Document Document Title
US10106618B2 Anti-CD40L antibodies
Anti-human CD40L antibodies engineered to lack the ability to activate platelets and methods for treating patients having a CD40L-associated disease.
US10106616B2 Antagonist antibodies to human prolactin receptor (PRLR)
The present invention provides antibodies that bind to prolactin receptor (PRLR) and methods of using the same. According to certain embodiments, the antibodies of the invention bind human PRLR with high affinity. In certain embodiments, the invention includes antibodies that bind PRLR and block prolactin-mediated cell signaling. In other embodiments, the invention includes antibodies that bind PRLR but do not block prolactin-mediated cell signaling. The antibodies of the invention may be fully human antibodies. The invention includes anti-PRLR antibodies conjugated to a cytotoxic agent, radionuclide, or other moiety detrimental to cell growth or proliferation. The antibodies of the invention are useful for the treatment of various cancers as well as other PRLR-related disorders. The present invention also includes antibody drug conjugates comprising an antibody or antigen-binding fragment thereof that specifically binds a class I cytokine receptor, wherein the antibody or antigen-binding fragment thereof is conjugated to a cytotoxic agent.
US10106614B2 Insulin-like growth factor 1 receptor-specific antibodies and uses thereof
The blood-brain barrier (BBB) prevents transport of molecules larger than 500 Daltons from blood to brain. Receptor-mediated transcytosis (RMT) facilitates transport across the BBB of specific molecules that bind receptors on brain endothelial cells that form the BBB. An insulin-like growth factor 1 receptor (IGF1R)-binding antibody or fragment thereof is identified that transmigrates the BBB by RMT. The antibody or fragment is used to deliver a cargo molecule across the BBB, wherein the cargo molecule may be a therapeutic or detectable agent. The antibody is a camelid VHH, prepared by immunizing a llama with a 933-amino acid IGF1R polypeptide. Humanized forms of the camelid VHH are also generated.
US10106610B2 Antibodies comprising chimeric constant domains
Antibodies, antigen-binding proteins and Fc-fusion proteins that comprise recombinant polypeptides containing a chimeric heavy chain constant region sequence are provided that bind to certain Fc receptors however have reduced effector functions. Methods of making constructs for expression of such chimeric Fc-containing antibodies, antigen-binding proteins and Fc-fusion proteins in cell systems, and methods of producing and isolating the chimeric Fc-containing proteins are provided.
US10106609B2 CD7 nanobodies, encoding sequence and use thereof
Provided is a nanometer antibody for human CD7 molecule and an encoding DNA sequence thereof. The nanometer antibody can be efficiently expressed in Escherichia coli, and can be used for preparing an agent for the detection of CD7 molecule and targeted therapy.
US10106606B2 Targeting tissue factor to activated platelets
The current invention relates to procoagulant fusion proteins, polynucleotides that encode said fusion proteins and cells that expresses said fusion proteins. Furthermore, the current invention relates to fusion proteins for use as a medicament. Individuals that have a coagulopathy, such as haemophilia A and B with or without inhibitors, may be treated with fusions proteins of the current invention.
US10106605B2 Compositions and methods for antibodies targeting Epo
The present invention relates to compositions and methods for the inhibition of EPO. The invention provides antibodies and antigen binding fragments thereof that bind to EPO and are able to inhibit EPO-dependent cell proliferation and/or EPO-dependent cell signaling.
US10106604B2 Method of treating auto-inflammatory syndromes with IL-1beta antibodies related to canakinumab
This invention relates to a novel use of IL-1β-ligand/IL-1 receptor disrupting compounds (herein referred to as “IL-1 beta Compounds”); such as small molecular compounds disrupting IL-1b ligand-IL-1 receptor interaction, IL-1b antibodies or IL-1 receptor antibodies, e.g. IL-1b binding molecules described herein, e.g. antibodies disclosed herein, e.g. IL-1b binding compounds or IL-1 receptor binding compounds, and/or RNA compounds decreasing either IL-1b ligands or IL-1 receptor protein levels, in the treatment and/or prevention of auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome and to methods of treating and/or preventing auto-inflammatory syndromes, e.g. Juvenile rheumatoid arthritis or adult rheumatoid arthritis syndrome, in mammals, particularly humans.
US10106600B2 Bispecific antibodies
The present invention relates to bispecific antibodies, methods for their production, pharmaceutical compositions containing said antibodies, and uses thereof.
US10106599B2 Antibody and antibody-containing composition
For many diseases due to microbes or the like, proliferation of microbes themselves is a cause of a symptom. However, there were cases where a substance released by the microbes is a cause of a symptom. In such cases, when attempting to treat a disease with an antibody, it was necessary to obtain an antibody against an antigen that is a substance causing the disease. However, it was difficult to find the underlying substance causing the disease among substances released by the microbes. An antibody (polyclonal) binding to not only an antigen but also to a substance, which is secreted by the antigen and accelerates the deterioration of a symptom, is obtained by immunizing birds with a lysis solution produced from lysing microbial cells as an antigen. Further, an antibody obtained with a surface protein of a virus as an antigen is expected to inhibit an infection by a virus.
US10106596B2 Fibrous protein processing method
Disclosed is a process for preparing proteinaceous materials. The process comprises solubilizing fibrous protein by contacting it with an alkaline solution, ageing the resulting mixture to form a homogenous solution, and coagulating the resulting solution to form the proteinaceous material. The proteinaceous materials may be produced as, for example, fibers, films, sheets, coatings, particles, shapes, foams or composites.
US10106593B2 Peptides and combination of peptides for use in immunotherapy against various tumors
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10106592B2 Interleukin-4 receptor-binding fusion proteins and uses thereof
The present invention relates to interleukin-4 receptor-binding fusion proteins. More specifically, the invention provides, in part, fusion proteins that include an interleukin-4 or interleukin-13 protein moiety joined to an anti-apoptotic Bcl-2 family member protein moiety.
US10106591B2 BMP peptides and methods of use
The invention relates to truncated growth factors and variants thereof. The invention also relates to methods of making and using the truncated growth factors. The invention further relates to compositions including a protease and a growth factor comprising a bone morphogenic protein (BMP) or a variant thereof. The invention also relates to methods of using the composition.
US10106590B2 BH4 stabilized peptides and uses thereof
Provided herein are polypeptides containing stabilized BH4 domains of BCL-2 family proteins that are capable of binding and/or inactivating and/or modulating BAX protein, and/or its close homologs BAK and BOK, and/or other physiological BH4 targets. Also provided are compositions containing these polypeptides and methods of treating cytotoxic diseases that include administering to a subject one of the polypeptides.
US10106588B2 Nucleic acids encoding peptides for treating wounds, anti-angiogenic compounds and uses thereof
The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like.
US10106586B2 Sequence-determined DNA fragments encoding peptide transport proteins
The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3′ termination sequence, and are also useful in controlling the behavior of a gene in the chromosome, in controlling the expression of a gene or as tools for genetic mapping, recognizing or isolating identical or related DNA fragments, or identification of a particular individual organism, or for clustering of a group of organisms with a common trait.
US10106585B2 Compositions and methods for suppression of inhibitor formation against coagulation factors in hemophilia patients
Protein replacement therapy for patients with hemophilia or other inherited protein deficiencies is often complicated by pathogenic antibody responses, including antibodies that neutralize the therapeutic protein or that predispose to potentially life-threatening anaphylactic reactions by formation of IgE. Using murine and canine hemophilia as a model, we have developed a prophylactic protocol against such responses that is non-invasive and does not include immune suppression or genetic manipulation of the patient's cells. Oral delivery of a coagulation factor expressed in chloroplasts, bioencapsulated in plant cells, effectively blocked formation of inhibitory antibodies in protein replacement therapy. Inhibitor titers were mostly undetectable and up to 100-fold lower in treated subjects when compared to controls. Moreover, this treatment eliminated fatal anaphylactic reactions that occurred after four to six exposures to intravenous coagulation factor protein. Finally, the method can effectively be used to reverse or reduce undesirable pre-existing inhibitor titers.
US10106582B2 Complex-formation-modulating agents and uses therefor
Disclosed are methods and agents for modulating proliferation, migration and/or survival of cells. More particularly, the present invention discloses molecules that have any one or more activities selected from: inhibiting binding of vitronectin to at least one vitronectin-binding partner selected from an IGF and IGFBP, inhibiting formation of a complex comprising vitronectin and at least one vitronectin-binding partner selected from an IGF and IGFBP, or inhibiting proliferation or survival of a hyperproliferative cell (e.g., a neoplastic cell or non-neoplastic cell), or inhibiting migration or invasion of a hyperproliferative cell (e.g., a neoplastic cell or a non-neoplastic cell). Additionally, the present invention discloses the use of these molecules in methods and compositions for treating or preventing hyperproliferative cell disorders including neoplastic (e.g., cancers such as epithelial cancers) and non-neoplastic disorders.
US10106577B2 Agonists of neurotrophin receptors and their use as medicaments
The invention relates to compounds of Formula I: and pharmaceutically acceptable salts and prodrugs thereof, wherein R1, R2, and R3 are defined as set forth in the specification. The compounds are agonists of neurotrophin (such as nerve growth factor) receptors.
US10106573B2 Fluorescent dyes and methods of use thereof
Provided are methods for labeling target molecules, such as nucleic acids, with fluorescent dye compounds having the formula One method embodiment includes contacting reactive group Z of the fluorescent dye compound with the target molecule such that reactive group Z reacts with the target molecule to form a covalent bond between the group and the target molecule. Another method embodiment includes contacting a fluorescent dye compound that further includes a first member of a binding pair, with a target molecule that includes a second member of the binding pair. Also provided are target molecules labeled with the fluorescent dye compounds.
US10106571B2 HCV polymerase inhibitors
The invention provides compounds of the formula: wherein B is a nucleobase selected from the groups (a) to (d): and the other variables are as defined in the claims, which are of use in the treatment or prophylaxis of hepatitis C virus infection, and related aspects.
US10106570B2 Edible plasticizers for food and food packaging films
Disclosed are plasticizers, salts thereof, chelates thereof and cleavage derivatives thereof, that exhibit a superior combination of properties. The plasticizers can be used for a variety of purposes, including food preparation, cosmetics, beverages and polymeric matrices. The plasticizers can be prepared by esterifying gallic acid, fulvic acid, or tannic acid.
US10106557B2 Preparation method for benzoxazoleoxazine ketone compound and intermediate and crystal form thereof
A preparation method for a high-purity benzoxazoleoxazine ketone compound, a crystal form thereof, and an intermediate compound for preparing a compound of formula (I), and a preparation method therefor.
US10106556B2 Heterocyclic compound
The present invention provides a compound having an MAGL inhibitory action, which is expected to be useful as an agent for the prophylaxis or treatment of neurodegenerative diseases (e.g., Alzheimer's disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, traumatic brain injury, glaucoma, multiple sclerosis etc.), anxiety disorder, pains (e.g., inflammatory pain, cancerous pain, neurogenic pain etc.), epilepsy, depression and the like.The present invention relates a compound represented by the formula (I): wherein each symbol is as described in the specification, or a salt thereof.
US10106555B2 Max binders as MYC modulators and uses thereof
The present disclosure provides compounds of Formula (I′), Formula (I), Formula (II), Formula (II-A), Formula (III), and Formula (IV). The compounds described herein are MAX binders and/or modulators of Myc, Mad, or Mxi1 (e.g., inhibitors of Myc, Mad, or Mxi1), and may be useful in treating a subject with a disease associated with Myc, such as proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions and kits including the compounds described herein, as well as methods of using and uses of the compounds, compositions, and kits.
US10106546B2 Immunoregulatory agents
Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
US10106545B2 Pyrazolopyrimidine compounds
The present teachings provide a compound represented by structural formula (I-0), or a pharmaceutically acceptable salt thereof. Also described are pharmaceutical compositions and methods of use thereof.
US10106544B2 1,2-dihydro-3H-pyrrolo[1,2-C]imidazol-3-one derivatives and their use as antibacterial agents
The invention relates to antibacterial compounds of formula I wherein R1 is one of the groups represented below wherein A is a bond, CH═CH or C≡C; U is N or CH; V is N or CH; W represents N or CH; and R1A, R2A, R3A, R1B and R1C are as defined in the claims; and salts thereof.
US10106543B2 Antimicrobial compounds and methods of making and using the same
The present invention relates generally to the field of antimicrobial compounds and to methods of making and using them. These compounds are useful for treating, preventing, reducing the risk of, and delaying the onset of microbial infections in humans and animals.
US10106542B2 Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives of formula (I) as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 (“mGluR2”) useful for the treatment of central nervous system disorders in which the mGluR2 subtype of metabotropic receptors is involved (e.g. mood disorder, schizophrenia, etc.). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for treatment of central nervous system disorders in which the mGluR2 subtype of metabotropic receptors is involved.
US10106541B2 Intermediates for preparing CGRP receptor antagonists
The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine.
US10106538B2 Inhibitors of protein kinases
Protein kinases are regulators of cellular signaling and their functional dysregulation is common in carcinogenesis and many other disease states or disorders. The present invention relates to novel chemical entities that have biological activity to modulate mammalian protein kinase enzymes. In particular, compounds of the invention display potent inhibition of breast tumor related kinase (BRK).
US10106524B2 2,3,4,5-tetrahydropyridin-6-amine and 3,4-dihydro-2H-pyrrol-5-amine compound inhibitors of beta-secretase
The present invention relates to 2,3,4,5-tetrahydropyridin-6-amine and 3,4-dihydro-2H-pyrrol-5-amine compound inhibitors of beta-secretase having the structure shown in Formula (I) wherein the radicals are as defined in the specification. The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention and treatment of disorders in which beta-secretase is involved, such as Alzheimer's disease (AD), mild cognitive impairment, senility, dementia, dementia with Lewy bodies, Down's syndrome, dementia associated with stroke, dementia associated with Parkinson's disease, dementia associated with beta-amyloid, age-related macular degeneration, type 2 diabetes or metabolic disorders.
US10106517B2 Method for producing tetrahydropyranyl esters
The present invention relates to a method for preparing tetrahydropyranyl esters from the corresponding 4-hydroxytetrahydropyran compounds by reaction with a ketene compound.
US10106512B2 Metal plating compositions
Reaction products of primary and secondary diamines and bisanhydrides are included as additives in metal electroplating baths. The metal electroplating baths have good throwing power and deposit metal layers having substantially planar surfaces. The metal plating baths may be used to deposit metal on substrates with surface features such as through-holes and vias.
US10106509B2 Method for producing kakeromycin and derivatives thereof
Provided is a production method of kakeromycin and a derivative thereof showing an antifungal activity and cytotoxicity and expected as a new antifungal agent or anticancer agent, by chemical synthesis. A production method of a compound represented by the formula (1): wherein R is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group; and n is 0 or 1, or a salt thereof, including a step of subjecting a compound represented by the formula (2): wherein R and n are as defined above, or a salt thereof, to an oxidation reaction.
US10106508B2 Quinazoline heterocyclic compound as EGFR kinase inhibitor and preparation and application thereof
The present invention relates to an N-substituted-phenyl-5-substituted-alkoxy-2,3-dihydro-[1,4]dioxane[2,3-f]quinazolin-10-amine (I) or 4-substituted-arylamino-6-substituted-alkyl-6H-[1,4]oxazino[3,2-g]quinazoline-7(8H)-one (II) type compounds, a preparation method thereof and an application thereof as an inhibitor for epidermal growth factor receptor (EGFR) (comprising some mutant forms of EGFR) to treat cancer. These compounds and salts thereof can be used to treat or prevent various cancer diseases.
US10106505B2 Composition and methods for modulating a kinase cascade
The invention relates to compounds and methods for modulating one or more components of a kinase cascade. The invention also relates to substantially pure compound 1 and substantially pure compound 1 salt (e.g., compound 1 hydrochloride salt and compound 1 benzenesulfonate salt). The invention further relates to methods of preparing substantially pure compound 1 and compound 1 salts.
US10106502B2 Direct inhibitors of Keap1-Nrf2 interaction as antioxidant inflammation modulators
A method of identifying compounds as direct inhibitors of Keap1-Nrf2 interaction through high-throughput screening and lead development. The direct inhibitors of Keap1-Nrf2 interaction are more specific and free of various undesirable effects than existing indirect inhibitors, and are potential drug candidates of chemopreventive and therapeutic agents for treatment of various diseases or conditions involving oxidative stress and/or inflammation, including but not limited to cancers, diabetes, Alzheimer's, and Parkinson's. Novel compounds are identified and methods of preventing or treating diseases or conditions related to Keap1-Nrf2 interaction activity by use of the novel compounds identified or compositions containing such compounds are also disclosed.
US10106490B2 Lipids and lipid nanoparticle formulations for delivery of nucleic acids
Compounds are provided having the following structure: or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein R1a, R1b, R2a, R2b, R3a, R3b, R4a, R4b, R5, R6, R7, R8, R9, L1, L2, a, b, c, d and e are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.
US10106487B2 Oxidative dehydrogenation of lactate esters to pyruvate esters
The present invention relates to a simple one step oxidative dehydrogenation process for the synthesis of alkyl pyruvate with 100% selectivity towards alkyl pyruvate comprising reacting an alkyl lactate in the presence of catalyst at the temperature ranging from 25-100° C. for the time period ranging from 5 to 40 hours in an organic solvent and hydrogen peroxide to afford alkyl pyruvate.
US10106486B2 Method for producing carboxylic acid esters and the use thereof as plasticizers
The present invention relates to a process for the production of carboxylic esters by reaction of carboxylic acids and/or carboxylic anhydrides with at least one alcohol selected from alkanols having at least 5 carbon atoms, cycloalkanols, and alkoxy-alkanols, in the presence of an acidic esterification catalyst. The invention further relates to the use of the resultant carboxylic esters as plasticizers or in a plasticizer composition for thermoplastic polymers and elastomers.
US10106483B2 Process for preparation of azelaic acid
Provided is a process for preparing azelaic acid.
US10106480B2 Methods for producing fuels, gasoline additives, and lubricants using amine catalysts
Provided herein are methods for producing ketone(s) from the condensation of methyl ketone(s) and alcohol(s) in the presence of an amine catalyst and a metal catalyst. Such amine catalysts may be supported, for example, on a silica-alumina support. Such ketones may be suitable for use in producing fuels, gasoline additives, and/or lubricants, or precursors thereof. The methyl ketone(s) and/or alcohol(s) may be obtained from renewable sources, such as by fermentation of biomass.
US10106476B1 Energy efficient methods for isomerization of a C5-C7 fraction with dividing wall fractional distillation
This invention relates to a method of separating an isomerization zone effluent mixture comprising between 5 and 8 carbon atoms into high octane isomerate product streams and low octane streams which may be recycled to the isomerization zone. The separation process makes use of a dividing wall column to efficiently perform the separation of high octane multibranched paraffins from low octane straight chain and single branched paraffins.
US10106475B1 High density turbine and diesel fuels from tricyclic sesquiterpenes
A method for converting cedarwood oil into high density fuels including, hydrogenating cedarwood oil in the presence of at least one hydrogenation catalyst to generate hydrogenated cedarwood oil, removing the hydrogenation catalyst from the hydrogenated cedarwood oil, purifying the hydrogenated cedarwood oil to produce a first high density fuel, isomerizing the first high density fuel in the presence of at least one acid catalyst to generate a hydrocarbon mixture including adamantanes, and distilling the adamantane mixture to produce a second alkyl-adamantane high density fuel.
US10106472B2 Compositions for controlling plant parasitic nematodes and methods for using same
Aspects of the invention include compositions for controlling plant parasitic nematodes. Compositions according to certain embodiments include a carbon skeleton energy compound, a chelating agent, macronutrients, micronutrients, an ionophore, exotic micronutrients and a plant parasitic nematode antagonist. Methods for using the compositions of the invention to control plant parasitic nematodes and kits having one or more compositions for controlling plant parasitic nematodes are also described.
US10106471B2 Biochars and biochar treatment processes
Treated biochar and methods for treating biochar are provided. The method for treating the biochar includes forcing, assisting or accelerating the movement of an infiltrant into the pores of the biochar, whereby the treatment affects properties of the biochar that provide for a more reliable and predictable biochar for use in various applications, including, but not limited to, agricultural applications.
US10106470B2 Method for incorporating micronutrients in the outer shell of urea-based particles
The invention concerns a method for incorporating micronutrients in an outer shell of urea-based particles, characterized in that it comprises the steps of a) applying a liquid concentrated mineral acid with a water content of at most 25 weight % to urea-based particles having a water content of at most 2 weight %, in order to at least form a double salt layer at the outer surface of the urea-based particles such that an acidified particle grasping layer is obtained, and subsequently b) applying a solid mineral base in powder form to the urea-based particles of step a) in order to react with the grasping layer of the urea-based particles; wherein the mineral acid or the solid mineral base are the source of any one of the micronutrients and wherein the liquid concentrated mineral acid and the solid mineral base in powder form are applied in a non-equimolar ratio between 0.1 and 1 mol/mol mineral acid/mineral base. The invention furthermore concerns a particulate urea-based fertilizer, comprising urea-based particles with a water content of at most 2 weight %, comprising micronutrients in an outer shell, the urea-based particles being obtained by a method according to the invention.
US10106468B2 Soilless media composition
An improved soilless media composition including (a) green tuff; and (b) a substrate such as peat or bark. A method of enhancing the growth of plants including adding plant propagative material to a soilless media composition comprising (a) green tuff; and (b) a substrate.
US10106465B2 Ceramic and preparation method therefor
A ceramic and a preparation method therefor are provided. The ceramic includes a zirconia matrix, and an additive dispersed inside and on an outer surface of the zirconia matrix. The additive is an oxide including elements A and B, where A is selected from at least one of Ca, Sr, Ba, Y, and La, and B is selected from at least one of Cr, Mn, Fe, Co, and Ni.
US10106459B2 Process and device for cement clinker production
In a process for the production of cement clinker, in which raw meal is preheated in a preheater (3) using the hot exhaust gases from a clinker kiln, and the preheated raw meal, which is optionally calcined in a calciner (4), is burned to clinker in the clinker kiln (2), wherein the preheater (3) comprises at least one string of a plurality of cyclone suspension-type heat exchangers (8, 9, 10), through which the kiln exhaust gas successively flows and in which the raw meal is preheated in stages, a partial stream of the kiln exhaust gas is diverted such that only a remaining residual stream of the kiln exhaust gas is utilized for preheating the raw meal.
US10106458B2 Vehicle window glass and method for producing same
Provided is a method for producing a vehicle window glass, the method being adapted to prevent peeling-off of a functional thin film from a ceramic shielding layer without masking the ceramic shielding layer with a masking tape. This production method includes: an application step of feeding a coating liquid for forming the functional thin film onto a principal surface of a glass sheet on which the ceramic shielding layer has been formed beforehand, so as to allow the coating liquid to flow in a predetermined direction on the principal surface; and a drying step of drying the fed coating liquid. In the application step, the glass sheet is set in such a position that the predetermined direction coincides with a first direction in which the maximum length of the principal surface is 30 cm or less (rather than with a second direction in which the maximum length is more than 50 cm) and thus that the distance the coating liquid flows on the principal surface is limited to 30 cm or less.
US10106454B2 Optical glass having negative anomalous partial dispersion / special short flint glasses
The present invention relates to optical glasses, in particular special short flint glasses (KZFS) and optical elements and components, which comprise these glasses, and use thereof and a method for producing such optical glasses. The optical glasses of the present invention are characterized by a pronounced short flint character and additionally by an excellent transmission and chemical resistance and workability. At that, the glasses of the invention can stand out due to lower costs of production caused by lower costs of raw materials and lower processing costs, due to their crystallization properties that can be handled also in smaller melting aggregates, and due to good environmental compatibility.
US10106452B2 System and method of continuous glass filament manufacture
A system and a method of manufacturing continuous glass filament fiberglass media comprises melting glass within a temperature controlled melter. Molten glass exits through a bushing plate with orifices of varying row configurations and orientations. The resulting fiberglass filaments are received on a rotating drum and sprayed with resin and aqueous solution. The resulting fiberglass mat is placed onto a let-off table then sprayed with aqueous solution before further processing.
US10106451B2 Glass rod machining method and machining apparatus
To prevent constriction machining from reducing usage efficiency of a glass rod, provided is a glass rod machining method including softening of softening a portion of the glass rod by heating the portion of the glass rod, and constricting of forming a constricted shape in the glass rod by moving one end of the glass rod relative to the other end of the glass rod at a constriction speed satisfying a condition that a constriction load acting as a tensile force on the glass rod does not extend beyond a predetermined range. In this method, the constricting includes, when constriction speed increases, making an adjustment to decrease a heating temperature of the glass rod. This method may include determining of determining the heating temperature of the glass rod during the constricting by referencing a heating temperature table in which heating temperatures corresponding to the constriction speed are stored in advance.
US10106447B2 Process to recover ammonium bicarbonate from wastewater
The present invention is a process, a method, and system for recovery and concentration of dissolved ammonium bicarbonate from a wastewater containing ammonia (NH3) using gas separation, condensation, filtration, and crystallization, each at controlled operating temperatures. The present invention includes 1) removal of ammonia from waste (sludges, semi-solids, and solids and liquids) without the use of chemicals at a temperature of at least 80 degrees Celsius, 2) mixing of the gaseous ammonia with carbon dioxide and water vapor and concentrating dissolved ammonium carbonate and ammonium bicarbonate using reverse osmosis at a temperature of between about 35 and 50 degrees Celsius, and 3) crystallizing concentrated dissolved ammonium carbonate and ammonium bicarbonate at a temperature of less than about 35 degrees Celsius to form solid ammonium bicarbonate and ammonium carbonate.
US10106444B2 Vitality stick system and method
A device for affecting water. The device for affecting water includes a first-end, a second-end, a length from the first end to the second-end and an extruded member. Gemstones, which generate a pleasant subliminal functional aesthetic, and visible messages, which may have positive neurological and meta-physical effects, are included. The device for affecting water is useful for providing trace mineral elements to humans and animals and for producing positive changes to the overall physical health and emotional well-being of a user.
US10106443B2 Composition for treating suspensions of solid particles in water and method using said composition
A composition for treating an aqueous suspension of mineral particles includes at least one water soluble polymer and at least one calcium salt, magnesium salt or both a Calcium salt and a Magnesium salt. The composition is in powder form.
US10106436B2 Selective adsorbent fabric for water purification
A water purification chamber is provided. In one embodiment, a system comprises a purification chamber comprising a selective adsorbent activated carbon fiber fabric including one or more selective functional groups that bind arsenic.
US10106433B2 Metal oxide nanoparticle material
A zirconia nanoparticle material includes a zirconia nanoparticle and a carbonate coordinated on a surface of the zirconia nanoparticle. The carbonate is 1 to 10 parts by weight of the zirconia nanoparticle.
US10106430B2 Oxycombustion systems and methods with thermally integrated ammonia synthesis
Oxycombustion systems and oxycombustion methods include thermally integrated ammonia synthesis. The oxycombustion systems may include an air separation unit that separates air into an oxygen stream and a nitrogen stream. An ammonia synthesis unit synthesizes ammonia from a hydrogen feed and the nitrogen stream to form a crude ammonia stream. An ammonia separation unit condenses the crude ammonia stream and separates the ammonia from any unreacted nitrogen and hydrogen to form a purified ammonia stream. An oxycombustion reactor combusts a fuel from a fuel feed stream in the presence of the oxygen stream from the air separation unit to generate hot water or steam. At least one thermal integration may be present in the oxycombustion systems and may be chosen from a reactor thermal linkage of the ammonia synthesis unit with the oxycombustion reactor, a separator thermal linkage of the air separation unit with the ammonia separation unit, or both.
US10106429B2 Method of making zeolites with hierarchical porosity
The present invention concerns zeolites with hierarchical porosity having a molar ratio Si/Al of between 1 and 1.4, inclusive, of which the average diameter, as a number, is between 0.1 μm and 20 μm, having controlled and optimized crystallinity, and having mesoporosity such that the mesoporous outer surface area is between 40 m2·g−1 and 400 m2·g−1. The present invention also concerns the method for preparing said zeolites with hierarchical porosity.
US10106428B2 Method for producing surface-modified silica nanoparticles, and surface-modified silica nanoparticles
[Problem]To provide a dispersion containing surface-modified silica nanoparticles highly dispersed in an organic dispersion medium and also having high transparency and storage stability.[Solution]Disclosed is a method for producing surface-modified silica nanoparticles comprising: preparing a first silica nanoparticle dispersion containing silica nanoparticles and an aqueous dispersion medium; replacing the aqueous dispersion medium in the first silica nanoparticle dispersion with an organic dispersion medium comprising at least one selected from cyclic esters or cyclic amides, to obtain a second silica nanoparticle dispersion; and mixing the second silica nanoparticle dispersion with a silane coupling agent represented by the formula (1): (each R1 is independently a hydrocarbon group of C1 to C20 and R2 is a hydrocarbon group of C1 to C3), to modify the surface of the silica nanoparticles.
US10106423B2 Method for preparing ultrahigh-purity silicon carbide powder
The present invention relates to a method for preparing an ultrahigh-purity silicon carbide powder, more particularly to a method for preparing an ultrahigh-purity silicon carbide granular powder by preparing a gel wherein a silicon compound and a carbon compound are uniformly dispersed via a sol-gel process using a liquid state silicon compound and a solid or liquid state carbon compound of varying purities as raw materials, preparing a silicon dioxide-carbon (SiO2—C) composite by pyrolyzing the prepared gel, preparing a silicon carbide-silicon dioxide-carbon (SiC—SiO2—C) composite powder via two-step carbothermal reduction of the prepared silicon dioxide-carbon composite, adding a silicon metal and then conducting carbonization and carbothermal reduction at the same time by heat treating, thereby growing the synthesized silicon carbide particle with an increased yield of the silicon carbide.
US10106419B2 Method of making graphene nanocomposites by multiphase fluid dynamic dispersion
A method of dispersing graphene and graphitic nanomaterials uses a multiphase fluid dynamic technique. The method includes a device, incorporating a high intensity fluid dynamics technique, controlling the expansion and compression ratio of the working stream that leads to an effective dispersion of the nanomaterial in the matrix. The condensation of the injected steam creates high intensity and controllable cavitation, leading to effective dispersion of the graphitic nanomaterial. The dispersion is most preferably done in a medium that creates a repulsive potential to balance the attractive inter-graphitic layer potential.
US10106418B2 Graphene aerogels
Graphene aerogels with high conductivity and surface areas including a method for making a graphene aerogel, including the following steps: (1) preparing a reaction mixture comprising a graphene oxide suspension and at least one catalyst; (2) curing the reaction mixture to produce a wet gel; (3) drying the wet gel to produce a dry gel; and (4) pyrolyzing the dry gel to produce a graphene aerogel. Applications include electrical energy storage including batteries and supercapacitors.
US10106416B2 Methods for treating an offgas containing carbon oxides
A method of treating an offgas includes purifying the offgas to remove particulate matter, water, undesirable gaseous components and inert gases to produce a dried carbon oxide gas feedstock, and converting at least a portion of carbon oxides in the dried carbon oxide gas feedstock into solid carbon. In other embodiments, a method includes passing a dried carbon oxide gas feedstock through a multi-stage catalytic converter. A first stage is configured to catalyze methane-reforming reactions to convert methane into carbon dioxide, carbon monoxide and hydrogen with residual methane. A second stage is configured to catalyze the Bosch reaction and convert carbon oxides and hydrogen to solid carbon and water.
US10106414B2 Molten iron-assisted method for producing aluminum nitride and device thereof
A molten iron-assisted method for producing aluminum nitride (AlN) and a device thereof are disclosed. Pure aluminum is introduced into a vacuumed molten iron bath continuously for producing a molten iron bath having the aluminum, then nitrogen is introduced into the molten iron bath having the aluminum. Production of AIN is controlled by having the concentration of aluminum in the molten iron bath having the aluminum controlled. At the time AIN is formed continuously in the molten iron bath having the aluminum, AIN floats to the surface of the molten iron bath having the aluminum. Ar and N2 may be blown and dust is removed by static electrons thereafter, such that pure aluminum nitride powder can be collected. Finally, the used gas is recycled and reused.
US10106406B2 Chemical reactor with manifold for management of a flow of gaseous reaction medium thereto
A chemical reactor (e.g. reformer reactor) system includes a manifold (126) for management of a flow of gaseous reaction medium thereto. Manifold (126) includes manifold housing (128) defining manifold chamber (129) and having at least one additional component selected from: a gas distributor (127); a heater; and a cavity having a seal within or adjacent to it.
US10106398B2 Micromechanical structure comprising carbon material and method for fabricating the same
A micromechanical structure comprises a substrate and a functional structure arranged at the substrate. The functional structure comprises a functional region which is deflectable with respect to the substrate responsive to a force acting on the functional region. The functional structure comprises a carbon layer arrangement, wherein a basis material of the carbon layer arrangement is a carbon material.
US10106394B2 Method of regulating pressure in pressurized beverage dispenser
A beverage dispenser with a variable pressure regulator cap assembly that includes a high pressure cavity defined by a cap body. The high pressure cavity receives pressurized gas from a compressed gas reservoir. A low pressure cavity is connected to the high pressure cavity via a high pressure gas passageway. The low pressure cavity defines a low pressure gas passageway that penetrates the cap body. A piston seat is positioned on a high pressure cavity side of the high pressure gas passageway. A piston regulates introduction of the pressurized gas into the high pressure gas passageway. A diaphragm is positioned between an ambient pressure cavity and the low pressure cavity and translates the piston relative to the piston seat. A main spring is positioned between a diaphragm and a spring hat. Rotation of the drive screw translates the spring hat to affect compression of the main spring against the diaphragm.
US10106390B2 Labeling machine
A machine for labeling containers includes a rotating carousel with a lower base which supports a plurality of supporting pans for the containers and an upper supporting structure for a plurality of heads which are intended to engage the top portion of the containers. The labeling machine further includes a device for feeding the containers to be labeled to the rotating carousel and a device for unloading the labeled containers. The feeding device includes at least one first device for conveying the containers to be labeled which is provided with first elements for supporting the containers to be labeled at the neck. The labeling machine includes first elements for varying the height of the bottom of the containers to be labeled in order to bring the bottom to substantially the same height as the supporting pans.
US10106389B2 Apparatus for producing pet bulk receptacles
An apparatus for producing plastic containers filled with liquids, wherein the plastic containers are closed with a keg fitting and filled with liquid, includes a connection device for connecting a plastic container with a keg fitting. The connection device is configured to move the plastic container relative to the keg fitting. The apparatus includes at least one cleaning device configured to clean at least an area of the keg fitting during at least one of relative movement of the keg fitting with regard to the plastic container and connection of the keg fitting with the plastic container. The cleaning device is configured to supply a cleaning medium to the keg fitting.
US10106388B2 Container processing machine and method for delivering containers to and/or removing them from a container processing machine
A container-processing machine includes a conveyor that rotates about a vertical machine axis, processing stations disposed around the conveyor, a star that delivers unprocessed containers to the conveyor and removes processed containers from the conveyor, and recesses disposed around a periphery of the star for engaging containers. Container transfer occurs by raising a container from a transfer position into a processing position.
US10106387B2 Industrial vehicle
An industrial vehicle includes a hydraulically-operated brake device, a hydraulically-operated loading device, an electric motor, a hydraulic pump, a first hydraulic circuit having an accumulator and a detector for detecting pressure accumulated in the accumulator, a first oil passage connecting the first hydraulic circuit and the hydraulic pump, a load handling device, a second hydraulic circuit having a closed center control valve, a second oil passage connecting the second hydraulic circuit and the hydraulic pump, an oil tank, a pressure compensating circuit, a pilot passage, and a controller. When a selector valve is placed in a first position, hydraulic pressure generated by the hydraulic pump is transmitted to a pressure compensating valve in such a direction that disconnects the hydraulic pump from the oil tank to thereby create in the first oil passage hydraulic pressure that causes the accumulator pressure accumulation.
US10106382B2 Chamber conveyor belt machine
A chamber conveyor belt machine having a machine frame, a chamber cover with two or more columns and a lifting device for lifting the chamber cover. The lifting device may include a safety system that includes a latching rail that cooperates with a latching hook disposed on at least one of the two columns. The safety system may include one or more sensors for determining whether the lifting device is working correctly or is in a failure condition. The safety system may prevent the chamber conveyor belt machine from operating if a failure condition is sensed.
US10106380B2 Cable winch
The invention relates to a cable winch, preferably a sprocket-type large cable winch for deep-sea applications, having a cable drum, the end faces of which are enclosed by end discs, and having at least one drive unit for driving the cable drum. The drive unit comprises a motor and a gear mechanism which on the output side drives an output wheel, said wheel being in engagement with a drive wheel, preferably in the form of a sprocket, provided on one of the end discs. According to the invention, the output wheel of the drive unit is arranged between motor and gear mechanism, and the motor and the gear mechanism extend towards different sides of the end disc.
US10106379B2 Crane superstructure drive device
The invention relates to a drive device for supplying power to multiple engine pumps (4, 5), provided in the superstructure (3) of a mobile crane for superstructure functions, by way of a drive motor (2) arranged in the undercarriage (1) of the mobile crane, comprising a hydraulic motor (7) which is arranged in the superstructure (3) and hydraulically driven by the drive motor (2) and which comprises a first mechanical output which couples at least one first engine pump (4) to the hydraulic motor (7) and a second mechanical output which couples at least one second engine pump (5) to the hydraulic motor (7). The invention also relates to a mobile crane comprising this drive device.
US10106375B1 Split vacuum elevator system
A Split Vacuum Elevator System has a channel connecting a vacuum elevator cylinder or thoroughfare to an electric equipment housing having motors and valves for the operation thereof. The channel is attached at a top of the elevator thoroughfare through a raised protrusion (or more raised protrusions if there are more then one channel) in a sealing plate that is itself attached to the support structure of the thoroughfare. The other side of the channel is connected to an air buffer known as a collector. This collector has one or more protrusions to connect to one or more channels. A raised lip on the collector facilitates the attachment of the housing thereto.
US10106374B2 Method for operating an elevator system and an elevator control device operating in accordance with the method
A method for operating an elevator installation uses an elevator control device, wherein, by at least one sensor allocated to the elevator installation and by a sensor signal obtainable therefrom, a state of the elevator installation is automatically detected by the elevator control device. In dependence on the detected state, the elevator control device automatically generates an activation signal to automatically activate a remote signaling element.
US10106371B2 Controller configured to control allocation of elevator calls based on a group allocation request, a system and a method of performing same
A controller includes a processor configured to, receive, via an input/output (I/O) device, a first destination call having a first departure floor and a first destination floor of a first passenger associated therewith, allocate the first destination call to one of the plurality of elevators, receive, via the I/O device, at least a second destination call having one or more of a second destination floor and a second departure floor of a second passenger associated therewith, and allocate the second destination call to one of the plurality of elevators such that the controller assigns the second destination call to a same one of the plurality of elevators as the first destination call, if a group allocation request associated with the first destination call and the second destination call is received from the link.
US10106370B2 Cable drum transportation and handling apparatus
A cable drum transportation and handling apparatus for mounting, transporting and handling large cable drums includes a supporting structure, which supporting structure may be mounted on a truck or trailer. The apparatus includes stabilizers mounted to the supporting structure, a hydraulics control system and an operator station, a gravity drive having a drive wheel tire for turning the drum to spool cable in or out, and a hydraulic drive system for the gravity drive. An adjustable mechanism ensures firm connection between the tire and a cable drum, when a drum is mounted on the apparatus. A lever arm or bolt pattern puts more or less tension on the gravity drive, for engagement, by moving the drive up and down. Opposing hydraulically-operated lift arms pivotally mounted on an upper part of the supporting structure may be pivoted outwardly and rearwardly. The lift arms laterally close to grasp the drum. Mounts on the end of each arm have a center pin that inserts into the center axis of the drum and a pair of engagement pins that are inserted between the spokes of the drum to assist in holding the drum in place. The apparatus may also include a mounting bracket for a banding cart to hold banding for the cabling.
US10106369B2 Flexible helical cord management device
In one aspect of the present disclosure, a flexible cord management device is provided. The device includes a helical coil base, an s-loop, and a post. The base can be wrapped around at least a portion of a bundled cord. The s-loop includes a first loop and a second loop, where the first loop is coupled to a first end of the base. The first loop can be opened to receive a first end of the bundled cord, such that, the first end of the bundled cord is securely disposed through the first loop. The second loop is coupled to the first loop. The post extends from the first end of the base and can be inserted through the second loop to secure the first loop in a closed position and removed from the second loop to enable the first loop to achieve an open position.
US10106362B2 Method and device for depositing a flexible material web
A method and a device are specified for depositing a flexible material web, wherein the material web (2) is supplied by means of a supply means and deposited in a zigzag shape at a depositing location (2) by means of a laying means, wherein the material web (2) after exiting from the supply means is contacted by at least two engagement elements (5, 6), which can be moved at least in opposite laying directions (A, B), of the laying means and is guided to the depositing location (2). The engagement elements (5, 6) change their position during the contact with the material web (1) between an engagement position (E) and a release position (F), the quality of the deposited material web remaining largely unaffected, because each engagement element (5, 6) has a contact section (7, 8), which can be brought into a contact position (K) in the engagement position (E) and into an idle position (L) in the release position (F), wherein the movement direction (C, D) of the contact section (7, 8) is oriented at a downward angle to the laying direction (A, B).
US10106348B2 Supply unit and image forming apparatus
A supply unit holds a supply unit including a pickup roller for supplying a sheet, enables the supply unit including the pickup roller to be installed into an image forming apparatus, and includes a roller-protecting member. The roller-protecting member has a roller-protecting surface that covers the pickup roller of the supply unit and includes engaging pawls that can engage and integrally hold the supply unit including the pickup roller with the roller-protecting surface covering the pickup roller.
US10106347B2 Feeding mechanism
A feeding mechanism comprises a base body, a feeding roller and a linkage assembly. The base body has a feeding channel. The feeding roller is disposed on the base body, and a part of the feeding roller is located in the feeding channel. The linkage assembly comprises a guiding component and a pressing component. The guiding component is pivotally coupled to the base body. Two ends of the pressing component are respectively and slidably disposed on the base body and the guiding component. The guiding component is rotatable relative to the base body so as to drive the pressing component to move along an extension direction of the feeding channel relative to the guiding component.
US10106340B2 Article loading facility
A control unit performs a first loading control and a second loading control. The first loading control is performed to control a loading operation unit to load a plurality of target articles onto a first supporting member according to arrangement information. The second loading control is performed to execute a second determination process based on at least one of: the arrangement information; detection information obtained by the detection unit; and information regarding a loading area, to determine whether or not the remaining articles are loadable onto the first supporting member, and to control the loading operation unit to load the remaining articles onto the first supporting member if the remaining articles are determined as being loadable in the second determination process. While performing the first loading control, if the control unit does not determine in the first determination process that the target articles are in a different state, the control unit continues performing the first loading control, and while performing the first loading control, if the control unit determines in the first determination process that the target articles are in the different state, the control unit performs the second loading control instead of the first loading control.
US10106339B2 XY table for a linear transport system
A linear transport system can have a carriage guide rail having a first and a second carriage, which are arranged in such a way that they can be moved independently of one another on the carriage guide. The XY table for this linear transport system can comprise a carrying structure and a first and a second linear guide, which are embodied with an angular offset relative to one another and each have a first and a second guide element, e.g., which can be moved relative to one another along a linear track. In one arrangement, the first guide elements of the first and second linear guides are connected to the carrying structure. The second guide element of the second linear guide can be connected to the first carriage and the second guide element of the second linear guide can be connected to the second carriage.
US10106338B2 Material separator for a vertical pneumatic system
A delivery system deposits granular material being pneumatically conveyed within an entraining airflow to sequentially fill a storage silo from bottom to top. The delivery system has a series of vertical tubes and separators, vertically suspended and centered within the silo by a support, for conveying the entrained material upwardly from the bottom to the top of the silo. Each separator selectively separates the material from the airflow by choking the airflow entraining the material therewithin. Each separator automatically selects either to separate the entrained material therewithin and to deposit the separated material therefrom, or else to flow therethrough the entrained material without separation. The support has clamp assemblies, each having clamp halves and clamp brackets, wall brackets, and braces.
US10106337B2 Overhead conveyor system and dip coating line comprising said system
An overhead conveyor system for transporting articles, especially for transporting vehicle bodies, in a treatment line comprises at least one transport carriage which has a fastening device to which at least one article can be fastened. The transport carriage can be displaced along the track by at least one drive means. The transport carriage is designed in such a manner that the fastening device can be transported at least along one section of the track, in a laterally offset manner with respect to the track. The invention further relates to a dip coating line comprising at least one dip-coating tank which can be filled with a treatment liquid, into which tank articles to be treated, especially vehicle bodies, are dipped. A conveying system can displace the articles to be treated towards the dip-coating tank, into the inner edge of the dip-coating tank, out of the dip-coating tank and away therefrom.
US10106334B2 Measurement apparatus, measurement method, and correction method
A measurement apparatus 1 according to the present invention includes a table 10 that has an axis of rotation 14 and supports a disc-shaped object 40, a first driving unit that rotates the table 10 around the axis of rotation 14, a light source 50 that produces illumination light with which an end portion 45 of the disc-shaped object 40 is illuminated, an objective lens 60 that collects the illumination light reflected from the end portion 45, a second driving unit that moves the objective lens 60 along an optical axis 64, an imaging unit 70 that captures an image of the end portion 45 by detecting the reflected light collected by the objective lens 60, and an autofocus optical system 80 that determines a position of the objective lens 60 where the image of the end portion 45 is brought into focus in the imaging unit 70.
US10106331B2 Method for controlling the movement of a transportation unit
In order to be able to plan and control the movement of a transportation unit of a conveying device along a conveying line more easily and more quickly, provision is made so that at least part of the conveying line (2) is assigned at least one logical sector (LSi), wherein the at least one logical sector (LSi) is allocated to one or more conveying segments (FSi) or parts thereof, a movement profile for the transportation unit (TEi) is allocated to the at least one logical sector (LSi), the transportation unit (TEi) is moved in accordance with the specified movement profiles along the at least one logical sector (LSi) and in doing so a new setpoint (S) of the movement is ascertained in each cycle step of the setpoint selection, and the setpoint (S) is transferred via the allocation to one or more conveying segments (FSi), or parts thereof, to the allocated conveying segment(s) (FSi) for adjustment.
US10106323B2 Apparatus for positioning an automated lifting storage cart and related methods
A system for positioning a lifting cart in an automated storage facility is described. In one example, the system includes a motorized lifting cart configured to move about a railway of a storage area. An encoder on the cart reads a property of rotation of a rotating element on the cart, and a controller may receive the property of rotation from the encoder and convert it to a rotation count of the rotating element. The rotating element may be an encoder shaft, drive shaft, and like elements. Some systems include a signal emitter or photo sensor to position the lifting cart and to facilitate providing instructions to the cart.
US10106321B2 Systems and methods for home position and cart acquisition with a materials handling vehicle
A variety of vehicle-based and warehouse-based solutions are provided to increase the adaptability, utility, and efficiency of materials handling vehicles in the warehouse environment, such as a goods storage and retrieval system, comprising a multilevel warehouse racking system, a mobile storage cart, a cart home position, and a materials handling vehicle disposed on a vehicle transit surface and comprising a fork carriage assembly, a navigation subsystem, a cart engagement subsystem, and one or more vehicular controllers to use the navigation subsystem to navigate the materials handling vehicle along the vehicle transit surface to a localized engagement position where the cart home position is within a cart engagement field of view, and use the cart engagement subsystem to engage the mobile storage cart in the cart home position with the fork carriage assembly.
US10106314B2 Holder for sweets
The invention relates to a holder for sweets, having a funnel-shaped handle element and a tray disposed on an expanded part of the handle element, wherein the tray has recesses for containing sweets therein, whereas on ridges separating the individual recesses and/or on the periphery of the tray, spikes for impaling sweets thereon are disposed.
US10106308B2 Evacuated bottle system
An evacuated bottle system including a bottle defining a hollow interior, the bottle having a neck with a rim defining an opening; a cap assembly supported on the bottle, the cap assembly including a funnel having a first portion and a second portion, the first portion being insertable within the interior of the bottle and the second portion engaging a portion of the bottle to support the funnel above the rim, the funnel defining a bore that fluidly communicates with the hollow interior of the bottle; a self-sealing membrane that covers the bore formed by the funnel to selectively seal the hollow interior of the bottle; a cap attachable to the bottle, the cap including a cover portion that extends at least partially over the self-sealing membrane to restrain movement thereof, the cover portion being axially spaced from the self-sealing membrane to define a gap that permits axial movement of the self-sealing membrane to selectively open the bottle to fluid communication outside of the bottle.
US10106300B2 Pour lip closure with drain back
A closure with a drain back for a container of liquids is disclosed. The closure includes a closure body having an upper deck. A skirt depends from the upper deck and is configured to secure to a neck of a container. An inner annular wall depends from the upper deck within the skirt. The inner wall has a downwardly sloped bottom wall with an edge forming an opening therethrough, forming a drain back for liquid into the container. A tubular spout extends from the bottom wall. The spout has a dispensing orifice. The spout and dispensing orifice configured for fluid communication with the container to dispense liquids therefrom. The closure may further include a sealing cap connected to the closure body via a living hinge.
US10106298B2 Outsert for aluminum wine bottle
An aluminum bottle outsert includes an annular inner surface configured to be received and supported on an upper neck portion of an aluminum bottle. The outsert also includes an annular outer surface that has a threaded portion adapted to receive a wine bottle screw top capping assembly.
US10106295B2 Stacked catheter tray, system, and associated methods
A tray stack (100) for accommodating a catheter assembly (1400) and medical devices (1401,1402,1403,1404,1409,1410, 1411,1412,1413) corresponding to catheter use includes a first tray (101) and second tray (102). Each tray (101,102) includes a tray opening, a base member (205,206), and sidewalls (203,204). When placed atop each other, they first tray (101) and second tray (102) form a tray stack (100). When unstacked and placed in a side-by-side, single layer catheter tray assembly (200), implements disposed therein can be arranged in a predetermined sequence corresponding to an order of use during a catheterization procedure. Mechanical couplings (300) can be included to permit the trays to translate with respect to each other. Retention mechanisms (710-713) can be included to hold the trays together.
US10106294B2 Transport rack and/or storage rack, and arrangement of a transport rack and/or storage rack on a floor plate
A transport rack and/or storage rack for standing transport and/or standing storage of plate-shaped goods, such as windows or doors, includes at least two support elements. A standing strip is arranged on a first end of each of the support elements and is removably fastenable, resting on a floor plate. The support elements are connected to each other by at least one crossbar placed on the support elements and the standing strip is aligned perpendicularly to the crossbar. The support elements are single or multi-part plates, having two leaning edges approaching each other at an acute angle away from a base side arranged on the standing strip.
US10106292B2 System of packaging and displaying a set of products
A system of packaging and displaying a set of products is disclosed. The system may include a first and second container, together forming a hinged box, each container including a first display face, and a first back positioned on a side of the container opposite the first display face. A first magnetic element and a second element magnetically responsive to the first magnetic element may be positioned in the containers to assist in closing the box. At least one of the containers includes a transparent cover that secures, even in the open position of the box, displayed products, the displayed product visible through the cover when the box is hinged open. The cover has perforations that can be torn to access the products without tools. The products are arranged in the order of use and installation.
US10106282B2 Device for filling liquid food products
A device for filling liquid to pasty food products into prefabricated individual containers including a support rim, the device including carrier elements which are run by a drive continuously through the device, which carrier elements form receiving openings for the individual containers and include a top side that is oriented away from a direction of gravity and configured to carry the support rim of the individual containers that are inserted into the receiving openings; operating stations in whose operating range the carrier elements move during an endless cycle of the carrier elements in the device; at least one operating station that is configured as a sterilization device which de-germinates the carrier elements and the individual containers; a lifting device forming a portion of the sterilization device and configured to lift individual containers that are seated in the receiving openings and which contact a top side with the support rim.
US10106280B2 Product wrapping unit for a packaging line
A wrapping unit (1) for a packaging line (2) comprises a conveyor (6) for feeding a succession of products (3) in a first direction (7) and a wrapping station (9) arranged along the conveyor (6) for wrapping a film (5) of wrapping material around said products (3), said wrapping station (9) comprising a wrapping device (13) provided with a plurality of wrapping members (15), each of said wrapping members (15) extending in a second direction (11) perpendicular to said first direction (7), said wrapping unit (1) further comprising a stability control group (12) for preventing said products (3) from tipping along said conveyor (6), said stability control group (12) comprising a plurality of anti-tip devices (33), each of said anti-tip devices (33) being associated, during operation, with a respective product (3) to move together with said respective product (3) through said wrapping station (9).
US10106279B2 Film cutter for in-line hay bale wrapper
An in line bale hay bale wrapper with an selective automatic film cutter.
US10106277B2 Self-stabilizing spherical unmanned aerial vehicle camera assembly
A self-stabilizing spherical unmanned aerial vehicle (UAV) camera assembly, including: a stabilizer assembly; a plurality of motors coupled to the stabilizer assembly; a spherical camera mounting cage assembly disposed about and coupled to the stabilizer assembly; and a plurality of cameras coupled to the spherical camera mounting cage assembly. Preferably, the plurality of cameras include a plurality of stereoscopic cameras coupled to an exterior of the spherical camera mounting cage assembly. The self-stabilizing spherical UAV camera assembly is capable of taking/recording 360 degree×180 degree stereoscopic photo/video content. The self-stabilizing spherical UAV camera assembly can also be used with various real-time visualization and control technologies.
US10106272B2 Regenerative activated carbon filtration for aircraft OBIGGS
An onboard aircraft inerting system includes an apparatus and method for regenerating an activated carbon media of a filter module while the aircraft is in flight. In regeneration mode, the activated carbon media is heated to a temperature sufficient to desorb the VOC contaminants adsorbed thereon and the air stream passing through the filter module is at a pressure lower than the air pressure of the air stream passing through the filter in normal inerting mode.
US10106270B2 Automated flight throttle control
Automated throttle control is described herein. One disclosed example method includes calculating, using a processor, a thrust resolver angle based on a flight condition of an aircraft, and controlling a throttle from moving past at least one of the thrust resolver angle or a range defined by the thrust resolver angle to maintain the aircraft in a preferred flight mode.
US10106266B2 Suspension structure for suspending a turboprop having two unducted propellers from a structural element of an aircraft with rigid fastening of the air intake structure
A suspension structure for suspending a turboprop including two unducted propellers from a structural element of an aircraft, the structure including a suspension frame for fastening to a structural element of the aircraft and including a main beam extending parallel to a longitudinal axis of the turboprop, the suspension frame being fastened to an air intake structure of the turboprop by an attachment frame.
US10106265B2 Stabilizer assembly for an aircraft AFT engine
An aerodynamic stabilizer assembly for stabilizing an aft fan mounted to a fuselage of an aircraft is presented. The stabilizer assembly includes one or more generally horizontal stabilizers for mounting to a nacelle of the aft fan and the fuselage so as to stabilize the aft fan. Each of the generally horizontal stabilizers includes an inner portion and an outer portion. The inner portions are mounted to a nacelle of the aft fan and the fuselage at a predetermined downward angle with respect to a central axis of the aft fan so as to direct airflow upwards and into the aft fan, the outer portion being mounted to the inner portion.
US10106256B2 Methods and systems for mass distribution of supply packs
An aerial distribution system and method for deploying items is disclosed. The system includes a box, a lid detachably coupled to the box, a plurality of items within the box, a flexible liner coupled to the box and containing the plurality of items, and at least one strap coupling the lid to the flexible liner. During deployment of the aerial distribution system, air drag removes the lid from the box and inverts the flexible liner to eject the plurality of items from the box.
US10106246B2 Fluid systems that include a co-flow jet
Fluid systems are described. An example fluid system has a first body portion, a second body portion, a spacer, and a fluid pressurizer. The first body portion and the second body portion cooperatively define an injection opening, a suction opening, and a channel that extends from the injection opening to the suction opening. The fluid pressurizer is disposed within the channel cooperatively defined by the first body portion and the second body portion. The first body portion defines a cavity that is sized and configured to filter debris that enters the channel during use and provide a mechanism for removing the debris from the system.
US10106245B2 Automatic flight control actuator systems
Automatic flight control actuator systems are provided. In one example, the system includes a pilot input linkage that receives an input and a flight surface output linkage adapted to control a flight surface. The system also includes a strain wave gear including a flex spline coupled to one of the pilot input linkage and the flight surface output linkage. The strain wave gear further includes a circular spline coupled to the other of the flight surface output linkage and the pilot input linkage, and coupled to the flex spline such that the input from the pilot input linkage is transferred to the flight surface output linkage via the strain wave gear.
US10106242B1 Mechanically attached thermal protection system
A mechanically attached thermal protection system (MATPS) includes an insulating tile having a top surface, a bottom surface, and a plurality of access holes that extend through the insulating tile from the top surface to the bottom surface. A plurality of brackets include a first end attached to the insulating tile and a second end including a mounting hole therethrough, the second end being positioned proximate the bottom surface of the insulating tile. A plurality of fasteners are positioned proximate the bottom surface of the insulating tile and at least partially positioned within one of the access holes so as to be accessible from the top surface of the insulating tile through one of the plurality of access holes. A MATPS including a plurality of air channels within the insulating tile and a method for sealing these air channels to those within an adjacent structure is also described herein.
US10106240B2 Pinned fuselage-to-wing connection
An aircraft comprises a fuselage, a wing assembly, and a pinned fuselage-to-wing connection including a forward pin joint, an aft pin joint, and intermediate pin joints between the forward and aft pin joints. The intermediate pin joints have pins aligned in an axial direction and are configured to slide along the axial direction without transferring axial loads from the wing assembly to the fuselage. At least one of the forward and aft pin joints is constrained to prevent translation along the axial direction.
US10106239B2 Aircraft based non-dedicated special mission pod mounting apparatus
Particular embodiments include a non-dedicated, temporarily installed, airborne special mission payload mounting system which is mechanically interfaced to the Air Deployment System (ADS) rails of a host cargo aircraft. An Adaptive Mounting System (AMS) plate is placed over an ADS rail section and restrained in position. Once the AMS plate is secured, an articulated or fixed position strut can be attached to the AMS plate through the opened side doorway without removing the original door. A removable load transfer brace (LTB) can be coupled from the AMS plate inboard to the floor of the aircraft. The LTB is hinged to the AMS plate, and can be disconnected from the floor of the aircraft and rotated to a vertical position from the AMS plate.
US10106234B2 High speed triangular shaped hydroplaning monohull craft with aircraft-like control surfaces having surface adhesion hull characteristics
The invention is an air propelled boat that has a triangular shaped hydroplaning monohull which has surface adhesion characteristics by means of a concave bottom hull. The invention also has aircraft-like control surfaces (5,6) for safety and control at high speeds. The invention is the only monohull marine craft which produces aerodynamic lift without wings and has air based propulsion (4), air based control surfaces and a unique concave planing hull.
US10106233B2 Autonomous unmanned underwater vehicles
Autonomous underwater vehicles are described that are stackable with other like autonomous underwater vehicles on a suitable launch platform, such as within a vertical missile launch tube of a submarine, waiting to be deployed into the water. The underwater vehicles can be deployed or launched individually, in groups, or all together into the water. While stacked together, the stacked autonomous underwater vehicles can connect to one another or to external structure of the launch platform. In addition, the underwater vehicles can be positively buoyant or can be made to have controllable buoyancy to allow the underwater vehicles to float up and out of the launch platform during deployment without an external deployment force.
US10106232B2 Fastening assembly of a fire door to a bulkhead
A fastening assembly of a fire door to a bulkhead includes a shaped frame, to which is hinged the door, which includes a first bracket facing at least in part a first side surface of the bulkhead, and a primary flange, mechanically connected to the first bracket. The fastening assembly has a subframe, which in turn includes a second bracket, parallel to the first bracket and facing a second side surface of the bulkhead, and at least one secondary flange, mechanically connected to the second bracket. At least one joint mutually connects the frame and the subframe, to retain the bulkhead between the first and the second bracket mutually facing, without engaging simultaneously the bulkhead the portion of the first bracket facing the first side surface and the portion of the second bracket facing the second side surface.
US10106230B2 Biomimic design stabilizing fin or keel for surface planing or submerged watercraft
A stabilizing fin or keel utilizing biomimic design features for use on surface planing or submerged watercraft to provide increased dimensional stability, control and efficiency.
US10106225B1 Hull for a watercraft
A hull for a watercraft and a watercraft disclosed, the hull including a hull body having a first recess surface defining a first recess, and a second recess surface defining a second recess; a first hull panel disposed in the first recess, a front portion of the first hull panel being movable between a first and second position; a second hull panel disposed in the second recess, a front portion of the second hull panel being movable between a third and fourth position; a first biasing member biasing the front portion of the first hull panel toward the first position; a second biasing member biasing the front portion of the second hull panel toward the third position; a first stopper for the first hull panel; a second stopper for the second hull panel; and a stabilizing bar for transferring motion between the first hull panel and the second hull panel.
US10106224B2 Front derailleur device for a bicycle chain shift
A front derailleur device for a bicycle chain shift includes a frame fixing part for attachment to a bicycle frame, a hinge arrangement which is pivotable relative to the frame fixing part, and a chain cage which is pivotable relative to the frame fixing part via the pivotable hinge arrangement for guiding and pivoting of the bicycle chain. The hinge arrangement includes at least two hinged struts which can be mounted rotatably relative to the frame fixing part and relative to the chain cage about pivot axes. The pivot axes run substantially parallel to each other and, in a mounted state of the derailleur device on a bicycle, may be oriented substantially vertically.
US10106223B2 Bicycle control system
A bicycle control system is provided that is configured to control a bicycle component using a threshold value that is appropriate for the rider. The bicycle control system includes a controller for controlling a bicycle component based on a threshold value and a parameter related to a running state of a bicycle. The controller changes the threshold value when an operating unit is operated, and the change amount of the threshold value when the operating unit is operated is determined based on an operating state of the operating unit.
US10106222B1 Pedal apparatus with actuator configured to apply variable pressures
In one example aspect, a pedal apparatus is disclosed. The pedal apparatus may include a first portion. The first portion may be configured to secure a second portion that may be attached to a footwear. The first portion may be different than the second portion. The pedal apparatus may also include at least one actuator that may be configured to apply one or more variable pressures on the second portion, which may be based one or more movements of the first portion.
US10106221B2 Bicycle rear wheel suspension system
A bicycle frame assembly having a number of rotatable members configured to absorb shocks and impacts associated with operation of the bicycle. The assembly includes a frame constructed to support a rider and a chain stay having a rearward end that extends toward a wheel hub and a forward end that is pivotably connected to the frame. An absorber is pivotably connected to the forward end of the chain stay and extends to a rocker arm that is pivotably connected to the frame. A seat stay is pivotably connected to a rearward end of the rocker arm and extends to the rearward end of the chain stay. The rearward ends of the seat stay and the chain stay are pivotably connected to rotate about a common axis.
US10106219B2 Cowl stay structure for vehicle, and vehicle including same
In a cowl stay structure for a vehicle which is mounted on a front end part of a body frame having a pair of main frames extending longitudinally to the left and right, and which supports a cowling, a cowl stay supporting the cowling has a front opening which serves as a duct with a hollow structure designed to guide the air taken in from a front side of a vehicle body to an air cleaner box. The cowl stay is mounted on a front surface of a head pipe arranged on the front end of the body frame for establishing a flow path of the front opening with said head pipe opening. A headlight configured to irradiate an area in front of a vehicle with light is placed inside the cowl stay. Such a cowl stay structure has reduced size and weight, and it supports multiple parts.
US10106218B2 Vehicle tilting system and tricycle
A vehicle tilting system is used for a tricycle. The tricycle has a front body and a rear body. The front body has a front wheel. The rear body has two rear wheels. The vehicle tilting system has a track assembly and a sliding base assembly. The track assembly is arcuate in shape. The sliding base assembly slides on the track assembly.
US10106216B2 Bicycle seatpost assembly with cable connecting device
A first cylinder, a second cylinder configured to be telescopically received therein are provided, a positioner configured to relatively position the first cylinder and the second cylinder, an operator configured to be mounted to a bicycle and operatively coupled to the positioner, and a control cable. The control cable may include an outer casing, a first cable having a first end and a second end and configured to be operatively connected to the positioner at the first end, and a second cable having a third end and a fourth end. The second cable may be configured to be operatively connected to the operator at the third end. A cable connector may be configured to connect the second end of the first cable and the fourth end of the second cable.
US10106213B2 Articulating cart system
An articulating cart system which utilizes an articulating frame to effectively maneuver within tight spaces and a low-elevation platform to ease mounting and dismounting the cart. The articulating cart system generally includes a front frame and a rear frame. A platform is connected to the front frame so that the platform pivots or articulates along with the front frame with respect to the rear frame. A joystick controller may be provided which allows one-handed operation. One or more actuators may be connected between the rear frame and the front frame for pivoting the front frame with respect to the rear frame. A motor is provided to power the actuators and frame wheels. The platform is close to the ground to ease access for the operator. Utilizing the articulating frame, the present invention may traverse much tighter spaces and turns than is possible with previous cart systems.
US10106210B2 Compact efficient system to quickly raise and slowly lower an air dam
A front air dam assembly for a vehicle includes a translatable front air deflecting panel for altering an airflow beneath the vehicle, a deploying mechanism for translating the front air deflecting panel between a raised position and one or more deployed positions, and a rapid raising mechanism for rapidly raising the front air deflecting panel from the one or more deployed positions. A controller in operative communication with the deploying mechanism and the rapid raising mechanism controls the operation thereof. At least one sensor is included for sending a signal indicative of a road or vehicle condition to the controller. A locking mechanism under the control of the controller is provided for locking the front air deflector panel in the raised or the one or more deployed position.
US10106209B2 Rail assemblies for trailers
Two-piece rail assemblies for truck trailers are provided. The two piece rail assemblies may include: a first rail configured with a first straight edge, and a second rail configured with a second straight edge coupled to the first straight edge of the first rail and configured with a curved edge to receive a cambered roof panel.
US10106206B1 Structural storage compartment in a vehicle cabin
An autonomous vehicle can include a front seat facing rearward, and a rear seat facing forward. This provides a common foot or leg area between the seats that face each other. The vehicle includes a body that has a pair of opposing B-pillars. A support beam extends through the common leg area, between the front and rear seats, and mounts to the B-pillars. The support beam provides direct structural support to the B-pillars. A luggage compartment is coupled to the support beam and extends between the B-pillars. The luggage compartment has access openings that face forward and rearward, allowing the forward and rearward passengers to store luggage.
US10106205B2 Reinforcement structure
A structural reinforcement comprising a base reinforcing structure including a plurality of ribs and having a first surface and a second surface, an expandable adhesive material located onto a first portion of the first surface, and a sealant material located around an edge of the second surface, the second surface being substantially free of any of the plurality of ribs.
US10106196B2 Vehicle rear section structure
A vehicle rear section structure includes: left and right rear side members disposed along a front-rear direction at width direction sides of a rear floor pan; a rear suspension member extending along the vehicle front-rear direction, and attached to front portions of left and right rear side members; a load bearing section projecting upwardly from the rear suspension member; left and right reinforcement members extending along the vehicle front-rear direction, and disposed at a vehicle width direction inner side of rear portions of the left and right rear side members and at a vehicle rear side of the rear suspension member, a rear end portion of the reinforcement member partially overlapping a rear bumper reinforcement in a vehicle front-rear direction view; and a rear cross member linking the left and right rear side members together and partially overlapping the load bearing section in the vehicle front-rear direction view.
US10106195B2 Pin indexable sleeve for select wheel alignment correction
A system for wheel alignment is provided including adjustments to camber, toe, and thrust. A sleeve is fitted over the spindle of an axle. Rotation of the sleeve relative to the spindle provides for adjustments to wheel alignment while a locking feature such as e.g., a pin, is used to maintain the selected position of the sleeve relative to the spindle. The available positions of the sleeve relative to the spindle are predetermined in order to provide for discrete, known adjustments to the alignment of the wheel.
US10106194B2 Display apparatus and vehicle having the same
A display apparatus, a vehicle including the same, includes a sensor unit configured to acquire vehicle periphery information, and an interface unit configured to acquire vehicle state information. The display apparatus also includes a display unit configured to display a first indicator indicating a target steering direction, a third indicator indicating a current steering state, and a second indicator displayed at a position between the first indicator and the third indicator. The display apparatus also includes a processor configured to determine the target steering direction based on the vehicle state information and the vehicle periphery information.
US10106188B2 Steering wheel cooling system
Disclosed is a steering wheel having cooling system inside. A steering wheel includes a hub connected to a steering column, a rim provided with a hollow formed therein and spokes configured to connect the hub and the rim. Cooling units located at the hub or the spokes of the steering wheel is provided to supply cooling air. Heat pipes thermally connect the cooling units and the rim of the steering wheel.
US10106187B1 Baby carrier device
A baby carrier device has a main body operably mounted on pairs of front and rear leg assembles. The main body includes a middle body portion, a front body portion pivotally mounted on a front of the middle body portion with a pair of forward pivots, and a rear body portion that is pivotally mounted on a rear of the middle body portion via a pair of rear pivots. The pair of front leg assemblies are pivotally mounted on the forward pivots and extend to a wheel. The pair of rear leg assemblies are pivotally mounted on the rear pivots and extend to a wheel. A handle assembly is also pivotally mounted on the main body.
US10106185B2 Collapsible stroller with trigger handle
A collapsible stroller is disclosed, including a front axle frame member, a rear axle frame member, a handlebar frame member, a handlebar, and a hub. The hub includes a rotating attachment point for the front axle frame member, a rotating attachment point for the handlebar frame member, a fixed attachment point for the rear axle frame member. A cable connects the hub, and a rotatable handle on the handlebar frame member. When the rotatable handle is rotated, the cable causes the hub to collapse in two stages.
US10106172B2 Shared vehicle system
A selection for a shared vehicle is received. Whether the shared vehicle is in view of a user device camera is determined. At least one of directions to the shared vehicle are provided to the user device. Data of the shared vehicle are identified.
US10106171B2 Vehicle control module with signal switchboard and output tables
A control module capable of operating on one of first and second vehicles can include a) a module output table comprising a superset of module output elements comprising a first subset of module output elements related to a first set of hardware devices provided on the first vehicle and a second subset of module output elements related to a second set of hardware devices provided on the second vehicle; b) vehicle function output elements related to vehicle function outputs utilized on the first and second vehicles; and c) a configuration table comprising configuration elements corresponding to the module output elements. The module can also include computer-based structure for determining a value of a vehicle function output element corresponding to a module output element of the module output table, transforming the value to the transformed value, and storing the transformed value based on the corresponding module output element.
US10106170B2 Vehicle ramp control system
A vehicle ramp control system may include a system controller configured to interface with a power ramp system for a vehicle and with an OEM vehicle control system. A service tool configured to interface with the system controller is programmed to exchange with the system controller data relating to at least one operational aspect of the power ramp system. A diagnostic tool configured to interface with the system controller is programmed to exchange with the system controller data relating to at least one diagnostic aspect of the power ramp system. A preventative maintenance indicator operatively associated with the system controller is activated by the system controller when a preventative maintenance operation is required.
US10106169B2 Method for monitoring a motor vehicle
A method for monitoring a motor vehicle on the basis of one or more comparison values of a variable relating to a motion of the motor vehicle which have respectively been ascertained with different, motor-vehicle-external capture devices, a functionality in the context of ascertaining the variable with motor-vehicle-internal capture device, and/or a functionality of a drive control system of the motor vehicle, being assessed on the basis of the comparison values.
US10106167B2 Control system and method for determining an irregularity of a road surface
Control system, which is adapted for application in a vehicle and intended to recognize vehicles driving in front on the basis of environmental data which are obtained from at least one environmental sensor (110) disposed on the vehicle. The at least one environmental sensor (110) is adapted to provide an electronic controller (200) of the control system with the environmental data which reflect the area (115) in front of the vehicle. The control system is at least adapted and intended to detect another vehicle (alter) participating in traffic in front of the own vehicle (ego) with the at least one environmental sensor (110) during a predetermined time period or continuously and to recognize a position change of the other vehicle (alter). If a position change of the other vehicle (alter) is recognized, a signal (255) is output, which is suitable to warn a driver of the own vehicle (ego) of an irregularity in the road surface and/or to adjust a speed and/or a vehicle setting of the own vehicle (ego).
US10106157B2 Vehicle control apparatus and vehicle control method
A vehicle control apparatus detects an object in a travel direction of a vehicle. The vehicle control apparatus restrains a drive force of the vehicle when an object is detected. The vehicle control apparatus acquires a jerk in a travel direction on the basis of a behavior of the vehicle. When an accelerator of the vehicle is actuated while the vehicle is in a state in which the drive force of the vehicle is restrained, and a speed of the vehicle is lower than a predetermined value. The vehicle control apparatus increases the drive force, and decreases a post-increase drive force on the basis of the acquired jerk.
US10106155B2 Vehicular camera with on-board microcontroller
A vehicular camera includes a lens, an image processor configured to receive images from the lens, and a microcontroller containing flash memory. The microcontroller is connected to the image processor by a first bus through which command data is communicated to the image processor from the microcontroller. The command data includes application instructions to draw application data from a selected point in the flash memory. The microcontroller is connected to the image processor by a second bus through which application data is communicated to the image processor from the flash memory.
US10106154B2 Driving support apparatus
A driving support apparatus according to the invention estimates the position of a moving body by controlling a position estimation unit when the tracking-target moving body leaves a first area or a second area to enter a blind spot area and detects the position of the moving body by controlling a position detection unit when the moving body leaves the blind spot area to enter the first area or the second area. In this manner, the trajectory of the tracking-target moving body is calculated so that the trajectory of the moving body detected in the first area or the second area and the trajectory of the moving body estimated in the blind spot area are continuous to each other and driving support is executed based on the calculated trajectory of the tracking-target moving body.
US10106146B2 Method and system for torque control
Methods and systems are provided for reducing torque pulsations during hybrid engine shutdown and restarts. A valve actuating mechanism may be actuated to operate an engine with a selected valve lift profile during engine restart and shutdown events that is distinct from the valve lift profile applied during cylinder combustion. The selected valve lift profile reduces cylinder pressure during engine shutdown and restarts.
US10106144B2 Vehicle comprising a vehicle system controller for controlling energy flows within the vehicle
A vehicle system controller is configured to determine a current buffer ratio for a first energy buffer based on a current buffer energy level for the first energy buffer and a predetermined buffer range for the first energy buffer, and determine if the current buffer ratio for the first energy buffer should be increased using energy provided by a power converter, the determination being based on the current buffer ratio for the first energy buffer and a cost for generating energy from energy stored in a second energy buffer using the power converter.
US10106142B2 Method and apparatus to monitor a temperature sensor
A powertrain system including an engine and transmission is described, and includes a temperature sensor disposed to monitor a hydraulic fluid for the transmission. A method for monitoring the temperature sensor includes monitoring engine operation including engine coolant temperature and monitoring a signal output from the temperature sensor. An indicated temperature slope is determined based upon the signal output from the temperature sensor, and a temperature region associated with the engine coolant temperature is determined. Performance of the temperature sensor is evaluated based upon the indicated temperature slope and minimum and maximum temperature slope thresholds that are associated with the temperature region.
US10106139B2 Brake systems and methods
A hydraulic brake valve system may comprise a valve housing comprising a brake port, a pressure port, a return port, and a valve actuation end; a valve shaft coupled to the valve actuation end, wherein the valve shaft may be comprised at least partially within the valve housing; and an electric actuator coupled to the valve shaft, wherein the electric actuator may be configured to move the valve shaft between a shaft on position and a shaft off position. The hydraulic brake valve system may be configured to pass hydraulic pressure through at least one of the brake port, the pressure port, or the return port in response to a position of the valve shaft.
US10106138B2 Brake system
In one embodiment of the brake system, the control unit executes a fluid suction control to suck in the brake fluid from the supply line. The control unit determines whether or not the fluid suction control needs to be executed, and in the event that the control unit determines that the fluid suction control needs to be executed, the control unit is configured to close the cutoff valve and control the electric actuator to drive the slave cylinder in a depressurizing direction.
US10106137B2 Adjustment of maximum brake pump speed based on rate of change of target deceleration
Method and apparatus are disclosed for adjustment of maximum brake pump speed based on target and measured decelerations. An example vehicle includes a brake pump having a maximum pump speed. The example vehicle also includes a vehicle decelerator to determine a target deceleration for autonomous deceleration and send a signal to the brake pump to decelerate the vehicle at the target deceleration. The example vehicle also includes a first sensor to detect a measured deceleration and a maximum speed regulator to adjust the maximum pump speed based on a difference between the target deceleration and the measured deceleration.
US10106130B2 Device for lateral spraying of a washing liquid for a wiper arm for a system for wiping a pane of a motor vehicle
The invention relates to a device (11) for lateral spraying of a washing liquid designed to be attached to a windscreen wiper arm (3) of a system for wiping a pane of a motor vehicle, characterized in that it comprises a supply cannula (35), a duct for distributing the liquid (39) and at least two nozzles (28) for spraying the liquid, the nozzles (28) and the supply cannula (35) being fluidically connected via the intermediary of the distribution duct (39), characterized in that the nozzles (28) are arranged on either side of an axis (A) defined by the supply cannula (35).The invention also relates to a wiper arm (3) for a system for wiping a pane of a motor vehicle, comprising a lateral spraying device (11) such that it is possible to spray on each lateral side of the arm.
US10106129B2 Windscreen wiper
The invention relates to a support mount (10) for a windscreen wiper, said mount (10) comprising a body of longitudinal principal orientation (X), said body comprising first means designed to receive a curving vertebra (20) and second means designed to hold a deflector (30) of said wiper, characterized in that said second means comprise notches (50) making it easier for said vertebra to curve.The invention also relates to a windscreen wiper comprising such a mount (10).The invention also relates to a wiping system comprising such a wiper.
US10106127B2 Wiper system with variable sweep angle motor drive
A windshield wiper system for an aircraft is provided and includes a motor, an output shaft, a wrap spring and crank rocker mechanism (WSCRM) to which the motor and the output shaft are coupled and a controller. By way of the WSCRM, first directional rotation input to the WSCRM from the motor via a two-stage gear reduction is converted such that the output shaft drives wiper blade oscillation through a first sweep angle and second directional rotation input to the WSCRM from the motor is converted such that the output shaft drives wiper blade oscillation through a second sweep angle. The controller is configured to control the motor such that the first directional rotation is continuously or non-continuously input during first or second flight conditions, respectively, and the second directional rotation is continuously input during third flight conditions.
US10106126B2 Apparatus and method for detecting precipitation for a motor vehicle
An apparatus and a method are for detecting precipitation on a windscreen of a motor vehicle. A camera device records a first image and thereafter a second image. A comparison device produces a first comparison image by comparing the first image with the second image. An image detection device identifies objects on the first comparison image, and determines motion of the objects, to detect whether there is precipitation on the windscreen.
US10106123B2 Firing mechanism
A firing mechanism (25) for activation of a pneumatic stored energy system having a motor (50) connected to a vessel (20) by a tether, the vessel (20) containing a pressurized fluid. Activation of the motor (50) causes the tether to wind, applying a linear force to an attachment region of the vessel, fracturing the vessel (20) to release the pressurized fluid thereby activating the pneumatic stored energy system.
US10106122B2 Folding preparation body of driver seat airbag and folding method of folded body
A folding preparation body includes a pre-folded portion folded in a folded shape of being gathered to an upper side of the inflow opening and mounted in the steering wheel, the pre-folded portion includes a portion in which the front edge of the initial preparation body is folded to approach the inflow opening in the vehicle body side wall, the vehicle body side wall of the folding preparation body includes a non-folded portion from the inflow opening to a crease of the pre-folded portion and a folded portion which is folded from the crease to be overlapped on the lower surface of the non-folded portion, and the pre-folded portion includes the folded portion of the vehicle body side wall and a lower surface side portion, which covers an outer surface of the folded portion, in the cover portion of the driver side wall.
US10106119B2 Curtain airbag for vehicle
A curtain airbag for a vehicle may include a curtain airbag cushion including a rear panel disposed at a door window side of the vehicle and a front panel disposed inside the vehicle, a protrusion formed by bending the curtain airbag cushion to protrude toward the inside of the vehicle, and connections for attaching upper and lower ends of a protruding part of the protrusion.
US10106114B2 Quick release grill guard and associated systems and methods
The disclosed apparatus, systems and methods relate to a quick release grill guard further comprising at least one latching system configured for the quick release and pivot of the grill guard away from the vehicle grill face. In certain embodiments, the quick release grill guard further comprises a grill guard coupling portion, a vehicle coupling portion, a latching portion a hinge, a quick release bar; and a clasping member. In certain embodiments, the grill guard coupling portion is capable of being freely pivoted relative to the hinge by actuation of the clasping member by way of the quick release bar. In exemplary embodiments, the quick release bar is in operable communication with multiple latching systems so as to release the grill guard in a plurality of locations simultaneously.
US10106113B2 Hollow profiled element having depressions
A hollow profiled element, includes a plurality of longitudinal edges, which extend in a longitudinal direction and are connected by side walls, wherein a longitudinal edge has at least one depression, the depression base of which extends transversely to the longitudinal direction and at an angle to the side walls forming the longitudinal edge. According to an embodiment of the invention, a side wall forming the longitudinal edge has a transversely extending bulge in the region of the depression, wherein the depression base transitions at the end into the bulge in the region of said side wall and the bulge is designed with a shape that has a convex form in the transition to the depression and drops to the level of the side wall before an opposite longitudinal edge is reached.
US10106107B2 Waterproof type control unit and waterproof type control unit manufacturing method
A peripheral wall includes a first peripheral wall edge portion and a second peripheral wall edge portion, which are disposed on a case member bottom surface so as to be distant from each other. A connector member main unit is disposed in a space between the first and second peripheral wall edge portions. A peripheral wall groove, which is open toward the connector member main unit, is disposed in each of the first and second peripheral wall edge portions. A bottom surface of the peripheral wall groove is inclined with respect to the case member bottom surface. A base plate groove is disposed on the bottom surface of the case member. A seal material is filled into the space formed between each of an inner surface of the peripheral wall groove and an inner surface of the base plate groove, and the connector member.
US10106105B2 Cup holder assembly
A receptacle for a vehicle interior is configured to provide light from a light source. The receptacle includes a base, a wall extending from the base to form an opening and providing an outlet into the opening, a guide for transmitting light along the base, and a guide for transmitting light along the wall. When light is provided beneath the base by the light source, light is transmitted through the guide along the base and into the guide along the wall.
US10106101B2 Motor-vehicle operating device having a resiliently mounted actuating element and operating haptics
A housing, an actuating element, and a spring element are included in an operating device for a motor vehicle. The housing fastens the operating device. The actuating element is mounted for translatory deflection from a resting position with respect to the housing by the application of an actuating force. The spring element is resiliently mounted and a restoring force is applied to the actuating element in the direction of the resting position in the event of the translatory deflection. The spring element can be a plate or a strip and is supported by at least two supporting elements so as to be immovable with respect to the housing at respective support points. An intermediate region is defined between the support points and the actuating element lies against the spring element at two opposite ends of the spring element outside of the intermediate region.
US10106100B1 Secure latch for coupled assemblies
A latch pivots about and slides axially on an axle on a second assembly. It is manually pulled axially outward against a spring to clear and pivot over a boss on a first assembly. It then slides over the boss via a boss receiving hole in the latch, interconnecting the two assemblies. A spring urges the latch inward, retaining it on the boss. A hole for a shackle may be provided in the first assembly and in the latch to lock the latch in the connected position. The latch may pivot to a retracted position over a shackle hole in the second assembly to store a lock on the second assembly. It prevents separation of two assemblies that are coupled by a pivoting engagement of one assembly relative to the other.
US10106092B2 Expandable and reconfigurable console
A center console includes a base and a bin supported on the base. The bin has a first section and a second section that define a variable volume storage compartment.
US10106091B2 Support for a portable electronic apparatus, particularly in a vehicle, set comprising such a support and an electronic apparatus, associated retention process
A support for a portable electronic apparatus. The support includes a first edge and a second edge, a locking device movable between a locking position, in which it prevents the translation of the first edge relative to the second edge, and an unlocking position, and an actuating device for actuating the locking device movable between an inactive position and an active position in which the actuating device keeps the locking device in its unlocking position. Movement of the second edge from an idle position to a maintaining position drives the actuating device from its active position to its inactive position. The support includes a control device that, when moved from a released position to a disengagement position, causes the actuating device to go from its inactive position to its active position while keeping the second edge in its maintaining position.
US10106088B2 Automated retractable vehicle step
Powered retractable vehicle step assist systems and methods are provided. The steps systems are configured for installation (e.g., after market installation) and use with a vehicle. The system can include a stepping member movable between a retracted position and a deployed position with respect to the vehicle. The system can further include a vehicle interface configured to electronically communicate with an existing communication bus of the vehicle, such as through a connection with an existing electronics port of the vehicle. A controller of the step system can be configured to process information received from the vehicle interface and, based at least partly on the processing of the information, cause movement of the stepping member between the retracted position and the deployed position.
US10106087B2 Detachable workpiece support apparatus for a tailgate step
A workpiece support is provided for a pickup truck tailgate. The tailgate includes a retractable step including a pair of step support members. The attachment brackets include a workpiece support bar and a riser that are attached to the step support members and to each other at a right angle. The workpiece support bar and riser may be fixedly attached to each other or attached by a pivot connector. Detachable connectors are provided to connect a workpiece support bar and riser detachably to the step support members.
US10106086B1 Pillar mounted assist step
A structure for a vehicle includes a lower frame member and an upper frame member. A pillar extends from the lower frame member to the upper frame member and a step is carried by the pillar between the lower frame member and upper frame member.
US10106085B2 Vehicle side and rear monitoring system with fail-safe function and method thereof
A vehicle side and rear monitoring system with a fail-safe function and a method thereof are provided. The system provides a fail-safe function for safe driving of a vehicle when an abnormality occurs in a side monitoring system of the vehicle, and a technique that provides a continuous side field of view of the vehicle when an abnormality occurs in the side monitoring system in the vehicle equipped with an AVM system. In addition, the system and provides a technique that corrects the distortion of an image captured by an AVM camera and performs an image rotation transformation to provide the image captured by the AVM camera at the same angle as that provided by side-view cameras. Therefore, when an abnormality occurs in the side monitoring system, the vehicle side and rear monitoring system with a fail-safe function continuously provides the same image as captured by the side-view cameras.
US10106084B2 Vehicle-mounted display system and vehicle
The present disclosure provides a vehicle-mounted display system and a vehicle. The vehicle-mounted display system includes a transparent projection screen and a projector configured to project an image onto the transparent projection screen. A first polarizer is attached onto a lens of the projector, and a second polarizer is attached onto the transparent projection screen. The second polarizer has a polarization transmission direction crossing a polarization transmission direction of the first polarizer at such an angle as to enable a light beam from the projector and passing through the first polarizer and the second polarizer to be of an intensity smaller than an intensity of a light beam capable of being recognized by human eyes. The second polarizer has a polarization reflection direction perpendicular to its polarization transmission direction, so as to reflect a light component in the polarization reflection direction.
US10106082B2 System and method for warning of an imminent collision between a towing vehicle and its trailer when reversing
A system for warning of an imminent collision between a towing vehicle (2) and a trailer (3) when reversing includes an arrangement for providing a warning signal to a driver of the vehicle dependent on an angle between a longitudinal axis of the towing vehicle (2) and a longitudinal axis of the trailer (3), when there is the threat of a collision between the towing vehicle (2) and the trailer (3) while reversing.
US10106078B1 Vehicle lamp assembly
A vehicle overhead console is provided herein. The vehicle overhead console includes a housing and a substrate defining a cavity therebetween. A light source is within the cavity. A reflector has a first end portion that surrounds the light source and a second end portion proximate a first lens. A trim member has a thickness that varies laterally. A second lens is offset from the first lens.
US10106076B2 Three mode police mirror
A warning indicator system for a vehicle side-view mirror includes light sources disposed to emit light in patterns and/or colors visible through a partially light-reflective surface. One or more processors are operatively configured to actuate the light sources in predetermined sequences defining a stealth mode, a pursuit mode, and a traffic advisor mode. The partially light-reflective surface may be a light transmitting substrate having a coating of a reflective substance provided in a thickness allowing at least a partial transmission of light therethrough. The light sources may be printed light-emitting diodes (LEDs). Disposing the light sources in desired patterns to emit desired colors on actuation in a predetermined sequence allows configuring the side mirrors to emit visible light signals indicative of the stealth mode, a pursuit mode, and a traffic advisor mode.
US10106070B2 Bed lift
A vehicle includes a bed that is movable upward from a lowered position where the bed is positioned to receive one or more persons to sleep thereon to a stowed position where at least a portion of the bed is stowed adjacent to a ceiling of the vehicle. The portion of the bed can be at least substantially horizontal and horizontally offset when the bed is in the lowered position and the stowed position. The bed can also be positioned above a seating area in the vehicle and moved upward with one or more screw drive members or one or more straps.
US10106066B2 Head restraint system
The present invention describes a head restraint system for a vehicle. The head restrained system comprises a head restraint cushion connected to headrest rods. The swivel mechanism comprises swivel rods, dampers and springs. The angular movement of the head restraint cushion is controlled by the damper movement on application of load on the head restrained cushion, where the damper movement is based on the amplitude and duration of load being applied on head restrained cushion. Another embodiment of the present invention describes a head restraint system comprising a movable assembly and a stationary assembly. The movable assembly comprises slotted guide plate, flat plate and slotted guide column. The stationary assembly comprises guide rod, and linear guide way. The movable assembly and stationary assembly are connected using a linear damping unit, where the linear damping unit is placed inside the slotted guide column.
US10106064B2 Seat pad
Providing a seat pad that can provide good sitting comfortability with bonding between a ventilation member and an expanded resin foam included in the seat pad ensured.A seat pad 10 including a ventilation member 20 having a function that lets air through to/from an outside, the seat pad 10 being formed by integral expansion molding of an expandable resin material M with the ventilation member 20 introduced therein, includes a covering member 30 that covers at least a part of the ventilation member 20 at an interface between the ventilation member 20 and the expandable resin material M, and the covering member 30 includes an impregnation inhibiting material having a function that inhibits infiltration of the expandable resin material M, the function being at least higher than that of the ventilation member 20.
US10106059B2 Harmonic drive disc recliner for automotive vehicle seat
A disc recliner 18 for a seat assembly includes a fixed plate 22 secured to a seat cushion 12 and a rotatable plate 30 secured to a seat back 14. Each of the fixed and rotatable plates 22,30 has a plurality of teeth 40,48, the number of teeth not being equal. A flex spline 26 has a plurality of teeth 52, the number of teeth being equal to the number of teeth on the fixed plate 22. A wave generator 28 causes a portion of the teeth 52 on the flex spline 26 to meshingly engage with the teeth 40,48 on the fixed and rotatable plates 22,30. Rotation of the wave generator 28 causes the teeth 52 on the flex spline 26 which meshingly engage with the teeth 40,48 on the fixed and rotatable plates 22,30 to change, thereby causing the rotatable plate 30 to rotate relative to the fixed plate 22, which in turn causes the seat back 14 to pivot relative to the seat cushion 12.
US10106058B2 Vehicle seat
A vehicle seat includes a cushion frame, a base portion, and a guide structure. The guide structure includes a rail and a rolling mechanism. The rolling mechanism includes an upper guide roller, a lower guide roller, and a roller holder. The rolling mechanism is sandwiched by an upper rolling surface and a lower rolling surface of the rail. The guide structure is configured such that when an occupant load is input to the cushion frame, the guide roller and the rolling surface at one of a first contact point or a second contact point come relatively close together, such that pressure increases, due to a relative position of the roller holder and the rail changing, with the other of the first contact point or the second contact point as a reference point.
US10106057B2 Seat for motor vehicle and motor vehicle comprising such a seat
A seat having a fixed section, a movable section mounted so as to slide on the fixed section, a seating portion supported by the movable section, and a backrest mounted so as to rotate relative to the movable section to allow folding the backrest forward. The movable section is controlled to move rearward when the backrest is folded forward.
US10106056B2 Seat position-sensing system
An occupant support for a vehicle includes a vehicle seat and a foundation. The vehicle seat is configured to support an occupant of the vehicle above a floor of the vehicle. The foundation is configured to interconnect the vehicle seat to the floor to permit movement of the vehicle seat relative to the floor along a linear path.
US10106052B2 System and corresponding method for controlling the rotation speed of an electric motor of a motor vehicle
A system and method for controlling rotation speed of an electric motor of an electric or hybrid motor vehicle including a feedback-based regulator for regulating a torque setpoint using a control model, an input variable of the regulator being the torque setpoint as requested by a driver and the regulator using a pure delay.
US10106051B2 State diagnostic apparatus of fuel cell stack
An apparatus for diagnosing a state of a fuel cell stack is provided. The apparatus may diagnose the state of the fuel cell stack without including the DC-DC converter which boosts the DC voltage and the inverter which converts the boosted DC voltage into the AC voltage. In particular, the apparatus may diagnose the state of the fuel cell by applying the rectangular wave of the single frequency having a duty ration of about 0.5 to the fuel cell stack, measuring the voltage of the fuel cell stack, detecting the even multiple harmonic component of the frequency of the rectangular wave by performing the frequency conversion on the measured voltage, and then diagnosing the state of the fuel cell stack based on the magnitude of the detected harmonic component.
US10106050B2 Power supply device for an electrically operable vehicle and charging method
The disclosure relates to a power supply device for an electrically operable vehicle having an electric drive motor. The power supply device comprises an electric energy accumulator device, a range-extender with an internal combustion engine and a generator producing alternating current. The generator is mechanically connectable to the internal combustion engine, and the energy accumulator device is configured to be charged during driving with the alternating current from the generator. The energy accumulator device comprises several power supply connections on which respectively one of several controllable potentials can be provided, and several power supply branches having several serially connected power cell modules. Several power supply branches are interconnected on one end to the neutral point and each power supply connection is connectable to one end of a power supply branch.
US10106044B2 Charger having forced stop execution circuit to provide protection to a protection target
First and second detectors and first and second forced stop circuits are included in a charger including an AC/DC converter having a PFC circuit that converts AC power supplied from an external AC power supply into DC power and a smoothing capacitor, and a DC/DC converter that transforms power output by the AC/DC converter and supplies the transformed power to a vehicle-mounted battery. The first and second detectors detect voltage applied to the vehicle-mounted battery. The first forced stopper determines whether or not voltage detected by the first detector exceeds a predetermined threshold, and causes the DC/DC converter to stop when the predetermined threshold is exceeded. The second forced stopper determines whether or not voltage detected by the second detector exceeds the threshold, and causes the DC/DC converter to stop when the threshold is exceeded.
US10106041B2 Electrical or electronic device with two supply voltages
An electrical or electronic device (7) capable of being supplied with two different values of voltage from respectively a first electrical network (3) and from a second electrical network (8), comprises: a first connecting interface (70) capable of being linked, under normal connection conditions, with a ground conductor (GND_12) and a voltage conductor of the first electrical network (3); a second connecting interface (71) capable of being linked, under normal connection conditions, with the ground conductor (GND_48) and a voltage conductor of the second electrical network (8); the ground connections of the two connecting interfaces (70, 71) being linked together to form a common ground; and at least one switch module (74; 75) interposed in series on the common ground, the switch module being capable of switching into an open position following a modification in the connection conditions of the first or second interface.
US10106036B2 Protecting a power supply including a plurality of batteries in parallel against an external short-circuit
An electrical apparatus, including: a circuit breaker having a breaking capacity and a breaking current; a DC voltage source including two batteries connected in parallel, connected in series with the circuit breaker, the sum of short-circuit currents of the batteries being greater than the breaking capacity, each battery including: a first branch including storage batteries and a switch connected in series; a second branch connected in parallel with the first branch and including a free-wheeling diode; an ammeter measuring output current; and a control circuit configured to detect a short-circuit. The control circuits simultaneously keep a majority of switches open and close one switch to apply a current passing through the circuit breaker which is higher than the breaking current and lower than the breaking capacity.
US10106030B2 Arrangement structure of canister in vehicle
In a vehicle in which a muffler are arranged below a rear floor panel configuring a floor of a rear portion of a vehicle interior and on a further rear side than rear wheels in a vehicle forward/backward direction, and a battery for auxiliary machines is arranged on the further rear side than the rear wheels in the vehicle forward/backward direction and is housed in a battery housing recessed portion, a canister is arranged between the muffler and the battery for auxiliary machines in a vehicle width direction.
US10106027B1 Generator/cooling assembly and system for utility vehicle
A compact generator and coolant pump assembly may be used on a vehicle having a fluid reservoir and a plurality of electrical components disposed on the vehicle. The generator includes a rotor and stator disposed in a housing and the rotor is driven by a rotatable input member to generate an electrical output for use by one or more components of the vehicle. The assembly also includes a circulating pump connected to the generator housing and driven by the rotatable input member. The circulating pump may be connected to a fluid reservoir and to one or more electrical components such as a controller or battery on the vehicle through a set of coolant lines to provide coolant to the electrical components. The circulating pump may be offset from the generator housing by a plurality of spacers.
US10106026B2 User interface for an electrically motorized vehicle
A system, method, and device for operations of an electrically motorized vehicle. The vehicle can utilize an electrically motorized wheel to convert a non-motorized wheeled vehicle to an electrically motorized wheeled vehicle. A user interface for controlling the device of the electrically motorized wheel includes at least one button displayable by the user interface to control a function associated with the device.
US10106021B2 Arrangement comprising a cover for a vehicle roof
Vehicle roof arrangement can have displaceable sliding member, activation element having a mechanical coupling element, locationally fixed construction element in relation to the guide rail and has a coupling element pocket, and an elastic element mounted to be locationally fixed in relation to the guide rail. In a first state the elastic element protrudes into the pocket. In a second state the elastic element is guided out of the pocket. In a first movement section of the sliding member the elastic element by the sliding member is transferable from the first state to the second state. In an adjacent second movement section an introduction of the coupling element into the pocket is controllable, and the activation element is blocked in the longitudinal direction of the vehicle. In an adjacent third movement section the elastic element is again transferable to the first state, and the coupling element is blocked.
US10106015B2 Air filter for a ventilation device of a motor vehicle and method for the installation thereof
An air filter for a ventilation device of a motor vehicle is disclosed. The air filter has a frame element holding a filter element which can be connected to a receiving shaft of the ventilation device by at least one plug opening to form a plug connection with a guiding element. The frame element has at least one preparation for the production of the plug opening. A method for the installation of such an air filter is also disclosed.
US10106013B2 Heat exchanger arrangement
A heat exchanger assembly for a vehicle heating device includes inner heat exchanger housing (12) and outer heat exchanger housing (14). A fluid flow space (24) is formed between the inner heat exchanger housing and the outer heat exchanger housing. Flow guiding formations (40, 42), along circumferential walls (18, 22) of the housings, divide a portion of the fluid flow space into a first partial flow space (44) and a second partial flow space (46). A fluid inlet opening (49) opens to the first partial flow space and at least one fluid outlet opening (51) opens to the second partial flow space (46). A press fit formation (94) fixes the inner heat exchanger housing in relation to the outer heat exchanger housing and includes the first flow guiding formation and the second flow guiding formation and/or the press fit formation is in an end region (32) of the circumferential walls.
US10106012B2 Air-conditioner for vehicle
An air-conditioner for a vehicle includes: a first circuit in which a cooling medium circulates; a heater heating the cooling medium; a first pump disposed in the first circuit; a second circuit cooling a heat emitting portion; a second pump disposed in the second circuit; an adjustment portion controlling a circulation amount of the cooling medium flowing in the first circuit and a circulation amount of the cooling medium flowing in the second circuit; and a control portion. The vehicle includes a regenerative device, and a storage device is charged with electric energy recovered by the regenerative device. When the regenerative device is recovering the electric energy and when it is determined that power in the storage device needs to be consumed, the control portion drives the heater to heat the cooling medium such that the power in the storage device is converted into heat energy.
US10106010B2 Modular torque compensated walking beam assembly for work vehicle
A walking beam assembly includes a support beam and a mount member configured to mount the support beam on a vehicle chassis. Furthermore, the assembly includes a gear assembly that is supported proximate an end of the support beam. The gear assembly includes a gear train and a gear housing. The gear train is operably coupled to a wheel hub. The gear housing substantially encloses the gear train. Moreover, the walking beam assembly includes an input drive assembly with at least one movable part configured to deliver an input torque from the vehicle engine to the gear train. The input drive assembly includes an input drive housing that substantially encloses the at least one movable part. The input drive housing is attached to the gear housing such that an interior of the input drive housing is in fluid communication an interior of the gear housing.
US10106005B2 Carrier device capable of varying contact damping with pressured displacement
The present invention provides one or more carrier devices capable of varying contact damping with pressured displacement. The device is configured to be installed on mechanical force-receiving structures that have rolling wheels, rolling balls or slidably displaceable terminal block structure, carrying devices and transportation devices for humans or objects. When receiving pressure smaller than a set value, the device provides low contact damping and is thus easy to move. On the other hand, when receiving pressure greater than the set value, it provides high contact damping so as to prevent slip and thereby ensure safe placement. In addition, when receiving pressure smaller than the set value, the device has its pre-stressed structure generate modulation to displacement corresponding to the size of the pressure it receives for the purpose of shock absorbency.
US10106003B2 Trailer hitch
A ball-type hitch half is mounted on a towing vehicle, and a socket is mounted on a pivotable arm attached to the towed vehicle. The socket includes a shoulder surrounding the socket including a plurality of radially spaced pins. The ball has a neck that extends downward. Surrounding the neck is a peripheral collar on which a plurality of arcuately extending electrical contacts are provided. The pins surrounding the socket on its peripheral shoulder are spring biased in the downward direction such that they are forced into engagement with the arcuate contacts on the collar which is spring biased upward. When the socket is installed and locked over the ball, the contact pins are spring biased into contact with the arcuate electrical contact areas such that for any rotative or pivoted position of the towed vehicle with respect to the towing vehicle, the pins maintain contact with the arcuate contacts.
US10105993B2 Pneumatic tire
A pneumatic tire 1 has a tread portion 2 provided in a shoulder land region 5 with: axially inner shoulder sipes 8 each extending axially outwardly from a shoulder main groove 3 to its axially outer end 8e terminated within the shoulder land region 5; and axially outer shoulder sipes 9 each extending axially outwardly from its axially inner end 9i located axially outside the axially outer end 8e. The axially inner end 9i of each axially outer shoulder sipe 9 is positioned on an axially outward extension of one of the axially inner shoulder sipes 8.
US10105984B2 Electronic device for erasing contents on a writing board and a method thereof
The present disclosure relates to an electronic device for erasing contents on a writing board. The electronic device comprises a motion detecting unit for detecting movement of the electronic device from resting position which then transmits an activation signal to activate a processing unit and a proximity sensor. The proximity sensor identifies proximity of the electronic device with the writing board. The processing unit receives a signal from the proximity sensor when the electronic device is proximal to the writing board. Further, the processing unit receives selection of colours through user interface on the electronic device for identifying erasable or retainable contents on the writing board. The processing unit transmits a control signal to motion control system to control moveable cleaning surface of the electronic device to perform either pulling or pushing the moveable cleaning surface backward or forward respectively based on the selection of colours.
US10105982B2 Security element having a lenticular image
A security element for securing security papers, value documents and other data carriers, has a lenticular image that, from different viewing directions, displays at least two appearances. The lenticular image includes a lens grid composed of a plurality of microlenses and a laser-sensitive motif layer arranged spaced apart from the lens grid. The laser-sensitive motif layer comprises, in two or more motif layer sub-regions, different markings introduced by the action of laser radiation and that, when the motif layer is viewed with the lens grid, produce at least two appearances. The lens grid is divided into two or more lens grid sub-regions in which the microlenses each comprise differently refractive lens surface forms. The different lens grid sub-regions are congruent with the different motif layer sub-regions, and the markings of the motif layer sub-regions being produced by laser impingement of the lens grid sub-regions.
US10105981B2 Transfer lamination
In a transfer printing method using a transfer layer on a carrier layer, an image is printed over a transfer section of the transfer layer using a thermal print head and a print ribbon. At least one non-transfer portion of the transfer section is heated using the thermal print head without bonding the at least one non-transfer portion of the transfer section to the print ribbon. The at least one non-transfer portions of the transfer section are transferred from the carrier layer to an adhesive panel of the print ribbon using the thermal print head. Imaged transfer portions of the transfer section remain adhered to the carrier layer. The imaged transfer portions of the transfer section are then transferred from the carrier layer to a substrate using a transfer device.
US10105975B2 System and method for printing scratch-off lottery tickets
A method for producing scratch-off lottery tickets in a high speed printing line is provided, wherein the printing line includes one or more inkjet printing machines that print lottery tickets on a continuously running paper stock. One or more primer layers are applied to a surface of the paper stock in a defined game play area on each lottery ticket. With the inkjet printing machines game play indicia is printed over the primer layers in the game play area on each lottery ticket at a resolution of at least 600 dpi. The running paper stock is conveyed through the inkjet printing machines at a rate of at least 950 ft./min. The ink jet printing machines use a specially formulated dye-based ink.
US10105971B1 Platen rib protector
A platen protector for a printer device has a protector blanket to cover a printer platen of the printer device to prevent from causing scratches on print media by the printer platen. The platen protector has a fixing system to fixate the platen protector relative to the printer platen. The protector blanket is porous to pass through vacuum applied by the printer platen to attract print media.
US10105969B2 Elastic roller
An elastic roller includes an inner layer side elastic member around a roller shaft, and a coating layer surrounding around the inner layer side elastic member, the coating layer contacting a belt-shaped member. The coating layer is made of silicone resin having JIS-C hardness of 20 degrees or less. A base layer and an intermediate layer of the inner layer side elastic member have JIS-A hardness of 30 to 80 degrees. The rubber hardness of the base layer is higher than the rubber hardness of the intermediate layer. The intermediate layer has tearing strength of 25 N/mm or more, the tearing strength being measured using an unnicked angle-shaped test piece in accordance with JIS K 6252. The intermediate layer has internal grooves having a groove angle of 40 to 160 degrees and having a V-shaped cross section.
US10105965B2 Ink jet printing method and ink jet printing apparatus
An ink jet printing method includes attaching an ink composition to a cloth by using a printer head which has a nozzle discharging the ink composition, a pressure chamber for imparting pressure to the ink composition to cause the nozzle to discharge the ink composition, and a connection portion connecting the pressure chamber and the nozzle, and in which a distance of the connection portion is 500 μm or more, the distance of the connection portion being from a portion of the pressure chamber where the ink flows out from a pressure chamber to the nozzle side to the nozzle, in which the ink composition includes the resin as a solid content in the amount of 10% by mass to 26% by mass with respect to the ink composition, the ratio of the total content of the organic solvent to the total content of the solid content of the resin is 0.3 or more, and a sum of the total content of the solid content of the resin and the total content of the organic solvent is 37% by mass or less with respect to the ink composition.
US10105964B2 Flatbed printer assembly and a method therefor
A flatbed printer assembly includes a controller for controlling the movements of a gantry, a carriage support and the print head while moving over a medium support table. The controller is configured to receive a print job including a cut path intended to circumvent a piece of the recording medium, a first image intended to be printed on a front side of the piece of the recording medium, a second image intended to be printed on a back side of the piece of the recording medium, wherein at least one of the first and second image is intended to be printed at least partially in a full bleed print mode. Shapes are selected for a first alignment mark for the first image and a second alignment mark for the second image. A first location is determined on the front side of the recording medium according to the selected shape of the first alignment mark. The first location crosses the cut path. A second location on the back side of the recording medium is determined according to the selected shape of the second alignment mark. The second location crosses the cut path. A first sub-image is extracted from the first image which is intended to be printed on the first location of the first alignment mark. A second sub-image is extracted from the second image which is intended to be printed on the second location of the second alignment mark. The first sub-image is printed at the first location as being the first alignment mark. After the recording medium is turned upside down on the medium support table, the second sub-image is printed at the second location as being the second alignment mark.
US10105963B2 Region-of-interest based print quality optimization
A method for printing includes analyzing print quality requirements for a printing area; adjusting settings for heater elements (e.g., energy and/or firing durations) of strobe lines based on the requirements analysis; and providing a plurality of individual strobe signals to the strobe lines. The strobe signals can be transmitted simultaneously, for example with a field-programmable gate array. Analyzing print quality requirements can include separating the printing area into one or more areas of interest, such as rows and/or columns. For each area of interest individual print quality settings (e.g., darkness, contrast, and/or media sensitivity) may be selected.
US10105960B2 Set of tank and bottle, and bottle
There is provided a set of tank and bottle. A tank includes a liquid chamber, an inclined wall and an inlet. A bottle includes a bottle body having a first opening, and a nozzle. The nozzle has: a trunk section fitted onto the end portion of the bottle body; a shoulder section brought into contact with the end portion of the bottle body; and a nozzle section having a second opening formed in a protruded end portion thereof. In a pouring posture of the bottle in which the nozzle section inserted into the inlet is positioned at a periphery of the inlet, an angle defined between a normal line of the inclined wall and an inner surface of the nozzle section is smaller than an angle defined between the normal line and a horizontal line.
US10105959B2 Liquid supplying apparatus, liquid ejecting apparatus, and liquid container unit
A liquid supplying apparatus, configured to supply a liquid to a liquid ejecting section that is configured to eject the liquid, includes a tank configured to contain the liquid, the tank including a liquid containing section, and a container section connected to the tank. The container section is exposed to air through the tank, and the container section is connected to the liquid containing section of the tank.
US10105956B2 Liquid consumption apparatus, liquid consumption system
A printing apparatus 10 calculates an consumed ink amount which is a consumed amount of ink ejected from an ejection unit that ejects ink supplied from an ink cartridge 60, and, in the case where an unused ink cartridge 60 is installed, executes initial maintenance of the ejection unit, determines an initial consumed ink amount which is a consumed amount of liquid consumed by the initial maintenance, writes the consumed ink amount and the initial consumed ink amount to a storage device 70 of the ink cartridge 60 as a consumed ink amount 73 and an initial consumed ink amount 75, and generates and notifies a ratio of the difference between the contained ink amount 71 and the consumed ink amount that is updated relative to the difference between the contained ink amount 71 and the initial consumed ink amount 75 as notification-use information.
US10105953B2 Cleaning device of liquid ejection head and liquid ejection device
A cleaning device includes a blade unit configured to move relative to an ink jet head and to wipe an ejection surface of the ink jet head. The blade unit includes a first blade and a second blade that are arranged in a moving direction of the blade unit and formed into flexible plate shapes and a blower that makes an inner space, which is defined by the first blade and the second blade, into a negative pressure.
US10105952B2 Method for manufacturing liquid ejecting head and liquid ejecting head
Provided is a method for manufacturing a liquid ejecting head which includes a plurality of chips, each of which includes a plurality of segments, each segment including a pressure generating chamber communicating with a nozzle opening through which liquid is discharged, a diaphragm which is a portion of the pressure generating chamber, and a pressure generating unit causing a pressure change in the pressure generating chamber through the diaphragm, the method including measuring natural frequencies of the plurality of segments included in each of the chips, classifying the chips into ranks using the maximum value of the natural frequencies of the chips as a reference, and manufacturing the liquid ejecting head which includes the chips selected based on the ranks.
US10105950B2 Control apparatus and control method
A control apparatus includes an application unit, a conveyance unit, a stacking member, a pressing member, and a control unit. The application unit applies a recording agent to a recording medium, which then is conveyed by the conveyance unit. The stacking member stacks sequentially conveyed recording media with a surface of the recording media to which the recording agent is applied facing up. The pressing member presses the sequentially stacked recording media. The control unit controls timing at which the pressing member contacts the recording media. The pressing member presses an upper surface of the stacked recording medium. The control unit controls the timing at which the pressing member contacts a recording medium when the recording medium has been stacked on the uppermost recording medium, based on data for applying the recording agent to a predetermined area, on the recording medium, including an area which the pressing member can contact.
US10105947B2 Controlling advance of print media to deliver printing fluid from plural columns of nozzles
In some examples, a printing system includes a printhead comprising a nozzle array including plural columns of nozzles to deliver printing fluid to a print medium, wherein nozzles in a first column of the columns are offset from nozzles in a second column of the columns. A controller is to control printing onto the print medium using the printhead by, for each respective pass of a plurality of passes of the printhead over the print medium, controlling an advance of the print medium for a print mask pattern that controls firing of the nozzles of the printhead, where the controlled advance of the print medium causes nozzles from different columns of nozzles of the nozzle array to deliver dots of printing fluid to a given row of a swath in successive passes of the plurality of passes.
US10105940B2 Formation of composite laminates having one or more divergent flanges
Systems and methods are provided for divergent laminates. A method comprises providing a layup tool having a first upper face and a second upper face that rise to intersect each other at a ridge line, the layup tool further having a protrusion on top of a portion of the ridge line, and laying up a laminate onto the upper faces and the protrusion. The method also comprises placing a cure tool on top of the layup tool, the cure tool having a lower face that is dimensioned to mate with the upper faces along a portion of the ridge line that is not covered by the protrusion, thereby leaving a divergent flange of the laminate on top of the protrusion exposed, and sweeping the divergent flange of the laminate upward from the layup tool onto a vertical side the cure tool.
US10105934B2 Use of plasticizer-free polyvinylacetal for laminating sheets of polycarbonate
At least one polycarbonate sheet is laminated to at least one further rigid layer by at least one adhesion layer, characterized in that the adhesive layer consists of polyvinyl acetal having a content of vinylacetate groups of more than 10 wt. % but less than 25 wt. % and a content of plasticizer of less than 10 wt. %.
US10105927B1 Silicone-free thermoplastic elastomer (TPE) materials for use in carrier devices
The invention relates generally to carrier materials. More specifically, the present invention relates to silicon-free thermoplastic elastomer (TPE) materials for use in carrier devices. In some embodiments, a textured film to temporarily immobilize a device is provided, characterized in that a surface of the film in contact with the one or more objects is comprised of textured topology.
US10105926B2 Structural adhesive assemblies
A device and method for reinforcing, baffling or sealing a vehicle structure, comprising the steps of providing a flexible carrier and plurality of parallel strips located on opposing surfaces of the carrier.
US10105919B2 Method for manufacturing thin polarizer, and thin polarizer manufactured using same
The present invention relates to a method for manufacturing a thin polarizer, the method including: a step of preparing an unstretched polyvinyl alcohol-based film having a thickness of 20 μm or less, in which a strength applied to stretch the film by 6 times is 4 N or more; and a single stretching step of forming a stretched polyvinyl alcohol-based film having a thickness of 10 μm or less by stretching the unstretched polyvinyl alcohol-based film solely, and a thin polarizer manufactured by using the same.
US10105914B2 Gear and manufacturing method thereof
In a manufacturing method, an annular preform made of reinforcing fibers is set in a region of a mold which corresponds to a sleeve. In this state, this region of the mold and a region of the mold which corresponds to a tooth portion are filled with a resin. A gear is manufactured by this process.
US10105907B2 Method of printing an object having a surface of varying height
A printing system and method of printing an object having a surface of varying height, by a printer configured to print a number of pass images on top of each other in a number of passes, including: deriving from an object image a number of pass images to be printed on top of each other, including: establishing pass pixels of the pass images for which pass pixels a pass pixel height is defined, where a sum of the defined heights of a sequence of pass pixels that corresponds to a respective pixel of the object image equals the height of that pixel of the object image; and printing the pass images on top of each other. An amount of printed material that is printed per printed pass pixel is varied in accordance with the defined pass pixel heights. The pass pixels heights are selected, based on random data, from a respective set of at least two positive pass pixel heights.
US10105905B1 Using triangular tessellation in 3D printing
Systems, methods, and computer readable media to improve the operation of three dimensional (3D) printer systems are described. In general, techniques are disclosed for providing improved (smaller) print times and reduced consumption of material for a given end assembly. More particularly, a print-head motion exhibiting a triangular support pattern (aka triangular tessellation) is shown to be more efficient than circular print head motions used in current 3D printers in terms of speed and/or material usage.
US10105904B2 Device and method for supporting 3D object printing and apparatus for providing 3D object printing service
Disclosed herein is a device and method for supporting 3D object printing and an apparatus for providing a 3D object printing service. A proposed device for supporting 3D object printing includes an information collection unit for collecting preference information of a user and performance information of a 3D printer. A download unit downloads a 3D model that is an object to be printed and model information defined in the 3D model in response to a printable selection signal. A model information creation unit creates new model information based on the 3D model and the model information defined in the 3D model. A print control command generation unit generates a print control command based on the preference information of the user and the performance information of the 3D printer, output from the information collection unit, and the new model information, output from the model information creation unit.
US10105899B2 IV membrane attachment systems and methods
An intravenous delivery system may have a liquid source containing a liquid, tubing, and an anti-run-dry membrane positioned such that the liquid, flowing form the liquid source to the tubing, passes through the anti-run-dry membrane. The anti-run-dry membrane may be positioned within an exterior wall of a drip unit, and may have a weld surface secured to a seat of the exterior wall via application of compression to press the weld surface against the seat, and application of coherent light or vibration. In response to application of the coherent light or vibration, localized melting may occur, causing the weld surface to adhere to the seat. The anti-run-dry membrane may be modified to have a melting point close to that of the seat. Ultrasonic or laser welding may be applied in a manner that causes portions of the seat to melt and flow into pores of the weld surface.
US10105895B2 Apparatus for additively manufacturing of three-dimensional objects
An apparatus (1) for additive manufacturing of three-dimensional objects (2) by successive, selective layer-by-layer exposure and thus solidification of construction material layers of a construction material (3) that can be solidified by an energy beam (5) generated by an energy beam generation device (4).
US10105888B2 Injection molding machine with ejector and ejector operating method for injection molding machine
An acceleration distance for acceleration at a set acceleration rate, required for an ejection start position passing speed in an ejection start position, is obtained, and a position behind the ejection start position by the acceleration distance is set as an advance start position of an ejector. Thus, an ejector plate can start to move at an optimal speed.
US10105887B2 Plasticizing unit of an injection molding machine for micro-injection molding
A plasticizing unit of an injection molding machine for micro-injection molding includes a plasticizing cylinder and a screw, which conveys material to be plasticized from a feed opening in the direction of an outlet opening. At least one longitudinal section of the plasticizing cylinder between the feed opening and the outlet opening is formed as a transition region in which the inner diameter of the plasticizing cylinder tapers in the direction of the outlet opening to the outer diameter of the screw. The transition region is formed by a sleeve-shaped transition element which is removably and replaceably mounted within the plasticizing cylinder. The plasticizing cylinder is designed as at least two parts for removing and replacing the sleeve-shaped transition element.
US10105883B2 Imprint lithography system and method for manufacturing
A nanoimprint lithography system and method for manufacturing substrates with nano-scale patterns, having a process chamber with transparent sections on both top and side walls, a robot for automatic molds and substrates loading and unloading, and optical and stage apparatuses to obtain the desired spatial relationship between the mold and substrate, with an enclosed volume referring to mold mini-chamber being formed between the mold/holder and top wall of the chamber and with the process chamber and mini-chamber being capable of both vacuuming and pressurizing, and inside the chamber, a ring shape seal assembly is installed and a mold support assembly can be installed that aids in imprinting all the way to the edge of the substrate with various embodiments for carrying out fluid pressure imprinting, separation, measurement and control of mold and substrate gap, substrate thickness, and system axial force.
US10105880B2 Process for preparing thermally conductive oriented UHMWPE products and products obtained therefrom
The present disclosure relates to a process for preparing of high thermal conductivity and high heat capacity oriented ultrahigh molecular weight polyethylene (UHMWPE) product. The process includes feeding UHMWPE through rollers to obtain a pre-laminate which is further hot stretched to obtain the oriented UHMWPE product having high thermal conductivity and high heat capacity. The temperature of stretching is maintained below the melt temperature of the UHMWPE throughout the entire process. There is also provided a high thermal conductivity and high heat capacity oriented UHMWPE product prepared by the process of the present disclosure. The oriented UHMWPE product is characterized in the axial thermal conductivity in the range of 70 to 200 W/mK, transverse direction thermal conductivity in the range of 0.022 to 0.045 W/mK and heat capacity in the range of 6 to 25 MJ/m3K.
US10105877B2 Multilayer riblet applique and methods of producing the same
Multilayer riblet applique and methods of producing the same are described herein. One disclosed example method includes applying a first high elongation polymer material to a web tool, where the web tool is to be provided from a first roll, and heating, via a first heating process, the first high elongation polymer material. The disclosed example method also includes applying a second high elongation polymer material to the first high elongation polymer material, and heating, via a second heating process, the second high elongation polymer material. The disclosed example method also includes applying, via a laminating roller, a support layer to the second high elongation polymer material.
US10105876B2 Apparatus for generating and dispensing a powdered release agent
An apparatus 20 and a method 100 for generating and dispensing a powdered 60 release agent during an additive manufacturing build is disclosed. A solid body 28 of release agent material is ground insitu by a grinder 50 and dispensed on a surface of the part 72 to prevent adhesion of an adjacent layer of a base material 70. With the addition of the powdered 60 release agent, a support structure 76 is easily separated from the base material 70 when the part 72 is complete, saving time and preventing the part 72 from sustaining unintentional damage. Since no powdered 60 release agent is actually loaded or stored in the apparatus 20, the potential for spillage, waste, inconsistent dispensing, inadvertent dispensing, and clumping due to humidity is eliminated.
US10105866B2 Method for preparing functional engineered wood
The present invention relates to furniture panels, and more particularly, to a method for preparing functional engineered wood. It includes the following steps: make veneer blanks by rotary cutting or splicing, and cut the veneer blanks into desired dimensions to obtain veneers A. Soak the veneers A in a ternary mixed solution of a biomass nanocellulose solubilizer, a fire retardant and an acid dye for toughening, fire retardation and dyeing to obtain veneers B. Add a formaldehyde decomposing powder into a modified MUF adhesive, mix them up, coat the veneers B with the mixture to obtain veneers C. Assemble and cold-press the veneers C to obtain flitches D, and saw the flitches D into desired patterns and dimensions to obtain finished products.
US10105865B2 Crown molding jig device and related devices
A crown molding jig device may include first and second frames. Each of the first and second frames may have a vertex portion, and first and second legs extending from the vertex portion. The second legs of the first and second frames may define a recess between. The first leg of the second frame may define first and second slots. The crown molding jig device may include first and second adjustable studs carried by the first leg of the first frame, and being slidably received by the first and second slots so that the recess is adjustable in size.
US10105864B2 Food processor with a lockable adjustable blade assembly
A food processor includes a bowl with a removable lid. Food items are advanced into the bowl through a feed tube formed in the lid where they are cut by a blade assembly. A rotating disk is adjustable relative to the blade assembly to vary the thickness of the food items cut by the blade assembly. A user-operated pin is positioned below the rotating disk and is moveable between a first position in which the rotating disk is prevented from moving upwardly and downwardly, and a second position in which the rotating disk is permitted to move upwardly and downwardly.
US10105858B2 Shaving device
A shaving device comprising a head assembly including a support member having at least one support member magnet and a blade cartridge having at least one face with at least one razor blade and configured to be rotatably coupled to the support member about a pivot axis. The blade cartridge includes at least one blade cartridge magnet having a pole aligned with a pole of the support member magnet to generate a magnetic force that urges the blade cartridge about the pivot axis towards an initial starting position (ISP), wherein the blade cartridge is further configured to rotate about the pivot axis away from the ISP upon application of an external force sufficient to overcome the magnetic force between the support member magnet and the blade cartridge magnet.
US10105856B2 Hair clipping device
A hair clipping device includes a housing, and a cutting assembly which is arranged on a distal end of the housing and which includes a stationary cutting blade and a moveable cutting blade. The hair clipping device includes further includes a comb attachment which is releasably attachable to the housing and includes a plurality of comb teeth. A front side of the housing that runs transverse to the distal end and the cutting assembly includes a corrugated surface with a plurality of adjacent ribs and recesses running parallel to each other. The backside of the comb teeth contacts the corrugated surface when the comb attachment is attached to the housing.
US10105852B2 Transport tool for transporting a laboratory article
A transport tool for transporting a laboratory article using a pipette of a pipetting system includes at least one plug-in sleeve, which is implemented for the releasable plugging-in of a receptacle cone of a pipette, and which can be plugged onto the receptacle cone of the pipette instead of a disposable pipette tip. In addition, the transport tool includes an article holder having at least one holding part, which is implemented to form a support connection with a laboratory article. A connecting part connects the article holder to the plug-in sleeve, so that holding axes of the article holder and the sleeve axis of the plug-in sleeve are arranged coaxially or axially-parallel to one another.
US10105850B2 Natural pitch and roll
A control system may receive a first plurality of measurements indicative of respective joint angles corresponding to a plurality of sensors connected to a robot. The robot may include a body and a plurality of jointed limbs connected to the body associated with respective properties. The control system may also receive a body orientation measurement indicative of an orientation of the body of the robot. The control system may further determine a relationship between the first plurality of measurements and the body orientation measurement based on the properties associated with the jointed limbs of the robot. Additionally, the control system may estimate an aggregate orientation of the robot based on the first plurality of measurements, the body orientation measurement, and the determined relationship. Further, the control system may provide instructions to control at least one jointed limb of the robot based on the estimated aggregate orientation of the robot.
US10105848B2 Machine that stops movement of member on drive axis due to abnormality in brake
A robot includes a motor that includes a brake and moves an arm on a drive axis, and a rotational position detector that detects movement of the arm. When a state occurs in which the robot is preferably emergency-stopped, a control device performs an emergency stop control in which the brake is operated and power supply to the motor is interrupted. When the movement of the arm is detected based on an output of the rotational position detector during the emergency stop control, the control device supplies power to the motor to prevent the movement of the arm.
US10105841B1 Apparatus and methods for programming and training of robotic devices
Apparatus and methods for training and operating of robotic devices. Robotic controller may comprise a plurality of predictor apparatus configured to generate motor control output. One predictor may be operable in accordance with a pre-configured process; another predictor may be operable in accordance with a learning process configured based on a teaching signal. An adaptive combiner component may be configured to determine a combined control output controller block may provide control output that may be combined with the predicted control output. The pre-programmed predictor may be configured to operate a robot to perform a task. Based on detection of a context, the controller may adaptively switch to use control output of the learning process to perform the given or another task. User feedback may be utilized during learning.
US10105840B2 Robot system including plurality of controllers connected via network
A robot system enabling a single teaching console to be used to easily teach a plurality of robots. The robot system includes a plurality of robot controllers connected through a network and a single teaching console. The teaching console is configured to be able to selectively communicate with any one of the robot controllers. The robot controller is configured so as to send a connect request to the teaching console when it is judged that the state of the robot has been switched to the teaching phase or maintenance phase. The teaching console is configured to respond to a connect request from the robot controller and switch destinations to enable communication with the robot controller.
US10105839B2 Electrolaminate clutches for an exosuit system
A flexible exosuit includes rigid and flexible elements configured to couple forces to a body of a wearer. Further, the flexible exosuit includes flexible linear actuators and clutched compliance elements to apply and/or modulate forces and/or compliances between segments of the body of the wearer. The flexible exosuit further includes electronic controllers, power sources and sensors. The flexible exosuit can be configured to apply forces to the body of the wearer to enable a variety of applications. In some examples, the flexible exosuit can be configured to augment the physical strength or endurance of the wearer. In some examples, the flexible exosuit can be configured to train the wearer to perform certain physical tasks. In some examples, the flexible exosuit can be configured to record physical activities of the wearer.
US10105838B2 Automatically travelling device and control method therefor
An automatic moving device and a control method therefor. The automatic moving device comprises a battery pack providing power. The automatic moving device can work within a working area and automatically return to a charging station for charging. The control method comprises monitoring the power level of the battery pack; if the power level of the battery pack is less than or equal to a preset power level, initiating an action of returning the automatic moving device to the charging station; and after a preset time period, stopping the travel. By setting a preset time period simultaneously with initiating a return action, and executing a return action within the preset time period, the control method prevents damage to the battery pack from over-discharging caused by the automatic moving device continually returning, thus achieving the effects of protecting the battery pack and extending the life thereof.
US10105837B2 Tracking enabled extended reach tool system and method
An extended-reach tool system may include a gimbal positioned adjacent a surface opening; an extended-reach arm having a tool and engaging the gimbal; a sensor system for measuring a position of the arm relative to the gimbal and a position and spatial orientation of the tool relative to the opening; a computer control that converts one or both of the rotational and linear measurements from the sensor system into spatial location representations for virtual representations of 3-D models of the workpiece and tool, determines a position and orientation of the tool relative to the opening and workpiece, and adjusts the virtual representations of the 3-D models of the workpiece and tool as the arm and tool move relative to the workpiece, representing a real-time orientation of the tool relative to the workpiece; and a display for displaying the virtual representations of the 3-D models of the workpiece and tool.
US10105835B1 Hand tool holding rack assembly
A hand tool holding rack assembly has multiple rail bases and two fixing bases. The rail bases are disposed to be parallel with each other, and each rail base has an elongated body and multiple positioning mounts. The positioning mounts are mounted slidably on the elongated body. The two fixing bases are connected with ends of the elongated bodies of the rail bases to connect the rail bases with each other, and each fixing base has at least one fixing slot, multiple fixing tabs, and multiple fixing fasteners. The at least one fixing slot is defined through the fixing base. The fixing tabs are attached respectively to the elongated bodies of the multiple rail bases, and each fixing tab has a threaded hole. The fixing fasteners are mounted through the at least one fixing slot and are screwed respectively with the threaded holes in the fixing tabs.
US10105831B2 Ratchet tool
A ratchet tool includes a cylindrical ratchet handle. The ratchet handle has an accommodation cavity therein. A multi-tool assembly is provided in the accommodation cavity and rotatable relative to the accommodation cavity. The present invention has a simple structure and is convenient for use. Multiple tools are provided to become one-piece. The entire contour is cylindrical, which is convenient for the user to hold the ratchet tool.
US10105830B2 Electronic click wrench
An electronic click wrench comprises a handle for applying torque through a shaft to a working head. The shaft includes torque sensing means for calculating the torque applied to a workpiece by the working head, and a trigger mechanism for sending a haptic feedback to a user by triggering a small movement of the handle relative to the working head when a set point torque is reached. The trigger mechanism comprises a permanent magnet that is normally anchored by magnetic attraction to a pole piece so as to resist separation when a force is applied through the handle, and an electromagnetic means actuable to reduce or cancel that magnetic attraction so as to permit separation of the pole piece and permanent magnet, thus generating the haptic feedback. Operation of the electromagnet may oppose the flux of the permanent magnet through the pole piece. Alternatively operation of the electromagnet may divert the flux of the permanent magnet away from the pole piece.
US10105829B2 Vacuum adapter for a power tool
A vacuum adapter for a power tool, with a bit holder extending from a front end of the power tool, is arranged to house the bit holder and to suck screws into alignment with a bit arranged inside the bit holder. The vacuum adapter includes: a connection part for connecting the vacuum adapter to the front end of the power tool such that the vacuum adapter covers the bit holder; a vacuum connection for connecting the vacuum adapter to a negative pressure source; a quick coupling for rapid disconnection of at least a part of the vacuum adapter in order to access the bit holder for exchanging bits; and a cover part arranged to cover the bit holder and that is connected to the connection part via a quick coupling and that may be separately disconnected from the power tool, leaving the connection part attached to the power tool.
US10105822B2 Holding device for a grinding means
A holding device, in particular a grinding disc, for a grinding member includes at least one support member that has at least one material opening configured for transverse transport of grinding dust to one side facing the grinding member in a plane parallel to a grinding surface. The holding device further includes at least one securing layer configured to secure the grinding member on the at least one support member. When decoupled from the grinding member, the at least one material opening is at least substantially open on a side facing the grinding member and on a side facing away from the grinding member is substantially delimited by the support member.
US10105819B2 Support and coupling assembly for a screw auger having multiple coupled screws
A support and coupling assembly for a moving screw auger that is used to move grit, such as grit that is used in the blast cleaning industry. The support and coupling assembly includes a hanger bearing assembly with a hanger bearing bracket with an end for engaging a support surface, such as a wall or a ceiling, and a removed end. A roller bearing engages the removed end of the hanger bracket and a shaft is press fit into the roller bearing. A pair of hub assemblies with flights engages the shaft and rotates with the shaft. Connector assemblies engage the hub assemblies to connect the hub assemblies to screw portions on either side of the hanger bearing assembly. The flights on the connector assemblies will cause the grit to speed up as it moves from the screw portion to the connector assembly.
US10105816B2 Device for detaching/attaching hand grinder polishing disk
The present invention relates to a device for detaching/attaching a hand grinder polishing disk, the device being clamped on the rotating shaft of a grinder main body so as to enable the easier and quicker detachment/attachment of a consumable polishing disk used for finishing, cutting, severing, etc. the surface of a target object, or to enable the definite prevention of loosening, vibration phenomenon, etc. The present invention comprises: a grinder main body which has a rotating shaft operating at a high speed by means of air pressure or the driving of an electric motor; a power transmission member which has a stopping protrusion formed on the upper end part of the body thereof and a hexagonal body including a flange formed on the center part of the body thereof, and which is clamped on the rotating shaft of the grinder main body by a fixing bolt; a stopper main body which has a hexagonal hole formed on the inner circumferential surface thereof for accommodating the power transmission member, and which has an arc-shaped seat groove formed on the circumference of the hexagonal hole so as to face each other; a pair of upper and lower rotating plates which are each fitted in a flat plate portion on the upper end of the stopper main body; and a disk holder which has an upper fixing ring and a lower support plate assembled on the power transmission member for fixing an abrasive material.
US10105812B2 Polishing pad configuration and polishing pad support
Chemical mechanical polishing can be used for “touch-up polishing” in which polishing is performed on a limited area of the front surface of the substrate. The contact area between the polishing pad and the substrate can be substantially smaller than the radius surface of the substrate. During polishing, the polishing pad can undergo an orbital motion. The polishing pad can be maintained in a fixed angular orientation during the orbital motion. The contact area can be arc-shaped. The contact area can be provided by one or more lower portions projecting downward from an upper portion of the polishing pad. A perimeter portion of the polishing pad can be vertically fixed to an annular member and a remainder of the polishing pad within the perimeter portion can be vertically free.
US10105811B2 Eddy current system having an elongated core for in-situ profile measurement
An eddy current monitoring system may include an elongated core. One or more coils may be coupled with the elongated core for producing an oscillating magnetic field that may couple with one or more conductive regions on a wafer. The core may be translated relative to the wafer to provide improved resolution while maintaining sufficient signal strength. An eddy current monitoring system may include a DC-coupled marginal oscillator for producing an oscillating magnetic field at a resonant frequency, where the resonant frequency may change as a result of changes to one or more conductive regions. Eddy current monitoring systems may be used to enable real-time profile control.
US10105810B2 Mechanochemical conditioning tool
A tool (1) for mechanochemical treatment comprises a shaft (10), a number n of working ledges (20), n≥1, and a force application arrangement (2). The force application arrangement (2) is configured for applying a working force (F) on the working ledges (20). The working ledges (20) comprises wear-resistant material with a Vickers number above 800 HV and a Young modulus above 200 GPa. Each working ledge (20) has a contact surface (22) facing away from a main axis (11) and having a surface roughness Ra below I μm. The contact surface (22) has a convex curvature which has a radius of curvature that is at most equal to a closest distance from that point to the main axis. A width of the contact surface (22) is less than r/2n. The working force applied on each working ledge (20) is at least P−L−r/2n, where P=107 Pa and L is the contact surface length.
US10105809B2 Device and method for measuring and monitoring tools
A device for measuring and monitoring tools of a machine tool, wherein the machine tool comprises a spindle shaft for the tool, the shaft being arranged in a spindle housing, wherein a work piece with good electric conductivity can be machined using the tool, wherein the spindle shaft is electrically insulated from the spindle housing, includes a measuring and monitoring system. The measuring and monitoring system measures at least one electric measurement, which depends on the contacting state between the tool and the work piece. A rotary transmitter contacts the rotating spindle shaft to measure the measurement detectable between the tool and the work piece, wherein the rotary transmitter is connected with the spindle housing in an electrically insulated manner.
US10105808B2 Processing system having function for maintaining processing accuracy
A processing system having a function for appropriately maintaining processing accuracy, without depending on a degree of abrasion of a tool. An unused tool used in a machine tool is captured by using a camera mounted on a robot, so as to obtain a reference image of the tool. Next, an image of the tool is captured after a predetermined number of processing operations carried out. An average amount of tool abrasion per one processing operation is calculated based on the two images, so as to estimate a current amount of tool abrasion. Based on the estimation result and a previously input limit amount of abrasion, the number of remaining possible processing operations of the tool is calculated and output.
US10105804B2 Fixture system and method for securing an airfoil during material removal operations
A method of removing material from an airfoil includes engaging a root of the airfoil within a root-securing fixture, engaging a tip of the airfoil within a tip-securing fixture, and removing material from the airfoil. The method further includes disengaging the tip of the airfoil from the tip-securing fixture to allow movement of the tip from a clamped state position to a free-state position. The method further includes reengaging the tip of the airfoil within the tip-securing fixture in the free-state position, and removing additional material from the airfoil.
US10105803B1 CNC fixture
A rotary head plate having a first precision surface and a second precision surface. The rotary head plate mounted to the first sub fixture. A second sub fixture being able to freely rotate with the rotary head plate when rotated. A tailstock plate mounted to the second sub fixture. The tailstock plate having a first precision surface and a second precision surface, A first head plate attached to the first precision surface of the rotary head plate and the first precision surface of the tailstock plate. A second head plate attached to the second precision surface of the rotary head plate and the second precision surface of the tailstock plate. The first head plate and second head plate adapted to each receive two cylinder heads. The first head plate and second head plate each including at least one cylinder head opening.
US10105796B2 Chromium free and low-chromium wear resistant alloys
Disclosed herein are embodiments of hardfacing/hardbanding materials, alloys, or powder compositions that can have low chromium content or be chromium free. In some embodiments, the alloys can contain transition metal borides and borocarbides with a particular metallic component weight percentage. The disclosed alloys can have high hardness and ASTM G65 performance, making them advantageous for hardfacing/hardbanding applications.
US10105794B2 Method of forming a lead-free solder composition
A method of forming a solder composition comprises mixing indium, nickel, copper, silver, antimony, zinc, and tin together to form an alloy that consists of about 4% to about 25% by weight tin, about 0.1% to about 8% by weight antimony, about 0.03% to about 4% by weight copper. about 0.03% to about 4% by weight nickel, about 0.03% to about 1.5% by weight zinc, about 66% to about 90% by weight indium, and about 0.5% to about 9% by weight silver. The solder composition formed by this method can be used to solder an electrical connector to an electrical contact surface on a glass component.
US10105783B2 Electrode diameter sensing consumables
The present disclosure provides a welding system capable of detecting a size of a welding material and automatically implementing appropriate arc starting parameters. The welding system includes a welder, a welding torch, and a sensor, in which the sensor is configured to detect the size of the welding material, directly or indirectly. The welder is automatically configured to produce an arc having the arc starting parameters determined from the size of the welding material detected by the sensor. The present disclosure decreases operational error by automatically changing arc starting parameters and/or welding parameters based upon a change in welding material size, rather than requiring an operator to manually change the arc starting parameters and/or welding parameters.
US10105782B2 Feedback from a welding torch of a welding system
A method includes displaying, on a display of a welding torch, a welding parameter in relation to a predetermined threshold range for the welding parameter, a target value for the welding parameter, or some combination thereof as a position of the welding torch changes, an orientation of the welding torch changes, a movement of the welding torch changes, or some combination thereof, to enable a welding operator to perform a welding operation with the welding parameter within the predetermined threshold range, at the target value, or some combination thereof. The welding parameter is associated with the position of the welding torch, the orientation of the welding torch, the movement of the welding torch, or some combination thereof.
US10105775B2 Cutting tip, cutting tool and gear edge cut-off device
A cutting tip, a cutting tool and a gear edge cut-off device have greater ease-of-use than the conventional art. The cutting tip has a shaft portion supported linearly movably and forwardly biased in a linearly moving direction, an angular base portion provided at a front end of the shaft portion and having a pair of skirt faces and a ridge portion that extends obliquely with respect to the linearly moving direction, a groove depressed near the ridge portion of the skirt face, a blade edge on the cutting blade, positioned on a border line between the ridge portion and the groove, a rake face provided on the cutting blade and positioned further toward the groove side than the blade edge, and a flank face positioned further toward the ridge portion side than the blade edge and jutting out in the forward direction as it retracts from the blade edge.
US10105761B2 Assembly for tightening and securing male and female parts fitted together
An assembly for tightening and securing includes a first male part and a second female part fitted together, which have complementary forms. The fitting includes at least one contact surface of the first part with the second part. The assembly also includes at least one annular means mounted on the periphery of one of the two parts. The annular means is connected in a translational manner to the part on which the annular means is mounted when the annular means abuts with the part on which the means is mounted, and arranged to interact with a peripheral surface of the complementary part during a rotation of the annular means in relation to the complementary part.
US10105758B2 Arrangement for coating a powder
An arrangement includes a processing chamber, a coating platform located in the processing chamber, and a coating device with a coating element located in the processing chamber for coating a metal or ceramic powder. The arrangement also has an exchanging device for exchanging at least one portion of the coating element with another portion of the same coating element or for exchanging the entire coating element with another coating element within the processing chamber when the processing chamber is closed. The exchanging device can include a multiple head, e.g., a pivoting head or revolving head, an exchanging station, and/or a moving device that allows a coating element portion that is to be exchanged to be moved or pushed away. A part of the coating element can also be rolled on a supply roller, and the coating element portion can be exchanged by unrolling the coating element from the supply roller.
US10105756B2 Steam-blocking cooling systems that help facilitate directional solidification
An example cooling system for a mold assembly includes a quench plate that defines one or more discharge ports and one or more recuperation ports. A fluid is circulated from the one or more discharge ports to the one or more recuperation ports to cool the mold assembly. A blocking ring is positioned on the quench plate and defines a central aperture for receiving a bottom of the mold assembly. An insulation enclosure having an interior for receiving the mold assembly is positioned on the blocking ring. The blocking ring prevents vapor generated by the fluid contacting the bottom of the mold assembly from migrating into the interior of the insulation enclosure.
US10105749B2 Forging die heating apparatuses and methods for use
A forging die heating or preheating apparatus comprises a burner head comprising a plurality of flame ports. The burner head is oriented to compliment an orientation of at least a region of a forging surface of a forging die and is configured to receive and combust a supply of an oxidizing gas and a supply of a fuel and produce flames at the flame ports. The plurality of flame ports are configured to impinge the flames onto the forging surface of the forging die to substantially uniformly heat at least the region of the forging surface of the forging die.
US10105747B2 Roller bearing cage with tangs
The invention relates to a roller bearing cage comprising: a first annular ring; a second annular ring; at least one retainer portion attaching the first annular ring to the second annular ring to form the first and second annular rings in a cylinder-type structure; and a plurality of resilient tangs on each of the first and second annular rings, each tang protruding from the circumference of the respective annular ring at an angle with respect to the plane of the respective annular ring and toward the other annular ring.
US10105746B1 Tube end sealing method
In a method for closing open ends of tubes, an open tube end is closed using spin-tubing methods known in the art. Following the tube end closing, a concavity is formed in the tube end in a tube end forming machine. The tube end is brazed with the tube end facing upright, so that the braze alloy pools in the concavity, strengthening the tube end.
US10105745B2 Method of manufacturing a metal vessel
The present invention relates to a method of manufacturing a metal vessel by way of stamping of vertical halves from a metal sheet, and in particular to a method comprising: stamping at least a first vessel half and a second vessel half from a metal sheet; adhering at least the first vessel half with the second vessel half forming a vessel, the vessel being a single piece article having an opening on one end for ingress and egress of a liquid or a gas and having a seam along two of the vessel vertical walls and along the bottom of the vessel where the first vessel half and the second vessel half make contact; and applying a top finish at the opening of the vessel allowing for a closure to be used to seal and selectively reseal the vessel.
US10105743B2 Radial press
A radial press is provided with a base structure, a pressing tool accommodated therein and a drive unit. The pressing tool comprises a number of base jaws which are arranged about a press axis and can be moved by the drive unit towards or away from the press axis in a synchronous manner and radially in relation to said press axis, and substantially wedge-shaped press-jaw heads can be exchangeably attached to the base jaws. A plurality of press-jaw head sets is stored in an associated magazine, the press-jaw head sets being for different press diameters. The press-jaw heads have two markings on at least one axial end side directly adjacent to both wedge surfaces. In addition, the two respective opposing markings of two neighboring press-jaw heads are aligned with one another. Markings that are different from one another are provided for different press-jaw head sets.
US10105741B2 Steerable roller hemming head
A steering roller head for hemming or seaming metal sheets includes a mounting flange that couples to an arm of a robot. The mounting flange is offset from a longitudinal axis of the steering roller head to reduce an operating envelope of the robot arm during a roller hemming process. The mounting flange can also be offset by a mounting angle from the longitudinal axis which allows for a further reduction in an operating envelope of the robot arm during a roller hemming process. Reducing the operating envelope of the robot arm can allow for additional robots or automated tooling to access the work piece during a roller hemming process. In addition, reducing the operating envelope of the robot arm allows for improved access to the work piece during a roller hemming process.
US10105727B2 Apparatus for preventing a cover from being drawn into an axis joint of a paint robot and related method
An arrangement for automated painting of an object includes a paint robot, a cover and a cover blocking member. The paint robot defines an axis joint about which a first portion rotates relative to a second portion. The cover covers at least a portion of the paint robot. The cover blocking member is in the form of a band carried by the paint robot and is positioned between the paint robot and the cover.
US10105721B2 Dispenser with a hermetic seal
A dispenser (1) with a hermetic seal includes a hollow containment body (2) which can be inserted in a bottle, a lower suction tube (5), a piston (7) slidable inside the containment body (2), a hollow stem (6) axially slidable inside the containment body (2), a sealing valve (8) inserted in a bottom portion (4) of the containment body (2) and interposed between the suction tube (5) and the dosing chamber (11). The sealing valve (8) is cup-shaped and the piston (7) has a lower sealing portion (7b) configured in such a way as to interact in compression with an upper edge (8a) of the sealing valve (8) making a hermetic seal between the sealing valve (8) and the piston (7).
US10105720B2 Nozzle and container for dispensing a liquid
A tip for dispensing liquid for mounting on a container. A valve includes at least two elements that are mobile in relation to one another, each mobile element including a bearing zone against the other mobile element. One of the mobile elements bears anti-microbial material on or in the immediate proximity of a part of its bearing zone forming a blocking barrier and all surfaces of the dispensing tip in contact with the inside are free of anti-microbial material.
US10105717B2 Method for operating a separator with a drive chamber under negative pressure
A separator arrangement includes a drum with a vertical axis and which is rotatably mounted in a hooded area and placed on a rotatable drive spindle. The arrangement also includes a sealed drive area containing one or more or all of the components of a separator drive, and a pump that generates negative pressure in the sealed drive area relative to the surroundings outside of the drive area.
US10105713B2 Stable aqueous composition of neutral collectors and their use in mineral beneficiation processes
The instant invention relates to a composition in form of a stable aqueous emulsion comprising a) 1-50 wt.-% of at least one water insoluble thionocarbamate collector selected from the group consisting of dialkyl thionocarbamates, alkyl alkoxycarbonyl thionocarbamates and alkyl allyl thionocarbamates, b) 1-50 wt.-% of one or a mixture of surface active agents of the general formula wherein R1 is a saturated or unsaturated, branched or linear C3 to C30 aliphatic or aromatic hydrocarbon group, R2 and R3 are independently from each other hydrogen or a C1 to C4 alkyl group, R4 is hydrogen or —CH2—COOX where X is hydrogen or sodium salt or potassium salt or ammonium salt, and n and m are independently from each other 0 to 50, c) 0.1-20 wt.-% of a mixture of at least one alcohol and at least one ether and/or ester, e) 1-90 wt.-% of water.
US10105707B2 Container for selective transfer of samples of biological material
A container for selective transport of samples of biological material or of biological origin suitable for containing at least a fluid or liquid and/or for containing at least a portion of a collecting device, the container having a selective passage portion configured to prevent exit of a fluid or liquid from the container, through the passage portion, at least in at least an operating sealed condition defined at least by a rest state of the container or by a first value of mechanical shaking of the container and/or by a first value of relative centrifugal force to which the container is subjected, and configured selectively to enable exit of the fluid or liquid from the container, across the passage portion, at least in an operating passage condition, defined at least by a corresponding second state of mechanical shaking of the container and/or wherein the container is subjected to a corresponding second relative centrifugal force.
US10105706B2 Container assembly and system for detection thereof
A closure and a container assembly are disclosed. The closure includes a first visual identifier and a second visual identifier, wherein the second visual identifier is different from the first visual identifier. The first visual identifier may be a first color, and the second visual identifier may be a second color. At least one of the first and/or second visual identifier may include a fluorescent compound having a characteristic fluorescent spectra. The first visual identifier and the second visual identifier may be provided on the annular skirt of the closure. The fluorescent compound may be provided on at least one of the closure and the container assembly and can be used to facilitate automated visualization of the fluorescent compound under fluorescence excitation light.
US10105704B2 System and method for microplate pressurization
A pressurizable sample system includes a microplate having a planar plate surface and several sample wells. Each sample well has a flange positioned circumferentially around an outer surface of the sample well and against the planar plate surface. The sample system further includes a capping plate with a planar cap surface and several caps projecting from the planar cap surface. Each cap has a geometrical configuration in complementary correspondence with the configuration of the sample well.
US10105702B2 Microfluidic methods for manipulating DNA
Techniques are provided for generating, manipulating, and measuring fluidic droplets in mixed phase systems based on establishing transient continuities between otherwise spatially separated phases. In certain methods of the invention, electrodes in contact with the continuous phases allow electrical monitoring of continuity or proximity of separated phases as a means to characterize droplets. In other methods of the invention, fluidic continuity provides a means for generating droplets, injecting or extracting the contents of droplets, and sorting droplets. Chemical techniques are also provided that use these droplet-based methods, or others, to quantify and identify nucleic acids through incorporation into hydrogel particles. The nucleic acids are entrapped either actively by chemical incorporation during gel polymerization or passively by chain entanglement. After incorporation into the hydrogel particles, the nucleic acids are solvent accessible either at the particle periphery or within internal pores for further biochemical manipulations and characterization. In one important aspect, the invention combines the high specificity, high sensitivity, and unbiased performance of clonal DNA amplification in free solution with the simplicity of permanently co-localizing the separate reaction products onto rigid substrates for myriad biochemical applications.
US10105697B2 Methods, systems, and computer program products for detecting a surface using a pipette and/or positioning a pipette
This invention relates to methods, systems, and computer program products for detecting a surface using a pipette and/or for positioning a pipette.
US10105696B2 Honeycomb structure
A honeycomb structure includes: a honeycomb structure body which includes a porous partition wall defining a plurality of cells extending from an inflow end face to an outflow end face; an inflow side plugging portion; and an outflow side plugging portion, in which the plurality of cells includes an outflow cell having a quadrangle shape in a cross-section, an inflow cell having a pentagonal or hexagonal shape in a cross-section and being formed adjacently around the outflow cell with the partition wall defining the outflow cell while surrounding the outflow cell interposed therebetween, and in a cross-section orthogonal to the extension direction of the cell, a value of a ratio of a distance Y with respect to a distance X is 1.1 to 1.8.
US10105693B2 Catalyst compositions for selective dimerization of ethylene
A catalyst composition, including a titanate of the formula Ti(OR)4 wherein each R is the same or different, and is a hydrocarbon residue; a catalyst additive, wherein the catalyst additive is a dibutyl ether a silicate, a silazane, an aromatic ether, a fluorocarbon, or a combination comprising at least one of the foregoing; and an organic aluminum compound.
US10105691B2 Multiple zeolite hydrocarbon traps
Hydrocarbon (HC) traps are disclosed. The HC trap may include a first zeolite material having an average pore diameter of at least 5.0 angstroms and configured to trap hydrocarbons from an exhaust stream and to release at least a portion of the trapped hydrocarbons at a temperature of at least 225° C. The HC trap may also include a second zeolite material having an average pore diameter of less than 5.0 angstroms or larger than 7.0 angstroms. One or both of the zeolite materials may include metal ions, such as transition, Group 1A, or platinum group metals. The HC trap may include two or more discrete layers of zeolite materials or the two or more zeolite materials may be mixed. The multiple zeolite HC trap may form coke molecules having a relatively low combustion temperature, such as below 500° C.
US10105684B2 Synthesis of transition-metal adamantane salts and oxide nanocomposites, and systems and methods including the salts or the nanocomposites
A method for preparing a transition-metal adamantane carboxylate salt is presented. The method includes mixing a transition-metal hydroxide and a diamondoid compound having at least one carboxylic acid moiety to form a reactant mixture, where M is a transition metal. Further, the method includes hydrothermally treating the reactant mixture at a reaction temperature for a reaction time to form the transition-metal adamantane carboxylate salt.
US10105681B2 Methods and materials for microorganism capture
Material complexes that capture biologicals and methods of synthesizing and using such complexes composed of fluid-insoluble material and a receptor are provided herewith. The fluid-insoluble material has reactive functionality on its surface, including hydroxyl, amino, mercapto or epoxy functionality material. The material can be agarose, sand, textile, or any combination thereof. The receptor is selected from the group consisting of mono- and poly-saccharides, heparin, or any combination thereof. Also provided are methods whereby releasing the captured biologicals is controllable.
US10105677B2 Sorbent
A method for preparing a sorbent composition includes the steps of: applying, from a solution or a slurry, a layer of a copper compound on the surface of a support material, and drying the coated support material, wherein the thickness of the copper compound layer on the dried support is in the range 1-200 μm. The precursor may be converted to a sorbent suitable for removing heavy metals from liquids or gases by applying one or more sulphur compounds to sulphide the copper compound and form CuS.
US10105676B2 Start-up system for starting reforming hydrogen production device
The invention discloses a start-up system for starting reforming hydrogen production device, the reforming hydrogen production device and the start-up system adopt methanol-water mixture as feedstock, comprising a feed riser pipe, a flame tray, an upper cover body and an igniter. The flame tray and the upper cover body are disposed on the feed riser pipe from the bottom up; the middle part of the upper cover body is provided with an aperture in communication with the feed riser pipe, the methanol-water mixture feedstock may flow from the feed riser pipe up to the aperture and be exuded from the aperture and spread around along the upper side surface of the upper cover body until flowing into the flame tray. The present invention has high ignition success rate, large methanol-water mixture burning areas and combustion flame, and can quickly restart the reforming hydrogen production device.
US10105666B2 Method for dispensing a fluid medium
The invention relates to a method for metering a fluid medium by means of a metering device in the form of a piston pump having a cylinder (Z) and a movable piston (3), wherein the cylinder (Z) and the piston (3) form a working space (A), characterized in that in a first method step a given filling quantity of the fluid medium is conveyed into the working space (A), wherein the filling quantity is greater than the predefined quantity to be metered, and in that in a further method step the piston (3) reduces the size of the working space (A) to such an extent that the quantity to be metered remains in the working space (A), wherein at the same time a valve (18, 18′) is opened so that the gas volume separated in the working space (A) and/or the excess fluid medium can flow out of the working space (A) through the piston, wherein to this end the piston (3) has at least one axially running through-channel (17, 17′) which is connected to a return line (19, 19′), and at least the controllable valve (18, 18′) and/or a non-return valve is arranged in the through-channel (17, 17′) and/or the return line (19, 19′).
US10105663B2 Stirring propeller with blades made of sheet bent along two longitudinal bends
Stirrer (M) that includes at least two blades and is able to be fixed to a rotary shaft, wherein each blade has a leading edge facing the fluid to be stirred and a trailing edge facing away from the leading edge, and wherein each blade is obtained by bending a flat metal sheet, each blade having two longitudinal bends, the length of each bend being greater than 60% of the maximum radius of the blade.
US10105662B1 Mixing systems, methods, and devices with extendible impellers
A mixing assembly includes a drum including a side wall, a top portion, and a bottom portion, in which the top portion includes a first opening for filling a substance into the drum, a second opening for mixing the substance in the drum, and a third opening for extracting the substance from the drum; and a mixer releasably disposed in the drum, including a head releasably attached to the second opening for mixing, in which the head includes a housing including an internal hollow region extending along the central axis of the head, and external threads configured to be attached to the second opening for mixing by thread engagement, a shaft disposed in the hollow region, and an impeller assembly disposed at a bottom end of the shaft for stirring the substance in the drum.
US10105660B2 Diffuser membrane and method of manufacture
A diffuser membrane and a method for manufacturing the same are provided. In the method for manufacturing, a first material is heated and extruded to form a base layer and a second material is heated and extruded to form a coating layer. The base layer and coating layer may be extruded substantially simultaneously in a coextrusion process. Accordingly, the coating may be applied to the base layer in a manner that optimizes the bonding between the two layers and provides the ability to control the thickness of the coating layer. Alternatively, the base layer is formed initially and the coating layer is subsequently formed thereover. The first and second materials have differing properties. The first material may comprise polyurethane and the second material may comprise polyurethane and PTFE.
US10105655B2 Membrane reactor with a tubular permeable membrane
A semi-porous composite membrane and a method of manufacturing the semi-porous composite membrane. The semi-porous composite membrane includes a base supporting substrate comprising α-Al2O3, an outer layer comprising silica, and an intermediate layer comprising crystalline fibers of boehmite, and at least one of a secondary metal oxide and a synthetic polymer, wherein the intermediate layer is disposed between the base supporting substrate and the outer layer. The crystalline fibers of boehmite are a length of 5-150 nm. The semi-porous composite membrane may be employed in membrane reactors.
US10105653B2 System for rinsing electrodialysis electrodes
A system for rinsing electrodialysis electrodes includes an anode input coupled to an anode of an electrodialysis (ED) system for receiving a first fluid from the anode. The first fluid is for removing ions from the anode. The system also includes an anode output coupled to the anode of the ED system for providing the first fluid to the anode. The system includes a cathode input coupled to a cathode of the ED system for receiving a second fluid from the cathode. The second fluid is for removing ions from the cathode of the ED system. The system also includes a cathode output coupled to the cathode of the ED system for providing the second fluid to the cathode. The system includes an air stripper for receiving the first and/or second fluid, and for removing oxygen and/or a chlorine gas from the first and/or second fluid.
US10105652B2 Array for processing materials
Materials (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful intermediates and products, such as energy, fuels, foods or materials. For example, systems equipment, and methods are described that can be used to treat feedstock materials, such as cellulosic and/or lignocellulosic materials, using an array of vaults.
US10105650B2 Multi-pulse injection events for a dual-fuel engine
A method includes supplying a first quantity of a first fuel to an engine and supplying a charge including a second fuel and air to the engine. The first fuel is different from the second fuel. The method further includes mixing the first fuel with the charge, supplying a second quantity of the first fuel to the engine, and igniting at least a portion of the first and second fuels in response to supplying the second quantity of the first fuel.
US10105649B2 Methods utilizing non-zeolitic metal-containing molecular sieves having the CHA crystal structure
Catalysts comprising metal-loaded non-zeolitic molecular sieves having the CHA crystal structure, including Cu-SAPO-34, and methods for treating exhaust gas incorporating such catalysts are disclosed. The catalysts can be used to remove nitrogen oxides from a gaseous medium across a broad temperature range and exhibit hydrothermal stability at high reaction temperatures.
US10105647B2 Method of reducing sulfur dioxide content in flue gas emanating from a circulating fluidized bed boiler plant
A method of reducing sulfur dioxide emissions of a circulating fluidized bed boiler plant. A first stream of sulfur-containing carbonaceous fuel is fed at a first feeding rate to a furnace of the boiler. A second stream of calcium carbonate containing absorbent having a predetermined d50 particle size is fed at a second feeding rate to the furnace. Oxygen containing gas is fed to the furnace for fluidizing a bed of particles forming in the furnace. Fuel is combusted with the oxygen and the sulfur in the fuel is oxidized to sulfur dioxide. The calcium carbonate is calcined to calcium oxide in the furnace. A portion of the calcium oxide is used to sulfate a first portion of the sulfur dioxide to calcium sulfate in the furnace.
US10105644B2 Process and absorbent for dehumidifying moist gas mixtures
The invention relates to a process for dehumidifying a moist gas mixture in which the moist gas mixtures are brought into contact with an absorbent comprising dialkylimidazolium salts and trialkyl phosphate. In addition, the invention also relates to an absorption heat pump comprising the absorbent according to the invention and to the absorbent according to the invention itself.
US10105641B2 Hydrogen purification device and hydrogen purification system using hydrogen purification device
In order to provide a hydrogen purification device in which a source gas is supplied, from which a purified gas flows out, that is easily manufacturable, and in which the pressure resistance of an hydrogen permeable membrane is high, the hydrogen purification device is configured to include a hydrogen permeable membrane allowing hydrogen to selectively permeate therethrough, two porous supports that sandwich and support the hydrogen permeable membrane from both surfaces thereof, and a casing having a space formed therein configured to accommodate reaction of the source gas and the hydrogen permeable membrane. The porous supports are contained inside the casing, an outermost edge of the hydrogen permeable membrane extends outward from the outer edges of the porous supports in at least one location, and a peripheral portion of the hydrogen permeable membrane in a vicinity of the outermost edge and the casing are airtightly sealed to each other.
US10105634B2 Compressed air-drying device
A compressed air drier includes a support base, a desiccant cartridge coupled to the support base, and a case that covers the cartridge and is coupled to the support base. The support base includes an inlet for compressed air from a compressor, an outlet for the compressed air, and a discharge port for oil and water including a drain valve device. An electrically charged oil adsorbent is accommodated between the cartridge and the case. The cartridge is filled with a desiccant. The compressed air drier dries the compressed air entering the inlet with the desiccant during a loading operation, collects the dried compressed air in the case, and discharges the dried compressed air from the outlet. The compressed air drier passes the compressed air in the case through the cartridge during an unloading operation to discharge oil and water from the discharge port.
US10105632B2 Self-supporting folded sheet material, filter elements, and methods
A pleated media pack includes a section of media configured into a tube defining an interior volume and an open opening at one end. At least some of the pleats at both ends of the media pack are inverted. In some examples, the pleats include major pleats alternating with minor pleats.
US10105627B2 Particulate filter provided with catalyst and method for manufacturing said filter
A catalyst 20 provided for a filter body for combusting PM contains activated aluminas 21 and 22, active-oxygen-release materials 23 and 24, catalytic metal 25, and alkali earth metal 26. The alkali earth metal 26 is loaded on each of the activated aluminas 21 and 22, and the active-oxygen-release materials 23 and 24. A percentage by mass of the alkali earth metal 26, loaded on the active-oxygen-release materials 23 and 24, to the active-oxygen-release material is smaller than a percentage by mass of the alkali earth metal 26, loaded on the activated aluminas 21 and 22, to the activated alumina.
US10105626B2 Sealing device of a filter system for filtering fluids
A sealing device (24) of a filter system (10) for filtering fluids, in particular of a motor vehicle, with a sealing ring (26) is described. The sealing ring (26) serves to seal a pipe (16), in particular a central pipe of a filter housing (12), that penetrates through a flange-sided opening (18) of an end plate (20), in particular of an end element of a filter element (14). The sealing ring (26) features a central section (58) that connects it with the end plate (20). The sealing ring (26) features in its axial direction on both sides of the central section (58) elastic sealing sections (60, 62) which cause each a reduction of the inner diameter of the sealing ring (26) compared with the central section (58). The elastic sealing sections (60, 62) extend freely flexibly and can be bent away from the central section (58) such that they can be pressed—when the pipe (16) is mounted—by means of prevailing fluid pressures—when the filter system (10) is operated—in radial direction against the exterior wall of the pipe (16).
US10105625B2 Method for extending turndown in a gas-liquid separator
An apparatus for extending turndown in a gas-liquid separator is presented. The apparatus includes a first mist extractor with a first operating range and a second mist extractor with a second operating range. The mist extractors can be generally of the same type, with the second operating range being different than the first operating range. A gas stream containing entrained liquid droplets flows through the first mist extractor and then through the second mist extractor. Each mist extractor coalesces and captures the liquid droplets within its own operating range, expanding the overall operating range of the separator. Additional mist extractors may be added to cover any gap between the first and second operating ranges.
US10105618B2 Wearable article and packaging for generating bubbles
A wearable article for soap bubble generation is provided as a liquid-resistant wearable article having a portion shaped to receive a body part. A web is provided integrally with the article having at least one hole adapted to form soap bubbles when the web is dipped in bubble solution and air is moved through the at least one hole. Preferably, the article has at least two films of liquid-resistant material sealed at a common edge and a pocket between the films. The pocket is shaped to receive a body part such as a hand (e.g., the article is glove/mitten-shaped). The films of the article substantially prevent the body part inside the pocket from touching the bubble solution when the web is dipped in the bubble solution while the article is being worn. Different sizes of holes may be provided in the web to generate different sizes of bubbles.
US10105617B2 Cognitive mobile device
A method and system for cognitively controlling a mobile having mobile elements controllable by a mobile stimulation pattern. Sensor data is captured from sensors detecting reactions of a baby in proximity to the mobile to a first mobile stimulation pattern and audio/video data is captured from a video camera recording reactions of the baby in proximity to the mobile. The sensor data and the audio/video data are analyzed to determine the behavior of the baby in response to the first mobile stimulation pattern and the determined behavior is compared with expected behaviors of the baby using a machine learning algorithm to learn the baby's reactions to the first mobile stimulation pattern. A second mobile stimulation pattern is selected based on the learning of the baby's reactions to the first mobile stimulation pattern and the mobile is controlled based on the second mobile stimulation pattern.
US10105615B2 System and method fluid transfer between inflatable objects
A fluid transference system, including: (a) at least two inflatable objects; (b) at least one variable-state fluid transfer conduit, interposed between a first and a second inflatable objects, the variable state conduit configured to allow fluid flow there-through in an open state and to disallow the flow in a closed state. A fluid transfer system, including: (a) an entry port; (b) an exit port; (c) a unidirectional main conduit defined between the entry port and the exit port; (d) an intermediate port; and (e) an intermediate conduit defined between the intermediate port and the main conduit, intersecting the main conduit between a first unidirectional valve and a second unidirectional valve, the main conduit defining a unidirectional fluid flow.
US10105614B2 Assembly for tactile promotion of simplicity and amusement
An assembly for tactile promotion of simplicity and amusement incorporating a quadruple of rear extraction stops; a quadruple of flexible ties attached to and extending forwardly from the rear extraction stop; a rear torso and head silhouetting sheet having a first quadruple of eyes, wherein the quadruple of flexible ties forwardly extends through the first quadruple of eyes; a quadruple of appendages having proximal ends having a second quadruple of eyes, wherein the quadruple of flexible ties further forwardly extends through the second quadruple of eyes; a front torso and head silhouetting sheet having a third quadruple of eyes, wherein the quadruple of flexible ties further forwardly extends through the third quadruple of eyes; a quadruple of front extraction stops attached to forward ends of the quadruple of flexible ties; and a twig attached to and extending downwardly from the rear and front torso and head silhouetting sheets.
US10105613B1 Connectable toy figurines
A toy set having one or more figurines is provided. A first figurine has a motor coupled to a flywheel and a drive shaft to rotate the flywheel and the drive shaft. The drive shaft engages a support surface causing translation of the first figurine on the support surface when the drive shaft is rotated. The flywheel holds the first figurine generally upright on the support surface via gyroscopic force when the flywheel is rotated. The first figurine has a body representing a torso and at least one arm extending from the body, wherein the body and the at least one arm do not rotate with the flywheel. A second figurine is connectable to the first figurine to form a self-balancing assembly at least when the drive shaft engages the support surface and the flywheel is rotated by the motor. Rotation of the drive shaft causes translation of the self-balancing assembly on the support surface.
US10105612B2 Motion determination limiting device
The present invention relates to a motion determination limiting device including a housing. An extendable rod is arranged throughout the housing. A vertical position limiting mechanism and a horizontal position limiting mechanism are sleeved outside the extendable rod in a down-to-top manner. The housing is sleeved outside the vertical position limiting mechanism and the horizontal position limiting mechanism. A lower portion of the vertical position limiting mechanism is provided with a position limiting bearing. When the user is walking, an inclination is generated to drive the vertical position limiting mechanism in the present invention to stop the extendable rod from moving upwardly and downwardly, such that the position limitation in the vertical direction can be realized. Moreover, the rotation in horizontal direction is allowed, and the swings of the user can be limited via the horizontal position limiting mechanism.
US10105611B2 Padded grate drainage system for water rides
A padded grating system comprising sheets of multiple composite members secured together with multiple support bars or battens, wherein each composite member preferably consists of an elongated rigid bar with a foam layer adhered thereto which are encapsulated by a PVC or plastic water impervious tube or sleeve that has been heated and shrunk thereon. The sheets are specifically designed to be used in connection with water rides such as the FlowRider® and can be modularly installed on site to cover certain drainage areas. The composite members are preferably made by gluing the rigid bars onto a sheet of foam and cutting the foam sheet to form the composite members, and after the tube or sleeve has been heat shrunk around each one, the ends of the composite members are then cut and sealed.
US10105610B2 Amusement ride harness apparatus, system, and method
Disclosed herein is a harness apparatus for an amusement ride that includes an elongate shaft fixedly secured at two attachment points to a passenger carriage, a fitting coupled to the elongate shaft, a harness attachment coupled to the fitting, and a harness. The fitting is freely movable along the elongate shaft between the two attachment points. The harness includes a first end and a second end. The first end of the harness is fixedly coupled to the harness attachment to secure a passenger in the amusement ride and the second end is fixedly secured to the passenger carriage.
US10105601B1 Systems and methods for rendering a virtual content object in an augmented reality environment
Systems and methods for rendering of a virtual content object in an augmented reality environment based on a physical marker are discussed herein. Virtual content objects may be rendered by a display device in an augmented reality environment based on the field of view seen through the display device and a position of a marker (and one or more linkage points associated with the marker) in the real world. When rendered in the augmented reality environment, the virtual content objects may be visualized from any angle, from the exterior or interior of the object, and manipulated in response to user input. Virtual content objects and/or user visualizations of virtual content objects may be shared with other users (local and/or remote), enabling multiple users to potentially build, modify, and/or interact with a virtual content object simultaneously and/or cooperatively.
US10105593B2 File prefetching for gaming applications accessed by electronic devices
Techniques introduced here enable cloud-based file prefetching for gaming applications running on electronic devices. The electronic devices store certain gaming data files on a remote storage server and preload some of the files locally to include file access efficiency. Gaming data file access patterns on the electronic devices are analyzed, individually and collectively, using a cloud service to detect global access patterns and help determine which gaming data files to preload on each of the electronic devices.
US10105587B2 Free heel touring-style ski binding slip differential cassette
The present invention pertains to a spring or alternative elastic, resilient, compressible media cassette for a touring-style ski binding, such as used in alpine touring or telemark skiing. The touring ski binding slip differential cassette provides the skier with variety of tuning options to manually adjust binding size, stiffness, and range of motion. Manual adjustment of binding size, stiffness, and range of motion enhances the touring ski binding ease of use, adjustability, and overall capabilities, further progressing the touring ski binding. In addition, the slip differential cassette provides the touring skier with cassette presets that match each skier to a predetermined binding size, stiffness, and range of motion based on skier weight and ability.
US10105584B1 Body protective padding with non-bursting gas cells
Body protection padding with non-bursting gas cells preferably includes at least one base shell, an inside gas cell impact layer and an outside gas cell impact layer. The gas is preferably air, but could be any other suitable gas, such as pure nitrogen or argon. Body protection padding includes shoulder-chest pads, knee pads, hip pads, thigh pads and any other type of sports protective padding. The gas cells in the inside and outside gas cell impact layers do not burst upon impact. The at least one base shell is typically used in the body protection padding. Each gas cell layer includes a plurality of gas cells created between two plastic sheets. The inside and outside gas cell impact layers may be permanently or removably attached.
US10105583B2 Interactive projectile-gaming system
A projectile throwing game. The present system is a game that involves throwing a projectile into the interior of a receiving unit. The receiving unit is equipped with a sensor that detects when a projectile enters the receiving unit. The receiving unit additionally has a transceiver configured to relay information to a processor unit. The processor unit is connected to a visual output and displays virtual images representing the physical receiver units. The object of the game is to throw specific projectiles into specific receiver units, as instructed by the virtual images.
US10105580B2 Iron type golf club set
A set 2 includes two or more iron type golf clubs 4 having loft angles different from each other. Each club 4 includes a shaft sf, a head hd, and a grip gp. The head hd includes a top surface 10, a sole surface 12, and a face surface 14 having a face line gv. The sole surface 12 includes a leading edge E1 and a trailing edge E2. In a planar view of the sole surface 12, the trailing edge E2 is curved so as to project toward a face side. A sole width WSc at a middle position of the face line gv is increased as the loft angle is increased.
US10105579B1 Golf club head with a compression-molded, thin-walled aft-body
A multiple-material golf club and a method for forming said golf club is disclosed herein. The multiple-material golf club preferably is a driver that has a metal face cup and a thin-walled, compression molded, composite aft body with precise IML and OML geometry. The molding composite used to form the compression molded aft body preferably comprises a plurality of randomly oriented, pre-spread carbon fiber bundles and a thermoset or thermoplastic matrix material.
US10105577B2 Golf balls having dual-layered cores with metal-containing centers and thermoset outer cores
Multi-piece golf balls containing a dual-core structure are provided. The core structure includes a small, heavy inner core (center) having a relatively high specific gravity and a surrounding outer core layer having a relatively low specific gravity. The core structure may have different hardness gradients. In one preferred embodiment, the inner core and outer core each has a positive hardness gradient. The center of the core comprises a metal material such as copper, steel, brass, tungsten, titanium, aluminum, and alloys thereof. The outer core layer preferably is formed from a thermoset composition such as polybutadiene rubber. The resulting ball has high resiliency and good spin control.
US10105572B2 Athletic performance user interface
Athletic data may be recorded and displayed using a computing device such as a mobile communication device during performance of physical activity. In some examples, the device may provide options for defining and recording athletic activity performed by the user. Such options may include various content item selection and rendering controls. Additionally or alternatively, route selection and controls may be provided through the device. Recorded activity data may further be transmitted to a remote site through a network.
US10105571B2 Systems and methods for sensing balanced-action for improving mammal work-track efficiency
An example system includes one or more sleeves, each configured for attachment to a leg and comprising a pressure sensor, an accelerometer and a magnetometer. A processor processes sensor signals from the pressure sensor, the accelerometer and the magnetometer to estimate action (A) and work (W) using event detections of peak stance and valley swing events associated with leg movement, for optimizing energy efficiency for maintaining a balance of the body leaning forward in a gravity pull-down force, with the periodic upward force of the sequential foot-thrusts with the toes.
US10105568B2 Stair climber apparatuses and methods of operating stair climber apparatuses
Stair climber apparatuses have a control circuit that controls the speed and torque of an electric motor and controls an output torque direction of the electric motor. The control circuit controls the speed of the electric motor and the output direction of the electric motor to maintain a constant speed of travel of a plurality of stairs in a downward direction along an inclined support when an operator is stepping on the plurality of stairs in an upward direction. When a change in output torque direction of the electric motor torque is required to maintain the constant speed of travel of the plurality of stairs in the downward direction along the inclined support, the control circuit controls the speed of the electric motor down to a zero speed. Methods are for operating the stair climber apparatuses.
US10105563B2 Fire extinguishing device and method thereof
A fire extinguishing device includes a pressure fire extinguishing agent and an accommodating space (1) capable of storing the fire extinguishing agent. A lot of cut-through ejecting openings (2) are defined in an outer wall of the accommodating space (1), and the ejecting openings (2) are plugged by plugging pieces (3) made of a pressure-resistant meltable fireproof material. In the case of a local temperature rise or an open fire of the target in an airtight or semi-airtight space, the plugging piece (3) on the ejecting opening (2) is melted to make the ejecting opening (2) cut through, the pressure fire extinguishing agent stored in the accommodating space is further ejected from the ejecting opening (2) to suppress a fire point or a high temperature point of the target, therefore the fire is controlled at the first time.
US10105562B2 Hermetically sealed portable fire extinguisher with pressure indicator
A portable fire extinguisher is disclosed which includes a cylinder for storing a pressurized fire extinguishing agent and has a neck portion defining an outlet, and a flexible hermetic seal supported across the outlet of the cylinder, wherein the flexible hermetic seal is adapted and configured to transition between: an unexpanded condition corresponding to an unpressurized cylinder; an expanded condition corresponding to a pressurized cylinder; and a bursted condition corresponding to an opened cylinder.
US10105555B2 System and method for determining radiation dose to circulating blood
The present invention discloses systems and methods for calculating the radiation doses received by circulating blood cells. The present method may be applicable for calculating the radiation doses by circulating blood cells through any site in a patient. The present invention also discloses computer systems for calculating radiation doses received by circulating blood cells in a patient.
US10105552B2 Formulations of histone deacetylase inhibitor and uses thereof
Dosing regimens, methods of treatment, controlled release formulations, and combination therapies that include an HDAC inhibitor, or a pharmaceutically acceptable salt thereof, are described.
US10105551B2 System for optical stimulation of target cells
Various systems and methods are implemented for controlling stimulus of a cell. One such method is implemented for optical stimulation of a cell expressing a NpHR ion pump. The method includes the step of providing a sequence of stimuli to the cell. Each stimulus increases the probability of depolarization events occurring in the cell. Light is provided to the cell to activate the expressed NpHR ion pump, thereby decreasing the probability of depolarization events occurring in the cell.
US10105549B2 Modulating function of neural structures near the ear
Stimulation of the facial nerve system (e.g., electrically, electromagnetically, etc.) in ischemic stroke patients will cause dilation of occluded arteries and dilation of surrounding arteries, allowing for blood flow to circumvent the obstruction and reach previously-deprived tissue. The device approaches the facial nerve and its branches in the vicinity of the ear. In use, the device can be inserted into the ear canal and/or placed in proximity to the ear in order to stimulate the facial nerve system non-invasively (e.g., using an electromagnetic field). The device can be used in the emergency treatment of acute stroke or chronically variations for long-term maintenance of blood flow to the brain and stroke prevention. Additional embodiments of the device may be adapted for use on different regions of the body.
US10105542B2 Patient remote and associated methods of use with a nerve stimulation system
A neurostimulation system having an external or an implantable pulse generator programmed to innervate a specific nerve or group of nerves in a patient through an electrode as a mode of treatment, having a patient remote that wirelessly communicates with the pulse generator to increase stimulation, decrease stimulation, and provide indications to a patient regarding the status of the neurostimulation system. The patient remote can allow for adjustment of stimulation power within a clinically effective range and for turning on and turning off the pulse generator. The patient remote and neurostimulation system can also store a stimulation level when the pulse generator is turned off and automatically restore the pulse generator to the stored stimulation level when the pulse generator is turned on.
US10105541B2 Selective stimulation systems and signal parameters for medical conditions
Devices, systems and methods are provided for targeted treatment of a variety of conditions, particularly conditions that are associated with or influenced by the nervous system, such as pain. Targeted treatment of such conditions is provided with minimal deleterious side effects, such as undesired motor responses or undesired stimulation of unaffected body regions. This is achieved by directly neuromodulating a target anatomy associated with the condition while minimizing or excluding undesired neuromodulation of other anatomies.
US10105540B2 Optimization of application of current
Apparatus is provided, comprising: (a) an implantable excitation unit, configured to induce action potentials in a nerve of a subject by applying an excitatory current; (b) an implantable blocking unit, configured to block the induced action potentials from propagating along the nerve by applying a blocking current; and (c) an extracorporeal controller, comprising circuitry configured: (i) to wirelessly drive the excitation unit to apply the excitatory current, (ii) in a first mode, to wirelessly drive the blocking unit to apply the blocking current while not driving the excitation unit to apply the excitatory current, (iii) in a second mode, to wirelessly drive the blocking unit to apply the blocking current while driving the excitation unit to apply the excitatory current, and (iv) to wirelessly alter a parameter of the blocking current, based on sensing performed while the extracorporeal controller is in the second mode.
US10105537B2 Receptacle for pacemaker lead
A lead receptacle having a lumen configured to traverse from an outer side of an outermost intercostal muscle to an inner side of an innermost intercostal muscle of an intercostal space of a patient and to support a lead traversing through the lumen. The lumen being configured to support one or more cardiac leads traversing through the intercostal space.
US10105530B2 Fluid delivery system with high and low pressure hand manifold
A fluid delivery system is provided and includes a power injector supporting a high pressure syringe. The fluid delivery system further includes a manifold and a low pressure hand-operated syringe. The manifold generally includes a plurality of fluid control valves in series fluid communication. A first fluid control valve of the plurality of fluid control valves has a first port, a second inlet port, and a third port. The third port of the first fluid control valve is in fluid connection with a first port of a second fluid control valve. The low pressure hand-operated syringe is in fluid connection with the first port of the first fluid control valve, and the high pressure syringe is in fluid connection with the second port of the first fluid control valve. The fluid control valves may be multi-position stopcock valves.
US10105526B2 Microneedle system and method for the production thereof
A microneedle system and method for production thereof. From a board a web grating is produced which has a plurality of grating nodes each defined by three apertures and which has web grating wedges. The microneedle system comprising a board and a plurality of openings delimited circumferentially by a web grating, having at each opening at least one web grating wedge having a needle-shaped tip which projects from the board and which is oriented at least approximately normal to the board. Web grating wedges having needle-shaped tips protrude into each aperture from at least three different directions. In order to produce openings, at least all the web grating wedges which protrude into an aperture are bent by a punch and the needle-shaped tips thereof are oriented normal to the plane of the web grating. At least two web grating wedges are arranged at each opening.
US10105525B2 Fluid delivery catheter with pressure-actuating needle deployment and retraction
A fluid delivery catheter that uses micro-needles for fluid delivery though a vessel wall. The catheter may provide fluid delivery therapy for various procedures, such as, for example, delivery of tumescent fluid or renal denervation. The catheter includes an elongate member with deployable and retractable needles disposed about a distal end of the elongate member. The needles may be disposed radially about the distal end and/or along a length of the distal end.
US10105524B2 Article with hollow microneedles and method of making
The present application provides articles (10) having a polymeric substrate (12) with a plurality of solid and/or hollow microneedles (20) extending therefrom. Each solid microneedle is formed by a molding process and the microneedle has body with first (30) and second cavities (40) extending therein. The hollow microneedles are formed by removing a portion of the polymeric material disposed between the first cavity and the second cavity. A method for determining the location of a microneedle in an article comprising solid microneedles is also provided. The method comprises directing electromagnetic radiation toward an article comprising a plurality of microneedles and imaging the article.
US10105519B2 Variable diameter medical balloon
An apparatus for performing a medical procedure includes a balloon comprising an inflatable body. A first releasable or frangible connection is provided to maintain the body at a first diameter up to a first inflation pressure, and to release, such as by disconnecting, and thus allow the body to assume a second diameter, such as at a second inflation pressure greater than the first inflation pressure or upon a manual release of the connection by a clinician. Multiple releasable or frangible connections may be provided, including between portions (folds) of the inflatable body of the balloon. This disclosure also pertains to a non-compliant or semi-compliant balloon having a first inflation diameter corresponding to a first range of inflation pressures and a second inflation diameter corresponding to a second inflation pressure greater than the first range of inflation pressures.
US10105518B2 Soft lock wire guide and neuro-surgery assembly using same
A neuro-surgery assembly includes a neuro-catheter slidably received over a wire guide. The wire guide includes an inner tube positioned within an elongate hollow tube that includes a pattern of openings at its distal segment to provide an atraumatic tip for reaching sensitive locations in a brain. The wire guide is changeable between a stiff condition in which the inner tube is pressurized and a soft condition in which the inner tube is depressurized. The user may switch between the stiff and soft conditions to negotiate the tortuous pathway to a brain treatment site without a need to swap out to a different wire guide to support advancement of the neuro-catheter.
US10105516B2 Catheter with improved torque transmission
A catheter has a deflection beam and a single continuous puller wire to effectuate bi-directional deflection. A joint between a catheter body and a deflectable distal section effectively transmits torque from a control handle. The joint includes two open-shaped brackets, each affixed to a respective side of the flat deflection beam to form a closed-shaped hollow body that bridges and circumferentially encircles the beam. Each bracket has through-holes into which thermoplastic material of the catheter body and the deflectable distal section can melt and migrate to form interlocking nodes.
US10105514B2 Methods and apparatus for inserting multi-lumen split-tip catheters into a blood vessel
A method of performing a medical procedure, includes providing a catheter including a first lumen in fluid communication with a first distal opening and a second lumen in fluid communication with a second distal opening, advancing a distal end of a first intra-catheter stiffener element through the first lumen and out of the first distal opening, coupling the first intra-catheter stiffener element to the catheter, advancing a distal end of a second intra-catheter stiffener element through the second lumen and out of the second distal opening, coupling the second intra-catheter stiffener element to the catheter, and advancing the catheter into a patient.
US10105512B1 Antimicrobial catheter jacket
An antimicrobial device for use with a catheter includes a jacket having a central opening for receiving a catheter in sliding engagement therewith and an antimicrobial means disposed within the jacket for reducing the number of microbes on the catheter or the skin of the patient. When the catheter is inserted through the central opening of the jacket, the antimicrobial means acts to disinfect the exterior surface of the catheter.
US10105508B2 Headgear, interface and an assembly
This invention relates to a headgear comprising a semi-rigid frame engageable with the head of a user and a releasable connection system for releasable connection with a user interface, wherein the frame extends generally about a rear region of a user's head, generally about an upper region of a user's head, and generally about an ear or both ears of a user.
US10105507B2 Device for providing an auxiliary air passage to the trachea
A device for providing an auxiliary aft passage to a trachea comprises a cannula member, a trocar member and a cap member. The cannula member has longitudinal walls defining a channel, proximal and distal openings at opposed ends of the channel, and a side opening near a distal end of the longitudinal walls. The trocar member includes a proximal flanged end and an elongated member extending from the flanged end, the elongated member being insertable within the channel and having a pointed end projecting through the distal opening when the elongated member is inserted in the channel. The cap member has an inner cavity and is adapted to sealingly engage the cannula member, when the device is not in use, such that the longitudinal walls of the cannula member are contained within the inner cavity and the sharp tip of the trocar member is protectively housed within the cap member.
US10105506B2 Setup automation for respiratory treatment apparatus
A respiratory treatment apparatus implements pressure delivery control settings by improved set-up procedures. In such an embodiment, a processor may automate setting of parameters for delivering a controlled flow of breathable gas. Data sets of pressure delivery parameter settings may be associated with one or more respiratory pathology indicators. The respiratory pathology indicators may each represent a different respiratory condition diagnosis. The processor may then prompt for an input of at least one of the respiratory pathology indicators. In response to the input, a particular set of pressure delivery parameter settings associated with the input respiratory pathology indicator may then serve as a basis for setting controls for delivering a controlled flow of breathable gas for respiratory treatment.
US10105505B2 Means and method for fluid pulses
A pulsating therapeutic inhaler generating pneumatic pulses for treating respiratory disorders. The inhaler includes: a linear passage that has an elongate axis and is configured to conduct a fluid flow in a laminar manner; a patient interface fluidly connectable to the patient's respiratory tract having an aperture fluidly connectable to the passage; and a shutter disposed between the passage and the aperture configured to modulate a fluid pressure within the fluid flow. The shutter includes a disc having at least one cutout and rotating about an axis parallel to the passage axis. The cutout has four cornered perimeter thereof with two side portions and two circumferential arcs configured relative to the rotation axis. The side portions are circumferentially anti-symmetrical relative to the aperture.
US10105496B2 Automatic injector
An automatic injector includes a cover extending along a longitudinal axis. A syringe for injecting a drug is arranged inside the cover, and includes a needle, a needle protector, a body, a plunger, and a rod for pushing the plunger into the syringe body, which is moved axially forwards by a resilient load force exerted by a first spring during an injection. The syringe also includes a tip for protecting the needle, which is axially movable about the needle and against a resilient load force exerted by a second spring between a forward position in which the tip surrounds the needle and a retracted position in which the needle is uncovered. A mechanism blocks the forward movement of the rod. The mechanism is deactivated as the tip is moved towards the retracted position and is reactivated during the injection when the tip is moved towards the forward position.
US10105486B2 Fluid path connectors and container spikes for fluid delivery
A fluid connector includes an extending section having a spiked end to pierce a container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes first and second abutment members. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port, and the second abutment member, which is spaced from the first abutment member, is adapted to abut a second or fluid side of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the at least one air conduit. The check valve may be positioned within the extending section.
US10105483B2 Medicine dispensing device
Some embodiments of a wearable, disposable medicine dispensing device may include a piston rod that is advanced to dispense medicine from the device. A rotational motor may be coupled to a drive mechanism so as to carry out a certain number of revolutions and thereby displace the piston rod by a desired distance. Such a device can be used in a method of dispensing liquid medicine.
US10105482B1 Enveloping assembly and method for sterilized and static resistant ordering of medical wires and tubes
An enveloping assembly and method for sterilized and static resistant ordering of medical wiring and tubes holds elongated electrical and tubular members for ordering, to prevent the elongated members from tangling or falling into a disorganized arrangement, especially near a medical procedure. The assembly comprises an outer panel defined by a flexible, sterilized fabric. An inner panel is disposed coplanar to the outer panel, lying within the edges of the outer panel. The inner panel is flexible and static charge resistant. The inner panel enables enveloping of the elongated members while preventing static discharge. The inner panel envelopes the elongated members by moving opposing edges of the inner panel to form a unitary sleeve, wherein the outer panel can envelope the unitary sleeve to protect the assembly from contamination. A fastener joins with the outer panel to fasten the unitary sleeve closed and detachably attach to a mounting surface.
US10105477B2 High flow rate dialysis catheters and related methods
High flow rate catheters, and related methods, are useful in dialysis and other procedures. A catheter according to the invention comprises a hub and a generally elongated conduit. The conduit has a substantially continuous and smooth wall. The conduit also defines at least one lumen and has a length extending from a proximal end to a distal end of the conduit. The proximal end is coupled to a hub and the distal end has an opening in communication with the lumen. The conduit has a conical shape which tapers along the length.
US10105474B2 Synchronizing breast pumping with infant feeding
A system for synchronizing one or more breast-pumping sessions of an individual (such as a mother) and milk consumption by a second individual (such as a baby or infant) is described. In particular, based on measurements of a volume of the collected milk as a function of time and received information specifying milk consumption by the second individual as a function of time, a control circuit may determine a need for milk. Then, the control circuit may provide feedback based on the determined need for milk that synchronizes the one or more breast-pumping sessions and the milk consumption. For example, the feedback may alert the individual to initiate a breast-pumping session and/or may provide a signal to a breast pump that initiates a breast-pumping session.
US10105471B2 Reduced pressure treatment system
A wound treatment appliance is provided for treating all or a portion of a wound. In some embodiments, the appliance comprises a cover or a flexible overlay that covers all or a portion of the wound for purposes of applying a reduced pressure to the covered portion of the wound. In other embodiments, the wound treatment appliance also includes a vacuum system to supply reduced pressure to the site of the wound in the volume under the cover or in the area under the flexible overlay. Methods are provided for using various embodiments of the invention.
US10105470B2 Mobile instrument assembly for use as part of a medical/surgical waste collection system, the assembly including a vacuum source to which a mobile waste collection cart can be releasably attached
A waste collection system for collecting waste during medical/surgical procedures including a mobile container cart with a waste container. A container cart is selectively coupled to a suction cart that includes a vacuum pump. The connection of the carts results in the connection of the vacuum pump to the waste container. The vacuum pump draws a vacuum that results in waste being drawn through a suction line into the waste container. The container cart holds instruments that can be removably attached to the container cart. This facilitates the configuration of the container cart for the specific procedure for which it is necessary to draw a suction.
US10105467B2 Biocompatible polymer compositions for tissue void filling
Biodegradable, bioabsorbable cross-linked polymer tissue scaffolds for filling a void in human or animal soft tissue, such as a surgical or other wound, are disclosed. Drugs incorporated into the polymer backbone and/or loaded into the matrix are released directly to the target site. Additional non-toxic chemical constituents can be used to tune the hydrophilio hydrophobic and other physical properties of the cross-linked polymer tissue scaffolds, and incorporating brominated or iodinated constituents provides radio-opacity. The radio-opaque cross-linked polymer tissue scaffolds can assist in the targeting of radiation therapy.
US10105465B2 Biodegradable medical adhesive or sealant composition
The present invention provides a biodegradable medical adhesive or a sealant composition containing an oxidized glycosaminoglycan and a polyamine. The composition of the present invention exhibits improved effects in biodegradation, coating property, gelation time, hemostatic capacity, adhesive force, moisture absorptive capacity and the like, and thus can be applied to various medical uses in which a medical adhesive or sealant can be used, such as biotissue adhesion, filling, coating, adhesion prevention, wound covering, leakage prevention and hemostasis.
US10105458B2 Dry heat sanitizer and method of use
A sanitizer system and method of use is disclosed. The sanitizer system quickly sanitizes and cools targeted objects and secures the targeted sanitized objects for later use, without the need to transfer the objects to a separate container. In one embodiment, the sanitizer system comprises a cassette having a body and a removable lid that, when joined, form an airtight chamber for containing an object for sterilization. A pressure control element of the system is configured to fluidly engage with the cassette to produce a pressure-controlled environment within the airtight chamber. A heating element of the system, which is interconnected and in thermal communication with the airtight chamber, is configured to provide heat to the airtight chamber. The chamber temperature is raised to a desired temperature for a period of time sufficient to sanitize the object. A cooling element of the system is configured to cool the chamber and the object.
US10105457B2 System and method for damaging parasites
A method of damaging a parasite while being a resident in or on a surface of a body of a mammal. The method comprises irradiating the parasite with ultrasound radiation at a frequency of from about 1 MHz to about 2.6 MHz for a period of at least one second.
US10105451B2 Therapeutic retroviral vectors for gene therapy
The invention provides improved compositions and methods for achieving gene therapy in hematopoietic cells and hematopoietic precursor cells, including erythrocytes, erythroid progenitors, and embryonic stem cells. The invention further provides improved gene therapy methods for treating hematopoietic-related disorders. Retroviral gene therapy vectors that are optimized for erythroid specific expression and treatment of hemoglobinopathic conditions are disclosed.
US10105448B2 Combined enteropathogen recombinant construct
The inventive subject matter relates to a construct comprising antigens derived from multiple enterobacteria including Campylobacter jejuni capsule polysaccharide polymer, enterotoxigenic Escherichia coli recombinant polypeptide construct and lipopolysaccharide from Shigella spp. The subject invention also relates to a method of inducing an immune response utilizing the inventive composition.
US10105444B2 Compositions and methods for treating diseases of the nail
Methods and compositions for treating disorders of the nail and nail bed. Such compositions contain a vehicle in which all components of the composition are dissolved, suspended, dispersed, or emulsified, a non-volatile solvent, a wetting agent, and a pharmaceutically active ingredient that is soluble in the non-volatile solvent and/or a mixture of the vehicle and the non-volatile solvent, which composition has a surface tension of 40 dynes/cm or less and has continuing spreadability, and which composition is effective in treating a disorder of the nail or nail bed.
US10105440B2 Synthetic derivatives of MPL and uses thereof
In one aspect, the present disclosure provides compounds of formulae I and II. In another aspect, a compound of formula I or II is formulated into compositions with an antigen, optionally with a vesicle. In some embodiments, compositions are administered intramuscularly.
US10105439B2 Polysaccharide fraction originating in persimmon leaf with immunostimulating activation and antitumor activation and method for manufacturing same
A persimmon leaf-derived polysaccharide fraction consisting of 60-80 wt % of neutral sugar and 18-39 wt % of uronic acid, and 0.5-10 wt % of 3-deoxy-D-manno-2-octulosonic acid (KDO) analogs, the wt % based on the total weight of the polysaccharide fraction.
US10105437B2 Epitopes related to coeliac disease
The invention herein disclosed is related to epitopes useful in methods of diagnosing, treating, and preventing coeliac disease. Therapeutic compositions which comprise at least one epitope are provided.
US10105436B2 Smallpox vaccine for cancer treatment
Disclosed herein are methods and compositions related to therapy for cancer. More specifically, the disclosed methods and compositions are related to the use of smallpox vaccine to induce an effective anti-tumor immune response.
US10105432B2 Targets of acinetobacter baumannii
The present invention provides antigenic polypeptides expressed during an infection by a pathogenic organism, such as Acinetobacter and compositions comprising these polypeptides. The invention further provides compositions for use in treating, preventing or detecting a bacterial infection, in particular vaccine compositions using the antigenic polypeptides. The invention further provides antibodies directed to said antigenic polypeptides.
US10105429B2 Escherichia coli vaccine combination
The invention provides an immunogenic composition comprising a combination of (i) bacterial Ig-like domain protein fragment (orf405B) having the amino acid sequence set forth in SEQ ID NO:2 or a protein having at least 80% similarity thereto, and (ii) putative Lipoprotein (orf3526) having the amino acid sequence set forth in SEQ ID NO:8 or a protein having at least 80% similarity thereto.
US10105428B2 Peptides and combination of peptides and scaffolds for use in immunotherapy against renal cell carcinoma (RCC) and other cancers
The present invention relates to peptides, proteins, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated T-cell peptide epitopes, alone or in combination with other tumor-associated peptides that can for example serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses, or to stimulate T cells ex vivo and transfer into patients. Peptides bound to molecules of the major histocompatibility complex (MHC), or peptides as such, can also be targets of antibodies, soluble T-cell receptors, and other binding molecules.
US10105426B2 Immunostimulatory combinations
The present invention provides immunostimulatory combinations. Generally, the immunostimulatory combinations include a TLR agonist and a TNF/R agonist. Certain immunostimulatory combinations also may include an antigen.
US10105414B2 Peptides derived from RS1 which down-regulate glucose absorption after a glucose rich meal and increase insulin sensitivity
The present invention relates to a pharmaceutical composition comprising a (poly)peptide which comprises or consists of QEP or a QEP derivative thereof a nucleic acid molecule encoding said (poly)peptide or a vector comprising said nucleic acid molecule, for use in the prevention or in the treatment of a disease or disorder caused by, physiologically linked to or associated with glucose and/or galactose uptake, wherein said pharmaceutical composition is to be administered under a high-sugar condition. Furthermore, the pharmaceutical composition of the invention is for use in increasing insulin sensitivity. The invention further relates to a food composition comprising said (poly)peptide. The invention further relates to a method of screening for and/or identifying a compound suitable to prevent or treat said disease or disorder under a high-sugar condition. The invention further relates to a method of screening for and/or identifying a compound which modulates ornithine decarboxylase (ODC), which is capable of inhibiting (SGLT1-mediated) glucose and/or galactose uptake into a cell expressing ODC and/or which is capable of increasing the inhibitory effect of an inhibitor of glucose and/or galactose uptake into a cell expressing ODC. The invention further relates to a method for predicting a patients non-response or response to said (poly)peptide, to a method for stratifying a patient for prevention or treatment with said (poly)peptide and to a kit for determining whether a patient suffering from said disease or disorder is a non-responder or responder to said polypeptide. The invention further relates to a method of developing and/or designing a compound/drug suitable to prevent or treat said disease or disorder.
US10105413B2 Semaphorin 3A for treatment of systemic lupus erythematosus
The subject matter relates to Semaphorin 3A (Sema3A) and its use in treatment and prognosis of Systemic Lupus Erythematosus (SLE). Provided are, inter-alia, methods of treating a subject afflicted with SLE, comprising administering to the subject a pharmaceutical composition comprising isolated Sema3A. Further provided are methods for prognosis of SLE, comprising measuring Sema3A serum concentration in a subject in need thereof.
US10105411B2 Compositions and methods for modulating AT2R activity
New polypeptide agonists of AT2R are disclosed, as well as pharmaceutical compositions comprising the agonists, methods of their use in the treatment of diseases, conditions or disorders characterized by insufficient AT2R activity or excessive AT1R activity, and methods of their use as laboratory reagents for research purposes.
US10105410B2 Heparanase inhibitory peptides and use thereof for treating clinical pathologies
The present invention is directed to peptides derived from certain domains of tissue factor pathway inhibitor (TFPI) for use in the treatment of solid tumors and diseases or disorders associated with abnormal clotting.
US10105409B2 Therapeutic use of chardonnay seed products
The present disclosure relates to health benefits of Chardonnay seed products.
US10105405B2 Compositions and methods for enhancing brain function using acetyl-L-carnitine, huperzine A and ginkgo biloba
A nutritional supplement composition is formulated for oral administration and enhances cognitive function. It includes huperzine A, Ginkgo biloba, and acetyl-L-carnitine. The huperzine A, acetyl-L-carnitine, and Ginkgo biloba together account for at least 80 wt % of a dosage unit of the composition. The Ginkgo biloba is about 5.0% to about 12.0%, by weight of the huperzine A, acetyl-L-carnitine and Ginkgo biloba. The Ginkgo biloba and acetyl-L-carnitine are in a ratio of y:z respectively, wherein y is between about 690 and 1,030 for Ginkgo biloba and z is between about 8,000 and 12,000 for acetyl-L-carnitine.
US10105404B2 Oncolytic herpes simplex virus and therapeutic uses thereof
The present invention relates to variants of herpes simplex virus (HSV) that selectively infect and replicate in cancer cells, including HSV strains that selectively infect and replicate in bladder cancer cells. Preferred HSV of the invention have intact endogenous Us11 and Us12 genes and have genes encoding ICP34.5 replaced with a gene encoding Us11 fused to an HSV immediate early (IE) promoter. The variant HSV of the invention also comprise one or more additional heterologous genes encoding immunomodulatory polypeptides. Methods and compositions using these variant HSV, for example, for treating cancer in a subject, are also provided.
US10105403B2 Methods of treating iron deficiency to prevent iron-deficiency anemia by administration of Lactobacillus plantarum
The present invention relates to the use of at least one strain of Lactobacillus plantarum chosen from the group comprising Lactobacillus plantarum 299, DSM 6595, Lactobacillus plantarum 299v, DSM 9843, Lactobacillus plantarum HEAL 9, DSM 15312, Lactobacillus plantarum HEAL 19, DSM 15313, Lactobacillus plantarum HEAL 99, DSM 15316, and a part thereof, for the preparation of a composition for increasing the absorption of at least one kind of metal/metal ion in a mammal, preferably a human.
US10105402B2 Catecholamine production accelerator, and therapeutic and preventive agent and therapeutic and preventive food composition for diseases caused by catecholamine deficiency
An object of the present invention is to provide: a catecholamine production accelerator comprising a natural product as an active ingredient; a therapeutic agent and preventive agent for diseases caused by catecholamine deficiency; and food compositions for the treatment or prevention of diseases caused by catecholamine deficiency. Provided are: a catecholamine production accelerator comprising a dry powder, ground product and/or extract of an earthworm as an active ingredient; a therapeutic agent and preventive agent for a disease caused by catecholamine deficiency; and loud compositions for the treatment or prevention of a disease caused by catecholamine deficiency. It is preferred that the disease caused by catecholamine deficiency be selected from the group consisting of Alzheimer's disease and Parkinson's disease.
US10105395B2 Microvesicles (MVs) derived from adult stem cells for use in the therapeutic treatment of a tumor disease
The invention is in the field of therapeutic treatment of tumors. The inventors have found that microvesicles derived from adult stem cells exert a remarkable anti-tumor effect when administered to a patient affected by a tumor disease. Preferred microvesicles are derived from a bone marrow-mesenchymal stem cell, a glomerular mesenchymal stem cell or a non-oval liver stem cell.
US10105392B2 Isolated renal cells and uses thereof
The invention is directed to isolated renal cells, including tubular and erythropoietin (EPO)-producing kidney cell populations, and methods of isolating and culturing the same, as well as methods of treating a subject in need with the cell populations.
US10105391B2 Chimeric antigen receptor and methods of use thereof
The present disclosure provides a heterodimeric, conditionally active chimeric antigen receptor (CAR), and a nucleic acid comprising a nucleotide sequence encoding the CAR. The present disclosure provides cells genetically modified to produce the CAR. A CAR of the present disclosure can be used in various methods, which are also provided.
US10105390B2 Process for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles
Process for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity; it also promotes cell adhesion and osteogeneration. In dentistry, it may be used in toothpastes, mouthwashes, chewing gums, gels and fluoride varnishes as a remineralising agent of dentine and enamel. It is based on two solutions formed by calcium chloride and sodium citrate on the one hand, and by sodium monohydrogenophosphate and sodium carbonate with a fluoride compound on the other, which are mixed at room temperature. The process is eco-efficient and eco-friendly, as it does not leave any acid residue; it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride, which enhances its remineralising action, is obtained.
US10105389B1 Method and compositions for treating cancerous tumors
The present invention relates to the use of chlorine dioxide compositions for treating cancerous tumors. The present invention relates to compositions and methods for treating cancerous tumors, including naïve, metastatic and recurrent cancers. The compositions comprise chlorine dioxide in an effective amount, which is injected into the cancerous tumor at least once, and often at least several times over the course of treatment. The chlorine dioxide compositions are injected directly into the cancerous tumor and the resulting tumor is effectively eliminated from the patient or subject over a period of one to several days to a few weeks, often after a single injection, or multiple injections at one session into the tumor. Often, an initial injection or multiple injections at one session are sufficient to dissolve the cancerous tumor. Often the cancer is eliminated (as evidenced by no remission) in a period of no more than several days to about two-three months and does not recur.
US10105385B1 Adjuvant composition
Provided is an adjuvant composition comprising a nucleic acid comprising a double-stranded RNA bound to a single-stranded DNA, the double-stranded RNA consisting of a nucleotide sequence of SEQ ID NO: 1 and its complementary sequence, the single-stranded DNA consisting of a nucleotide sequence of SEQ ID NO: 2. Also provided is a vaccine composition comprising the adjuvant composition and an antigen or an antigen component. The nucleic acid contained in the adjuvant composition is a chemically synthesizable nucleic acid having potent adjuvant activity and high safety.
US10105378B2 Enrichment methods for preparing tannic acid compositions
Methods for preparing tannic acid-containing compositions (e.g., pharmaceutical compositions, nutraceutical compositions or medical food compositions), particularly those having enriched tannic acid populations with superior potency, purity and safety profile. Also provide herein are the tannic acid-containing compositions for use in inhibiting D-amino acid oxidase and/or for treating CNS disorder and obesity disorders including diabetes, hyperglycemia, hyperlipidemia or hypercholesterolemia.
US10105377B2 Compounds and nail polish
Compositions, methods, and kits that deliver a compound, such as 5-fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole, through a keratin substrate are presented.
US10105375B2 Combination of low dose 2-methylene-19-nor-(20S)1α, 25-dihydroxyvitamin D3 and calcimimetics to treat secondary hyperparathyroidism
Disclosed are pharmaceutical compositions and methods of combination therapy that include or utilize low doses of 2-methylene-19-nor-(20S)-1α,25-dihydroxyvitamin D3 and a calcimimetic to treat and/or prevent secondary hyperparathyroidism and/or its accompanying symptoms in a subject having or at risk for developing secondary hyperparathyroidism.
US10105374B2 Controlled release and taste masking oral pharmaceutical compositions
The invention relates to tablet comprising granules dispersed in at least one hydrophilic compound or matrix. The granules contain an active agent, at least one amphiphilic compound and at least one lipophilic compound. The tablet may include a gastro-resistant film coating.
US10105364B2 Ink composition, printed matter and printing method
Provided is an ink composition less likely to cause offset and sticking. Provided is a printed matter and a printing method using such ink composition. The ink composition includes a (meth) acrylic resin and a drying oil, the (meth)acrylic resin: containing at least 40% by weight or more of a structural unit derived from (meth)acryl monomer having a straight-chain alkyl group having 4 or more carbon atoms, branched alkyl group having 4 or more carbon atoms, or cyclic alkyl group having 4 or more carbon atoms (1); having a glass transition temperature of 63° C. to 180° C. (2); and having a weight-average molecular weight of 1000 to 80,000 (3).
US10105363B2 Histone deacetylase inhibitors and compositions and methods of use thereof
Provided are certain histone deacetylase (HDAC) inhibitors of Formula I, compositions thereof, and methods of their use.
US10105362B2 Anti-tumor use of anagrelide and derivatives thereof
The present invention provides an anti-tumor use of Anagrelide and derivatives thereof and, more specifically, the present invention provides the use of Anagrelide and derivatives thereof in the preparation of pharmaceuticals or pharmaceutical compositions for the treatment or inhibition of tumors.
US10105359B2 Tetrahydroisoquinoline derivatives
The present invention relates to tetrahydroisoquinoline derivatives according to formula (I), which are Positive Allosteric Modulators of D1 and accordingly of benefit as pharmaceutical agents for the treatment of diseases in which D1 receptors play a role.
US10105358B2 Niacin formulation
The present invention provides a composition including an amphiphilic compound capable of self-assembling into a liquid crystalline phase; and a niacin compound. In another aspect, the present invention provides a method for the treatment of a disease state comprising administering a therapeutically effective amount of a pharmaceutical composition incorporating that composition.
US10105357B2 Indication of antibiotic drugs for preparation of cancer inhibition pharmaceutical composition
A method for treating a cancer includes administering to a subject in need thereof a pharmaceutical composition containing a therapeutically effective amount of an antibiotic drug or a pharmaceutical acceptable salt thereof. The antibiotic drug is selected from the group consisting of an aminoglycoside antibiotic drug, an anti-fungal antibiotic drug, a Cephalosporin antibiotic drug, a β-propionamide antibiotic drug, a chloramphenicol antibiotic drug, an erythromycin antibiotic drug, a penicillin antibiotic drug, and a tetracycline antibiotic drug.. The cancer is selected from the group consisting of lung cancer, gastrointestinal tract cancer, colorectal cancer, prostate cancer, bladder cancer, cervical cancer, breast cancer, and blood cancer.
US10105355B2 Multi-component crystals of vismodegib and selected co-crystal formers or solvents
The present invention primarily relates to multi-component crystals comprising a compound of formula 1 and a second compound selected from the group consisting of co-crystal formers and solvents. The invention is further related to pharmaceutical compositions comprising such multi-component crystals. Furthermore, the invention relates to processes for preparing said multi-component crystals. The invention also relates to several aspects of using said multi-component crystals or pharmaceutical compositions to treat a disease.
US10105352B2 Detecting and treating growth hormone deficiency
Described herein is a new oral method for using MK-0677 for detecting growth hormone (GH) deficiency (GHD). Also described is a method of treating growth hormone (GH) deficiency (GHD) in children with a functional hypothalamic-pituitary GH axis.
US10105349B2 Organic compounds
The present invention relates to certain PDE2 inhibitory compounds, in free or salt form, pharmaceutical compositions containing such compounds and methods for the treatment of PDE2 mediated disorders.
US10105347B2 Sphaeranthus indicus derived ingredients and their compositions for enhancing physical performance and energy levels
The invention discloses herbal ingredients derived from Sphaeranthus indicus standardized to at least one frullanolide/eudesmanoid sesquiterpene compound and their compositions as natural energy enhancer to provide an onset and steady maintenance of energy and mental alertness in a mammal. The invention further includes the use of ingredients and compositions for food ingredient formulations such as dietary supplement, food ingredient, beverage, snack or energy drink containing the above said herbal ingredient(s) for enhancing physical activity, physical fitness, mental alertness, enhancing energy levels, stamina levels, circulatory health, blood vessel health and for better mental health in warm blooded animal.
US10105342B2 Compositions and methods for treating an infection
The present application relates to compounded compositions, methods of making compounded compositions, and methods of using compounded compositions. For example, disclosed herein are compounded compositions and methods of making compounded compositions comprising one or more anti-infective agents such as mupirocin.
US10105341B2 Treatment for obesity
The present invention relates to a method for treating or preventing obesity in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds. The invention further relates to methods for reducing body weight and/or reducing food intake in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of certain carbamate compounds.
US10105334B2 Particle formulations of all-trans retinoic acid and transforming growth factor beta for the treatment of type 1 diabetes mellitus
Particle formulations are disclosed that include polymeric particles containing a small molecule drug and a high molecular weight therapeutic protein. Methods of making and using the particle formulations also are disclosed. These particle formulations are of use to treat an autoimmune disease, such as diabetes, or an inflammatory disease.
US10105331B2 Substituted aromatic compounds and pharmaceutical compositions for the prevention and treatment of diabetes
The present invention concerns the use of compounds for preventing and/or treating diabetes, for modulating glucose, insulin, and/or triglyceride levels; for reducing blood glucose level; for maintaining or increasing insulin level; for increasing insulin secretion; increasing insulin sensitivity; or decreasing insulin resistance in a subject. These novel uses have been found for compounds represented by Formula I and pharmaceutically acceptable salts. wherein A is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(0)-(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R1 is H, F or OH; R2 is C5 alkyl, C6 alkyl, C5 alkenyl, C6 alkenyl, C(0)-(CH2)n—CH3 or CH(OH)—(CH2)n—CH3 wherein n is 3 or 4; R3 is H, F, OH or CH2Ph; R4 is H, F or OH; Q is 1) (CH2)mC(O)OH wherein m is 1 or 2, 2) CH(CH3)C(O)OH, 3) C(CH3)2C(O)OH, 4) CH(F)—C(O)OH, 5) CF2—C(O)OH, or 6) C(O)—C(O)OH.
US10105329B2 Modulation of regulatory T cells via G-coupled protein receptor 43
Disclosed herein are compositions and methods that are useful for inducing the development of regulatory T cells (Treg). Such compositions and methods are useful for treating inflammatory conditions and in particular inflammatory conditions affecting the gastrointestinal tract of a subject. In certain embodiments, the present inventions generally relate to short chain fatty acids and the discovery that such short chain fatty acids may be used to treat and/or prevent inflammatory conditions by enhancing the size and immune function of a subject's endogenous Treg population.
US10105327B2 Compositions and methods for increasing the metabolic lifetime of dextromethorphane and related pharmacodynamic effects
This disclosure relates to methods administering various compounds in conjunction with dextromethorphan to a human being. Dosage forms, drug delivery systems, and methods related to dextromethorphan or dextrorphan and bupropion, hydroxybupropion, erythrohydroxybupropion, threohydroxybupropion, or a metabolite or prodrug of any of these compounds are also disclosed.
US10105326B2 Pharmaceutical solution comprising dopamine for use in treating parkinson's disease
The present invention is directed to pharmaceutical solution comprising at least dopamine for use in treating Parkinson's disease, wherein said pharmaceutical solution is kept under anaerobic conditions from its formulation to its administration.
US10105322B2 Beta-lactamase formulations and uses thereof
The present invention provides, in part, formulations comprising a beta-lactamase. Particularly, modified-release formulations comprising a beta-lactamase are provided which release a substantial amount of the beta-lactamase in the intestines. Therapeutic uses of the beta-lactamase formulations are also provided.
US10105319B2 Sustained-release formulations of colchicine and methods of using same
Pharmaceutical compositions of colchicine for once-a-day oral administration are provided. The formulations comprise a sustained-release component and an optional immediate-release component, the compositions of which can be selectively adjusted, respectively, to release the active ingredient along a pre-determined or desired release profile. Methods of treating or preventing cardiovascular disease and/or inflammatory disease in mammalian subjects comprising the administration of the novel formulations disclosed herein are also provided.
US10105318B2 Low-dimensional structures of organic and/or inorganic substances and use thereof
The object of the present invention is low-dimensional, primarily 2D folded structures of organic and/or inorganic substances and/or their agglomerates, which have folds and faces of irregular shape and exhibit high local electric field strength generated by surface charges on the said folds, faces and edges, and use thereof: as sorbents of organic particles (molecules, bacteria, viruses, proteins, antigens, endotoxins) and inorganic particles (metal ions, colloids); as an agent with wound healing and antibacterial activity; as an agent for tumor cell growth inhibition.
US10105312B2 Hair growth oil composition
A hair growth oil composition to be applied topically to the human scalp in order to encourage hair growth. The present invention accomplishes these goals through a mixture of ingredients precisely proportioned to achieve a unique chemical composition that brings about maximum results. The ingredients in the composition include coconut oil, emu oil, bhringaraj (eclipta alba), amalaki (emblica officinalis), vitamin E, and pharmaceutically acceptable excipients are described. A method of use is also disclosed.
US10105309B2 Solid powder cosmetic
The present invention provides a solid powder cosmetic exhibiting excellent ease of loosening of the cosmetic, smooth feeling in use, and adhesiveness to the skin and also exhibiting no change in usability in continuous use and having excellent filling and molding properties and drop strength. The invention relates to a solid powder cosmetic containing following components (A), components (B), and components (C); (A) a powder, (B) a (sodium acrylate/sodium acryloyldimethyl taurate) copolymer, and (C) a water-swelling clay mineral.
US10105308B2 Temporary changing the color of hair using pigments, alcohols and zwitterionic polymers
An agent for temporarily changing the color of keratin fibers, in particular human hair, include in an aqueous cosmetic carrier (a) at least one aliphatic and/or aromatic alcohol having 2-8 C atoms (b), at least one color pigment, and (c) at least one zwitterionic polymer, the total weight of the solid matter (d) included in the agent, with respect to the total weight of the agent, being less than 2.5 wt. %.
US10105298B1 Antimicrobial skin cream
Some embodiments of the present disclosure include a cream for treating the skin. The cream may include gray clay kaolin; sodium lauryl ether sulfate; blue tartarzine; sodium chloride; menthol; metabisulfite sodium; gelatin; mineral oil; olive oil; oil of cloves; water; green tea; honey; and aloe vera. The cream may also include talc, apple perfume, vitamin E, vitamin D, vitamin C, vitamin B2, vitamin B5, vitamin H, vitamin B6, and vitamin D. The cream may also include fatty acids.
US10105294B2 Dispersion and method for forming hydrogel
An object is to provide dispersion containing lipid peptide type compound useful as low molecular weight gelator, such as lipid dipeptide and lipid tripeptide, and dissolution accelerator capable of dissolving the lipid peptide type compound at lower temperature and more easily. It is also an object to provide dispersion that can form hydrogel by simpler method and under milder condition (low temperature) and from which gel can be obtained as gel having high thermal stability, and provide method for forming the gel. Dispersion including: a lipid peptide type compound in which peptide portion formed by repetition of at least two or more identical or different amino acids is bonded to lipid portion including C10-24 aliphatic group; dissolution accelerator having, in molecules thereof, hydrophilic portion and hydrophobic portion, the hydrophilic portion having betaine structure; and water; and method for producing hydrogel by use of the dispersion.
US10105293B2 Core-shell particle
There is provided a core-shell particle comprising a polymer conjugate encapsulating an active agent, wherein the polymer conjugate comprises a biocompatible polymer and a polyacidic polymer. There is also provided a process for forming the core-shell particle, a delivery vehicle comprising the core-shell particle and a method for delivering an active agent to a desired site.
US10105292B2 Composition with a continuous oil phase containing at least one lipophilic organic UV-screening agent and hydrophobic silica aerogel particles
The present invention relates to a composition comprising, in a cosmetically acceptable medium, at least one continuous oil phase, characterized in that the oil phase comprises a) at least one non-volatile non-cyclic silicone oil with a viscosity at 25° C. ranging from 4 to 5000 mm2/s, better still from 4 to 1000 mm2/s and even better still from 4 to 200 mm2/s and b) at least one lipophilic organic UV-screening agent; and c) hydrophobic silica aerogel particles with a specific surface area per unit of mass (SM) ranging from 200 to 1500 m2/g, preferably from 600 to 1200 m2/g and better still from 600 to 800 m2/g, and a size, expressed as the volume mean diameter (D[0.5]), of less than 1500 μm, preferably ranging from 1 to 30 μm, more preferentially from 5 to 25 μm, better still from 5 to 20 μm and even better still from 5 to 15 μm. The invention also relates to a cosmetic process for caring for and/or making up human keratin materials, especially bodily or facial skin or the hair, comprising at least the application to the surface of the keratin material of at least one composition as defined previously.
US10105287B2 System and method for remotely monitoring medication compliance using a pillbox with a camera
A system and method for monitoring compliance with medications is disclosed. The system includes a pillbox, a control system that is spaced away from the pillbox, an information transfer system, and a monitoring device. The pillbox includes a lid, a housing base, a camera secured to the pillbox to allow the camera to take pictures for the housing base, and a sound device secured to the housing base. The control system is in communicable connection with the pillbox and the information transfer system. The information transfer system is in communicable connection with the monitoring device. The camera can take pictures or videos and transfer this information to a monitoring device to check compliance. The system configuration and control is moved away from the pillbox and the configuration and control is given to a remote user with a monitoring device.
US10105284B2 Rotating blister dispenser
The present invention relates generally to dispenser packs (10) and in particular rotating blister dispenser packaging structures. A dispenser pack (10) includes at least one circular blister pack (12) including blister cavities (14), wherein the blister cavities (14) are arranged along the circumference of the blister pack (12), and a casing (18) in the form of a closed box, wherein two of the opposite surfaces (A, B) of the casing (18) are square and a corner (C) of the casing (18) is removable for providing an opening (20) in the casing (10). The diameter D of the blister pack (12) is equal to the side lengths L of the two opposite surfaces (A, B) of the casing (18). The blister pack is rotatably mounted inside the casing (18) such that the axis of rotation passes through the center of the blister pack (12). The opening (20) provides access to at least one of the blister cavities (14).
US10105282B1 Dual plumbing system for a hot tub or spa
Systems, apparatus and methods for providing air and water to hot tub jets. The present teachings include jet assemblies, manifold assemblies, and related components, as well as methods of assembling hot tubs involving these components. In some cases, the present teachings describe the use of dual extrusion tubing to route air and water through adjacent, connected fluid conduits. In some cases, the present teachings describe a “press-and-click” method of connecting various components.
US10105281B1 Negative pressure vest
A negative pressure vest includes a housing defining a fixed, minimum interior volume. The housing has a neck opening, a pair of arm openings and a trunk opening. Each of the neck and arm openings includes a sealing member. A one-way check valve communicates between the interior volume and an ambient environment surrounding an exterior of the housing. The one-way check valve is openable at a pressure greater than an ambient atmospheric pressure. A one-way pressure-relief valve communicates between the interior volume and the ambient environment. The one-way intake valve is openable at a predetermined negative pressure. A method of providing negative pressure to the user's thorax is also provided.
US10105279B2 Male sexual dysfunction sufferer-use negative pressure assistance device
Provided is an assistance device comprising a hard sheath that simulates an erect penis and that has on the end thereof an air-bleed hole, and a soft skin that covers the entire hard sheath and that has an air-bleed hole at a position that is slightly offset from the air-bleed hole of the hard sheath, and the device has added thereto a valve function due to the two air-bleed holes.
US10105277B2 Strap for inversion therapy table
A strap for a table having a backrest with a first end and a second end. The strap has a first end and a second end, wherein the first end of the strap is connected to the first end of the table backrest and the second end of the strap is connected to the middle portion of the second end of the table backrest. The strap provides a safety measure in the event the user shifts or slips when using the table. When used on an inversion therapy table, the strap may also enable the user to relieve pressure applied to the ankles and lower legs during inversion therapy. The strap may further include a length adjuster to fit the size of each individual user as well as visual length markers to indicate the adjustment settings for the strap.
US10105276B2 Strap for inversion therapy table
A strap for a table having a backrest with a first end and a second portion. The strap has a first end and a second end, wherein the first end of the strap is connected to the first end of the table backrest and the second end of the strap is connected to the second portion of the table backrest. The strap provides a safety measure in the event the user shifts or slips when using the table. When used on an inversion therapy table, the strap may also enable the user to relieve pressure applied to the ankles and lower legs during inversion therapy. The strap may further include a length adjuster to fit the size of each individual user as well as visual length markers to indicate the adjustment settings for the strap.
US10105272B2 Patient holding hospital unit, patient transportation system and patient transportation and life support system
A patient holding hospital unit is described. The patient holding hospital unit has a supporting surface configured to receive a patient and a life support system. The supporting surface has a container restrained to the supporting surface that contains an anesthesia machine, reservoirs and related ducts, perfusion devices, an automatic control system, a power supply unit, a power supply line. The container also has dispensing valves arranged on an external surface of the container together with a control interface and the supply valves and electric connector of the power supply line are arranged at a connecting member adapted to be mounted to a base member configured to supply gases under pressure to the reservoirs and power to the control system.
US10105268B2 Nonwoven material having discrete three-dimensional deformations with differential opacity regions
Nonwoven materials having a first region and a plurality of discrete integral second regions that are in the form of three-dimensional deformations forming protrusions that extend outward from the first surface of the nonwoven material and wide base openings adjacent to the second surface of the nonwoven material are disclosed. The nonwoven materials include at least two layers that are each formed of a plurality of fibers. The first region has a first light transmission value and the second regions have a second light transmission value.
US10105266B2 Tampon assembly having a shaped pledget
The present invention provides a tampon applicator assembly having an applicator barrel with an insertion tip with a maximum of three petals. Additionally, the tampon applicator assembly can be provided with a tapered insertion tip. A shaped pledget can be housed in the applicator barrel, which provides support to the petals.
US10105264B2 Ear cleaning device
An ear cleaning device for more facile and healthier ear wax removal includes a tube and a pair of cups. Each cup is coupled singly to and extends from a respective opposing end of the tube. Each cup comprises an annular wall that extends between a bottom and a top to define an internal space. The bottom is positioned adjacent to the tube. The top is open. The tube is configured to be grasped by the digits of a hand of a user. The cups are configured to insert into an ear of the user. Debris, such as wax, that positioned on a wall of the ear canal of the ear is collected upon an external surface of a cup as the cup is rotated within the ear canal. Debris that is positioned proximate to the wall of the ear canal is collected in the internal space of the cup.
US10105249B2 Apparatus and method for deploying an implantable device within the body
The present invention provides systems and methods for deploying implantable devices within the body. The delivery and deployment systems include at least one catheter or an assembly of catheters for selectively positioning the lumens of the implant to within target vessels. Various deployment and attachment mechanisms are provided for selectively deploying the implants.
US10105247B2 Thumbwheel actuated vascular intervention device delivery system
A vascular intervention device delivery system, such as for implanting a self expanding stent, includes a thumbwheel rotatably mounted in a handle. A catheter has a proximal end attached to the handle and a distal carrier segment for mounting a stent thereon. A retractable sheath is movable to a position retracted proximally to uncover the distal carrier segment. A pull with a curved cross section extends between the thumbwheel and the retractable sheath. An idler wheel with a perimeter notch is rotatably mounted in the handle proximal to the thumbwheel. A pin is movably in the handle between a first position received in the perimeter notch to block rotation of the idler wheel, and a second position outside of the perimeter notch to permit rotation of the idler wheel. The pull wraps around the idler wheel to return in a direction for being wound onto a spool of the thumbwheel.
US10105243B2 Ankle-foot prosthesis for automatic adaptation to sloped walking surfaces
An ankle-foot prosthesis includes a foot plate, an ankle frame attached to the foot plate, a yoke pivotally connected to the ankle frame and including a member for attaching to a leg, a damper having a first end connected to the yoke and a second end connected to the ankle frame, and a control mechanism for switching the damper between low and high settings.
US10105240B2 Spinal implant and method for fabricating the same
A spinal implant is provided that includes a body extending in direction at least substantially along a body axis, between a first end portion and a second end portion. The spinal implant also includes a first bearing surface disposed relative to the first end portion, and defining a first relief pattern that is configured to inhibit movement of the spinal implant relative to one or more vertebrae in at least substantially all directions. A method for manufacturing the spinal implant involves use of selective laser sintering.
US10105236B2 Arcuate fixation member
Arcuate fixation members with varying configurations and/or features are provided, along with additional components for use therewith in provided fixation systems and intervertebral implant systems. The arcuate fixation members may be of varying lengths, cross sectional geometries, and/or cross sectional areas, and may be configured with various features such as heads configured to accept other fixation system components, tabs to allow arcuate fixation member-in-arcuate fixation member or fixation anchor-in-arcuate fixation member configurations. Applications of fixation systems and intervertebral implants systems utilizing arcuate fixation members are particularly suitable when a linear line-of-approach for delivering fixation members is undesirable.
US10105235B2 Intervertebral cage and method of treating vertebrae with an intervertebral cage
The present disclosure provides an intervertebral cage including superior and inferior members each including an engagement surface for engaging a corresponding vertebrae. The intervertebral cage also includes a posterior member that extends between a posterior end of the superior and inferior members and spaces them from each other in a superior-inferior direction. The superior and inferior members extend in a posterior-to-anterior direction from the posterior member and define anterior free ends to form a substantially open anterior end between the superior member and the inferior member in a posterior-anterior direction. The engagement surfaces of the superior and inferior members substantially diverge from each other in the superior-inferior direction along the posterior-to-anterior direction. The superior and inferior members each include first apertures extending therethrough in the superior-inferior direction that define a pathway through the intervertebral cage in the superior-inferior direction.
US10105234B2 Spinal implant system and methods of use
The spinal implant includes a tissue barrier. A first member extends in a transverse orientation from the tissue barrier and is connectable with vertebral tissue adjacent a lamina. A second member is spaced from the first member and extends in a transverse orientation from the tissue barrier. The second member is connectable with vertebral tissue adjacent a lamina. At least one of the members includes an end that is disposable about at least a portion of the vertebral tissue. Systems and methods of use are disclosed.
US10105233B2 Anterior prosthetic spinal disc replacement
The present invention relates generally to a prosthetic spinal disc for replacing a damaged disc between two vertebrae of a spine. The present invention also relates to a method for implanting a prosthetic spinal disc via anterior or anterior lateral implantation. Other surgical approaches for implanting the prosthetic disc may also be used.
US10105229B2 Methods for bone and cartilage reconstruction
The aim of the invention is to restore the mobility of an articular end (2) of a bone (3) of a patient by means of a reconstruction implant. This implant (1), which permits reconstruction both of bone and of cartilage, comprises a grated framework (10) and a sheet (20) made of a biological tissue material, this sheet firmly covering one face (11) of the framework, while the opposite face (12) is designed to be pressed rigidly against, and firmly joined to, the end of the bone.
US10105221B2 Method and apparatus for percutaneous delivery and deployment of a cardiovascular prosthesis
Catheter apparatuses and methods are provided for repairing heart valves, particularly mitral valves. The method includes providing a catheter having an elongate, flexible body, with a proximal end and a distal end. The distal end can be transluminally advanced from the left atrium through the mitral valve and along the left ventricular outflow tract into the ascending aorta. A valve repair device is deployed to permanently connect leaflets at a mid-section of a mitral valve while permitting medial and lateral portions of the natural leaflets to open and close. The valve repair device detachably connects the distal and proximal ends of the catheter.
US10105218B2 Aortic valve stent graft
An implantable endoluminal prosthesis for replacing a damaged aortic valve is provided. In one embodiment, the prosthesis includes a balloon-expandable stent, a tubular conduit that extends into the ascending aorta, and a self-expanding stent. The tubular conduit extends across the balloon-expandable stent. The tubular conduit includes an artificial valve. The self-expanding stent extends across the tubular conduit into the ascending aorta. The balloon-expandable stent, the tubular conduit, and the self-expanding stent are coupled to provide unidirectional flow of fluid into the aorta and further into the coronary arteries. Also provided is a method for implanting the endoluminal prosthesis.
US10105217B2 Valve for short time replacement, for taking over the function of and/or for temporary or partial support of a native valve in a heart and a method for delivery therefor
Disclosed is a valve (502) for short time replacement, for taking over the function of and/or for temporary support of a native valve in a heart, the valve being positioned through the native valve upon implantation, the valve comprising an at least partially collapsible and/or at least partially expandable tube (602) and a flange (708). The valve allows for fast and easy replacement of a native valve, and more time for medical personnel to make decisions, prepare and/or perform surgery/medical intervention. Thus, the valve may provide for an improved quality of surgery/medical intervention.
US10105214B2 Accommodating intraocular lens providing progressive power change
An accommodating intraocular lens for providing a range of accommodative vision includes a deformable optic. The deformable optic includes a plurality of layers that have a progressively increasing hardness and/or refractive index characteristic from the outermost layer to the innermost layer to provide a range of accommodative power.
US10105213B2 Prosthetic implant delivery device and method
A prosthetic implant transfer device is provided that may be used to insert a prosthetic implant through a surgical opening. In some embodiments, the device may comprise a flexible sheet of material that may be formed into an elongated hollow structure. The flexible sheet of material includes a plurality of fasteners that may be selected and engaged to define a desired size distal opening.
US10105210B2 Tendon repair implant and method of arthroscopic implantation
A tendon repair implant for treatment of a partial thickness tear in the supraspinatus tendon of the shoulder is provided. The implant may incorporate features of rapid deployment and fixation by arthroscopic surgery that compliment current procedures; tensile properties that result in desired sharing of anatomical load between the implant and native tendon during rehabilitation; selected porosity and longitudinal pathways for tissue in-growth; sufficient cyclic straining of the implant in the longitudinal direction to promote remodeling of new tissue to tendon-like tissue; and, may include a bioresorbable construction to provide transfer of additional load to new tendon-like tissue and native tendon over time.
US10105207B2 Porous and nonporous materials for tissue grafting and repair
Implants having improved mechanical properties and/or degradation profiles, kits including such implants, and methods of producing and using the same.
US10105196B2 Modeling and manufacturing the superstructure for a denture
The present invention relates to a system and a method for providing a model of a superstructure joining a denture and a corresponding dental arch, the method comprising the steps of: obtaining a first 3D representation of at least a part of a preliminary model of the denture, obtaining a second 3D representation of at least a part of the dental arch comprising dental implants, and generating a model of a superstructure based on the first 3D representation, the second 3D representation, dental implant positions and dental implant orientations.
US10105191B2 Marking tissue surfaces for treatment of lesions by electrical nanopulses
This disclosure relates to an in vivo treatment of a skin lesion of a mammal comprising application of electrical energy to the skin lesion in a form of electrical pulses. At least one electrical pulse is applied. The pulse duration may be at least 1 nanosecond at the full-width-half-maximum. Surface of a tissue surrounding the skin lesion may be marked to guide the device to deliver the electric pulses at substantially precise locations on the lesion surface. This treatment may prevent at least growth of the lesion.
US10105184B2 Laser tissue ablation system
Embodiments of the invention are directed to a laser ablation system. In one embodiment, the laser ablation system comprises a shaft, a balloon, a laser fiber and a viewing fiber. The shaft has a proximal end and a distal end. The balloon is attached to the distal end of the shaft, a portion of which is within the balloon. The laser fiber has a distal end comprising a light dispenser that is configured to deliver laser light through the balloon. The viewing fiber is configured to image an interior balloon. In accordance with another embodiment, the laser ablation system comprises a shaft, a balloon and a laser fiber. The shaft has a proximal end and a distal end. The balloon is attached to the distal end of the shaft, which is within the balloon. The balloon includes an inflated state, in which the balloon is shaped to conform to a cavity of a patient. The laser fiber has a distal end comprising light dispenser that is configured to deliver laser light through the balloon.
US10105183B2 Laser shaving
A device configured to cut hair using laser light includes a handle portion and a shaving portion. The handle portion includes a battery and a laser light source. The laser light source is coupled to and configured to receive power from the battery. The laser light source is also configured to generate laser light having a wavelength selected to target a predetermined chromophore to effectively cut a hair shaft. The shaving portion includes a support and a single fiber optic supported by the support. The fiber optic has a proximal end, a distal end, an outer wall, and a cutting region positioned towards the distal end and extending along a portion of the side wall. The fiber optic is positioned to receive the laser light from the laser light source at the proximal end, conduct the laser light from the proximal end toward the distal end, and emit the light out of the cutting region and toward hair when the cutting region is brought in contact with the hair.
US10105182B2 Laser shaving
A device configured to cut hair using laser light includes a handle portion and a shaving portion. The handle portion includes a battery and a laser light source. The laser light source is coupled to and configured to receive power from the battery. The laser light source is also configured to generate laser light having a wavelength selected to target a predetermined chromophore to effectively cut a hair shaft. The shaving portion includes a support and a single fiber optic supported by the support. The fiber optic has a proximal end, a distal end, an outer wall, and a cutting region positioned towards the distal end and extending along a portion of the side wall. The fiber optic is positioned to receive the laser light from the laser light source at the proximal end, conduct the laser light from the proximal end toward the distal end, and emit the light out of the cutting region and toward hair when the cutting region is brought in contact with the hair.
US10105181B2 Microwave energy-delivery device and system
An ablation system including an image database storing a plurality of computed tomography (CT) images of a luminal network and a navigation system enabling, in combination with an endoscope and the CT images, navigation of a locatable guide and an extended working channel to a point of interest. The system further includes one or more fiducial markers, placed in proximity to the point of interest and a percutaneous microwave ablation device for applying energy to the point of interest.
US10105180B2 Methods and apparatus for intravascularly-induced neuromodulation
Methods and apparatus are provided for intravascularly-induced neuromodulation using a pulsed electric field, e.g., to effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, changes in cytokine upregulation, etc., in target neural fibers. In some embodiments, the intravascular PEF system comprises a catheter having a pair of bipolar electrodes for delivering the PEF, with a first electrode positioned on a first side of an impedance-altering element and a second electrode positioned on an opposing side of the impedance-altering element. A length of the electrodes, as well as a separation distance between the first and second electrodes, may be specified such that, with the impedance-altering element deployed in a manner that locally increases impedance within a patient's vessel, e.g., with the impedance-altering element deployed into contact with the vessel wall at a treatment site within the patient's vasculature, a magnitude of applied voltage delivered across the bipolar electrodes necessary to achieve desired neuromodulation is reduced relative to an intravascular PEF system having similarly spaced electrodes but no (or an undeployed) impedance-altering element. In a preferred embodiment, the impedance-altering element comprises an inflatable balloon configured to locally increase impedance within a patient's vasculature. The methods and apparatus of the present invention may be used to modulate a neural fiber that contributes to renal function.
US10105179B2 Catheter sensing and irrigating
Ablation systems of the present disclosure facilitate the safe formation of wide and deep lesions. For example, ablation systems of the present disclosure can allow for the flow of irrigation fluid and blood through an expandable ablation electrode, resulting in efficient and effective cooling of the ablation electrode as the ablation electrode delivers energy at a treatment site of the patient. Additionally, or alternatively, ablation systems of the present disclosure can include a deformable ablation electrode and a plurality of sensors that, in cooperation, sense the deformation of the ablation electrode, to provide a robust indication of the extent and direction of contact between the ablation electrode and tissue at a treatment site.
US10105175B2 Electrosurgical device and methods
An electrosurgical bipolar probe with internal cooling for use in systems and methods for lesioning in bone and other tissue is disclosed. The bipolar probe includes tubular electrodes configured such that the inner surface of the electrodes are cooled, directly or indirectly, while keeping the electrodes electrically isolated. An exemplary disclosed method of using a bipolar probe having an active tip having at least two electrodes for delivering energy includes the steps of: advancing the active tip into a bone tissue; delivering energy substantially between the electrodes in a bipolar manner; and supplying cooling fluid to the active tip for internal cooling of the electrodes. Some versions of the method further include the steps of monitoring the temperature of tissue to which the energy is being delivered; and controlling the delivery of energy in suspense to the temperature of the tissue.
US10105171B2 Method for balloon-assisted augmentation and fusion of adjacent vertebral bodies
A vertebral augmentation system and methods for vertebral augmentation and/or fusion using same are provided. In certain embodiments, a pre-curved stylet or needle with an overlying delivery tube may be used to target a site within a bone structure, facilitating direction thereto of an expandable member useful for creating a cavity that may receive curable material to restore bone height, to reinforce the bone structure, and/or to fuse two, three, or more adjacent vertebrae. An expandable member such as, for example, a balloon can be used to create a plurality of voids by displacing bone material, where the voids can be filled with curable material to augment the vertebrae and intervening space can be filled to fuse those adjacent vertebrae.
US10105170B2 Sternal closure assembly
A sternal closure assembly for securing first and second lateral halves of a sternum. The assembly includes a first sliding body having a female portion and a second sliding body having a male portion, the male portion being telescopically mateable with the female portion. The male portion is capable of being fully introduced into the female portion only upon there being an elastic deformation of at least a part of at least one of the male and female portions, the male and female portions configured such that when the second body is mated with the first body the elastic deformation results in a forceful engagement between the male and female portions and also a forceful engagement between a first set of non-deforming teeth extending upward from an interconnecting bridge member of the first sliding body and a second set of non-deforming teeth extending upward from an interconnecting bridge member of the second sliding body.
US10105167B2 System and method for altering rotational alignment of bone sections
A rotational correction system includes an implant having first and second sections, the implant having a rotatable permanent magnet disposed in a housing of the first section, the rotatable permanent magnet mechanically connected to a nut operatively coupled to the second section. A keyed portion is interposed between the nut and one or more non-linear grooves disposed on an inner surface of the housing. An external adjustment device having at least one rotatable magnet configured to rotate the rotatable permanent magnet of the implant is part of the system. Rotation of the rotatable permanent magnet of the implant in a first direction effectuates a clockwise change in the rotational orientation of the first section relative to the second section and rotation of the rotatable permanent magnet of the implant in a second direction effectuates a counter-clockwise change in the rotational orientation of the first section relative to the second section.
US10105165B2 Instrument for holding and inserting a bone anchor
An instrument for holding and inserting a bone anchor into a bone is provided, where the bone anchor includes a shank for anchoring in the bone and a head. The instrument includes a holding member for holding the head of the bone anchor and has a plurality of arms configured to at least partially encompass the head, where the arms include an inner surface forming a seat for the head. The instrument also includes a drive shaft for engaging the head of the bone anchor and defining a longitudinal axis of the instrument. The instrument further includes a displacement member configured to act on the holding member. The holding member can assume a first configuration in which it is configured to permit the head to enter the seat and a second configuration in which it is configured to hold the head in the seat.
US10105164B2 Facet fixation targeting guide
A facet fixation device formed from an anchor screw and a collet or facet screw that is secured to adjacent pedicles. The anchor screw has an aperture for receipt of a first end of a guide wire or polyaxial based facet screw. The collet includes a unidirectional attachment mechanism wherein a wire can be drawn to a desired position to fix the distance between the anchor screw and the collet. Excess wire can then be removed.
US10105155B2 Endoscopic instrument
An endoscopic instrument having a proximal end, a distal end, a longitudinal direction, an end effector with first and second end effector parts, a bearing element at the distal end, on which bearing element the first and second end effector parts are arranged, and first, second and third thrust elements, wherein the thrust elements each extend along the longitudinal direction and are displaceable relative to one another, wherein the first thrust element is articulately coupled to the first end effector part, the second thrust element is articulately coupled to the second end effector part, the third thrust element is articulately coupled to the first end effector part and the second end effector part, and wherein the first and second end effector parts have bearing surfaces, and the bearing surfaces are each held slidably on the bearing element.
US10105149B2 On-board tool tracking system and methods of computer assisted surgery
A number of improvements are provided relating to computer aided surgery utilizing an on tool tracking system. The various improvements relate generally to both the methods used during computer aided surgery and the devices used during such procedures. Other improvements relate to the structure of the tools used during a procedure and how the tools can be controlled using the OTT device. Still other improvements relate to methods of providing feedback during a procedure to improve either the efficiency or quality, or both, for a procedure including the rate of and type of data processed depending upon a CAS mode.
US10105147B2 Surgical bur with a head having plural flutes, the flutes shaped so that, at the equator, the head has a shape that is not circular
A bur with features that minimize the application of substantially identical forces to the tissue against which the bur is applied. One of these features is the arrangement of the flutes so that one pair of flutes projects outwardly from the tip at an acute angle that is greater than the angle at which the other flutes project outwardly from tip. Consequently at the equator of the bur head, the location along the bur head where the bur head has a maximum diameter, the flutes define a perimeter that is non-circular in shape.
US10105142B2 Surgical stapler with plurality of cutting elements
An apparatus comprises a body, a shaft assembly, an end effector, a cartridge, and a staple driver actuator. The end effector is operable to manipulate tissue. The end effector comprises a lower jaw, a pivotable anvil, and a translating cutter. The translating cutter is operable to translate relative to the lower jaw and the anvil when the anvil is pivoted toward the lower jaw to manipulate tissue. The cartridge is insertable into the lower jaw and includes a plurality of staples. The staple driver actuator is disposed within the cartridge. The staple driver actuator comprises a secondary cutting element. The translating cutter of the end effector is operable to drive the staple driver actuator distally to staple and cut tissue substantially simultaneously.
US10105141B2 Tissue apposition clip application methods
Surgical methods for closing a gastrotomy. The surgical method for closing an opening in an organ wall comprises positioning a distal end portion of a steerable overtube adjacent a portion of the organ wall through which the opening extends. The surgical method further comprises inserting a flexible clip magazine into the steerable overtube. The surgical method comprises grasping tissue through which the opening extends and drawing a portion of the grasped tissue into a clamping position between upper and lower clip arms of a distal-most tissue apposition clip supported within a distal end of the clip magazine. The surgical method further comprises advancing the distal-most tissue apposition clip onto the portion of grasped tissue.
US10105137B2 Surgical stapling instruments including a cartridge having multiple staples sizes
A surgical stapling apparatus includes a staple cartridge and an anvil member. The staple cartridge includes a plurality of surgical fasteners disposed in rows of retention slots. The staple cartridge may have an annular or linear configuration of retention slots. The tissue contacting surface of the staple cartridge may be tapered or stepped. The anvil member has a tissue contacting surface that includes a number of pockets arranged for substantially aligning with the retention slots. In addition, the tissue contacting surface of the anvil member may complement the tissue contacting surface of the staple cartridge.
US10105130B2 Remotely adjustable tissue displacement device
The invention relates to an apparatus for displacing tissue within the body, wherein the apparatus includes two or more attachment members selectively displaceable with respect to each other via a driving member. The driving member preferably is rotatable and is caused to rotate by a magnetic actuator that can be activated by a magnetic field from outside the body.
US10105126B2 Self-articulating joint for a minimally invasive surgical apparatus
A self-articulating joint is disclosed for a minimally invasive surgical apparatus. The self-articulating joint has a first elbow component pivotably coupled to a second elbow component, wherein the first and second elbow components are biased to form a non-linear angle relative to each other. The self-articulating joint also has an elbow latch configured to releasably hold the first and second elbow components at a substantially fixed non-linear operating angle.
US10105117B2 Compensation for heart movement using coronary sinus catheter images
Cardiac catheterization is carried out by introducing a catheter into the coronary sinus, acquiring a first set of 2-dimensional images of the catheter, thereafter acquiring a second set of 2-dimensional images of the catheter, and creating respective 2-dimensional models of the catheter in synchronized frames of the first set and the second set. The 2-dimensional models include respective tracked 2-dimensional paths of the catheter. The first and second sets are synchronized by identifying frames that are in respective phases of the cardiorespiratory cycle. First and second 3-dimensional models of the catheter are constructed from the synchronized frames, and geometrically transformed to minimize a distance function between the two models.
US10105115B2 Method and system for processing medical image datasets
A method and system are provided for creating and simultaneously displaying medical scan images, from each of first (780) and second (530) medical scan datasets, obtained by scanning a 3-dimensional (3-D) object with different scanning modalities. A first image (410) is derived from the first (780) dataset, the first image (410) lying in a first plane corresponding to an acquisition plane of the first (780) dataset. A second image (420) is obtained from the second dataset (530), the second image also lying in the first plane. The second image may be obtained by re-slicing the second data set. One or both medical scan datasets may be multivolume datasets. The invention may improve viewing resolution and/or speed, when viewing a multi-series MRI scan together with a CT and/or a PET scan.
US10105113B2 Rotating-grating cone beam CT
Disclosed is a rotating-grating cone beam CT imaging apparatus. This imaging apparatus is composed of a frame, a frame angle sensor, an X-ray source equipped with a rotating grating, a flat panel detector, a main controller and an image reconstruction workstation. Like a general cone beam CT imaging apparatus, this imaging apparatus also adopts an open structure. But unlike the general cone beam CT imaging apparatus, the rotating grating limits X-rays emitted from the X-ray source to a plurality of narrow-angle cone beams or sector beams. In the process that the X-ray source and the detector rotate around an imaging object, projection images of the narrow-angle cone beams or sector beams on the flat panel detector move back and forth continually through the rotation of the rotating grating, so as to acquire projection information about the imaging object in an entire scanning region. Finally, the projection information is reconstructed into a volume image in the image reconstruction workstation. In this manner of variable-focus scanning, the present invention not only can reserve the advantage of the open structure of the cone beam CT imaging apparatus, but also obtains the advantage that a sector beam CT imaging apparatus can restrain scattered photons so as to generate a high-quality image.
US10105110B2 Selecting scanning voltages for dual energy CT scanning
A method and apparatus for selecting high and low energy scanning voltages for a dual energy CT scanner are provided. The method may comprise: setting a criterion of selection for selecting high and low energy scanning voltages; generating combinations of high and low energy scanning voltages according to all scanning voltages supported by a dual energy CT scanner, wherein each of the combinations may comprise a high energy scanning voltage and a low energy scanning voltage; and selecting a combination of high and low energy scanning voltages from the generated combinations of high and low energy scanning voltages based on the criterion of selection.
US10105100B2 Display on a bandage-type monitoring device
A body-mountable device includes a flexible substrate configured for mounting to a skin surface. The flexible substrate is configured to be adhered or otherwise mounted to the skin in a manner that minimally impacts activities of the body. The device includes a flexible display configured to provide indications to a user, e.g., indications of sensor readings, medical alerts, or operational states of the device. The display could be operated on a very low power budget, e.g., the display could be operated intermittently. In some examples, the display could include an e-paper display or similar low power display elements. In some examples, elements of the display, e.g., electrodes of a multi-segment display, could be formed on the flexible substrate such that additional elements of the display, e.g., a layer of display medium and a layer of transparent conductor, could be adhered or otherwise attached to the formed elements.
US10105099B2 Nasal and oral patient interfaces
A patient interface for communicating fluids to and/or from a patient's nasal cavity and/or oral cavity is disclosed. In addition, a patient interface for fluid and physiological function monitoring proximate to the patient's nasal cavity and/or oral cavity is disclosed. An apnea monitor and a method for monitoring apnea are also disclosed.
US10105097B2 Wearable items providing physiological, environmental and situational parameter monitoring
A garment and/or garment system with health-monitoring (e.g., cardiovascular monitoring) capability, substantially as shown in and/or described in connection with at least one of the figures, as set forth more completely in the claims.
US10105096B2 Biological observation apparatus
Provided is a biological observation apparatus including irradiating portions that radiate illumination light onto biological tissue, an imaging portion that, of reflected light reflected at the biological tissue due to the illumination light radiated by the irradiating portions, captures reflected light in a wavelength band in which an absorption characteristic of β-carotene is greater than an absorption characteristic of hemoglobin, thus acquiring a reflected-light image, and a display portion that displays the reflected-light image acquired by the imaging portion.
US10105094B2 Supplementary device for a manually operable injection device
The present invention relates to a supplementary device a supplementary device for a manually operable injection device. The supplementary device has a body defining a passage through which an injection device is slidable, and a securing unit to secure the body to the injection device in the specific position when the injection device is received through the passage.
US10105092B2 Detecting sleeping disorders
Introduced are methods and systems for monitoring a person's sleeping patterns, and detecting episodes of sleeping disorders such as snoring and sleep apnea. In one embodiment, a sensor strip attached to the mattress monitors the user's breathing, and detects signature frequencies corresponding to snoring and sleep apnea. Once a sleeping disorder is detected, a notification can be sent to a device associated with the user, or the user's bed can be automatically adjusted to alleviate the sleeping disorder.
US10105090B2 Method for representations of network-dependent features of the hemoglobin signal in living tissues for detection of breast cancer and other applications
A non-invasive method of detecting anomalous tissue, such as cancerous or injured tissue, in a patient. At least two hemoglobin signal components of hemoglobin levels in at least one segment of tissue of the patient are non-invasively measured over time. Time varying changes of at least a first of the hemoglobin signal components are measured with respect to at least time varying changes of a second of the hemoglobin signal components. A co-varying coordinate system of the time varying changes is generated. Any anomalous tissue in the measured segment of tissue is detected from a signature of the measured segment of tissue in the co-varying coordinate system which differs from a signature of non-anomalous tissue in the co-varying coordinate system. Preferably, five hemoglobin signal components are measured: oxyHb, deoxyHb, total Hb (totalHb=oxyHb+deoxy Hb), Hb oxygen saturation (HbO2Sat=(oxyHb/totalHb)*100), and tissue-hemoglobin oxygen exchange HbO2Exc (deoxyHb−oxyHb).
US10105081B2 Implantable sensor
A sensor for sensing a substance such as for example glucose. The sensor is implantable in the body of a living creature. The sensor has a photonic integrated circuit, e.g. silicon-photonics integrated circuit, for spectrally processing radiation interacting with the sample. A continuous monitoring system can also include such a sensor.
US10105080B1 Interstitial fluid sampling above microneedle array
Devices are provided that include a plurality of microneedles that penetrate skin and that receive interstitial fluid from the skin tissue. The microneedles are further configured to direct the received interstitial fluid to nanosensors configured to change an optical property based on interaction with an analyte in the received interstitial fluid, allowing optical detection of the analyte. Direction of the received interstitial fluid to the nanosensors can be facilitated by a pump configured to control the flow rate of the interstitial fluid through the microneedles. Such devices could be configured to detect the analyte independently or in combination with a reader device configured to be periodically mounted to the devices and to detect the analyte. Further, such devices can include delivery systems configured to transdermally deliver a drug or other substance into or through the skin in response to a detected concentration, presence, or other property of the analyte.
US10105079B2 Lancing device
A lancing device includes a lancet body (14) of elongate form and having a sharp tip (16) at the forward end thereof; a drive spring (26) for imparting generally longitudinal movement to the lancet body, and a housing (10) receiving the lancet body and having an aperture (22) in the forward end thereof through which the sharp tip (16) of the lancet body projects in use when the device is fired. The device includes elements (28, 30, 32) for controlling movement of the lancet body (14) to cause the tip of the lancet to execute a lateral movement when it projects from the aperture.
US10105072B2 Measurement device for measuring bio-impedance and/or a bio-potential of a human or animal body
Measurement device for measuring a bio-impedance and/or a bio-potential of a human or animal body and adapted to be worn on the body, including: at least two electrode sensors. Each of the at least two electrode sensors includes a first electrical contact configured to be in electrical contact with the skin of the body when the system is worn, and a second electrical contact. A single electrical connector electrically connects the at least two electrode sensors with each other via the second electrical contact. An active device is configured to cooperate with a subset of the at least two electrode sensors such that the potential of the electrical connector is substantially equal to a projected potential determined from the potential of the first electrical contact of each electrode sensor of the subset when the measurement device is worn.
US10105069B2 Induction heating applications
A system and method for inductive heating applications includes positioning one or more inductive heating elements in a location, delivering electromagnetic radiation, by a radiation source, to heat at least a portion of the one or more inductive heating elements, and detecting, by a detector, the heat generated by the one or more inductive heating elements. The system and method also include controlling, by a processing unit, a condition based on the detected heat.
US10105067B2 Method of detecting portal and/or hepatic pressure and a portal hypertension monitoring system
The devices and methods generally relate to vibratable sensors for measuring ambient fluid pressure, in particular implantable sensors. The devices and methods are particularly well-suited to implantation within the body of a living animal or human to monitor physiological conditions, such as portal and/or hepatic venous blood pressure, and allow frequent, remote interrogation of venous pressure using the resonance frequency of an implanted sensor. The sensor devices are relatively small compared to conventional devices for measuring fluid pressure and can be implanted in the porto-hepatic venous system, whereas conventional devices are too large. The small size of the device is accomplished by using a thick sensor membrane, compared to conventional devices, and by limiting the size of additional elements of the device relative to the size of the sensor membrane. The thicker sensor member also obviates the need for multiple sensor arrays and maintains the accuracy and robustness of the sensor device. A data capture, processing, and display system provides a pressure measurement reading, and is particularly well-suited for detecting portal hypertension in patients with liver disorders.
US10105066B2 Method and apparatus for controlling alarms
Methods, apparatuses and systems for controlling an alarm are set forth herein for reminding a user with assurance of sleep quality. The method includes receiving sleep information, determining a sleep status, determining whether duration of the sleep status reaches a pre-determined duration threshold, and based on a determination that the duration of the sleep status reaches the pre-determined duration threshold, outputting alarming information.
US10105064B2 Physiological sensor delivery device and method
An intravascular sensor delivery device for measuring a physiological parameter of a patient, such as blood pressure, within a vascular structure or passage. In some embodiments, the device can be used to measure the pressure gradient across a stenotic lesion or heart valve. For example, such a device may be used to measure fractional flow reserve (FFR) across a stenotic lesion in order to assess the severity of the lesion. The sensor delivery device has a distal sleeve configured to pass or slide over a standard medical guidewire. Some distance back from the sensor and distal sleeve, the device separates from the guidewire to permit independent control of the sensor delivery device and the guidewire. The sensor delivery device can be sized to pass over different sizes of guidewires to enable usage in coronary and peripheral arteries, for example.
US10105061B2 Subject information obtaining apparatus
A long period of time is required to complete measurement performed by a subject information obtaining apparatus. Accordingly, a subject information obtaining apparatus includes a receiver including a plurality of conversion elements which receive acoustic waves and output reception signals and a supporting member including the conversion elements disposed therein, a movement mechanism configured to move the receiver, and a controller configured to input a driving signal to the movement mechanism. The conversion elements are disposed in the supporting member such that directional axes of a number of the conversion elements are converged. The controller controls the movement mechanism so that a center position of a scanning trajectory of the receiver is changed.
US10105059B2 System configured for measuring physiological parameters
A wearable device for measuring physiological parameters includes a light source having a plurality of semiconductor light emitting diodes (LEDs) each configured to generate an output optical beam, wherein at least a portion of the one or more optical beam wavelengths is a near-infrared wavelength. The light source is configured to increase signal-to-noise ratio by increasing light intensity for at least one of the LEDs and by increasing a pulse rate of at least one of the LEDs. A lens is configured to receive the output optical beam and to deliver a lens output beam to tissue. A detection system generates an output signal in response to the lens output beam reflected from the tissue, wherein the detection system is configured to be synchronized to the light source, and is located a different distance from a first one of the LEDs than a second one of the LEDs.
US10105058B2 Orbital angular momentum and fluorescence- based microendoscope spectroscopy for cancer diagnosis
An apparatus for performing an endoscopic procedure for detecting cancerous tissue includes a detection probe for detecting the cancerous tissue. The detection probe includes a first fiber for emitting an ultraviolet light beam having an orthogonal function applied thereto and a second fiber for receiving emissions from tissues responsive to the ultraviolet light beam emitted for the first fiber. An ultraviolet emission source generates the ultraviolet light beam. Orthogonal function circuitry applies the orthogonal function twist to the ultraviolet light beam. Detection circuitry detects fluorescence and orthogonal function within the emissions from the tissues received over the second fiber.
US10105055B2 Systems and methods for communicating data
An external medical device including monitoring circuitry and communication circuitry. The monitoring circuitry monitors a cardiac condition of a patient using the external medical device. For example, the communication circuitry initiates a communication link with a remote location. The remote location can be selected based on data associated with at least one of the external medical device and the patient using the external medical device. In some examples, supporting data can be transmitted to the remote location.
US10105051B2 System and method for a portable eye examination camera
A system and method for a portable eye examination camera is described herein. The system and method may include: a light source disposed within said portable camera at a set distance away from an eye of a patient; a first lens within said portable camera for focusing the light from said light source onto a retina of the eye and providing a wide field retinal image; a second lens for receiving said retinal image and causing a magnification of said retinal image; and a digital camera within a mobile computing device for recording said retinal image.
US10105045B2 Optical diagnosis using measurement sequence
Devices, systems, and methods that facilitate optical analysis, particularly for the diagnosis and treatment of refractive errors of the eye. An optical diagnostic method for an eye includes obtaining a sequence of aberration measurements of the eye, identifying an outlier aberration measurement of the sequence of aberration measurements, and excluding the outlier aberration measurement from the sequence of aberration measurements to produce a qualified sequence of aberration measurements. The sequence of aberrations measurements can be obtained by using a wavefront sensor. An optical correction for the eye can be formulated in response to the qualified sequence of aberration measurements.
US10105041B2 Light guiding optical system and endoscopic apparatus having the same
A light guiding optical system includes a light guide configured to guide light from an entrance end to an exit end by internally reflecting the light a plurality of times, and an optical unit configured to condense the light emitted from the exit end of the light guide in a first section. The exit end of the light guide has an aperture that has a size in a first direction perpendicular to the first section, which is larger than a size in a second direction perpendicular to the first direction.
US10105040B2 Imaging needle apparatus
An imaging device includes a needle, an imager, and a syringe. The needle includes a tip. The imager includes a plurality of stacked integrated circuits (ICs). The syringe is coupled to the needle.
US10105036B2 Connector device for a controllable instrument
A connector assembly for controllable articles is described herein. The connector assembly engages force transmission elements used to transmit force from one or more force generators with the force transmission elements used to manipulate a controllable article. Additionally, the connector assembly provides organization thereby simplifying the process of connecting a plurality of elements, usually with a quick, single movement.
US10105033B2 Auxiliary gray water source device for commercial kitchens
An auxiliary gray water supply device captures used wash water from a commercial warewashing machine for supply to a pre-rinse station without substantial modification of the commercial warewashing machine. The captured wash water and treatment agent are delivered to a pre-rinse station for pre-rinsing of dishes that will be washed within the commercial warewashing machine.
US10105024B2 Vacuum cleaner
A vacuum cleaner is provided with a chassis and a suction nozzle coupled with the chassis for both vertical and horizontal movement relative to the chassis. The nozzle can be configured to automatically move vertically upon encountering a predetermined amount of resistance to forward or rearward movement of nozzle over a surface to be cleaned.
US10105023B2 Hand vacuum cleaner
A hand vacuum cleaner having a main body and an air treatment member provided at a front end of the main body.