placed by the gripper apparatus. The modular object holding unit comprises a plurality of fingers which are actuated for grasping and stacking one or more objects such that object manipulation space is optimized.
US11260538B2 Robot training system including a motion bar
A teaching system for a robot is provided, including a motion bar for controlling the robot and a robot system utilizing the teaching system. In one embodiment, the teaching system is provided including a first controller configured to provide motion-related control functions for controlling motion of the robot. The teaching system may also include a second controller configured to provide control functions other than the motion-related control functions for programming one or more actions of the robot.
US11260537B2 Machine tool for robot-assisted surface finishing
The invention relates to a machine tool for robot-assisted surface finishing. According to one embodiment, the machine tool comprises a first support plate and a second support plate. The first support plate is designed for mounting on a manipulator. An output shaft for receiving a rotatable tool is mounted on the second support plate. The machine tool additionally comprises a linear actuator that acts between the first support plate and the second support plate, as well as a motor which is mounted on the first support plate. The machine tool additionally comprises a telescopic shaft with a first shaft portion and a second shaft portion that can be displaced relative to said first shaft portion. The first shaft portion is coupled to a motor shaft of the motor, and the second shaft portion as mounted on the second support plate. The telescopic shaft is coupled to the output shaft by means of a gear mechanism.
US11260536B1 Simulation of emotional state of an interactive device
A simulated emotional state of a device is generated and maintained based on previous emotional state and contextual information. A trigger is associated with an effect value. For example, successful completion of a task may have an effect value of +5 while task failure may have an effect value of −6. Upon occurrence of a trigger, an associated effect value of the trigger may be combined with a previously determined effect value to determine a function input value (FIV). The FIV is used as input to a function that provides an emotion value as output. The emotion value may then be used as input to determine a particular action. For example, if the emotion value corresponds to “happy”, the resulting action may be presenting an animation of a smile on a display device. As triggers occur, the function input value is updated, resulting in updates to the emotion value.
US11260530B2 Upper limb motion support apparatus and upper limb motion support system
An upper limb motion support apparatus and an upper limb motion support system which are capable of significantly improving the enhancement of an operator's work efficiency and the reduction of their workload are proposed. A controller which causes an articulated arm and an end effector to perform three-dimensional motion according to the operator's intention based on a biological signal acquired by a biological signal detection unit causes the articulated arm and the end effector to perform cooperative motion in conjunction with the operator's upper limb motion by referring to content recognized by an upper limb motion recognition unit.
US11260525B2 Master robot for controlling slave robot and driving method thereof
Disclosed is a master robot for controlling at least one slave robot. The master robot includes a communicator that communicates with the slave robot or a mobile terminal, at least one sensor, an inputter that inputs an image signal or an audio signal, and a controller that creates a space map corresponding to a predetermined space in which the master robot and the slave robot are located on the basis of information sensed by the sensor or information inputted through the inputter. Accordingly, a master robot equipped with artificial intelligence and a 5G communication module can be provided.
US11260524B2 Direct access dispensing system
An access and storage system including a storage component configured to store items therein or thereon in an associated storage position, wherein the storage component is configured to provide a user direct manual access to the items in the storage positions. The system further includes a sensor system configured to track at least one of the user's removal of an item from the associated storage position or replacement of an item to the associated storage position and an identification system for identifying the user. The system also has an authorization database operatively coupled to the identification system for tracking which of the items a particular identified user is authorized to access.
US11260521B2 Hand grip element with a hand grip body for activating an upright posture of the human body
A grip element having an elongate grip body with a first end region and a second end region. The grip body has a first surface near the second end region, with a curved subregion for supporting a subregion of the ball of the human hand, and an outwardly curved second surface supporting a subregion of the palm, and an inwardly curved third surface adjacent to the first surface and supporting the extended thumb, and an outwardly curved fourth surface lying substantially opposite the third surface and supporting the middle finger, adjacent to which fourth surface an outwardly curved fifth surface is provided for supporting the ring finger. The grip body has a sixth surface to support the index finger. The sixth surface, starting from a subregion of the second surface spaced apart from the second end region of the grip body, extends in the direction to the first end region and runs longitudinally along the grip body.
US11260518B2 Ergonomic handle for power tool
An ergonomic handle is disclosed for use with a power tool, the power tool having a power source, a housing containing a source of motion, and a tool holder coupled the housing and defining a tool holder axis and a forward direction toward a working end of the tool and rearward direction away from the working end of the tool. The handle includes a handle portion having a proximal end coupled to the housing and a distal end coupleable to the power source, and defining, from the proximal end to the distal end, a first region, a second region, a third region, and a fourth region, and defining a handle axis that is generally transverse to the tool holder axis. The first region includes a switch for actuating the source of motion and adapted to receive a user's thumb and forefinger when the forefinger is actuating the switch. The second region is adapted to receive the user's middle finger, the third region is adapted to receive the user's ring finger; and the fourth region adapted to receive the user's pinky finger. Each of the second region, the third region, and the fourth region includes a generally oval cross section having a major axis and a minor axis. The cross section having the longest major axis is positioned in the third region, the cross section having the shortest major axis is positioned in the fourth region, the cross section having the shortest minor axis is positioned in the second region, and the cross section having the longest minor axis is positioned in the fourth region.
US11260513B2 Powered fastening device with depth shutoff
A powered fastening device is provided and is capable of applying multiple strikes to a fastener to drive the fastener to a preselected depth in a work piece and then automatically stopping the strikes when the preselected depth has been achieved.
US11260510B2 Tool with label structure
A tool of the present invention includes a tool main body and a matte silver polyester label. The outer surface of the tool main body has a label region. The matte silver polyester label has an indicate surface and a glue surface opposite to the indicate surface. The indicate surface has one or more identification marks represented by words, colors, numbers, patterns or figures. The glue surface is stuck in the label region of the tool main body. As a result, the tool of the present invention provides great identification effect.
US11260505B2 Ratcheting driver
A ratcheting driver comprises a driving mechanism combined between a handle and a working end for translating rotary motion from the handle to the working end. A switch engages the driving mechanism to switch the rotational direction of the working end between clockwise rotation and counter-clockwise rotation with an optional locked position that locks the working end. Two pairs of cooperating pawls are provided that are selectively engaged by the switch with one pawl in each of the two pairs of cooperating pawls selectively engaging one of a first ratchet gear and a second ratchet gear. Each pawl in the pair of cooperating pawls are positioned axially apart from each other in alignment with one of the first ratchet gear and the second ratchet gear.
US11260501B2 Method and grinding machine for measuring and producing a target outer contour of a workpiece by means of grinding
A grinding machine and a method for measuring and producing a target outer contour is disclosed, particularly for a pin-bearing journal of a crankshaft. First, a measurement device acquires measurement values for the dimensions and shape of a workpiece in at least two measurement planes that are spaced apart and extend transversely to a longitudinal extension of a workpiece region. The measurement planes are produced by a relative movement of the workpiece region and the measurement device in a Z axis direction, relative to the movement of a grinding disc in the direction of the Z-axis thereof. These measurement values are transmitted to a CNC system for advancing a grinding disc, such that any deviations from the target contour that may be present are corrected, and the target contour of the workpiece region in question is ground adaptively on the basis of the measurement values.
US11260496B2 Polishing method and polishing apparatus
A polishing method which can acquire an actual position of a film-thickness measurement point, and can therefore apply an optimum polishing pressure to a substrate such as a wafer is disclosed. The method includes: causing a substrate detection sensor to generate substrate detection signals in a preset cycle and causing a film-thickness sensor to generate a film-thickness signal at a predetermined measurement point during polishing of the substrate while the substrate detection sensor and the film-thickness sensor are moving across the surface of the substrate; calculating an angle of eccentricity of a center of the substrate relative to a center of the polishing head from the number of substrate detection signals; correcting a position of the predetermined measurement point based on the angle of eccentricity; and controlling polishing pressure at which the polishing head presses the substrate based on the film-thickness signal and the corrected position of the predetermined measurement point.
US11260493B2 Substrate processing apparatus and control method
A substrate processing apparatus which causes a processing tape to abut against a processing object, including: a tape supply reel configured to supply the processing tape; a tape recovery reel configured to recover the processing tape; a recovery motor configured to apply a torque to the tape recovery reel; a tape feed motor configured to feed the processing tape between the tape supply reel and the tape recovery reel; and a control unit configured to control the tape feed motor, wherein the control unit controls the torque of the recovery motor depending on a change in an outer diameter of a roll of the processing tape wound by the tape recovery reel such that tension applied to the processing tape is constant, using a feed length of the tape fed by the tape feed motor and a thickness of the processing tape.
US11260491B2 Method for grinding tip of rotor blade, and jig for grinding up of blisk
When a tip of a blade cascade is ground with a grindstone, a jig is inserted between blade cascades of a blisk and a jig is inserted between blade cascades. A blade locking section of the jig locks with a side section in the width direction of a corresponding rotor blade via a damping member made from rubber or the like. A disk locking section of the jig locks with a disk of the blade cascade which the blade locking section locks with.
US11260487B2 Machine-tool seal member
A sealing member for machine tools is capable of keeping sealing performance. The sealing member includes a support member and an elastic member formed in a flat plate shape. The elastic member includes an edge portion to slide on a sliding surface of a machine tool. The support member has a support surface facing a part of a front surface of the elastic member. The sealing member is mounted to the machine tool such that the elastic member is sandwiched between a mount portion of the machine tool and the support surface of the support member. The elastic member has a fixed portion sandwiched between the mount portion and the support member. A lip portion not sandwiched between the mount portion and the support member when the sealing member is mounted to the machine tool, the lip portion including the edge portion and configured to be curved.
US11260486B2 Clamping fixture, in particular a vice
In a clamping fixture 1, in particular a vice, with a housing (2) in which a guide track (10) is provided and with at least one base jaw (3, 4) to each of which a clamping jaw (6, 7) can be attached, the cavities or air gaps (21) between the inner wall of the guide grooves (10) and the base jaws (3, 4) should be completely covered.This is achieved in that a seal (11) is inserted into each of the air gaps (21) existing in the housing 2 between the base jaw (3, 4) and the inner wall of the guide track (10) as well as in the parting plane between the base jaws (6, 4) and at the face ends (16) in the area of the guide track (10) running there, and that the particular seal (11) is held in a specified position by means of a support strip (12).
US11260481B2 Screw guide device and screw-fastening robot system
A screw fastening process can be performed by reliably positioning a screw in a screw hole while suppressing a decrease in the degree of freedom of movement of a screw fastening device. Provided is a screw guide device that guides a screw to a screw hole. The screw is fastened by a screw fastening device to the screw hole formed in a workpiece to be fastened to be fastened. The screw guide device includes a guide device body provided at a support that supports the workpiece to be fastened, and also includes a guide member that is provided in the guide device body and that is openable and closable in a radial direction orthogonal to a central axis of a shaft section of the screw. The guide member forms a screw insert through which the shaft section is inserted when the guide member is in a closed state.
US11260479B2 Station and method for inserting a component in an assembly to be assembled
An insertion station of a component (2), for example a clevis, in a component seat (12) formed in an assembly (3) to be assembled, for example a hinge assembly for doors, includes a component ordering device (14) to order the loose components coming from a component feed hopper. A component support seat (16) receives the component and is configured in such a way as to guide the component in the horizontal insertion direction. A manipulator (20) picks a component (2) from the component ordering device (14) and deposit the component in the component support seat (16). An insertion actuator (30) has a pusher member (32) operable to push the component (2) in the component seat (12), and a positioning unit (40), including an abutment (42) operable to block the assembly (3) in a component insertion position.
US11260475B2 Method and system for powder bed fusion additive manufacturing of crack-free aluminum alloys
A method of forming a crack-free aluminum alloy structure using additive manufacturing is presented. A powder bed of precursor aluminum alloy powder is heated. The crack-free aluminum alloy structure is formed within a laser powder bed fusion system encompassing the powder bed during heating.
US11260474B2 Manufacturing machine
A manufacturing machine is capable of subtractive manufacturing and additive manufacturing for a workpiece. The manufacturing machine includes: a first headstock and a second headstock disposed in a machining area and configured to hold a workpiece; a tool spindle and a lower tool rest disposed in the machining area and configured to hold a tool to be used for subtractive manufacturing for the workpiece; an additive manufacturing head configured to discharge a material during additive manufacturing for the workpiece; a workpiece gripper configured to grip the workpiece during transportation of the workpiece into and out of the machining area; and a robot arm on which the additive manufacturing head and the workpiece gripper are mountable. Accordingly, the manufacturing machine improving the productivity in the simple and easy manner is provided.
US11260472B2 Method and system for extending optics lifetime in laser processing apparatus
Methods and apparatus for extending the lifetime of optical components are disclosed. A beam of laser energy directed along a beam path that intersects a scan lens, through which it can be transmitted. The beam path can be deflected within a scan region of the scan lens to process a workpiece with the laser energy transmitted by the scan lens. The scan region can be shifted to a different location within the scan lens, e.g., to delay or avoid accumulation of laser-induced damage within the scan lens, while processing a workpiece.
US11260471B2 Method and device for monitoring a joining seam during joining by means of a laser beam
A method for monitoring a joining seam, in particular during joining by a laser beam, wherein in the processing direction before a processing point a joining site is measured in order to detect the position and geometry thereof, at least one position of a joining seam is determined from the position of the joining point, and in the processing direction after the processing point the joining seam is measured in order to detect the geometry thereof at the determined position. A device is also provided for carrying out said method and to a laser processing head equipped with such a device.
US11260467B1 Canister and method of production
A method of forming a canister by means of a mechanical bonding of respective layers of a first metal material (tantalum) and a second metal material (niobium) to form a sheet stock, thereby forming the sheet stock into a canister form, wherein the first metal material comprises tantalum and the second metal material comprises at least one of niobium, molybdenum, or steel. The completed canister comprises a first metal material comprising tantalum, and a second metal material mechanically bonded to the first metal material by subjecting the first and second metal materials to at least 1,000,000 psi, to thereby form a canister having an inner diameter of 13-19 millimeters (mm), the second metal material comprising at least one of niobium, molybdenum, or steel.
US11260466B2 Wire shuttle for use in welding applications
Apparatuses, systems, and/or methods for welding systems that provide independent control of a contact tip of a welding torch are disclosed. The welding system can include, for example, a welding torch that includes, for example, a contact tip and a pivot in which the contact tip is coupled to the pivot and is configured to provide wire that is fed through the welding torch during a welding operation. The contact tip and the pivot are configured to independently move the contact tip of the welding torch around the pivot during the welding operation.
US11260465B2 Portable AC-DC multi-process welding and cutting machine
A multi-process welding machine provides an intuitive user interface to enable a user to select among different welding processes, and to select parameters for a given selected welding process. The multi-process welding machine also provides an arrangement by which a switching module, or DC to AC converter, of an AC TIG unit can be controlled to alternatively supply AC or DC welding voltages or current. Further, a configuration of switches can be leveraged to automatically (or manually) control the polarity of welding cables for different processes and to engage or disengage a wire feeder when, e.g., a MIG welding process is selected, or not selected, respectively. Finally, in an embodiment, the ferrite or magnetic materials used for a main output inductor and an high frequency starting inductor of the welding machine can be combined.
US11260460B2 Stop for a drilling, milling or countersinking tool
A stop for a rotating drilling, milling or countersinking tool comprising a stop sleeve coupled to a radial rolling bearing in such a way that it freely rotates about the tool, an outer bearing bush of the radial rolling bearing being attached to the stop sleeve and an inner bearing bush of the radial rolling bearing being attached to a shaft sleeve that can be attached to a tool shaft of the tool. An axial rolling bearing is also provided, a housing washer of the axial rolling bearing being supported on the stop sleeve and a shaft washer of the axial rolling bearing being supported on the shaft sleeve. In a secondary aspect, the invention relates to a drilling, milling or countersinking tool provided with such a stop.
US11260459B2 Tools and methods for forming aligned holes from near full-sized holes
Tools and methods for creating a plurality of aligned holes from a plurality of near full-sized holes. The tool includes a cutting member having a first diameter and a pilot member connected to and coaxial with the cutting member. A first section of the pilot member includes a centering member and is positioned between the cutting member and the second section having a second diameter. The centering member may include a cutting surface. The second diameter corresponds to a positional tolerance of misalignment of a plurality of near full-sized holes of the same diameter and a full-size hole diameter. The centering member may have a third diameter between the first and second diameters. The centering member may be tapered. The pilot member may be inserted into a plurality of near-full sized holes and the cutting member may cut through the holes to form a plurality of aligned full sized holes.
US11260452B2 Method for producing nickel nanopowder
A method for producing nickel nanopowder is introduced. For this, the present invention relates to a method for producing nickel nanopowder, including: (a) a step of preparing nickel oxide configured in the form of an oxide; (b) a nickel oxide nanopowder production step of pulverizing the nickel oxide so as to produce nano-sized nickel oxide nanopowder; (c) a step of drying the nickel oxide nanopowder; (d) a step of heat-treating the nickel oxide nanopowder so as to produce natural metal nickel nanopowder; and (e) a step of crushing the heat-treated nickel oxide nanopowder.
US11260439B2 Aluminum alloy strip with improved surface appearance
The invention relates to an aluminum alloy strip with improved surface optics, which is fabricated via hot and/or cold rolling, and consists of a type AA 3xxx, AA 5xxx, AA 6xxx or AA 8xxx aluminum alloy. The object of proposing an aluminum alloy strip that is suitable for attractive and precious surface optics despite the elevated percentage of alloy constituents is achieved in that, after degreasing, the finish-rolled aluminum alloy strip exhibits an increase in the luminance value L*(ΔL) in relation to the rolled-greasy state of more than 5 while measuring the color of the surface in the CIE L*a*b* color space using a standard illuminant D65 and a normal observation angle of 10°, excluding direct reflection in 45°/0° geometry.
US11260435B2 Method and apparatus for cleaning and removing contaminants from the interior of a lubricant run-down tank
A method and apparatus for cleaning, and removing contaminants from the interior of a lubrication rundown tank of a mechanical system provides a source of pressurized and heated cleaning fluid containing at least one solvent; a first jumper hose communicating between the source of pressurized cleaning fluid and the interior of the lubrication rundown tank; a second jumper hose communicating between the interior of the lubrication rundown tank and a dirty fluid collection body; and an outlet spray nozzle carried by a nozzle extension placed within the interior of the lubrication rundown tank and in fluid communication with the source of pressurized and heated cleaning fluid to receive the pressurized and heated cleaning fluid therefrom.
US11260433B2 Cleaning method of substrate processing apparatus and substrate processing apparatus
There is provided a cleaning method of a substrate processing apparatus comprising cleaning an inside of an exhaust pipe through which a gas of an inside of a processing container is exhausted. The cleaning the inside of the exhaust pipe includes: removing a deposit on a downstream side of an opening/closing valve in the exhaust pipe by supplying a first exhaust pipe cleaning gas containing fluorine to the downstream side of the opening/closing valve in the exhaust pipe in a state in which the opening/closing valve provided in a middle of the exhaust pipe is closed; and removing a deposit on an upstream side of the opening/closing valve in the exhaust pipe by supplying a second exhaust pipe cleaning gas not containing fluorine as a gas constituent element to the inside of the processing container in a state in which the opening/closing valve is opened.
US11260429B2 Substrate treating apparatus and substrate transporting method
A substrate treating apparatus and a substrate transporting method wherein a platform is disposed on a first ID block, and a platform is placed on a second ID block. A currently-used carrier platform is provided only on the first ID block. Accordingly, a substrate is transported in both a forward path and a return path between the first ID block and a second treating block. The substrate is returned not to the first ID block but to the second ID block disposed between the two treating blocks in the return path.
US11260427B2 Vacuum apparatus and recovery support method
A vacuum apparatus equipped with an automatic transport mechanism for transporting a specimen and a sensor for detecting a state of the vacuum apparatus includes: a determining unit which determines whether a recoverable error has occurred based on a signal from the sensor; and a display control unit which causes, when it is determined that a recoverable error has occurred, a display unit to display a procedure of a recovery operation in a wizard format. The display control unit determines whether the recovery operation has been performed according to the procedure displayed on the display unit based on a signal from the sensor, and causes the display unit to display a next procedure of the recovery operation when it is determined that the recovery operation has been performed according to the procedure.
US11260424B2 Contoured electrode for capacitive micromachined ultrasonic transducer
Aspects of this disclosure relate to a capacitive micromachined ultrasonic transducer (CMUT) with a contoured electrode. In certain embodiments, the CMUT has a contoured electrode. The electrode may be non-planar to correspond to a deflected shape of the outer plate. A change in distance between the electrode and the plate after deflection may be greater than a minimum threshold across the width of the CMUT.
US11260419B2 Method for coating a structure with a fusion bonded material
The disclosure provides example methods and a system that includes: (a) a fluidization bed having a reservoir and comprising a base and a plurality of side walls, (b) an epoxy-based powder disposed within the reservoir, where the fluidization bed is configured to fluidize the epoxy-based powder, (c) a first heating element configured to heat the wire matrix reinforcement to at least a melting temperature, (d) a conveyor positioned over the fluidization bed and configured to engage the wire matrix reinforcement, where the conveyor is configured to submerge the wire matrix reinforcement into the fluidized epoxy-based powder such that a portion of the epoxy-based powder melts and coats the wire matrix reinforcement, and where the conveyor is configured to remove the wire matrix reinforcement from the epoxy-based powder; and (e) a second heating element configured to cure the epoxy-based powder coating the wire matrix reinforcement into a corrosion resistant barrier.
US11260418B2 Method for manufacturing target object coated with coating substance
A method for manufacturing a target object coated with a coating substance, whose edge face portions and flat face portion can be covered with the coating substance with a predetermined thickness, is provided. The target object T includes a flat face portion Tf and an edge face portion Te continuous from the portion Tf which includes a coating flat surface Tsp formed thereon which has a flat face. The portion Te includes a coating edge surface Tsc which includes at least one of a curved surface or a flat surface that is not parallel to the surface Tsp. The method includes a coating substance supply step of supplying the substance R along at least the surface Tsp, and an edge face portion coating substance adjustment step of adjusting the substance R supplied to the surface Tsc or moved from the surface Tsp to cover the surface Tsc at a predetermined thickness.
US11260417B2 Preform coating device
A preform coating device is provided with: a rotational holding part that horizontally holds a preform and rotates the preform about the axis of the preform, and that grasps a spout of the preform; a conveyance part that conveys the preform by moving the rotational holding part; a dispenser that discharges a coating liquid toward the preform; a preform support part that supports the bottom-side end of the cylindrical barrel of the preform while the dispenser is discharging the coating liquid; and a spout support part that supports the outer circumferential surface of the spout of the preform while the dispenser is discharging the coating liquid.
US11260414B2 Coating method and coating device
The present application discloses a coating method including: detecting a shape of an object over a coating zone which extends from a start point position to an end point position to generate first detection data before application of coating agent to the object; moving a bracket for holding a nozzle for discharging the coating agent with bringing the bracket into contact with the object to apply the coating agent to the object over the coating zone; detecting a shape of the object after application of the coating agent over the coating zone, to generate second detection data; extracting first extraction data and second extraction data in correspondence to detection positions intermittently set in the coating zone from the first detection data and the second detection data; and comparing the first extraction data with the second extraction data to detect a coating state of the coating agent.
US11260413B2 End effector for delivering material to a surface and associated system
An end effector, coupleable to a robot, for delivering a material to a surface, comprises a material applicator assembly, comprising a central shaft and an applicator co-rotatably coupled to the central shaft and configured to apply the material to the surface. The end effector also comprises a material supply carrier, comprising a base and a supply of the material coupled to the base. The material from the supply is feedable to the applicator. The end effector further comprises an actuator that rotatably couples the material supply carrier with the material applicator assembly. The actuator is operable to rotate the material supply carrier relative to the material applicator assembly.
US11260412B2 Fluid application device
A method and apparatus for applying a viscous fluid onto a surface. An applicator associated with an extension member may be positioned over the surface using a robotic operator. The extension member may be configured to maintain a selected distance between the applicator and a fluid source for the viscous fluid. The viscous fluid may be dispensed from the fluid source to the applicator. The viscous fluid may be applied onto the surface using the applicator.
US11260411B2 Autonomous painting robot
The present utility model relates to an autonomous interior painting robot for homes, commercial premises, hotels, etc. The robot is designed for painting and outlining while recognizing obstacles in the work area and aimed at reducing the efforts and time needed to carry out these operations. It is applicable in the field of interior design and the completion of small conditioning works. The autonomous painting robot comprises a mobile base (1) equipped with a paint tank and a pump or compressor, characterized in that the base (1) comprises a series of detectors configured to locate the base (1) and to detect obstacles, a substantially vertical lifting column (4), at the end of which a robot arm (5) is articulated and topped with a head (6) that carries a paint gun (7) connected to the pump, one or more cameras (9), and a proximity sensor (10).
US11260407B2 Methods and systems for a fuel injector assembly
Methods and systems are provided for injecting fuel through three different rows of injector nozzles, where each row of the injector nozzle is arranged along a different vertical plane of the injector body. In one example, an injector needle housed movably inside the injector body may supply high-pressure fuel to each of the rows of injector nozzles sequentially to deliver up to five fuel injections in one actuation cycle of the fuel injector. In another example, a fuel injector may include three injector needles, where movement of each injector needle inside a respective chamber of the fuel injector body may supply high-pressure fuel to the chamber from where the fuel may be injected through the coupled fuel injector nozzles.
US11260406B2 Injector
A nozzle assembly includes a body, a valve member, and a clamp member maintaining a flow director member against the body. The flow director member is sandwiched between the peripheral wall and the clamp member, and is provided with an outlet path including two distinct guidance channels extending from an upstream end and a common downstream end where is a spray hole. The outlet path creates impingement of the two flow streams flowing in the two channels before entering the spray hole.
US11260403B2 Centrifugal separator including noncontact seal and noncontact torque transfer mechanism, and centrifugal separation system containing the same
A centrifugal separator includes a rotating body driving and sealing structure in which a hermetically sealed space is formed between a rotating body and an outer case by sealing the inside and outside using a noncontact seal during rotation of the rotating body, in an airtight manner. A rotation coupling unit is provided at the upper end of a centrifugal cylinder, and even when the centrifugal cylinder is deformed during use causing an internal fluid to leak through a fitting portion of a bottom member to the centrifugal cylinder, the fluid leaks in the hermetically sealed space so that the driving system or the like is not contaminated.
US11260402B2 Electrostatic separation device, and associated separation method and use
An electrostatic separation device (is for a mixture of granules of different materials. The device includes a separation chamber having an inlet and delimiting an inner volume and a collection device for granules placed in the inner volume, opposite the inlet. At least two pairs of electrodes are successively placed in the elevation direction in the inner volume, between the inlet and the collection device. Each pair includes an anode and a cathode, placed on either side of a central axis extending in the elevation direction. At least one generating system is suitable for applying a difference in electric potential between the anode and the cathode of each pair.
US11260397B2 Device for granulating powders by cryogenic atomisation
A device for granulating powders by cryogenic atomisation, characterised in that it comprises: a device for mixing powders by cryogenic fluid, comprising at least one chamber for mixing powders, comprising a cryogenic fluid; and a device for atomising a suspension of powders mixed by the device for mixing powders in order to allow a granulation of the powders, comprising a way of fractionating the suspension of powders making it possible to adjust the size of the droplets of powders to be atomised, and a method for adjusting the moisture of the mixed powders and/or the moisture of the atomisation atmosphere.
US11260393B2 Digital PCR device and method using centrifugal force
A digital PCR device using centrifugal force. The present disclosure comprises: sample dish on which a microwell film having formed microwells is mounted; a door unit for inputting a sample while rotating the sample dish, and controlling the temperature of the sample which has been fractionated in the microwells by means of the centrifugal force and thus performing a PCR process; and a scan head unit for reading a fluorescent signal while rotating the sample which has been amplified in the microwells during the PCR process.
US11260387B2 Integrated purification and measurement of DNA methylation and co-measurement of mutations and/or mRNA expression levels in an automated reaction cartridge
Methods of determining methylation of DNA are provided. In one illustrative, but non-limiting embodiment the method comprises i) contacting a biological sample comprising a nucleic acid to a first matrix material comprising a first column or filter where said matrix material binds and/or filters nucleic acids in said sample and thereby purifies the DNA; ii) eluting the bound DNA from the first matrix material and denaturing the DNA to produce eluted denatured DNA; iii) heating the eluted DNA in the presence of bisulfite ions to produce a deaminated nucleic acid; iv) contacting said deaminated nucleic acid to a second matrix material comprising a second column to bind said deaminated nucleic acid to said second matrix material; v) desulphonating the bound deaminated nucleic acid and/or simultaneously eluting and desulphonating the nucleic acid by contacting the deaminated nucleic acid with an alkaline solution to produce a bisulfite converted nucleic acid; vi) eluting said bisulfite converted nucleic acid from said second matrix material; and vii) performing methylation specific PCR and/or nucleic acid sequencing, and/or high resolution melting analysis (HRM) on said bisulfite-converted nucleic acid to determine the methylation of said nucleic acid, wherein at least steps iv) through vi) are performed in a single reaction cartridge.
US11260381B2 Process for oligomerization
The invention relates to oligomerization of olefins, such as ethylene, to higher olefins, such as a mixture of 1-hexene and 1-octene, using a catalyst system that comprises a) a source of chromium b) one or more activators and c) a phosphacycle-containing ligating compound. Additionally, the invention relates to a phosphacycle-containing ligating compound and a process for making said compound.
US11260375B2 Process and catalyst for preparing 1,4-butanediol
The present invention relates to a process for preparing 1,4-butanediol (BDO) by hydrogenating 2-butyne-1,4-diol (BYD) or 4-hydroxybutanal (4-HBA) in the presence of a catalyst of the Raney type having a porous foam structure, wherein the macroscopic pores have sizes in the range of 100 to 5000 μm, and a bulk density of up to 0.8 kg/L.
US11260374B2 Cu-based catalyst, its preparation process and use thereof
The present invention relates to a Cu-based catalyst, a preparation process thereof and its use as the dehydrogenation catalyst in producing a hydroxyketone compound such as acetoin. Said Cu-based catalyst contains copper, at least one auxiliary metal selected from metal of Group IIA, non-noble metal of Group VIII, metal of Group VIB, metal of Group VIIB, metal of Group IIB and lanthanide metal of periodic table of elements, and an alkali metal, and further contains at least one ketone additive selected from a ketone represented by formula (II) and a ketone represented by formula (II′). Said Cu-based catalyst shows a high the acetoin selectivity as the dehydrogenation catalyst for producing acetoin. R1-C(═O)—CH(OH)—R2  (II) R1-C(═O)—CH(═O)—R2  (II′) In formulae (II) and (II′), each group is defined as in the description.
US11260373B2 Colloidal-copper based water oxidation electrocatalyst
A noble metal-free water oxidation electrocatalyst can be stable and obtained from earth-abundant materials, e.g., using copper-colloidal nanoparticles. The catalyst may contain nanobead and nanorod morphological features with narrow size distribution. The onset for oxygen evolution reaction can occur at a potential of 1.45 VRHE (η=220 mV). Such catalysts may be stable during long-term water electrolysis and/or exhibit a high electroactive area, e.g., with a Tafel slope of 52 mV/dec, TOF of 0.81 s−1, and/or mass activity of 87 mA/mg. The copper may also perform CO2 reduction at the cathode side. The Cu-based electrocatalytic system may provide a flexible catalyst for electrooxidation of water and for chemical energy conversion, without requiring Pt, Ir, or Ru.
US11260371B2 Selective catalytic reduction (SCR) catalyst comprising a composite oxide containing V and SB, preparation process thereof, and use thereof for nitrogen oxides removal
A catalyst composition comprising—a support comprising TiO2,—a composite oxide containing vanadium and antimony, which has a rutile-type structure different from VSbO4 and V0.92Sb0.92O4 as determined by X-ray diffraction (XRD) analysis with CuKα radiation, and—optionally, one or more selected from the group consisting of oxides of silicon, oxides of vanadium and oxides of antimony, for selective catalytic reduction of nitrogen oxides; to a process for preparing the catalyst composition, to the catalyst composition obtained/obtainable by the process and to use of the same for selective catalytic reduction of nitrogen oxides.
US11260370B2 Composition for exhaust gas purification, exhaust gas purifying catalyst containing same, and exhaust gas purifying catalyst structure
A composition for exhaust gas purification including first alumina including alumina containing lanthanum and second alumina including alumina containing lanthanum. The first alumina has a higher lanthanum content than the second alumina. The second alumina has a larger particle size than the first alumina. The lanthanum content of the first alumina is preferably 2 to 12 mass %, in terms of oxide, based on the total mass of alumina and lanthanum oxide of the first alumina. The lanthanum content of the second alumina is preferably 9 mass % or less, in terms of oxide, based on the total mass of alumina and lanthanum oxide of the second alumina.
US11260366B2 Method of obtaining inorganic sorbents for extraction of lithium from lithium-containing natural and technological brines
The invention provides a method of obtaining inorganic sorbents for extraction of lithium from lithium-containing natural and technological brines. The method consists of steps of obtaining six consecutive non-stoichiometric compound, wherein at the final step the sixth non-stoichiometric compound is obtained by converting the fifth non-stoichiometric compound into a hydrogen-form of inorganic ion-exchanger by treating the fifth non-stoichiometric compound with an acid solution. The method improves selectivity and exchangeability of sorbents to lithium based on manganese oxides, as well as chemical stability of the sorbents in cyclic operations.
US11260362B2 Removal of atmospheric pollutants from gas, related apparatuses, processes and uses thereof
One aspect of the invention relates to a method comprising a single-stage conversion of an atmospheric pollutant, such as NO, NO2 and/or SOx in a first stream to one or more mineral acids and/or salts thereof by reacting with nonionic gas phase chlorine dioxide (ClO20), wherein the reaction is carried out in the gas phase. Another aspect of the invention relates to a method comprising first adjusting the atmospheric pollutant concentrations in a first stream to a molar ratio of about 1:1, and then reacting with an aqueous metal hydroxide solution (MOH). Another aspect of the invention relates to an apparatus that can be used to carry out the methods disclosed herein. The methods disclosed herein are unexpectedly efficient and cost effective, and can be applied to a stream comprising high concentration and large volume of atmospheric pollutants.
US11260355B2 Apparatus for making content liquid foamy for discharge and systems and methods thereof
Systems, apparatuses, and methods for making content liquid foamy for discharge are described herein. A dispenser for making content liquid discharge foamy by mixing air flow from an air chamber with the content liquid flow from a liquid chamber can be provided. The dispenser can include a mixing chamber configured to mix air and content liquid; a porous member between an air passage from the air chamber and the mixing chamber; and a liquid passage from the liquid chamber to the mixing chamber. The liquid passage can have a first liquid passage and a plurality of second liquid passages. The liquid passage can be configured such that content liquid flows from the first liquid passage to the second liquid passages to the mixing chamber. The second liquid passages can be configured to provide flow of the content liquid in at least two directions.
US11260353B2 Systems and methods for treating viscous media
Systems for treating a viscous medium are illustrated. The systems may comprise a primary source of pressurized treatment fluid, a fluidic transfer assembly, and a helical mixing element. The fluidic transfer assembly comprises a fluidic transfer chamber and a fluid outlet. The primary source of pressurized treatment fluid is in fluidic communication with the fluid outlet of the fluidic transfer assembly via the fluidic transfer chamber. The primary source of pressurized treatment fluid is in fluidic communication with the fluid outlet of the fluidic transfer assembly via the fluidic transfer chamber. The helical mixing element comprises an interior treatment fluid passage and external injection ports. The fluid outlet of the fluidic transfer assembly is in fluidic communication with the external injection ports of the helical mixing element via the interior treatment fluid passage of the helical mixing element. The systems may be incorporated into methods for treating a viscous medium.
US11260347B2 Method and device for separating extracellular vesicles from biological liquids with the aid of cascade ultrafiltration
This invention describes a method and a device for efficient isolation of extracellular vesicles from animal and human biological fluids, as well as from culture fluid using equipment of standard diagnostic laboratories, that is, without the use of ultracentrifugation. These method and device can be applied for the diagnosis of various human diseases, as well as for therapeutic purposes, if the purified vesicles are used as an agent for drug delivery to the cells of the body. The device for the purification of extracellular vesicles contains at least two membrane filters: the first filter containing a membrane with pore sizes in the range from 400 to 600 nm, connected to the second filter containing a membrane with pores in the range from 95 to 200 nm. At the same time, the membranes of these filters are made of materials that practically do not bind biological polymers.
US11260346B2 Inerting system
A system is disclosed for providing inerting gas to a protected space. The system includes an electrochemical cell including a cathode, an anode separated by a separator that includes an ion transfer medium, and an electrical connection to a power source or power sink. A cathode fluid flow path is in operative fluid communication with a catalyst at the cathode between a cathode fluid flow path inlet and a cathode fluid flow path outlet, and an anode fluid flow path is in operative fluid communication with a catalyst at the anode, and includes an anode fluid flow path outlet. A cathode supply fluid flow path is disposed between the protected space and the cathode fluid flow path inlet, and an inerting gas flow path is in operative fluid communication with the cathode flow path outlet and the protected space.
US11260345B2 High-efficiency desiccant wheel
A desiccant wheel is provided to be rotatable. Through the body of the wheel or a surface adsorbent, water vapor in humid air flow is adsorbed. By passing a high-temperature air flow through the wheel, the body or surface coating is regenerated with moisture removed. Along a cross-section radial, the wheel is divided into different areas. The body has three-dimensionally inter-connected pores. The pores can be of different types. The wheel is a complete concentric cylinder or a concentric cylinder comprising equal or unequal sectors. The equal or unequal sectors are separated with each other. The wheel can rotate at a fixed speed for continually repeating a process of adsorbing, transiting, and regenerating. Thereby, drying can be carried out without causing physical or chemical change to heat-sensitive material, which also improves drying efficiency, reduces size, lowers power consumption, and helps in carbon reduction for industry.
US11260332B2 Product gas filter
A product gas filter with a filter housing, into which product gas of a wood gas reactor is supplied, by means of a product gas line, and is discharged as clean gas through a clean gas line. Long-chain hydrocarbons in the product gas stream can be at least substantially reduced, and a high filter performance achieved, where the filter is divided gas-tight into two parts by a separating tray in such a way that the product gas line is delivered to the lower region and the clean gas line exits from the upper collecting space; at least two filter cartridges, each coupled individually to a compressed air line and compressed air source, project into the lower region; and a zeolite container is connected to the lower portion of the filter via a compressed air source connectable, Venturi nozzle and a lockable line.
US11260331B2 Air cleaner assemblies
A filter cartridge configured to be removably positionable within an inner opening of a housing, wherein the filter cartridge includes a media pack having an inlet end, an outlet end, and an outer surface having an outer peripheral shape, at least one of: (a) a frame member at least partially surrounding the media pack, the frame member including a frame wall having a shape that is different from the outer perimeter shape of the media pack; and (b) a shell at least partially surrounding the media pack, the shell including a shell wall having a shape that is different from the outer perimeter shape of the media pack, and a sealing member extending at least partially around the inlet end of the media pack, wherein the sealing member connects the media pack to at least one of the frame member and the shell.
US11260325B2 Filtering device for removing impurities in a mixture of biological diatomite
The present invention discloses a filtering device used for removing impurities in a mixture of biological diatomite, which relates to the technical field of sewage treatment. This device includes a plurality of deflectors evenly distributed in multiple layers in the vertical direction. Each deflector includes a shell and a top plate. There is a filter unit symmetrically arranged on the left and right sides of each deflector. The top of the shell is covered with a top plate hinged with the depressed plate. The bottom of the shell is provided with water inlets which communicate with the shunt pipe, and the upper parts of the left and right side walls of the shell are provided with overflow ports. The shell also has a plurality of diversion folding plates located below the overflow ports and vertically staggered and distributed on the left and right side walls. The filter unit includes an inclined water guiding groove and a filtering plate.
US11260319B2 Solid phase extraction method using micro device
The present invention provides a solid phase extraction method using a micro device having a dam forming portion including a dam, the solid phase extraction method comprising the steps of: (i) injecting a solvent and a filler into the micro device, moving the solvent to the dam forming portion, the dam allowing the solvent to flow therethrough and preventing the filler from passing therethrough, and adsorbing a material to be separated onto the filler in the dam forming portion; and (ii) extracting, from the filler, the adsorbed material, wherein the micro device is rotated with respect to a central axis during one of steps (i) and (ii), and the rotation of the micro device is performed at an angular velocity defined by equation 1.
US11260311B2 Resistance control systems and methods for amusement attractions
A resistance control system for a passenger support of an amusement attraction includes a first foundation, a second foundation, and a support extending between the first foundation and the second foundation. The second foundation is pivotably coupled to the support at a pivot joint. The resistance control system also includes a motor and a linkage system coupled to the motor and to the second foundation such that the motor is configured to output a torque to adjust, via the linkage system, a resistance to movement of the second foundation about the pivot joint and relative to the first foundation.
US11260306B2 Matchmaking for online gaming with simulated players
A matchmaking system matches players for online gaming, when some of the players may be human players and others may be simulated players. The matchmaking system may determine a first skill score associated with a first player for an online game, determine a behavior simulation model for a simulated player is available for the online game, determine a second skill score associated with the behavior simulation model for the online game, and determine the behavior simulation model matches with the first player based at on the first skill score being within a threshold of the second skill score. The matchmaking system may then instantiate a simulated player based on the behavior simulation model and instantiate the online game with the first player and the simulated player.
US11260303B2 Method and apparatus for adjusting attributes of object, storage medium, and electronic device
Embodiments of the present disclosure disclose a method and an apparatus for adjusting attributes of an object, a storage medium, and an electronic device. The method includes: displaying, by a terminal, target prompt information in a target interface of a client as a target scene is run on the client, the target prompt information being used for prompting the adjustment of the attributes of a virtual control object controlled by a player in the target scene; determining, by the terminal according to preset configuration information of the target scene, an adjustment mode of performing adjustment; and automatically adjusting, by the terminal, the attributes of the virtual control object in a case that the determined adjustment mode is an automatic adjustment mode. The embodiments of the present disclosure solve the technical problem that it is insufficiently flexible to adjust the attributes of a virtual control object in the related art.
US11260302B2 Apparatus and method of creating agent in game environment
An agent creating method of creating an agent in a game environment is provided. The agent creating method includes creating, by an agent creating apparatus, a base agent on the basis of a common action characteristic pattern of players to transfer the base agent to the game server, receiving, by the agent creating apparatus, match result data obtained by performing a match between the base agent and a character of an individual player, and performing, by the agent creating apparatus, machine learning by using the match result data and creating an evolved agent customized for matchmaking of the individual player on the basis of a result of the machine learning.
US11260299B2 Object viewability determination system and method
A system for calculating viewability scores of objects displayed within a viewport, the system comprising a processing resource configured to perform the following for at least one object of the objects: determine a first value indicative of a relative portion of the object from the viewport; and calculate a viewability score of the object, wherein the viewability score is calculated based on the first value.
US11260292B2 Gaming device and gaming controller
A gaming device includes a self-stabilizing module including a first portion and a second portion, a controller assembly disposed at the second portion, a motion sensor, an operation processing module, and a display screen disposed at the first portion. The operation processing module generates a frame signal to the display screen according to a program. The controller assembly and the second portion rotate about at least one self-stabilizing axis relative to the first portion when the self-stabilizing module is activated. The motion sensor generates a control signal due to the relative rotation of the first and second portions. The operation processing module generates another frame signal corresponding to a movement posture of the controller assembly relative to the display screen according to the control signal and the program. The display screen is not located on a movement track of the controller assembly. A gaming controller is also provided.
US11260291B2 Information handling system and detachable game controller
A game controller has first and second controller housings that detachably couple to an information handling system and a bridge to communicate inputs by plural input devices directly with the information handling system or indirectly by communicating with the bridge so the bridge communicates with the information handling system. The information handling system operates in a handheld mode with game controller input devices, such as joysticks and triggers, coupled for use at opposing sides of the information handling system housing, or in a standalone mode with the game controllers detached from the information handling system and attached to a bridge so that the bridge communicates the controller inputs to the information handling system. Attachment of a game controller to a bridge or information handling system is aided with opposing polarity magnets at proper alignment. If a game controller attempts to couple to an opposite of an intended side, like polarity of the magnets repel the game controller from the bridge or information handling system.
US11260288B2 Disassemblable information handling system game controller
A game controller has first and second controller housings having an attachment guide structure that detachably couples to an attachment tab structure disposed on opposing sides of an information handling system and a bridge. Input devices of the controller housing communicate directly with the information handling system through opposing pins and pads disposed in the attachment features or indirectly by communicating with the bridge through opposing pins and pads so the bridge communicates with the information handling system. The attachment guide structure has opposing lips with plural slots that pass tabs of the attachment tab structure through so that a sliding motion engages the tabs behind the lips. Magnets of opposing polarity repel attachment attempts when a game controller attempts to attach to an opposite side of an information handling system or bridge housing from that which the game controller is intended to attach, such as a left side controller attached to a right side of a bridge or information handling system.
US11260286B2 Computer device and evaluation control method
A computer device evaluates an input timing at which a player performed an operation input. The player holds a controller containing sensors for measuring acceleration and angular speed and performs a motion of shaking and stopping the controller. The computer device is communicably connected to the sensors. The computer device determines the input timing by detecting a peak of a measurement value that appears immediately before the stop of the motion. Then, the computer device performs the evaluation based on a difference between the determined input timing and a reference timing.
US11260283B2 Article moveable between two positions and a method of combining two or more of the same
An article is moveable between a first position and a second position and biased to the second position. The article is retained in the first position by retaining means until a predetermined condition is met and when met, the biasing means are released to move the article from the first position to the second position. The predetermined condition is met when at least one formation of a plurality of formations located with respect to at least one face of the article is moved from a first position to a second position, thereby releasing the retaining means. The article further includes user selection means to allow the user to select which one, or combination, of the plurality of formations, when moved, will cause the release of the retaining means.
US11260275B2 Golf club head and method of manufacturing same
A golf club head 1 has a first wall portion comprising a first member made of first material, a second member made of second material, and a third member made of material. The third material's specific gravity is different from the first material's specific gravity and second material's specific gravity. The weldability between the first material and second material is superior to the weldability between the first material and third material. The first member is fixed to the second member by welding. The third member is fixed to the first member by using the second member. The third member comprises a portion continuous from a first surface to an opposite second surface of the first wall portion in the thickness direction of the first wall portion.
US11260273B2 Device for displaying in response to a sensed motion
A device includes a signaling means and a motion sensor, and logic for activating or controlling the signaling means in response to a sensed motion according to an embedded logic. The device may be used as a toy, and may be shaped like a play ball or as a handheld unit. It may be powered from a battery, either chargeable from an AC power source directly or contactless by using induction or by converting electrical energy from harvested kinetic energy. The embedded logic may activate or control the signaling means, predictably or randomly, in response to sensed acceleration magnitude or direction, such as sensing the crossing of a preset threshold or sensing the peak value. The visual means may be a numeric display for displaying a value associated with the count of the number of times the threshold has been exceeded or the peak magnitude of the acceleration sensed.
US11260272B2 System and method of use for swimmer wings
A system and method for two swimmer wings designed using biomimicry and inspired by winged creatures/birds of flight as well as the fore flippers of a sea turtle. The swimmer wings are designed for users to traverse long distances instead of relying on personal watercrafts or boats to not only help sustain the environment by reducing the carbon footprint but also provide physical exercise to improve the user's well-being. The swimmer wings include a board, an arm guard which shields the user's forearm, and arm fasteners that secure the user's forearm between the board and the arm guard.
US11260271B2 Stretchable cover for exercise device and/or equipment
A removable stretchable cover for exercise equipment has a first wall, a second wall, two side walls and two end walls arranged to form an interior cavity and an opening through which the exercise equipment is appointed to traverse. The opening is formed as a stretchable slit opening adapted to expand to engulf the exercise equipment, and contract in a closed configuration when the exercise equipment is housed within the interior cavity to substantially enclose the equipment within the cover. At least one anti-slip surface is integrated within at least one of the first wall, second wall, two side walls or two end walls. The cover is composed of a thin, stretchy, soft material so that it can be significantly stretched and contracted to snuggly fit over the exercise equipment. Examples of exercise equipment for which the cover is especially well suited include yoga blocks, foam rollers, exercise balls and arm handles of exercise machines.
US11260269B2 Exercise apparatus
An apparatus for an exercise task includes a pneumatic arrangement, which includes a pressure source, a pneumatic controller, pneumatic transfer channels, and at least one pneumatic resistor element, which includes a pneumatic cylinder with its piston. The apparatus additionally includes a mechanical lever arm structure or another mechanical connecting structure, which is for a user's limb contact and which is at a second end connected to the pneumatic resistor element. The apparatus additionally includes a sensor structure, a calculation arrangement and a display. The sensor structure is arranged to measure at least one measurement quantity of the exercise task and, based on the measurement, the calculation arrangement is arranged to form information on the display of the apparatus, regarding the power and/or force and/or range of motion of the exercise task. In the invention, regardless of the number of pneumatic resistor elements, the sensor structure includes one pressure sensor only, and to compensate for the small number of sensors, the calculation arrangement includes a correlation-taught calculation unit, which comprises a correlation algorithm taught with a larger number of sensors than the number of sensors in the apparatus, concerning the correlation between power and/or force and/or range of motion of the exercise task and the measured information.
US11260268B1 Systems, methods, and apparatus for isometric, isokinetic, isotonic, and isodynamic exercise
A scientifically controlled exercise based on a measurement of maximum voluntary contraction (MVC). A mechanical apparatus includes a sensor, an actuator, and a processor. The apparatus receives a mechanical exertion from a user while the processor receives signals from the sensor and sends signals to the actuator to control the mechanical apparatus. The processor measures a MVC exerted by a user and determines a protocol for the exercise based on the measured MVC. The protocol includes a specified exertion to be performed by a user, the specified force and velocity profile governing the exertion, and a specified sequence of repetitions of the exertion, spaced by rest periods. The protocol includes real-time feedback to the user related to compliance with the protocol. The methodology and equipment described herein provides users a safe and effective means of improving muscular strength or endurance and ameliorating various neurological or physiological conditions.
US11260265B2 Stationary bike
A stationary bike includes a flywheel mounted to a frame, and a chair coupled to the frame, the chair having a first, a second and a third section each having a flat area, wherein the flat area of the first section is substantially horizontal for supporting a user's buttocks when the user is in a sitting posture, the flat area of the second section forms a first angle to a vertical plane for the user's lower back to lean against when in the sitting posture, and the flat area of the third section forms a second angle to the vertical plane which is larger than the first angle, when the user's upper back rests on the third section, the user's lower back and buttocks are raised above the second section and the first section, respectively.
US11260263B2 Spine corrector having adjustable handles
A Pilates spine corrector having a user-adjustable handle assembly that rotates. The handle assembly has a grip bar that is eccentrically positioned such that it is off centered.
US11260262B2 Portable resistance workout apparatuses and systems
A portable strength training apparatus, system and method. The apparatus can include a platform base having a top surface, a bottom surface, and a plurality of base attachment mechanisms. One or more of the plurality of base attachment mechanisms can be removably coupled to a resistance band. A force sensor can be coupled to the resistance band, the force sensor comprising a force transducer that can include electronic circuitry to track, record, and analyze resistance forces applied to the resistance band.
US11260259B2 Weight plate
A weight plate that is comprised of multiple parts that connect to each other around the handle of a progressive resistive device.
US11260258B2 Dumbbell with rotating grip
A dumbbell having a shaft, first and second dumbbell heads, respectively fixedly connected to first and second ends of the shaft, a tube-shaped hollow grip rotatably arranged around the shaft having first and second ends. An inner diameter of the grip is greater than an outer cross-sectional dimension of the shaft. The dumbbell further having a first ball bearing and a second ball bearing, wherein an outer ring of the first ball bearing is connected to the first dumbbell head, and an inner ring of the first ball bearing is fixedly arranged to the first end of the hollow grip, and an outer ring of the second ball bearing is connected to the second dumbbell head, and an inner ring of the second ball bearing is fixedly arranged to the second end of the hollow grip.
US11260251B2 Respirator device with light exposure detection
A system including a head-mounted device having a face shield; a respirator coupled to or embodied in the head mounted device; a light having a light intensity; a light detector, and a computing device communicatively coupled to the at least one light detector that receive from the light detector data indicting a type and intensity of light, and determine that the light matches a particular type of light and whether it exceeds a threshold, and on the basis of this determination, modifies the intensity of the light.
US11260246B2 Apparatus and methods for magnetic control of radiation electron beam
Apparatus and methods for controlling a radiotherapy electron beam. Exemplary embodiments provide for focusing the electron beam at different depths by altering parameters of a plurality of magnets. Exemplary embodiments can also provide for focusing the electron beam at different depths while maintaining the energy level of the electron beam at a consistent level.
US11260245B2 System and method for determining arc dose for arc therapy
Systems and methods are provided for radiation delivery. An exemplary method includes receiving an image depicting anatomical data of a target region of patient tissue and determining an initial prescribed dose of radiotherapeutic radiation to be delivered to the target region. The method also includes discretizing the arc for VMAT into a plurality of arc segments and performing an iteration process for determining an arc dose according to radiation delivered in the arc segments. The method further includes determining whether a condition for terminating the iteration process is met and terminating the iteration process based on a result of the determination that the condition for terminating the iteration process is met.
US11260244B2 Surgically positioned neutron flux activated high energy therapeutic charged particle generation system
A process for treating highly localized carcinoma cells that provides precise positioning of a therapeutic source of highly ionizing but weakly penetrating radiation, which can be shaped so that it irradiates essentially only the volume of the tumor. The intensity and duration of the radiation produced by the source can be activated and deactivated by controlling the neutron flux generated by an array of electrically controlled neutron generators positioned outside the body being treated. The energy of the neutrons that interact with the source element can be adjusted to optimize the reaction rate of the ionized radiation production by utilizing neutron moderating material between the neutron generator array and the body. The source device may be left in place and reactivated as needed to ensure the tumor is eradicated without exposing the patient to any additional radiation between treatments. The source device may be removed once treatment is completed.
US11260242B2 Systems and methods for use in treating sensory impairment
Methods and systems for use in treating one or more patient's sensory impairment, e.g., associated with peripheral neuropathy. An exemplary system may be configured to generate treatment information for treating sensory impairment in at least one body portion using photonic energy from a therapeutic laser based on data indicative of damage.
US11260238B2 Wearable medical device (WMD) implementing adaptive techniques to save power
A wearable cardioverter defibrillator (WCD) comprises a plurality of electrocardiography (ECG) electrodes and a plurality of defibrillator electrodes to contact the patient's skin when the WCD is delivering therapy to the patient, a preamplifier coupled to the ECG electrodes to obtain ECG data from the patient. a processor to receive the ECG data from the preamplifier, and a high voltage subsystem to provide a defibrillation voltage to the patient through the plurality of defibrillator electrodes in response to a shock signal received from the processor. In a first power mode of a range of power modes the preamplifier is configured to perform low-fidelity ECG acquisition and the processor is configured to perform simple arrythmia detection analysis, and in a second mode of the range of power modes the preamplifier is configured to perform high-fidelity ECG acquisition and the processor is configured to perform complex arrythmia detection analysis.
US11260233B2 Techniques for heart muscle remodeling using a cardiac pacemaker and related systems and methods
According to some aspects, a cardiac pacemaker for implantation within a subject is provided, the pacemaker including a housing, at least one sensor configured to detect an activity level of the subject, and at least one processor coupled to the sensor configured to detect inactivity of the subject based on output from the at least one sensor, produce a first signal configured to increase the heart rate of the subject to a first heart rate during a first time period, wherein the first heart rate is above a resting heart rate and below 100 beats per minute, and in response to determining that the first time period has elapsed, producing a second signal configured to increase the heart rate of the subject to a second heart rate during a second time period, wherein the second heart rate is between 100 and 140 beats per minute.
US11260232B2 System, method, and device for providing feedback to a patient during electrical stimulation
Feedback regarding electrical stimulation is provided to a patient. Electrical stimulation is applied to the patient. The electrical stimulation is applied by varying an electrical stimulation parameter. A signal is communicated to the patient via an electronic device. The signal is correlated with the electrical stimulation parameter such that the signal varies in association with the varying of the electrical stimulation parameter. The communicating is performed while the electrical stimulation is applied. Feedback is received from the patient in response to the electrical stimulation. Based on the received feedback from the patient, the electrical stimulation is adjusted.
US11260231B2 Electrical stimulation modulation
Techniques, systems, and devices are disclosed for delivering stimulation therapy to a patient. In one example, a medical device determines a first set of stimulation parameters that define entrainment stimulation pulses configured to entrain electrical activity in a patient. The medical device may control a stimulation generator to generate the entrainment stimulation pulses according to the first set of stimulation parameters. The medical device may further determine a second set of stimulation parameters that define at least one desynchronization stimulation pulse configured to disrupt at least a portion of the electrical activity entrained by the entrainment stimulation pulses. The medical device may subsequently control the stimulation generator to generate the desynchronization stimulation pulse(s) according to the second set of stimulation parameters.
US11260229B2 Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
Disclosed are apparatuses and methods for reducing or limiting blood loss and reducing bleed time in a subject by combined vagus and trigeminal stimulation. The apparatuses and methods may activate (e.g., electrically) one or more branches of the trigeminal nerve and may concurrently (at overlapping or near-overlapping time) independently activate the vagus nerve. This activation may be invasive or non-invasive.
US11260228B2 Wearable device with tragus modulation system
A wearable device combines its existing functions (e.g., a headphone) with non-invasive autonomic modulation using tragus or other external auditory meatus stimulation. The wearable device can output audio to a user, such as music, podcast, etc., and further provide modulation of the vagus nerve via tragus stimulation or other external auditory meatus stimulation to treat various diseases.
US11260226B2 Cochlear implant assemblies and methods of manufacturing the same
An exemplary cochlear implant assembly includes a cochlear implant configured to apply electrical stimulation to the recipient by way of an electrode array, a cochlear implant antenna communicatively coupled to the cochlear implant, and an encapsulant that covers the cochlear implant and the cochlear implant antenna, the encapsulant impregnated with a dielectric material that is configured to confine an electric field around the cochlear implant antenna. Corresponding methods for manufacturing cochlear implant assemblies are also described.
US11260224B2 Deep tissue pulsed electromagnetic field therapy apparatus and method of use thereof
The invention comprises a method and apparatus for delivering electrons to skin of a person, comprising the steps of: (1) attaching a longitudinal length of a flexible electrically conductive tape to the skin of the person, the flexible electrically conductive tape comprising: an electrically conductive strip and an adhesive layer, the adhesive layer comprising a top surface and an adhesive surface, (2) the adhesive surface affixing the electrically conductive strip to the skin, where the adhesive layer comprises a set of apertures therethrough to form longitudinally distributed electrical contact points along a length of the electrically conductive strip; and (3) an energy source delivering electrons, under control of an electrical control circuit of a controller, to the electrical contact points of the flexible electrically conductive tape.
US11260223B2 Low-frequency treatment device and treatment system
A low-frequency treatment device and a treatment system with enhanced user convenience. An acquisition unit acquires an atmospheric pressure of a position where the low-frequency treatment device is located (step S102), a determination unit determines whether the atmospheric pressure is less than a threshold (step S104), and a treatment portion increases an intensity of low frequency treatment if the atmospheric pressure is less than the threshold (step S108).
US11260220B2 Implantable cochlear system with integrated components and lead characterization
Cochlear implant systems can include a signal processor, an implantable battery and/or communication module, and a plurality of conductors coupling the implantable battery and/or communication module and the signal processor. The implantable battery and/or communication module can communicate data and deliver electrical power to the signal processor via the plurality of conductors. The implantable battery and/or communication module can be configured to perform characterization process to determine one or more characteristics of one or more such conductors. Characterization processes can include determining an impedance between two conductors as a function of frequency, determining whether a conductor is intact, and determining an impedance of a given conductor. Some characterization processes include grounding one or more conductors.
US11260218B2 Medical therapy arrangement for applying an electrical stimulation to a human or animal subject
A garment worn by the patient is provided. The garment has a first module electrically connected to a second module. The first module has a first sub-control unit electrically connected to a first electrode and a second electrode placed at a first muscle and a third electrode and a fourth electrode placed at a second muscle. The sub-control unit is electrically connected to a master unit. The first muscle is stimulated with a first stimulation signal without shortening the first muscle by sending the first stimulation signal to the first electrode placed. The stimulation of the first muscle relaxes the second muscle.
US11260216B2 Methods and systems for detecting atrial contraction timing fiducials during ventricular filling from a ventricularly implanted leadless cardiac pacemaker
A ventricularly implantable medical device that includes a sensing module that is configured to detect an artifact during ventricular filling and to identify an atrial event based at least on part on the detected artifact. Control circuitry of the implantable medical device is configured to deliver a ventricular pacing therapy to a patient's heart, wherein the ventricular pacing therapy is time dependent, at least in part, on the identified atrial event.
US11260208B2 Dilation catheter with removable bulb tip
An apparatus includes a shaft, an expandable dilation member, and a bulbous tip. The shaft has a first outer cross-sectional dimension. The dilation member is positioned proximal to the distal end of the shaft. The dilation member is operable to transition between a non-expanded configuration and an expanded configuration. The dilation member is sized to pass through a passageway associated with drainage of a paranasal sinus or a Eustachian tube when the dilation member is in the non-expanded configuration. The bulbous tip is positioned at the distal end of the shaft. The bulbous tip is distal to the dilation member. The bulbous tip has a second outer cross-sectional dimension. The second outer cross-sectional dimension is larger than the first outer cross-sectional dimension. The bulbous tip is removably secured to the distal end of the shaft.
US11260207B2 Catheter valve
The present invention relates to a catheter valve for use with a catheter. The catheter valve comprises an inlet nozzle at a front end of the valve and an outlet nozzle at a rear end of the valve. The valve comprises a longitudinal stem encapsulated within a middle section of the valve which extends in between the front end and the rear end of the valve. The longitudinal stem is divided into a front end and a rear end by a rib and an O-ring is inserted into the front end of the stem; and a resilient means is inserted into the rear end of the stem; the front end of the longitudinal stem further comprises sectional longitudinal grooves which cuts across the longitudinal and cylindrical stem extending from a head end of the front end of the stem up till the rib of the stem and the head end is curved inwardly in between each sectional longitudinal groove; and the rear end of the longitudinal stem further comprises sectional longitudinal grooves which cuts across the longitudinal and cylindrical stem in a triangular form extending from a head end of the rear end of the stem up till a bottom interface of the rib.
US11260206B2 Insertion device for one-handed insertion of a guidewire into the lumen of a vessel/cavity
A device for one-handed insertion of a guidewire into a vessel or cavity is provided. The device has a body, an actuator carriage, a guidewire feed, and a syringe. The body has a handle, a guideway, and a clip to retain the syringe. The syringe has a barrel and a plunger with a flange and a guidewire passage. The actuator carriage has a trigger and a clip to grasp the syringe plunger flange. The actuator carriage slides along the body guideway. The guidewire feed has a wire feed surface. The thumb engages wire at the wire feed surface to advance and retract the wire through the guidewire passage and a finger moves the trigger to move the syringe plunger rearwardly and/or forwardly, while the remaining fingers of the one hand grasp the handle. The device allows the user to sense resistance encountered by the tip of the wire.
US11260199B2 Layered yarn and weighted blanket for deep pressure therapy
Disclosed is a weighted material that is configured to effectuate deep pressure therapy to a person when the weighted material is used as a blanket over the person's body. A length of layered yarn is interlooped to form the weighted material. The layered yarn includes an outer tube extending longitudinally from a first end to a second end. The outer tube defines a conduit extending longitudinally therethrough from the first end to the second end. A fiber material is disposed within the conduit and extend longitudinally from the first end to the second end. The interlooped length of yarn, by itself, is configured and sufficiently weighted to effectuate deep pressure therapy to a person when the blanket lies over the person's body. Various other systems and methods are also disclosed.
US11260188B2 Ultrasound scanning apparatus, breathing machine, medical system and related method
An ultrasound scanning apparatus comprises an ultrasound scanning unit, an ultrasound controller for controlling the operation of the ultrasound scanning unit, detecting the operation state of the ultrasound scanning unit, generating a first enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from an operating state to a non-operating state and generating a second enable signal when detecting that the operation state of the ultrasound scanning unit is transferred from the non-operating state to the operating state, and an enable output end for transmitting the first enable signal or the second enable signal to the breathing machine to control the running of the breathing machine.
US11260187B2 Breathable gas supply apparatus
A CPAP device for delivering pressurized, humidified breathable gas for a patient includes a flow generator configured to pressurize a flow of breathable gas. The flow generator includes an air outlet and a removable water container configured to humidify the pressurized breathable gas received from the flow generator. The water container includes an air inlet and an air outlet. The CPAP device further includes a first elastomeric face seal configured to sealingly abut against a substantially flat portion of the water container surrounding the water container air inlet, the first elastomeric face seal being located at an intermediate position between the flow generator air outlet and the water container air inlet when the water container is placed into position to pneumatically communicate with the flow generator. In addition, the CPAP device includes a second elastomeric face seal, a portion of which is configured to sealingly abut against a substantially flat external surface portion of the water container surrounding the water container air outlet.
US11260182B2 Chemical liquid injector, method for controlling chemical liquid injector, and computer program
A chemical-liquid injector includes a piston-driving mechanism (130) that moves a piston member of a syringe containing a contrast medium, which includes an actuator and a ram member which is moved back and forth by the actuator, a control circuit (150) which is electrically connected to the actuator, and an operating knob unit (170) which includes an operating knob that is to be operated by an operator, and a rotation sensor that outputs an electric signal corresponding to a rotation of the operating knob. The control circuit is configured to generate a predetermined control signal accordingly, on the basis of a signal from the rotation sensor, and the piston-driving mechanism is operated according to the control signal.
US11260179B2 Multi-functional syringe plunger and method of use
A fat-harvesting syringe having a multi-functional plunger assembly. The plunger assembly comprises an outer plunger rod body, an inner central plunger rod and a piston seal assembly. The outer plunger rod body having a first and a second end. The first end having a central lumen all at its finger grip handle and at the second end having flanges that are expandable. Once the central plunger inner rod is inserted fully into central lumen of plunger rod body, the expandable flanges expands and engages with the piston seal assembly. Also when the inner plunger rod is retracted, the plunger body flanges retract back and disengages from piston seal assembly.
US11260174B2 Ambulatory medical device data access management via wireless wide area network
Systems and methods presented herein relate to managing ambulatory medical device data access. A computing system of a networked computing environment can establish a direct end-to-end data connection to an ambulatory medical device via a wireless wide area network. A public key of the computing system may be transmitted to the ambulatory medical device permitting the ambulatory medical device to encrypt data to be transmitted to the computing system. The computing system may receive, via the direct end-to-end data connection, encrypted data from the ambulatory medical device, and upon decrypting the data can generate a therapy report based at least in part on the therapy data. This therapy report may include time-series therapy data relating to the therapy delivered by the ambulatory medical device over a particular time period. The computing system can restrict access to the therapy report to authorized users.
US11260169B2 Infusion pump system and methods
Some embodiments of an infusion pump system can provide an alarm and user instructions in response to an ambient air pressure change or ambient air temperature that exceeds an alarm limit parameter. In some circumstances, the infusion pump system can be configured to monitor the actual ambient air pressure and temperature around the infusion pump system.
US11260167B2 Automatic fluid product injection device
An automatic fluid injection device comprising: a base body (1) for coming into contact with an injection zone; a support assembly (2) for supporting an actuator mechanism (5, 6, 7) that is controlled by power supply means (11); at least one fluid reservoir (3), each containing an injection piston (35), arranged in said base body (1); a needle assembly (100) comprising an insertion actuator (8), needle movement means (9, 9′), a priming needle (101) for associating with each reservoir (3) and for penetrating into said reservoir (3) before moving its piston (35), and an injection needle (102) for penetrating into the injection zone and for injecting the contents of said reservoir(s) (3) into said injection zone, said device including at least one actuator button (200) for priming, inserting the injection needle into the injection zone, administering fluid, and then retracting the injection needle.
US11260166B2 Anti-reflux tube-type enemator
Disclosed are various embodiments for an anti-reflux tube-type enemator that is leakproof, easy-to-clean, and quickly inflates to provide a steady flow of solution. The anti-reflux enemator includes a nozzle comprising a nozzle outlet, a tube fluidly coupled to the nozzle, and an enema bulb fluidly coupled to the tube. The enema bulb is configured to store solution therein and, in response to a squeezing force applied to the enema bulb, direct the solution through the tube and the nozzle, and expel the solution through the nozzle outlet. An anti-reflux coupler is positioned between the enema bulb and the tube through which the solution passes from the enema bulb to the tube. One or more one-way air valves are positioned relative to an aperture of the enema bulb.
US11260153B2 Home renal therapy machine
A renal therapy system is disclosed. In an example, a renal therapy system includes a dialysis fluid pump, a control processor for controlling a treatment performed by the dialysis fluid pump, and a user interface device in operable communication with the control processor.
US11260152B2 Apparatus for collecting breast milk
Apparatuses for collecting breast milk are described herein. The apparatuses include a body having a front side and a rear side opposed to the front side, the body defining a cavity and the rear side defining an opening shaped for receiving a portion of a user's breast. The cavity has an upper region for receiving the portion of the user's breast and a lower region for collecting the breast milk. The opening is positioned adjacent to the upper region of the cavity. The apparatuses may include a suction generating device for modulating the negative pressure in the cavity when the apparatus is pressed against the user's breast.
US11260149B2 Hydrogel for cartilage tissue regeneration
A method for cartilage tissue engineering including fabricating a nanocomposite, injecting the nanocomposite into a defect site of cartilage, and forming a hydrogel in the defect site of the cartilage using a sol-gel transition responsive to increasing temperature of the nanocomposite from room temperature to 37° C. Fabricating a nanocomposite includes forming an activated copolymer by functionalizing a copolymer, forming a conjugated copolymer by grafting the activated copolymer to a polysaccharide, forming a protein-conjugated copolymer by crosslinking a protein with the conjugated copolymer, forming the nanocomposite by adding a plurality of nanoparticles to the protein-conjugated copolymer.
US11260144B2 Two-paste cement-forming compositions
Injectable, ready-to-use two-paste cement-forming compositions comprise a first paste and a second paste. The first paste comprises a non-aqueous oil-based suspension of monocalcium phosphate monohydrate (MCPM) powder, at least one surfactant effective to improve compatibility of the oil and the MCPM, and an organic acid, with an oil to MCMP powder weight ratio of about 0.2 to about 0.5. The second paste comprises an aqueous suspension of β-tricalcium phosphate (β-TCP) powder and a gel-forming polymer, with a water to β-TCP powder weight ratio of about 0.3 to about 0.5. The molar ratio of β-TCP powder to MCPM powder is greater than 1. An article of manufacture comprises a first compartment in which the first paste is contained, and a second compartment in which the second paste is contained. The compositions are useful for bone repair or replacement.
US11260127B2 Mesoporous silica nanoparticles for diagnostic and therapeutic applications
A system for delivering a therapeutic agent to cell or tissue of a subject includes a mesoporous silica iron oxide nanoparticle with one or more therapeutic agents that are contained in a mesoporous silica layer of the nanoparticle and a remote radiofrequency (RF) energy source for applying RF energy to the nanoparticle effective to release the one or more therapeutic agents from the nanoparticle by mechanical tumbling and/or vibration of the nanoparticle, wherein release of the one or more therapeutic agents not caused by a hyperthermic response of the nanoparticle to the RF energy.
US11260126B2 Acoustic driven drug delivery systems
The present invention provides acoustically activated liposome compositions for use as drug delivery vehicles, and to methods for drug release and drug delivery for therapeutic applications.
US11260125B2 Anti-IL31RA antibody-containing formulations
In one non-limiting embodiment, the present disclosure relates to lyophilized formulations containing an IL-31 antagonist (for example, an anti-IL-31RA antibody) as an active ingredient, the lyophilized formulations further containing arginine and/or a salt thereof and sucrose and/or trehalose. In another non-limiting embodiment, the present disclosure relates to solution formulations containing an IL-31 antagonist as an active ingredient, the solution formulations further containing arginine and/or a salt thereof. In other non-limiting embodiments, the present disclosure relates to methods for stabilizing an antibody (for example, an anti-IL-31RA antibody) in an antibody-containing formulation, methods for suppressing antibody aggregation (aggregate formation) in an antibody-containing formulation, and methods for reducing components with charge heterogeneity in an antibody-containing formulation, the methods being characterized in that the formulation is prepared to contain arginine and/or a salt thereof, and/or sucrose and/or trehalose.
US11260120B2 Immunogenic composition comprising a fusion peptide derived from superantigen toxoids
The present disclosure provides immunogenic compositions useful in prevention and treatment of Staphylococcus aureus infection. In particular, the disclosure provides multivalent oligopeptides, fusion proteins comprising two or more staphylococcal superantigen (SAg) proteins, or any fragments, variants, or derivatives thereof fused together as a single polypeptide in any order.
US11260119B2 Escherichia coli compositions and methods thereof
In one aspect, the invention relates to an immunogenic composition comprising modified O-polysaccharide molecules derived from E. coli lipopolysaccharides and conjugates thereof. Multivalent vaccines may be prepared by combining two or more monovalent immunogenic compositions for different E. coli serotypes. In one embodiment, the modified O-polysaccharide molecules are produced by a recombinant bacterium that includes a wzz gene.
US11260117B2 Anti-CD47 x anti-mesothelin antibodies and methods of use thereof
The invention also relates to novel bispecific antibodies carrying a different specificity for each binding site of the immunoglobulin molecule, where one of the binding sites is specific for CD47 and the second is specific for mesothelin (MSLN).
US11260104B2 Carrier composition for eye drops and pharmaceutical composition including the same
The present disclosure provides a carrier composition for eye drops in which a substance to be delivered is loaded in a carrier, wherein the substance to be delivered includes one or more selected from the group consisting of an anti-inflammatory agent, a glaucoma treatment agent, a calcium channel blocker (CCB), an NMDA-receptor blocker, an antioxidant, a nitric oxide synthase inhibitor, a heat shock protein (HSP), a cystinosis treatment agent, and an antibiotic, the carrier has a spherical shape, the carrier includes a multilayer shell in a region ranging from the center to the surface of the carrier, the multilayer shell includes a core located in the center of the carrier and including a carboxymethyl cellulose (CMC)-based hydrogel having a degree of substitution (D.S.) of 0.9, a first shell located on the surface of the core and including a CMC-based hydrogel having a degree of substitution of 0.8, a second shell located on the surface of the first shell and including a CMC-based hydrogel having a degree of substitution of 0.6, and a third shell including a CMC-based hydrogel having a degree of substitution of 0.65, and the multilayer shell includes the core having a radius equal to 25% of the radial length of the carrier, the first shell having a thickness equal to 20% of the radial length, the second shell having a thickness equal to 40% of the radial length, and the third shell having a thickness equal to 15% of the radial length, and a pharmaceutical composition including the same.
US11260101B2 Repair peptide for use in promoting post-traumatic tissue repair and regeneration, and application thereof
Provided are a repair peptide for use in promoting post-traumatic tissue repair and regeneration, and an application thereof. The repair peptide is a linear or cyclic peptide which is 4-15 amino acids in length and which contains four or more consecutive GPANVET core sequences.
US11260099B2 Pet food compositions
Described herein are pet food compositions comprising a Camellia extract obtained from the tissue of a tea which is greater than about 40% oxidized; and a fiber component, wherein the Camellia extract and the fiber component are present in an amount effective to provide, after about 24 hours post-ingestion, a fecal hydrogen sulfide concentration of less than 450 mg/L, and a colonic lumen pH of less than 5.0. Methods of making and using these pet food compositions are also described.
US11260098B2 Method for suppressing obesity or development of obesity
An appetite-suppressing composition is characterized by comprising, as an active component, the liquid component derived from Indian mulberry (Morinda citrifolia). The solution is the liquid component extracted from fermented Indian mulberry fruits, which includes the residual liquid containing the >3,000 component and the filtrated liquid containing the <3,000 component. Considerably, provided is the food that possesses the appetite-suppressing composition without showing the non-specific effect on appetite suppression.
US11260095B2 Modification of plant lipids containing PUFAs
The present invention generally is concerned with the modification of plant lipids containing PUFAs. In this context, the invention is particularly concerned with plants and plant materials for such modifications, wherein the plants preferably are oilseed plants. Regarding plant parts, the invention is particularly concerned with seeds of such plants and preferably seeds of oilseed plants. The invention is also concerned with plant positions obtainable or obtained by the modification method of the invention, and with full stuff of feedstuff comprising such liquid compositions.
US11260090B2 Modified arenavirus
Provided are modified arenaviruses and populations thereof, wherein the modified arenaviruses include i) an introduced PPXY domain; ii) an increased number of PPXY domains; iii) a substituted amino acid in place of S41 in a viral Z protein that is not a substrate for a serine or tyrosine kinase, or a combination of i)-iii). A PPXY domain can include a phosphomimetic replacement of the Y amino acid. Modified Old World and New World arenaviruses are included. Arenavirus production is provided using cell cultures that contain a kinase inhibitor that inhibits a kinase that can phosphorylate the Y amino acid of the PPXY domain, or by cells that have disrupted kinase gene expression, or by cells that have a disrupted ESCRT system. Also provided are pharmaceutical formulations that contain modified arenaviruses, and methods of using such formulations for stimulating an immune response hat is fully or partially protective against arenavirus infection.
US11260089B2 Products of manufacture comprising bacteriophages
Provided are compositions and methods for treating, ameliorating and preventing various infections, disorders and conditions in mammals, including genetically-predisposed and chronic disorders, where a microbial or bacterial flora is at least one causative or symptom-producing factor, where exemplary compositions are products of manufacture, a food, a drink, a nutraceutical, a dietary supplement, a formulation, a pharmaceutical or a pharmaceutical preparation comprising at least one or several of a plurality of isolated, or substantially purified bacteriophages or prophages, or bacteriophage subunits, a milk, a milk product, milk lipid, milk fat globule (MFG) macromolecule, a milk mucin, a milk glycolipid, a milk free glycan, a milk mucin-like glycoprotein, a milk protein, a milk sugar or lactose, a milk fat or butterfat, a milk vitamin. In alternative embodiment, provided are compositions and methods for treating, preventing or ameliorating an infection, for example, an infection in the gastrointestinal tract, or bowel.
US11260083B2 Compositions and methods for treating and preventing graft versus host disease
Provided herein are compositions and methods for administering bacterial strains to reduce GvHD and improve survival after allogeneic BMT.
US11260077B2 Process for obtaining a sprinkling compound of microvascular endothelial skin cells and mesenchymal stem cells and method of application for tissue regeneration
The invention relates to a process for obtaining a cellular sprinkling compound and to the respective method of application to provide a therapeutic treatment for skin injuries, based on the implantation, by sprinkling and/or spraying, of human mesenchymal stem cells and microvascular endothelial cells that have been pre-expanded in vitro and resuspended in a regenerative solution for cellular implantation of biocompatible biomaterials. The solution is formed by blood plasma rich in growth factors obtained from the patient to be treated and, in some cases, by medical-grade type I collagen and by medical-grade hyaluronic acid, which potentiates the regeneration, re-epithelialization, and reconstruction of skin tissue.
US11260075B1 Non-thermal atmospheric plasma to treat hair loss
Non-thermal Atmospheric Plasma (NAP) from a plasma source is mixed with a liquid medium and the resulting compound is applied to the scalp to treat hair loss. The NAP-medium compound may be applied to the surface of the scalp, or produced in situ, or injected into the scalp.
US11260073B2 Compounds and methods for modulating C90RF72
Disclosed herein are compounds and methods for modulating C9orf72 transcript. Such compounds and methods are useful to treat, prevent, or ameliorate neurodegenerative diseases in an individual in need thereof.
US11260070B2 Methods of treating feline coronavirus infections
Provided are methods of treating feline Coronavirus infections using carbanucleoside compounds having a 1′-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl) substituent, or a pharmaceutically acceptable salt thereof. An exemplary compound is (2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile.
US11260069B2 Nicotinamide riboside and pterostilbene compositions and methods for treatment of neurodegenerative disorders
Compositions containing a combination of nicotinamide riboside and pterostilbene for treating neurodegenerative disorders, and methods of treating neurodegenerative disorders using these compositions and their equivalents are described. The neurodegenerative disorders that can be treated using these compositions or methods can include parkinson's disease, huntington's disease, alzheimer's disease, and the like. In an embodiment, the compositions containing a combination of nicotinamide riboside and pterostilbene can be prepared as oral formulations. In some embodiments, a dietary supplement comprises nicotinamide riboside and/or pterostilbene or equivalents.
US11260068B2 Long-circulating liposome modified with c(RGD-ACP-K)
The present invention relates to a long-circulating liposome modified with c(RGD-ACP-K). The present invention pertains to the field of pharmaceutical preparations, in particular to the field of targeted pharmaceutical preparations. More specifically, the present invention relates to a long-circulating liposome, the surface of the liposome being modified with c(RGD-ACP-K), and the liposome comprising doxorubicin or a pharmaceutically acceptable salt thereof such as doxorubicin hydrochloride as an anti-cancer active agent. The long-circulating liposome can targetedly deliver the anti-cancer active agent into tumor neovascular endothelial cells and tumor cells and can prolong the circulation time of the liposome in vivo, thereby enhancing the therapeutic effect of anti-tumor medicaments.
US11260061B2 Corticosteroid containing orally disintegrating tablet compositions for eosinophilic esophagitis
The present invention is directed to orally administered compositions of topically acting corticosteroids for the treatment of inflammation of the gastrointestinal tracts such as eosinophilic esophagitis. The present invention also provides a method for treating conditions associated with inflammation of the gastrointestinal tract in an individual. The method comprises administering to an individual in need thereof a pharmaceutical composition of the present invention as orally disintegrating tablets comprising a topically active corticosteroid adsorbed onto a pharmaceutically acceptable carrier such as silicified microcrystalline cellulose.
US11260058B2 Compositions and method of treating cancer
The disclosure provides for compounds of the general structure: and methods of using and compositions comprising the compounds for treating infections, cancer and neoplastic diseases and disorders.
US11260055B2 Oral pharmaceutical composition of lurasidone and preparation thereof
The present invention relates to an oral pharmaceutical composition, particularly a tablet, comprising an active ingredient lurasidone or its pharmaceutically acceptable salt(s) or solvate(s) thereof and one or more pharmaceutical excipient(s); and a process for its preparation.
US11260048B2 Compounds and compositions for inhibiting retinal pigment epithelium degeneration and methods using the same
There are provided inter alia compounds capable of inhibiting retinal pigment epithelium (RPE) degeneration or geography atrophy (GA) associated with age-related macular degeneration (AMD), and methods of using the same.
US11260047B2 Formulations of AG10
The present disclosure provides high-load tablet formulations of AG10 or a pharmaceutically acceptable salt thereof. In some aspects, provided herein are table formulations of AG10 or a pharmaceutically acceptable salt thereof that include at least 40% or more AG10 by weight and at least one pharmaceutical excipient selected from one or more fillers, one or more binders, one or more disintegrants, and one or more lubricants.
US11260045B2 Method of maximizing epigallocatechin gallate content in tea
This invention describes a new method to maximize the epigallocatechin gallate (EGCG) content of brewed tea made using leaves and buds from C. sinensis. Unlike conventional tea processing methods, the method of the invention aims to minimize the leaf withering step, the oxidation step and any heating steps, all of which are present in many conventional tea processing methods. The method of the invention treats minimally withered tea leaf and bud material with an acid treatment and then a maceration treatment, optionally freezing the acid-treated material for storage purposes. The brewed tea resulting from the acid-treated and macerated leaves has a significantly higher EGCG content than conventionally produced teas.
US11260044B2 TRPV1 activation-modulating complex mixtures of cannabinoids and/or terpenes
Described are methods of modulating the activation of the TRPV1 ion channel by administering at least one cannabinoid and/or terpene compound.
US11260042B2 Pharmaceutical combination for the treatment of cancer
A pharmaceutical combination comprising (A): a polyunsaturated fatty acid and (B): a chemotherapeutic agent compound for the simultaneous, separate or sequential use in the treatment of a cancer in a human patient.
US11260033B2 Compositions for the delivery of therapeutic agents and methods of use and making thereof
Some embodiments pertain to nanoparticle-based compositions and their use in methods for the delivery of CBD to subjects. In some embodiments, the compositions are stable for prolonged periods of time and provide enhanced bioavailability.
US11260032B2 Method for preparing biofilm-coated drug nanocrystal and application thereof
A nano drug delivery system includes a biofilm-coated drug nanocrystal. A drug in a physical form of nanocrystal is directly used as a rigid supporting skeleton, and is filled in a biofilm. The nano drug delivery system has the advantages of high drug loading capacity, good biocompatibility, long systemic circulation time and drug sustained release.
US11260031B2 Protein particle with a poorly water-soluble drug encapsulated therein and preparation method thereof
The present invention relates to a protein particle with a poorly water-soluble drug encapsulated therein and a preparation method therefor. The preparation method comprises the following steps: i) dissolving a poorly water-soluble drug and a liquid solubilizer into a good solvent; ii) partially or fully removing said good solvent from the product of step i); iii) mixing the product of step ii) with a protein; and iv) dispersing the product of step iii) in a poor solvent. The preparation method is simple and is suitable for industrial production.
US11260030B2 Oral tablet for delivery of active ingredients to the gastrointestinal tract
An oral tablet for delivery of active ingredients to the gastrointestinal tract includes a population of particles and an active ingredient to be delivered to the gastrointestinal tract. The population of particles includes directly compressible (DC) and non-directly compressible (non-DC) sugar alcohol particles, the non-DC particles providing the tablet with a plurality of discrete non-DC areas, and the non-DC areas resulting in induced saliva generation upon mastication of the tablet, wherein the tablet is designed to be masticated and designed to deliver the active ingredient to the gastrointestinal tract as part of the saliva generated upon mastication of the tablet.
US11260029B2 Fish feed compositions containing a neonicotinoid for preventing and treating parasite infections
The present disclosure relates to methods of preventing or treating parasite infection in a plurality of fish in need thereof, comprising administering to the fish an effective amount of a medicated fish feed. The medicated fish feed comprises fish feed granules or pellets coated with a composition comprising a neonicotinoid such as imidacloprid and a carrier having a high apparent digestibility coefficient such as a processed/cooked corn protein concentrate.
US11260025B1 In situ gelling composition as a pH-selective and mucoadhesive sustained release drug delivery system
An in situ gelling composition comprising nanoparticles comprising soy protein and a bioactive agent, and a sodium alginate film, wherein the nanoparticles are encapsulated in the film. The in situ gelling composition maybe incorporated into a solid dosage form or reconstituted with water for oral administration to a subject in need of sustained release of the bioactive agent.
US11260022B2 Method for producing oral composition, and oral composition
Provided are: a method for producing an oral composition suitable for treatment or prevention of a disease or symptom in the oral cavity; and an oral composition produced by the production method. The oral composition production method characterized by including a mixing step of mixing earthworm castings with water and a collecting step of collecting vaporized water generated from a mixture obtained in the mixing step to obtain a liquid; and the oral composition produced by the production method. It is preferred to further mix an organic substance together with the earthworm castings and the water in the mixing step.
US11260020B2 Topical compositions and methods for reducing oxidative stress
Compositions for reducing skin aging resulting from oxidative stress and/or photodamage are disclosed herein. The compositions can be topically applied to a skin region to reduce or prevent skin wrinkles, fine lines, thinning skin, sagging skin, skin dryness, and skin itchiness.
US11260019B2 Anhydrous cosmetic compositions comprising pearlescent pigment and a diester
Compositions disclosed include pearlescent pigment, talc, boron nitride, and a lipid portion. The lipid portion includes a polydialkylsiloxane, a silicone wax, and a diester of a dicarboxylic acid and a fatty alcohol. The composition is substantially free of water. The composition is generally in the form of a pressed-powder. Methods of use are also disclosed.
US11260018B2 Approaches for improving skin hydration and moisturization
The present disclosure generally relates to approaches for improving water absorption and retention by the skin's surface. In particular, the disclosure provides compositions and methods for preparing mixtures comprised of ethoxylated oils and water or mixtures comprised of micro or nano emulsions and water, which provide enhanced skin hydration or moisturization to a subject.
US11260014B2 Seaweed-derived cosmetic compositions
A cosmetic composition is disclosed for applying to skin. The composition includes a liquid and dispersed in the liquid: any amount or form of fucoidan, any amount or form of beta glucan; and any amount of a marine extract. When the cosmetic composition is applied to the skin, the appearance of the skin is improved.
US11260013B2 Compositions and methods for providing hair growth
Compositions and methods for topical treatment of hair loss in otherwise normal skin that is affected by alopecia are presented. Such compositions include defensins in concentrations that are below those that exhibit antimicrobial activity, and can be in the form of a topically applied gel, lotion, wash, shampoo, cream, or mask. Various formulations for such compositions, which can include various pharmaceutically acceptable stabilizers, emollients, and fragrances, are provided. Such compositions and methods can be used in conjunction with traditional methods for treatment of hair loss.
US11260012B2 Preserved silk protein fragment compositions and articles manufactured therefrom
In some embodiments, a composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals. In some embodiments, a composition is disclosed that includes silk fibroin-based protein fragments and is suitable for use in consumer applications. In some embodiments, a preserved composition is disclosed that includes silk fibroin-based protein fragments. In some embodiments, a method of preserving a solution using silk fibroin-based protein fragments is disclosed.